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Paul Denis

Research Profile

Chemicals & Drugs

Anatomy

Genes & Molecular Sequences

Amino Acid Sequences

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Banghua Sun; Wei Fan; Aldona Balciunas; Jillian K Cooper; Huiyuan Li; Shirley Steavenson; Paul E Denis; Yunjen Young; Beverly Adler; Larry Daugherty; Raffi Manoukian; Gary Elliott; Wenyan Shen; Jane Talvenheimo; David B Teplow; Mitsuru Haniu; Raj Haldankar; Jette Wypych; Christopher A Ross; Martin Citron; William G Richards
Polyglutamine repeat length-dependent proteolysis of huntingtin.
Y Luo; Brad Bolon; S Kahn; BD Bennett; Safura Babu-Khan; Paul E Denis; W Fan; H Kha; J Zhang; Y Gong; L Martin; Jean-Claude Louis; Q Yan; William G Richards; Martin Citron; Robert Vassar
Mice deficient in BACE1, the Alzheimer's beta-secretase, have normal phenotype and abolished beta-amyloid generation.
BD Bennett; Paul E Denis; Mitsuru Haniu; David B Teplow; S Kahn; Jean-Claude Louis; Martin Citron; Robert Vassar
A furin-like convertase mediates propeptide cleavage of BACE, the Alzheimer's beta -secretase.

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All Publications

2002: Banghua Sun; Wei Fan; Aldona Balciunas; Jillian K Cooper; Huiyuan Li; Shirley Steavenson; Paul E Denis; Yunjen Young; Beverly Adler; Larry Daugherty; Raffi Manoukian; Gary Elliott; Wenyan Shen; Jane Talvenheimo; David B Teplow; Mitsuru Haniu; Raj Haldankar; Jette Wypych; Christopher A Ross; Martin Citron; William G Richards
Polyglutamine repeat length-dependent proteolysis of huntingtin.
Neurobiology of disease 2002;11(1):111-22.
2001: Y Luo; Brad Bolon; S Kahn; BD Bennett; Safura Babu-Khan; Paul E Denis; W Fan; H Kha; J Zhang; Y Gong; L Martin; Jean-Claude Louis; Q Yan; William G Richards; Martin Citron; Robert Vassar
Mice deficient in BACE1, the Alzheimer's beta-secretase, have normal phenotype and abolished beta-amyloid generation.
Nature neuroscience 2001;4(3):231-2.
2000: BD Bennett; Paul E Denis; Mitsuru Haniu; David B Teplow; S Kahn; Jean-Claude Louis; Martin Citron; Robert Vassar
A furin-like convertase mediates propeptide cleavage of BACE, the Alzheimer's beta -secretase.
The Journal of biological chemistry 2000;275(48):37712-7.
2000: Mitsuru Haniu; Paul E Denis; Yunjen Young; E A Mendiaz; J Fuller; JO Hui; BD Bennett; S Kahn; S Ross; TL Burgess; V Katta; Gary A Rogers; Robert Vassar; Martin Citron
Characterization of Alzheimer's beta -secretase protein BACE. A pepsin family member with unusual properties.
The Journal of biological chemistry 2000;275(28):21099-106.
1999: Robert Vassar; BD Bennett; Safura Babu-Khan; S Kahn; E A Mendiaz; Paul E Denis; David B Teplow; S Ross; P Amarante; R Loeloff; Y Luo; S Fisher; J Fuller; S Edenson; Jack Lile; Mark Jarosinski; Anja Leona Biere; E Curran; TL Burgess; Jean-Claude Louis; F Collins; James J S Treanor; G Rogers; Martin Citron
Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE.
Science (New York, N.Y.) 1999;286(5440):735-41.
1999: Linda O Narhi; Stephen J Wood; Shirley Steavenson; Y Jiang; GM Wu; D Anafi; S A Kaufman; F Martin; K Sitney; Paul E Denis; Jean-Claude Louis; Jette Wypych; Anja Leona Biere; Martin Citron
Both familial Parkinson's disease mutations accelerate alpha-synuclein aggregation.
The Journal of biological chemistry 1999;274(14):9843-6.