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Dale Deutsch

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Martin Kaczocha; Qingqing Lin; Erwin London; Michelle K McKinney; Lindsay D Nelson; Benjamin F Cravatt; Dale G Deutsch
Anandamide externally added to lipid vesicles containing-trapped fatty acid amide hydrolase (FAAH) is readily hydrolyzed in a sterol-modulated fashion.
Martin Kaczocha; Jing Sun; Stephanie Vivieca; Sherrye T Glaser; Dale G Deutsch
Fatty acid-binding proteins transport N-acylethanolamines to nuclear receptors and are targets of endocannabinoid transport inhibitors.
William T Berger; Trent E Balius; Samir Haj-Dahmane; Martin Kaczocha; Iwao Ojima; Brian P Ralph; Robert C Rizzo; Jing Sun; Dale G Deutsch
Targeting fatty acid binding protein (FABP) anandamide transporters - a novel strategy for development of anti-inflammatory and anti-nociceptive drugs.

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All Publications

2012: Martin Kaczocha; Qingqing Lin; Erwin London; Michelle K McKinney; Lindsay D Nelson; Benjamin F Cravatt; Dale G Deutsch
Anandamide externally added to lipid vesicles containing-trapped fatty acid amide hydrolase (FAAH) is readily hydrolyzed in a sterol-modulated fashion.
ACS chemical neuroscience 2012;3(5):364-8.
2012: Martin Kaczocha; Jing Sun; Stephanie Vivieca; Sherrye T Glaser; Dale G Deutsch
Fatty acid-binding proteins transport N-acylethanolamines to nuclear receptors and are targets of endocannabinoid transport inhibitors.
The Journal of biological chemistry 2012;287(5):3415-24.
2012: William T Berger; Trent E Balius; Samir Haj-Dahmane; Martin Kaczocha; Iwao Ojima; Brian P Ralph; Robert C Rizzo; Jing Sun; Dale G Deutsch
Targeting fatty acid binding protein (FABP) anandamide transporters - a novel strategy for development of anti-inflammatory and anti-nociceptive drugs.
PloS one 2012;7(12):e50968.
2011: Allyn C Howlett; Patricia H Reggio; Nadine M Ulloa; Steven R Childers; Robert E Hampson; Dale G Deutsch
Endocannabinoid tone versus constitutive activity of cannabinoid receptors.
British journal of pharmacology 2011;163(7):1329-43.
2010: Nadine M Ulloa; Dale G Deutsch
Assessment of a spectrophotometric assay for monoacylglycerol lipase activity.
The AAPS journal 2010;12(2):197-201.
2010: Martin Kaczocha; Sherrye T Glaser; Janiper Chae; Deborah A Brown; Dale G Deutsch
Lipid droplets are novel sites of N-acylethanolamine inactivation by fatty acid amide hydrolase-2.
The Journal of biological chemistry 2010;285(4):2796-806.
2009: Martin Kaczocha; Sherrye T Glaser; Dale G Deutsch
Identification of intracellular carriers for the endocannabinoid anandamide.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(15):6375-80.
2006: Martin Kaczocha; Anita Hermann; Sherrye T Glaser; Inge N Bojesen; Dale G Deutsch
Anandamide uptake is consistent with rate-limited diffusion and is regulated by the degree of its hydrolysis by fatty acid amide hydrolase.
The Journal of biological chemistry 2006;281(14):9066-75.
2006: Anita Hermann; Martin Kaczocha; Dale G Deutsch
2-Arachidonoylglycerol (2-AG) membrane transport: history and outlook.
The AAPS journal 2006;8(2):E409-12.
2005: Sherrye T Glaser; Dale G Deutsch; Keith M Studholme; Sarah Zimov; Stephen Yazulla
Endocannabinoids in the intact retina: 3 H-anandamide uptake, fatty acid amide hydrolase immunoreactivity and hydrolysis of anandamide.
Visual neuroscience 2005;22(6):693-705.
2005: Dale G Deutsch
Design of on-target FAAH inhibitors.
Chemistry & biology 2005;12(11):1157-8.
2005: Sherrye T Glaser; Martin Kaczocha; Dale G Deutsch
Anandamide transport: a critical review.
Life sciences 2005;77(14):1584-604.
2003: Sherrye T Glaser; Nada A Abumrad; Folayan Fatade; Martin Kaczocha; Keith M Studholme; Dale G Deutsch
Evidence against the presence of an anandamide transporter.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(7):4269-74.
2002: Dale G Deutsch; N Ueda; S Yamamoto
The fatty acid amide hydrolase (FAAH).
Prostaglandins, leukotrienes, and essential fatty acids 2002;66(2-3):201-10.
2001: RA Puffenbarger; O Kapulina; J M Howell; Dale G Deutsch
Characterization of the 5'-sequence of the mouse fatty acid amide hydrolase.
Neuroscience letters 2001;314(1-2):21-4.
2001: Dale G Deutsch; Sherrye T Glaser; J M Howell; J S Kunz; RA Puffenbarger; C J Hillard; Nada A Abumrad
The cellular uptake of anandamide is coupled to its breakdown by fatty-acid amide hydrolase.
The Journal of biological chemistry 2001;276(10):6967-73.
2000: Nobuhiko Ueda; RA Puffenbarger; Shigeru Yamamoto; Dale G Deutsch
The fatty acid amide hydrolase (FAAH).
Chemistry and physics of lipids 2000;108(1-2):107-21.
1999: Stephen Yazulla; Keith M Studholme; H H McIntosh; Dale G Deutsch
Immunocytochemical localization of cannabinoid CB1 receptor and fatty acid amide hydrolase in rat retina.
The Journal of comparative neurology 1999;415(1):80-90.
1999: RL Omeir; G Arreaza; Dale G Deutsch
Identification of two serine residues involved in catalysis by fatty acid amide hydrolase.
Biochemical and biophysical research communications 1999;264(2):316-20.
1999: G Arreaza; Dale G Deutsch
Deletion of a proline-rich region and a transmembrane domain in fatty acid amide hydrolase.
FEBS letters 1999;454(1-2):57-60.
1997: G Arreaza; W A Devane; RL Omeir; G Sajnani; J Kunz; B F Cravatt; Dale G Deutsch
The cloned rat hydrolytic enzyme responsible for the breakdown of anandamide also catalyzes its formation via the condensation of arachidonic acid and ethanolamine.
Neuroscience letters 1997;234(1):59-62.
1997: Dale G Deutsch; M S Goligorsky; Patricia C Schmid; Randy J Krebsbach; Harald H O Schmid; S K Das; Sudhansu K Dey; G Arreaza; C Thorup; G Stefano; Leon C Moore
Production and physiological actions of anandamide in the vasculature of the rat kidney.
The Journal of clinical investigation 1997;100(6):1538-46.
1997: Dale G Deutsch; RL Omeir; G Arreaza; D Salehani; Glenn D Prestwich; Z Huang; A Howlett
Methyl arachidonyl fluorophosphonate: a potent irreversible inhibitor of anandamide amidase.
Biochemical pharmacology 1997;53(3):255-60.
1997: Dale G Deutsch; S Lin; W A Hill; K L Morse; D Salehani; G Arreaza; RL Omeir; A Makriyannis
Fatty acid sulfonyl fluorides inhibit anandamide metabolism and bind to the cannabinoid receptor.
Biochemical and biophysical research communications 1997;231(1):217-21.
1997: Dale G Deutsch; A Makriyannis
Inhibitors of anandamide breakdown.
NIDA research monograph 1997;173():65-84.
1995: RL Omeir; S Chin; Y Hong; D G Ahern; Dale G Deutsch
Arachidonoyl ethanolamide-[1,2-14C] as a substrate for anandamide amidase.
Life sciences 1995;56(23-24):1999-2005.
1994: B Koutek; Glenn D Prestwich; A C Howlett; S A Chin; D Salehani; N Akhavan; Dale G Deutsch
Inhibitors of arachidonoyl ethanolamide hydrolysis.
The Journal of biological chemistry 1994;269(37):22937-40.
1993: Eugene Tombler; Dale G Deutsch
Spectrofluorometric assay for hybridization of oligodeoxynucleotides using ethidium dimer.
BioTechniques 1993;15(6):1060-4.
1993: Dale G Deutsch; S A Chin
Enzymatic synthesis and degradation of anandamide, a cannabinoid receptor agonist.
Biochemical pharmacology 1993;46(5):791-6.
1991: Dale G Deutsch; Eugene Tombler; J E March; S H Lo; M Adesnik
Potentiation of the inductive effect of phenobarbital on cytochrome P450 mRNAs by cannabidiol.
Biochemical pharmacology 1991;42(10):2048-53.
1988: I Fand; W P McNally; O Koul; Y Yonekura; P Som; A B Brill; Dale G Deutsch
Whole-body autoradiographic localization of [3H]phencyclidine and its metabolites in mice.
Toxicology and applied pharmacology 1988;93(3):421-32.
1986: O Koul; J E March; R Sarma; C Griffiths; Dale G Deutsch
Effect of phencyclidine on the metabolism of individual brain proteins.
Journal of neurochemistry 1986;46(2):470-4.
1984: Dale G Deutsch; O Koul; R S Kersten
Phencyclidine and analogues: effects on brain protein synthesis.
Journal of neurochemistry 1984;42(2):407-11.