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Helmut Denk

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Johannes Haybaeck; Michael Hesse; Thomas Kolbe; Thomas M Magin; Heimo Müller; Conny Stumptner; Andrea Thueringer; Michael Trauner; Oleksiy Tsybrovskyy; Kurt Zatloukal; Peter Fickert; Helmut Denk
Genetic background effects of keratin 8 and 18 in a DDC-induced hepatotoxicity and Mallory-Denk body formation mouse model.
Vineet Mahajan; K Peter R Nilsson; Rozalyn Simon; Andrea Thueringer; Peter M Abuja; Helmut Denk; Johannes Haybaeck; Karl Kashofer; Therése Klingstedt; Kurt Zatloukal
Cross β-sheet conformation of keratin 8 is a specific feature of Mallory-Denk bodies compared with other hepatocyte inclusions.
Helmut Denk
What is expected from the pathologist in the diagnosis of viral hepatitis?

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2012: Johannes Haybaeck; Michael Hesse; Thomas Kolbe; Thomas M Magin; Heimo Müller; Conny Stumptner; Andrea Thueringer; Michael Trauner; Oleksiy Tsybrovskyy; Kurt Zatloukal; Peter Fickert; Helmut Denk
Genetic background effects of keratin 8 and 18 in a DDC-induced hepatotoxicity and Mallory-Denk body formation mouse model.
Laboratory investigation; a journal of technical methods and pathology 2012;92(6):857-67.
2011: Vineet Mahajan; K Peter R Nilsson; Rozalyn Simon; Andrea Thueringer; Peter M Abuja; Helmut Denk; Johannes Haybaeck; Karl Kashofer; Therése Klingstedt; Kurt Zatloukal
Cross β-sheet conformation of keratin 8 is a specific feature of Mallory-Denk bodies compared with other hepatocyte inclusions.
Gastroenterology 2011;141(3):1080-1090.e1-7.
2011: Helmut Denk
What is expected from the pathologist in the diagnosis of viral hepatitis?
Virchows Archiv : an international journal of pathology 2011;458(4):377-92.
2010: Peter Fickert; Andrea Thueringer; Tarek Moustafa; Dagmar Silbert; Judith Gumhold; Oleksiy Tsybrovskyy; Margitta Lebofsky; Hartmut Jaeschke; Helmut Denk; Michael Trauner
The role of osteopontin and tumor necrosis factor alpha receptor-1 in xenobiotic-induced cholangitis and biliary fibrosis in mice.
Laboratory investigation; a journal of technical methods and pathology 2010;90(6):844-52.
2010: Andelko Hrzenjak; Farid Moinfar; Marie-Luise Kremser; Bettina Strohmeier; Edgar Petru; Kurt Zatloukal; Helmut Denk
Histone deacetylase inhibitor vorinostat suppresses the growth of uterine sarcomas in vitro and in vivo.
Molecular cancer 2010;9():49.
2009: Peter Fickert; Andrea Fuchsbichler; Tarek Moustafa; Martin Wagner; Gernot Zollner; Emina Halilbasic; Ulrike Stöger; Marco Arrese; Margarita Pizarro; Nancy Solís; Gonzalo Carrasco; Alessandra Caligiuri; Martina Sombetzki; Emil Reisinger; Oleksiy Tsybrovskyy; Kurt Zatloukal; Helmut Denk; Hartmut Jaeschke; Massimo Pinzani; Michael Trauner
Farnesoid X receptor critically determines the fibrotic response in mice but is expressed to a low extent in human hepatic stellate cells and periductal myofibroblasts.
The American journal of pathology 2009;175(6):2392-405.
2009: Peter Fickert; Andrea Fuchsbichler; Martin Wagner; Dagmar Silbert; Kurt Zatloukal; Helmut Denk; Michael Trauner
The role of the hepatocyte cytokeratin network in bile formation and resistance to bile acid challenge and cholestasis in mice.
Hepatology (Baltimore, Md.) 2009;50(3):893-9.
2009: Emina Halilbasic; Romina Fiorotto; Peter Fickert; Hanns-Ulrich Marschall; Tarek Moustafa; Carlo Spirlì; Andrea Fuchsbichler; Judith Gumhold; Dagmar Silbert; Kurt Zatloukal; Cord Langner; Uday Maitra; Helmut Denk; Alan F Hofmann; Mario Strazzabosco; Michael Trauner
Side chain structure determines unique physiologic and therapeutic properties of norursodeoxycholic acid in Mdr2-/- mice.
Hepatology (Baltimore, Md.) 2009;49(6):1972-81.
2009: Ariane Aigelsreiter; Elke Janig; Julia Sostaric; Martin Pichler; Daniela Unterthor; Judit Halasz; Carolin Lackner; Kurt Zatloukal; Helmut Denk
Clusterin expression in cholestasis, hepatocellular carcinoma and liver fibrosis.
Histopathology 2009;54(5):561-70.
2008: Andelko Hrzenjak; Marie-Luise Kremser; Bettina Strohmeier; Farid Moinfar; Kurt Zatloukal; Helmut Denk
SAHA induces caspase-independent, autophagic cell death of endometrial stromal sarcoma cells by influencing the mTOR pathway.
The Journal of pathology 2008;216(4):495-504.
2008: Carolin Lackner; Margit Gogg-Kamerer; Kurt Zatloukal; Conny Stumptner; Elizabeth M Brunt; Helmut Denk
Ballooned hepatocytes in steatohepatitis: the value of keratin immunohistochemistry for diagnosis.
Journal of hepatology 2008;48(5):821-8.
2007: Elke Janig; Martin Haslbeck; Ariane Aigelsreiter; Nathalie Braun; Daniela Unterthor; Peter Wolf; Noor Mohammad Khaskhely; Johannes Buchner; Helmut Denk; Kurt Zatloukal
Clusterin associates with altered elastic fibers in human photoaged skin and prevents elastin from ultraviolet-induced aggregation in vitro.
The American journal of pathology 2007;171(5):1474-82.
2007: Gernot Zollner; Martin Wagner; Peter Fickert; Dagmar Silbert; Judith Gumhold; Kurt Zatloukal; Helmut Denk; Michael Trauner
Expression of bile acid synthesis and detoxification enzymes and the alternative bile acid efflux pump MRP4 in patients with primary biliary cirrhosis.
Liver international : official journal of the International Association for the Study of the Liver 2007;27(7):920-9.
2007: Conny Stumptner; Andrea Fuchsbichler; Kurt Zatloukal; Helmut Denk
In vitro production of Mallory bodies and intracellular hyaline bodies: the central role of sequestosome 1/p62.
Hepatology (Baltimore, Md.) 2007;46(3):851-60.
2007: Martin Wagner; Gernot Zollner; Peter Fickert; Judith Gumhold; Dagmar Silbert; Andrea Fuchsbichler; Jaspreet S Gujral; Kurt Zatloukal; Helmut Denk; Hartmut Jaeschke; Michael Trauner
Hepatobiliary transporter expression in intercellular adhesion molecule 1 knockout and Fas receptor-deficient mice after common bile duct ligation is independent of the degree of inflammation and oxidative stress.
Drug metabolism and disposition: the biological fate of chemicals 2007;35(9):1694-9.
2007: Peter Fickert; Ulrike Stöger; Andrea Fuchsbichler; Tarek Moustafa; Hanns-Ulrich Marschall; Andreas H. Weiglein; Oleksiy Tsybrovskyy; Hartmut Jaeschke; Kurt Zatloukal; Helmut Denk; Michael Trauner
A new xenobiotic-induced mouse model of sclerosing cholangitis and biliary fibrosis.
The American journal of pathology 2007;171(2):525-36.
2007: Martin Asslaber; Peter Abuja; K Stark; J Eder; Herbert Gottweis; Michael Trauner; Hellmut Samonigg; Hans-Jörg Mischinger; Walter Schippinger; A Berghold; Helmut Denk; Kurt Zatloukal
The Genome Austria Tissue Bank (GATiB).
Pathobiology : journal of immunopathology, molecular and cellular biology 2007;74(4):251-8.
2007: Ariane Aigelsreiter; Elke Janig; Conny Stumptner; Andrea Fuchsbichler; Kurt Zatloukal; Helmut Denk
How a cell deals with abnormal proteins. Pathogenetic mechanisms in protein aggregation diseases.
Pathobiology : journal of immunopathology, molecular and cellular biology 2007;74(3):145-58.
2007: Erika Richtig; Andrea Berghold; Gerold Schwantzer; Arthur Ott; Friedrich Wölfelmaier; Beatrix Karner; Ralf Ludwig; Helmut Denk; Reinhold Stering; Gerhard Leitner; Sigurd F Lax; Murat Okcu; Armin Gerger; Helmut Kerl; Josef Smolle
Clinical epidemiology of invasive cutaneous malignant melanoma in the Austrian province Styria in the years 2001-2003 and its relationship with local geographical, meteorological and economic data.
Dermatology (Basel, Switzerland) 2007;214(3):246-52.
2007: Katrin Panzitt; Marisa M O Tschernatsch; Christian Guelly; Tarek Moustafa; Martin Stradner; Heimo M Strohmaier; Charles R Buck; Helmut Denk; Renée Schroeder; Michael Trauner; Kurt Zatloukal
Characterization of HULC, a novel gene with striking up-regulation in hepatocellular carcinoma, as noncoding RNA.
Gastroenterology 2007;132(1):330-42.
2006: Andelko Hrzenjak; Farid Moinfar; Marie-Luise Kremser; Bettina Strohmeier; Philipp B Staber; Kurt Zatloukal; Helmut Denk
Valproate inhibition of histone deacetylase 2 affects differentiation and decreases proliferation of endometrial stromal sarcoma cells.
Molecular cancer therapeutics 2006;5(9):2203-10.
2006: Gernot Zollner; Martin Wagner; Tarek Moustafa; Peter Fickert; Dagmar Silbert; Judith Gumhold; Andrea Fuchsbichler; Emina Halilbasic; Helmut Denk; Hanns-Ulrich Marschall; Michael Trauner
Coordinated induction of bile acid detoxification and alternative elimination in mice: role of FXR-regulated organic solute transporter-alpha/beta in the adaptive response to bile acids.
American journal of physiology. Gastrointestinal and liver physiology 2006;290(5):G923-32.
2006: Helmut Denk; Conny Stumptner; Andrea Fuchsbichler; T Müller; Gist Henry Farr; W Müller; L Terracciano; Kurt Zatloukal
Are the Mallory bodies and intracellular hyaline bodies in neoplastic and non-neoplastic hepatocytes related?
The Journal of pathology 2006;208(5):653-61.
2006: Sebastian Leibl; Koppany Bodo; Margit Gogg-Kammerer; Andelko Hrzenjak; Edgar Petru; Raimund Winter; Helmut Denk; Farid Moinfar
Ovarian granulosa cell tumors frequently express EGFR (Her-1), Her-3, and Her-4: An immunohistochemical study.
Gynecologic oncology 2006;101(1):18-23.
2006: Peter Fickert; Martin Wagner; Hanns-Ulrich Marschall; Andrea Fuchsbichler; Gernot Zollner; Oleksiy Tsybrovskyy; Kurt Zatloukal; Jie Liu; Michael P Waalkes; Cathleen Cover; Helmut Denk; Alan Hofmann; Hartmut Jaeschke; Michael Trauner
24-norUrsodeoxycholic acid is superior to ursodeoxycholic acid in the treatment of sclerosing cholangitis in Mdr2 (Abcb4) knockout mice.
Gastroenterology 2006;130(2):465-81.
2006: Peter Fickert; Andrea Fuchsbichler; Hanns-Ulrich Marschall; Martin Wagner; Gernot Zollner; Robert Krause; Kurt Zatloukal; Hartmut Jaeschke; Helmut Denk; Michael Trauner
Lithocholic acid feeding induces segmental bile duct obstruction and destructive cholangitis in mice.
The American journal of pathology 2006;168(2):410-22.
2005: Gernot Zollner; Martin Wagner; Peter Fickert; Andreas Geier; Andrea Fuchsbichler; Dagmar Silbert; Judith Gumhold; Kurt Zatloukal; Arthur Kaser; Herbert Tilg; Helmut Denk; Michael Trauner
Role of nuclear receptors and hepatocyte-enriched transcription factors for Ntcp repression in biliary obstruction in mouse liver.
American journal of physiology. Gastrointestinal and liver physiology 2005;289(5):G798-805.
2005: Andelko Hrzenjak; Farid Moinfar; Fattaneh A Tavassoli; Bettina Strohmeier; Marie-Luise Kremser; Kurt Zatloukal; Helmut Denk
JAZF1/JJAZ1 gene fusion in endometrial stromal sarcomas: molecular analysis by reverse transcriptase-polymerase chain reaction optimized for paraffin-embedded tissue.
The Journal of molecular diagnostics : JMD 2005;7(3):388-95.
2005: Martin Wagner; Emina Halilbasic; Hanns-Ulrich Marschall; Gernot Zollner; Peter Fickert; Cord Langner; Kurt Zatloukal; Helmut Denk; Michael Trauner
CAR and PXR agonists stimulate hepatic bile acid and bilirubin detoxification and elimination pathways in mice.
Hepatology (Baltimore, Md.) 2005;42(2):420-30.
2005: Carolin Lackner; Daniela Dlaska; Andrea Fuchsbichler; Conny Stumptner; Margit Gogg-Kamerer; Kurt Zatloukal; Helmut Denk
p62 protein is expressed in pancreatic beta cells.
The Journal of pathology 2005;206(4):402-8.
2005: Iris Halbwedl; Reinhard Ullmann; Marie-Luise Kremser; Yan-Gao Man; Narges Isadi-Moud; Sigurd F Lax; Helmut Denk; Helmut H Popper; Fattaneh A Tavassoli; Farid Moinfar
Chromosomal alterations in low-grade endometrial stromal sarcoma and undifferentiated endometrial sarcoma as detected by comparative genomic hybridization.
Gynecologic oncology 2005;97(2):582-7.
2005: Gernot Zollner; Martin Wagner; Peter Fickert; Dagmar Silbert; Andrea Fuchsbichler; Kurt Zatloukal; Helmut Denk; Michael Trauner
Hepatobiliary transporter expression in human hepatocellular carcinoma.
Liver international : official journal of the International Association for the Study of the Liver 2005;25(2):367-79.
2005: Farid Moinfar; Margit Gogg-Kamerer; Andrea Sommersacher; Peter Regitnig; Yan-Gao Man; Kurt Zatloukal; Helmut Denk; Fattaneh A Tavassoli
Endometrial stromal sarcomas frequently express epidermal growth factor receptor (EGFR, HER-1): potential basis for a new therapeutic approach.
The American journal of surgical pathology 2005;29(4):485-9.
2005: Elke Janig; Conny Stumptner; Andrea Fuchsbichler; Helmut Denk; Kurt Zatloukal
Interaction of stress proteins with misfolded keratins.
European journal of cell biology 2005;84(2-3):329-39.
2005: Sebastian Leibl; Margit Gogg-Kammerer; Andrea Sommersacher; Helmut Denk; Farid Moinfar
Metaplastic breast carcinomas: are they of myoepithelial differentiation?: immunohistochemical profile of the sarcomatoid subtype using novel myoepithelial markers.
The American journal of surgical pathology 2005;29(3):347-53.
2005: Andreas Geier; Gernot Zollner; Christoph G Dietrich; Martin Wagner; Peter Fickert; Helmut Denk; Nico van Rooijen; Siegfried Matern; Carsten Gartung; Michael Trauner
Cytokine-independent repression of rodent Ntcp in obstructive cholestasis.
Hepatology (Baltimore, Md.) 2005;41(3):470-7.
2005: Peter Fickert; Michael Trauner; Andrea Fuchsbichler; Gernot Zollner; Martin Wagner; Hanns-Ulrich Marschall; Kurt Zatloukal; Helmut Denk
Oncosis represents the main type of cell death in mouse models of cholestasis.
Journal of hepatology 2005;42(3):378-85.
2005: Helmut Denk; Conny Stumptner; Andrea Fuchsbichler; Kurt Zatloukal
[Alcoholic and non-alcoholic steatohepatitis].
Verhandlungen der Deutschen Gesellschaft für Pathologie 2005;89():137-43.
2004: Farid Moinfar; Marie-Luise Kremser; Yan-Gao Man; Kurt Zatloukal; Fattaneh A Tavassoli; Helmut Denk
Allelic imbalances in endometrial stromal neoplasms: frequent genetic alterations in the nontumorous normal-appearing endometrial and myometrial tissues.
Gynecologic oncology 2004;95(3):662-71.
2004: Kurt Zatloukal; Conny Stumptner; Andrea Fuchsbichler; Peter Fickert; Carolin Lackner; Michael Trauner; Helmut Denk
The keratin cytoskeleton in liver diseases.
The Journal of pathology 2004;204(4):367-76.
2004: Andelko Hrzenjak; Michaela Tippl; Marie-Luise Kremser; Bettina Strohmeier; Christian Guelly; Doris Neumeister; Sigurd F Lax; Farid Moinfar; Ali Dastranj Tabrizi; Narges Isadi-Moud; Kurt Zatloukal; Helmut Denk
Inverse correlation of secreted frizzled-related protein 4 and beta-catenin expression in endometrial stromal sarcomas.
The Journal of pathology 2004;204(1):19-27.
2004: Carolin Lackner; Z Jukic; Oleksiy Tsybrovskyy; Gerlinde Jatzko; Viktor Wette; Gerald Hoefler; Martin Klimpfinger; Helmut Denk; Kurt Zatloukal
Prognostic relevance of tumour-associated macrophages and von Willebrand factor-positive microvessels in colorectal cancer.
Virchows Archiv : an international journal of pathology 2004;445(2):160-7.
2004: Cord Langner; Helmut Denk
Wilson disease.
Virchows Archiv : an international journal of pathology 2004;445(2):111-8.
2004: Peter Fickert; Andrea Fuchsbichler; Martin Wagner; Gernot Zollner; Arthur Kaser; Herbert Tilg; Robert Krause; Frank Lammert; Cord Langner; Kurt Zatloukal; Hanns-Ulrich Marschall; Helmut Denk; Michael Trauner
Regurgitation of bile acids from leaky bile ducts causes sclerosing cholangitis in Mdr2 (Abcb4) knockout mice.
Gastroenterology 2004;127(1):261-74.
2004: Farid Moinfar; Peter Regitnig; Ali Dastranj Tabrizi; Helmut Denk; Fattaneh A Tavassoli
Expression of androgen receptors in benign and malignant endometrial stromal neoplasms.
Virchows Archiv : an international journal of pathology 2004;444(5):410-4.
2004: Thomas Müller; Cord Langner; Andrea Fuchsbichler; Peter Heinz-Erian; Helmut Ellemunter; Barbara Schlenck; Ashish Bavdekar; Avinash M Pradhan; Anand Pandit; Josef Müller-Höcker; Michael Melter; Kunihiko Kobayashi; Hironori Nagasaka; Hideaki Kikuta; Wilfried Müller; M Stuart Tanner; Irmin Sternlieb; Kurt Zatloukal; Helmut Denk
Immunohistochemical analysis of Mallory bodies in Wilsonian and non-Wilsonian hepatic copper toxicosis.
Hepatology (Baltimore, Md.) 2004;39(4):963-9.
2004: Kurt Zatloukal; Conny Stumptner; Andrea Fuchsbichler; Elke Janig; Helmut Denk
Intermediate filament protein inclusions.
Methods in cell biology 2004;78():205-28.
2003: Gernot Zollner; Peter Fickert; Andrea Fuchsbichler; Dagmar Silbert; Martin Wagner; Silvia Arbeiter; Frank J Gonzalez; Hanns-Ulrich Marschall; Kurt Zatloukal; Helmut Denk; Michael Trauner
Role of nuclear bile acid receptor, FXR, in adaptive ABC transporter regulation by cholic and ursodeoxycholic acid in mouse liver, kidney and intestine.
Journal of hepatology 2003;39(4):480-8.
2003: Martin Wagner; Peter Fickert; Gernot Zollner; Andrea Fuchsbichler; Dagmar Silbert; Oleksiy Tsybrovskyy; Kurt Zatloukal; Grace L Guo; John D Schuetz; Frank J Gonzalez; Hanns-Ulrich Marschall; Helmut Denk; Michael Trauner
Role of farnesoid X receptor in determining hepatic ABC transporter expression and liver injury in bile duct-ligated mice.
Gastroenterology 2003;125(3):825-38.
2003: Farid Moinfar; Murat Okcu; Oleksiy Tsybrovskyy; Peter Regitnig; Sigurd F Lax; Wolfgang Weybora; Manfred Ratschek; Fattaneh A Tavassoli; Helmut Denk
Androgen receptors frequently are expressed in breast carcinomas: potential relevance to new therapeutic strategies.
Cancer 2003;98(4):703-11.
2003: Sebastian Leibl; Oleksiy Tsybrovskyy; Helmut Denk
How many lymph nodes are necessary to stage early and advanced adenocarcinoma of the sigmoid colon and upper rectum?
Virchows Archiv : an international journal of pathology 2003;443(2):133-8.
2003: Gernot Zollner; Peter Fickert; Dagmar Silbert; Andrea Fuchsbichler; Hanns-Ulrich Marschall; Kurt Zatloukal; Helmut Denk; Michael Trauner
Adaptive changes in hepatobiliary transporter expression in primary biliary cirrhosis.
Journal of hepatology 2003;38(6):717-27.
2003: Peter Fickert; Michael Trauner; Andrea Fuchsbichler; Conny Stumptner; Kurt Zatloukal; Helmut Denk
Mallory body formation in primary biliary cirrhosis is associated with increased amounts and abnormal phosphorylation and ubiquitination of cytokeratins.
Journal of hepatology 2003;38(4):387-94.
2003: Thomas Müller; Bart van De Sluis; Alexandra Zhernakova; Ellen van Binsbergen; Andreas R Janecke; Ashish Bavdekar; Anand Pandit; Helga Weirich-Schwaiger; Heiko Witt; Helmut Ellemunter; Johann Deutsch; Helmut Denk; Wilfried Müller; Irmin Sternlieb; M Stuart Tanner; Cisca Wijmenga
The canine copper toxicosis gene MURR1 does not cause non-Wilsonian hepatic copper toxicosis.
Journal of hepatology 2003;38(2):164-8.
2002: Peter Fickert; Michael Trauner; Andrea Fuchsbichler; Conny Stumptner; Kurt Zatloukal; Helmut Denk
Bile acid-induced Mallory body formation in drug-primed mouse liver.
The American journal of pathology 2002;161(6):2019-26.
2002: Peter Fickert; Gernot Zollner; Andrea Fuchsbichler; Conny Stumptner; Andreas H. Weiglein; Frank Lammert; Hanns-Ulrich Marschall; Oleksiy Tsybrovskyy; Kurt Zatloukal; Helmut Denk; Michael Trauner
Ursodeoxycholic acid aggravates bile infarcts in bile duct-ligated and Mdr2 knockout mice via disruption of cholangioles.
Gastroenterology 2002;123(4):1238-51.
2002: Conny Stumptner; Andrea Fuchsbichler; Hans Heid; Kurt Zatloukal; Helmut Denk
Mallory body--a disease-associated type of sequestosome.
Hepatology (Baltimore, Md.) 2002;35(5):1053-62.
2002: Peter Fickert; Michael Trauner; Andrea Fuchsbichler; Conny Stumptner; Kurt Zatloukal; Helmut Denk
Cytokeratins as targets for bile acid-induced toxicity.
The American journal of pathology 2002;160(2):491-9.
2002: Kurt Zatloukal; Conny Stumptner; Andrea Fuchsbichler; Hans Heid; Martina Schnoelzer; Lukas Kenner; Reinhold Kleinert; Marco Prinz; Adriano Aguzzi; Helmut Denk
p62 Is a common component of cytoplasmic inclusions in protein aggregation diseases.
The American journal of pathology 2002;160(1):255-63.
2002: Gernot Zollner; Peter Fickert; Dagmar Silbert; Andrea Fuchsbichler; Conny Stumptner; Kurt Zatloukal; Helmut Denk; Michael Trauner
Induction of short heterodimer partner 1 precedes downregulation of Ntcp in bile duct-ligated mice.
American journal of physiology. Gastrointestinal and liver physiology 2002;282(1):G184-91.
2001: Helmut Denk; Conny Stumptner; Andrea Fuchsbichler; Kurt Zatloukal
[Alcoholic and nonalcoholic steatohepatitis. Histopathologic and pathogenetic considerations].
Der Pathologe 2001;22(6):388-98.
2001: Cord Langner; Helmut Denk
[Chronic cholangitis].
Der Pathologe 2001;22(6):375-87.
2001: Peter Fickert; Gernot Zollner; Andrea Fuchsbichler; Conny Stumptner; C Pojer; Rainer Zenz; F Lammert; B Stieger; Peter Meier; Kurt Zatloukal; Helmut Denk; Michael Trauner
Effects of ursodeoxycholic and cholic acid feeding on hepatocellular transporter expression in mouse liver.
Gastroenterology 2001;121(1):170-83.
2001: Peter Regitnig; E Spuller; Helmut Denk
Insulinoma of the pancreas with insular-ductular differentiation in its liver metastasis--indication of a common stem-cell origin of the exocrine and endocrine components.
Virchows Archiv : an international journal of pathology 2001;438(6):624-8.
2001: Conny Stumptner; Andrea Fuchsbichler; M Lehner; Kurt Zatloukal; Helmut Denk
Sequence of events in the assembly of Mallory body components in mouse liver: clues to the pathogenesis and significance of Mallory body formation.
Journal of hepatology 2001;34(5):665-75.
2001: Gernot Zollner; Peter Fickert; Rainer Zenz; Andrea Fuchsbichler; Conny Stumptner; Lukas Kenner; Peter Ferenci; Rudolf E Stauber; Günter J Krejs; Helmut Denk; Kurt Zatloukal; Michael Trauner
Hepatobiliary transporter expression in percutaneous liver biopsies of patients with cholestatic liver diseases.
Hepatology (Baltimore, Md.) 2001;33(3):633-46.
2000: Peter Regitnig; Helmut Denk
Lack of Pseudomelanosis coli in colonic adenomas suggests different pathways of apoptotic bodies in normal and neoplastic colonic mucosa.
Virchows Archiv : an international journal of pathology 2000;436(6):588-94.
2000: Helmut Denk; Conny Stumptner; Kurt Zatloukal
Mallory bodies revisited.
Journal of hepatology 2000;32(4):689-702.
2000: Kurt Zatloukal; Conny Stumptner; M Lehner; Helmut Denk; H Baribault; Leonid Eshkind; W W Franke
Cytokeratin 8 protects from hepatotoxicity, and its ratio to cytokeratin 18 determines the ability of hepatocytes to form Mallory bodies.
The American journal of pathology 2000;156(4):1263-74.
2000: Conny Stumptner; Bishr Omary; Peter Fickert; Helmut Denk; Kurt Zatloukal
Hepatocyte cytokeratins are hyperphosphorylated at multiple sites in human alcoholic hepatitis and in a mallory body mouse model.
The American journal of pathology 2000;156(1):77-90.
1999: Conny Stumptner; Hans Heid; Andrea Fuchsbichler; H Hauser; Hans-Jörg Mischinger; Kurt Zatloukal; Helmut Denk
Analysis of intracytoplasmic hyaline bodies in a hepatocellular carcinoma. Demonstration of p62 as major constituent.
The American journal of pathology 1999;154(6):1701-10.
1999: Lukas Kenner; Kurt Zatloukal; Conny Stumptner; Robert Eferl; Helmut Denk
Altered microtubule-associated tau messenger RNA isoform expression in livers of griseofulvin- and 3,5-diethoxycarbonyl-1, 4-dihydrocollidine-treated mice.
Hepatology (Baltimore, Md.) 1999;29(3):793-800.
1999: K H Preisegger; Valentina M Factor; Andrea Fuchsbichler; Conny Stumptner; Helmut Denk; Snorri S Thorgeirsson
Atypical ductular proliferation and its inhibition by transforming growth factor beta1 in the 3,5-diethoxycarbonyl-1,4-dihydrocollidine mouse model for chronic alcoholic liver disease.
Laboratory investigation; a journal of technical methods and pathology 1999;79(2):103-9.
1999: Conny Stumptner; Hans Heid; Kurt Zatloukal; Andrea Fuchsbichler; H Hauser; Helmut Denk
Identification of p62, a phosphotyrosine independent ligand of p56lck kinase, as a major component of intracytoplasmic hyaline bodies in hepatocellular carcinoma.
Verhandlungen der Deutschen Gesellschaft für Pathologie 1999;83():254-9.
1996: K H Preisegger; Conny Stumptner; D Riegelnegg; P C Brown; J A Silverman; Snorri S Thorgeirsson; Helmut Denk
Experimental Mallory body formation is accompanied by modulation of the expression of multidrug-resistance genes and their products.
Hepatology (Baltimore, Md.) 1996;24(1):248-52.
1995: Kurt Zatloukal; Lukas Kenner; K H Preisegger; Helmut Denk
Alcoholic liver disease: molecular-pathologic aspects.
Verhandlungen der Deutschen Gesellschaft für Pathologie 1995;79():28-35.
1995: Helmut Denk
[Chronic hepatitis].
Verhandlungen der Deutschen Gesellschaft für Pathologie 1995;79():171-6.
1994: Lukas Kenner; Yosuf El Shabrawi; H Hutter; M Forstner; Kurt Zatloukal; Gerald Hoefler; K H Preisegger; R Kurzbauer; Helmut Denk
Expression of three- and four-repeat tau isoforms in mouse liver.
Hepatology (Baltimore, Md.) 1994;20(4 Pt 1):1086-9.
1994: H Salmhofer; Irmgard Rainer; Kurt Zatloukal; Helmut Denk
Posttranslational events involved in griseofulvin-induced keratin cytoskeleton alterations.
Hepatology (Baltimore, Md.) 1994;20(3):731-40.
1994: Helmut Denk
[Molecular pathology: fashion? Necessity?].
Verhandlungen der Deutschen Gesellschaft für Pathologie 1994;78():1-7.
1993: H Hutter; Kurt Zatloukal; G Winter; Conny Stumptner; Helmut Denk
Disturbance of keratin homeostasis in griseofulvin-intoxicated mouse liver.
Laboratory investigation; a journal of technical methods and pathology 1993;69(5):576-82.
1993: W Ohlinger; H P Dinges; Kurt Zatloukal; S Mair; F Gollowitsch; Helmut Denk
Immunohistochemical detection of tumor necrosis factor-alpha, other cytokines and adhesion molecules in human livers with alcoholic hepatitis.
Virchows Archiv. A, Pathological anatomy and histopathology 1993;423(3):169-76.
1993: C Schmid; Kurt Zatloukal; Alfred Beham; Helmut Denk
Involucrin expression in breast carcinomas: an immunohistochemical study.
Virchows Archiv. A, Pathological anatomy and histopathology 1993;423(3):161-7.
1992: H P Dinges; Kurt Zatloukal; Helmut Denk; J Smolle; S Mair
Alcoholic liver disease. Parenchyma to stroma relationship in fibrosis and cirrhosis as revealed by three-dimensional reconstruction and immunohistochemistry.
The American journal of pathology 1992;141(1):69-83.
1992: Kurt Zatloukal; Laszlo Fesus; Helmut Denk; E Tarcsa; G Spurej; G Böck
High amount of epsilon-(gamma-glutamyl)lysine cross-links in Mallory bodies.
Laboratory investigation; a journal of technical methods and pathology 1992;66(6):774-7.
1992: Kurt Zatloukal; Helmut Denk; G Spurej; H Hutter
Modulation of protein composition of nuclear lamina. Reduction of lamins B1 and B2 in livers of griseofulvin-treated mice.
Laboratory investigation; a journal of technical methods and pathology 1992;66(5):589-97.
1992: K H Preisegger; Kurt Zatloukal; G Spurej; D Riegelnegg; Helmut Denk
Common epitopes of human and murine Mallory bodies and Lewy bodies as revealed by a neurofilament antibody.
Laboratory investigation; a journal of technical methods and pathology 1992;66(2):193-9.
1992: Alfred Beham; M Ratschek; Kurt Zatloukal; C Schmid; Helmut Denk
Distribution of cytokeratins, vimentin and desmoplakins in normal renal tissue, renal cell carcinomas and oncocytoma as revealed by immunofluorescence microscopy.
Virchows Archiv. A, Pathological anatomy and histopathology 1992;421(3):209-15.
1992: Helmut Denk
[Pathology in Graz].
Verhandlungen der Deutschen Gesellschaft für Pathologie 1992;76():XXX-XXXVII.
1991: K H Preisegger; Kurt Zatloukal; G Spurej; Helmut Denk
Changes of cytokeratin filament organization in human and murine Mallory body-containing livers as revealed by a panel of monoclonal antibodies.
Liver 1991;11(5):300-9.
1991: M Woltsche; Kurt Zatloukal; Helmut Denk
Enzyme-histochemical studies of griseofulvin-intoxicated mouse livers.
Liver 1991;11(4):231-40.
1991: Kurt Zatloukal; G Böck; Irmgard Rainer; Helmut Denk; K Weber
High molecular weight components are main constituents of Mallory bodies isolated with a fluorescence activated cell sorter.
Laboratory investigation; a journal of technical methods and pathology 1991;64(2):200-6.
1990: Herbert Radner; R Kleinert; F Vennigerholz; Helmut Denk
Peculiar changes in Rosenthal fibres in an atypical astrocytoma.
Neuropathology and applied neurobiology 1990;16(2):171-7.
1990: Kurt Zatloukal; Helmut Denk; G Spurej; E Lackinger; K H Preisegger; W W Franke
High molecular weight component of Mallory bodies detected by a monoclonal antibody.
Laboratory investigation; a journal of technical methods and pathology 1990;62(4):427-34.
1990: Kurt Zatloukal; G Spurej; Irmgard Rainer; E Lackinger; Helmut Denk
Fate of Mallory body-containing hepatocytes: disappearance of Mallory bodies and restoration of the hepatocytic intermediate filament cytoskeleton after drug withdrawal in the griseofulvin-treated mouse.
Hepatology (Baltimore, Md.) 1990;11(4):652-61.
1990: Helmut Denk; Kurt Zatloukal; K H Preisegger
[Cytoskeleton--function and pathology: studies on the pathology of the intermediate filament cytoskeleton of liver cells].
Verhandlungen der Deutschen Gesellschaft für Pathologie 1990;74():335-49.
1989: Kurt Zatloukal; Helmut Denk; E Lackinger; Irmgard Rainer
Hepatocellular cytokeratins as substrates of transglutaminases.
Laboratory investigation; a journal of technical methods and pathology 1989;61(6):603-8.
1989: Helmut Denk; Kurt Zatloukal; K Preisegger
Ubiquitin--a common denominator in intermediate filament pathology of brain and liver?
Hepatology (Baltimore, Md.) 1989;10(4):514-5.
1989: Alfred Beham; M Ratschek; Kurt Zatloukal; Helmut Denk; E Lackinger
[Immunohistochemical analysis of 42 renal cell carcinomas and one oncocytoma with mono- and polyclonal antibodies against vimentin and cytokeratin].
Verhandlungen der Deutschen Gesellschaft für Pathologie 1989;73():392-5.
1988: Alfred Beham; Helmut Denk; Gernot Desoye
The distribution of intermediate filament proteins, actin and desmoplakins in human placental tissue as revealed by polyclonal and monoclonal antibodies.
Placenta 1988;9(5):479-92.
1988: Kurt Zatloukal; R Sohar; E Lackinger; Helmut Denk
Induction of heat shock proteins in short-term cultured hepatocytes derived from normal and chronically griseofulvin-treated mice.
Hepatology (Baltimore, Md.) 1988;8(3):607-12.
1987: Helmut Denk; E Lackinger; Kurt Zatloukal; W W Franke
Turnover of cytokeratin polypeptides in mouse hepatocytes.
Experimental cell research 1987;173(1):137-43.
1987: Helmut Denk; R Moll; W Weybora; E Lackinger; F Vennigerholz; Alfred Beham; W W Franke
Intermediate filaments and desmosomal plaque proteins in testicular seminomas and non-seminomatous germ cell tumours as revealed by immunohistochemistry.
Virchows Archiv. A, Pathological anatomy and histopathology 1987;410(4):295-307.
1986: Alfred Beham; W Weybora; E Lackinger; Helmut Denk; V Björklund; B Björklund
Distribution of TPA and cytokeratins in gastrointestinal carcinomas as revealed by immunohistochemistry.
Virchows Archiv. A, Pathological anatomy and histopathology 1986;409(5):641-55.
1986: Helmut Denk; E Lackinger; F Vennigerholz
Pathology of the cytoskeleton of hepatocytes.
Progress in liver diseases 1986;8():237-51.