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Christopher Denny

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Chemicals & Drugs

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Publications

TOP 3
Jennifer L Anderson; Christopher T Denny; William D Tap; Noah Federman
Pediatric sarcomas: translating molecular pathogenesis of disease to novel therapeutic possibilities.
Noah Federman; Hyunggyoo Kang; Elliot M Landaw; Bin Liu; James D Marks; Katelyn McCabe; Jon O Nagy; Timothy Triche; Anna M Wu; Jason Chan; Christopher T Denny
Enhanced growth inhibition of osteosarcoma by cytotoxic polymerized liposomal nanoparticles targeting the alcam cell surface receptor.
Alan K Ikeda; Dejah R Judelson; Noah Federman; Keith B Glaser; Elliot M Landaw; Christopher T Denny; Kathleen M Sakamoto
ABT-869 inhibits the proliferation of Ewing Sarcoma cells and suppresses platelet-derived growth factor receptor beta and c-KIT signaling pathways.

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All Publications

2012: Jennifer L Anderson; Christopher T Denny; William D Tap; Noah Federman
Pediatric sarcomas: translating molecular pathogenesis of disease to novel therapeutic possibilities.
Pediatric research 2012;72(2):112-21.
2012: Noah Federman; Hyunggyoo Kang; Elliot M Landaw; Bin Liu; James D Marks; Katelyn McCabe; Jon O Nagy; Timothy Triche; Anna M Wu; Jason Chan; Christopher T Denny
Enhanced growth inhibition of osteosarcoma by cytotoxic polymerized liposomal nanoparticles targeting the alcam cell surface receptor.
Sarcoma 2012;2012():126906.
2010: Alan K Ikeda; Dejah R Judelson; Noah Federman; Keith B Glaser; Elliot M Landaw; Christopher T Denny; Kathleen M Sakamoto
ABT-869 inhibits the proliferation of Ewing Sarcoma cells and suppresses platelet-derived growth factor receptor beta and c-KIT signaling pathways.
Molecular cancer therapeutics 2010;9(3):653-60.
2008: Gary Potikyan; Kelly A France; Marc R J Carlson; Jun Dong; Stanley F Nelson; Christopher T Denny
Genetically defined EWS/FLI1 model system suggests mesenchymal origin of Ewing's family tumors.
Laboratory investigation; a journal of technical methods and pathology 2008;88(12):1291-302.
2003: Benjamin Deneen; Habib Hamidi; Christopher T Denny
Functional analysis of the EWS/ETS target gene uridine phosphorylase.
Cancer research 2003;63(14):4268-74.
2003: Benjamin Deneen; Scott M Welford; Thu Ho; Felicia Hernandez; Irwin Kurland; Christopher T Denny
PIM3 proto-oncogene kinase is a common transcriptional target of divergent EWS/ETS oncoproteins.
Molecular and cellular biology 2003;23(11):3897-908.
2001: Scott M Welford; S P Hebert; Benjamin Deneen; A Arvand; Christopher T Denny
DNA binding domain-independent pathways are involved in EWS/FLI1-mediated oncogenesis.
The Journal of biological chemistry 2001;276(45):41977-84.
2001: Benjamin Deneen; Christopher T Denny
Loss of p16 pathways stabilizes EWS/FLI1 expression and complements EWS/FLI1 mediated transformation.
Oncogene 2001;20(46):6731-41.
2001: A Arvand; Christopher T Denny
Biology of EWS/ETS fusions in Ewing's family tumors.
Oncogene 2001;20(40):5747-54.
2001: Christopher T Denny
Defining small round cell tumors of childhood: when is a rose really a rose.
Journal of pediatric hematology/oncology 2001;23(6):338-9.
2001: A Arvand; Scott M Welford; Michael A Teitell; Christopher T Denny
The COOH-terminal domain of FLI-1 is necessary for full tumorigenesis and transcriptional modulation by EWS/FLI-1.
Cancer research 2001;61(13):5311-7.
2000: YH Im; Heung Tae Kim; Chan Lee; D Poulin; Scott M Welford; Poul H B Sorensen; Christopher T Denny; Seong-Jin Kim
EWS-FLI1, EWS-ERG, and EWS-ETV1 oncoproteins of Ewing tumor family all suppress transcription of transforming growth factor beta type II receptor gene.
Cancer research 2000;60(6):1536-40.
2000: A I Kim; S P Hebert; Christopher T Denny
Cross-contamination limits the use of recycled anion exchange resins for preparing plasmid DNA.
BioTechniques 2000;28(2):298.
1999: Michael A Teitell; AD Thompson; Poul H B Sorensen; H Shimada; Timothy Triche; Christopher T Denny
EWS/ETS fusion genes induce epithelial and neuroectodermal differentiation in NIH 3T3 fibroblasts.
Laboratory investigation; a journal of technical methods and pathology 1999;79(12):1535-43.
1999: AD Thompson; Michael A Teitell; A Arvand; Christopher T Denny
Divergent Ewing's sarcoma EWS/ETS fusions confer a common tumorigenic phenotype on NIH3T3 cells.
Oncogene 1999;18(40):5506-13.
1999: Michael A Teitell; Michael A Damore; Giri Sulur; D E Turner; M H Stern; Jonathan W Said; Christopher T Denny; Randolph Wall
TCL1 oncogene expression in AIDS-related lymphomas and lymphoid tissues.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(17):9809-14.
1998: A Arvand; Holger Bastians; Scott M Welford; AD Thompson; Joan V Ruderman; Christopher T Denny
EWS/FLI1 up regulates mE2-C, a cyclin-selective ubiquitin conjugating enzyme involved in cyclin B destruction.
Oncogene 1998;17(16):2039-45.
1998: Christopher T Denny
Ewing's sarcoma--a clinical enigma coming into focus.
Journal of pediatric hematology/oncology 1998;20(5):421-5.
1998: Scott M Welford; Jeffrey P Gregg; E Chen; D Garrison; Poul H B Sorensen; Christopher T Denny; Stanley F Nelson
Detection of differentially expressed genes in primary tumor tissues using representational differences analysis coupled to microarray hybridization.
Nucleic acids research 1998;26(12):3059-65.
1998: David D Chang; No-Hee Park; Christopher T Denny; Stanley F Nelson; M Pe
Characterization of transformation related genes in oral cancer cells.
Oncogene 1998;16(15):1921-30.
1997: William A. May; A Arvand; AD Thompson; Benjamin S Braun; M Wright; Christopher T Denny
EWS/FLI1-induced manic fringe renders NIH 3T3 cells tumorigenic.
Nature genetics 1997;17(4):495-7.
1997: William A. May; Christopher T Denny
Biology of EWS/FLI and related fusion genes in Ewing's sarcoma and primitive neuroectodermal tumor.
Current topics in microbiology and immunology 1997;220():143-50.
1996: AD Thompson; Benjamin S Braun; A Arvand; S D Stewart; William A. May; E Chen; J Korenberg; Christopher T Denny
EAT-2 is a novel SH2 domain containing protein that is up regulated by Ewing's sarcoma EWS/FLI1 fusion gene.
Oncogene 1996;13(12):2649-58.
1996: AA Thompson; S A Omori; M J Gilly; William A. May; M S Gordon; W J Wood; E Miyoshi; C S Malone; J Gimble; Christopher T Denny; Randolph Wall
Alternatively spliced exons encode the tissue-specific 5' termini of leukocyte pp52 and stromal cell S37 mRNA isoforms.
Genomics 1996;32(3):352-7.
1996: Christopher T Denny
Gene rearrangements in Ewing's sarcoma.
Cancer investigation 1996;14(1):83-8.
1995: Benjamin S Braun; R Frieden; Stephen L Lessnick; William A. May; Christopher T Denny
Identification of target genes for the Ewing's sarcoma EWS/FLI fusion protein by representational difference analysis.
Molecular and cellular biology 1995;15(8):4623-30.
1995: A D Brown; D Lopez-Terrada; Christopher T Denny; K A Lee
Promoters containing ATF-binding sites are de-regulated in cells that express the EWS/ATF1 oncogene.
Oncogene 1995;10(9):1749-56.
1995: I S Jeon; James Davis; Benjamin S Braun; JE Sublett; M F Roussel; Christopher T Denny; DN Shapiro
A variant Ewing's sarcoma translocation (7;22) fuses the EWS gene to the ETS gene ETV1.
Oncogene 1995;10(6):1229-34.
1995: Stephen L Lessnick; Benjamin S Braun; Christopher T Denny; William A. May
Multiple domains mediate transformation by the Ewing's sarcoma EWS/FLI-1 fusion gene.
Oncogene 1995;10(3):423-31.
1995: K Woodruff; N Wang; William A. May; E Adrone; Christopher T Denny; S A Feig
The clonal nature of mediastinal germ cell tumors and acute myelogenous leukemia. A case report and review of the literature.
Cancer genetics and cytogenetics 1995;79(1):25-31.
1994: Poul H B Sorensen; Stephen L Lessnick; D Lopez-Terrada; X F Liu; Timothy Triche; Christopher T Denny
A second Ewing's sarcoma translocation, t(21;22), fuses the EWS gene to another ETS-family transcription factor, ERG.
Nature genetics 1994;6(2):146-51.
1993: William A. May; Stephen L Lessnick; Benjamin S Braun; Michael J Klemsz; B C Lewis; L B Lunsford; Robert Hromas; Christopher T Denny
The Ewing's sarcoma EWS/FLI-1 fusion gene encodes a more potent transcriptional activator and is a more powerful transforming gene than FLI-1.
Molecular and cellular biology 1993;13(12):7393-8.
1993: William A. May; M L Gishizky; Stephen L Lessnick; L B Lunsford; B C Lewis; O Delattre; J Zucman; G Thomas; Christopher T Denny
Ewing sarcoma 11;22 translocation produces a chimeric transcription factor that requires the DNA-binding domain encoded by FLI1 for transformation.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(12):5752-6.
1993: W J Wood; AA Thompson; Julie R Korenberg; Xiao-Ning Chen; William A. May; Randolph Wall; Christopher T Denny
Isolation and chromosomal mapping of the human immunoglobulin-associated B29 gene (IGB).
Genomics 1993;16(1):187-92.
1993: William A. May; Julie R Korenberg; Xiao-Ning Chen; L Lunsford; W J Wood; A Thompson; Randolph Wall; Christopher T Denny
Human lymphocyte-specific pp52 gene is a member of a highly conserved dispersed family.
Genomics 1993;15(3):515-20.
1993: Robert Hromas; William A. May; Christopher T Denny; W Raskind; J Moore; Richard A Maki; E Beck; Michael J Klemsz
Human FLI-1 localizes to chromosome 11Q24 and has an aberrant transcript in neuroepithelioma.
Biochimica et biophysica acta 1993;1172(1-2):155-8.
1992: B C Lewis; N P Shah; Benjamin S Braun; Christopher T Denny
Creation of a yeast artificial chromosome fragmentation vector based on lysine-2.
Genetic analysis, techniques and applications 1992;9(3):86-90.
1991: N P Shah; Owen N Witte; Christopher T Denny
Characterization of the BCR promoter in Philadelphia chromosome-positive and -negative cell lines.
Molecular and cellular biology 1991;11(4):1854-60.
1990: J M Feingold; S D Ogden; Christopher T Denny
Streamlined approach to creating yeast artificial chromosome libraries from specialized cell sources.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(21):8637-41.
1989: Christopher T Denny; N P Shah; S Ogden; Cheryl L Willman; T McConnell; William M Crist; A Carroll; Owen N Witte
Localization of preferential sites of rearrangement within the BCR gene in Philadelphia chromosome-positive acute lymphoblastic leukemia.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(11):4254-8.