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Carl Denef

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Katrien Pals; M Roudbaraki; Carl Denef
Growth hormone-releasing hormone and glucocorticoids determine the balance between luteinising hormone (LH) beta- and LH beta/follicle-stimulating hormone beta-positive gonadotrophs and somatotrophs in the 14-day-old rat pituitary tissue in aggregate cell culture.
Kristel Janssens; Magaly Boussemaere; Stefan Wagner; Klaus Kopka; Carl Denef
Beta1-adrenoceptors in rat anterior pituitary may be constitutively active. Inverse agonism of CGP 20712A on basal 3',5'-cyclic adenosine 5'-monophosphate levels.
Kristel Janssens; Olga Krylyshkina; Nicole Hersmus; Hugo Vankelecom; Carl Denef
Beta1-adrenoceptor expression in rat anterior pituitary gonadotrophs and in mouse alphaT3-1 and LbetaT2 gonadotrophic cell lines.

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All Publications

2008: Katrien Pals; M Roudbaraki; Carl Denef
Growth hormone-releasing hormone and glucocorticoids determine the balance between luteinising hormone (LH) beta- and LH beta/follicle-stimulating hormone beta-positive gonadotrophs and somatotrophs in the 14-day-old rat pituitary tissue in aggregate cell culture.
Journal of neuroendocrinology 2008;20(5):535-48.
2008: Kristel Janssens; Magaly Boussemaere; Stefan Wagner; Klaus Kopka; Carl Denef
Beta1-adrenoceptors in rat anterior pituitary may be constitutively active. Inverse agonism of CGP 20712A on basal 3',5'-cyclic adenosine 5'-monophosphate levels.
Endocrinology 2008;149(5):2391-402.
2008: Kristel Janssens; Olga Krylyshkina; Nicole Hersmus; Hugo Vankelecom; Carl Denef
Beta1-adrenoceptor expression in rat anterior pituitary gonadotrophs and in mouse alphaT3-1 and LbetaT2 gonadotrophic cell lines.
Endocrinology 2008;149(5):2313-24.
2008: Carl Denef
Paracrinicity: the story of 30 years of cellular pituitary crosstalk.
Journal of neuroendocrinology 2008;20(1):1-70.
2007: A Papageorgiou; Carl Denef
Stimulation of growth hormone release by 5-hydroxytryptamine (5-HT) in cultured rat anterior pituitary cell aggregates: evidence for mediation by 5-HT2B, 5-HT7, 5-HT1B, and ketanserin-sensitive receptors.
Endocrinology 2007;148(9):4509-22.
2007: A Papageorgiou; Carl Denef
Estradiol induces expression of 5-hydroxytryptamine (5-HT) 4, 5-HT5, and 5-HT6 receptor messenger ribonucleic acid in rat anterior pituitary cell aggregates and allows prolactin release via the 5-HT4 receptor.
Endocrinology 2007;148(3):1384-95.
2006: Pieter Van As; Koen Janssens; Katrien Pals; Bert De Groef; Okanlawon Onagbesan; Veerle Bruggeman; Veerle M Darras; Carl Denef; Eddy Decuypere
The chicken pituitary-specific transcription factor PIT-1 is involved in the hypothalamic regulation of pituitary hormones.
Acta veterinaria Hungarica 2006;54(4):455-71.
2006: Leentje Van Lommel; Koen Janssens; Roel Quintens; Katsura Tsukamoto; Dirk Vander Mierde; Katleen Lemaire; Carl Denef; Jean-Christophe Jonas; Geert Martens; Daniel Pipeleers; Frans Schuit
Probe-independent and direct quantification of insulin mRNA and growth hormone mRNA in enriched cell preparations.
Diabetes 2006;55(12):3214-20.
2006: Katrien Pals; M Boussemaere; E Swinnen; Hugo Vankelecom; Carl Denef
A Pituitary cell type coexpressing messenger ribonucleic acid of proopiomelanocortin and the glycoprotein hormone alpha-subunit in neonatal rat and chicken: rapid decline with age and reappearance in vitro under regulatory pressure of corticotropin-releasing hormone in the rat.
Endocrinology 2006;147(10):4738-52.
2006: Katrien Pals; Hugo Vankelecom; Carl Denef
Triiodothyronine expands the lactotroph and maintains the lactosomatotroph population, whereas thyrotrophin-releasing hormone augments thyrotroph abundance in aggregate cell cultures of postnatal rat pituitary gland.
Journal of neuroendocrinology 2006;18(3):203-16.
2005: Jianghai Chen; Nicole Hersmus; Vik Van Duppen; Pieter Caesens; Carl Denef; Hugo Vankelecom
The adult pituitary contains a cell population displaying stem/progenitor cell and early embryonic characteristics.
Endocrinology 2005;146(9):3985-98.
2005: E Swinnen; M Boussemaere; Carl Denef
Stimulation and inhibition of prolactin release by prolactin-releasing Peptide in rat anterior pituitary cell aggregates.
Journal of neuroendocrinology 2005;17(6):379-86.
2005: Olga Krylyshkina; Jianghai Chen; Liese Mebis; Carl Denef; Hugo Vankelecom
Nestin-immunoreactive cells in rat pituitary are neither hormonal nor typical folliculo-stellate cells.
Endocrinology 2005;146(5):2376-87.
2005: Carl Denef; Katrien Pals; Annelies Hauspie; Hugo Vankelecom; Eve Seuntjens
Combinatorial expression of phenotypes of different cell lineages in the rat and mouse pituitary.
Annals of the New York Academy of Sciences 2005;1040():84-8.
2004: Karen Hensen; Caroline V Braem; Jeroen Declercq; Frederik Van Dyck; Mieke Dewerchin; Laurence Fiette; Carl Denef; Wim J M Van De Ven
Targeted disruption of the murine Plag1 proto-oncogene causes growth retardation and reduced fertility.
Development, growth & differentiation 2004;46(5):459-70.
2004: Lies Langouche; Nicole Hersmus; A Papageorgiou; Hugo Vankelecom; Carl Denef
Melanocortin peptides stimulate prolactin gene expression and prolactin accumulation in rat pituitary aggregate cell cultures.
Journal of neuroendocrinology 2004;16(8):695-703.
2003: Hugo Vankelecom; Eve Seuntjens; Annelies Hauspie; Carl Denef
Targeted ablation of gonadotrophs in transgenic mice depresses prolactin but not growth hormone gene expression at birth as measured by quantitative mRNA detection.
Journal of biomedical science 2003;10(6 Pt 2):805-12.
2003: Carl Denef; J Lu; E Swinnen
Gamma-MSH peptides in the pituitary: effects, target cells, and receptors.
Annals of the New York Academy of Sciences 2003;994():123-32.
2003: Carl Denef
Paracrine control of lactotrope proliferation and differentiation.
Trends in endocrinology and metabolism: TEM 2003;14(4):188-95.
2003: Annelies Hauspie; Eve Seuntjens; Hugo Vankelecom; Carl Denef
Stimulation of combinatorial expression of prolactin and glycoprotein hormone alpha-subunit genes by gonadotropin-releasing hormone and estradiol-17beta in single rat pituitary cells during aggregate cell culture.
Endocrinology 2003;144(1):388-99.
2002: J Lu; E Swinnen; Paul Proost; B De Vreese; Hugo Vankelecom; Carl Denef
Isolation and structure-bioactivity characterization of glycosylated N-pro-opiomelanocortin isoforms.
Journal of neuroendocrinology 2002;14(11):869-79.
2002: David Cassiman; Louis Libbrecht; Nicoletta Sinelli; Valeer Desmet; Carl Denef; Tania Roskams
The vagal nerve stimulates activation of the hepatic progenitor cell compartment via muscarinic acetylcholine receptor type 3.
The American journal of pathology 2002;161(2):521-30.
2002: Eve Seuntjens; Annelies Hauspie; Hugo Vankelecom; Carl Denef
Ontogeny of plurihormonal cells in the anterior pituitary of the mouse, as studied by means of hormone mRNA detection in single cells.
Journal of neuroendocrinology 2002;14(8):611-9.
2002: Dirk Ramaekers; Frank Beckers; Hilde Demeulemeester; Christophe Bert; Carl Denef; André E Aubert
Effects of melanocortins on cardiovascular regulation in rats.
Clinical and experimental pharmacology & physiology 2002;29(7):549-58.
2002: Lies Langouche; Katrien Pals; Carl Denef
Structure-activity relationship and signal transduction of gamma-MSH peptides in GH3 cells: further evidence for a new melanocortin receptor.
Peptides 2002;23(6):1077-86.
2002: Eve Seuntjens; Annelies Hauspie; M Roudbaraki; Hugo Vankelecom; Carl Denef
Combined expression of different hormone genes in single cells of normal rat and mouse pituitary.
Archives of physiology and biochemistry 2002;110(1-2):12-5.
2002: David Cassiman; Louis Libbrecht; Valeer Desmet; Carl Denef; Tania Roskams
Hepatic stellate cell/myofibroblast subpopulations in fibrotic human and rat livers.
Journal of hepatology 2002;36(2):200-9.
2001: David Cassiman; Tania Roskams; Jos van Pelt; Louis Libbrecht; P Aertsen; Tina Crabbé; Hugo Vankelecom; Carl Denef
Alpha B-crystallin expression in human and rat hepatic stellate cells.
Journal of hepatology 2001;35(2):200-7.
2001: Carl Denef; M Roudbaraki; A Van Bael
Growth and differentiation factors derived from the N-terminal domain of pro-opiomelanocortin.
Clinical and experimental pharmacology & physiology 2001;28(3):239-43.
2001: Lies Langouche; M Roudbaraki; Katrien Pals; Carl Denef
Stimulation of intracellular free calcium in GH3 cells by gamma3-melanocyte-stimulating hormone. Involvement of a novel melanocortin receptor?
Endocrinology 2001;142(1):257-66.
2001: David Cassiman; Carl Denef; Valeer Desmet; Tania Roskams
Human and rat hepatic stellate cells express neurotrophins and neurotrophin receptors.
Hepatology (Baltimore, Md.) 2001;33(1):148-58.
1999: André E Aubert; Dirk Ramaekers; Frank Beckers; R Breem; Carl Denef; Frans Van de Werf; Hugo Ector
The analysis of heart rate variability in unrestrained rats. Validation of method and results.
Computer methods and programs in biomedicine 1999;60(3):197-213.
1999: M Roudbaraki; A Lorsignol; Lies Langouche; G Callewaert; Hugo Vankelecom; Carl Denef
Target cells of gamma3-melanocyte-stimulating hormone detected through intracellular Ca2+ responses in immature rat pituitary constitute a fraction of all main pituitary cell types, but mostly express multiple hormone phenotypes at the messenger ribonucleic acid level. Refractoriness to melanocortin-3 receptor blockade in the lacto-somatotroph lineage.
Endocrinology 1999;140(10):4874-85.
1999: Christophe Bert; V Vande Vijver; Maria Andries; Peter Verhaert; Paul Proost; B De Vreese; Jozef Van Beeumen; Hugo Vankelecom; Carl Denef
Production of recombinant rat proopiomelanocortin1-74 and characterization of its mitogenic action on pituitary lactotrophs.
Molecular and cellular endocrinology 1999;154(1-2):111-22.
1999: Eve Seuntjens; Hugo Vankelecom; A Quaegebeur; V Vande Vijver; Carl Denef
Targeted ablation of gonadotrophs in transgenic mice affects embryonic development of lactotrophs.
Molecular and cellular endocrinology 1999;150(1-2):129-39.
1999: Eve Seuntjens; Carl Denef
Progenitor cells in the embryonic anterior pituitary abruptly and concurrently depress mitotic rate before progressing to terminal differentiation.
Molecular and cellular endocrinology 1999;150(1-2):57-63.
1999: A Lorsignol; V Vande Vijver; Dirk Ramaekers; Hugo Vankelecom; Carl Denef
Detection of melanocortin-3 receptor mRNA in immature rat pituitary: functional relation to gamma3-MSH-induced changes in intracellular Ca2+ concentration?
Journal of neuroendocrinology 1999;11(3):171-9.
1998: Carl Denef; A Van Bael
A new family of growth and differentiation factors derived from the N-terminal domain of proopiomelanocortin (N-POMC).
Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology 1998;119(3):317-24.
1998: A Van Bael; Eve Seuntjens; Marijke Proesmans; Carl Denef
Presence of gonadotropin-releasing hormone (GnRH) mRNA in Rathke's pouch and effect of the GnRH-antagonist ORG 30276 on lactotroph development in vitro.
Journal of neuroendocrinology 1998;10(6):437-45.
1998: A Lorsignol; Bernard Himpens; Carl Denef
Stimulation of Ca2+ entry in lactotrophs and somatotrophs from immature rat pituitary by N-terminal fragments of proopiomelanocortin.
Journal of neuroendocrinology 1998;10(3):217-29.
1997: Marijke Proesmans; A Van Bael; Maria Andries; Carl Denef
Mitogenic effects of nerve growth factor on different cell types in reaggregate cell cultures of immature rat pituitary.
Molecular and cellular endocrinology 1997;134(2):119-27.
1997: Dirk Ramaekers; Marijke Proesmans; Carl Denef
Expression of the low-affinity p75 nerve growth factor receptor in the developing rat pituitary gland.
Neurochemical research 1997;22(11):1353-7.
1997: Hugo Vankelecom; Carl Denef
Paracrine communication in the anterior pituitary as studied in reaggregate cell cultures.
Microscopy research and technique 1997;39(2):150-6.
1997: D Tilemans; Dirk Ramaekers; Maria Andries; Carl Denef
Effect of POMC(1-76), its C-terminal fragment gamma3-MSH and anti-POMC(1-76) antibodies on DNA replication in lactotrophs in aggregate cell cultures of immature rat pituitary.
Journal of neuroendocrinology 1997;9(8):627-37.
1997: Hugo Vankelecom; Patrick Matthys; Carl Denef
Inducible nitric oxide synthase in the anterior pituitary gland: induction by interferon-gamma in a subpopulation of folliculostellate cells and in an unidentifiable population of non-hormone-secreting cells.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1997;45(6):847-57.
1997: Hugo Vankelecom; Patrick Matthys; Carl Denef
Involvement of nitric oxide in the interferon-gamma-induced inhibition of growth hormone and prolactin secretion in anterior pituitary cell cultures.
Molecular and cellular endocrinology 1997;129(2):157-67.
1996: Maria Andries; G F Jacobs; D Tilemans; Carl Denef
In vitro immunoneutralization of a cleaved prolactin variant: evidence for a local paracrine action of cleaved prolactin in the development of gonadotrophs and thyrotrophs in rat pituitary.
Journal of neuroendocrinology 1996;8(2):123-7.
1996: A Van Bael; Carl Denef
Evidence for a trophic action of the glycoprotein hormone alpha-subunit in rat pituitary.
Journal of neuroendocrinology 1996;8(2):99-102.
1996: A Van Bael; V Vande Vijver; Bart Devreese; J Van Beeumen; Carl Denef
N-terminal 10- and 12-kDa POMC fragments stimulate differentiation of lactotrophs.
Peptides 1996;17(7):1219-28.
1995: D Tilemans; V V Vijver; G Verhoeven; Carl Denef
Production of transferrin-like immunoreactivity by rat anterior pituitary and intermediate lobe.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1995;43(7):657-64.
1995: Maria Andries; V Vande Vijver; D Tilemans; C Bert; Carl Denef
Interaction of alpha T3-1 cells with lactotropes and somatotropes of normal pituitary in vitro.
Neuroendocrinology 1995;61(3):326-36.
1995: A Van Bael; Marijke Proesmans; D Tilemans; Carl Denef
Interaction of LHRH with growth hormone-releasing factor-dependent and -independent postnatal development of somatotrophs in rat pituitary cell aggregates.
Journal of molecular endocrinology 1995;14(1):91-100.
1995: Maria Andries; Carl Denef
Gonadotropin-releasing hormone influences the release of prolactin and growth hormone from intact rat pituitary in vitro during a limited period in neonatal life.
Peptides 1995;16(3):527-32.
1994: D Tilemans; Maria Andries; Paul Proost; Bart Devreese; J Van Beeumen; Carl Denef
In vitro evidence that an 11-kilodalton N-terminal fragment of proopiomelanocortin is a growth factor specifically stimulating the development of lactotrophs in rat pituitary during postnatal life.
Endocrinology 1994;135(1):168-74.
1994: A Van Bael; R Huygen; B Himpens; Carl Denef
In vitro evidence that LHRH stimulates the recruitment of prolactin mRNA-expressing cells during the postnatal period in the rat.
Journal of molecular endocrinology 1994;12(1):107-18.
1994: Maria Andries; D Tilemans; Carl Denef
Modulation of epidermal growth factor receptor binding and action by N-acetyl-TGF alpha (34-43) methyl ester.
Peptides 1994;15(4):619-25.
1994: H Houben; Carl Denef
Bioactive peptides in anterior pituitary cells.
Peptides 1994;15(3):547-82.
1994: D Tilemans; G F Jacobs; Maria Andries; Paul Proost; Bart Devreese; Jo Van Damme; J Van Beeumen; Carl Denef
Isolation of two peptides from rat gonadotroph-conditioned medium displaying an amino acid sequence identical to fragments of secretogranin II.
Peptides 1994;15(3):537-45.
1994: H Houben; Maria Andries; Carl Denef
Autoradiographic demonstration of 125I-Tyr4-bombesin binding sites on rat anterior pituitary cells.
Peptides 1994;15(7):1289-95.
1993: H Houben; A T Vandenbroucke; A M Verheyden; Carl Denef
Expression of the genes encoding bombesin-related peptides and their receptors in anterior pituitary tissue.
Molecular and cellular endocrinology 1993;97(1-2):159-64.
1993: Hugo Vankelecom; Patrick Matthys; Jo Van Damme; Hubertine Heremans; An D Billiau; Carl Denef
Immunocytochemical evidence that S-100-positive cells of the mouse anterior pituitary contain interleukin-6 immunoreactivity.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1993;41(2):151-6.
1993: H Houben; Carl Denef
Unexpected effects of peptide and nonpeptide substance P receptor antagonists on basal prolactin and growth hormone release in vitro.
Peptides 1993;14(1):109-15.
1992: Wim Robberecht; Maria Andries; Carl Denef
Angiotensin II is retained in gonadotrophs of pituitary cell aggregates cultured in serum-free medium but does not mimic the effects of exogenous angiotensins and luteinizing-hormone-releasing hormone on growth hormone release.
Neuroendocrinology 1992;56(4):550-60.
1992: Wim Robberecht; Maria Andries; Carl Denef
Stimulation of prolactin secretion from rat pituitary by luteinizing hormone-releasing hormone: evidence against mediation by angiotensin II acting through a (Sar1-Ala8)-angiotensin II-sensitive receptor.
Neuroendocrinology 1992;56(2):185-94.
1992: Hugo Vankelecom; Maria Andries; An D Billiau; Carl Denef
Evidence that folliculo-stellate cells mediate the inhibitory effect of interferon-gamma on hormone secretion in rat anterior pituitary cell cultures.
Endocrinology 1992;130(6):3537-46.
1992: D Tilemans; Maria Andries; Carl Denef
Luteinizing hormone-releasing hormone and neuropeptide Y influence deoxyribonucleic acid replication in three anterior pituitary cell types. Evidence for mediation by growth factors released from gonadotrophs.
Endocrinology 1992;130(2):882-94.
1992: Maria Andries; D Tilemans; Carl Denef
Isolation of cleaved prolactin variants that stimulate DNA synthesis in specific cell types in rat pituitary cell aggregates in culture.
The Biochemical journal 1992;281 ( Pt 2)():393-400.
1992: H Houben; Carl Denef
Negative regulation by dexamethasone of the potentiation of neuromedin C-induced growth hormone and prolactin release by estradiol in anterior pituitary cell aggregates.
Life sciences 1992;50(11):775-80.
1991: H Houben; Carl Denef
Evidence for the presence of gastrin-releasing peptide immunoreactivity in rat anterior pituitary corticotrophs and lactotrophs, AtT20 cells, and GH3 cells: failure to demonstrate participation in local control of hormone release.
Endocrinology 1991;128(6):3208-18.
1991: H Houben; Carl Denef
Effect of the bombesin receptor blockers [Leu13, psi CH2NH-Leu14]bombesin and N-pivaloyl GRP(20-25) alkylamide (L 686,095-001C002) on basal and neuromedin C-stimulated PRL and GH release in pituitary cell aggregates.
Peptides 1991;12(2):371-4.
1991: W Allaerts; A Mignon; Carl Denef
Selectivity of juxtaposition between cup-shaped lactotrophs and gonadotrophs from rat anterior pituitary in culture.
Cell and tissue research 1991;263(2):217-25.
1991: Peter Carmeliet; Hugo Vankelecom; Jo Van Damme; An D Billiau; Carl Denef
Release of interleukin-6 from anterior pituitary cell aggregates: developmental pattern and modulation by glucocorticoids and forskolin.
Neuroendocrinology 1991;53(1):29-34.
1990: Wim Robberecht; Carl Denef
Evidence for a pertussis toxin-sensitive signalling pathway in the dual action of angiotensin II on growth hormone release in pituitary cell aggregates.
Cell biology international reports 1990;14(11):1001-11.
1990: H Houben; D Tilemans; Carl Denef
Towards a functional significance of peptides and biogenic amines produced by the anterior pituitary.
Journal of endocrinological investigation 1990;13(10):855-63.
1990: W Allaerts; Y Engelborghs; P Van Oostveldt; Carl Denef
Evidence that folliculo-stellate cells do not impede the permeability of intercellular spaces to molecular diffusion in three-dimensional aggregate cell cultures of rat anterior pituitary.
Endocrinology 1990;127(3):1517-25.
1990: Karl Bauer; Peter Carmeliet; M Schulz; Myriam Baes; Carl Denef
Regulation and cellular localization of the membrane-bound thyrotropin-releasing hormone-degrading enzyme in primary cultures of neuronal, glial and adenohypophyseal cells.
Endocrinology 1990;127(3):1224-33.
1990: W Allaerts; Peter Carmeliet; Carl Denef
New perspectives in the function of pituitary folliculo-stellate cells.
Molecular and cellular endocrinology 1990;71(2):73-81.
1990: Hugo Vankelecom; Peter Carmeliet; Hubertine Heremans; Jo Van Damme; R Dijkmans; An D Billiau; Carl Denef
Interferon-gamma inhibits stimulated adrenocorticotropin, prolactin, and growth hormone secretion in normal rat anterior pituitary cell cultures.
Endocrinology 1990;126(6):2919-26.
1990: H Houben; Carl Denef
Stimulation of growth hormone and prolactin release from rat pituitary cell aggregates by bombesin- and ranatensin-like peptides is potentiated by estradiol, 5 alpha-dihydrotestosterone, and dexamethasone.
Endocrinology 1990;126(5):2257-66.
1990: Carl Denef
[Paracrine signals in the adenohypophysis].
Verhandelingen - Koninklijke Academie voor Geneeskunde van België 1990;52(4):353-69.
1989: Peter Carmeliet; P Maertens; Carl Denef
Stimulation and inhibition of prolactin release from rat pituitary lactotrophs by the cholinomimetic carbachol in vitro. Influence of hormonal environment and intercellular contacts.
Molecular and cellular endocrinology 1989;63(1-2):121-31.
1989: Peter Carmeliet; Myriam Baes; Carl Denef
The glucocorticoid hormone dexamethasone reverses the growth hormone-releasing properties of the cholinomimetic carbachol.
Endocrinology 1989;124(5):2625-34.
1989: Peter Carmeliet; Carl Denef
Synthesis and release of acetylcholine by normal and tumoral pituitary corticotrophs.
Endocrinology 1989;124(5):2218-27.
1989: W Allaerts; Carl Denef
Regulatory activity and topological distribution of folliculo-stellate cells in rat anterior pituitary cell aggregates.
Neuroendocrinology 1989;49(4):409-18.
1989: Hugo Vankelecom; Peter Carmeliet; Jo Van Damme; An D Billiau; Carl Denef
Production of interleukin-6 by folliculo-stellate cells of the anterior pituitary gland in a histiotypic cell aggregate culture system.
Neuroendocrinology 1989;49(1):102-6.
1989: Carl Denef; P Maertens; W Allaerts; A Mignon; W Robberecht; L Swennen; Peter Carmeliet
Cell-to-cell communication in peptide target cells of anterior pituitary.
Methods in enzymology 1989;168():47-71.
1988: Wim Robberecht; Carl Denef
Enhanced ANG II activity in anterior pituitary cell aggregates from hypertensive rats.
The American journal of physiology 1988;255(3 Pt 2):R407-11.
1988: Peter Carmeliet; Carl Denef
Immunocytochemical and pharmacological evidence for an intrinsic cholinomimetic system modulating prolactin and growth hormone release in rat pituitary.
Endocrinology 1988;123(2):1128-39.
1988: W Allaerts; A Wouters; D Van der Massen; A Persoons; Carl Denef
A diffusion-adsorption model for the computation of the amount of hormone around a secreting cell, detected by the reverse hemolytic plaque assay.
Journal of theoretical biology 1988;131(4):441-59.
1988: Wim Robberecht; Carl Denef
Stimulation and inhibition of pituitary growth hormone release by angiotensin II in vitro.
Endocrinology 1988;122(4):1496-504.
1987: P Maertens; Carl Denef
Alpha-adrenergic stimulation of growth hormone release in perifused rat anterior pituitary reaggregate cell cultures.
Molecular and cellular endocrinology 1987;54(2-3):203-11.
1987: M Baes; W Allaerts; Carl Denef
Evidence for functional communication between folliculo-stellate cells and hormone-secreting cells in perifused anterior pituitary cell aggregates.
Endocrinology 1987;120(2):685-91.
1986: TR Koiter; Carl Denef; Maria Andries; Henk Moes; Gerard A Schuiling
The prolonged action of the LHRH agonist buserelin (HOE 766) may be due to prolonged binding to the LHRH receptor.
Life sciences 1986;39(5):443-52.
1986: Maria Andries; Carl Denef
Characterization of luteinizing hormone-releasing hormone receptor binding in rat pituitary cell monolayer cultures; influence of intercellular communication.
Molecular and cellular endocrinology 1986;44(2):147-58.
1985: Carl Denef; C Schramme
Regulation of prolactin release by angiotensin.
Hormone research 1985;22(3):135-41.
1985: Carl Denef; C Schramme; M Baes
Stimulation of growth hormone release by vasoactive intestinal peptide and peptide PHI in rat anterior pituitary reaggregates. Permissive action of a glucocorticoid and inhibition by thyrotropin-releasing hormone.
Neuroendocrinology 1985;40(1):88-91.
1985: L Swennen; M Baes; C Schramme; Carl Denef
Beta-adrenergic stimulation of adenosine-3',5'-monophosphate (c-AMP) in primary cultures of rat anterior pituitary cell populations separated by unit gravity sedimentation. Relationship to growth hormone and prolactin release and to nonsecreting cells.
Neuroendocrinology 1985;40(1):78-83.
1985: L Swennen; M Baes; Carl Denef
Beta-adrenergic stimulation of adenosine-3',5'-monophosphate (c-AMP) accumulation and of prolactin and growth hormone secretion in rat anterior pituitary cell cultures.
Neuroendocrinology 1985;40(1):72-7.
1984: C Schramme; Carl Denef
Stimulation of spontaneous and dopamine-inhibited prolactin release from anterior pituitary reaggregate cell cultures by angiotensin peptides.
Life sciences 1984;34(17):1651-8.
1984: Carl Denef; M Baes; C Schramme
Stimulation of prolactin secretion after short term or pulsatile exposure to dopamine in superfused anterior pituitary cell aggregates.
Endocrinology 1984;114(4):1371-8.
1984: Carl Denef; C Schramme; M Baes
Influence of corticosteroids on prolactin release from anterior pituitary cell aggregates cultured in serum-free medium. Differential effects on dopamine-induced inhibition, post-dopamine rebound and stimulation by TRH, vasoactive intestinal peptide (VIP), angiotensin II and isoproterenol.
Journal of steroid biochemistry 1984;20(1):197-202.
1983: C Schramme; Carl Denef
Stimulation of prolactin release by angiotensin II in superfused rat anterior pituitary cell aggregates.
Neuroendocrinology 1983;36(6):483-5.
1983: C Schramme; Carl Denef
Stimulation of prolactin release by angiotensin II in superfused rat anterior pituitary cell aggregates.
Archives internationales de pharmacodynamie et de thérapie 1983;262(2):330-1.
1983: Carl Denef; Maria Andries
Evidence for paracrine interaction between gonadotrophs and lactotrophs in pituitary cell aggregates.
Endocrinology 1983;112(3):813-22.
1982: L Swennen; Carl Denef
Physiological concentrations of dopamine decrease adenosine 3',5'-monophosphate levels in cultured rat anterior pituitary cells and enriched populations of lactotrophs: evidence for a causal relationship to inhibition of prolactin release.
Endocrinology 1982;111(2):398-405.
1982: L Swennen; Carl Denef; P Van Gompel; J E Leysen
Effect of dopamine on plasma membrane phospholipid methylation of cultured anterior pituitary cells.
Archives internationales de pharmacodynamie et de thérapie 1982;256(2):317-9.
1982: L Swennen; Carl Denef
c-AMP levels decreased by dopamine in cultured rat pituitary lactotrophs.
Archives internationales de pharmacodynamie et de thérapie 1982;256(2):315-6.
1982: Maria Andries; Carl Denef
Specific binding of a superagonist analog of gonadotropin releasing hormone (GnRH) to rat pituitary cells and purified gonadotrophs in primary culture.
Archives internationales de pharmacodynamie et de thérapie 1982;256(1):145-7.
1982: Carl Denef; L Swennen; Maria Andries
Separated anterior pituitary cells and their response to hypophysiotropic hormones.
International review of cytology 1982;76():225-44.