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Joachim Denner

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TOP 3
Michael Mühle; Kerstin Hoffmann; Martin Löchelt; Joachim Denner
Immunisation with foamy virus Bet fusion proteins as novel strategy for HIV-1 epitope delivery.
Alexander Waechter; Magdalena Eschricht; Joachim Denner
Neutralization of porcine endogenous retrovirus by antibodies against the membrane-proximal external region of the transmembrane envelope protein.
Danny Kaulitz; Debora Mihica; Marwan Semaan; Cornelia Adlhoch; Joachim Denner
Improved pig donor screening including newly identified variants of porcine endogenous retrovirus-C (PERV-C).

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All Publications

2013: Michael Mühle; Kerstin Hoffmann; Martin Löchelt; Joachim Denner
Immunisation with foamy virus Bet fusion proteins as novel strategy for HIV-1 epitope delivery.
Immunologic research 2013;56(1):61-72.
2013: Alexander Waechter; Magdalena Eschricht; Joachim Denner
Neutralization of porcine endogenous retrovirus by antibodies against the membrane-proximal external region of the transmembrane envelope protein.
The Journal of general virology 2013;94(Pt 3):643-51.
2013: Danny Kaulitz; Debora Mihica; Marwan Semaan; Cornelia Adlhoch; Joachim Denner
Improved pig donor screening including newly identified variants of porcine endogenous retrovirus-C (PERV-C).
Archives of virology 2013;158(2):341-8.
2013: Joachim Denner; Magdalena Eschricht; Michael Lauck; Hyunmi Ryu; Philipp Schlaermann; Marwan Semaan; Levent Akyüz
Modulation of cytokine release and gene expression by the immunosuppressive domain of gp41 of HIV-1.
PloS one 2013;8(1):e55199.
2012: Iris Bittmann; Debora Mihica; Roland Plesker; Joachim Denner
Expression of porcine endogenous retroviruses (PERV) in different organs of a pig.
Virology 2012;433(2):329-36.
2012: Marwan Semaan; Danny Kaulitz; Heiner Niemann; Björn Petersen; Joachim Denner
Long-term effects of PERV-specific RNA interference in transgenic pigs.
Xenotransplantation 2012;19(2):112-21.
2012: Joachim Denner; Danny Kaulitz; Debora Mihica; Christa-Maria Schmidt
Increased titers of neutralizing antibodies after immunization with both envelope proteins of the porcine endogenous retroviruses (PERVs).
Virology journal 2012;9():260.
2012: Vladimir A Morozov; Marwan Semaan; Alexey V Morozov; Joachim Denner
Single mutations in the transmembrane envelope protein abrogate the immunosuppressive property of HIV-1.
Retrovirology 2012;9():67.
2012: Michael Mühle; Martin Löchelt; Joachim Denner
Optimisation of expression and purification of the feline and primate foamy virus transmembrane envelope proteins using a 96 deep well screen.
Protein expression and purification 2012;81(1):96-105.
2012: R Behrendt; Uwe Fiebig; Reinhard Kurth; Joachim Denner
Induction of antibodies binding to the membrane proximal external region of gp36 of HIV-2.
Intervirology 2012;55(3):252-6.
2011: Danny Kaulitz; Debora Mihica; Heiner Niemann; Björn Petersen; Ralf R Tönjes; Michael Rodrigues Costa; Jens Dorna; Joachim Denner
Development of sensitive methods for detection of porcine endogenous retrovirus-C (PERV-C) in the genome of pigs.
Journal of virological methods 2011;175(1):60-5.
2011: Joachim Denner
Infectious risk in xenotransplantation--what post-transplant screening for the human recipient?
Xenotransplantation 2011;18(3):151-7.
2011: Michael Mühle; Anne Bleiholder; Susanne Kolb; Janine Hübner; Martin Löchelt; Joachim Denner
Immunological properties of the transmembrane envelope protein of the feline foamy virus and its use for serological screening.
Virology 2011;412(2):333-40.
2011: D Kaulitz; D Mihica; Roland Plesker; A Geissler; Ralf R Tönjes; Joachim Denner
Absence of infection in pigs inoculated with high-titre recombinant PERV-A/C.
Archives of virology 2011;156(4):707-10.
2011: Danny Kaulitz; Uwe Fiebig; Magdalena Eschricht; Christian Wurzbacher; Reinhard Kurth; Joachim Denner
Generation of neutralising antibodies against porcine endogenous retroviruses (PERVs).
Virology 2011;411(1):78-86.
2011: Stefan Langhammer; Uwe Fiebig; Reinhard Kurth; Joachim Denner
Increased neutralizing antibody response after simultaneous immunization with leucogen and the feline leukemia virus transmembrane protein.
Intervirology 2011;54(2):78-86.
2011: Joachim Denner
Towards an AIDS vaccine: the transmembrane envelope protein as target for broadly neutralizing antibodies.
Human vaccines 2011;7 Suppl():4-9.
2011: Stefan Langhammer; Janine Hübner; Oswald Jarrett; Reinhard Kurth; Joachim Denner
Immunization with the transmembrane protein of a retrovirus, feline leukemia virus: absence of antigenemia following challenge.
Antiviral research 2011;89(1):119-23.
2010: Sven Stengel; Uwe Fiebig; Reinhard Kurth; Joachim Denner
Regulation of human endogenous retrovirus-K expression in melanomas by CpG methylation.
Genes, chromosomes & cancer 2010;49(5):401-11.
2010: Alexander Karlas; Markus Irgang; Jörg Votteler; Volker Specke; Muhsin Ozel; Reinhard Kurth; Joachim Denner
Characterisation of a human cell-adapted porcine endogenous retrovirus PERV-A/C.
Annals of transplantation : quarterly of the Polish Transplantation Society 2010;15(2):45-54.
2010: Joachim Denner
Detection of a gammaretrovirus, XMRV, in the human population: open questions and implications for xenotransplantation.
Retrovirology 2010;7():16.
2009: Joachim Denner; Henk-Jan Schuurman; Clive Patience
The International Xenotransplantation Association consensus statement on conditions for undertaking clinical trials of porcine islet products in type 1 diabetes--chapter 5: Strategies to prevent transmission of porcine endogenous retroviruses.
Xenotransplantation 2009;16(4):239-48.
2009: R Behrendt; Uwe Fiebig; Stephen Norley; L Gürtler; Reinhard Kurth; Joachim Denner
A neutralization assay for HIV-2 based on measurement of provirus integration by duplex real-time PCR.
Journal of virological methods 2009;159(1):40-6.
2009: Uwe Fiebig; Mirco Schmolke; Magdalena Eschricht; Reinhard Kurth; Joachim Denner
Mode of interaction between the HIV-1-neutralizing monoclonal antibody 2F5 and its epitope.
AIDS (London, England) 2009;23(8):887-95.
2009: Britta Dieckhoff; Barbara Kessler; Danny Jobst; Wilfried Kues; Björn Petersen; Alexander Pfeifer; Reinhard Kurth; Heiner Niemann; Eckhard Wolf; Joachim Denner
Distribution and expression of porcine endogenous retroviruses in multi-transgenic pigs generated for xenotransplantation.
Xenotransplantation 2009;16(2):64-73.
2009: Oliver Hohn; Hans Krause; Pia Barbarotto; Lars Niederstadt; Nadine Beimforde; Joachim Denner; Kurt Miller; Reinhard Kurth; Norbert Bannert
Lack of evidence for xenotropic murine leukemia virus-related virus(XMRV) in German prostate cancer patients.
Retrovirology 2009;6():92.
2009: Volker Specke; Roland Plesker; James Wood; Cheick Coulibaly; Kristen Suling; Clive Patience; Reinhard Kurth; Henk-Jan Schuurman; Joachim Denner
No in vivo infection of triple immunosuppressed non-human primates after inoculation with high titers of porcine endogenous retroviruses.
Xenotransplantation 2009;16(1):34-44.
2008: Joachim Denner
Is porcine endogenous retrovirus (PERV) transmission still relevant?
Transplantation proceedings 2008;40(2):587-9.
2008: Britta Dieckhoff; Björn Petersen; Wilfried Kues; Reinhard Kurth; Heiner Niemann; Joachim Denner
Knockdown of porcine endogenous retrovirus (PERV) expression by PERV-specific shRNA in transgenic pigs.
Xenotransplantation 2008;15(1):36-45.
2008: Markus Irgang; Christine Laue; Florian Velten; Reinhard Kurth; Jürgen Schrezenmeier; Joachim Denner
No evidence for PERV release by islet cells from German landrace pigs.
Annals of transplantation : quarterly of the Polish Transplantation Society 2008;13(4):59-66.
2008: Joachim Denner
Recombinant porcine endogenous retroviruses (PERV-A/C): a new risk for xenotransplantation?
Archives of virology 2008;153(8):1421-6.
2008: Joachim Denner; Volker Specke; Alexander Karlas; Irina Chodnevskaja; Thomas Meyer; Vasiliy Moskalenko; Reinhard Kurth; Karin Ulrichs
No transmission of porcine endogenous retroviruses (PERVs) in a long-term pig to rat xenotransplantation model and no infection of immunosuppressed rats.
Annals of transplantation : quarterly of the Polish Transplantation Society 2008;13(1):20-31.
2007: Joachim Denner
Transspecies transmissions of retroviruses: new cases.
Virology 2007;369(2):229-33.
2007: Britta Dieckhoff; Jenny Puhlmann; Kristina Büscher; Angela Hafner-Marx; Nadja Herbach; Norbert Bannert; Mathias Büttner; Rüdiger Wanke; Reinhard Kurth; Joachim Denner
Expression of porcine endogenous retroviruses (PERVs) in melanomas of Munich miniature swine (MMS) Troll.
Veterinary microbiology 2007;123(1-3):53-68.
2007: B Dieckhoff; Alexander Karlas; A Hofmann; Wilfried Kues; B Petersen; A Pfeifer; H Niemann; Reinhard Kurth; Joachim Denner
Inhibition of porcine endogenous retroviruses (PERVs) in primary porcine cells by RNA interference using lentiviral vectors.
Archives of virology 2007;152(3):629-34.
2006: Joachim Denner; Ralf R Tönjes
Response to editors' letter in Xenotransplantation on manuscripts on porcine endogenous retroviruses.
Xenotransplantation 2006;13(4):282-3.
2006: Kristina Büscher; Silvia Hahn; Maja Hofmann; Uwe Trefzer; Muhsin Ozel; Wolfram Sterry; Johannes Löwer; Roswitha Löwer; Reinhard Kurth; Joachim Denner
Expression of the human endogenous retrovirus-K transmembrane envelope, Rec and Np9 proteins in melanomas and melanoma cell lines.
Melanoma research 2006;16(3):223-34.
2006: Uwe Fiebig; Manuel Garcia Hartmann; Norbert Bannert; Reinhard Kurth; Joachim Denner
Transspecies transmission of the endogenous koala retrovirus.
Journal of virology 2006;80(11):5651-4.
2006: Stefan Langhammer; Janine Hübner; Reinhard Kurth; Joachim Denner
Antibodies neutralizing feline leukaemia virus (FeLV) in cats immunized with the transmembrane envelope protein p15E.
Immunology 2006;117(2):229-37.
2005: Michal Amit; Monica E Winkler; Sandra Menke; Eva Brüning; Kristina Büscher; Joachim Denner; Axel Haverich; Joseph Itskovitz-Eldor; Ulrich Martin
No evidence for infection of human embryonic stem cells by feeder cell-derived murine leukemia viruses.
Stem cells (Dayton, Ohio) 2005;23(6):761-71.
2005: Kristina Büscher; Uwe Trefzer; Maja Hofmann; Wolfram Sterry; Reinhard Kurth; Joachim Denner
Expression of human endogenous retrovirus K in melanomas and melanoma cell lines.
Cancer research 2005;65(10):4172-80.
2005: S Langhammer; Uwe Fiebig; Reinhard Kurth; Joachim Denner
Neutralising antibodies against the transmembrane protein of feline leukaemia virus (FeLV).
Vaccine 2005;23(25):3341-8.
2005: Monica E Winkler; Michael Winkler; Rosemarie Burian; Jens M Hecker; Martin Loss; Michael Przemeck; Ralf Lorenz; Clive Patience; Alexander Karlas; Sebastian Sommer; Joachim Denner; Ulrich Martin
Analysis of pig-to-human porcine endogenous retrovirus transmission in a triple-species kidney xenotransplantation model.
Transplant international : official journal of the European Society for Organ Transplantation 2005;17(12):848-58.
2005: Markus Irgang; Alexander Karlas; Christine Laue; Volker Specke; Stefan J Tacke; Reinhard Kurth; Jurgen Schrezenmeir; Joachim Denner
Porcine endogenous retroviruses PERV-A and PERV-B infect neither mouse cells in vitro nor SCID mice in vivo.
Intervirology 2005;48(2-3):167-73.
2004: Olga Garkavenko; Margaret C Croxson; Markus Irgang; Alexander Karlas; Joachim Denner; Robert B Elliott
Monitoring for presence of potentially xenotic viruses in recipients of pig islet xenotransplantation.
Journal of clinical microbiology 2004;42(11):5353-6.
2004: Joachim Denner
[Report on the 7th Xenotransplantation Mini-Symposium at the Robert Koch Institute, Berlin, June 2004].
Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz 2004;47(10):1014-7.
2004: Alexander Karlas; Reinhard Kurth; Joachim Denner
Inhibition of porcine endogenous retroviruses by RNA interference: increasing the safety of xenotransplantation.
Virology 2004;325(1):18-23.
2003: Markus Irgang; Igor M Sauer; Alexander Karlas; Katrin Zeilinger; Jörg C Gerlach; Reinhard Kurth; Peter Neuhaus; Joachim Denner
Porcine endogenous retroviruses: no infection in patients treated with a bioreactor based on porcine liver cells.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2003;28(2):141-54.
2003: Joachim Denner; Volker Specke; Ulla Thiesen; Alexander Karlas; Reinhard Kurth
Genetic alterations of the long terminal repeat of an ecotropic porcine endogenous retrovirus during passage in human cells.
Virology 2003;314(1):125-33.
2003: Igor M Sauer; Dimitrios Kardassis; K Zeillinger; Andreas Pascher; A Gruenwald; Gesine Pless; Markus Irgang; M Kraemer; Gero Puhl; J Frank; A R Müller; T Steinmüller; Joachim Denner; Peter Neuhaus; Jörg C Gerlach
Clinical extracorporeal hybrid liver support--phase I study with primary porcine liver cells.
Xenotransplantation 2003;10(5):460-9.
2003: Volker Specke; Joachim Denner
[Porcine endogenous retroviruses (PERVs) and xenotransplantation. A risk for the recipient and for society?].
Deutsche medizinische Wochenschrift (1946) 2003;128(23):1301-6.
2003: Uwe Fiebig; Oliver Stephan; Reinhard Kurth; Joachim Denner
Neutralizing antibodies against conserved domains of p15E of porcine endogenous retroviruses: basis for a vaccine for xenotransplantation?
Virology 2003;307(2):406-13.
2003: Joachim Denner
Porcine endogenous retroviruses (PERVs) and xenotransplantation: screening for transmission in several clinical trials and in experimental models using non-human primates.
Annals of transplantation : quarterly of the Polish Transplantation Society 2003;8(3):39-48.
2003: Andre Simon; Christian Templin; Carsten Schröder; G Laaff; Rene Tessmann; Monica E Winkler; Stefan J Tacke; Joachim Denner; Boris A Lapin; MG Chikobava; Clive Patience; Gustav Steinhoff; V Z Agrba; Axel Haverich; Ulrich Martin
No evidence for productive PERV infection of baboon cells in in vivo infection model.
Annals of transplantation : quarterly of the Polish Transplantation Society 2003;8(3):24-34.
2003: Stefan J Tacke; Volker Specke; Joachim Denner
Differences in release and determination of subtype of porcine endogenous retroviruses produced by stimulated normal pig blood cells.
Intervirology 2003;46(1):17-24.
2002: Ulrich Martin; Stefan J Tacke; Andre Simon; Carsten Schröder; Karsten Wiebe; Boris A Lapin; Axel Haverich; Joachim Denner; Gustav Steinhoff
Absence of PERV specific humoral immune response in baboons after transplantation of porcine cells or organs.
Transplant international : official journal of the European Society for Organ Transplantation 2002;15(7):361-8.
2002: Volker Specke; H J Schuurman; Roland Plesker; Cheick Coulibaly; Muhsin Ozel; G Langford; Reinhard Kurth; Joachim Denner
Virus safety in xenotransplantation: first exploratory in vivo studies in small laboratory animals and non-human primates.
Transplant immunology 2002;9(2-4):281-8.
2002: Volker Specke; Roland Plesker; Cheick Coulibaly; Klaus Boller; Joachim Denner
Productive infection of a mink cell line with porcine endogenous retroviruses (PERVs) but lack of transmission to minks in vivo.
Archives of virology 2002;147(2):305-19.
2001: Oliver Stephan; J Schwendemann; Volker Specke; Stefan J Tacke; Klaus Boller; Joachim Denner
Porcine endogenous retroviruses (PERVs): generation of specific antibodies, development of an immunoperoxidase assay (IPA) and inhibition by AZT.
Xenotransplantation 2001;8(4):310-6.
2001: Volker Specke; S Rubant; Joachim Denner
Productive infection of human primary cells and cell lines with porcine endogenous retroviruses.
Virology 2001;285(2):177-80.
2001: Stefan J Tacke; K Bodusch; A Berg; Joachim Denner
Sensitive and specific immunological detection methods for porcine endogenous retroviruses applicable to experimental and clinical xenotransplantation.
Xenotransplantation 2001;8(2):125-35.
2001: Volker Specke; Stefan J Tacke; Klaus Boller; J Schwendemann; Joachim Denner
Porcine endogenous retroviruses: in vitro host range and attempts to establish small animal models.
The Journal of general virology 2001;82(Pt 4):837-44.
2001: Joachim Denner; Volker Specke; J Schwendemann; Stefan J Tacke
Porcine endogenous retroviruses (PERVs): adaptation to human cells and attempts to infect small animals and non-human primates.
Annals of transplantation : quarterly of the Polish Transplantation Society 2001;6(3):25-33.
2000: Stefan J Tacke; Volker Specke; Oliver Stephan; E Seibold; K Bodusch; Joachim Denner
Porcine endogenous retroviruses: diagnostic assays and evidence for immunosuppressive properties.
Transplantation proceedings 2000;32(5):1166.
2000: Joachim Denner
How does HIV induce AIDS? The virus protein hypothesis.
Journal of human virology 2000;3(2):81-2.
2000: Stefan J Tacke; Reinhard Kurth; Joachim Denner
Porcine endogenous retroviruses inhibit human immune cell function: risk for xenotransplantation?
Virology 2000;268(1):87-93.
1998: Joachim Denner
Immunosuppression by retroviruses: implications for xenotransplantation.
Annals of the New York Academy of Sciences 1998;862():75-86.
1998: Roswitha Löwer; Ralf R Tönjes; Klaus Boller; Joachim Denner; B Kaiser; R C Phelps; Johannes Löwer; Reinhard Kurth; Klaus Badenhoop; H Donner; K H Usadel; Thomas Miethke; MS Lapatschek; Hermann Wagner
Development of insulin-dependent diabetes mellitus does not depend on specific expression of the human endogenous retrovirus HERV-K.
Cell 1998;95(1):11-4; discussion 16.
1998: Brigitte E Beer; Joachim Denner; Charles R Brown; Stephen Norley; Jan zur Megede; Cheick Coulibaly; Roland Plesker; Silke Holzammer; M Baier; Vanessa M Hirsch; Reinhard Kurth
Simian immunodeficiency virus of African green monkeys is apathogenic in the newborn natural host.
Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association 1998;18(3):210-20.
1996: Joachim Denner; C Persin; T Vogel; Dieter Haustein; Stephen Norley; Reinhard Kurth
The immunosuppressive peptide of HIV-1 inhibits T and B lymphocyte stimulation.
Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association 1996;12(5):442-50.
1996: Ralf R Tönjes; Roswitha Löwer; Klaus Boller; Joachim Denner; B Hasenmaier; H Kirsch; herbert koenig; Christoph Korbmacher; C Limbach; R Lugert; R C Phelps; J Scherer; K Thelen; Johannes Löwer; Reinhard Kurth
HERV-K: the biologically most active human endogenous retrovirus family.
Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association 1996;13 Suppl 1():S261-7.
1995: W Vogetseder; Joachim Denner; Klaus Boller; Reinhard Kurth; Manfred P Dierich
Human endogenous retrovirus K does not encode mouse mammary tumor virus-related antigens in human breast carcinomas.
AIDS research and human retroviruses 1995;11(7):869-72.
1994: Joachim Denner; Stephen Norley; Reinhard Kurth
The immunosuppressive peptide of HIV-1: functional domains and immune response in AIDS patients.
AIDS (London, England) 1994;8(8):1063-72.
1991: Reinhard Kurth; D Binninger; J Ennen; Joachim Denner; S Hartung; Stephen Norley
The quest for an AIDS vaccine: the state of the art and current challenges.
AIDS research and human retroviruses 1991;7(5):425-33.
1991: Reinhard Kurth; D Binninger; J Ennen; Joachim Denner; S Hartung; Stephen Norley
[Prospects for vaccine development against HIV infection].
Verhandlungen der Deutschen Gesellschaft für Innere Medizin 1991;97():394-402.