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Gary Desir

Research Profile

Chemicals & Drugs

Living Beings

Anatomy

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Molecular Sequence Data

Physiology

Ion Channel Gating

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Amino Acid Sequences

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Cloning, Molecular

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Publications

TOP 3
Aldo J Peixoto; M Orias; Gary V Desir
Does kidney disease cause hypertension?
H Thomas Lee; Lieqi Tang; Peili Wang; Sara Baroni; Vivette D D'Agati; Joo Yun Kim; Mihwa Kim; Gary V Desir
Renalase protects against ischemic AKI.
Gary V Desir; Ling Wang; Aldo J Peixoto
Human renalase: a review of its biology, function, and implications for hypertension.

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All Publications

2013: Aldo J Peixoto; M Orias; Gary V Desir
Does kidney disease cause hypertension?
Current hypertension reports 2013;15(2):89-94.
2013: H Thomas Lee; Lieqi Tang; Peili Wang; Sara Baroni; Vivette D D'Agati; Joo Yun Kim; Mihwa Kim; Gary V Desir
Renalase protects against ischemic AKI.
Journal of the American Society of Nephrology : JASN 2013;24(3):445-55.
2012: Gary V Desir; Ling Wang; Aldo J Peixoto
Human renalase: a review of its biology, function, and implications for hypertension.
Journal of the American Society of Hypertension : JASH 2012;6(6):417-26.
2012: Gary V Desir; Guoyong Li; Manuel Pestana; Janete Quelhas-Santos; Benedita Sampaio-Maia; Lieqi Tang; Peili Wang; Heino Velazquez
Renalase lowers ambulatory blood pressure by metabolizing circulating adrenaline.
Journal of the American Heart Association 2012;1(4):e002634.
2011: Edward J Weinman; Rajatsubhra Biswas; Deborah Steplock; Peili Wang; Yuen-Sum Lau; Gary V Desir; Shirish Shenolikar
Increased renal dopamine and acute renal adaptation to a high-phosphate diet.
American journal of physiology. Renal physiology 2011;300(5):F1123-9.
2011: Yanling Wu; Jianchao Xu; Heino Velazquez; Peili Wang; Guoyong Li; Dinggang Liu; Benedita Sampaio-Maia; Janete Quelhas-Santos; Kerry Russell; Raymond Russell; Richard A Flavell; Manuel Pestana; Frank Giordano; Gary V Desir
Renalase deficiency aggravates ischemic myocardial damage.
Kidney international 2011;79(8):853-60.
2011: Gary V Desir
Role of renalase in the regulation of blood pressure and the renal dopamine system.
Current opinion in nephrology and hypertension 2011;20(1):31-6.
2010: Robert F Reilly; Aldo J Peixoto; Gary V Desir
The evidence-based use of thiazide diuretics in hypertension and nephrolithiasis.
Clinical journal of the American Society of Nephrology : CJASN 2010;5(10):1893-903.
2010: Ramin Farzaneh-Far; Gary V Desir; Beeya Na; Nelson B Schiller; Mary A Whooley
A functional polymorphism in renalase (Glu37Asp) is associated with cardiac hypertrophy, dysfunction, and ischemia: data from the heart and soul study.
PloS one 2010;5(10):e13496.
2009: Felix Knauf; Gary V Desir; Mark A Perazella
A case of extreme hemodynamic lability and hypocalcemia.
The American journal of the medical sciences 2009;338(3):241-4.
2009: Gary V Desir
Regulation of blood pressure and cardiovascular function by renalase.
Kidney international 2009;76(4):366-70.
2008: Guoyong Li; Jianchao Xu; Peili Wang; Heino Velazquez; Yanyan Li; Yanling Wu; Gary V Desir
Catecholamines regulate the activity, secretion, and synthesis of renalase.
Circulation 2008;117(10):1277-82.
2008: Gary V Desir
Renalase deficiency in chronic kidney disease, and its contribution to hypertension and cardiovascular disease.
Current opinion in nephrology and hypertension 2008;17(2):181-5.
2007: Yanyan Li; Peili Wang; Jianchao Xu; Fred S Gorelick; Hanae Yamazaki; Norma W Andrews; Gary V Desir
Regulation of insulin secretion and GLUT4 trafficking by the calcium sensor synaptotagmin VII.
Biochemical and biophysical research communications 2007;362(3):658-64.
2007: Jianchao Xu; Gary V Desir
Renalase, a new renal hormone: its role in health and disease.
Current opinion in nephrology and hypertension 2007;16(4):373-8.
2007: Gary V Desir
Renalase is a novel renal hormone that regulates cardiovascular function.
Journal of the American Society of Hypertension : JASH 2007;1(2):99-103.
2006: Yanyan Li; Peili Wang; Jianchao Xu; Gary V Desir
Voltage-gated potassium channel Kv1.3 regulates GLUT4 trafficking to the plasma membrane via a Ca2+-dependent mechanism.
American journal of physiology. Cell physiology 2006;290(2):C345-51.
2005: Gary V Desir
Kv1.3 potassium channel blockade as an approach to insulin resistance.
Expert opinion on therapeutic targets 2005;9(3):571-9.
2005: Jianchao Xu; Guoyong Li; Peili Wang; Heino Velazquez; Xiaoqiang Yao; Yanyan Li; Yanling Wu; Aldo Peixoto; Susan Crowley; Gary V Desir
Renalase is a novel, soluble monoamine oxidase that regulates cardiac function and blood pressure.
The Journal of clinical investigation 2005;115(5):1275-80.
2004: Jianchao Xu; Peili Wang; Yanyan Li; Guoyong Li; Leonard K Kaczmarek; Yanling Wu; Pandelakis Koni; Richard A Flavell; Gary V Desir
The voltage-gated potassium channel Kv1.3 regulates peripheral insulin sensitivity.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(9):3112-7.
2003: Jianchao Xu; Pandelakis Koni; Peili Wang; Guoyong Li; Leonard Kaczmarek; Yanling Wu; Yanyan Li; Richard A Flavell; Gary V Desir
The voltage-gated potassium channel Kv1.3 regulates energy homeostasis and body weight.
Human molecular genetics 2003;12(5):551-9.
2002: Xiaoqiang Yao; Shulan Tian; Ho-Yu Chan; Daniel Biemesderfer; Gary V Desir
Expression of KCNA10, a voltage-gated K channel, in glomerular endothelium and at the apical membrane of the renal proximal tubule.
Journal of the American Society of Nephrology : JASN 2002;13(12):2831-9.
2002: Alan S Segal; John P Hayslett; Gary V Desir
On the natriuretic effect of verapamil: inhibition of ENaC and transepithelial sodium transport.
American journal of physiology. Renal physiology 2002;283(4):F765-70.
2002: Shulan Tian; Weimin Liu; Yanling Wu; Hamid Rafi; Alan S Segal; Gary V Desir
Regulation of the voltage-gated K+ channel KCNA10 by KCNA4B, a novel beta-subunit.
American journal of physiology. Renal physiology 2002;283(1):F142-9.
2001: Heino Velázquez; Teresa Silva; E Andújar; Gary V Desir; David H Ellison; R Greger
The distal convoluted tubule of rabbit kidney does not express a functional sodium channel.
American journal of physiology. Renal physiology 2001;280(3):F530-9.
2000: R Lang; G Lee; Weimin Liu; Shulan Tian; Hamid Rafi; M Orias; Alan S Segal; Gary V Desir
KCNA10: a novel ion channel functionally related to both voltage-gated potassium and CNG cation channels.
American journal of physiology. Renal physiology 2000;278(6):F1013-21.
2000: xiaoqiang yao; Weimin Liu; Shulan Tian; Hamid Rafi; Alan S Segal; Gary V Desir
Close association of the N terminus of Kv1.3 with the pore region.
The Journal of biological chemistry 2000;275(15):10859-63.
1999: S Kunchaparty; M Palcso; J Berkman; Heino Velázquez; Gary V Desir; P Bernstein; Robert F Reilly; David H Ellison
Defective processing and expression of thiazide-sensitive Na-Cl cotransporter as a cause of Gitelman's syndrome.
The American journal of physiology 1999;277(4 Pt 2):F643-9.
1999: Alan S Segal; X Yao; Gary V Desir
The T0 domain of rabbit KV1.3 regulates steady state channel protein level.
Biochemical and biophysical research communications 1999;254(1):54-64.
1998: X Yao; Y Huang; H Y Kwan; P Chan; A S Segal; Gary V Desir
Characterization of a regulatory region in the N-terminus of rabbit kv1.3.
Biochemical and biophysical research communications 1998;249(2):492-8.
1998: Heino Velázquez; Anikó Náray-Fejes-Tóth; Teresa Silva; E Andújar; Robert F Reilly; Gary V Desir; David H Ellison
Rabbit distal convoluted tubule coexpresses NaCl cotransporter and 11 beta-hydroxysteroid dehydrogenase II mRNA.
Kidney international 1998;54(2):464-72.
1997: M Orias; Heino Velázquez; F Tung; G Lee; Gary V Desir
Cloning and localization of a double-pore K channel, KCNK1: exclusive expression in distal nephron segments.
The American journal of physiology 1997;273(4 Pt 2):F663-6.
1997: M Orias; Patricia Bray-Ward; Mark E Curran; Mark T Keating; Gary V Desir
Genomic localization of the human gene for KCNA10, a cGMP-activated K channel.
Genomics 1997;42(1):33-7.
1996: X Yao; Y Liu; F Tung; Gary V Desir
Genomic structure and regulation of Kcn1, a cGMP-gated potassium channel.
The American journal of physiology 1996;271(1 Pt 2):F37-41.
1996: X Yao; A Y Chang; Emile L Boulpaep; Alan S Segal; Gary V Desir
Molecular cloning of a glibenclamide-sensitive, voltage-gated potassium channel expressed in rabbit kidney.
The Journal of clinical investigation 1996;97(11):2525-33.
1995: X Yao; Alan S Segal; Fang Liang; X Zhang; CM McNicholas; D Engel; Emile L Boulpaep; Gary V Desir
Primary structure and functional expression of a cGMP-gated potassium channel.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(25):11711-5.
1995: Gary V Desir
Molecular characterization of voltage and cyclic nucleotide-gated potassium channels in kidney.
Kidney international 1995;48(4):1031-5.
1995: Gary V Desir
The structure, regulation and pathophysiology of potassium channels.
Current opinion in nephrology and hypertension 1995;4(5):402-5.
1993: David H Ellison; D Biemesderfer; J Morrisey; J Lauring; Gary V Desir
Immunocytochemical characterization of the high-affinity thiazide diuretic receptor in rabbit renal cortex.
The American journal of physiology 1993;264(1 Pt 2):F141-8.
1993: Gary V Desir; Heino Velázquez
Identification of a novel K-channel gene (KC22) that is highly expressed in distal tubule of rabbit kidney.
The American journal of physiology 1993;264(1 Pt 2):F128-33.
1992: Gary V Desir
Molecular physiology of renal potassium channels.
Seminars in nephrology 1992;12(6):531-40.
1992: A Zweifach; Gary V Desir; Peter S Aronson; Gerhard Giebisch
Inhibition of Ca-activated K+ channels from renal microvillus membrane vesicles by amiloride analogs.
The Journal of membrane biology 1992;128(2):115-22.
1992: Gary V Desir; H A Hamlin; E Puente; Robert F Reilly; Friedhelm Hildebrandt; Peter Igarashi
Isolation of putative voltage-gated epithelial K-channel isoforms from rabbit kidney and LLC-PK1 cells.
The American journal of physiology 1992;262(1 Pt 2):F151-7.
1991: David H Ellison; J Morrisey; Gary V Desir
Solubilization and partial purification of the thiazide diuretic receptor from rabbit renal cortex.
Biochimica et biophysica acta 1991;1069(2):241-9.
1991: Gary V Desir
Reconstitution and partial purification of an amiloride-sensitive, cation channel from rabbit kidney.
Biochimica et biophysica acta 1991;1067(1):38-42.
1991: A Zweifach; Gary V Desir; Peter S Aronson; Gerhard Giebisch
A Ca-activated K channel from rabbit renal brush-border membrane vesicles in planar lipid bilayers.
The American journal of physiology 1991;261(1 Pt 2):F187-96.
1991: Gary V Desir; E J Cragoe; Peter S Aronson
High affinity binding of amiloride analogs at an internal site in renal microvillus membrane vesicles.
The Journal of biological chemistry 1991;266(4):2267-71.