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Pascal Derkinderen

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Parkinson's Disease

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Sébastien Paillusson; michel neunlist; Mandy Biraud; Thomas Clairembault; Pascal Derkinderen
Activity-dependent secretion of alpha-synuclein by enteric neurons.
M Tasselli; S Paillusson; P Aubert; T Chaumette; Pascal Derkinderen; Corinne Huchet-Cadiou; Stéphane Hunot; Aude Lafoux; Y Monnet; michel neunlist
Effects of oral administration of rotenone on gastrointestinal functions in mice.
michel neunlist; Pascal Derkinderen; Stanislas Bruley des Varannes; Maxime M Mahé; Laurianne Van Landeghem; Malvyne Rolli-Derkinderen
The digestive neuronal-glial-epithelial unit: a new actor in gut health and disease.

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All Publications

2013: Sébastien Paillusson; michel neunlist; Mandy Biraud; Thomas Clairembault; Pascal Derkinderen
Activity-dependent secretion of alpha-synuclein by enteric neurons.
Journal of neurochemistry 2013;125(4):512-7.
2013: M Tasselli; S Paillusson; P Aubert; T Chaumette; Pascal Derkinderen; Corinne Huchet-Cadiou; Stéphane Hunot; Aude Lafoux; Y Monnet; michel neunlist
Effects of oral administration of rotenone on gastrointestinal functions in mice.
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 2013;25(3):e183-93.
2013: michel neunlist; Pascal Derkinderen; Stanislas Bruley des Varannes; Maxime M Mahé; Laurianne Van Landeghem; Malvyne Rolli-Derkinderen
The digestive neuronal-glial-epithelial unit: a new actor in gut health and disease.
Nature reviews. Gastroenterology & hepatology 2013;10(2):90-100.
2013: David Devos; Bernard Lardeux; Thibaud Lebouvier; Philippe Naveilhan; michel neunlist; Jean-Michel Nguyen; Hélène Pouclet; Tiphaine Rouaud; Mandy Biraud; Stanislas Bruley des Varannes; Emmanuel Coron; Pascal Derkinderen
Colonic inflammation in Parkinson's disease.
Neurobiology of disease 2013;50():42-8.
2013: Hélène Pouclet; Pascal Derkinderen; Thibaud Lebouvier
Foot dystonia heralding levodopa-induced dyskinesias in Parkinson disease.
Clinical neurology and neurosurgery 2013;115(2):235-6.
2012: Hélène Pouclet; Tiphaine Rouaud; Monica Roy; Frédérique Toulgoat; Fabienne Vavasseur; Stanislas Bruley des Varannes; Emmanuel Coron; Mathurin Flamant; Thibaud Lebouvier; michel neunlist; Pascal Derkinderen
Analysis of colonic alpha-synuclein pathology in multiple system atrophy.
Parkinsonism & related disorders 2012;18(7):893-5.
2012: Hélène Pouclet; Emmanuel Coron; Pascal Derkinderen; Mathurin Flamant; Thibaud Lebouvier; michel neunlist; Tiphaine Rouaud
[Autonomic nervous system as a source of biomarkers in Parkinson's disease].
Presse médicale (Paris, France : 1983) 2012;41(7-8):695-701.
2012: Hind Abdo; Kalyane Bach-Ngohou; Pascal Derkinderen; Maxime M Mahé; michel neunlist; Bernard Lardeux
The omega-6 fatty acid derivative 15-deoxy-Δ¹²,¹⁴-prostaglandin J2 is involved in neuroprotection by enteric glial cells against oxidative stress.
The Journal of physiology 2012;590(Pt 11):2739-50.
2012: S Paillusson; H Pouclet; T Lebouvier; michel neunlist; Stanislas Bruley des Varannes; Emmanuel Coron; P Damier; Pascal Derkinderen
[Enteric nervous system and Parkinson's disease].
La Revue de médecine interne / fondée ... par la Société nationale francaise de médecine interne 2012;33(6):335-8.
2012: Hélène Pouclet; Emmanuel Coron; Thibaud Lebouvier; michel neunlist; Pascal Derkinderen
Lewy pathology in gastric and duodenal biopsies in Parkinson's Disease.
Movement disorders : official journal of the Movement Disorder Society 2012;27(6):708.
2012: H Pouclet; Emmanuel Coron; Stanislas Bruley des Varannes; T Lebouvier; michel neunlist; Pascal Derkinderen
A comparison between colonic submucosa and mucosa to detect Lewy pathology in Parkinson's disease.
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 2012;24(4):e202-5.
2012: David R Shprecher; Pascal Derkinderen
Parkinson disease: the enteric nervous system spills its guts.
Neurology 2012;78(9):683; author reply 683.
2012: Claire Meyniel; Pascal Derkinderen; Bernard Giumelli; Philippe Damier
Continuous buccolingual masticatory dyskinesia in Parkinson's disease.
BMJ case reports 2012;2012():.
2012: Claire Boutoleau-Bretonnière; Cédric Bretonnière; Tiphaine Charriau; Philippe Damier; Odile Delaroche; Pascal Derkinderen; Christelle Evrard; Estelle Lamy; Thibaud Lebouvier; Martine Vercelletto
Value of neuropsychological testing, imaging, and CSF biomarkers for the differential diagnosis and prognosis of clinically ambiguous dementia.
Journal of Alzheimer's disease : JAD 2012;28(2):323-36.
2012: Hélène Pouclet; Tiphaine Rouaud; Monica Roy; Stanislas Bruley des Varannes; Emmanuel Coron; Thibaud Lebouvier; michel neunlist; Pascal Derkinderen
A comparison between rectal and colonic biopsies to detect Lewy pathology in Parkinson's disease.
Neurobiology of disease 2012;45(1):305-9.
2011: Pascal Derkinderen; T Lebouvier; michel neunlist; T Rouaud; S Bruley des Varannes; R De Giorgio
Parkinson disease: the enteric nervous system spills its guts.
Neurology 2011;77(19):1761-7.
2011: Alessia Usardi; Brian Anderton; Pascal Derkinderen; Diane P Hanger; Wendy Noble; Amy M Pooler; C Hugh Reynolds; Anjan Seereeram; Ritchie Williamson
Tyrosine phosphorylation of tau regulates its interactions with Fyn SH2 domains, but not SH3 domains, altering the cellular localization of tau.
The FEBS journal 2011;278(16):2927-37.
2011: Christophe Guitton; Patrick Latour; jean-christophe rigal; Ousama Al Habash; David Boutoille; Cédric Bretonniere; Pascal Derkinderen; Laurence Gabillet; Daniel Villers
Propofol Infusion syndrome during refractory status epilepticus in a young adult: successful ECMO resuscitation.
Neurocritical care 2011;15(1):139-45.
2011: Laurianne Van Landeghem; julien Chevalier; Maxime M Mahé; Thilo Wedel; Petri Urvil; Pascal Derkinderen; Tor Savidge; michel neunlist
Enteric glia promote intestinal mucosal healing via activation of focal adhesion kinase and release of proEGF.
American journal of physiology. Gastrointestinal and liver physiology 2011;300(6):G976-87.
2011: Claire Meyniel; Yolaine Ollivier; Mohamed Hamidou; Yann Péréon; Pascal Derkinderen
Dramatic improvement of refractory Isaacs' syndrome after treatment with dronabinol.
Clinical neurology and neurosurgery 2011;113(4):323-4.
2011: Fabienne Clot; David Grabli; Pierre Burbaud; Magali Aya; Pascal Derkinderen; Luc Defebvre; Philippe Damier; Pierre Krystkowiak; Pierre Pollak; Eric LeGuern; Chan San; Agnès Camuzat; Emmanuel Roze; Marie Vidailhet; Alexandra Durr; Alexis Brice
Screening of the THAP1 gene in patients with early-onset dystonia: myoclonic jerks are part of the dystonia 6 phenotype.
Neurogenetics 2011;12(1):87-9.
2011: Timothy Me Scales; Pascal Derkinderen; Kit-Yi Leung; Helen L Byers; Malcolm A Ward; Caroline Price; Ian N Bird; Timothy Perera; Stuart Kellie; Ritchie Williamson; Brian H Anderton; C Hugh Reynolds
Tyrosine phosphorylation of tau by the SRC family kinases lck and fyn.
Molecular neurodegeneration 2011;6():12.
2010: Sébastien Paillusson; Maddalena Tasselli; Thibaud Lebouvier; Maxime Michaël Mahé; julien Chevalier; Mandy Biraud; Chystelle Cario-Toumaniantz; michel neunlist; Pascal Derkinderen
α-Synuclein expression is induced by depolarization and cyclic AMP in enteric neurons.
Journal of neurochemistry 2010;115(3):694-706.
2010: Jean-Sébastien Vidal; Marie Vidailhet; Pascal Derkinderen; Christophe Tzourio; Annick Alpérovitch
Familial aggregation in atypical Parkinson's disease: a case control study in multiple system atrophy and progressive supranuclear palsy.
Journal of neurology 2010;257(8):1388-93.
2010: Rodolphe Soret; julien Chevalier; Pierre De Coppet; Guillaume Poupeau; Pascal Derkinderen; Jean-Pierre Segain; michel neunlist
Short-chain fatty acids regulate the enteric neurons and control gastrointestinal motility in rats.
Gastroenterology 2010;138(5):1772-82.
2010: Hind Abdo; Pascal Derkinderen; Priya Gomes; julien Chevalier; Philippe Aubert; Damien Masson; Jean-Paul Galmiche; Pieter Vanden Berghe; michel neunlist; Bernard Lardeux
Enteric glial cells protect neurons from oxidative stress in part via reduced glutathione.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2010;24(4):1082-94.
2010: Thibaud Lebouvier; Maddalena Tasselli; Sébastien Paillusson; Hélène Pouclet; michel neunlist; Pascal Derkinderen
Biopsable neural tissues: toward new biomarkers for Parkinson's disease?
Frontiers in psychiatry / Frontiers Research Foundation 2010;1():128.
2010: Yulia Worbe; Luc Mallet; Jean-Louis Golmard; Cécile Béhar; Franck Durif; Isabelle Jalenques; Philippe Damier; Pascal Derkinderen; Pierre Pollak; Mathieu Anheim; Emannuel Broussolle; Jing Xie; Valérie Mesnage; Karl Mondon; François Viallet; Pierre Jedynak; Mouna Ben Djebara; Michael Schüpbach; Antoine Pelissolo; Marie Vidailhet; Yves Agid; Jean-Luc Houeto; Andreas Hartmann
Repetitive behaviours in patients with Gilles de la Tourette syndrome: tics, compulsions, or both?
PloS one 2010;5(9):e12959.
2010: Thibaud Lebouvier; michel neunlist; Stanislas Bruley des Varannes; Emmanuel Coron; Anne Drouard; Jean-Michel N'Guyen; Tanguy Chaumette; Maddalena Tasselli; Sébastien Paillusson; Mathurin Flamand; Jean-Paul Galmiche; Philippe Damier; Pascal Derkinderen
Colonic biopsies to assess the neuropathology of Parkinson's disease and its relationship with symptoms.
PloS one 2010;5(9):e12728.
2010: T Lebouvier; E Coron; T Chaumette; S Paillusson; Stanislas Bruley des Varannes; michel neunlist; Pascal Derkinderen
Routine colonic biopsies as a new tool to study the enteric nervous system in living patients.
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 2010;22(1):e11-4.
2009: Jean-Sébastien Vidal; Marie Vidailhet; Pascal Derkinderen; T Dubard de Gaillarbois; Christophe Tzourio; Annick Alpérovitch
Risk factors for progressive supranuclear palsy: a case-control study in France.
Journal of neurology, neurosurgery, and psychiatry 2009;80(11):1271-4.
2009: Thibaud Lebouvier; Tanguy Chaumette; Sébastien Paillusson; Charles Duyckaerts; Stanislas Bruley des Varannes; michel neunlist; Pascal Derkinderen
The second brain and Parkinson's disease.
The European journal of neuroscience 2009;30(5):735-41.
2009: Thibaud Lebouvier; Timothy M E Scales; Ritchie Williamson; Wendy Noble; Charles Duyckaerts; Diane P Hanger; C Hugh Reynolds; Brian H Anderton; Pascal Derkinderen
The microtubule-associated protein tau is also phosphorylated on tyrosine.
Journal of Alzheimer's disease : JAD 2009;18(1):1-9.
2008: Laure Michel; E Auffray-Calvier; Sylvie Raoul; Pascal Derkinderen
Spinal cord compression secondary to extra medullary hematopoiesis.
Clinical neurology and neurosurgery 2008;110(10):1073.
2008: Jean-Sébastien Vidal; Marie Vidailhet; Alexis Elbaz; Pascal Derkinderen; Christophe Tzourio; Annick Alpérovitch
Risk factors of multiple system atrophy: a case-control study in French patients.
Movement disorders : official journal of the Movement Disorder Society 2008;23(6):797-803.
2008: L Michel; Pascal Derkinderen; D Laplaud; B Daumas-Duport; E Auffray-Calvier; T Lebouvier
Emotional facial palsy following striato-capsular infarction.
Journal of neurology, neurosurgery, and psychiatry 2008;79(2):193-4.
2008: Thibaud Lebouvier; Timothy M E Scales; Diane P Hanger; Robert L Geahlen; Bernard Lardeux; C Hugh Reynolds; Brian H Anderton; Pascal Derkinderen
The microtubule-associated protein tau is phosphorylated by Syk.
Biochimica et biophysica acta 2008;1783(2):188-92.
2008: Pascal Derkinderen
[Tourette syndrome: neuropsychiatry is back!].
Presse médicale (Paris, France : 1983) 2008;37(2 Pt 2):260-2.
2006: Philippe Damier; Pascal Derkinderen
[Specificities of the treatment of Parkinson's disease in the elderly].
Psychologie & neuropsychiatrie du vieillissement 2006;4 Spec No 1():S51-9.
2006: Dominique Drapier; Sophie Drapier; Paul Sauleau; Pascal Derkinderen; Philippe Damier; Hervé Allain; Marc Vérin; Bruno Millet
Pathological gambling secondary to dopaminergic therapy in Parkinson's disease.
Psychiatry research 2006;144(2-3):241-4.
2006: C Lanctin; Sandrine Wiertlewski; C Moreau; Christophe Verny; Pascal Derkinderen; Philippe Damier; Frédéric Dubas
[Idiopathic acute transverse myelitis: application of new diagnosis criteria to 17 patients].
Revue neurologique 2006;162(10):980-9.
2005: Pascal Derkinderen; Timothy M E Scales; Diane P Hanger; Kit-Yi Leung; Helen L Byers; Malcolm A Ward; Christof Lenz; Caroline Price; Ian N Bird; Timothy Perera; Stuart Kellie; Ritchie Williamson; Wendy Noble; Richard A Van Etten; Karelle Leroy; Jean-Pierre Brion; C Hugh Reynolds; Brian H Anderton
Tyrosine 394 is phosphorylated in Alzheimer's paired helical filament tau and in fetal tau with c-Abl as the candidate tyrosine kinase.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(28):6584-93.
2005: Stéphane Thobois; Florence Delamarre-Damier; Pascal Derkinderen
Treatment of motor dysfunction in Parkinson's disease: an overview.
Clinical neurology and neurosurgery 2005;107(4):269-81.
2004: Pascal Derkinderen; Emmanuel Valjent; F Darcel; Philippe Damier; Jean-Antoine Girault
[Cannabis and cannabinoid receptors: from pathophysiology to therapeutic options].
Revue neurologique 2004;160(6-7):639-49.
2003: Jean-Sébastien Vidal; Pascal Derkinderen; Marie Vidailhet; Stéphane Thobois; E Broussolle
Mirror movements of the non-affected hand in hemiparkinsonian patients: a reflection of ipsilateral motor overactivity?
Journal of neurology, neurosurgery, and psychiatry 2003;74(9):1352-3.
2003: Pascal Derkinderen; Emmanuel Valjent; Madeleine Toutant; Jean-Christophe Corvol; hervé enslen; Catherine Ledent; James M Trzaskos; Jocelyne Caboche; Jean-Antoine Girault
Regulation of extracellular signal-regulated kinase by cannabinoids in hippocampus.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003;23(6):2371-82.
2002: Pascal Derkinderen; Marie Vidailhet
[Dyskinesia caused by L-DOPA].
Revue neurologique 2002;158 Spec no 1():S92-101.
2002: Pascal Derkinderen; Sophie Dupont; Jean-Sébastien Vidal; François Chedru; Marie Vidailhet
Micrographia secondary to lenticular lesions.
Movement disorders : official journal of the Movement Disorder Society 2002;17(4):835-7.
2001: Pascal Derkinderen; Madeleine Toutant; Gress Kadaré; Catherine Ledent; M Parmentier; Jean-Antoine Girault
Dual role of Fyn in the regulation of FAK+6,7 by cannabinoids in hippocampus.
The Journal of biological chemistry 2001;276(41):38289-96.
2001: P Lavallée; Marie Vidailhet; Jean-Claude Dussaule; Pascal Derkinderen
Post-infectious ophtalmoparesis associated with anti-GM1 but not with anti-GQ1b antibodies.
European journal of neurology : the official journal of the European Federation of Neurological Societies 2001;8(5):475-6.
2001: P Lavallée; Emmanuelle Apartis; Jean-Sébastien Vidal; Marie Vidailhet; Pascal Derkinderen
Acute motor radiculopathy as a first symptom of MS: anatomic-radiologic correlation.
Neurology 2001;56(11):1603-4.
2001: A Peyclit; Hawa Keita; Philippe Juvin; Pascal Derkinderen; F Jardinaud; D Rouellé; Jorge Boczkowski; Jean-Marie Desmonts; Jean-Antoine Girault; Jean Mantz
Effects of riluzole on N-methyl-D-aspartate-induced tyrosine phosphorylation in the rat hippocampus.
Brain research 2001;903(1-2):222-5.
2001: Pascal Derkinderen; Catherine Ledent; M Parmentier; Jean-Antoine Girault
Cannabinoids activate p38 mitogen-activated protein kinases through CB1 receptors in hippocampus.
Journal of neurochemistry 2001;77(3):957-60.
2001: Marie Vidailhet; Pascal Derkinderen; Jean-Sébastien Vidal; Sophie Sangla
[Dystonia of the hand. Semiological analysis and management].
Joint, bone, spine : revue du rhumatisme 2001;68(4):325-8.
2000: Rossella Della Morte; Caterina Squillacioti; Corrado Garbi; Pascal Derkinderen; Maria Antonietta Belisario; Jean-Antoine Girault; Paola Di Natale; Lucio Nitsch; Norma Staiano
Echistatin inhibits pp125FAK autophosphorylation, paxillin phosphorylation and pp125FAK-paxillin interaction in fibronectin-adherent melanoma cells.
European journal of biochemistry / FEBS 2000;267(16):5047-54.
2000: Pascal Derkinderen
[Therapeutic strategies recommended for early stage Parkinson's disease].
Revue neurologique 2000;156 Suppl 2 Pt 2():82-90.
1999: Jean-Antoine Girault; Alicia Costa; Pascal Derkinderen; Jeanne-Marie Studler; Madeleine Toutant
FAK and PYK2/CAKbeta in the nervous system: a link between neuronal activity, plasticity and survival?
Trends in neurosciences 1999;22(6):257-63.
1999: Pascal Derkinderen; hervé enslen; Jean-Antoine Girault
The ERK/MAP-kinases cascade in the nervous system.
Neuroreport 1999;10(5):R24-34.
1998: Pascal Derkinderen; JC Siciliano; Madeleine Toutant; Jean-Antoine Girault
Differential regulation of FAK+ and PYK2/Cakbeta, two related tyrosine kinases, in rat hippocampal slices: effects of LPA, carbachol, depolarization and hyperosmolarity.
The European journal of neuroscience 1998;10(5):1667-75.
1996: J C Siciliano; Madeleine Toutant; Pascal Derkinderen; T Sasaki; Jean-Antoine Girault
Differential regulation of proline-rich tyrosine kinase 2/cell adhesion kinase beta (PYK2/CAKbeta) and pp125(FAK) by glutamate and depolarization in rat hippocampus.
The Journal of biological chemistry 1996;271(46):28942-6.
1996: Pascal Derkinderen; Madeleine Toutant; Ferran Burgaya; M Le Bert; J C Siciliano; V de Franciscis; M Gelman; Jean-Antoine Girault
Regulation of a neuronal form of focal adhesion kinase by anandamide.
Science (New York, N.Y.) 1996;273(5282):1719-22.