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Peter Dervan

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Co-Publications
Name
21
Gottesfeld, Joel
13
Melander, Christian
9
Baird, Eldon
9
Baird, EE
9
Ansari, Aseem
8
Chenoweth, David
8
Trauger, JW
7
Wurtz, Nicholas
7
Foister, Shane
7
Nickols, Nicholas
6
Marques, Michael
6
Dickinson, Liliane
6
Doss, Raymond
6
Farkas, Michelle
6
Wold, Barbara

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Publications

TOP 3
Muzikar Katy A; Nickols Nicholas G; Dervan Peter B
Repression of DNA-binding dependent glucocorticoid receptor-mediated gene expression.
Chenoweth David M; Dervan Peter B
Allosteric modulation of DNA by small molecules.
Chenoweth David M; Harki Daniel A; Dervan Peter B
Oligomerization route to Py-Im polyamide macrocycles.

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All Publications

2009: Muzikar Katy A; Nickols Nicholas G; Dervan Peter B
Repression of DNA-binding dependent glucocorticoid receptor-mediated gene expression.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(39):16598-603.
2009: Chenoweth David M; Dervan Peter B
Allosteric modulation of DNA by small molecules.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(32):13175-9.
2009: Chenoweth David M; Harki Daniel A; Dervan Peter B
Oligomerization route to Py-Im polyamide macrocycles.
Organic letters 2009;11(16):3590-3.
2009: Farkas Michelle E; Li Benjamin C; Dose Christian; Dervan Peter B
DNA sequence selectivity of hairpin polyamide turn units.
Bioorganic & medicinal chemistry letters 2009;19(14):3919-23.
2009: Chenoweth David M; Harki Daniel A; Dervan Peter B
Solution-phase synthesis of pyrrole-imidazole polyamides.
Journal of the American Chemical Society 2009;131(20):7175-81.
2009: Chenoweth David M; Harki Daniel A; Phillips John W; Dose Christian; Dervan Peter B
Cyclic pyrrole-imidazole polyamides targeted to the androgen response element.
Journal of the American Chemical Society 2009;131(20):7182-8.
2008: Hsu Carey F; Dervan Peter B
Quantitating the concentration of Py-Im polyamide-fluorescein conjugates in live cells.
Bioorganic & medicinal chemistry letters 2008;18(22):5851-5.
2008: Harki Daniel A; Satyamurthy Nagichettiar; Stout David B; Phelps Michael E; Dervan Peter B
In vivo imaging of pyrrole-imidazole polyamides with positron emission tomography.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(35):13039-44.
2008: Dose Christian; Farkas Michelle E; Chenoweth David M; Dervan Peter B
Next generation hairpin polyamides with (R)-3,4-diaminobutyric acid turn unit.
Journal of the American Chemical Society 2008;130(21):6859-66.
2008: Moretti Rocco; Donato Leslie J; Brezinski Mary L; Stafford Ryan L; Hoff Helena; Thorson Jon S; Dervan Peter B; Ansari Aseem Z
Targeted chemical wedges reveal the role of allosteric DNA modulation in protein-DNA assembly.
ACS chemical biology 2008;3(4):220-9.
2008: Chou C James; Farkas Michelle E; Tsai Sherry M; Alvarez David; Dervan Peter B; Gottesfeld Joel M
Small molecules targeting histone H4 as potential therapeutics for chronic myelogenous leukemia.
Molecular cancer therapeutics 2008;7(4):769-78.
2008: Cohen Justin D; Sadowski John P; Dervan Peter B
Programming multiple protein patterns on a single DNA nanostructure.
Journal of the American Chemical Society 2008;130(2):402-3.
2007: Stafford Ryan L; Dervan Peter B
The reach of linear protein-DNA dimerizers.
Journal of the American Chemical Society 2007;129(45):14026-33.
2007: Farkas Michelle E; Tsai Sherry M; Dervan Peter B
Alpha-diaminobutyric acid-linked hairpin polyamides.
Bioorganic & medicinal chemistry 2007;15(22):6927-36.
2007: Puckett James W; Muzikar Katy A; Tietjen Josh; Warren Christopher L; Ansari Aseem Z; Dervan Peter B
Quantitative microarray profiling of DNA-binding molecules.
Journal of the American Chemical Society 2007;129(40):12310-9.
2007: Nickols Nicholas G; Jacobs Claire S; Farkas Michelle E; Dervan Peter B
Modulating hypoxia-inducible transcription by disrupting the HIF-1-DNA interface.
ACS chemical biology 2007;2(8):561-71.
2007: Nickols Nicholas G; Dervan Peter B
Suppression of androgen receptor-mediated gene expression by a sequence-specific DNA-binding polyamide.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(25):10418-23.
2007: Stafford Ryan L; Arndt Hans-Dieter; Brezinski Mary L; Ansari Aseem Z; Dervan Peter B
Minimization of a protein-DNA dimerizer.
Journal of the American Chemical Society 2007;129(9):2660-8.
2007: Chenoweth David M; Viger Anne; Dervan Peter B
Fluorescent sequence-specific dsDNA binding oligomers.
Journal of the American Chemical Society 2007;129(8):2216-7.
2007: Chenoweth David M; Poposki Julie A; Marques Michael A; Dervan Peter B
Programmable oligomers targeting 5'-GGGG-3' in the minor groove of DNA and NF-kappaB binding inhibition.
Bioorganic & medicinal chemistry 2007;15(2):759-70.
2007: Dose Christian; Ho Dominik; Gaub Hermann E; Dervan Peter B; Albrecht Christian H
Recognition of "mirror-image" DNA by small molecules.
Angewandte Chemie (International ed. in English) 2007;46(44):8384-7.
2007: Cohen Justin D; Sadowski John P; Dervan Peter B
Addressing single molecules on DNA nanostructures.
Angewandte Chemie (International ed. in English) 2007;46(42):7956-9.
2007: Nickols Nicholas G; Jacobs Claire S; Farkas Michelle E; Dervan Peter B
Improved nuclear localization of DNA-binding polyamides.
Nucleic acids research 2007;35(2):363-70.
2007: Tsai Sherry M; Farkas Michelle E; Chou C James; Gottesfeld Joel M; Dervan Peter B
Unanticipated differences between alpha- and gamma-diaminobutyric acid-linked hairpin polyamide-alkylator conjugates.
Nucleic acids research 2007;35(1):307-16.
2006: Viger Anne; Dervan Peter B
Exploring the limits of benzimidazole DNA-binding oligomers for the hypoxia inducible factor (HIF) site.
Bioorganic & medicinal chemistry 2006;14(24):8539-49.
2006: Burnett Ryan; Melander Christian; Puckett James W; Son Leslie S; Wells Robert D; Dervan Peter B; Gottesfeld Joel M
DNA sequence-specific polyamides alleviate transcription inhibition associated with long GAA.TTC repeats in Friedreich's ataxia.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(31):11497-502.
2006: Alvarez David; Chou C James; Latella Lucia; Zeitlin Samantha G; Ku Sherman; Puri Pier Lorenzo; Dervan Peter B; Gottesfeld Joel M
A two-hit mechanism for pre-mitotic arrest of cancer cell proliferation by a polyamide-alkylator conjugate.
Cell cycle (Georgetown, Tex.) 2006;5(14):1537-48.
2006: Doss Raymond M; Marques Michael A; Foister Shane; Chenoweth David M; Dervan Peter B
Programmable oligomers for minor groove DNA recognition.
Journal of the American Chemical Society 2006;128(28):9074-9.
2006: Warren Christopher L; Kratochvil Natasha C S; Hauschild Karl E; Foister Shane; Brezinski Mary L; Dervan Peter B; Phillips George N; Ansari Aseem Z
Defining the sequence-recognition profile of DNA-binding molecules.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(4):867-72.
2005: Fechter Eric J; Olenyuk Bogdan; Dervan Peter B
Sequence-specific fluorescence detection of DNA by polyamide-thiazole orange conjugates.
Journal of the American Chemical Society 2005;127(47):16685-91.
2005: Dervan Peter B; Doss Raymond M; Marques Michael A
Programmable DNA binding oligomers for control of transcription.
Current medicinal chemistry. Anti-cancer agents 2005;5(4):373-87.
2005: Hauschild Karl E; Metzler Renee E; Arndt Hans-Dieter; Moretti Rocco; Raffaelle Marni; Dervan Peter B; Ansari Aseem Z
Temperature-sensitive protein-DNA dimerizers.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(14):5008-13.
2005: Gearhart Micah D; Dickinson Liliane; Ehley Jennifer; Melander Christian; Dervan Peter B; Wright Peter E; Gottesfeld Joel M
Inhibition of DNA binding by human estrogen-related receptor 2 and estrogen receptor alpha with minor groove binding polyamides.
Biochemistry 2005;44(11):4196-203.
2005: Philips Brian J; Chang Aileen Y; Dervan Peter B; Beerman Terry A
DNA damage effects of a polyamide-CBI conjugate in SV40 virions.
Molecular pharmacology 2005;67(3):877-82.
2005: Edayathumangalam Rajeswari S; Weyermann Philipp; Dervan Peter B; Gottesfeld Joel M; Luger Karolin
Nucleosomes in solution exist as a mixture of twist-defect states.
Journal of molecular biology 2005;345(1):103-14.
2004: Olenyuk Bogdan Z; Zhang Guo-Jun; Klco Jeffery M; Nickols Nicholas G; Kaelin William G; Dervan Peter B
Inhibition of vascular endothelial growth factor with a sequence-specific hypoxia response element antagonist.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(48):16768-73.
2004: Dickinson Liliane A; Burnett Ryan; Melander Christian; Edelson Benjamin S; Arora Paramjit S; Dervan Peter B; Gottesfeld Joel M
Arresting cancer proliferation by small-molecule gene regulation.
Chemistry & biology 2004;11(11):1583-94.
2004: Ylisastigui Loyda; Coull Jason J; Rucker Victor C; Melander Christian; Bosch Ronald J; Brodie Scott J; Corey Lawrence; Sodora Donald L; Dervan Peter B; Margolis David M
Polyamides reveal a role for repression in latency within resting T cells of HIV-infected donors.
The Journal of infectious diseases 2004;190(8):1429-37.
2004: Livengood Jill A; Fechter Eric J; Dervan Peter B; Nyborg Jennifer K
Paradoxical effects of DNA binding polyamides on HTLV-1 transcription.
Frontiers in bioscience : a journal and virtual library 2004;9():3058-67.
2004: Marques Michael A; Doss Raymond M; Foister Shane; Dervan Peter B
Expanding the repertoire of heterocycle ring pairs for programmable minor groove DNA recognition.
Journal of the American Chemical Society 2004;126(33):10339-49.
2004: Fechter Eric J; Olenyuk Bogdan; Dervan Peter B
Design of a sequence-specific DNA bisintercalator.
Angewandte Chemie (International ed. in English) 2004;43(27):3591-4.
2004: Doss Raymond M; Marques Michael A; Foister Shane; Dervan Peter B
DNA minor-groove recognition by 3-methylthiophene/pyrrole pair.
Chemistry & biodiversity 2004;1(6):886-99.
2004: Edayathumangalam Rajeswari S; Weyermann Philipp; Gottesfeld Joel M; Dervan Peter B; Luger Karolin
Molecular recognition of the nucleosomal "supergroove".
Proceedings of the National Academy of Sciences of the United States of America 2004;101(18):6864-9.
2004: Nguyen-Hackley Doan H; Ramm Elizabeth; Taylor Christina M; Joung J Keith; Dervan Peter B; Pabo Carl O
Allosteric inhibition of zinc-finger binding in the major groove of DNA by minor-groove binding ligands.
Biochemistry 2004;43(13):3880-90.
2004: Edelson Benjamin S; Best Timothy P; Olenyuk Bogdan; Nickols Nicholas G; Doss Raymond M; Foister Shane; Heckel Alexander; Dervan Peter B
Influence of structural variation on nuclear localization of DNA-binding polyamide-fluorophore conjugates.
Nucleic acids research 2004;32(9):2802-18.
2003: Poulin-Kerstien Adam T; Dervan Peter B
DNA-templated dimerization of hairpin polyamides.
Journal of the American Chemical Society 2003;125(51):15811-21.
2003: Arndt Hans-Dieter; Hauschild Karl E; Sullivan David P; Lake Kara; Dervan Peter B; Ansari Aseem Z
Toward artificial developmental regulators.
Journal of the American Chemical Society 2003;125(44):13322-3.
2003: Best Timothy P; Edelson Benjamin S; Nickols Nicholas G; Dervan Peter B
Nuclear localization of pyrrole-imidazole polyamide-fluorescein conjugates in cell culture.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(21):12063-8.
2003: Foister Shane; Marques Michael A; Doss Raymond M; Dervan Peter B
Shape selective recognition of T.A base pairs by hairpin polyamides containing N-terminal 3-methoxy (and 3-chloro) thiophene residues.
Bioorganic & medicinal chemistry 2003;11(20):4333-40.
2003: Dudouet Brigitte; Burnett Ryan; Dickinson Liliane A; Wood Malcolm R; Melander Christian; Belitsky Jason M; Edelson Benjamin; Wurtz Nicholas; Briehn Christoph; Dervan Peter B; Gottesfeld Joel M
Accessibility of nuclear chromatin by DNA binding polyamides.
Chemistry & biology 2003;10(9):859-67.
2003: Heckel Alexander; Dervan Peter B
U-pin polyamide motif for recognition of the DNA minor groove.
Chemistry (Weinheim an der Bergstrasse, Germany) 2003;9(14):3353-66.
2003: Fechter Eric J; Dervan Peter B
Allosteric inhibition of protein--DNA complexes by polyamide--intercalator conjugates.
Journal of the American Chemical Society 2003;125(28):8476-85.
2003: Dervan Peter B; Edelson Benjamin S
Recognition of the DNA minor groove by pyrrole-imidazole polyamides.
Current opinion in structural biology 2003;13(3):284-99.
2003: Yang Fan; Belitsky Jason M; Villanueva Rodrigo A; Dervan Peter B; Roth Monica J
Inhibition of Moloney murine leukemia virus integration using polyamides targeting the long-terminal repeat sequences.
Biochemistry 2003;42(20):6249-58.
2003: Briehn Christoph A; Weyermann Philipp; Dervan Peter B
Alternative heterocycles for DNA recognition: the benzimidazole/imidazole pair.
Chemistry (Weinheim an der Bergstrasse, Germany) 2003;9(9):2110-22.
2003: Renneberg Dorte; Dervan Peter B
Imidazopyridine/Pyrrole and hydroxybenzimidazole/pyrrole pairs for DNA minor groove recognition.
Journal of the American Chemical Society 2003;125(19):5707-16.
2003: Olenyuk Bogdan; Jitianu Cristian; Dervan Peter B
Parallel synthesis of H-pin polyamides by alkene metathesis on solid phase.
Journal of the American Chemical Society 2003;125(16):4741-51.
2003: Wang Yong-Dong; Dziegielewski Jaroslaw; Wurtz Nicholas R; Dziegielewska Barbara; Dervan Peter B; Beerman Terry A
DNA crosslinking and biological activity of a hairpin polyamide-chlorambucil conjugate.
Nucleic acids research 2003;31(4):1208-15.
2003: Suto Robert K; Edayathumangalam Rajeswari S; White Cindy L; Melander Christian; Gottesfeld Joel M; Dervan Peter B; Luger Karolin
Crystal structures of nucleosome core particles in complex with minor groove DNA-binding ligands.
Journal of molecular biology 2003;326(2):371-80.
2003: Rucker Victor C; Foister Shane; Melander Christian; Dervan Peter B
Sequence specific fluorescence detection of double strand DNA.
Journal of the American Chemical Society 2003;125(5):1195-202.
2002: Coull Jason J; He Guocheng; Melander Christian; Rucker Victor C; Dervan Peter B; Margolis David M
Targeted derepression of the human immunodeficiency virus type 1 long terminal repeat by pyrrole-imidazole polyamides.
Journal of virology 2002;76(23):12349-54.
2002: Arora Paramjit S; Ansari Aseem Z; Best Timothy P; Ptashne Mark; Dervan Peter B
Design of artificial transcriptional activators with rigid poly-L-proline linkers.
Journal of the American Chemical Society 2002;124(44):13067-71.
2002: Wang Yong-Dong; Dziegielewski Jaroslaw; Chang Aileen Y; Dervan Peter B; Beerman Terry A
Cell-free and cellular activities of a DNA sequence selective hairpin polyamide-CBI conjugate.
The Journal of biological chemistry 2002;277(45):42431-7.
2002: Kers Inger; Dervan Peter B
Search for the optimal linker in tandem hairpin polyamides.
Bioorganic & medicinal chemistry 2002;10(10):3339-49.
2002: Belitsky Jason M; Leslie Stephanie J; Arora Paramjit S; Beerman Terry A; Dervan Peter B
Cellular uptake of N-methylpyrrole/N-methylimidazole polyamide-dye conjugates.
Bioorganic & medicinal chemistry 2002;10(10):3313-8.
2002: Gottesfeld Joel M; Belitsky Jason M; Melander Christian; Dervan Peter B; Luger Karolin
Blocking transcription through a nucleosome with synthetic DNA ligands.
Journal of molecular biology 2002;321(2):249-63.
2002: Belitsky J M; Nguyen D H; Wurtz N R; Dervan Peter B
Solid-phase synthesis of DNA binding polyamides on oxime resin.
Bioorganic & medicinal chemistry 2002;10(8):2767-74.
2002: Urbach Adam R; Love John J; Ross Scott A; Dervan Peter B
Structure of a beta-alanine-linked polyamide bound to a full helical turn of purine tract DNA in the 1:1 motif.
Journal of molecular biology 2002;320(1):55-71.
2002: Weyermann Philipp; Dervan Peter B
Recognition of ten base pairs of DNA by head-to-head hairpin dimers.
Journal of the American Chemical Society 2002;124(24):6872-8.
2002: Wurtz Nicholas R; Pomerantz Joel L; Baltimore David; Dervan Peter B
Inhibition of DNA binding by NF-kappa B with pyrrole-imidazole polyamides.
Biochemistry 2002;41(24):7604-9.
2002: Ehley Jennifer A; Melander Christian; Herman David; Baird Eldon E; Ferguson Heather A; Goodrich James A; Dervan Peter B; Gottesfeld Joel M
Promoter scanning for transcription inhibition with DNA-binding polyamides.
Molecular and cellular biology 2002;22(6):1723-33.
2001: Dervan P B
Molecular recognition of DNA by small molecules.
Bioorganic & medicinal chemistry 2001;9(9):2215-35.
2001: Wang C C; Dervan P B
Sequence-specific trapping of topoisomerase I by DNA binding polyamide-camptothecin conjugates.
Journal of the American Chemical Society 2001;123(36):8657-61.
2001: Bremer R E; Wurtz N R; Szewczyk J W; Dervan P B
Inhibition of major groove DNA binding bZIP proteins by positive patch polyamides.
Bioorganic & medicinal chemistry 2001;9(8):2093-103.
2001: Ansari A Z; Mapp A K; Nguyen D H; Dervan P B; Ptashne M
Towards a minimal motif for artificial transcriptional activators.
Chemistry & biology 2001;8(6):583-92.
2001: Gottesfeld J M; Melander C; Suto R K; Raviol H; Luger K; Dervan P B
Sequence-specific recognition of DNA in the nucleosome by pyrrole-imidazole polyamides.
Journal of molecular biology 2001;309(3):615-29.
2001: Wurtz N R; Turner J M; Baird E E; Dervan P B
Fmoc solid phase synthesis of polyamides containing pyrrole and imidazole amino acids.
Organic letters 2001;3(8):1201-3.
2001: Urbach A R; Dervan P B
Toward rules for 1:1 polyamide:DNA recognition.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(8):4343-8.
2001: Wang C C; Ellervik U; Dervan P B
Expanding the recognition of the minor groove of DNA by incorporation of beta-alanine in hairpin polyamides.
Bioorganic & medicinal chemistry 2001;9(3):653-7.
2001: Nguyen D H; Szewczyk J W; Baird E E; Dervan P B
Alternative heterocycles for DNA recognition: an N-methylpyrazole/N-methylpyrrole pair specifies for A.T/T.A base pairs.
Bioorganic & medicinal chemistry 2001;9(1):7-17.
2001: Baliga R; Baird E E; Herman D M; Melander C; Dervan P B; Crothers D M
Kinetic consequences of covalent linkage of DNA binding polyamides.
Biochemistry 2001;40(1):3-8.
2001: Trauger J W; Dervan P B
Footprinting methods for analysis of pyrrole-imidazole polyamide/DNA complexes.
Methods in enzymology 2001;340():450-66.
2000: Melander C; Herman D M; Dervan P B
Discrimination of A/T sequences in the minor groove of DNA within a cyclic polyamide motif.
Chemistry (Weinheim an der Bergstrasse, Germany) 2000;6(24):4487-97.
2000: Zhan Z Y; Dervan P B
Alternative heterocycles for DNA recognition: a 3-pyrazole/pyrrole pair specifies for G.C base pairs.
Bioorganic & medicinal chemistry 2000;8(10):2467-74.
2000: Bremer R E; Szewczyk J W; Baird E E; Dervan P B
Recognition of the DNA minor groove by pyrrole-imidazole polyamides: comparison of desmethyl- and N-methylpyrrole.
Bioorganic & medicinal chemistry 2000;8(8):1947-55.
2000: Winston R L; Ehley J A; Baird E E; Dervan P B; Gottesfeld J M
Asymmetric DNA binding by a homodimeric bHLH protein.
Biochemistry 2000;39(31):9092-8.
2000: Chiang S Y; Burli R W; Benz C C; Gawron L; Scott G K; Dervan P B; Beerman T A
Targeting the ets binding site of the HER2/neu promoter with pyrrole-imidazole polyamides.
The Journal of biological chemistry 2000;275(32):24246-54.
2000: Mapp A K; Ansari A Z; Ptashne M; Dervan P B
Activation of gene expression by small molecule transcription factors.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(8):3930-5.
2000: Wurtz N R; Dervan P B
Sequence specific alkylation of DNA by hairpin pyrrole-imidazole polyamide conjugates.
Chemistry & biology 2000;7(3):153-61.
2000: Kielkopf C L; Bremer R E; White S; Szewczyk J W; Turner J M; Baird E E; Dervan P B; Rees D C
Structural effects of DNA sequence on T.A recognition by hydroxypyrrole/pyrrole pairs in the minor groove.
Journal of molecular biology 2000;295(3):557-67.
2000: Gottesfeld J M; Turner J M; Dervan P B
Chemical approaches to control gene expression.
Gene expression 2000;9(1-2):77-91.
1999: Dervan P B; Bürli R W
Sequence-specific DNA recognition by polyamides.
Current opinion in chemical biology 1999;3(6):688-93.
1999: Lenzmeier B A; Baird E E; Dervan P B; Nyborg J K
The tax protein-DNA interaction is essential for HTLV-I transactivation in vitro.
Journal of molecular biology 1999;291(4):731-44.
1999: Dickinson L A; Trauger J W; Baird E E; Ghazal P; Dervan P B; Gottesfeld J M
Anti-repression of RNA polymerase II transcription by pyrrole-imidazole polyamides.
Biochemistry 1999;38(33):10801-7.
1999: Dickinson L A; Trauger J W; Baird E E; Dervan P B; Graves B J; Gottesfeld J M
Inhibition of Ets-1 DNA binding and ternary complex formation between Ets-1, NF-kappaB, and DNA by a designed DNA-binding ligand.
The Journal of biological chemistry 1999;274(18):12765-73.
1999: McBryant S J; Baird E E; Trauger J W; Dervan P B; Gottesfeld J M
Minor groove DNA-protein contacts upstream of a tRNA gene detected with a synthetic DNA binding ligand.
Journal of molecular biology 1999;286(4):973-81.
1999: Pilch D S; Poklar N; Baird E E; Dervan P B; Breslauer K J
The thermodynamics of polyamide-DNA recognition: hairpin polyamide binding in the minor groove of duplex DNA.
Biochemistry 1999;38(7):2143-51.
1998: Dickinson L A; Gulizia R J; Trauger J W; Baird E E; Mosier D E; Gottesfeld J M; Dervan P B
Inhibition of RNA polymerase II transcription in human cells by synthetic DNA-binding ligands.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(22):12890-5.
1998: Kielkopf C L; White S; Szewczyk J W; Turner J M; Baird E E; Dervan P B; Rees D C
A structural basis for recognition of A.T and T.A base pairs in the minor groove of B-DNA.
Science (New York, N.Y.) 1998;282(5386):111-5.
1998: Bremer R E; Baird E E; Dervan P B
Inhibition of major-groove-binding proteins by pyrrole-imidazole polyamides with an Arg-Pro-Arg positive patch.
Chemistry & biology 1998;5(3):119-33.
1998: Kielkopf C L; Baird E E; Dervan P B; Rees D C
Structural basis for G.C recognition in the DNA minor groove.
Nature structural biology 1998;5(2):104-9.
1998: White S; Szewczyk J W; Turner J M; Baird E E; Dervan P B
Recognition of the four Watson-Crick base pairs in the DNA minor groove by synthetic ligands.
Nature 1998;391(6666):468-71.
1997: Neely L; Trauger J W; Baird E E; Dervan P B; Gottesfeld J M
Importance of minor groove binding zinc fingers within the transcription factor IIIA-DNA complex.
Journal of molecular biology 1997;274(4):439-45.
1997: White S; Baird E E; Dervan P B
On the pairing rules for recognition in the minor groove of DNA by pyrrole-imidazole polyamides.
Chemistry & biology 1997;4(8):569-78.
1997: Taylor M J; Dervan P B
Kinetic analysis of sequence-specific alkylation of DNA by pyrimidine oligodeoxyribonucleotide-directed triple-helix formation.
Bioconjugate chemistry 1997;8(3):354-64.
1997: Gottesfeld J M; Neely L; Trauger J W; Baird E E; Dervan P B
Regulation of gene expression by small molecules.
Nature 1997;387(6629):202-5.
1996: White S; Baird E E; Dervan P B
Effects of the A.T/T.A degeneracy of pyrrole--imidazole polyamide recognition in the minor groove of DNA.
Biochemistry 1996;35(38):12532-7.
1996: Grant K B; Dervan P B
Sequence-specific alkylation and cleavage of DNA mediated by purine motif triple helix formation.
Biochemistry 1996;35(38):12313-9.
1996: Liberles D A; Dervan P B
Design of artificial sequence-specific DNA bending ligands.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(18):9510-4.
1996: Trauger J W; Baird E E; Dervan P B
Recognition of DNA by designed ligands at subnanomolar concentrations.
Nature 1996;382(6591):559-61.
1996: Parks M E; Dervan P B
Simultaneous binding of a polyamide dimer and an oligonucleotide in the minor and major grooves of DNA.
Bioorganic & medicinal chemistry 1996;4(7):1045-50.
1996: Kelly J J; Baird E E; Dervan P B
Binding site size limit of the 2:1 pyrrole-imidazole polyamide-DNA motif.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(14):6981-5.
1996: Brunar H; Dervan P B
Sequence composition effects on the stabilities of triple helix formation by oligonucleotides containing N7-deoxyguanosine.
Nucleic acids research 1996;24(11):1987-91.
1996: Trauger J W; Baird E E; Dervan P B
Extended hairpin polyamide motif for sequence-specific recognition in the minor groove of DNA.
Chemistry & biology 1996;3(5):369-77.
1996: Wang E; Koshlap K M; Gillespie P; Dervan P B; Feigon J
Solution structure of a pyrimidine-purine-pyrimidine triplex containing the sequence-specific intercalating non-natural base D3.
Journal of molecular biology 1996;257(5):1052-69.
1996: Geierstanger B H; Mrksich M; Dervan P B; Wemmer D E
Extending the recognition site of designed minor groove binding molecules.
Nature structural biology 1996;3(4):321-4.
1995: Baliga R; Singleton J W; Dervan P B
RecA.oligonucleotide filaments bind in the minor groove of double-stranded DNA.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(22):10393-7.
1995: Cho J; Parks M E; Dervan P B
Cyclic polyamides for recognition in the minor groove of DNA.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(22):10389-92.
1994: Geierstanger B H; Mrksich M; Dervan P B; Wemmer D E
Design of a G.C-specific DNA minor groove-binding peptide.
Science (New York, N.Y.) 1994;266(5185):646-50.
1994: Han H; Schepartz A; Pellegrini M; Dervan P B
Mapping RNA regions in eukaryotic ribosomes that are accessible to methidiumpropyl-EDTA.Fe(II) and EDTA.Fe(II).
Biochemistry 1994;33(33):9831-44.
1994: Staubli A B; Dervan P B
Sequence specificity of the non-natural pyrido[2,3-d]pyrimidine nucleoside in triple helix formation.
Nucleic acids research 1994;22(13):2637-42.
1994: Han H; Dervan P B
Different conformational families of pyrimidine.purine.pyrimidine triple helices depending on backbone composition.
Nucleic acids research 1994;22(14):2837-44.
1994: Han H; Dervan P B
Visualization of RNA tertiary structure by RNA-EDTA.Fe(II) autocleavage: analysis of tRNA(Phe) with uridine-EDTA.Fe(II) at position 47.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(11):4955-9.
1994: Hacia J G; Dervan P B; Wold B J
Inhibition of Klenow fragment DNA polymerase on double-helical templates by oligonucleotide-directed triple-helix formation.
Biochemistry 1994;33(20):6192-200.
1994: Hacia J G; Wold B J; Dervan P B
Phosphorothioate oligonucleotide-directed triple helix formation.
Biochemistry 1994;33(18):5367-9.
1994: Oakley M G; Turnbull K D; Dervan P B
Synthesis of a hybrid protein containing the iron-binding ligand of bleomycin and the DNA-binding domain of Hin.
Bioconjugate chemistry 1994;5(3):242-7.
1994: Geierstanger B H; Jacobsen J P; Mrksich M; Dervan P B; Wemmer D E
Structural and dynamic characterization of the heterodimeric and homodimeric complexes of distamycin and 1-methylimidazole-2-carboxamide-netropsin bound to the minor groove of DNA.
Biochemistry 1994;33(10):3055-62.
1993: Singleton S F; Dervan P B
Equilibrium association constants for oligonucleotide-directed triple helix formation at single DNA sites: linkage to cation valence and concentration.
Biochemistry 1993;32(48):13171-9.
1993: Wade W S; Mrksich M; Dervan P B
Binding affinities of synthetic peptides, pyridine-2-carboxamidonetropsin and 1-methylimidazole-2-carboxamidonetropsin, that form 2:1 complexes in the minor groove of double-helical DNA.
Biochemistry 1993;32(42):11385-9.
1993: Feng J A; Simon M; Mack D P; Dervan P B; Johnson R C; Dickerson R E
Crystallization and preliminary X-ray analysis of the DNA binding domain of the Hin recombinase with its DNA binding site.
Journal of molecular biology 1993;232(3):982-6.
1993: Han H; Dervan P B
Sequence-specific recognition of double helical RNA and RNA.DNA by triple helix formation.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(9):3806-10.
1993: Stilz H U; Dervan P B
Specific recognition of CG base pairs by 2-deoxynebularine within the purine.purine.pyrimidine triple-helix motif.
Biochemistry 1993;32(9):2177-85.
1993: Distefano M D; Dervan P B
Energetics of cooperative binding of oligonucleotides with discrete dimerization domains to DNA by triple helix formation.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(4):1179-83.
1993: Iverson B L; Dervan P B
Adenine-specific DNA chemical sequencing reaction.
Methods in enzymology 1993;218():222-7.
1992: Singleton S F; Dervan P B
Influence of pH on the equilibrium association constants for oligodeoxyribonucleotide-directed triple helix formation at single DNA sites.
Biochemistry 1992;31(45):10995-1003.
1992: Oakley M G; Mrksich M; Dervan P B
Evidence that a minor groove-binding peptide and a major groove-binding protein can simultaneously occupy a common site on DNA.
Biochemistry 1992;31(45):10969-75.
1992: Mack D P; Dervan P B
Sequence-specific oxidative cleavage of DNA by a designed metalloprotein, Ni(II).GGH(Hin139-190).
Biochemistry 1992;31(39):9399-405.
1992: Dervan P B
Reagents for the site-specific cleavage of megabase DNA.
Nature 1992;359(6390):87-8.
1992: Mrksich M; Wade W S; Dwyer T J; Geierstanger B H; Wemmer D E; Dervan P B
Antiparallel side-by-side dimeric motif for sequence-specific recognition in the minor groove of DNA by the designed peptide 1-methylimidazole-2-carboxamide netropsin.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(16):7586-90.
1992: Luebke K J; Dervan P B
Nonenymatic ligation of double-helical DNA by alternate-strand triple helix formation.
Nucleic acids research 1992;20(12):3005-9.
1992: Beal P A; Dervan P B
The influence of single base triplet changes on the stability of a pur.pur.pyr triple helix determined by affinity cleaving.
Nucleic acids research 1992;20(11):2773-6.
1992: Kiessling L L; Griffin L C; Dervan P B
Flanking sequence effects within the pyrimidine triple-helix motif characterized by affinity cleaving.
Biochemistry 1992;31(10):2829-34.
1992: Maher L J; Dervan P B; Wold B
Analysis of promoter-specific repression by triple-helical DNA complexes in a eukaryotic cell-free transcription system.
Biochemistry 1992;31(1):70-81.
1992: Strobel S A; Dervan P B
Triple helix-mediated single-site enzymatic cleavage of megabase genomic DNA.
Methods in enzymology 1992;216():309-21.
1991: Strobel S A; Doucette-Stamm L A; Riba L; Housman D E; Dervan P B
Site-specific cleavage of human chromosome 4 mediated by triple-helix formation.
Science (New York, N.Y.) 1991;254(5038):1639-42.
1991: Shin J A; Ebright R H; Dervan P B
Orientation of the Lac repressor DNA binding domain in complex with the left lac operator half site characterized by affinity cleaving.
Nucleic acids research 1991;19(19):5233-6.
1991: Horne D A; Dervan P B
Effects of an abasic site on triple helix formation characterized by affinity cleaving.
Nucleic acids research 1991;19(18):4963-5.
1991: Beal P A; Dervan P B
Second structural motif for recognition of DNA by oligonucleotide-directed triple-helix formation.
Science (New York, N.Y.) 1991;251(4999):1360-3.
1991: Strobel S A; Dervan P B
Single-site enzymatic cleavage of yeast genomic DNA mediated by triple helix formation.
Nature 1991;350(6314):172-4.
1991: Maher L J; Wold B; Dervan P B
Oligonucleotide-directed DNA triple-helix formation: an approach to artificial repressors?
Antisense research and development 1991;1(3):277-81.
1990: Plum G E; Park Y W; Singleton S F; Dervan P B; Breslauer K J
Thermodynamic characterization of the stability and the melting behavior of a DNA triplex: a spectroscopic and calorimetric study.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(23):9436-40.
1990: Häner R; Dervan P B
Single-strand DNA triple-helix formation.
Biochemistry 1990;29(42):9761-5.
1990: Maher L J; Dervan P B; Wold B J
Kinetic analysis of oligodeoxyribonucleotide-directed triple-helix formation on DNA.
Biochemistry 1990;29(37):8820-6.
1990: Graham K S; Dervan P B
Structural motif of the DNA binding domain of gamma delta-resolvase characterized by affinity cleaving.
The Journal of biological chemistry 1990;265(27):16534-40.
1990: Mack D P; Sluka J P; Shin J A; Griffin J H; Simon M I; Dervan P B
Orientation of the putative recognition helix in the DNA-binding domain of Hin recombinase complexed with the hix site.
Biochemistry 1990;29(28):6561-7.
1990: Sluka J P; Horvath S J; Glasgow A C; Simon M I; Dervan P B
Importance of minor-groove contacts for recognition of DNA by the binding domain of Hin recombinase.
Biochemistry 1990;29(28):6551-61.
1990: Strobel S A; Dervan P B
Site-specific cleavage of a yeast chromosome by oligonucleotide-directed triple-helix formation.
Science (New York, N.Y.) 1990;249(4964):73-5.
1990: Oakley M G; Dervan P B
Structural motif of the GCN4 DNA binding domain characterized by affinity cleaving.
Science (New York, N.Y.) 1990;248(4957):847-50.
1989: Griffin L C; Dervan P B
Recognition of thymine adenine.base pairs by guanine in a pyrimidine triple helix motif.
Science (New York, N.Y.) 1989;245(4921):967-71.
1989: Maher L J; Wold B; Dervan P B
Inhibition of DNA binding proteins by oligonucleotide-directed triple helix formation.
Science (New York, N.Y.) 1989;245(4919):725-30.
1988: Iverson B L; Dervan P B
Nonenzymatic sequence-specific methyl transfer to single-stranded DNA.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(13):4615-9.
1987: Sluka J P; Horvath S J; Bruist M F; Simon M I; Dervan P B
Synthesis of a sequence-specific DNA-cleaving peptide.
Science (New York, N.Y.) 1987;238(4830):1129-32.
1987: Iverson B L; Dervan P B
Adenine specific DNA chemical sequencing reaction.
Nucleic acids research 1987;15(19):7823-30.
1987: Moser H E; Dervan P B
Sequence-specific cleavage of double helical DNA by triple helix formation.
Science (New York, N.Y.) 1987;238(4827):645-50.
1984: Schultz P G; Dervan P B
Distamycin and penta-N-methylpyrrolecarboxamide binding sites on native DNA. A comparison of methidiumpropyl-EDTA-Fe(II) footprinting and DNA affinity cleaving.
Journal of biomolecular structure & dynamics 1984;1(5):1133-47.

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