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Laura Denby

Research Profile

Chemicals & Drugs

Living Beings

Physiology

Transduction, Genetic

Devices

Gene Transfer Techniques

Anatomy

Disorders

Animal Disease Models

Procedures

Serotyping

Co-author Network

Publications

TOP 3
Monica Flores-Munoz; Delyth Graham; Laura Denby; Anna F Dominiczak; Kirsten Douglas; Lorraine M Work; Stuart A Nicklin
Angiotensin-(1-9) attenuates cardiac fibrosis in the stroke-prone spontaneously hypertensive rat via the angiotensin type 2 receptor.
Jenny A Greig; Rachel Shirley; Delyth Graham; Laura Denby; Anna F Dominiczak; Lorraine M Work; Andrew H Baker
Vascular-targeting antioxidant therapy in a model of hypertension and stroke.
Raul Alba; Angela C Bradshaw; Lynda Coughlan; Laura Denby; Robert A McDonald; Simon Waddington; Suzanne M K Buckley; Jenny A Greig; Alan L Parker; Ashley M Miller; Hongjie Wang; André Lieber; Nico van Rooijen; John H McVey; Stuart A Nicklin; Andrew H Baker
Biodistribution and retargeting of FX-binding ablated adenovirus serotype 5 vectors.

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All Publications

2012: Monica Flores-Munoz; Delyth Graham; Laura Denby; Anna F Dominiczak; Kirsten Douglas; Lorraine M Work; Stuart A Nicklin
Angiotensin-(1-9) attenuates cardiac fibrosis in the stroke-prone spontaneously hypertensive rat via the angiotensin type 2 receptor.
Hypertension 2012;59(2):300-7.
2010: Jenny A Greig; Rachel Shirley; Delyth Graham; Laura Denby; Anna F Dominiczak; Lorraine M Work; Andrew H Baker
Vascular-targeting antioxidant therapy in a model of hypertension and stroke.
Journal of cardiovascular pharmacology 2010;56(6):642-50.
2010: Raul Alba; Angela C Bradshaw; Lynda Coughlan; Laura Denby; Robert A McDonald; Simon Waddington; Suzanne M K Buckley; Jenny A Greig; Alan L Parker; Ashley M Miller; Hongjie Wang; André Lieber; Nico van Rooijen; John H McVey; Stuart A Nicklin; Andrew H Baker
Biodistribution and retargeting of FX-binding ablated adenovirus serotype 5 vectors.
Blood 2010;116(15):2656-64.
2010: Paola Caruso; Margaret R MacLean; Raya Khanin; John McClure; Elaine Soon; Mark Southgate; Robert A MacDonald; Jenny A Greig; Keith E Robertson; Rachel Masson; Laura Denby; Yvonne Dempsie; Lu Long; Nicholas W Morrell; Andrew H Baker
Dynamic changes in lung microRNA profiles during the development of pulmonary hypertension due to chronic hypoxia and monocrotaline.
Arteriosclerosis, thrombosis, and vascular biology 2010;30(4):716-23.
2009: Campbell G Nicol; Laura Denby; Oscar Lopez-Franco; Rachel Masson; Crawford A Halliday; Stuart A Nicklin; Angelika Kritz; Lorraine M Work; Andrew H Baker
Use of in vivo phage display to engineer novel adenoviruses for targeted delivery to the cardiac vasculature.
FEBS letters 2009;583(12):2100-7.
2008: Ashley M Miller; Damo Xu; Darren L Asquith; Laura Denby; Yubin Li; Naveed Sattar; Andrew H Baker; Iain B McInnes; Foo Y Liew
IL-33 reduces the development of atherosclerosis.
The Journal of experimental medicine 2008;205(2):339-46.
2008: Simon Waddington; John H McVey; David Bhella; Alan L Parker; Kristeen Barker; Hideko Atoda; Rebecca Pink; Suzanne Buckley; Jenny A Greig; Laura Denby; Jerome Custers; Takashi Morita; Ivo M B Francischetti; Robson Q Monteiro; Dan H Barouch; Nico van Rooijen; Claudio Napoli; Menzo J E Havenga; Stuart A Nicklin; Andrew H Baker
Adenovirus serotype 5 hexon mediates liver gene transfer.
Cell 2008;132(3):397-409.
2007: Laura Denby; Lorraine M Work; Dan J Von Seggern; Eugene Wu; John H McVey; Stuart A Nicklin; Andrew H Baker
Development of renal-targeted vectors through combined in vivo phage display and capsid engineering of adenoviral fibers from serotype 19p.
Molecular therapy : the journal of the American Society of Gene Therapy 2007;15(9):1647-54.
2006: Alan L Parker; Simon Waddington; Campbell G Nicol; Dmitry M Shayakhmetov; Suzanne Buckley; Laura Denby; Geoffrey Kemball-Cook; Shaoheng Ni; André Lieber; John H McVey; Stuart A Nicklin; Andrew H Baker
Multiple vitamin K-dependent coagulation zymogens promote adenovirus-mediated gene delivery to hepatocytes.
Blood 2006;108(8):2554-61.
2006: Lorraine M Work; Hildegard Büning; Ela Hunt; Stuart A Nicklin; Laura Denby; Nicola Britton; Kristin Leike; Margarete Odenthal; Uta Drebber; Michael Hallek; Andrew H Baker
Vascular bed-targeted in vivo gene delivery using tropism-modified adeno-associated viruses.
Molecular therapy : the journal of the American Society of Gene Therapy 2006;13(4):683-93.
2005: Laura Denby; Stuart A Nicklin; Andrew H Baker
Adeno-associated virus (AAV)-7 and -8 poorly transduce vascular endothelial cells and are sensitive to proteasomal degradation.
Gene therapy 2005;12(20):1534-8.
2005: Lorraine M Work; Campbell G Nicol; Laura Denby; Andrew H Baker
In vivo biopanning: A methodological approach to identifying novel targeting ligands for delivery of biological agents to the vasculature.
Methods in molecular medicine 2005;108():395-413.
2004: Laura Denby; Lorraine M Work; Delyth Graham; Catherine Hsu; Dan J Von Seggern; Stuart A Nicklin; Andrew H Baker
Adenoviral serotype 5 vectors pseudotyped with fibers from subgroup D show modified tropism in vitro and in vivo.
Human gene therapy 2004;15(11):1054-64.
2003: Kate L Dishart; Laura Denby; Sarah George; Stuart A Nicklin; Satya Yendluri; Melanie J Tuerk; Michael P Kelley; Brian A Donahue; Andrew C Newby; Thomas C Harding; Andrew H Baker
Third-generation lentivirus vectors efficiently transduce and phenotypically modify vascular cells: implications for gene therapy.
Journal of molecular and cellular cardiology 2003;35(7):739-48.