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Edward Dennis

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Chemicals & Drugs

Anatomy

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Mice

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Enzyme Activation

Disorders

Leukemia P388

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Co-Publications
Name
30
Balsinde, Jesús
20
Balboa, María
11
Deems, Raymond
11
Kokotos, George
9
Six, David
9
Witztum, Joseph
8
Friedman, Peter
8
Constantinou-Kokotou, Violetta
7
Stephens, Daren
6
Buczynski, Matthew
6
Harkewicz, Richard
5
Hörkkö, Sohvi
5
Lucas, Karin Killermann
5
Quehenberger, Oswald
5
Fahy, Eoin

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Publications

TOP 3
Grkovich Andrej; Armando Aaron; Quehenberger Oswald; Dennis Edward A
TLR-4 mediated group IVA phospholipase A(2) activation is phosphatidic acid phosphohydrolase 1 and protein kinase C dependent.
Barbayianni Efrosini; Stephens Daren; Grkovich Andrej; Magrioti Victoria; Hsu Yuan-Hao; Dolatzas Panagiotis; Kalogiannidis Dimitrios; Dennis Edward A; Kokotos George
2-Oxoamide inhibitors of phospholipase A2 activity and cellular arachidonate release based on dipeptides and pseudodipeptides.
Gupta Shakti; Maurya Mano Ram; Stephens Daren L; Dennis Edward A; Subramaniam Shankar
An integrated model of eicosanoid metabolism and signaling based on lipidomics flux analysis.

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All Publications

2009: Grkovich Andrej; Armando Aaron; Quehenberger Oswald; Dennis Edward A
TLR-4 mediated group IVA phospholipase A(2) activation is phosphatidic acid phosphohydrolase 1 and protein kinase C dependent.
Biochimica et biophysica acta 2009;1791(10):975-82.
2009: Barbayianni Efrosini; Stephens Daren; Grkovich Andrej; Magrioti Victoria; Hsu Yuan-Hao; Dolatzas Panagiotis; Kalogiannidis Dimitrios; Dennis Edward A; Kokotos George
2-Oxoamide inhibitors of phospholipase A2 activity and cellular arachidonate release based on dipeptides and pseudodipeptides.
Bioorganic & medicinal chemistry 2009;17(13):4833-43.
2009: Gupta Shakti; Maurya Mano Ram; Stephens Daren L; Dennis Edward A; Subramaniam Shankar
An integrated model of eicosanoid metabolism and signaling based on lipidomics flux analysis.
Biophysical journal 2009;96(11):4542-51.
2009: Burke John E; Babakhani Arneh; Gorfe Alemayehu A; Kokotos George; Li Sheng; Woods Virgil L; McCammon J Andrew; Dennis Edward A
Location of inhibitors bound to group IVA phospholipase A2 determined by molecular dynamics and deuterium exchange mass spectrometry.
Journal of the American Chemical Society 2009;131(23):8083-91.
2009: Buczynski Matthew W; Dumlao Darren S; Dennis Edward A
Thematic Review Series: Proteomics. An integrated omics analysis of eicosanoid biology.
Journal of lipid research 2009;50(6):1015-38.
2009: Kalyvas Athena; Baskakis Constantinos; Magrioti Victoria; Constantinou-Kokotou Violetta; Stephens Daren; López-Vales Rubèn; Lu Jian-Qiang; Yong V Wee; Dennis Edward A; Kokotos George; David Samuel
Differing roles for members of the phospholipase A2 superfamily in experimental autoimmune encephalomyelitis.
Brain : a journal of neurology 2009;132(Pt 5):1221-35.
2009: Dennis Edward A
Founding, early history, and transformation of the Journal for Lipid Research to an American Society of Biochemistry and Molecular Biology journal.
Journal of lipid research 2009;50 Suppl():S3-8.
2009: Fahy Eoin; Subramaniam Shankar; Murphy Robert C; Nishijima Masahiro; Raetz Christian R H; Shimizu Takao; Spener Friedrich; van Meer Gerrit; Wakelam Michael J O; Dennis Edward A
Update of the LIPID MAPS comprehensive classification system for lipids.
Journal of lipid research 2009;50 Suppl():S9-14.
2009: Burke John E; Dennis Edward A
Phospholipase A2 structure/function, mechanism, and signaling.
Journal of lipid research 2009;50 Suppl():S237-42.
2009: Dennis Edward A
Lipidomics joins the omics evolution.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(7):2089-90.
2009: Burke John E; Dennis Edward A
Phospholipase A2 biochemistry.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 2009;23(1):49-59.
2009: Prévost Nicolas; Mitsios John V; Kato Hisashi; Burke John E; Dennis Edward A; Shimizu Takao; Shattil Sanford J
Group IVA cytosolic phospholipase A2 (cPLA2alpha) and integrin alphaIIbbeta3 reinforce each other's functions during alphaIIbbeta3 signaling in platelets.
Blood 2009;113(2):447-57.
2009: Grkovich Andrej; Dennis Edward A
Phosphatidic acid phosphohydrolase in the regulation of inflammatory signaling.
Advances in enzyme regulation 2009;49(1):114-20.
2008: Antonopoulou Georgia; Barbayianni Efrosini; Magrioti Victoria; Cotton Naomi; Stephens Daren; Constantinou-Kokotou Violetta; Dennis Edward A; Kokotos George
Structure-activity relationships of natural and non-natural amino acid-based amide and 2-oxoamide inhibitors of human phospholipase A(2) enzymes.
Bioorganic & medicinal chemistry 2008;16(24):10257-69.
2008: Burke John E; Hsu Yuan-Hao; Deems Raymond A; Li Sheng; Woods Virgil L; Dennis Edward A
A phospholipid substrate molecule residing in the membrane surface mediates opening of the lid region in group IVA cytosolic phospholipase A2.
The Journal of biological chemistry 2008;283(45):31227-36.
2008: Antonopoulou Georgia; Magrioti Victoria; Stephens Daren; Constantinou-Kokotou Violetta; Dennis Edward A; Kokotos George
Synthesis of 2-oxoamides based on sulfonamide analogs of gamma-amino acids and their activity on phospholipase A2.
Journal of peptide science : an official publication of the European Peptide Society 2008;14(10):1111-20.
2008: Quehenberger Oswald; Armando Aaron; Dumlao Darren; Stephens Daren L; Dennis Edward A
Lipidomics analysis of essential fatty acids in macrophages.
Prostaglandins, leukotrienes, and essential fatty acids 2008;79(3-5):123-9.
2008: Jacobsen Faith E; Buczynski Matthew W; Dennis Edward A; Cohen Seth M
A macrophage cell model for selective metalloproteinase inhibitor design.
Chembiochem : a European journal of chemical biology 2008;9(13):2087-95.
2008: Burke John E; Karbarz Mark J; Deems Raymond A; Li Sheng; Woods Virgil L; Dennis Edward A
Interaction of group IA phospholipase A2 with metal ions and phospholipid vesicles probed with deuterium exchange mass spectrometry.
Biochemistry 2008;47(24):6451-9.
2008: Harkewicz Richard; Hartvigsen Karsten; Almazan Felicidad; Dennis Edward A; Witztum Joseph L; Miller Yury I
Cholesteryl ester hydroperoxides are biologically active components of minimally oxidized low density lipoprotein.
The Journal of biological chemistry 2008;283(16):10241-51.
2008: Hsu Yuan-Hao; Burke John E; Stephens Daren L; Deems Raymond A; Li Sheng; Asmus Kyle M; Woods Virgil L; Dennis Edward A
Calcium binding rigidifies the C2 domain and the intradomain interaction of GIVA phospholipase A2 as revealed by hydrogen/deuterium exchange mass spectrometry.
The Journal of biological chemistry 2008;283(15):9820-7.
2007: Moutevelis-Minakakis Panagiota; Neokosmidi Afroditi; Filippakou Maria; Stephens Daren; Dennis Edward A; Kokotos George
Synthesis of lipophilic 2-oxoamides based on gamma-aminobutyric and delta-aminovaleric analogues and their activity against phospholipase A2.
Journal of peptide science : an official publication of the European Peptide Society 2007;13(10):634-41.
2007: Six David A; Barbayianni Efrosini; Loukas Vassilios; Constantinou-Kokotou Violetta; Hadjipavlou-Litina Dimitra; Stephens Daren; Wong Alan C; Magrioti Victoria; Moutevelis-Minakakis Panagiota; Baker Sharon F; Dennis Edward A; Kokotos George
Structure-activity relationship of 2-oxoamide inhibition of group IVA cytosolic phospholipase A2 and group V secreted phospholipase A2.
Journal of medicinal chemistry 2007;50(17):4222-35.
2007: Buczynski Matthew W; Stephens Daren L; Bowers-Gentry Rebecca C; Grkovich Andrej; Deems Raymond A; Dennis Edward A
TLR-4 and sustained calcium agonists synergistically produce eicosanoids independent of protein synthesis in RAW264.7 cells.
The Journal of biological chemistry 2007;282(31):22834-47.
2007: Harkewicz Richard; Fahy Eoin; Andreyev Alexander; Dennis Edward A
Arachidonate-derived dihomoprostaglandin production observed in endotoxin-stimulated macrophage-like cells.
The Journal of biological chemistry 2007;282(5):2899-910.
2007: Sud Manish; Fahy Eoin; Cotter Dawn; Brown Alex; Dennis Edward A; Glass Christopher K; Merrill Alfred H; Murphy Robert C; Raetz Christian R H; Russell David W; Subramaniam Shankar
LMSD: LIPID MAPS structure database.
Nucleic acids research 2007;35(Database issue):D527-32.
2007: Schmelzer Kara; Fahy Eoin; Subramaniam Shankar; Dennis Edward A
The lipid maps initiative in lipidomics.
Methods in enzymology 2007;432():171-83.
2007: Deems Raymond; Buczynski Matthew W; Bowers-Gentry Rebecca; Harkewicz Richard; Dennis Edward A
Detection and quantitation of eicosanoids via high performance liquid chromatography-electrospray ionization-mass spectrometry.
Methods in enzymology 2007;432():59-82.
2006: Schaloske Ralph H; Dennis Edward A
The phospholipase A2 superfamily and its group numbering system.
Biochimica et biophysica acta 2006;1761(11):1246-59.
2006: Grkovich Andrej; Johnson Christina A; Buczynski Matthew W; Dennis Edward A
Lipopolysaccharide-induced cyclooxygenase-2 expression in human U937 macrophages is phosphatidic acid phosphohydrolase-1-dependent.
The Journal of biological chemistry 2006;281(44):32978-87.
2006: Stephens Daren; Barbayianni Efrosini; Constantinou-Kokotou Violetta; Peristeraki Anna; Six David A; Cooper Jennifer; Harkewicz Richard; Deems Raymond A; Dennis Edward A; Kokotos George
Differential inhibition of group IVA and group VIA phospholipases A2 by 2-oxoamides.
Journal of medicinal chemistry 2006;49(9):2821-8.
2006: Raetz Christian R H; Garrett Teresa A; Reynolds C Michael; Shaw Walter A; Moore Jeff D; Smith Dale C; Ribeiro Anthony A; Murphy Robert C; Ulevitch Richard J; Fearns Colleen; Reichart Donna; Glass Christopher K; Benner Chris; Subramaniam Shankar; Harkewicz Richard; Bowers-Gentry Rebecca C; Buczynski Matthew W; Cooper Jennifer A; Deems Raymond A; Dennis Edward A
Kdo2-Lipid A of Escherichia coli, a defined endotoxin that activates macrophages via TLR-4.
Journal of lipid research 2006;47(5):1097-111.
2006: Yaksh Tony L; Kokotos George; Svensson Camilla I; Stephens Daren; Kokotos Christoforos G; Fitzsimmons Bethany; Hadjipavlou-Litina Dimitra; Hua Xiao-Ying; Dennis Edward A
Systemic and intrathecal effects of a novel series of phospholipase A2 inhibitors on hyperalgesia and spinal prostaglandin E2 release.
The Journal of pharmacology and experimental therapeutics 2006;316(1):466-75.
2005: Winstead Michelle V; Lucas Karin Killermann; Dennis Edward A
Group IV cytosolic phospholipase A2 mediates arachidonic acid release in H9c2 rat cardiomyocyte cells in response to hydrogen peroxide.
Prostaglandins & other lipid mediators 2005;78(1-4):55-66.
2005: Kessen Ursula A; Schaloske Ralph H; Stephens Daren L; Killermann Lucas Karin; Dennis Edward A
PGE2 release is independent of upregulation of Group V phospholipase A2 during long-term stimulation of P388D1 cells with LPS.
Journal of lipid research 2005;46(11):2488-96.
2005: Lucas Karin Killermann; Dennis Edward A
Distinguishing phospholipase A2 types in biological samples by employing group-specific assays in the presence of inhibitors.
Prostaglandins & other lipid mediators 2005;77(1-4):235-48.
2005: Shirai Yasuhito; Balsinde Jesús; Dennis Edward A
Localization and functional interrelationships among cytosolic Group IV, secreted Group V, and Ca2+-independent Group VI phospholipase A2s in P388D1 macrophages using GFP/RFP constructs.
Biochimica et biophysica acta 2005;1735(2):119-29.
2005: Constantinou-Kokotou Violetta; Peristeraki Anna; Kokotos Christoforos G; Six David A; Dennis Edward A
Synthesis and activity of 2-oxoamides containing long chain beta-amino acids.
Journal of peptide science : an official publication of the European Peptide Society 2005;11(7):431-5.
2005: Fahy Eoin; Subramaniam Shankar; Brown H Alex; Glass Christopher K; Merrill Alfred H; Murphy Robert C; Raetz Christian R H; Russell David W; Seyama Yousuke; Shaw Walter; Shimizu Takao; Spener Friedrich; van Meer Gerrit; VanNieuwenhze Michael S; White Stephen H; Witztum Joseph L; Dennis Edward A
A comprehensive classification system for lipids.
Journal of lipid research 2005;46(5):839-61.
2005: Boullier Agnès; Friedman Peter; Harkewicz Richard; Hartvigsen Karsten; Green Simone R; Almazan Felicidad; Dennis Edward A; Steinberg Daniel; Witztum Joseph L; Quehenberger Oswald
Phosphocholine as a pattern recognition ligand for CD36.
Journal of lipid research 2005;46(5):969-76.
2005: Lucas Karin Killermann; Svensson Camilla I; Hua Xiao-Ying; Yaksh Tony L; Dennis Edward A
Spinal phospholipase A2 in inflammatory hyperalgesia: role of group IVA cPLA2.
British journal of pharmacology 2005;144(7):940-52.
2005: Schaloske Ralph H; Provins Jarrod W; Kessen Ursula A; Dennis Edward A
Molecular characterization of the lipopolysaccharide/platelet activating factor- and zymosan-induced pathways leading to prostaglandin production in P388D1 macrophages.
Biochimica et biophysica acta 2005;1687(1-3):64-75.
2005: Svensson C I; Lucas K K; Hua X-Y; Powell H C; Dennis E A; Yaksh T L
Spinal phospholipase A2 in inflammatory hyperalgesia: role of the small, secretory phospholipase A2.
Neuroscience 2005;133(2):543-53.
2004: Kokotos George; Six David A; Loukas Vassilios; Smith Timothy; Constantinou-Kokotou Violetta; Hadjipavlou-Litina Dimitra; Kotsovolou Stavroula; Chiou Antonia; Beltzner Christopher C; Dennis Edward A
Inhibition of group IVA cytosolic phospholipase A2 by novel 2-oxoamides in vitro, in cells, and in vivo.
Journal of medicinal chemistry 2004;47(14):3615-28.
2004: Boegeman Scott C; Deems Raymond A; Dennis Edward A
Phospholipid binding and the activation of group IA secreted phospholipase A2.
Biochemistry 2004;43(13):3907-16.
2004: Lucas Karin Killermann; Dennis Edward A
The ABC's of Group IV cytosolic phospholipase A2.
Biochimica et biophysica acta 2004;1636(2-3):213-8.
2003: Balboa María A; Shirai Yasuhito; Gaietta Guido; Ellisman Mark H; Balsinde Jesús; Dennis Edward A
Localization of group V phospholipase A2 in caveolin-enriched granules in activated P388D1 macrophage-like cells.
The Journal of biological chemistry 2003;278(48):48059-65.
2003: Phillips Rebecca M; Six David A; Dennis Edward A; Ghosh Partho
In vivo phospholipase activity of the Pseudomonas aeruginosa cytotoxin ExoU and protection of mammalian cells with phospholipase A2 inhibitors.
The Journal of biological chemistry 2003;278(42):41326-32.
2003: Six David A; Dennis Edward A
Essential Ca(2+)-independent role of the group IVA cytosolic phospholipase A(2) C2 domain for interfacial activity.
The Journal of biological chemistry 2003;278(26):23842-50.
2002: Whiles Jennifer A; Deems Raymond; Vold Regitze R; Dennis Edward A
Bicelles in structure-function studies of membrane-associated proteins.
Bioorganic chemistry 2002;30(6):431-42.
2002: Balboa María A; Varela-Nieto Isabel; Killermann Lucas Karin; Dennis Edward A
Expression and function of phospholipase A(2) in brain.
FEBS letters 2002;531(1):12-7.
2002: Balsinde Jesús; Winstead Michelle V; Dennis Edward A
Phospholipase A(2) regulation of arachidonic acid mobilization.
FEBS letters 2002;531(1):2-6.
2002: Kokotos George; Kotsovolou Stavroula; Six David A; Constantinou-Kokotou Violetta; Beltzner Christopher C; Dennis Edward A
Novel 2-oxoamide inhibitors of human group IVA phospholipase A(2).
Journal of medicinal chemistry 2002;45(14):2891-3.
2002: Friedman Peter; Horkko Sohvi; Steinberg Daniel; Witztum Joseph L; Dennis Edward A
Correlation of antiphospholipid antibody recognition with the structure of synthetic oxidized phospholipids. Importance of Schiff base formation and aldol condensation.
The Journal of biological chemistry 2002;277(9):7010-20.
2001: Boullier A; Bird D A; Chang M K; Dennis E A; Friedman P; Gillotre-Taylor K; Hörkkö S; Palinski W; Quehenberger O; Shaw P; Steinberg D; Terpstra V; Witztum J L
Scavenger receptors, oxidized LDL, and atherosclerosis.
Annals of the New York Academy of Sciences 2001;947():214-22; discussion 222-3.
2001: Bernatchez P N; Winstead M V; Dennis E A; Sirois M G
VEGF stimulation of endothelial cell PAF synthesis is mediated by group V 14 kDa secretory phospholipase A2.
British journal of pharmacology 2001;134(1):197-205.
2001: Balboa M A; Balsinde J; Dennis E A
Inflammatory activation of prostaglandin production by microglial cells antagonized by amyloid peptide.
Biochemical and biophysical research communications 2001;280(2):558-60.
2000: Winstead M V; Balsinde J; Dennis E A
Calcium-independent phospholipase A(2): structure and function.
Biochimica et biophysica acta 2000;1488(1-2):28-39.
2000: Six D A; Dennis E A
The expanding superfamily of phospholipase A(2) enzymes: classification and characterization.
Biochimica et biophysica acta 2000;1488(1-2):1-19.
2000: Balsinde J; Balboa M A; Dennis E A
Identification of a third pathway for arachidonic acid mobilization and prostaglandin production in activated P388D1 macrophage-like cells.
The Journal of biological chemistry 2000;275(29):22544-9.
2000: Balsinde J; Balboa M A; Li W H; Llopis J; Dennis E A
Cellular regulation of cytosolic group IV phospholipase A2 by phosphatidylinositol bisphosphate levels.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(10):5398-402.
2000: Balsinde J; Balboa M A; Dennis E A
Group IV cytosolic phospholipase A2 activation by diacylglycerol pyrophosphate in murine P388D1 macrophages.
Annals of the New York Academy of Sciences 2000;905():11-5.
2000: Wang A; Johnson C A; Jones Y; Ellisman M H; Dennis E A
Subcellular localization and PKC-dependent regulation of the human lysophospholipase A/acyl-protein thioesterase in WISH cells.
Biochimica et biophysica acta 2000;1484(2-3):207-14.
2000: Boullier A; Gillotte K L; Hörkkö S; Green S R; Friedman P; Dennis E A; Witztum J L; Steinberg D; Quehenberger O
The binding of oxidized low density lipoprotein to mouse CD36 is mediated in part by oxidized phospholipids that are associated with both the lipid and protein moieties of the lipoprotein.
The Journal of biological chemistry 2000;275(13):9163-9.
2000: Dennis E A
Phospholipase A2 in eicosanoid generation.
American journal of respiratory and critical care medicine 2000;161(2 Pt 2):S32-5.
2000: Balsinde J; Balboa M A; Yedgar S; Dennis E A
Group V phospholipase A(2)-mediated oleic acid mobilization in lipopolysaccharide-stimulated P388D(1) macrophages.
The Journal of biological chemistry 2000;275(7):4783-6.
2000: Balboa M A; Balsinde J; Dennis E A
Phosphorylation of cytosolic group IV phospholipase A(2) is necessary but not sufficient for Arachidonic acid release in P388D(1) macrophages.
Biochemical and biophysical research communications 2000;267(1):145-8.
2000: Lefkowitz L J; Shinohara H; Dennis E A
Human group-V phospholipase-A2 expression in Pichia pastoris and its role in eicosanoid generation.
Ernst Schering Research Foundation workshop 2000;(31):25-52.
1999: Balboa M A; Balsinde J; Johnson C A; Dennis E A
Regulation of arachidonic acid mobilization in lipopolysaccharide-activated P388D(1) macrophages by adenosine triphosphate.
The Journal of biological chemistry 1999;274(51):36764-8.
1999: Lefkowitz L J; Deems R A; Dennis E A
Expression of group IA phospholipase A2 in Pichia pastoris: identification of a phosphatidylcholine activator site using site-directed mutagenesis.
Biochemistry 1999;38(43):14174-84.
1999: Johnson C A; Balboa M A; Balsinde J; Dennis E A
Regulation of cyclooxygenase-2 expression by phosphatidate phosphohydrolase in human amnionic WISH cells.
The Journal of biological chemistry 1999;274(39):27689-93.
1999: Balsinde J; Shinohara H; Lefkowitz L J; Johnson C A; Balboa M A; Dennis E A
Group V phospholipase A(2)-dependent induction of cyclooxygenase-2 in macrophages.
The Journal of biological chemistry 1999;274(37):25967-70.
1999: Yang H C; Mosior M; Ni B; Dennis E A
Regional distribution, ontogeny, purification, and characterization of the Ca2+-independent phospholipase A2 from rat brain.
Journal of neurochemistry 1999;73(3):1278-87.
1999: Ghomashchi F; Loo R; Balsinde J; Bartoli F; Apitz-Castro R; Clark J D; Dennis E A; Gelb M H
Trifluoromethyl ketones and methyl fluorophosphonates as inhibitors of group IV and VI phospholipases A(2): structure-function studies with vesicle, micelle, and membrane assays.
Biochimica et biophysica acta 1999;1420(1-2):45-56.
1999: Wang A; Dennis E A
Mammalian lysophospholipases.
Biochimica et biophysica acta 1999;1439(1):1-16.
1999: Chang M K; Bergmark C; Laurila A; Hörkkö S; Han K H; Friedman P; Dennis E A; Witztum J L
Monoclonal antibodies against oxidized low-density lipoprotein bind to apoptotic cells and inhibit their phagocytosis by elicited macrophages: evidence that oxidation-specific epitopes mediate macrophage recognition.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(11):6353-8.
1999: Bird D A; Gillotte K L; Hörkkö S; Friedman P; Dennis E A; Witztum J L; Steinberg D
Receptors for oxidized low-density lipoprotein on elicited mouse peritoneal macrophages can recognize both the modified lipid moieties and the modified protein moieties: implications with respect to macrophage recognition of apoptotic cells.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(11):6347-52.
1999: Yang H C; Mosior M; Johnson C A; Chen Y; Dennis E A
Group-specific assays that distinguish between the four major types of mammalian phospholipase A2.
Analytical biochemistry 1999;269(2):278-88.
1999: Shinohara H; Balboa M A; Johnson C A; Balsinde J; Dennis E A
Regulation of delayed prostaglandin production in activated P388D1 macrophages by group IV cytosolic and group V secretory phospholipase A2s.
The Journal of biological chemistry 1999;274(18):12263-8.
1999: Wang A; Yang H C; Friedman P; Johnson C A; Dennis E A
A specific human lysophospholipase: cDNA cloning, tissue distribution and kinetic characterization.
Biochimica et biophysica acta 1999;1437(2):157-69.
1999: Hörkkö S; Bird D A; Miller E; Itabe H; Leitinger N; Subbanagounder G; Berliner J A; Friedman P; Dennis E A; Curtiss L K; Palinski W; Witztum J L
Monoclonal autoantibodies specific for oxidized phospholipids or oxidized phospholipid-protein adducts inhibit macrophage uptake of oxidized low-density lipoproteins.
The Journal of clinical investigation 1999;103(1):117-28.
1999: Balboa M A; Balsinde J; Dillon D A; Carman G M; Dennis E A
Proinflammatory macrophage-activating properties of the novel phospholipid diacylglycerol pyrophosphate.
The Journal of biological chemistry 1999;274(1):522-6.
1999: Balsinde J; Balboa M A; Insel P A; Dennis E A
Regulation and inhibition of phospholipase A2.
Annual review of pharmacology and toxicology 1999;39():175-89.
1998: Chen Y; Dennis E A
Expression and characterization of human group V phospholipase A2.
Biochimica et biophysica acta 1998;1394(1):57-64.
1998: Balsinde J; Balboa M A; Dennis E A
Functional coupling between secretory phospholipase A2 and cyclooxygenase-2 and its regulation by cytosolic group IV phospholipase A2.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(14):7951-6.
1998: Lio Y C; Dennis E A
Interfacial activation, lysophospholipase and transacylase activity of group VI Ca2+-independent phospholipase A2.
Biochimica et biophysica acta 1998;1392(2-3):320-32.
1998: Segelke B W; Nguyen D; Chee R; Xuong N H; Dennis E A
Structures of two novel crystal forms of Naja naja naja phospholipase A2 lacking Ca2+ reveal trimeric packing.
Journal of molecular biology 1998;279(1):223-32.
1998: Balboa M A; Balsinde J; Dennis E A
Involvement of phosphatidate phosphohydrolase in arachidonic acid mobilization in human amnionic WISH cells.
The Journal of biological chemistry 1998;273(13):7684-90.
1998: Mosior M; Six D A; Dennis E A
Group IV cytosolic phospholipase A2 binds with high affinity and specificity to phosphatidylinositol 4,5-bisphosphate resulting in dramatic increases in activity.
The Journal of biological chemistry 1998;273(4):2184-91.
1997: Balsinde J; Balboa M A; Dennis E A
Antisense inhibition of group VI Ca2+-independent phospholipase A2 blocks phospholipid fatty acid remodeling in murine P388D1 macrophages.
The Journal of biological chemistry 1997;272(46):29317-21.
1997: Wang A; Loo R; Chen Z; Dennis E A
Regiospecificity and catalytic triad of lysophospholipase I.
The Journal of biological chemistry 1997;272(35):22030-6.
1997: Balsinde J; Balboa M A; Dennis E A
Inflammatory activation of arachidonic acid signaling in murine P388D1 macrophages via sphingomyelin synthesis.
The Journal of biological chemistry 1997;272(33):20373-7.
1997: Loo R W; Conde-Frieboes K; Reynolds L J; Dennis E A
Activation, inhibition, and regiospecificity of the lysophospholipase activity of the 85-kDa group IV cytosolic phospholipase A2.
The Journal of biological chemistry 1997;272(31):19214-9.
1997: Balsinde J; Dennis E A
Function and inhibition of intracellular calcium-independent phospholipase A2.
The Journal of biological chemistry 1997;272(26):16069-72.
1997: Wang A; Deems R A; Dennis E A
Cloning, expression, and catalytic mechanism of murine lysophospholipase I.
The Journal of biological chemistry 1997;272(19):12723-9.
1997: Balboa M A; Balsinde J; Jones S S; Dennis E A
Identity between the Ca2+-independent phospholipase A2 enzymes from P388D1 macrophages and Chinese hamster ovary cells.
The Journal of biological chemistry 1997;272(13):8576-80.
1997: Balsinde J; Balboa M A; Insel P A; Dennis E A
Differential regulation of phospholipase D and phospholipase A2 by protein kinase C in P388D1 macrophages.
The Biochemical journal 1997;321 ( Pt 3)():805-9.
1997: Dennis E A
The growing phospholipase A2 superfamily of signal transduction enzymes.
Trends in biochemical sciences 1997;22(1):1-2.
1996: Balboa M A; Balsinde J; Winstead M V; Tischfield J A; Dennis E A
Novel group V phospholipase A2 involved in arachidonic acid mobilization in murine P388D1 macrophages.
The Journal of biological chemistry 1996;271(50):32381-4.
1996: Balsinde J; Dennis E A
Bromoenol lactone inhibits magnesium-dependent phosphatidate phosphohydrolase and blocks triacylglycerol biosynthesis in mouse P388D1 macrophages.
The Journal of biological chemistry 1996;271(50):31937-41.
1996: Pickard R T; Chiou X G; Strifler B A; DeFelippis M R; Hyslop P A; Tebbe A L; Yee Y K; Reynolds L J; Dennis E A; Kramer R M; Sharp J D
Identification of essential residues for the catalytic function of 85-kDa cytosolic phospholipase A2. Probing the role of histidine, aspartic acid, cysteine, and arginine.
The Journal of biological chemistry 1996;271(32):19225-31.
1996: Lio Y C; Reynolds L J; Balsinde J; Dennis E A
Irreversible inhibition of Ca(2+)-independent phospholipase A2 by methyl arachidonyl fluorophosphonate.
Biochimica et biophysica acta 1996;1302(1):55-60.
1996: Balsinde J; Dennis E A
Distinct roles in signal transduction for each of the phospholipase A2 enzymes present in P388D1 macrophages.
The Journal of biological chemistry 1996;271(12):6758-65.
1996: Balsinde J; Dennis E A
The incorporation of arachidonic acid into triacylglycerol in P388D1 macrophage-like cells.
European journal of biochemistry / FEBS 1996;235(3):480-5.
1995: Ackermann E J; Dennis E A
Mammalian calcium-independent phospholipase A2.
Biochimica et biophysica acta 1995;1259(2):125-36.
1995: Balsinde J; Bianco I D; Ackermann E J; Conde-Frieboes K; Dennis E A
Inhibition of calcium-independent phospholipase A2 prevents arachidonic acid incorporation and phospholipid remodeling in P388D1 macrophages.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(18):8527-31.
1995: Bianco I D; Kelley M J; Crowl R M; Dennis E A
Identification of two specific lysines responsible for the inhibition of phospholipase A2 by manoalide.
Biochimica et biophysica acta 1995;1250(2):197-203.
1995: Reynolds L J; Kempner E S; Hughes L L; Dennis E A
Inactivation of secretory phospholipase A2 by ionizing radiation.
Biophysical journal 1995;68(5):2108-14.
1995: Plesniak L A; Yu L; Dennis E A
Conformation of micellar phospholipid bound to the active site of phospholipase A2.
Biochemistry 1995;34(15):4943-51.
1995: Ackermann E J; Conde-Frieboes K; Dennis E A
Inhibition of macrophage Ca(2+)-independent phospholipase A2 by bromoenol lactone and trifluoromethyl ketones.
The Journal of biological chemistry 1995;270(1):445-50.
1995: Dennis E A; Ackermann E J; Deems R A; Reynolds L J
Multiple forms of phospholipase A2 in macrophages capable of arachidonic acid release for eicosanoid biosynthesis.
Advances in prostaglandin, thromboxane, and leukotriene research 1995;23():75-80.
1994: Asmis R; Dennis E A
PAF stimulates cAMP formation in P388D1 macrophage-like cells via the formation and secretion of prostaglandin E2 in an autocrine fashion.
Biochimica et biophysica acta 1994;1224(2):295-301.
1994: Balsinde J; Barbour S E; Bianco I D; Dennis E A
Arachidonic acid mobilization in P388D1 macrophages is controlled by two distinct Ca(2+)-dependent phospholipase A2 enzymes.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(23):11060-4.
1994: Dennis E A
Diversity of group types, regulation, and function of phospholipase A2.
The Journal of biological chemistry 1994;269(18):13057-60.
1994: Asmis R; Randriamampita C; Tsien R Y; Dennis E A
Intracellular Ca2+, inositol 1,4,5-trisphosphate and additional signalling in the stimulation by platelet-activating factor of prostaglandin E2 formation in P388D1 macrophage-like cells.
The Biochemical journal 1994;298 Pt 3():543-51.
1994: Ackermann E J; Kempner E S; Dennis E A
Ca(2+)-independent cytosolic phospholipase A2 from macrophage-like P388D1 cells. Isolation and characterization.
The Journal of biological chemistry 1994;269(12):9227-33.
1994: Reynolds L J; Hughes L L; Yu L; Dennis E A
1-Hexadecyl-2-arachidonoylthio-2-deoxy-sn-glycero-3-phosphorylcholine as a substrate for the microtiterplate assay of human cytosolic phospholipase A2.
Analytical biochemistry 1994;217(1):25-32.
1994: Dennis E A; Krell R D
Summary: the enzymes, accessory proteins, and receptors of leukotriene metabolism and their inhibition and antagonism.
Advances in prostaglandin, thromboxane, and leukotriene research 1994;22():63-7.
1993: Barbour S E; Dennis E A
Antisense inhibition of group II phospholipase A2 expression blocks the production of prostaglandin E2 by P388D1 cells.
The Journal of biological chemistry 1993;268(29):21875-82.
1993: Yu L; Dennis E A
Effect of polar head groups on the interactions of phospholipase A2 with phosphonate transition-state analogues.
Biochemistry 1993;32(38):10185-92.
1993: Plesniak L A; Boegeman S C; Segelke B W; Dennis E A
Interaction of phospholipase A2 with thioether amide containing phospholipid analogues.
Biochemistry 1993;32(19):5009-16.
1993: Reynolds L J; Hughes L L; Louis A I; Kramer R M; Dennis E A
Metal ion and salt effects on the phospholipase A2, lysophospholipase, and transacylase activities of human cytosolic phospholipase A2.
Biochimica et biophysica acta 1993;1167(3):272-80.
1993: Stafford R E; Zhang Y Y; Deems R A; Dennis E A
Kinetic analysis and substrate specificity of a lysophospholipase from the macrophage-like cell line P388D1.
Biochimica et biophysica acta 1993;1167(1):43-8.
1993: Fremont D H; Anderson D H; Wilson I A; Dennis E A; Xuong N H
Crystal structure of phospholipase A2 from Indian cobra reveals a trimeric association.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(1):342-6.
1992: Davidson F F; Dennis E A
Limitations of phosphatidylcholine/deoxycholate mixtures for the analysis of phospholipase A2 inhibition and activation: illustration with annexins.
Biochimica et biophysica acta 1992;1127(3):270-6.
1992: Reynolds L J; Hughes L L; Dennis E A
Analysis of human synovial fluid phospholipase A2 on short chain phosphatidylcholine-mixed micelles: development of a spectrophotometric assay suitable for a microtiterplate reader.
Analytical biochemistry 1992;204(1):190-7.
1992: Kelley M J; Crowl R M; Dennis E A
Renaturation of cobra venom phospholipase A2 expressed from a synthetic gene in Escherichia coli.
Biochimica et biophysica acta 1992;1118(2):107-15.
1992: Dennis E A; Deems R A; Yu L
Extracellular phospholipase A2.
Advances in experimental medicine and biology 1992;318():35-9.
1991: Yu L; Dennis E A
Critical role of a hydrogen bond in the interaction of phospholipase A2 with transition-state and substrate analogues.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(20):9325-9.
1991: Reynolds L J; Mihelich E D; Dennis E A
Inhibition of venom phospholipases A2 by manoalide and manoalogue. Stoichiometry of incorporation.
The Journal of biological chemistry 1991;266(25):16512-7.
1991: Dennis E A; Rhee S G; Billah M M; Hannun Y A
Role of phospholipase in generating lipid second messengers in signal transduction.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1991;5(7):2068-77.
1991: Washburn W N; Dennis E A
Suicide-inhibitory bifunctionally linked substrates (SIBLINKS) as phospholipase A2 inhibitors. Mechanistic implications.
The Journal of biological chemistry 1991;266(8):5042-8.
1991: Reynolds L J; Washburn W N; Deems R A; Dennis E A
Assay strategies and methods for phospholipases.
Methods in enzymology 1991;197():3-23.
1991: Kempner E S; Osborne J C; Reynolds L J; Deems R A; Dennis E A
Analysis of lipases by radiation inactivation.
Methods in enzymology 1991;197():280-8.
1991: Glaser K B; Asmis R; Dennis E A
PAF receptor mediated PGE2 production in LPS primed P388D1 macrophage-like cells.
Advances in prostaglandin, thromboxane, and leukotriene research 1991;21A():249-55.
1990: Glaser K B; Asmis R; Dennis E A
Bacterial lipopolysaccharide priming of P388D1 macrophage-like cells for enhanced arachidonic acid metabolism. Platelet-activating factor receptor activation and regulation of phospholipase A2.
The Journal of biological chemistry 1990;265(15):8658-64.
1990: Davidson F F; Lister M D; Dennis E A
Binding and inhibition studies on lipocortins using phosphatidylcholine vesicles and phospholipase A2 from snake venom, pancreas, and a macrophage-like cell line.
The Journal of biological chemistry 1990;265(10):5602-9.
1990: Yu L; Deems R A; Hajdu J; Dennis E A
The interaction of phospholipase A2 with phospholipid analogues and inhibitors.
The Journal of biological chemistry 1990;265(5):2657-64.
1990: Davidson F F; Dennis E A
Amino acid sequence and circular dichroism of Indian cobra (Naja naja naja) venom acidic phospholipase A2.
Biochimica et biophysica acta 1990;1037(1):7-15.
1990: Glaser K B; Lister M D; Ulevitch R J; Dennis E A
Macrophage phospholipase A2 activity and eicosanoid production: studies with phospholipase A2 inhibitors in P388D1 cells.
Advances in experimental medicine and biology 1990;275():1-16.
1990: Dennis E A
Modification of the arachidonic acid cascade through phospholipase A2 dependent mechanisms.
Advances in prostaglandin, thromboxane, and leukotriene research 1990;20():217-23.
1990: Dennis E A; Davidson F F
Phospholipase A2 and lipocortin effects.
Progress in clinical and biological research 1990;349():47-54.
1990: Hazlett T L; Deems R A; Dennis E A
Activation, aggregation, inhibition and the mechanism of phospholipase A2.
Advances in experimental medicine and biology 1990;279():49-64.
1989: Davidson F F; Dennis E A
Biological relevance of lipocortins and related proteins as inhibitors of phospholipase A2.
Biochemical pharmacology 1989;38(21):3645-51.
1989: Fanni T; Deems R A; Dennis E A
18O isotope exchange experiments on phospholipase A2 determined by 13C-NMR: monomeric phosphatidylcholine and micellar phosphatidylethanolamine substrates.
Biochimica et biophysica acta 1989;1004(1):134-8.
1989: Stafford R E; Fanni T; Dennis E A
Interfacial properties and critical micelle concentration of lysophospholipids.
Biochemistry 1989;28(12):5113-20.
1989: Lister M D; Glaser K B; Ulevitch R J; Dennis E A
Inhibition studies on the membrane-associated phospholipase A2 in vitro and prostaglandin E2 production in vivo of the macrophage-like P388D1 cell. Effects of manoalide, 7,7-dimethyl-5,8-eicosadienoic acid, and p-bromophenacyl bromide.
The Journal of biological chemistry 1989;264(15):8520-8.
1988: Zhang Y Y; Dennis E A
Purification and characterization of a lysophospholipase from a macrophage-like cell line P388D1.
The Journal of biological chemistry 1988;263(20):9965-72.
1988: Hazlett T L; Dennis E A
Lipid-induced aggregation of phospholipase A2: sucrose density gradient ultracentrifugation and crosslinking studies.
Biochimica et biophysica acta 1988;961(1):22-9.
1988: Lister M D; Deems R A; Watanabe Y; Ulevitch R J; Dennis E A
Kinetic analysis of the Ca2+-dependent, membrane-bound, macrophage phospholipase A2 and the effects of arachidonic acid.
The Journal of biological chemistry 1988;263(16):7506-13.
1988: Ulevitch R J; Watanabe Y; Sano M; Lister M D; Deems R A; Dennis E A
Solubilization, purification, and characterization of a membrane-bound phospholipase A2 from the P388D1 macrophage-like cell line.
The Journal of biological chemistry 1988;263(7):3079-85.
1988: Hazlett T L; Dennis E A
Effect of phospholipids on fluorescence polarization and lifetimes of fluorescein-labeled phospholipase A2.
Biochimica et biophysica acta 1988;958(2):172-8.
1986: Dennis E A
Micellization and solubilization of phospholipids by surfactants.
Advances in colloid and interface science 1986;26(2-4):155-75.

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