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Han-Wu Deng

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Myocardial Ischemic Preconditioning

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Xiao-Qing Zou; Sheng-Ming Peng; Chang-Ping Hu; Li-Feng Tan; Han-Wu Deng; Yuan-Jian Li
Furoxan nitric oxide donor coupled chrysin derivatives: synthesis and vasculoprotection.
Su-Jie Jia; Bi-Kui Zhang; Yong-Quan Lai; Han-Wu Deng; Yuan-Jian Li
3,4,5,6-Tetrahydroxyxanthone preserves intercellular communication by reduction of the endogenous nitric oxide synthase inhibitor level.
Jian-Zhe Li; Jun Peng; Li Xiao; Yi-Shuai Zhang; Mei-Chun Liao; Xiao-Hui Li; Chang-Ping Hu; Han-Wu Deng; Yuan-Jian Li
Reversal of isoprenaline-induced cardiac remodeling by rutaecarpine via stimulation of calcitonin gene-related peptide production.

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All Publications

2011: Xiao-Qing Zou; Sheng-Ming Peng; Chang-Ping Hu; Li-Feng Tan; Han-Wu Deng; Yuan-Jian Li
Furoxan nitric oxide donor coupled chrysin derivatives: synthesis and vasculoprotection.
Bioorganic & medicinal chemistry letters 2011;21(4):1222-6.
2011: Su-Jie Jia; Bi-Kui Zhang; Yong-Quan Lai; Han-Wu Deng; Yuan-Jian Li
3,4,5,6-Tetrahydroxyxanthone preserves intercellular communication by reduction of the endogenous nitric oxide synthase inhibitor level.
Journal of Asian natural products research 2011;13(1):20-6.
2010: Jian-Zhe Li; Jun Peng; Li Xiao; Yi-Shuai Zhang; Mei-Chun Liao; Xiao-Hui Li; Chang-Ping Hu; Han-Wu Deng; Yuan-Jian Li
Reversal of isoprenaline-induced cardiac remodeling by rutaecarpine via stimulation of calcitonin gene-related peptide production.
Canadian journal of physiology and pharmacology 2010;88(10):949-59.
2010: Xiao-Qing Zou; Sheng-Ming Peng; Chang-Ping Hu; Li-Feng Tan; Qiong Yuan; Han-Wu Deng; Yuan-Jian Li
Synthesis, characterization and vasculoprotective effects of nitric oxide-donating derivatives of chrysin.
Bioorganic & medicinal chemistry 2010;18(9):3020-5.
2009: Su-Jie Jia; Zhi Zhou; Bi-Kui Zhang; Zhuo-Wei Hu; Han-Wu Deng; Yuan-Jian Li
Asymmetric dimethylarginine damages connexin43-mediated endothelial gap junction intercellular communication.
Biochemistry and cell biology = Biochimie et biologie cellulaire 2009;87(6):867-74.
2009: Gan Zhou; Zhi-Rong Tan; Wei Zhang; Dong-Sheng Ou-Yang; Yao Chen; Dong Guo; Ying-zi Liu; Lan Fan; Han-Wu Deng
An improved LC-MS/MS method for quantitative determination of ilaprazole and its metabolites in human plasma and its application to a pharmacokinetic study.
Acta pharmacologica Sinica 2009;30(9):1330-6.
2009: Dai Li; Xiao-Jie Zhang; Lei Chen; Zhichun Yang; Han-Wu Deng; June Peng; Yuan-Jian Li
Calcitonin gene-related peptide mediates the cardioprotective effects of rutaecarpine against ischaemia-reperfusion injury in spontaneously hypertensive rats.
Clinical and experimental pharmacology & physiology 2009;36(7):662-7.
2009: Dai Li; Ben-Mei Chen; Jun Peng; Yi-Shuai Zhang; Xiao-Hui Li; Qiong Yuan; Chang-Ping Hu; Han-Wu Deng; Yuan-Jian Li
Role of anandamide transporter in regulating calcitonin gene-related peptide production and blood pressure in hypertension.
Journal of hypertension 2009;27(6):1224-32.
2008: Dan Luo; Yi-Wei Zhang; Wei-Jie Peng; Jun Peng; Qing-Quan Chen; Dai Li; Han-Wu Deng; Yuan-Jian Li
Transient receptor potential vanilloid 1-mediated expression and secretion of endothelial cell-derived calcitonin gene-related peptide.
Regulatory peptides 2008;150(1-3):66-72.
2008: Dai Li; Jun Peng; Hong-Ya Xin; Dan Luo; Yi-Shuai Zhang; Zhi Zhou; De-Jian Jiang; Han-Wu Deng; Yuan-Jian Li
Calcitonin gene-related peptide-mediated antihypertensive and anti-platelet effects by rutaecarpine in spontaneously hypertensive rats.
Peptides 2008;29(10):1781-8.
2008: Sheng-Dan Nie; Chang-Ping Hu; Yue-Rong Chen; Shan Wang; Han-Wu Deng; Yuan-Jian Li
Reversal of tolerance to nitroglycerin with vinpocetine: a role of calcitonin gene-related peptide.
International journal of cardiology 2008;125(3):436-8.
2008: Dai Li; Nian-Sheng Li; Qing-Quan Chen; Ren Guo; Ping-Sheng Xu; Han-Wu Deng; Yuan-Jian Li
Calcitonin gene-related peptide-mediated cardioprotection of postconditioning in isolated rat hearts.
Regulatory peptides 2008;147(1-3):4-8.
2007: Shu-Feng Lei; Hui Jiang; Fei-Yan Deng; Han-Wu Deng
Searching for genes underlying susceptibility to osteoporotic fracture: current progress and future prospect.
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 2007;18(9):1157-75.
2007: Dai Li; Ke Xia; Nian-Sheng Li; Dan Luo; Shan Wang; De-Jian Jiang; Han-Wu Deng; Yuan-Jian Li
Reduction of asymmetric dimethylarginine involved in the cardioprotective effect of losartan in spontaneously hypertensive rats.
Canadian journal of physiology and pharmacology 2007;85(8):783-9.
2007: Hong-Bo Xiao; Zhi-Chun Yang; Su-Jie Jia; Nian-Sheng Li; De-Jian Jiang; Xiao-Hong Zhang; Ren Guo; Zhi Zhou; Han-Wu Deng; Yuan-Jian Li
Effect of asymmetric dimethylarginine on atherogenesis and erythrocyte deformability in apolipoprotein E deficient mice.
Life sciences 2007;81(1):1-7.
2007: Qiong Yuan; De-Jian Jiang; Qing-Quan Chen; Shan Wang; Hong-Ya Xin; Han-Wu Deng; Yuan-Jian Li
Role of asymmetric dimethylarginine in homocysteine-induced apoptosis of vascular smooth muscle cells.
Biochemical and biophysical research communications 2007;356(4):880-5.
2007: Feng Ye; Pan-Yue Deng; Dai Li; Dan Luo; Nian-Sheng Li; Sheng Deng; Han-Wu Deng; Yuan-Jian Li
Involvement of endothelial cell-derived CGRP in heat stress-induced protection of endothelial function.
Vascular pharmacology 2007;46(4):238-46.
2007: Zhi-Chun Yang; Ke Xia; Li Wang; Su-Jie Jia; Dai Li; Zhe Zhang; Shen Deng; Xiao-Hong Zhang; Han-Wu Deng; Yuan-Jian Li
Asymmetric dimethylarginine reduced erythrocyte deformability in streptozotocin-induced diabetic rats.
Microvascular research 2007;73(2):131-6.
2007: Jun-Lin Jiang; Shan Wang; Nian-Sheng Li; Xiao-Hong Zhang; Han-Wu Deng; Yuan-Jian Li
The inhibitory effect of simvastatin on the ADMA-induced inflammatory reaction is mediated by MAPK pathways in endothelial cells.
Biochemistry and cell biology = Biochimie et biologie cellulaire 2007;85(1):66-77.
2006: Jun-Lin Jiang; Xiao-Hong Zhang; Nian-Sheng Li; Wei-Qing Rang; Chang-Ping Hu; Yuan-Jian Li; Han-Wu Deng
Probucol decreases asymmetrical dimethylarginine level by alternation of protein arginine methyltransferase I and dimethylarginine dimethylaminohydrolase activity.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 2006;20(4):281-94.
2006: Jian-Guo Cao; Shu-Ping Peng; Li Sun; Hui Li; Li Wang; Han-Wu Deng
Vascular basement membrane-derived multifunctional peptide, a novel inhibitor of angiogenesis and tumor growth.
Acta biochimica et biophysica Sinica 2006;38(7):514-21.
2006: Su-Jie Jia; De-Jian Jiang; Chang-Ping Hu; Xiao-Hong Zhang; Han-Wu Deng; Yuan-Jian Li
Lysophosphatidylcholine-induced elevation of asymmetric dimethylarginine level by the NADPH oxidase pathway in endothelial cells.
Vascular pharmacology 2006;44(3):143-8.
2005: Pan-Yue Deng; Jing Yu; Feng Ye; Dai Li; Dan Luo; Wei-Jun Cai; Jian-Wei Zhang; Xue-gang Luo; Han-Wu Deng; Yuan-Jian Li
Interactions of sympathetic nerves with capsaicin-sensitive sensory nerves: neurogenic mechanisms for phenol-induced hypertension in the rat.
Journal of hypertension 2005;23(3):603-9.
2005: Wei-Jie Peng; Jun-Lin Jiang; Su-Jie Jia; Dai Li; Xiao-Jie Zhang; Dan Luo; Er-Yuan Liao; Han-Wu Deng; Yuan-Jian Li
Asymmetric dimethylarginine is not involved in ovariectomy-induced osteopenia in rats.
Comparative medicine 2005;55(1):30-3.
2005: Wei Pan; L Darryl Quarles; Li-Hua Song; Yan-Hui Yu; Chen Jiao; Hong-Bo Tang; Chang-Hong Jiang; Han-Wu Deng; Yuan-Jian Li; Hong-Hao Zhou; Zhou-Sheng Xiao
Genistein stimulates the osteoblastic differentiation via NO/cGMP in bone marrow culture.
Journal of cellular biochemistry 2005;94(2):307-16.
2004: Wei-Qing Rang; Yan-Hua Du; Chang-Ping Hu; Feng Ye; Kang-Ping Xu; Jun Peng; Han-Wu Deng; Yuan-Jian Li
Protective effects of evodiamine on myocardial ischemia-reperfusion injury in rats.
Planta medica 2004;70(12):1140-3.
2004: Dan Luo; Pan-Yue Deng; Feng Ye; Wei-Jie Peng; Han-Wu Deng; Yuan-Jian Li
Delayed preconditioning by cardiac ischemia involves endogenous calcitonin gene-related peptide via the nitric oxide pathway.
European journal of pharmacology 2004;502(1-2):135-41.
2004: Zhong Dai; Duan-Fang Liao; De-Jian Jiang; Han-Wu Deng; Yuan-Jian Li
3,4,5,6-Tetrahydroxyxanthone prevents vascular endothelial cell apoptosis induced by high glucose.
Naunyn-Schmiedeberg's archives of pharmacology 2004;370(4):314-9.
2004: Yuan Zhou; Chang-Ping Hu; Pan-Yue Deng; Han-Wu Deng; Yuan-Jian Li
The protective effects of ligustrazine on ischemia-reperfusion and DPPH free radical-induced myocardial injury in isolated rat hearts.
Planta medica 2004;70(9):818-22.
2004: Pan-Yue Deng; Feng Ye; Wei-Jun Cai; Gui-Shan Tan; Chang-Ping Hu; Han-Wu Deng; Yuan-Jian Li
Stimulation of calcitonin gene-related peptide synthesis and release: mechanisms for a novel antihypertensive drug, rutaecarpine.
Journal of hypertension 2004;22(9):1819-29.
2004: Zhong Dai; Hui-Qing Zhu; De-Jian Jiang; Jun-Lin Jiang; Han-Wu Deng; Yuan-Jian Li
17beta-estradiol preserves endothelial function by reduction of the endogenous nitric oxide synthase inhibitor level.
International journal of cardiology 2004;96(2):223-7.
2004: Pan-Yue Deng; Feng Ye; Wei-Jun Cai; Han-Wu Deng; Yuan-Jian Li
Role of calcitonin gene-related peptide in the phenol-induced neurogenic hypertension in rats.
Regulatory peptides 2004;119(3):155-61.
2004: Jun-Lin Jiang; De-Jian Jiang; Yu-hai Tang; Nian-sheng Li; Han-Wu Deng; Yuan-Jian Li
Effect of simvastatin on endothelium-dependent vaso-relaxation and endogenous nitric oxide synthase inhibitor.
Acta pharmacologica Sinica 2004;25(7):893-901.
2004: Wei-Jie Peng; Jing Yu; Sheng Deng; Jun-Lin Jiang; Han-Wu Deng; Yuan-Jian Li
Effect of estrogen replacement treatment on ischemic preconditioning in isolated rat hearts.
Canadian journal of physiology and pharmacology 2004;82(5):339-44.
2004: Xu-Ping Qin; Feng Ye; Chang-Ping Hu; Duan-Fang Liao; Han-Wu Deng; Yuan-Jian Li
Effect of calcitonin gene-related peptide on angiotensin II-induced proliferation of rat vascular smooth muscle cells.
European journal of pharmacology 2004;488(1-3):45-9.
2004: Yan-Hua Du; Jun Peng; Zhi-Zhuang Huang; De-Jian Jiang; Han-Wu Deng; Yuan-Jian Li
Delayed cardioprotection afforded by nitroglycerin is mediated by alpha-CGRP via activation of inducible nitric oxide synthase.
International journal of cardiology 2004;93(1):49-54.
2003: De-Jian Jiang; Jun-Lin Jiang; Gui-Shan Tan; Zhi-Zhuang Huang; Han-Wu Deng; Yuan-Jian Li
Demethylbellidifolin inhibits adhesion of monocytes to endothelial cells via reduction of tumor necrosis factor alpha and endogenous nitric oxide synthase inhibitor level.
Planta medica 2003;69(12):1150-2.
2003: De-Jian Jiang; Gao-yun Hu; Jun-Lin Jiang; Hong-Lin Xiang; Han-Wu Deng; Yuan-Jian Li
Relationship between protective effect of xanthone on endothelial cells and endogenous nitric oxide synthase inhibitors.
Bioorganic & medicinal chemistry 2003;11(23):5171-7.
2003: Chang-Ping Hu; Nian-Sheng Li; Jun Peng; Liang Xiao; Han-Wu Deng; Yuan-Jian Li
Involvement of vanilloid receptors in heat stress-induced delayed protection against myocardial ischemia-reperfusion injury.
Neuropeptides 2003;37(4):233-8.
2003: Pan-Yue Deng; Feng Ye; Hui-Qing Zhu; Wei-Jun Cai; Han-Wu Deng; Yuan-Jian Li
An increase in the synthesis and release of calcitonin gene-related peptide in two-kidney, one-clip hypertensive rats.
Regulatory peptides 2003;114(2-3):175-82.
2003: Hui-Qing Zhu; Jun-Lin Jiang; Rong Lu; Xiao-Hong Zhang; Han-Wu Deng; Yuan-Jian Li
The protective effects of monophosphoryl lipid A on the ischemic myocardium and endothelium in rats.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 2003;17(4):311-8.
2003: Chang-Ping Hu; Nian-Sheng Li; Liang Xiao; Han-Wu Deng; Yuan-Jian Li
Involvement of capsaicin-sensitive sensory nerves in cardioprotection of rutaecarpine in rats.
Regulatory peptides 2003;114(1):45-9.
2003: Wei-Qing Rang; Yan-Hua Du; Chang-Ping Hu; Feng Ye; Gui-Shan Tan; Han-Wu Deng; Yuan-Jian Li
Protective effects of calcitonin gene-related peptide-mediated evodiamine on guinea-pig cardiac anaphylaxis.
Naunyn-Schmiedeberg's archives of pharmacology 2003;367(3):306-11.
2003: Chang-Ping Hu; Liang Xiao; Han-Wu Deng; Yuan-Jian Li
The depressor and vasodilator effects of rutaecarpine are mediated by calcitonin gene-related peptide.
Planta medica 2003;69(2):125-9.
2002: Chang-Ping Hu; Liang Xiao; Han-Wu Deng; Yuan-Jian Li
The cardioprotection of rutaecarpine is mediated by endogenous calcitonin related-gene peptide through activation of vanilloid receptors in guinea-pig hearts.
Planta medica 2002;68(8):705-9.
2002: Chang-Ping Hu; Jun Peng; Liang Xiao; Feng Ye; Han-Wu Deng; Yuan-Jian Li
Effect of age on alpha-calcitonin gene-related peptide-mediated delayed cardioprotection induced by intestinal preconditioning in rats.
Regulatory peptides 2002;107(1-3):137-43.
2002: Jun Peng; Rong Lu; Liang Xiao; Han-Wu Deng; Yuan-Jian Li
Involvement of alpha-calcitonin gene-related peptide in heat stress-induced delayed preconditioning in rat hearts.
Clinical and experimental pharmacology & physiology 2002;29(7):569-74.
2002: Zhi-Hong Zhou; Jun Peng; Feng Ye; Nian-Sheng Li; Han-Wu Deng; Yuan-Jian Li
Delayed cardioprotection induced by nitroglycerin is mediated by alpha-calcitonin gene-related peptide.
Naunyn-Schmiedeberg's archives of pharmacology 2002;365(4):253-9.
2002: Zhi-Hong Zhou; Jun-Lin Jiang; Jun Peng; Han-Wu Deng; Yuan-Jian Li
Reversal of tolerance to nitroglycerin with N-acetylcysteine or captopril: a role of calcitonin gene-related peptide.
European journal of pharmacology 2002;439(1-3):129-34.
2002: Jun-Lin Jiang; Nian-sheng Li Ns; Yuan-Jian Li; Han-Wu Deng
Probucol preserves endothelial function by reduction of the endogenous nitric oxide synthase inhibitor level.
British journal of pharmacology 2002;135(5):1175-82.
2002: Rong Lu; Jun Peng; Liang Xiao; Han-Wu Deng; Yuan-Jian Li
Heme oxygenase-1 pathway is involved in delayed protection induced by heat stress against cardiac ischemia-reperfusion injury.
International journal of cardiology 2002;82(2):133-40.
2002: Jun Peng; Rong Lu; Han-Wu Deng; Yuan-Jian Li
Involvement of alpha-calcitonin gene-related peptide in monophosphoryl lipid A-induced delayed preconditioning in rat hearts.
European journal of pharmacology 2002;436(1-2):89-96.
2002: Jun Peng; Rong Lu; Feng Ye; Han-Wu Deng; Yuan-Jian Li
The heme oxygenase-1 pathway is involved in calcitonin gene-related peptide-mediated delayed cardioprotection induced by monophosphoryl lipid A in rats.
Regulatory peptides 2002;103(1):1-7.
2002: Rong Ru; Jun Peng; Feng Ye; Han-Wu Deng; Yuan-Jian Li
Involvement of heme oxygenase-1 in delayed cardioprotection induced by monophosphoryl lipid A in rats.
Acta pharmacologica Sinica 2002;23(1):33-9.
2001: Zhou-Sheng Xiao; L Darryl Quarles; Qing-Quan Chen; Yan-Hui Yu; X P Qu; Chang-Hong Jiang; Han-Wu Deng; Yuan-Jian Li; Hong-Hao Zhou
Effect of asymmetric dimethylarginine on osteoblastic differentiation.
Kidney international 2001;60(5):1699-704.
2001: Jun Peng; Rong Lu; Feng Ye; Han-Wu Deng; Yuan-Jian Li
Induction of alpha-calcitonin gene-related peptide mRNA expression in rat dorsal root ganglia by heat stress involves the heme oxygenase-1/carbon monoxide pathway.
Neuropeptides 2001;35(5-6):297-302.
2001: Yan Xiong; L W Yuan; Han-Wu Deng; Yuan-Jian Li; Ben-Mei Chen
Elevated serum endogenous inhibitor of nitric oxide synthase and endothelial dysfunction in aged rats.
Clinical and experimental pharmacology & physiology 2001;28(10):842-7.
2001: B Tan; S Y He; Han-Wu Deng; Yuan-Jian Li
Role of calcitonin gene-related peptide in nitric oxide-mediated myocardial delayed preconditioning induced by head stress.
Acta pharmacologica Sinica 2001;22(9):851-6.