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Sevilla Detera-Wadleigh

Research Profile

Disorders

Concepts & Ideas

Physiology

Anatomy

Chromosomes, Human, Pair 18

Procedures

Genes & Molecular Sequences

Chemicals & Drugs

Organizations

National Institute of Mental Health (U.S.)

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Publications

TOP 3
A Gupta; N Hunter; X-y Jiang; Francis McMajon; V Nagarajan; Thomas G. Schulze; Nirmala Akula; Winston Corona; Sevilla D Detera-Wadleigh
Interaction networks of lithium and valproate molecular targets reveal a striking enrichment of apoptosis functional clusters and neurotrophin signaling.
Sevilla D Detera-Wadleigh; Nirmala Akula
A systems approach to the biology of mood disorders through network analysis of candidate genes.
Francis McMajon; Nirmala Akula; Thomas G. Schulze; Pierandrea Muglia; Federica Tozzi; Sevilla D Detera-Wadleigh; C J M Steele; René Breuer; Jana Strohmaier; Jens R Wendland; Manuel Mattheisen; Thomas W Mühleisen; Wolfgang Maier; Markus M Nöthen; Sven Cichon; Anne Farmer; John B Vincent; Florian Holsboer; Martin Preisig; Marcella Rietschel
Meta-analysis of genome-wide association data identifies a risk locus for major mood disorders on 3p21.1.

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All Publications

2012: A Gupta; N Hunter; X-y Jiang; Francis McMajon; V Nagarajan; Thomas G. Schulze; Nirmala Akula; Winston Corona; Sevilla D Detera-Wadleigh
Interaction networks of lithium and valproate molecular targets reveal a striking enrichment of apoptosis functional clusters and neurotrophin signaling.
The pharmacogenomics journal 2012;12(4):328-41.
2011: Sevilla D Detera-Wadleigh; Nirmala Akula
A systems approach to the biology of mood disorders through network analysis of candidate genes.
Pharmacopsychiatry 2011;44 Suppl 1():S35-42.
2010: Francis McMajon; Nirmala Akula; Thomas G. Schulze; Pierandrea Muglia; Federica Tozzi; Sevilla D Detera-Wadleigh; C J M Steele; René Breuer; Jana Strohmaier; Jens R Wendland; Manuel Mattheisen; Thomas W Mühleisen; Wolfgang Maier; Markus M Nöthen; Sven Cichon; Anne Farmer; John B Vincent; Florian Holsboer; Martin Preisig; Marcella Rietschel
Meta-analysis of genome-wide association data identifies a risk locus for major mood disorders on 3p21.1.
Nature genetics 2010;42(2):128-31.
2009: Joanne M A Meerabux; Hisako Ohba; Yoshimi Iwayama; Motoko Maekawa; Sevilla D Detera-Wadleigh; Lynn E DeLisi; Takeo Yoshikawa
Analysis of a t(18;21)(p11.1;p11.1) translocation in a family with schizophrenia.
Journal of human genetics 2009;54(7):386-91.
2009: Thomas G. Schulze; Sevilla D Detera-Wadleigh; Nirmala Akula; A Gupta; L Kassem; Jo Steele; J Pearl; J Strohmaier; R Breuer; M Schwarz; Peter Propping; Markus M Nöthen; Sven Cichon; Johannes Schumacher; Marcella Rietschel; Francis McMajon
Two variants in Ankyrin 3 (ANK3) are independent genetic risk factors for bipolar disorder.
Molecular psychiatry 2009;14(5):487-91.
2008: Jens R Wendland; Theresa B DeGuzman; Francis McMajon; Gary Rudnick; Sevilla D Detera-Wadleigh; Dennis L Murphy
SERT Ileu425Val in autism, Asperger syndrome and obsessive-compulsive disorder.
Psychiatric genetics 2008;18(1):31-9.
2008: Kenji Amano; Kazuo Yamada; Yoshimi Iwayama; Sevilla D Detera-Wadleigh; Eiji Hattori; Tomoko Toyota; Katsushi Tokunaga; Takeo Yoshikawa; Kazuhiro Yamakawa
Association study between the Down syndrome cell adhesion molecule (DSCAM) gene and bipolar disorder.
Psychiatric genetics 2008;18(1):1-10.
2008: A E Baum; Nirmala Akula; M Cabanero; I Cardona; Winston Corona; B Klemens; Thomas G. Schulze; Sven Cichon; Marcella Rietschel; Markus M Nöthen; Alexander Georgi; Johannes Schumacher; M Schwarz; Rami Abou Jamra; Susanne Höfels; Peter Propping; Jaya M Satagopan; Sevilla D Detera-Wadleigh; John Hardy; Francis McMajon
A genome-wide association study implicates diacylglycerol kinase eta (DGKH) and several other genes in the etiology of bipolar disorder.
Molecular psychiatry 2008;13(2):197-207.
2008: James B Potash; Silvia Buervenich; Nancy J Cox; Peter P Zandi; Nirmala Akula; Jo Steele; Jennifer A Rathe; Dimitrios Avramopoulos; Sevilla D Detera-Wadleigh; Elliot S Gershon; J. Raymond DePaulo; Andrew P Feinberg; Francis McMajon
Gene-based SNP mapping of a psychotic bipolar affective disorder linkage region on 22q12.3: association with HMG2L1 and TOM1.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2008;147B(1):59-67.
2007: Sevilla D Detera-Wadleigh; Chun-yu Liu; Manjula Maheshwari; Imer Cardona; Winston Corona; Nirmala Akula; C J M Steele; Judith A Badner; Mukta Kundu; Layla Kassem; James B Potash; Richard Gibbs; Elliot S Gershon; Francis McMajon
Sequence variation in DOCK9 and heterogeneity in bipolar disorder.
Psychiatric genetics 2007;17(5):274-86.
2007: Tetsuo Ohnishi; Kazuo Yamada; Hisako Ohba; Yoshimi Iwayama; Tomoko Toyota; Eiji Hattori; Toshiya Inada; Hiroshi Kunugi; Masahiko Tatsumi; Norio Ozaki; Nakao Iwata; Kaoru Sakamoto; Yoshimi Iijima; Yasuhide Iwata; Kenji J Tsuchiya; Genichi Sugihara; Shinichiro Nanko; Noriko Osumi; Sevilla D Detera-Wadleigh; Tadafumi Kato; Takeo Yoshikawa
A promoter haplotype of the inositol monophosphatase 2 gene (IMPA2) at 18p11.2 confers a possible risk for bipolar disorder by enhancing transcription.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2007;32(8):1727-37.
2007: Grados Marco; Jack Samuels; Yin Yao Shugart; Virginia L Willour; Y Wang; Bernadette Cullen; OSCAR BIENVENU; Rudolf Hoehn-Saric; David Valle; Kung-Yee Liang; Mark A Riddle; J R Wendland; Dennis L Murphy; Gerald Nestadt; Sevilla D Detera-Wadleigh
Rare plus common SERT variants in obsessive-compulsive disorder.
Molecular psychiatry 2007;12(5):422-3.
2007: Tetsushi Sadakata; Miwa Washida; Yoshimi Iwayama; Satoshi Shoji; Yumi Sato; Takeshi Ohkura; Ritsuko Katoh-Semba; Mizuho Nakajima; Yukiko Sekine; Mika Tanaka; Kazuhiko Nakamura; Yasuhide Iwata; Kenji J Tsuchiya; Norio Mori; Sevilla D Detera-Wadleigh; Hironobu Ichikawa; Shigeyoshi Itohara; Takeo Yoshikawa; Teiichi Furuichi
Autistic-like phenotypes in Cadps2-knockout mice and aberrant CADPS2 splicing in autistic patients.
The Journal of clinical investigation 2007;117(4):931-43.
2007: Stéphanie Le Hellard; Andrew J Lee; Sarah Underwood; Pippa A Thomson; stewart morris; Helen S Torrance; Susan M Anderson; Richard R Adams; Pau Navarro; Andrea Christoforou; Lorna M Houlihan; Sevilla D Detera-Wadleigh; Michael J Owen; Philip Asherson; Walter J Muir; D H R Blackwood; Naomi R Wray; David J Porteous; Kathryn L Evans
Haplotype analysis and a novel allele-sharing method refines a chromosome 4p locus linked to bipolar affective disorder.
Biological psychiatry 2007;61(6):797-805.
2007: Victor Lopez; Sevilla D Detera-Wadleigh; Imer Cardona; Layla Kassem; Francis McMajon
Nested association between genetic variation in tryptophan hydroxylase II, bipolar affective disorder, and suicide attempts.
Biological psychiatry 2007;61(2):181-6.
2006: Sevilla D Detera-Wadleigh; Francis McMajon
G72/G30 in schizophrenia and bipolar disorder: review and meta-analysis.
Biological psychiatry 2006;60(2):106-14.
2006: Kazuo Yamada; Eiji Hattori; Yoshimi Iwayama; Tetsuo Ohnishi; Hisako Ohba; Tomoko Toyota; Hitomi Takao; Yoshio Minabe; Noriaki Nakatani; Teruhiko Higuchi; Sevilla D Detera-Wadleigh; Takeo Yoshikawa
Distinguishable haplotype blocks in the HTR3A and HTR3B region in the Japanese reveal evidence of association of HTR3B with female major depression.
Biological psychiatry 2006;60(2):192-201.
2006: Bora E Baysal; Joan E Willett-Brozick; Silviu-Alin Bacanu; Sevilla D Detera-Wadleigh; Vishwajit L Nimgaonkar
Common variations in ALG9 are not associated with bipolar I disorder: a family-based study.
Behavioral and brain functions : BBF 2006;2():25.
2005: Dilberto O Ferraren; Chunyu Liu; Judith A Badner; Winston Corona; Azadeh Rezvani; Virginia D Monje; Elliot S Gershon; Tom Bonner; Sevilla D Detera-Wadleigh
Linkage disequilibrium analysis in the LOC93081-KDELC1-BIVM region on 13q in bipolar disorder.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2005;133B(1):12-7.
2004: Sevilla D Detera-Wadleigh; Francis McMajon
Genetic association studies in mood disorders: issues and promise.
International review of psychiatry (Abingdon, England) 2004;16(4):301-10.
2004: Thomas G. Schulze; Silvia Buervenich; Judith A Badner; C J M Steele; Sevilla D Detera-Wadleigh; Danielle Dick; Tatiana Foroud; Nancy J Cox; Dean F MacKinnon; James B Potash; Wade H Berrettini; William Byerley; William Coryell; J. Raymond DePaulo; Elliot S Gershon; John R Kelsoe; Melvin G McInnis; Dennis L Murphy; Theodore Reich; William A Scheftner; John I Nurnberger; Francis McMajon
Loci on chromosomes 6q and 6p interact to increase susceptibility to bipolar affective disorder in the national institute of mental health genetics initiative pedigrees.
Biological psychiatry 2004;56(1):18-23.
2004: Yasue Horiuchi; Junko Nakayama; Hiroki Ishiguro; Tsuyuka Ohtsuki; Sevilla D Detera-Wadleigh; Tomoko Toyota; Kazuo Yamada; Masahiro Nankai; Haruo Shibuya; Takeo Yoshikawa; Tadao Arinami
Possible association between a haplotype of the GABA-A receptor alpha 1 subunit gene (GABRA1) and mood disorders.
Biological psychiatry 2004;55(1):40-5.
2004: Yu-Sheng Chen; Nirmala Akula; Sevilla D Detera-Wadleigh; Thomas G. Schulze; J Thomas; James B Potash; J. Raymond DePaulo; Melvin G McInnis; Nancy J Cox; Francis McMajon
Findings in an independent sample support an association between bipolar affective disorder and the G72/G30 locus on chromosome 13q33.
Molecular psychiatry 2004;9(1):87-92; image 5.
2003: Dennis L Murphy; George R. Uhl; Andrew Holmes; Renee F Ren-Patterson; F Scott Hall; I Sora; Sevilla D Detera-Wadleigh; Klaus-Peter Lesch
Experimental gene interaction studies with SERT mutant mice as models for human polygenic and epistatic traits and disorders.
Genes, brain, and behavior 2003;2(6):350-64.
2003: Melvin G McInnis; Danielle M Dick; Virginia L Willour; Dimitrios Avramopoulos; Dean F MacKinnon; Sylvia G Simpson; James B Potash; Howard J Edenberg; Elizabeth S Bowman; Francis McMajon; Carrie Smiley; Jennifer Chellis; Yuqing Huo; Tyra Diggs; Eric T Meyer; Marvin Miller; Amy T Matteini; N Leela Rau; J. Raymond DePaulo; Elliot S Gershon; Judith A Badner; John P Rice; Alison Goate; Sevilla D Detera-Wadleigh; John I Nurnberger; Theodore Reich; Peter P Zandi; Tatiana Foroud
Genome-wide scan and conditional analysis in bipolar disorder: evidence for genomic interaction in the National Institute of Mental Health genetics initiative bipolar pedigrees.
Biological psychiatry 2003;54(11):1265-73.
2003: Masanari Itokawa; Kazuo Yamada; Yoshimi Iwayama-Shigeno; Yuichi Ishitsuka; Sevilla D Detera-Wadleigh; Takeo Yoshikawa
Genetic analysis of a functional GRIN2A promoter (GT)n repeat in bipolar disorder pedigrees in humans.
Neuroscience letters 2003;345(1):53-6.
2003: Eiji Hattori; Chunyu Liu; Judith A Badner; Tom Bonner; Susan L Christian; Manjula Maheshwari; Sevilla D Detera-Wadleigh; Richard A Gibbs; Elliot S Gershon
Polymorphisms at the G72/G30 gene locus, on 13q33, are associated with bipolar disorder in two independent pedigree series.
American journal of human genetics 2003;72(5):1131-40.
2003: Yoshimi Iwayama-Shigeno; Kazuo Yamada; Tomoko Toyota; Hiromitsu Shimizu; Eiji Hattori; Kiyoshi Yoshitsugu; Tetsuya Fujisawa; Yukako Yoshida; Toshio Kobayashi; Michio Toru; Akeo Kurumaji; Sevilla D Detera-Wadleigh; Takeo Yoshikawa
Distribution of haplotypes derived from three common variants of the NR4A2 gene in Japanese patients with schizophrenia.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2003;118B(1):20-4.
2003: Tomoko Toyota; Kazuo Yamada; Sevilla D Detera-Wadleigh; Takeo Yoshikawa
Analysis of a cluster of polymorphisms in AKT1 gene in bipolar pedigrees: a family-based association study.
Neuroscience letters 2003;339(1):5-8.
2002: Sander Rensen; Victor L J L Thijssen; Carlie J M de Vries; Pieter A Doevendans; Sevilla D Detera-Wadleigh; Guillaume J J M van Eys
Expression of the smoothelin gene is mediated by alternative promoters.
Cardiovascular research 2002;55(4):850-63.
2002: Bora E Baysal; Joan E Willett-Brozick; Judith A Badner; Winston Corona; Robert E Ferrell; Vishwajit L Nimgaonkar; Sevilla D Detera-Wadleigh
A mannosyltransferase gene at 11q23 is disrupted by a translocation breakpoint that co-segregates with bipolar affective disorder in a small family.
Neurogenetics 2002;4(1):43-53.
2002: T Ohtsuki; Hiroki Ishiguro; Sevilla D Detera-Wadleigh; Tomoko Toyota; H Shimizu; Kazuo Yamada; Kiyoshi Yoshitsugu; Eiji Hattori; Takeo Yoshikawa; Tadao Arinami
Association between serotonin 4 receptor gene polymorphisms and bipolar disorder in Japanese case-control samples and the NIMH Genetics Initiative Bipolar Pedigrees.
Molecular psychiatry 2002;7(9):954-61.
2002: G D Reyes; LE Esterling; Winston Corona; D Ferraren; DY Rollins; M Padigaru; Takeo Yoshikawa; V D Monje; Sevilla D Detera-Wadleigh
Map of candidate genes and STSs on 18p11.2, a bipolar disorder and schizophrenia susceptibility region.
Molecular psychiatry 2002;7(4):337-9.
2001: Chunyu Liu; Judith A Badner; Susan L Christian; JJ Guroff; Sevilla D Detera-Wadleigh; Elliot S Gershon
Fine mapping supports previous linkage evidence for a bipolar disorder susceptibility locus on 13q32.
American journal of medical genetics 2001;105(4):375-80.
2001: Sevilla D Detera-Wadleigh
Lithium-related genetics of bipolar disorder.
Annals of medicine 2001;33(4):272-85.
2001: Takeo Yoshikawa; M Kikuchi; K Saito; A Watanabe; Kazuo Yamada; Haruo Shibuya; Masahiro Nankai; Akeo Kurumaji; Eiji Hattori; Hiroki Ishiguro; H Shimizu; Y Okubo; Michio Toru; Sevilla D Detera-Wadleigh
Evidence for association of the myo-inositol monophosphatase 2 (IMPA2) gene with schizophrenia in Japanese samples.
Molecular psychiatry 2001;6(2):202-10.
2000: Tomoko Toyota; A Watanabe; Haruo Shibuya; Masahiro Nankai; Eiji Hattori; Kazuo Yamada; Akeo Kurumaji; JD Karkera; Sevilla D Detera-Wadleigh; Takeo Yoshikawa
Association study on the DUSP6 gene, an affective disorder candidate gene on 12q23, performed by using fluorescence resonance energy transfer-based melting curve analysis on the LightCycler.
Molecular psychiatry 2000;5(5):461, 489-94.
2000: JD Karkera; S Ayache; R J Ransome; M A Jackson; A F Elsayem; R Sridhar; Sevilla D Detera-Wadleigh; Robert Wadleigh
Refinement of regions with allelic loss on chromosome 18p11.2 and 18q12.2 in esophageal squamous cell carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(9):3565-9.
2000: Takeo Yoshikawa; M Padigaru; JD Karkera; M Sharma; Wade H Berrettini; LE Esterling; Sevilla D Detera-Wadleigh
Genomic structure and novel variants of myo-inositol monophosphatase 2 (IMPA2).
Molecular psychiatry 2000;5(2):165-71.
2000: Tatiana Foroud; Peter Castelluccio; Daniel L Koller; Howard J Edenberg; Marvin Miller; Elizabeth Bowman; N Leela Rau; Carrie Smiley; John P Rice; Alison Goate; C Armstrong; Laura J Bierut; Theodore Reich; Sevilla D Detera-Wadleigh; LR Goldin; Judith A Badner; JJ Guroff; Elliot S Gershon; Francis McMajon; Sylvia G Simpson; Dean F MacKinnon; Melvin G McInnis; O Colin Stine; J. Raymond DePaulo; MC Blehar; John I Nurnberger
Suggestive evidence of a locus on chromosome 10p using the NIMH genetics initiative bipolar affective disorder pedigrees.
American journal of medical genetics 2000;96(1):18-23.
1999: Raji Grewal; JD Karkera; R K Grewal; Sevilla D Detera-Wadleigh
Mutation analysis of oculopharyngeal muscular dystrophy in Hispanic American families.
Archives of neurology 1999;56(11):1378-81.
1999: Allen R Rhoads; JD Karkera; Sevilla D Detera-Wadleigh
Radiation hybrid mapping of genes in the lithium-sensitive wnt signaling pathway.
Molecular psychiatry 1999;4(5):437-42.
1999: Sevilla D Detera-Wadleigh
Chromosomes 12 and 16 workshop.
American journal of medical genetics 1999;88(3):255-9.
1999: Svetlana D Pack; JD Karkera; Zhengping Zhuang; Evgenia Pak; K V Balan; P Hwu; WS Park; T Pham; David O Ault; M Glaser; Lance A Liotta; Sevilla D Detera-Wadleigh; Robert Wadleigh
Molecular cytogenetic fingerprinting of esophageal squamous cell carcinoma by comparative genomic hybridization reveals a consistent pattern of chromosomal alterations.
Genes, chromosomes & cancer 1999;25(2):160-8.
1999: Sevilla D Detera-Wadleigh; Judith A Badner; Wade H Berrettini; Takeo Yoshikawa; LR Goldin; G Turner; DY Rollins; Tracy Y Moses; Alan R Sanders; JD Karkera; LE Esterling; J Zeng; Thomas N Ferraro; JJ Guroff; Diane Kazuba; ME Maxwell; John I Nurnberger; Elliot S Gershon
A high-density genome scan detects evidence for a bipolar-disorder susceptibility locus on 13q32 and other potential loci on 1q32 and 18p11.2.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(10):5604-9.
1999: JD Karkera; Kannan V Balan; Takeo Yoshikawa; Timothy O Lipman; Louis Y Korman; A Sharma; R H Patterson; N Sani; Sevilla D Detera-Wadleigh; Robert Wadleigh
Systematic screening of chromosome 18 for loss of heterozygosity in esophageal squamous cell carcinoma.
Cancer genetics and cytogenetics 1999;111(1):81-6.
1998: Raji Grewal; R Cantor; G Turner; R K Grewal; Sevilla D Detera-Wadleigh
Genetic mapping and haplotype analysis of oculopharyngeal muscular dystrophy.
Neuroreport 1998;9(6):961-5.
1998: Elliot S Gershon; Judith A Badner; LR Goldin; Alan R Sanders; A Cravchik; Sevilla D Detera-Wadleigh
Closing in on genes for manic-depressive illness and schizophrenia.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 1998;18(4):233-42.
1998: LE Esterling; Takeo Yoshikawa; G Turner; Judith A Badner; D Bengel; Elliot S Gershon; Wade H Berrettini; Sevilla D Detera-Wadleigh
Serotonin transporter (5-HTT) gene and bipolar affective disorder.
American journal of medical genetics 1998;81(1):37-40.
1998: Takeo Yoshikawa; Alan R Sanders; LE Esterling; Sevilla D Detera-Wadleigh
Multiple transcriptional variants and RNA editing in C18orf1, a novel gene with LDLRA and transmembrane domains on 18p11.2.
Genomics 1998;47(2):246-57.
1997: JD Karkera; S E Taymans; G Turner; Takeo Yoshikawa; Sevilla D Detera-Wadleigh; Robert Wadleigh
Deletion of a consensus oestrogen response element half-site in the glucocorticoid receptor of human multiple myeloma.
British journal of haematology 1997;99(2):372-4.
1997: LE Esterling; T Cox Matise; Alan R Sanders; Takeo Yoshikawa; J Overhauser; Elliot S Gershon; M T Moskowitz; Sevilla D Detera-Wadleigh
An integrated physical map of 18p11.2: a susceptibility region for bipolar disorder.
Molecular psychiatry 1997;2(6):501-4.
1997: Constantine Straturis; Nicholas Sarlis; W H Berrettini; Judith A Badner; George Chrousos; Elliot S Gershon; Sevilla D Detera-Wadleigh
Lack of linkage between the corticotropin-releasing hormone (CRH) gene and bipolar affective disorder.
Molecular psychiatry 1997;2(6):483-5.
1997: Takeo Yoshikawa; G Turner; LE Esterling; Alan R Sanders; Sevilla D Detera-Wadleigh
A novel human myo-inositol monophosphatase gene, IMP.18p, maps to a susceptibility region for bipolar disorder.
Molecular psychiatry 1997;2(5):393-7.
1997: J J M Engelen; LE Esterling; J C M Albrechts; Sevilla D Detera-Wadleigh; Guillaume J J M van Eys
Assignment of the human gene for smoothelin (SMTN) to chromosome 22q12 by fluorescence in situ hybridization and radiation hybrid mapping.
Genomics 1997;43(2):245-7.
1997: O Colin Stine; Francis McMajon; Lieping Chen; Jianfeng Xu; Deborah A Meyers; Dean F MacKinnon; Sylvia G Simpson; Melvin G McInnis; John P Rice; Alison Goate; Theodore Reich; Howard J Edenberg; Tatiana Foroud; John I Nurnberger; Sevilla D Detera-Wadleigh; LR Goldin; JJ Guroff; Elliot S Gershon; MC Blehar; J. Raymond DePaulo
Initial genome screen for bipolar disorder in the NIMH genetics initiative pedigrees: chromosomes 2, 11, 13, 14, and X.
American journal of medical genetics 1997;74(3):263-9.
1997: Sevilla D Detera-Wadleigh; Judith A Badner; Takeo Yoshikawa; Alan R Sanders; LR Goldin; G Turner; DY Rollins; Tracy Y Moses; JJ Guroff; Diane Kazuba; ME Maxwell; Howard J Edenberg; Tatiana Foroud; Debomoy K Lahiri; John I Nurnberger; O Colin Stine; Francis McMajon; Deborah A Meyers; Dean F MacKinnon; Sylvia G Simpson; Melvin G McInnis; J. Raymond DePaulo; J Rice; Alison Goate; Elliot S Gershon
Initial genome scan of the NIMH genetics initiative bipolar pedigrees: chromosomes 4, 7, 9, 18, 19, 20, and 21q.
American journal of medical genetics 1997;74(3):254-62.
1997: John P Rice; Alison Goate; Jeff T Williams; Laura J Bierut; David A Dorr; W Wu; Shantia Shears; G Gopalakrishnan; Howard J Edenberg; Tatiana Foroud; John Nurnberger; Elliot S Gershon; Sevilla D Detera-Wadleigh; LR Goldin; JJ Guroff; Francis McMajon; Sylvia G Simpson; Dean F MacKinnon; Melvin G McInnis; O Colin Stine; J. Raymond DePaulo; MC Blehar; Theodore Reich
Initial genome scan of the NIMH genetics initiative bipolar pedigrees: chromosomes 1, 6, 8, 10, and 12.
American journal of medical genetics 1997;74(3):247-53.
1997: Howard J Edenberg; Tatiana Foroud; P Michael Conneally; JJ Sorbel; Kristie Carr; C Crose; C Willig; Jinghua Zhao; Marvin Miller; Elizabeth Bowman; Aimee R Mayeda; N Leela Rau; Carrie Smiley; John P Rice; Alison Goate; Theodore Reich; O Colin Stine; Francis McMajon; J. Raymond DePaulo; Deborah A Meyers; Sevilla D Detera-Wadleigh; LR Goldin; Elliot S Gershon; MC Blehar; John I Nurnberger
Initial genomic scan of the NIMH genetics initiative bipolar pedigrees: chromosomes 3, 5, 15, 16, 17, and 22.
American journal of medical genetics 1997;74(3):238-46.
1997: Takeo Yoshikawa; Alan R Sanders; LE Esterling; J Overhauser; J A Garnes; G Lennon; R Grewal; Sevilla D Detera-Wadleigh
Isolation of chromosome 18-specific brain transcripts as positional candidates for bipolar disorder.
American journal of medical genetics 1997;74(2):140-9.
1997: SE Taymans; AC DeVries; M B DeVries; Randy J Nelson; T C Friedman; M Castro; Sevilla D Detera-Wadleigh; Carol Sue Carter Porges; George Chrousos
The hypothalamic-pituitary-adrenal axis of prairie voles (Microtus ochrogaster): evidence for target tissue glucocorticoid resistance.
General and comparative endocrinology 1997;106(1):48-61.
1997: T Yoshikawa; Alan R Sanders; Sevilla D Detera-Wadleigh
Contamination of sequence databases with adaptor sequences.
American journal of human genetics 1997;60(2):463-6.
1997: Wade H Berrettini; Thomas N Ferraro; LR Goldin; Sevilla D Detera-Wadleigh; H Choi; D Muniec; JJ Guroff; Diane Kazuba; John I Nurnberger; W T Hsieh; Margret R Hoehe; Elliot S Gershon
A linkage study of bipolar illness.
Archives of general psychiatry 1997;54(1):27-35.
1996: J I García; Guillermo Zalba; Sevilla D Detera-Wadleigh; Carlos De Miguel
Isolation of a cDNA encoding the rat MAP-kinase homolog of human p63mapk.
Mammalian genome : official journal of the International Mammalian Genome Society 1996;7(11):810-4.
1996: Takeo Yoshikawa; Z Brkanac; BR DuPont; G Q Xing; Robin J Leach; Sevilla D Detera-Wadleigh
Assignment of the human nuclear hormone receptor, NUC1 (PPARD), to chromosome 6p21.1-p21.2.
Genomics 1996;35(3):637-8.
1996: Takeo Yoshikawa; BR DuPont; Robin J Leach; Sevilla D Detera-Wadleigh
New variants of the human and rat nuclear hormone receptor, TR4: expression and chromosomal localization of the human gene.
Genomics 1996;35(2):361-6.
1996: Sevilla D Detera-Wadleigh; Judith A Badner; LR Goldin; Wade H Berrettini; Alan R Sanders; D Y Rollins; G Turner; Tracy Y Moses; H Haerian; D Muniec; J I Nurnberger; Elliot S Gershon
Affected-sib-pair analyses reveal support of prior evidence for a susceptibility locus for bipolar disorder, on 21q.
American journal of human genetics 1996;58(6):1279-85.
1996: Takeo Yoshikawa; S Makino; XM Gao; G Q Xing; De-Maw Chuang; Sevilla D Detera-Wadleigh
Splice variants of rat TR4 orphan receptor: differential expression of novel sequences in the 5'-untranslated region and C-terminal domain.
Endocrinology 1996;137(5):1562-71.
1996: Elliot S Gershon; Judith A Badner; Sevilla D Detera-Wadleigh; Thomas N Ferraro; Wade H Berrettini
Maternal inheritance and chromosome 18 allele sharing in unilineal bipolar illness pedigrees.
American journal of medical genetics 1996;67(2):202-7.
1995: G Xing; L Zhang; L Zhang; T Heynen; Takeo Yoshikawa; M Smith; S Weiss; Sevilla D Detera-Wadleigh
Rat PPAR delta contains a CGG triplet repeat and is prominently expressed in the thalamic nuclei.
Biochemical and biophysical research communications 1995;217(3):1015-25.
1995: Takeo Yoshikawa; G Q Xing; Sevilla D Detera-Wadleigh
Detection, simultaneous display and direct sequencing of multiple nuclear hormone receptor genes using bilaterally targeted RNA fingerprinting.
Biochimica et biophysica acta 1995;1264(1):63-71.
1995: Sevilla D Detera-Wadleigh; S W Yoon; Wade H Berrettini; LR Goldin; G Turner; Takeo Yoshikawa; D Y Rollins; D Muniec; J I Nurnberger; Elliot S Gershon
Adrenocorticotropin receptor/melanocortin receptor-2 maps within a reported susceptibility region for bipolar illness on chromosome 18.
American journal of medical genetics 1995;60(4):317-21.
1995: Judith A Badner; S W Yoon; G Turner; T I Bonner; Sevilla D Detera-Wadleigh
Multipoint genetic linkage analysis of the m2 human muscarinic receptor gene.
Mammalian genome : official journal of the International Mammalian Genome Society 1995;6(7):489-90.
1994: Sevilla D Detera-Wadleigh; W T Hsieh; Wade H Berrettini; LR Goldin; D Y Rollins; D Muniec; R Grewal; JJ Guroff; G Turner; D Coffman
Genetic linkage mapping for a susceptibility locus to bipolar illness: chromosomes 2, 3, 4, 7, 9, 10p, 11p, 22, and Xpter.
American journal of medical genetics 1994;54(3):206-18.
1994: Sevilla D Detera-Wadleigh; T G Fanning
Phylogeny of the steroid receptor superfamily.
Molecular phylogenetics and evolution 1994;3(3):192-205.
1994: Wade H Berrettini; Thomas N Ferraro; LR Goldin; D E Weeks; Sevilla D Detera-Wadleigh; J I Nurnberger; Elliot S Gershon
Chromosome 18 DNA markers and manic-depressive illness: evidence for a susceptibility gene.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(13):5918-21.
1993: George Chrousos; Sevilla D Detera-Wadleigh; Michael Karl
Syndromes of glucocorticoid resistance.
Annals of internal medicine 1993;119(11):1113-24.
1993: Michael Karl; S W Lamberts; Sevilla D Detera-Wadleigh; I J Encio; Constantine Straturis; D M Hurley; D Accili; George Chrousos
Familial glucocorticoid resistance caused by a splice site deletion in the human glucocorticoid receptor gene.
The Journal of clinical endocrinology and metabolism 1993;76(3):683-9.
1992: Sevilla D Detera-Wadleigh; Wade H Berrettini; LR Goldin; Maria Martinez; W T Hsieh; Margret R Hoehe; I J Encio; D Coffman; D Y Rollins; D Muniec
A systematic search for a bipolar predisposing locus on chromosome 5.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 1992;6(4):219-29.
1992: R P Grewal; Maria Martinez; Margret R Hoehe; Tom Bonner; Elliot S Gershon; Sevilla D Detera-Wadleigh
Genetic linkage mapping of the m4 human muscarinic receptor (CHRM4).
Genomics 1992;13(1):239-40.
1991: Carlos De Miguel; D Kligman; J Patel; Sevilla D Detera-Wadleigh
Molecular analysis of microtubule-associated protein-2 kinase cDNA from mouse and rat brain.
DNA and cell biology 1991;10(7):505-14.
1991: Sevilla D Detera-Wadleigh; I J Encio; D Y Rollins; D Coffman; D Wiesch
A TthIII1 polymorphism on the 5' flanking region of the glucocorticoid receptor gene (GRL).
Nucleic acids research 1991;19(8):1960.
1991: I J Encío; Sevilla D Detera-Wadleigh
The genomic structure of the human glucocorticoid receptor.
The Journal of biological chemistry 1991;266(11):7182-8.
1991: Robert Wadleigh; C S Chan; M H Cohen; S H Krasnow; A Anderson; Sevilla D Detera-Wadleigh
H-ras-1 polymorphism in leukemia.
American journal of hematology 1991;36(1):69-70.
1990: Pablo V Gejman; Sevilla D Detera-Wadleigh; M M Martinez; Wade H Berrettini; LR Goldin; Joel Gelernter; W T Hsieh; Elliot S Gershon
Manic depressive illness not linked to factor IX region in an independent series of pedigrees.
Genomics 1990;8(4):648-55.
1990: Wade H Berrettini; LR Goldin; Joel Gelernter; Pablo V Gejman; Elliot S Gershon; Sevilla D Detera-Wadleigh
X-chromosome markers and manic-depressive illness. Rejection of linkage to Xq28 in nine bipolar pedigrees.
Archives of general psychiatry 1990;47(4):366-73.
1989: Sevilla D Detera-Wadleigh; D Coffman; T Shimada
A frequent DHFR polymorphism detected by an intron fragment.
Nucleic acids research 1989;17(15):6432.
1989: Sevilla D Detera-Wadleigh; D Wiesch; Tom Bonner
An SstI polymorphism for the human muscarinic acetylcholine receptor gene, m4 (CHRM 4).
Nucleic acids research 1989;17(15):6431.
1989: Sevilla D Detera-Wadleigh; LR Goldin; Robin Sherrington; I Encio; Carlos De Miguel; Wade H Berrettini; Hugh M D Gurling; Elliot S Gershon
Exclusion of linkage to 5q11-13 in families with schizophrenia and other psychiatric disorders.
Nature 1989;340(6232):391-3.
1989: B Sen Gupta; Sevilla D Detera-Wadleigh; O W McBride; Felix Friedberg
A calmodulin pseudogene on human chromosome 17.
Nucleic acids research 1989;17(7):2868.
1988: Carlos De Miguel; Tom Bonner; Sevilla D Detera-Wadleigh
RFLPs associated with the substance P-neurokinin A gene (NKNA).
Nucleic acids research 1988;16(4):1644.
1987: B SenGupta; Felix Friedberg; Sevilla D Detera-Wadleigh
Molecular analysis of human and rat calmodulin complementary DNA clones. Evidence for additional active genes in these species.
The Journal of biological chemistry 1987;262(34):16663-70.
1987: Sevilla D Detera-Wadleigh; Carlos De Miguel; Wade H Berrettini; L E DeLisi; LR Goldin; Elliot S Gershon
Neuropeptide gene polymorphisms in affective disorder and schizophrenia.
Journal of psychiatric research 1987;21(4):581-7.