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Kathleen DePonte

Research Profile

Living Beings

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Chemicals & Drugs

Anatomy

Salivary Glands

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Molecular Sequence Data

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Polymerase Chain Reaction

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Publications

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Tim Schuijt; Alje P Van Dam; Tom van der Poll; Cornelis Van't Veer; Diana Wouters; Mieke Brouwer; Jeroen Coumou; Jianfeng Dai; Kathleen DePonte; Joppe Hovius; Sukanya Narasimhan; Anneke Oei; Joris J T H Roelofs; Erol Fikrig
A tick mannose-binding lectin inhibitor interferes with the vertebrate complement cascade to enhance transmission of the lyme disease agent.
Tim J Schuijt; Sukanya Narasimhan; Sirlei Daffre; Kathleen DePonte; Joppe Hovius; Cornelis Van't Veer; Tom van der Poll; Kamran Bakhtiari; Joost C M Meijers; Eric T Boder; Alje P Van Dam; Erol Fikrig
Identification and characterization of Ixodes scapularis antigens that elicit tick immunity using yeast surface display.
Joao H F Pedra; Sukanya Narasimhan; Dubravko Rendić; Kathleen DePonte; Lesley Bell-Sakyi; Iain Wilson; Erol Fikrig
Fucosylation enhances colonization of ticks by Anaplasma phagocytophilum.

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All Publications

2011: Tim Schuijt; Alje P Van Dam; Tom van der Poll; Cornelis Van't Veer; Diana Wouters; Mieke Brouwer; Jeroen Coumou; Jianfeng Dai; Kathleen DePonte; Joppe Hovius; Sukanya Narasimhan; Anneke Oei; Joris J T H Roelofs; Erol Fikrig
A tick mannose-binding lectin inhibitor interferes with the vertebrate complement cascade to enhance transmission of the lyme disease agent.
Cell host & microbe 2011;10(2):136-46.
2011: Tim J Schuijt; Sukanya Narasimhan; Sirlei Daffre; Kathleen DePonte; Joppe Hovius; Cornelis Van't Veer; Tom van der Poll; Kamran Bakhtiari; Joost C M Meijers; Eric T Boder; Alje P Van Dam; Erol Fikrig
Identification and characterization of Ixodes scapularis antigens that elicit tick immunity using yeast surface display.
PloS one 2011;6(1):e15926.
2010: Joao H F Pedra; Sukanya Narasimhan; Dubravko Rendić; Kathleen DePonte; Lesley Bell-Sakyi; Iain Wilson; Erol Fikrig
Fucosylation enhances colonization of ticks by Anaplasma phagocytophilum.
Cellular microbiology 2010;12(9):1222-34.
2009: Xiuyang Guo; Carmen J Booth; Michael A Paley; Xiaomei Wang; Kathleen DePonte; Erol Fikrig; Sukanya Narasimhan; Ruth R Montgomery
Inhibition of neutrophil function by two tick salivary proteins.
Infection and immunity 2009;77(6):2320-9.
2007: Sukanya Narasimhan; Bindu Sukumaran; Ulas Bozdogan; Venetta Thomas; Xianping Liang; Kathleen DePonte; Nancy Marcantonio; Raymond A Koski; John F Anderson; Fred S Kantor; Erol Fikrig
A tick antioxidant facilitates the Lyme disease agent's successful migration from the mammalian host to the arthropod vector.
Cell host & microbe 2007;2(1):7-18.
2007: G Neelakanta; Xin Li; Utpal Pal; Xianzhong Liu; Deborah S Beck; Kathleen DePonte; Durland Fish; Fred S Kantor; Erol Fikrig
Outer surface protein B is critical for Borrelia burgdorferi adherence and survival within Ixodes ticks.
PLoS pathogens 2007;3(3):e33.
2007: Sukanya Narasimhan; Kathleen DePonte; Nancy Marcantonio; Xianping Liang; Thomas E Royce; Kenneth F Nelson; Carmen J Booth; Benjamin Koski; John F Anderson; Fred S Kantor; Erol Fikrig
Immunity against Ixodes scapularis salivary proteins expressed within 24 hours of attachment thwarts tick feeding and impairs Borrelia transmission.
PloS one 2007;2(5):e451.
2006: Joao H F Pedra; Sukanya Narasimhan; Kathleen DePonte; Nancy Marcantonio; Fred S Kantor; Erol Fikrig
Disruption of the salivary protein 14 in Ixodes scapularis nymphs and impact on pathogen acquisition.
The American journal of tropical medicine and hygiene 2006;75(4):677-82.
2006: Bindu Sukumaran; Sukanya Narasimhan; John F Anderson; Kathleen DePonte; Nancy Marcantonio; Manoj N Krishnan; Durland Fish; Sam R Telford; Fred S Kantor; Erol Fikrig
An Ixodes scapularis protein required for survival of Anaplasma phagocytophilum in tick salivary glands.
The Journal of experimental medicine 2006;203(6):1507-17.
2004: Sukanya Narasimhan; Ruth R Montgomery; Kathleen DePonte; Christian Tschudi; Nancy Marcantonio; John F Anderson; John R Sauer; Michael Cappello; Fred S Kantor; Erol Fikrig
Disruption of Ixodes scapularis anticoagulation by using RNA interference.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(5):1141-6.
2001: Subrata Das; G Banerjee; Kathleen DePonte; Nancy Marcantonio; Fred S Kantor; Erol Fikrig
Salp25D, an Ixodes scapularis antioxidant, is 1 of 14 immunodominant antigens in engorged tick salivary glands.
The Journal of infectious diseases 2001;184(8):1056-64.
2000: Subrata Das; Nancy Marcantonio; Kathleen DePonte; Sam R Telford; John F Anderson; Fred S Kantor; Erol Fikrig
SALP16, a gene induced in Ixodes scapularis salivary glands during tick feeding.
The American journal of tropical medicine and hygiene 2000;62(1):99-105.
1998: S Nazario; Subrata Das; Aravinda Desilva; Kathleen DePonte; Nancy Marcantonio; John F Anderson; Durland Fish; Erol Fikrig; Fred S Kantor
Prevention of Borrelia burgdorferi transmission in guinea pigs by tick immunity.
The American journal of tropical medicine and hygiene 1998;58(6):780-5.
1998: Subrata Das; Kathleen DePonte; Nancy Marcantonio; Jacob W Ijdo; Emir Hodzic; P Katavolos; Stephen W Barthold; Sam R Telford; Fred S Kantor; Erol Fikrig
Granulocytic ehrlichiosis in tick-immune guinea pigs.
Infection and immunity 1998;66(4):1803-5.
1993: Linda K Bockenstedt; Stephen W Barthold; Kathleen DePonte; N Marcantonio; Fred S Kantor
Borrelia burgdorferi infection and immunity in mice deficient in the fifth component of complement.
Infection and immunity 1993;61(5):2104-7.
1992: Erol Fikrig; Stephen W Barthold; N Marcantonio; Kathleen DePonte; Fred S Kantor; Richard A Flavell
Roles of OspA, OspB, and flagellin in protective immunity to Lyme borreliosis in laboratory mice.
Infection and immunity 1992;60(2):657-61.
1991: J E Sears; Erol Fikrig; T Y Nakagawa; Kathleen DePonte; N Marcantonio; Fred S Kantor; Richard A Flavell
Molecular mapping of Osp-A mediated immunity against Borrelia burgdorferi, the agent of Lyme disease.
Journal of immunology (Baltimore, Md. : 1950) 1991;147(6):1995-2000.