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Paul Denton

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TOP 3
Morgan L Chateau; Paul W Denton; Ian McGowan; Michael D Swanson; Jose Garcia-Martinez
Rectal transmission of transmitted/founder HIV-1 is efficiently prevented by topical 1% tenofovir in BLT humanized mice.
Paul W Denton; J P Di Santo; S K Choudhary; J F Krisko; A Lim; D M Margolis; F Martinez-Torres; T Nochi; R Olesen; A Wahl; W Zou; Jose Garcia-Martinez
IL-2 receptor γ-chain molecule is critical for intestinal T-cell reconstitution in humanized mice.
Paul W Denton; J Victor Garcia
Mucosal HIV-1 transmission and prevention strategies in BLT humanized mice.

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All Publications

2013: Morgan L Chateau; Paul W Denton; Ian McGowan; Michael D Swanson; Jose Garcia-Martinez
Rectal transmission of transmitted/founder HIV-1 is efficiently prevented by topical 1% tenofovir in BLT humanized mice.
PloS one 2013;8(3):e60024.
2012: Paul W Denton; J P Di Santo; S K Choudhary; J F Krisko; A Lim; D M Margolis; F Martinez-Torres; T Nochi; R Olesen; A Wahl; W Zou; Jose Garcia-Martinez
IL-2 receptor γ-chain molecule is critical for intestinal T-cell reconstitution in humanized mice.
Mucosal immunology 2012;5(5):555-66.
2012: Paul W Denton; J Victor Garcia
Mucosal HIV-1 transmission and prevention strategies in BLT humanized mice.
Trends in microbiology 2012;20(6):268-74.
2012: Angela Wahl; Morgan Chateau; Paul W Denton; Tomonori Nochi; Rikke Olesen; Michael D Swanson; J Victor Garcia
Human breast milk and antiretrovirals dramatically reduce oral HIV-1 transmission in BLT humanized mice.
PLoS pathogens 2012;8(6):e1002732.
2012: Wei Zou; Paul W Denton; John L Foster; John F Krisko; Tomonori Nochi; Richard L Watkins; Jose Garcia-Martinez
Nef functions in BLT mice to enhance HIV-1 replication and deplete CD4+CD8+ thymocytes.
Retrovirology 2012;9():44.
2011: Paul W Denton; Jacob D Estes; Elisa Fleming; Philippe Gallay; Ettore Appella; Michael S Kay; John F Krisko; Youn Tae Kwak; Min Lu; Francisco Martinez-Torres; Florence Othieno; Deborah A Payne; Daniel A Powell; Angela Wahl; Brett D Welch; Sima Zein; Wei Zou; Jose Garcia-Martinez
One percent tenofovir applied topically to humanized BLT mice and used according to the CAPRISA 004 experimental design demonstrates partial protection from vaginal HIV infection, validating the BLT model for evaluation of new microbicide candidates.
Journal of virology 2011;85(15):7582-93.
2011: Paul W Denton; J Víctor García
Humanized mouse models of HIV infection.
AIDS reviews 2011;13(3):135-48.
2010: Paul W Denton; John F Krisko; Daniel A Powell; Melissa Mathias; Youn-Tae Kwak; Francisco Martinez-Torres; Wei Zou; Deborah A Payne; Jacob D Estes; Jose Garcia-Martinez
Systemic administration of antiretrovirals prior to exposure prevents rectal and intravenous HIV-1 transmission in humanized BLT mice.
PloS one 2010;5(1):e8829.
2009: Paul W Denton; Jose Garcia-Martinez
Novel humanized murine models for HIV research.
Current HIV/AIDS reports 2009;6(1):13-9.
2008: Paul W Denton; Jacob D Estes; Zhifeng Sun; Florence A Othieno; Bangdong L Wei; Anja K Wege; Daniel A Powell; Deborah Payne; Ashley T Haase; Jose Garcia-Martinez
Antiretroviral pre-exposure prophylaxis prevents vaginal transmission of HIV-1 in humanized BLT mice.
PLoS medicine 2008;5(1):e16.
2008: A K Wege; Michael W Melkus; Paul W Denton; J D Estes; Jose Garcia-Martinez
Functional and phenotypic characterization of the humanized BLT mouse model.
Current topics in microbiology and immunology 2008;324():149-65.
2007: Zhifeng Sun; Paul W Denton; Jacob D Estes; Florence A Othieno; Bangdong L Wei; Anja K Wege; Michael W Melkus; Angela Padgett-Thomas; Mary Zupancic; Ashley T Haase; Jose Garcia-Martinez
Intrarectal transmission, systemic infection, and CD4+ T cell depletion in humanized mice infected with HIV-1.
The Journal of experimental medicine 2007;204(4):705-14.
2006: Michael W Melkus; Jacob D Estes; Angela Padgett-Thomas; Joel Gatlin; Paul W Denton; Florence A Othieno; Anja K Wege; Ashley T Haase; Jose Garcia-Martinez
Humanized mice mount specific adaptive and innate immune responses to EBV and TSST-1.
Nature medicine 2006;12(11):1316-22.
2005: Bangdong L Wei; Paul W Denton; Eduardo O'Neill; Tianci Luo; John L Foster; Jose Garcia-Martinez
Inhibition of lysosome and proteasome function enhances human immunodeficiency virus type 1 infection.
Journal of virology 2005;79(9):5705-12.