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Michael Detmar

Research Profile

Living Beings

Chemicals & Drugs

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Lymphangiogenesis

Anatomy

Disorders

Neovascularization, Pathologic

Physiology

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Publications

TOP 3
Steven T Proulx; Matthias Rinderknecht; Katrin S Blum; Ailsa Christiansen; Sinem Karaman; Jean-Christophe Leroux; Paola Luciani; Michael Detmar
Use of a PEG-conjugated bright near-infrared dye for functional imaging of rerouting of tumor lymphatic drainage after sentinel lymph node metastasis.
Katrin S Blum; Jean-Christophe Leroux; Paola Luciani; Steven T Proulx; Michael Detmar
Dynamics of lymphatic regeneration and flow patterns after lymph node dissection.
Silvana Zgraggen; Alexandra M Ochsenbein; Michael Detmar
An important role of blood and lymphatic vessels in inflammation and allergy.

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All Publications

2013: Steven T Proulx; Matthias Rinderknecht; Katrin S Blum; Ailsa Christiansen; Sinem Karaman; Jean-Christophe Leroux; Paola Luciani; Michael Detmar
Use of a PEG-conjugated bright near-infrared dye for functional imaging of rerouting of tumor lymphatic drainage after sentinel lymph node metastasis.
Biomaterials 2013;34(21):5128-37.
2013: Katrin S Blum; Jean-Christophe Leroux; Paola Luciani; Steven T Proulx; Michael Detmar
Dynamics of lymphatic regeneration and flow patterns after lymph node dissection.
Breast cancer research and treatment 2013;139(1):81-6.
2013: Silvana Zgraggen; Alexandra M Ochsenbein; Michael Detmar
An important role of blood and lymphatic vessels in inflammation and allergy.
Journal of allergy 2013;2013():672381.
2013: Viviane Mumprecht; Michael Detmar
In vivo imaging of lymph node lymphangiogenesis by immuno-positron emission tomography.
Methods in molecular biology (Clifton, N.J.) 2013;961():129-40.
2012: A Alitalo; Michael Detmar
Interaction of tumor cells and lymphatic vessels in cancer progression.
Oncogene 2012;31(42):4499-508.
2012: Martin Michael Peter Schulz; Don Yuen; Silvana Zgraggen; Lu Chen; Stephanie Fischer; Gyeong Jin Kang; Felix Reisen; Gisbert Schneider; Michael Detmar
Phenotype-based high-content chemical library screening identifies statins as inhibitors of in vivo lymphangiogenesis.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(40):E2665-74.
2012: Giorgia Jurisic; Sinem Karaman; Hélène Maby-El Hajjami; Carlos Ochoa Pereira; Alexandra M Ochsenbein; Tatiana V Petrova; Shoib S Siddiqui; Annamari Alitalo; Michael Detmar
An unexpected role of semaphorin3a-neuropilin-1 signaling in lymphatic vessel maturation and valve formation.
Circulation research 2012;111(4):426-36.
2012: Tam Duong; Michael Detmar; Peter Koopman; Jean-Christophe Leroux; Paola Luciani; Steven T Proulx; Mathias Francois
Genetic ablation of SOX18 function suppresses tumor lymphangiogenesis and metastasis of melanoma in mice.
Cancer research 2012;72(12):3105-14.
2012: Fabienne Niederer; Caroline Ospelt; Joanna Stanczyk; Michelle Trenkmann; Michael Detmar; Renate E Gay; Steffen GAY; Astrid Jüngel; Emmanuel Karouzakis; Christoph Kolling; Michel Neidhart; Diego Kyburz
Down-regulation of microRNA-34a* in rheumatoid arthritis synovial fibroblasts promotes apoptosis resistance.
Arthritis and rheumatism 2012;64(6):1771-9.
2012: Viviane Mumprecht; Filip Roudnicky; Michael Detmar
Inflammation-induced lymph node lymphangiogenesis is reversible.
The American journal of pathology 2012;180(3):874-9.
2012: Alexander Kanitz; Adriana Primorac; Piotr J Dziunycz; Alessia Galgano; André P Gerber; Günther F L Hofbauer; Jochen Imig; Michael Detmar
The expression levels of microRNA-361-5p and its target VEGFA are inversely correlated in human cutaneous squamous cell carcinoma.
PloS one 2012;7(11):e49568.
2012: Yong Chen; Ruediger Liersch; Michael Detmar
The miR-290-295 cluster suppresses autophagic cell death of melanoma cells.
Scientific reports 2012;2():808.
2011: Ailsa Christiansen; Michael Detmar
Lymphangiogenesis and cancer.
Genes & cancer 2011;2(12):1146-58.
2011: Reto Huggenberger; Michael Detmar
The cutaneous vascular system in chronic skin inflammation.
The journal of investigative dermatology. Symposium proceedings / the Society for Investigative Dermatology, Inc. [and] European Society for Dermatological Research 2011;15(1):24-32.
2011: Fabienne Niederer; Caroline Ospelt; Fabia Brentano; Michael Detmar; Renate E Gay; Steffen GAY; Michael O Hottiger; Diego Kyburz
SIRT1 overexpression in the rheumatoid arthritis synovium contributes to proinflammatory cytokine production and apoptosis resistance.
Annals of the rheumatic diseases 2011;70(10):1866-73.
2011: Daniela Marino; Vasilios Dabouras; André W Brändli; Michael Detmar
A role for all-trans-retinoic acid in the early steps of lymphatic vasculature development.
Journal of vascular research 2011;48(3):236-51.
2010: Leah N Cueni; Lu Chen; Hui Zhang; Daniela Marino; Reto Huggenberger; Annamari Alitalo; Roberta Bianchi; Michael Detmar
Podoplanin-Fc reduces lymphatic vessel formation in vitro and in vivo and causes disseminated intravascular coagulation when transgenically expressed in the skin.
Blood 2010;116(20):4376-84.
2010: Viviane Mumprecht; Michael Honer; Benjamin Vigl; Steven T Proulx; Eveline Trachsel; Manuela Kaspar; Nadja E Banziger-Tobler; Roger Schibli; Dario Neri; Michael Detmar
In vivo imaging of inflammation- and tumor-induced lymph node lymphangiogenesis by immuno-positron emission tomography.
Cancer research 2010;70(21):8842-51.
2010: Giorgia Jurisic; Maria Iolyeva; Steven T Proulx; Cornelia Halin; Michael Detmar
Thymus cell antigen 1 (Thy1, CD90) is expressed by lymphatic vessels and mediates cell adhesion to lymphatic endothelium.
Experimental cell research 2010;316(17):2982-92.
2010: Reto Huggenberger; Stefan Ullmann; Steven T Proulx; Bronislaw Pytowski; Kari Alitalo; Michael Detmar
Stimulation of lymphangiogenesis via VEGFR-3 inhibits chronic skin inflammation.
The Journal of experimental medicine 2010;207(10):2255-69.
2010: Steven T Proulx; Paola Luciani; Stefanie Derzsi; Matthias Rinderknecht; Viviane Mumprecht; Jean-Christophe Leroux; Michael Detmar
Quantitative imaging of lymphatic function with liposomal indocyanine green.
Cancer research 2010;70(18):7053-62.
2010: Leah N Cueni; Ivan Hegyi; Jay W Shin; Andrea Albinger-Hegyi; Silke Gruber; Rainer Kunstfeld; Holger Moch; Michael Detmar
Tumor lymphangiogenesis and metastasis to lymph nodes induced by cancer cell expression of podoplanin.
The American journal of pathology 2010;177(2):1004-16.
2010: Deena M Leslie Pedrioli; Terhi Karpanen; Vasilios Dabouras; Giorgia Jurisic; Glenn van de Hoek; Jay W Shin; Daniela Marino; Roland E Kälin; Sebastian Leidel; Paolo Cinelli; Stefan Schulte-Merker; André W Brändli; Michael Detmar
miR-31 functions as a negative regulator of lymphatic vascular lineage-specific differentiation in vitro and vascular development in vivo.
Molecular and cellular biology 2010;30(14):3620-34.
2010: Matthias Rinderknecht; Alessandra Villa; Kurt Ballmer-Hofer; Dario Neri; Michael Detmar
Phage-derived fully human monoclonal antibody fragments to human vascular endothelial growth factor-C block its interaction with VEGF receptor-2 and 3.
PloS one 2010;5(8):e11941.
2009: Viviane Mumprecht; Michael Detmar
Lymphangiogenesis and cancer metastasis.
Journal of cellular and molecular medicine 2009;13(8A):1405-16.
2009: Paula Velasco; Rainer Huegel; Jochen Brasch; Jens M Schröder; Michael Weichenthal; Eggert Stockfleth; Thomas Schwarz; Jack Lawler; Michael Detmar; Bernhard Lange-Asschenfeldt
The angiogenesis inhibitor thrombospondin-1 inhibits acute cutaneous hypersensitivity reactions.
The Journal of investigative dermatology 2009;129(8):2022-30.
2009: Roland E Kälin; Nadja E Bänziger-Tobler; Michael Detmar; André W Brändli
An in vivo chemical library screen in Xenopus tadpoles reveals novel pathways involved in angiogenesis and lymphangiogenesis.
Blood 2009;114(5):1110-22.
2009: Katie Doeden; Zhihai Ma; Balasubramanian Narasimhan; Susan M Swetter; Michael Detmar; Soheil S Dadras
Lymphatic invasion in cutaneous melanoma is associated with sentinel lymph node metastasis.
Journal of cutaneous pathology 2009;36(7):772-80.
2009: Leah N Cueni; Michael Detmar
Galectin-8 interacts with podoplanin and modulates lymphatic endothelial cell functions.
Experimental cell research 2009;315(10):1715-23.
2009: Kentaro Kajiya; Mika Sawane; Reto Huggenberger; Michael Detmar
Activation of the VEGFR-3 pathway by VEGF-C attenuates UVB-induced edema formation and skin inflammation by promoting lymphangiogenesis.
The Journal of investigative dermatology 2009;129(5):1292-8.
2009: Tobias Gebäck; Martin Michael Peter Schulz; Petros Koumoutsakos; Michael Detmar
TScratch: a novel and simple software tool for automated analysis of monolayer wound healing assays.
BioTechniques 2009;46(4):265-74.
2009: Benjamin Vigl; Claudia Zgraggen; Nadia Rehman; Nadia E Banziger-Tobler; Michael Detmar; Cornelia Halin
Coxsackie- and adenovirus receptor (CAR) is expressed in lymphatic vessels in human skin and affects lymphatic endothelial cell function in vitro.
Experimental cell research 2009;315(2):336-47.
2009: Giorgia Jurisic; Michael Detmar
Lymphatic endothelium in health and disease.
Cell and tissue research 2009;335(1):97-108.
2008: Soheil S Dadras; Adrienne Skrzypek; Lynh Nguyen; Jay W Shin; Martin M P Schulz; Jack Arbiser; Martin C Mihm; Michael Detmar
Prox-1 promotes invasion of kaposiform hemangioendotheliomas.
The Journal of investigative dermatology 2008;128(12):2798-806.
2008: Jay W Shin; Giorgia Jurisic; Michael Detmar
Lymphatic-specific expression of dipeptidyl peptidase IV and its dual role in lymphatic endothelial function.
Experimental cell research 2008;314(16):3048-56.
2008: Jay W Shin; Reto Huggenberger; Michael Detmar
Transcriptional profiling of VEGF-A and VEGF-C target genes in lymphatic endothelium reveals endothelial-specific molecule-1 as a novel mediator of lymphangiogenesis.
Blood 2008;112(6):2318-26.
2008: Nadja Erika Banziger-Tobler; Cornelia Halin; Kentaro Kajiya; Michael Detmar
Growth hormone promotes lymphangiogenesis.
The American journal of pathology 2008;173(2):586-97.
2008: Matthias Rinderknecht; Michael Detmar
Tumor lymphangiogenesis and melanoma metastasis.
Journal of cellular physiology 2008;216(2):347-54.
2008: Cornelia Halin; Hermann Fahrngruber; Josef G Meingassner; Guido Bold; Amanda Littlewood-Evans; Anton Stuetz; Michael Detmar
Inhibition of chronic and acute skin inflammation by treatment with a vascular endothelial growth factor receptor tyrosine kinase inhibitor.
The American journal of pathology 2008;173(1):265-77.
2008: Christoph Roesli; Viviane Mumprecht; Dario Neri; Michael Detmar
Identification of the surface-accessible, lineage-specific vascular proteome by two-dimensional peptide mapping.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2008;22(6):1933-44.
2008: Joanna Stanczyk; Deena M Leslie Pedrioli; Fabia Brentano; Olga Sanchez-Pernaute; Christoph Kolling; Renate E Gay; Michael Detmar; Steffen Gay; Diego Kyburz
Altered expression of MicroRNA in synovial fibroblasts and synovial tissue in rheumatoid arthritis.
Arthritis and rheumatism 2008;58(4):1001-9.
2008: Kentaro Kajiya; Reto Huggenberger; Ines Drinnenberg; Beijia Ma; Michael Detmar
Nitric oxide mediates lymphatic vessel activation via soluble guanylate cyclase alpha1beta1-impact on inflammation.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2008;22(2):530-7.
2008: Leah N Cueni; Michael Detmar
The lymphatic system in health and disease.
Lymphatic research and biology 2008;6(3-4):109-22.
2008: Cornelia Halin; Michael Detmar
Chapter 1. Inflammation, angiogenesis, and lymphangiogenesis.
Methods in enzymology 2008;445():1-25.
2007: Cornelia Halin; Nadja E Tobler; Benjamin Vigl; Lawrence F Brown; Michael Detmar
VEGF-A produced by chronically inflamed tissue induces lymphangiogenesis in draining lymph nodes.
Blood 2007;110(9):3158-67.
2007: Kentaro Kajiya; Rainer Kunstfeld; Michael Detmar; Jin Ho Chung
Reduction of lymphatic vessels in photodamaged human skin.
Journal of dermatological science 2007;47(3):241-3.
2007: Ruediger Liersch; Michael Detmar
Lymphangiogenesis in development and disease.
Thrombosis and haemostasis 2007;98(2):304-10.
2007: Eveline Trachsel; Manuela Kaspar; Frank Bootz; Michael Detmar; Dario Neri
A human mAb specific to oncofetal fibronectin selectively targets chronic skin inflammation in vivo.
The Journal of investigative dermatology 2007;127(4):881-6.
2007: Satoshi Hirakawa; Lawrence F Brown; Shohta Kodama; Karri Paavonen; Kari Alitalo; Michael Detmar
VEGF-C-induced lymphangiogenesis in sentinel lymph nodes promotes tumor metastasis to distant sites.
Blood 2007;109(3):1010-7.
2006: Christoph Wissmann; Michael Detmar
Pathways targeting tumor lymphangiogenesis.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(23):6865-8.
2006: Kentaro Kajiya; Satoshi Hirakawa; Michael Detmar
Vascular endothelial growth factor-A mediates ultraviolet B-induced impairment of lymphatic vessel function.
The American journal of pathology 2006;169(4):1496-503.
2006: Leah N Cueni; Michael Detmar
New insights into the molecular control of the lymphatic vascular system and its role in disease.
The Journal of investigative dermatology 2006;126(10):2167-77.
2006: Nadja E Tobler; Michael Detmar
Tumor and lymph node lymphangiogenesis--impact on cancer metastasis.
Journal of leukocyte biology 2006;80(4):691-6.
2006: Kentaro Kajiya; Michael Detmar
An important role of lymphatic vessels in the control of UVB-induced edema formation and inflammation.
The Journal of investigative dermatology 2006;126(4):919-21.
2006: Cornelia Halin; Michael Detmar
An unexpected connection: lymph node lymphangiogenesis and dendritic cell migration.
Immunity 2006;24(2):129-31.
2006: Helen S Young; Angela M Summers; Ian R Read; David A Fairhurst; Darren Plant; Emanuela Campalani; Catherine H Smith; J N W N Barker; Michael Detmar; Paul E C Brenchley; Christopher E M Griffiths
Interaction between genetic control of vascular endothelial growth factor production and retinoid responsiveness in psoriasis.
The Journal of investigative dermatology 2006;126(2):453-9.
2006: Jay W Shin; Michael Min; Fréderic Larrieu-Lahargue; Xavier Canron; Rainer Kunstfeld; Lynh Nguyen; Janet E Henderson; Andreas Bikfalvi; Michael Detmar; Young Kwon Hong
Prox1 promotes lineage-specific expression of fibroblast growth factor (FGF) receptor-3 in lymphatic endothelium: a role for FGF signaling in lymphangiogenesis.
Molecular biology of the cell 2006;17(2):576-84.
2006: Ruediger Liersch; Filip Nay; Lingge Lu; Michael Detmar
Induction of lymphatic endothelial cell differentiation in embryoid bodies.
Blood 2006;107(3):1214-6.
2005: Soheil S Dadras; Bernhard Lange-Asschenfeldt; Paula Velasco; Lynh Nguyen; Anish Vora; Alona Muzikansky; Katharina Jahnke; Axel Hauschild; Satoshi Hirakawa; Martin C Mihm; Michael Detmar
Tumor lymphangiogenesis predicts melanoma metastasis to sentinel lymph nodes.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2005;18(9):1232-42.
2005: Kentaro Kajiya; Satoshi Hirakawa; Beijia Ma; Ines Drinnenberg; Michael Detmar
Hepatocyte growth factor promotes lymphatic vessel formation and function.
The EMBO journal 2005;24(16):2885-95.
2005: Satoshi Hirakawa; Shohta Kodama; Rainer Kunstfeld; Kentaro Kajiya; Lawrence F Brown; Michael Detmar
VEGF-A induces tumor and sentinel lymph node lymphangiogenesis and promotes lymphatic metastasis.
The Journal of experimental medicine 2005;201(7):1089-99.
2005: Satoshi Hirakawa; Seishiro Fujii; Kentaro Kajiya; Kiichiro Yano; Michael Detmar
Vascular endothelial growth factor promotes sensitivity to ultraviolet B-induced cutaneous photodamage.
Blood 2005;105(6):2392-9.
2005: Vivien Schacht; Soheil S Dadras; Louise A Johnson; David G Jackson; Young Kwon Hong; Michael Detmar
Up-regulation of the lymphatic marker podoplanin, a mucin-type transmembrane glycoprotein, in human squamous cell carcinomas and germ cell tumors.
The American journal of pathology 2005;166(3):913-21.
2005: Roni Mamluk; Michael Klagsbrun; Michael Detmar; Diane R Bielenberg
Soluble neuropilin targeted to the skin inhibits vascular permeability.
Angiogenesis 2005;8(3):217-27.
2005: Kiichiro Yano; K Kadoya; Kentaro Kajiya; Y-K Hong; Michael Detmar
Ultraviolet B irradiation of human skin induces an angiogenic switch that is mediated by upregulation of vascular endothelial growth factor and by downregulation of thrombospondin-1.
The British journal of dermatology 2005;152(1):115-21.
2004: Yong Wook Park; Young Mo Kang; Joe Butterfield; Michael Detmar; Jörg J Goronzy; Cornelia M Weyand
Thrombospondin 2 functions as an endogenous regulator of angiogenesis and inflammation in rheumatoid arthritis.
The American journal of pathology 2004;165(6):2087-98.
2004: Michael Shin; Kant Matsuda; Osamu Ishii; Hidetomi Terai; Mohammad MR Kaazempur-Mofrad; Jeffrey Borenstein; Michael Detmar; Joseph P Vacanti
Endothelialized networks with a vascular geometry in microfabricated poly(dimethyl siloxane).
Biomedical microdevices 2004;6(4):269-78.
2004: Young Kwon Hong; Jay W Shin; Michael Detmar
Development of the lymphatic vascular system: a mystery unravels.
Developmental dynamics : an official publication of the American Association of Anatomists 2004;231(3):462-73.
2004: Soheil S Dadras; Michael Detmar
Angiogenesis and lymphangiogenesis of skin cancers.
Hematology/oncology clinics of North America 2004;18(5):1059-70, viii.
2004: Soheil S Dadras; Paula E North; Jennifer Bertoncini; Martin C Mihm; Michael Detmar
Infantile hemangiomas are arrested in an early developmental vascular differentiation state.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2004;17(9):1068-79.
2004: Rainer Kunstfeld; Satoshi Hirakawa; Young Kwon Hong; Vivien Schacht; Bernhard Lange-Asschenfeldt; Paula Velasco; Charles Lin; Edda Fiebiger; Xunbin Wei; Yan Wu; Daniel J Hicklin; Peter Bohlen; Michael Detmar
Induction of cutaneous delayed-type hypersensitivity reactions in VEGF-A transgenic mice results in chronic skin inflammation associated with persistent lymphatic hyperplasia.
Blood 2004;104(4):1048-57.
2004: Karen O Yee; Michael Streit; Thomas Hawighorst; Michael Detmar; Jack Lawler
Expression of the type-1 repeats of thrombospondin-1 inhibits tumor growth through activation of transforming growth factor-beta.
The American journal of pathology 2004;165(2):541-52.
2004: Young Kwon Hong; Kimberly E Foreman; Jay W Shin; Satoshi Hirakawa; Christine L Curry; David R Sage; Towia Libermann; Bruce J Dezube; Joyce Diane Fingeroth; Michael Detmar
Lymphatic reprogramming of blood vascular endothelium by Kaposi sarcoma-associated herpesvirus.
Nature genetics 2004;36(7):683-5.
2004: Young Kwon Hong; Bernhard Lange-Asschenfeldt; Paula Velasco; Satoshi Hirakawa; Rainer Kunstfeld; Lawrence F Brown; Peter Bohlen; Donald R Senger; Michael Detmar
VEGF-A promotes tissue repair-associated lymphatic vessel formation via VEGFR-2 and the alpha1beta1 and alpha2beta1 integrins.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2004;18(10):1111-3.
2004: Satoshi Hirakawa; Michael Detmar
New insights into the biology and pathology of the cutaneous lymphatic system.
Journal of dermatological science 2004;35(1):1-8.
2004: Jonathan Wilkin; Mark Dahl; Michael Detmar; Lynn Drake; Matthew H Liang; Richard Odom; Frank Powell
Standard grading system for rosacea: report of the National Rosacea Society Expert Committee on the classification and staging of rosacea.
Journal of the American Academy of Dermatology 2004;50(6):907-12.
2004: Jack Lawler; Michael Detmar
Tumor progression: the effects of thrombospondin-1 and -2.
The international journal of biochemistry & cell biology 2004;36(6):1038-45.
2004: Paula E North; Teri Kahn; Maria R Cordisco; Soheil S Dadras; Michael Detmar; Ilona J Frieden
Multifocal lymphangioendotheliomatosis with thrombocytopenia: a newly recognized clinicopathological entity.
Archives of dermatology 2004;140(5):599-606.
2004: Michael Detmar
Evidence for vascular endothelial growth factor (VEGF) as a modifier gene in psoriasis.
The Journal of investigative dermatology 2004;122(1):xiv-xv.
2004: Kiichiro Yano; Kentaro Kajiya; Miki Ishiwata; Young Kwon Hong; Tokichi Miyakawa; Michael Detmar
Ultraviolet B-induced skin angiogenesis is associated with a switch in the balance of vascular endothelial growth factor and thrombospondin-1 expression.
The Journal of investigative dermatology 2004;122(1):201-8.
2003: Yun-Hee Noh; Kant Matsuda; Young Kwon Hong; Rainer Kunstfeld; Lucia Riccardi; Manuel Koch; Hajimu Oura; Soheil S Dadras; Michael Streit; Michael Detmar
An N-terminal 80 kDa recombinant fragment of human thrombospondin-2 inhibits vascular endothelial growth factor induced endothelial cell migration in vitro and tumor growth and angiogenesis in vivo.
The Journal of investigative dermatology 2003;121(6):1536-43.
2003: Yoko Yahata; Yuji Shirakata; Sho Tokumaru; Kenshi Yamasaki; Koji Sayama; Yasushi Hanakawa; Michael Detmar; Koji Hashimoto
Nuclear translocation of phosphorylated STAT3 is essential for vascular endothelial growth factor-induced human dermal microvascular endothelial cell migration and tube formation.
The Journal of biological chemistry 2003;278(41):40026-31.
2003: Young Kwon Hong; Michael Detmar
Prox1, master regulator of the lymphatic vasculature phenotype.
Cell and tissue research 2003;314(1):85-92.
2003: Vivien Schacht; Maria I Ramirez; Young Kwon Hong; Satoshi Hirakawa; Dian Feng; Natasha Harvey; Mary Williams; Ann M Dvorak; Harold F Dvorak; Guillermo Oliver; Michael Detmar
T1alpha/podoplanin deficiency disrupts normal lymphatic vasculature formation and causes lymphedema.
The EMBO journal 2003;22(14):3546-56.
2003: Yu-Ping Xia; Baosheng Li; Donna Hylton; Michael Detmar; George D Yancopoulos; John S Rudge
Transgenic delivery of VEGF to mouse skin leads to an inflammatory condition resembling human psoriasis.
Blood 2003;102(1):161-8.
2003: Soheil S Dadras; Thomas Paul; Jennifer Bertoncini; Lawrence F Brown; Alona Muzikansky; David G Jackson; Ulf Ellwanger; Claus Garbe; Martin C Mihm; Michael Detmar
Tumor lymphangiogenesis: a novel prognostic indicator for cutaneous melanoma metastasis and survival.
The American journal of pathology 2003;162(6):1951-60.
2003: Michael Streit; Michael Detmar
Angiogenesis, lymphangiogenesis, and melanoma metastasis.
Oncogene 2003;22(20):3172-9.
2003: Claus J Gruss; Kapaettu Satyamoorthy; Carola Berking; John Lininger; Mark Nesbit; Helmut Schaider; Zhao-Jun Liu; Masahiro Oka; Mei-Yu Hsu; Takashi Shirakawa; Gang Li; Thomas Bogenrieder; Peter Carmeliet; Wafik S El-Deiry; Stephen L Eck; Justi S Rao; Andrew H Baker; Jean T Bennet; Timothy M Crombleholme; Omaida Velazquez; Jagajan Karmacharya; David J Margolis; James M Wilson; Michael Detmar; Mihaela Skobe; Paul D Robbins; Clayton Buck; Meenhard Herlyn
Stroma formation and angiogenesis by overexpression of growth factors, cytokines, and proteolytic enzymes in human skin grafted to SCID mice.
The Journal of investigative dermatology 2003;120(4):683-92.
2003: Satoshi Hirakawa; Young Kwon Hong; Natasha Harvey; Vivien Schacht; Kant Matsuda; Towia Libermann; Michael Detmar
Identification of vascular lineage-specific genes by transcriptional profiling of isolated blood vascular and lymphatic endothelial cells.
The American journal of pathology 2003;162(2):575-86.
2003: Hajimu Oura; Jennifer Bertoncini; Paula Velasco; Lawrence F Brown; Peter Carmeliet; Michael Detmar
A critical role of placental growth factor in the induction of inflammation and edema formation.
Blood 2003;101(2):560-7.
2003: Kiichiro Yano; Lawrence F Brown; Jack Lawler; Tokichi Miyakawa; Michael Detmar
Thrombospondin-1 plays a critical role in the induction of hair follicle involution and vascular regression during the catagen phase.
The Journal of investigative dermatology 2003;120(1):14-9.
2002: Janice A Nagy; Eliza Vasile; Dian Feng; Christian Sundberg; Lawrence F Brown; Michael Detmar; Joel Lawitts; Laura Benjamin; Xiaolian Tan; Eleanor J Manseau; Ann M Dvorak; Harold F Dvorak
Vascular permeability factor/vascular endothelial growth factor induces lymphangiogenesis as well as angiogenesis.
The Journal of experimental medicine 2002;196(11):1497-506.
2002: Thomas Hawighorst; Hajimu Oura; Michael Streit; Lauren Janes; Lynh Nguyen; Lawrence F Brown; Guillermo Oliver; David G Jackson; Michael Detmar
Thrombospondin-1 selectively inhibits early-stage carcinogenesis and angiogenesis but not tumor lymphangiogenesis and lymphatic metastasis in transgenic mice.
Oncogene 2002;21(52):7945-56.
2002: Jin Ho Chung; Kiichiro Yano; Mi Kyung Lee; Choon Shik Youn; Jin Young Seo; Kyu Han Kim; Kwang Hyun Cho; Hee Chul Eun; Michael Detmar
Differential effects of photoaging vs intrinsic aging on the vascularization of human skin.
Archives of dermatology 2002;138(11):1437-42.
2002: Young Kwon Hong; Natasha Harvey; Yun-Hee Noh; Vivien Schacht; Satoshi Hirakawa; Michael Detmar; Guillermo Oliver
Prox1 is a master control gene in the program specifying lymphatic endothelial cell fate.
Developmental dynamics : an official publication of the American Association of Anatomists 2002;225(3):351-7.
2002: Michael Detmar; Satoshi Hirakawa
The formation of lymphatic vessels and its importance in the setting of malignancy.
The Journal of experimental medicine 2002;196(6):713-8.
2002: Kiichiro Yano; Hajimu Oura; Michael Detmar
Targeted overexpression of the angiogenesis inhibitor thrombospondin-1 in the epidermis of transgenic mice prevents ultraviolet-B-induced angiogenesis and cutaneous photo-damage.
The Journal of investigative dermatology 2002;118(5):800-5.
2002: Jeffrey T Wigle; Natasha Harvey; Michael Detmar; Irina Lagutina; Gerard C Grosveld; Michael D Gunn; David G Jackson; Guillermo Oliver
An essential role for Prox1 in the induction of the lymphatic endothelial cell phenotype.
The EMBO journal 2002;21(7):1505-13.
2002: Christian Sundberg; Marcin Kowanetz; Lawrence F Brown; Michael Detmar; Harold F Dvorak
Stable expression of angiopoietin-1 and other markers by cultured pericytes: phenotypic similarities to a subpopulation of cells in maturing vessels during later stages of angiogenesis in vivo.
Laboratory investigation; a journal of technical methods and pathology 2002;82(4):387-401.
2002: Thomas Hawighorst; Mihaela Skobe; Michael Streit; Young Kwon Hong; Paula Velasco; Lawrence F Brown; Lucia Riccardi; Bernhard Lange-Asschenfeldt; Michael Detmar
Activation of the tie2 receptor by angiopoietin-1 enhances tumor vessel maturation and impairs squamous cell carcinoma growth.
The American journal of pathology 2002;160(4):1381-92.
2002: Guillermo Oliver; Michael Detmar
The rediscovery of the lymphatic system: old and new insights into the development and biological function of the lymphatic vasculature.
Genes & development 2002;16(7):773-83.
2002: Michael Streit; Antonia E Stephen; Thomas Hawighorst; Kant Matsuda; Bernhard Lange-Asschenfeldt; Lawrence F Brown; Joseph P Vacanti; Michael Detmar
Systemic inhibition of tumor growth and angiogenesis by thrombospondin-2 using cell-based antiangiogenic gene therapy.
Cancer research 2002;62(7):2004-12.
2002: Jonathan Wilkin; Mark Dahl; Michael Detmar; Lynn Drake; Alvan Feinstein; Richard Odom; Frank Powell
Standard classification of rosacea: Report of the National Rosacea Society Expert Committee on the Classification and Staging of Rosacea.
Journal of the American Academy of Dermatology 2002;46(4):584-7.
2002: Bernhard Lange-Asschenfeldt; Wolfgang Weninger; Paula Velasco; Themis R Kyriakides; Ulrich H von Andrian; Paul Bornstein; Michael Detmar
Increased and prolonged inflammation and angiogenesis in delayed-type hypersensitivity reactions elicited in the skin of thrombospondin-2--deficient mice.
Blood 2002;99(2):538-45.
2002: Donald R Senger; Carole A Perruzzi; Michael Streit; Victor E Koteliansky; Antonin R de Fougerolles; Michael Detmar
The alpha(1)beta(1) and alpha(2)beta(1) integrins provide critical support for vascular endothelial growth factor signaling, endothelial cell migration, and tumor angiogenesis.
The American journal of pathology 2002;160(1):195-204.
2001: Bernhard Lange-Asschenfeldt; Paula Velasco; Michael Streit; Thomas Hawighorst; Sandra E Pike; Giovanna Tosato; Michael Detmar
The angiogenesis inhibitor vasostatin does not impair wound healing at tumor-inhibiting doses.
The Journal of investigative dermatology 2001;117(5):1036-41.
2001: Mihaela Skobe; Leena M Hamberg; Thomas Hawighorst; M Schirner; G L Wolf; Kari Alitalo; Michael Detmar
Concurrent induction of lymphangiogenesis, angiogenesis, and macrophage recruitment by vascular endothelial growth factor-C in melanoma.
The American journal of pathology 2001;159(3):893-903.
2001: Thomas Hawighorst; Paula Velasco; Michael Streit; Young Kwon Hong; Themis R Kyriakides; Lawrence F Brown; Paul Bornstein; Michael Detmar
Thrombospondin-2 plays a protective role in multistep carcinogenesis: a novel host anti-tumor defense mechanism.
The EMBO journal 2001;20(11):2631-40.
2001: K Yano; Lawrence F Brown; Michael Detmar
Control of hair growth and follicle size by VEGF-mediated angiogenesis.
The Journal of clinical investigation 2001;107(4):409-17.
2001: Mihaela Skobe; Thomas Hawighorst; David G Jackson; Remko Prevo; Lauren Janes; Paula Velasco; Lucia Riccardi; Kari Alitalo; Kevin P Claffey; Michael Detmar
Induction of tumor lymphangiogenesis by VEGF-C promotes breast cancer metastasis.
Nature medicine 2001;7(2):192-8.
2001: F Echtermeyer; M Streit; Sarah Wilcox-Adelman; Stefania Saoncella; Fabienne Denhez; Michael Detmar; Paul F Goetinck
Delayed wound repair and impaired angiogenesis in mice lacking syndecan-4.
The Journal of clinical investigation 2001;107(2):R9-R14.
2000: Michael Detmar
Tumor angiogenesis.
The journal of investigative dermatology. Symposium proceedings / the Society for Investigative Dermatology, Inc. [and] European Society for Dermatological Research 2000;5(1):20-3.
2000: Mihaela Skobe; Michael Detmar
Structure, function, and molecular control of the skin lymphatic system.
The journal of investigative dermatology. Symposium proceedings / the Society for Investigative Dermatology, Inc. [and] European Society for Dermatological Research 2000;5(1):14-9.
2000: Michael Detmar
The role of VEGF and thrombospondins in skin angiogenesis.
Journal of dermatological science 2000;24 Suppl 1():S78-84.
2000: Michael Streit; Paula Velasco; Lucia Riccardi; L Spencer; Lawrence F Brown; Lauren Janes; Bernhard Lange-Asschenfeldt; Kiichiro Yano; Thomas Hawighorst; L Iruela-Arispe; Michael Detmar
Thrombospondin-1 suppresses wound healing and granulation tissue formation in the skin of transgenic mice.
The EMBO journal 2000;19(13):3272-82.
2000: Jiro Kishimoto; Ritsuko Ehama; Y Ge; T Kobayashi; T Nishiyama; Michael Detmar; Robert E Burgeson
In vivo detection of human vascular endothelial growth factor promoter activity in transgenic mouse skin.
The American journal of pathology 2000;157(1):103-10.
2000: Michael Detmar; Paula Velasco; L Richard; Kevin P Claffey; Michael Streit; Lucia Riccardi; Mihaela Skobe; Lawrence F Brown
Expression of vascular endothelial growth factor induces an invasive phenotype in human squamous cell carcinomas.
The American journal of pathology 2000;156(1):159-67.
1999: Michael Streit; Lucia Riccardi; Paula Velasco; Lawrence F Brown; Thomas Hawighorst; Paul Bornstein; Michael Detmar
Thrombospondin-2: a potent endogenous inhibitor of tumor growth and angiogenesis.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(26):14888-93.
1999: Mihaela Skobe; Lawrence F Brown; K Tognazzi; Ramesh K Ganju; Bruce J Dezube; Kari Alitalo; Michael Detmar
Vascular endothelial growth factor-C (VEGF-C) and its receptors KDR and flt-4 are expressed in AIDS-associated Kaposi's sarcoma.
The Journal of investigative dermatology 1999;113(6):1047-53.
1999: Michael Streit; Paula Velasco; Lawrence F Brown; Mihaela Skobe; L Richard; Lucia Riccardi; Jack Lawler; Michael Detmar
Overexpression of thrombospondin-1 decreases angiogenesis and inhibits the growth of human cutaneous squamous cell carcinomas.
The American journal of pathology 1999;155(2):441-52.
1999: S F Penc; Bohdan Pomahac; Elof Eriksson; Michael Detmar; Richard L Gallo
Dermatan sulfate activates nuclear factor-kappab and induces endothelial and circulating intercellular adhesion molecule-1.
The Journal of clinical investigation 1999;103(9):1329-35.
1999: L Richard; Paula Velasco; Michael Detmar
Isolation and culture of microvascular endothelial cells.
Methods in molecular medicine 1999;18():261-9.
1998: Michael Detmar; Lawrence F Brown; M P Schön; B M Elicker; Paula Velasco; L Richard; D Fukumura; Wayne L Monsky; Kevin P Claffey; R K Jain
Increased microvascular density and enhanced leukocyte rolling and adhesion in the skin of VEGF transgenic mice.
The Journal of investigative dermatology 1998;111(1):1-6.
1998: Lotta Jussila; R Valtola; Taina A Partanen; Petri Salven; Päivi Heikkilä; M T Matikainen; Risto Renkonen; A Kaipainen; Michael Detmar; E Tschachler; Riitta Alitalo; Kari Alitalo
Lymphatic endothelium and Kaposi's sarcoma spindle cells detected by antibodies against the vascular endothelial growth factor receptor-3.
Cancer research 1998;58(8):1599-604.
1998: L Richard; Paula Velasco; Michael Detmar
A simple immunomagnetic protocol for the selective isolation and long-term culture of human dermal microvascular endothelial cells.
Experimental cell research 1998;240(1):1-6.
1998: Kevin P Claffey; SC Shih; A Mullen; Suzan Dziennis; J L Cusick; K R Abrams; S W Lee; Michael Detmar
Identification of a human VPF/VEGF 3' untranslated region mediating hypoxia-induced mRNA stability.
Molecular biology of the cell 1998;9(2):469-81.
1997: Donald R Senger; Kevin P Claffey; J E Benes; Carole A Perruzzi; A P Sergiou; Michael Detmar
Angiogenesis promoted by vascular endothelial growth factor: regulation through alpha1beta1 and alpha2beta1 integrins.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(25):13612-7.
1997: Y Watanabe; S W Lee; Michael Detmar; I Ajioka; H F Dvorak
Vascular permeability factor/vascular endothelial growth factor (VPF/VEGF) delays and induces escape from senescence in human dermal microvascular endothelial cells.
Oncogene 1997;14(17):2025-32.
1997: A P Smyth; S L Rook; Michael Detmar; G S Robinson
Antisense oligonucleotides inhibit vascular endothelial growth factor/vascular permeability factor expression in normal human epidermal keratinocytes.
The Journal of investigative dermatology 1997;108(4):523-6.
1997: Michael Detmar; Lawrence F Brown; B Berse; Robert Jackman; B M Elicker; Harold F Dvorak; Kevin P Claffey
Hypoxia regulates the expression of vascular permeability factor/vascular endothelial growth factor (VPF/VEGF) and its receptors in human skin.
The Journal of investigative dermatology 1997;108(3):263-8.
1997: Lawrence F Brown; Michael Detmar; K Tognazzi; G Abu-Jawdeh; M Luisa Iruela-Arispe
Uterine smooth muscle cells express functional receptors (flt-1 and KDR) for vascular permeability factor/vascular endothelial growth factor.
Laboratory investigation; a journal of technical methods and pathology 1997;76(2):245-55.
1997: Michael P Schön; Michael Detmar; Christina M Parker
Murine psoriasis-like disorder induced by naive CD4+ T cells.
Nature medicine 1997;3(2):183-8.
1997: Lawrence F Brown; Michael Detmar; Kevin P Claffey; Janice A Nagy; D Feng; Ann M Dvorak; Harold F Dvorak
Vascular permeability factor/vascular endothelial growth factor: a multifunctional angiogenic cytokine.
EXS 1997;79():233-69.
1996: Regina Treudler; Christos Zouboulis; P Büttner; Michael Detmar; Constantin E Orfanos
Enhanced interaction of patients' lymphocytes with human dermal microvascular endothelial cell cultures in active Adamantiades-Behçet disease.
Archives of dermatology 1996;132(11):1323-9.
1996: D R Senger; S R Ledbetter; Kevin P Claffey; A Papadopoulos-Sergiou; C A Peruzzi; Michael Detmar
Stimulation of endothelial cell migration by vascular permeability factor/vascular endothelial growth factor through cooperative mechanisms involving the alphavbeta3 integrin, osteopontin, and thrombin.
The American journal of pathology 1996;149(1):293-305.
1996: Michael Detmar
Molecular regulation of angiogenesis in the skin.
The Journal of investigative dermatology 1996;106(2):207-8.
1995: Michael Detmar; K T Yeo; Janice A Nagy; Livingston Van De Water; Lawrence F Brown; Brygida Berse; B M Elicker; S Ledbetter; Harold F Dvorak
Keratinocyte-derived vascular permeability factor (vascular endothelial growth factor) is a potent mitogen for dermal microvascular endothelial cells.
The Journal of investigative dermatology 1995;105(1):44-50.
1995: Lawrence F Brown; T J Harrist; K T Yeo; M Ståhle-Bäckdahl; Robert Jackman; Brygida Berse; K Tognazzi; Harold F Dvorak; Michael Detmar
Increased expression of vascular permeability factor (vascular endothelial growth factor) in bullous pemphigoid, dermatitis herpetiformis, and erythema multiforme.
The Journal of investigative dermatology 1995;104(5):744-9.
1995: Harold F Dvorak; Michael Detmar; Kevin P Claffey; Janice A Nagy; Livingston Van De Water; D R Senger
Vascular permeability factor/vascular endothelial growth factor: an important mediator of angiogenesis in malignancy and inflammation.
International archives of allergy and immunology 1995;107(1-3):233-5.
1995: Harold F Dvorak; Lawrence F Brown; Michael Detmar; Ann M Dvorak
Vascular permeability factor/vascular endothelial growth factor, microvascular hyperpermeability, and angiogenesis.
The American journal of pathology 1995;146(5):1029-39.
1995: C Trautmann; M B Abdel-Naser; R Soehnchen; Michael Detmar; Constantin E Orfanos
[Pre-myopathic versus amyopathic dermatomyositis. 2 personal cases and review of the literature].
Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete 1995;46(1):47-52.
1995: C Trautmann; H G Hahnemann; E T Hilbert; Michael Detmar; H Gollnick; Constantin E Orfanos
[Large cell anaplastic Ki-1 positive lymphoma of the skin. 5 personal cases and review of the literature].
Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete 1995;46(1):28-34.
1994: Michael Detmar; Lawrence F Brown; Kevin P Claffey; K T Yeo; Olivier Kocher; Robert Jackman; Brygida Berse; Harold F Dvorak
Overexpression of vascular permeability factor/vascular endothelial growth factor and its receptors in psoriasis.
The Journal of experimental medicine 1994;180(3):1141-6.
1994: Michael Detmar; Christoph C Geilen; Thomas Wieder; Constantin E Orfanos; Werner Reutter
Phospholipid analogue hexadecylphosphocholine inhibits proliferation and phosphatidylcholine biosynthesis of human epidermal keratinocytes in vitro.
The Journal of investigative dermatology 1994;102(4):490-4.
1994: A Bauer; C Garbe; Michael Detmar; E D Kreuser; H Gollnick
[Multicentric reticulohistiocytosis and myelodysplastic syndrome].
Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete 1994;45(2):91-6.
1994: U Blume; M P Schön; Christos Zouboulis; Michael Detmar; Constantin E Orfanos
Vellus hair follicle-derived keratinocyte culture: a new experimental model in human hair research.
Skin pharmacology : the official journal of the Skin Pharmacology Society 1994;7(1-2):27-32.
1993: U Hettmannsperger; R Soehnchen; H Gollnick; Michael Detmar; Constantin E Orfanos
[Bacillary epithelioid angiomatosis in advanced HIV infection].
Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete 1993;44(12):803-7.
1993: Michael Detmar; F M Schaart; U Blume; Constantin E Orfanos
Culture of hair matrix and follicular keratinocytes.
The Journal of investigative dermatology 1993;101(1 Suppl):130S-134S.
1993: U Hettmannsperger; S Tenorio; Constantin E Orfanos; Michael Detmar
Corticosteroids induce proliferation but do not influence TNF- or IL-1 beta-induced ICAM-1 expression of human dermal microvascular endothelial cells in vitro.
Archives of dermatological research 1993;285(6):347-51.
1992: Michael Detmar
[Mechanism of the interaction of leukocytes and dermal endothelial cells in cutaneous inflammation].
Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete 1992;43(11):679-86.
1992: U Hettmannsperger; Michael Detmar; M Owsianowski; S Tenorio; H J Kammler; Constantin E Orfanos
Cytokine-stimulated human dermal microvascular endothelial cells produce interleukin 6--inhibition by hydrocortisone, dexamethasone, and calcitriol.
The Journal of investigative dermatology 1992;99(5):531-6.
1992: K Schröder; C Garbe; M Waibel; H Reupke; Michael Detmar; F Dallenbach; Constantin E Orfanos
[Granulocyte colony stimulating factor (G-CSF) in treatment of patients with HIV-associated mucocutaneous Kaposi sarcoma. Successful use in virus and drug-induced leukopenia].
Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete 1992;43(11):700-6.
1992: M Asada; F M Schaart; Michael Detmar; Dietmar Mischke; H L de Almeida; H Gollnick; Constantin E Orfanos
Growth characteristics and differentiation of basal cell carcinoma in vitro--immunohistochemical, gel electrophoretic, and ultrastructural analysis.
The Journal of investigative dermatology 1992;99(4):474-81.
1992: J Albig; H Gollnick; Michael Detmar; Constantin E Orfanos
[Linear hyperpigmentation caused by bleomycin].
Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete 1992;43(6):376-9.
1992: Michael Detmar; S Tenorio; U Hettmannsperger; Zbigniew Ruszczak; Constantin E Orfanos
Cytokine regulation of proliferation and ICAM-1 expression of human dermal microvascular endothelial cells in vitro.
The Journal of investigative dermatology 1992;98(2):147-53.
1991: Michael Detmar; G Pauli; Ioannis Anagnostopoulos; U Wunderlich; Hermann Herbst; Claus Garbe; Harald Stein; Constantin E Orfanos
A case of classical mycosis fungoides associated with human T-cell lymphotropic virus type I.
The British journal of dermatology 1991;124(2):198-202.
1991: E Imcke; Zbigniew Ruszczak; A Mayer-da Silva; Michael Detmar; Constantin E Orfanos
Cultivation of human dermal microvascular endothelial cells in vitro: immunocytochemical and ultrastructural characterization and effect of treatment with three synthetic retinoids.
Archives of dermatological research 1991;283(3):149-57.
1991: Christos Zouboulis; L Q Xia; Michael Detmar; B Bogdanoff; G Giannakopoulos; H Gollnick; Constantin E Orfanos
Culture of human sebocytes and markers of sebocytic differentiation in vitro.
Skin pharmacology : the official journal of the Skin Pharmacology Society 1991;4(2):74-83.
1990: E Imcke; Michael Detmar; Zbigniew Ruszczak; Constantin E Orfanos
[Preliminary findings on lectin binding in human follicular epithelium].
Zeitschrift für Hautkrankheiten 1990;65(12):1123-7.
1990: Michael Detmar; E Imcke; Zbigniew Ruszczak; Constantin E Orfanos
Effects of recombinant tumor necrosis factor-alpha on cultured microvascular endothelial cells derived from human dermis.
The Journal of investigative dermatology 1990;95(6 Suppl):219S-222S.
1990: Zbigniew Ruszczak; Michael Detmar; E Imcke; Constantin E Orfanos
Effects of rIFN alpha, beta, and gamma on the morphology, proliferation, and cell surface antigen expression of human dermal microvascular endothelial cells in vitro.
The Journal of investigative dermatology 1990;95(6):693-9.
1990: Michael Detmar; Zbigniew Ruszczak; E Imcke; R Stadler; Constantin E Orfanos
[Kyrle disease in juvenile diabetes mellitus and chronic renal failure].
Zeitschrift für Hautkrankheiten 1990;65(1):53-61.
1990: Michael Detmar; Constantin E Orfanos
Tumor necrosis factor-alpha inhibits cell proliferation and induces class II antigens and cell adhesion molecules in cultured normal human keratinocytes in vitro.
Archives of dermatological research 1990;282(4):238-45.
1990: Michael Detmar; A Mayer-da-Silva; R Stadler; Constantin E Orfanos
Initial hyperproliferation and incomplete terminal differentiation of cultured human keratinocytes from lesional and uninvolved psoriatic skin.
Acta dermato-venereologica 1990;70(4):295-9.
1989: R Stadler; Michael Detmar; K Stephanek; C Bangemann; Constantin E Orfanos
A rapid fluorometric assay for the determination of keratinocyte proliferation in vitro.
The Journal of investigative dermatology 1989;93(4):532-4.
1989: L Q Xia; Christos Zouboulis; Michael Detmar; A Mayer-da-Silva; R Stadler; Constantin E Orfanos
Isolation of human sebaceous glands and cultivation of sebaceous gland-derived cells as an in vitro model.
The Journal of investigative dermatology 1989;93(3):315-21.
1989: Michael Detmar; A Mayer-da-Silva; R Stadler; Constantin E Orfanos
Effects of azelaic acid on proliferation and ultrastructure of mouse keratinocytes in vitro.
The Journal of investigative dermatology 1989;93(1):70-4.
1989: A Mayer-da-Silva; H Gollnick; Michael Detmar; J Gassmüller; A Parry; R Müller; Constantin E Orfanos
Effects of azelaic acid on sebaceous gland, sebum excretion rate and keratinization pattern in human skin. An in vivo and in vitro study.
Acta dermato-venereologica. Supplementum 1989;143():20-30.
1988: M Kiessling; G Mies; W Paschen; R Thilmann; Michael Detmar; K A Hossmann
Blood flow and metabolism in heterotopic cerebellar grafts during hypoglycemia.
Acta neuropathologica 1988;77(2):142-51.
1987: E Imcke; A Mayer-da-Silva; Michael Detmar; H Tiel; R Stadler; Constantin E Orfanos
Growth of human hair follicle keratinocytes in vitro. Ultrastructural features of a new model.
Journal of the American Academy of Dermatology 1987;17(5 Pt 1):779-86.
1987: R Müller; E Naumann; Michael Detmar; C E Orfanos
[Stability of cignolin (dithranol) in ointments containing tar with and without the addition of salicylic acid. Oxidation to danthron and dithranol dimer].
Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete 1987;38(2):107-11.
1987: S Bien; Martin Schumacher; Michael Detmar
Nucleolysis and diskography--an experimental study on interaction of chymopapain and contrast medium.
Neuroradiology 1987;29(5):483-7.
1987: R Stadler; R Müller; Michael Detmar; Constantin E Orfanos
Retinoids and keratinocyte differentiation in vitro.
Dermatologica 1987;175 Suppl 1():45-55.
1986: Michael Detmar; R Müller; R Stadler; C E Orfanos
[Dicarboxylic acids inhibit the growth of keratinocytes in vitro].
Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete 1986;37(11):625-7.
1986: B Volk; N Kirchgässner; Michael Detmar
Degeneration of granule cells following chronic phenytoin administration: an electron microscopic investigation of the mouse cerebellum.
Experimental neurology 1986;91(1):60-70.