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Douglas DeSimone

Research Profile

Living Beings

Xenopus laevis

Chemicals & Drugs

Anatomy

Genes & Molecular Sequences

Amino Acid Sequences

Concepts & Ideas

Molecular Sequence Data

Physiology

Procedures

Cloning, Molecular

Co-author Network

Publications

TOP 3
Shuo Wei; Judith M White; Phoebe Williams; Guofeng Xu; Lance C Bridges; Robert M Grainger; Takuya Nakayama; Anoop Shah; Douglas W DeSimone
Roles of ADAM13-regulated Wnt activity in early Xenopus eye development.
Gregory F Weber; Maureen A Bjerke; Douglas W DeSimone
A mechanoresponsive cadherin-keratin complex directs polarized protrusive behavior and collective cell migration.
Guofeng Xu; Shuo Wei; Judith M White; Douglas W DeSimone
Identification and characterization of ADAM41, a novel ADAM metalloproteinase in Xenopus.

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All Publications

2012: Shuo Wei; Judith M White; Phoebe Williams; Guofeng Xu; Lance C Bridges; Robert M Grainger; Takuya Nakayama; Anoop Shah; Douglas W DeSimone
Roles of ADAM13-regulated Wnt activity in early Xenopus eye development.
Developmental biology 2012;363(1):147-54.
2012: Gregory F Weber; Maureen A Bjerke; Douglas W DeSimone
A mechanoresponsive cadherin-keratin complex directs polarized protrusive behavior and collective cell migration.
Developmental cell 2012;22(1):104-15.
2012: Guofeng Xu; Shuo Wei; Judith M White; Douglas W DeSimone
Identification and characterization of ADAM41, a novel ADAM metalloproteinase in Xenopus.
The International journal of developmental biology 2012;56(5):333-9.
2011: Gregory F Weber; Maureen A Bjerke; Douglas W DeSimone
Integrins and cadherins join forces to form adhesive networks.
Journal of cell science 2011;124(Pt 8):1183-93.
2010: Shuo Wei; Guofeng Xu; Lance C Bridges; Phoebe Williams; Judith M White; Douglas W DeSimone
ADAM13 induces cranial neural crest by cleaving class B Ephrins and regulating Wnt signaling.
Developmental cell 2010;19(2):345-52.
2010: Tania Rozario; Douglas W DeSimone
The extracellular matrix in development and morphogenesis: a dynamic view.
Developmental biology 2010;341(1):126-40.
2010: Shuo Wei; Charles A Whittaker; Guofeng Xu; Lance C Bridges; Anoop Shah; Judith M White; Douglas W DeSimone
Conservation and divergence of ADAM family proteins in the Xenopus genome.
BMC evolutionary biology 2010;10():211.
2009: Tania Rozario; Bette Dzamba; Gregory F Weber; Lance A Davidson; Douglas W DeSimone
The physical state of fibronectin matrix differentially regulates morphogenetic movements in vivo.
Developmental biology 2009;327(2):386-98.
2009: Bette Dzamba; Karoly R Jakab; Mungo Marsden; Martin A Schwartz; Douglas W DeSimone
Cadherin adhesion, tissue tension, and noncanonical Wnt signaling regulate fibronectin matrix organization.
Developmental cell 2009;16(3):421-32.
2008: Lance A Davidson; Bette Dzamba; Ray Keller; Douglas W DeSimone
Live imaging of cell protrusive activity, and extracellular matrix assembly and remodeling during morphogenesis in the frog, Xenopus laevis.
Developmental dynamics : an official publication of the American Association of Anatomists 2008;237(10):2684-92.
2008: Martin A Schwartz; Douglas W DeSimone
Cell adhesion receptors in mechanotransduction.
Current opinion in cell biology 2008;20(5):551-6.
2007: Bryan C Thorne; Alexander M Bailey; Douglas W DeSimone; Shayn M Peirce
Agent-based modeling of multicell morphogenic processes during development.
Birth defects research. Part C, Embryo today : reviews 2007;81(4):344-53.
2007: Scott H Robertson; Chris K Smith; Anna L Langhans; Sara E McLinden; Matthew A Oberhardt; Karoly R Jakab; Bette Dzamba; Douglas W DeSimone; Jason A Papin; Shayn M Peirce
Multiscale computational analysis of Xenopus laevis morphogenesis reveals key insights of systems-level behavior.
BMC systems biology 2007;1():46.
2007: Douglas W DeSimone; Bette Dzamba; Lance A Davidson
Using Xenopus embryos to investigate integrin function.
Methods in enzymology 2007;426():403-14.
2006: Lance A Davidson; Mungo Marsden; Ray Keller; Douglas W DeSimone
Integrin alpha5beta1 and fibronectin regulate polarized cell protrusions required for Xenopus convergence and extension.
Current biology : CB 2006;16(9):833-44.
2005: Douglas W DeSimone; Lance Davidson; Mungo Marsden; Dominique Alfandari
The Xenopus embryo as a model system for studies of cell migration.
Methods in molecular biology (Clifton, N.J.) 2005;294():235-45.
2004: Lance A Davidson; Ray Keller; Douglas W DeSimone
Assembly and remodeling of the fibrillar fibronectin extracellular matrix during gastrulation and neurulation in Xenopus laevis.
Developmental dynamics : an official publication of the American Association of Anatomists 2004;231(4):888-95.
2004: Diane Longo; Shayn M Peirce; Thomas C Skalak; Lance Davidson; Mungo Marsden; Bette Dzamba; Douglas W DeSimone
Multicellular computer simulation of morphogenesis: blastocoel roof thinning and matrix assembly in Xenopus laevis.
Developmental biology 2004;271(1):210-22.
2004: Lance A Davidson; Ray Keller; Douglas W DeSimone
Patterning and tissue movements in a novel explant preparation of the marginal zone of Xenopus laevis.
Gene expression patterns : GEP 2004;4(4):457-66.
2003: Dominique Alfandari; Hélène Cousin; Alban Gaultier; Benjamin G Hoffstrom; Douglas W DeSimone
Integrin alpha5beta1 supports the migration of Xenopus cranial neural crest on fibronectin.
Developmental biology 2003;260(2):449-64.
2003: Mungo Marsden; Douglas W DeSimone
Integrin-ECM interactions regulate cadherin-dependent cell adhesion and are required for convergent extension in Xenopus.
Current biology : CB 2003;13(14):1182-91.
2003: Jie Na; Mungo Marsden; Douglas W DeSimone
Differential regulation of cell adhesive functions by integrin alpha subunit cytoplasmic tails in vivo.
Journal of cell science 2003;116(Pt 11):2333-43.
2002: Katherine M Smith; Alban Gaultier; Hélène Cousin; Dominique Alfandari; Judith M White; Douglas W DeSimone
The cysteine-rich domain regulates ADAM protease function in vivo.
The Journal of cell biology 2002;159(5):893-902.
2002: Lance A Davidson; Benjamin G Hoffstrom; Ray Keller; Douglas W DeSimone
Mesendoderm extension and mantle closure in Xenopus laevis gastrulation: combined roles for integrin alpha(5)beta(1), fibronectin, and tissue geometry.
Developmental biology 2002;242(2):109-29.
2001: Mungo Marsden; Douglas W DeSimone
Regulation of cell polarity, radial intercalation and epiboly in Xenopus: novel roles for integrin and fibronectin.
Development (Cambridge, England) 2001;128(18):3635-47.
2001: Dominique Alfandari; Hélène Cousin; Alban Gaultier; K Smith; Judith M White; Thierry Darribère; Douglas W DeSimone
Xenopus ADAM 13 is a metalloprotease required for cranial neural crest-cell migration.
Current biology : CB 2001;11(12):918-30.
2000: M W Cohen; Benjamin G Hoffstrom; Douglas W DeSimone
Active zones on motor nerve terminals contain alpha 3beta 1 integrin.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2000;20(13):4912-21.
1998: CA Whittaker; Douglas W DeSimone
Molecular cloning and developmental expression of the Xenopus homolog of integrin alpha 4.
Annals of the New York Academy of Sciences 1998;857():56-73.
1998: L A Urry; CA Whittaker; M Duquette; J Lawler; Douglas W DeSimone
Thrombospondins in early Xenopus embryos: dynamic patterns of expression suggest diverse roles in nervous system, notochord, and muscle development.
Developmental dynamics : an official publication of the American Association of Anatomists 1998;211(4):390-407.
1997: F Meng; CA Whittaker; David G. Ransom; Douglas W DeSimone
Cloning and characterization of cDNAs encoding the integrin alpha2 and alpha3 subunits from Xenopus laevis.
Mechanisms of development 1997;67(2):141-55.
1997: Dominique Alfandari; T G Wolfsberg; Judith M White; Douglas W DeSimone
ADAM 13: a novel ADAM expressed in somitic mesoderm and neural crest cells during Xenopus laevis development.
Developmental biology 1997;182(2):314-30.
1996: Joe W Ramos; C A Whittaker; Douglas W DeSimone
Integrin-dependent adhesive activity is spatially controlled by inductive signals at gastrulation.
Development (Cambridge, England) 1996;122(9):2873-83.
1996: T E Lallier; C A Whittaker; Douglas W DeSimone
Integrin alpha 6 expression is required for early nervous system development in Xenopus laevis.
Development (Cambridge, England) 1996;122(8):2539-54.
1996: Joe W Ramos; Douglas W DeSimone
Xenopus embryonic cell adhesion to fibronectin: position-specific activation of RGD/synergy site-dependent migratory behavior at gastrulation.
The Journal of cell biology 1996;134(1):227-40.
1996: Dominique Alfandari; Joe W Ramos; L Clavilier; Douglas W DeSimone; T Darribère
The RGD-dependent and the Hep II binding domains of fibronectin govern the adhesive behaviors of amphibian embryonic cells.
Mechanisms of development 1996;56(1-2):83-92.
1995: M D Hens; Douglas W DeSimone
Molecular analysis and developmental expression of the focal adhesion kinase pp125FAK in Xenopus laevis.
Developmental biology 1995;170(2):274-88.
1995: Dominique Alfandari; C A Whittaker; Douglas W DeSimone; T Darribère
Integrin alpha v subunit is expressed on mesodermal cell surfaces during amphibian gastrulation.
Developmental biology 1995;170(2):249-61.
1995: Thomas O Joos; C A Whittaker; F Meng; Douglas W DeSimone; V Gnau; P Hausen
Integrin alpha 5 during early development of Xenopus laevis.
Mechanisms of development 1995;50(2-3):187-99.
1994: Douglas W DeSimone
Adhesion and matrix in vertebrate development.
Current opinion in cell biology 1994;6(5):747-51.
1993: David G. Ransom; M D Hens; Douglas W DeSimone
Integrin expression in early amphibian embryos: cDNA cloning and characterization of Xenopus beta 1, beta 2, beta 3, and beta 6 subunits.
Developmental biology 1993;160(1):265-75.
1993: L Clavilier; J F Riou; De-Li Shi; Douglas W DeSimone; Jean-Claude Boucaut
Amphibian Pleurodeles waltl fibronectin: cDNA cloning and developmental expression of spliced variants.
Cell adhesion and communication 1993;1(1):83-91.
1993: C A Whittaker; Douglas W DeSimone
Integrin alpha subunit mRNAs are differentially expressed in early Xenopus embryos.
Development (Cambridge, England) 1993;117(4):1239-49.
1993: J Lawler; M Duquette; C A Whittaker; J C Adams; K McHenry; Douglas W DeSimone
Identification and characterization of thrombospondin-4, a new member of the thrombospondin gene family.
The Journal of cell biology 1993;120(4):1059-67.
1992: De-Li Shi; Jean-Jacques Feige; J F Riou; Douglas W DeSimone; Jean-Claude Boucaut
Differential expression and regulation of two distinct fibroblast growth factor receptors during early development of the urodele amphibian Pleurodeles waltl.
Development (Cambridge, England) 1992;116(1):261-73.
1992: Douglas W DeSimone; P A Norton; R O Hynes
Identification and characterization of alternatively spliced fibronectin mRNAs expressed in early Xenopus embryos.
Developmental biology 1992;149(2):357-69.
1992: K E Johnson; Jean-Claude Boucaut; Douglas W DeSimone
Role of the extracellular matrix in amphibian gastrulation.
Current topics in developmental biology 1992;27():91-127.
1991: Douglas W DeSimone; K E Johnson
The Xenopus embryo as a model system for the study of cell-extracellular matrix interactions.
Methods in cell biology 1991;36():527-39.