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Josef Deutscher

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A Bourand; Alain Mazé; M J Yebra; Grégory Boël; Josef Deutscher
Utilization of D-Ribitol by Lactobacillus casei BL23 Requires a Mannose-Type Phosphotransferase System and Three Catabolic Enzymes.
Nicolas Sauvageot; Abdellah Benachour; Josef Deutscher; Rabia Ladjouzi; Rince Alain; Axel Hartke
Aerobic glycerol dissimilation via the Enterococcus faecalis DhaK pathway depends on NADH oxidase and a phosphotransfer reaction from PEP to DhaK via EIIADha.
Céline Monniot; Arthur Constant Zébré; Francine Moussan Désirée Aké; Josef Deutscher; Eliane Milohanic
Novel listerial glycerol dehydrogenase- and phosphoenolpyruvate-dependent dihydroxyacetone kinase system connected to the pentose phosphate pathway.

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2013: A Bourand; Alain Mazé; M J Yebra; Grégory Boël; Josef Deutscher
Utilization of D-Ribitol by Lactobacillus casei BL23 Requires a Mannose-Type Phosphotransferase System and Three Catabolic Enzymes.
Journal of bacteriology 2013;195(11):2652-61.
2012: Nicolas Sauvageot; Abdellah Benachour; Josef Deutscher; Rabia Ladjouzi; Rince Alain; Axel Hartke
Aerobic glycerol dissimilation via the Enterococcus faecalis DhaK pathway depends on NADH oxidase and a phosphotransfer reaction from PEP to DhaK via EIIADha.
Microbiology (Reading, England) 2012;158(Pt 10):2661-6.
2012: Céline Monniot; Arthur Constant Zébré; Francine Moussan Désirée Aké; Josef Deutscher; Eliane Milohanic
Novel listerial glycerol dehydrogenase- and phosphoenolpyruvate-dependent dihydroxyacetone kinase system connected to the pentose phosphate pathway.
Journal of bacteriology 2012;194(18):4972-82.
2011: Stéphane Perchat; Sandrine Poncet; Samira Zouhir; Sylvie Nessler; Magali Aumont-Nicaise; Josef Deutscher; Thomas Dubois; Michel Gohar; Myriam Gominet; Christelle Lemy; Didier Lereclus
A cell-cell communication system regulates protease production during sporulation in bacteria of the Bacillus cereus group.
Molecular microbiology 2011;82(3):619-33.
2011: Sandeep K Misra; Véronique Monnet; Francine Aké; Josef Deutscher; Ivan Mijakovic; Eliane Milohanic; Céline Henry
Analysis of the serine/threonine/tyrosine phosphoproteome of the pathogenic bacterium Listeria monocytogenes reveals phosphorylated proteins related to virulence.
Proteomics 2011;11(21):4155-65.
2011: Francine M D Aké; Josef Deutscher; Philippe Joyet; Eliane Milohanic
Mutational analysis of glucose transport regulation and glucose-mediated virulence gene repression in Listeria monocytogenes.
Molecular microbiology 2011;81(1):274-93.
2010: Philippe Joyet; Meriem Derkaoui; Sandrine Poncet; Josef Deutscher
Control of Bacillus subtilis mtl operon expression by complex phosphorylation-dependent regulation of the transcriptional activator MtlR.
Molecular microbiology 2010;76(5):1279-94.
2010: Alain Mazé; Grégory Boël; Manuel Zúñiga; Alexa Bourand; Valentin Loux; Maria Jesus Yebra; Vicente Monedero; Karine Correia; Noémie Jacques; Sophie Beaufils; Sandrine Poncet; Philippe Joyet; Eliane Milohanic; Serge Casarégola; Yanick Auffray; Gaspar Pérez-Martínez; Jean-François Gibrat; Monique Zagorec; Christof Francke; Axel Hartke; Josef Deutscher
Complete genome sequence of the probiotic Lactobacillus casei strain BL23.
Journal of bacteriology 2010;192(10):2647-8.
2010: Marie Dozot; Sandrine Poncet; Cécile Nicolas; Richard Copin; Houda Bouraoui; Alain Mazé; Josef Deutscher; Xavier De Bolle; Jean-Jacques LETESSON
Functional characterization of the incomplete phosphotransferase system (PTS) of the intracellular pathogen Brucella melitensis.
PloS one 2010;5(9):.
2009: Sandrine Poncet; Maryline Soret; Peggy Mervelet; Josef Deutscher; Philippe Noirot
Transcriptional activator YesS is stimulated by histidine-phosphorylated HPr of the Bacillus subtilis phosphotransferase system.
The Journal of biological chemistry 2009;284(41):28188-97.
2009: Joanne I Yeh; Regina Kettering; Ruth Saxl; Alexa Bourand; Emmanuelle Darbon; Nathalie Joly; Pierre Briozzo; Josef Deutscher
Structural characterizations of glycerol kinase: unraveling phosphorylation-induced long-range activation.
Biochemistry 2009;48(2):346-56.
2009: Sandrine Poncet; Eliane Milohanic; Alain Mazé; Jamila Nait Abdallah; Francine Aké; Mireille Larribe; Ala-Eddine Deghmane; Muhamed-Kheir Taha; Marie Dozot; Xavier De Bolle; Jean-Jacques LETESSON; Josef Deutscher
Correlations between carbon metabolism and virulence in bacteria.
Contributions to microbiology 2009;16():88-102.
2009: Dina Petranovic; Christophe Grangeasse; Boris Macek; Mohammad Abdillatef; Virginie Gueguen-Chaignon; Sylvie Nessler; Josef Deutscher; Ivan Mijakovic
Activation of Bacillus subtilis Ugd by the BY-kinase PtkA proceeds via phosphorylation of its residue tyrosine 70.
Journal of molecular microbiology and biotechnology 2009;17(2):83-9.
2008: Cristina Alcántara; Luz Adriana Sarmiento-Rubiano; Vicente Monedero; Josef Deutscher; Gaspar Pérez-Martínez; María Jesús Yebra
Regulation of Lactobacillus casei sorbitol utilization genes requires DNA-binding transcriptional activator GutR and the conserved protein GutM.
Applied and environmental microbiology 2008;74(18):5731-40.
2008: Carsten Jers; Boumediene Soufi; Christophe Grangeasse; Josef Deutscher; Ivan Mijakovic
Phosphoproteomics in bacteria: towards a systemic understanding of bacterial phosphorylation networks.
Expert review of proteomics 2008;5(4):619-27.
2008: Vanesa Olivares-Illana; Philippe Meyer; Emmanuelle Bechet; Virginie Gueguen-Chaignon; Didier Soulat; Sylvie Lazereg-Riquier; Ivan Mijakovic; Josef Deutscher; Alain J Cozzone; Olivier Laprévote; Solange Morera; Christophe Grangeasse; Sylvie Nessler
Structural basis for the regulation mechanism of the tyrosine kinase CapB from Staphylococcus aureus.
PLoS biology 2008;6(6):e143.
2008: Juan Rico; María Jesús Yebra; Gaspar Pérez-Martínez; Josef Deutscher; Vicente Monedero
Analysis of ldh genes in Lactobacillus casei BL23: role on lactic acid production.
Journal of industrial microbiology & biotechnology 2008;35(6):579-86.
2008: Vicente Monedero; María Jesús Yebra; Sandrine Poncet; Josef Deutscher
Maltose transport in Lactobacillus casei and its regulation by inducer exclusion.
Research in microbiology 2008;159(2):94-102.
2007: Vincent Chaptal; Fanny Vincent; Virginie Gueguen-Chaignon; Vicente Monedero; Sandrine Poncet; Josef Deutscher; Sylvie Nessler; Solange Morera
Structural analysis of the bacterial HPr kinase/phosphorylase V267F mutant gives insights into the allosteric regulation mechanism of this bifunctional enzyme.
The Journal of biological chemistry 2007;282(48):34952-7.
2007: María Jesús Yebra; Manuel Zúñiga; Sophie Beaufils; Gaspar Pérez-Martínez; Josef Deutscher; Vicente Monedero
Identification of a gene cluster enabling Lactobacillus casei BL23 to utilize myo-inositol.
Applied and environmental microbiology 2007;73(12):3850-8.
2007: Christophe Grangeasse; Alain J Cozzone; Josef Deutscher; Ivan Mijakovic
Tyrosine phosphorylation: an emerging regulatory device of bacterial physiology.
Trends in biochemical sciences 2007;32(2):86-94.
2007: Sophie Beaufils; Nicolas Sauvageot; Alain Mazé; Jean-Marie Laplace; Yanick Auffray; Josef Deutscher; Axel Hartke
The cold shock response of Lactobacillus casei: relation between HPr phosphorylation and resistance to freeze/thaw cycles.
Journal of molecular microbiology and biotechnology 2007;13(1-3):65-75.
2007: Vicente Monedero; Alain Mazé; Grégory Boël; Manuel Zúñiga; Sophie Beaufils; Axel Hartke; Josef Deutscher
The phosphotransferase system of Lactobacillus casei: regulation of carbon metabolism and connection to cold shock response.
Journal of molecular microbiology and biotechnology 2007;12(1-2):20-32.
2007: Alain Mazé; Mary O'Connell-Motherway; Gerald F Fitzgerald; Josef Deutscher; Douwe van Sinderen
Identification and characterization of a fructose phosphotransferase system in Bifidobacterium breve UCC2003.
Applied and environmental microbiology 2007;73(2):545-53.
2006: Vincent Chaptal; Virginie Gueguen-Chaignon; Sandrine Poncet; Cécile Lecampion; Philippe Meyer; Josef Deutscher; Anne Galinier; Sylvie Nessler; Solange Moréra
Structural analysis of B. subtilis CcpA effector binding site.
Proteins 2006;64(3):814-6.
2006: Nicolas Sauvageot; Sophie Beaufils; Alain Mazé; Josef Deutscher; Axel Hartke
Cloning and characterization of a gene encoding a cold-shock protein in Lactobacillus casei.
FEMS microbiology letters 2006;254(1):55-62.
2006: María Jesús Yebra; Vicente Monedero; Manuel Zúñiga; Josef Deutscher; Gaspar Pérez-Martínez
Molecular analysis of the glucose-specific phosphoenolpyruvate : sugar phosphotransferase system from Lactobacillus casei and its links with the control of sugar metabolism.
Microbiology (Reading, England) 2006;152(Pt 1):95-104.
2005: Josef Deutscher; Rana Herro; Alexa Bourand; Ivan Mijakovic; Sandrine Poncet
P-Ser-HPr--a link between carbon metabolism and the virulence of some pathogenic bacteria.
Biochimica et biophysica acta 2005;1754(1-2):118-25.
2005: Rosa Viana; Gaspar Pérez-Martínez; Josef Deutscher; Vicente Monedero
The glycolytic genes pfk and pyk from Lactobacillus casei are induced by sugars transported by the phosphoenolpyruvate:sugar phosphotransferase system and repressed by CcpA.
Archives of microbiology 2005;183(6):385-93.
2005: Manuel Zúñiga; Iñaki Comas; Raquel Linaje; Vicente Monedero; María Jesús Yebra; Carlos Esteban; Josef Deutscher; Gaspar Pérez-Martínez; Fernando González-Candelas
Horizontal gene transfer in the molecular evolution of mannose PTS transporters.
Molecular biology and evolution 2005;22(8):1673-85.
2005: Ivan Mijakovic; Lucia Musumeci; Lutz Tautz; Dina Petranovic; Robert A Edwards; Peter R Jensen; Tomas Mustelin; Josef Deutscher; Nunzio Bottini
In vitro characterization of the Bacillus subtilis protein tyrosine phosphatase YwqE.
Journal of bacteriology 2005;187(10):3384-90.
2005: Rana Herro; Sandrine Poncet; Pascale Cossart; Carmen Buchrieser; Edith Gouin; Philippe Glaser; Josef Deutscher
How seryl-phosphorylated HPr inhibits PrfA, a transcription activator of Listeria monocytogenes virulence genes.
Journal of molecular microbiology and biotechnology 2005;9(3-4):224-34.
2005: Ivan Mijakovic; Dina Petranovic; Nunzio Bottini; Josef Deutscher; Peter Ruhdal Jensen
Protein-tyrosine phosphorylation in Bacillus subtilis.
Journal of molecular microbiology and biotechnology 2005;9(3-4):189-97.
2005: Josef Deutscher; Milton H Saier
Ser/Thr/Tyr protein phosphorylation in bacteria - for long time neglected, now well established.
Journal of molecular microbiology and biotechnology 2005;9(3-4):125-31.
2004: Alain Mazé; Grégory Boël; Sandrine Poncet; Ivan Mijakovic; Yoann Le Breton; Abdellah Benachour; Vicente Monedero; Josef Deutscher; Axel Hartke
The Lactobacillus casei ptsHI47T mutation causes overexpression of a LevR-regulated but RpoN-independent operon encoding a mannose class phosphotransferase system.
Journal of bacteriology 2004;186(14):4543-55.
2004: Grégory Boël; Vianney Pichereau; Ivan Mijakovic; Alain Mazé; Sandrine Poncet; Sylvie Gillet; Jean-Christophe Giard; Axel Hartke; Yanick Auffray; Josef Deutscher
Is 2-phosphoglycerate-dependent automodification of bacterial enolases implicated in their export?
Journal of molecular biology 2004;337(2):485-96.
2004: Sandrine Poncet; Ivan Mijakovic; Sylvie Nessler; Virginie Gueguen-Chaignon; Vincent Chaptal; Anne Galinier; Grégory Boël; Alain Mazé; Josef Deutscher
HPr kinase/phosphorylase, a Walker motif A-containing bifunctional sensor enzyme controlling catabolite repression in Gram-positive bacteria.
Biochimica et biophysica acta 2004;1697(1-2):123-35.
2004: Joanne I Yeh; Véronique Charrier; Joao Paulo; Lihui Hou; Emmanuelle Darbon; Al Claiborne; Wim G J Hol; Josef Deutscher
Structures of enterococcal glycerol kinase in the absence and presence of glycerol: correlation of conformation to substrate binding and a mechanism of activation by phosphorylation.
Biochemistry 2004;43(2):362-73.
2004: María Jesús Yebra; Rosa Viana; Vicente Monedero; Josef Deutscher; Gaspar Pérez-Martínez
An esterase gene from Lactobacillus casei cotranscribed with genes encoding a phosphoenolpyruvate:sugar phosphotransferase system and regulated by a LevR-like activator and sigma54 factor.
Journal of molecular microbiology and biotechnology 2004;8(2):117-28.
2004: Ivan Mijakovic; Dina Petranovic; Josef Deutscher
How tyrosine phosphorylation affects the UDP-glucose dehydrogenase activity of Bacillus subtilis YwqF.
Journal of molecular microbiology and biotechnology 2004;8(1):19-25.
2003: Christophe Grangeasse; Brice Obadia; Ivan Mijakovic; Josef Deutscher; Alain J Cozzone; Patricia Doublet
Autophosphorylation of the Escherichia coli protein kinase Wzc regulates tyrosine phosphorylation of Ugd, a UDP-glucose dehydrogenase.
The Journal of biological chemistry 2003;278(41):39323-9.
2003: Michel Juy; François Penin; Adrien Favier; Anne Galinier; Roland Montserret; Richard Haser; Josef Deutscher; Anja Böckmann
Dimerization of Crh by reversible 3D domain swapping induces structural adjustments to its monomeric homologue Hpr.
Journal of molecular biology 2003;332(4):767-76.
2003: Ivan Mijakovic; Sandrine Poncet; Grégory Boël; Alain Mazé; Sylvie Gillet; Emmanuel Jamet; Paulette Decottignies; Christophe Grangeasse; Patricia Doublet; Pierre Le Maréchal; Josef Deutscher
Transmembrane modulator-dependent bacterial tyrosine kinase activates UDP-glucose dehydrogenases.
The EMBO journal 2003;22(18):4709-18.
2003: Sylvie Nessler; Sonia Fieulaine; Sandrine Poncet; Anne Galinier; Josef Deutscher; Joël Janin
HPr kinase/phosphorylase, the sensor enzyme of catabolite repression in Gram-positive bacteria: structural aspects of the enzyme and the complex with its protein substrate.
Journal of bacteriology 2003;185(14):4003-10.
2003: Grégory Boël; Ivan Mijakovic; Alain Mazé; Sandrine Poncet; Muhamed-Kheir Taha; Mireille Larribe; Emmanuelle Darbon; Arbia Khemiri; Anne Galinier; Josef Deutscher
Transcription regulators potentially controlled by HPr kinase/phosphorylase in Gram-negative bacteria.
Journal of molecular microbiology and biotechnology 2003;5(4):206-15.
2002: Ivan Mijakovic; Sandrine Poncet; Anne Galinier; Vicente Monedero; Sonia Fieulaine; Joël Janin; Sylvie Nessler; José Antonio Marquez; Klaus Scheffzek; Sonja Hasenbein; Wolfgang Hengstenberg; Josef Deutscher
Pyrophosphate-producing protein dephosphorylation by HPr kinase/phosphorylase: a relic of early life?
Proceedings of the National Academy of Sciences of the United States of America 2002;99(21):13442-7.
2002: Sonia Fieulaine; Solange Morera; Sandrine Poncet; Ivan Mijakovic; Anne Galinier; Joël Janin; Josef Deutscher; Sylvie Nessler
X-ray structure of a bifunctional protein kinase in complex with its protein substrate HPr.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(21):13437-41.
2002: Cordula Lindner; Michael Hecker; Dominique Le Coq; Josef Deutscher
Bacillus subtilis mutant LicT antiterminators exhibiting enzyme I- and HPr-independent antitermination affect catabolite repression of the bglPH operon.
Journal of bacteriology 2002;184(17):4819-28.
2002: Adrien Favier; Bernhard Brutscher; Martin Blackledge; Anne Galinier; Josef Deutscher; François Penin; Dominique Marion
Solution structure and dynamics of Crh, the Bacillus subtilis catabolite repression HPr.
Journal of molecular biology 2002;317(1):131-44.
2002: Emmanuelle Darbon; Pascale Servant; Sandrine Poncet; Josef Deutscher
Antitermination by GlpP, catabolite repression via CcpA and inducer exclusion triggered by P-GlpK dephosphorylation control Bacillus subtilis glpFK expression.
Molecular microbiology 2002;43(4):1039-52.
2001: Pablo Tortosa; Nathalie Declerck; H Dutartre; Cordula Lindner; Josef Deutscher; Dominique Le Coq
Sites of positive and negative regulation in the Bacillus subtilis antiterminators LicT and SacY.
Molecular microbiology 2001;41(6):1381-93.
2001: Vicente Monedero; Sandrine Poncet; Ivan Mijakovic; Sonia Fieulaine; V Dossonnet; Isabelle Martin-Verstraete; Sylvie Nessler; Josef Deutscher
Mutations lowering the phosphatase activity of HPr kinase/phosphatase switch off carbon metabolism.
The EMBO journal 2001;20(15):3928-37.
2001: Sonia Fieulaine; Solange Morera; Sandrine Poncet; Vicente Monedero; Virginie Gueguen-Chaignon; Anne Galinier; Joël Janin; Josef Deutscher; Sylvie Nessler
X-ray structure of HPr kinase: a bacterial protein kinase with a P-loop nucleotide-binding domain.
The EMBO journal 2001;20(15):3917-27.
2001: Emmanuelle Darbon; Anne Galinier; Dominique Le Coq; Josef Deutscher
Phosphotransfer functions mutated Bacillus subtilis HPr-like protein Crh carrying a histidine in the active site.
Journal of molecular microbiology and biotechnology 2001;3(3):439-44.
2001: Vicente Monedero; Grégory Boël; Josef Deutscher
Catabolite regulation of the cytochrome c550-encoding Bacillus subtilis cccA gene.
Journal of molecular microbiology and biotechnology 2001;3(3):433-8.
2001: François Penin; A Favier; Roland Montserret; Bernhard Brutscher; Josef Deutscher; D Marion; D Galinier
Evidence for a dimerisation state of the Bacillus subtilis catabolite repression HPr-like protein, Crh.
Journal of molecular microbiology and biotechnology 2001;3(3):429-32.
2001: Vicente Monedero; O P Kuipers; E Jamet; Josef Deutscher
Regulatory functions of serine-46-phosphorylated HPr in Lactococcus lactis.
Journal of bacteriology 2001;183(11):3391-8.
2001: Sharik R Khan; Josef Deutscher; Ram A Vishwakarma; Vicente Monedero; N B Bhatnagar
The ptsH gene from Bacillus thuringiensis israelensis. Characterization of a new phosphorylation site on the protein HPr.
European journal of biochemistry / FEBS 2001;268(3):521-30.
2000: Gerald F Audette; Roswitha Engelmann; Wolfgang Hengstenberg; Josef Deutscher; K Hayakawa; J Wilson Quail; Louis T J Delbaere
The 1.9 A resolution structure of phospho-serine 46 HPr from Enterococcus faecalis.
Journal of molecular biology 2000;303(4):545-53.
2000: Rosa Viana; Vicente Monedero; V Dossonnet; C Vadeboncoeur; Gaspar Pérez-Martínez; Josef Deutscher
Enzyme I and HPr from Lactobacillus casei: their role in sugar transport, carbon catabolite repression and inducer exclusion.
Molecular microbiology 2000;36(3):570-84.
2000: V Dossonnet; Vicente Monedero; Monique Zagorec; Anne Galinier; Gaspar Pérez-Martínez; Josef Deutscher
Phosphorylation of HPr by the bifunctional HPr Kinase/P-ser-HPr phosphatase from Lactobacillus casei controls catabolite repression and inducer exclusion but not inducer expulsion.
Journal of bacteriology 2000;182(9):2582-90.
2000: Jean-Michel Jault; Sonia Fieulaine; Sylvie Nessler; Philippe Gonzalo; Attilio Di Pietro; Josef Deutscher; Anne Galinier
The HPr kinase from Bacillus subtilis is a homo-oligomeric enzyme which exhibits strong positive cooperativity for nucleotide and fructose 1,6-bisphosphate binding.
The Journal of biological chemistry 2000;275(3):1773-80.
1999: Emmanuelle Darbon; K Ito; H S Huang; T Yoshimoto; Sandrine Poncet; Josef Deutscher
Glycerol transport and phosphoenolpyruvate-dependent enzyme I- and HPr-catalysed phosphorylation of glycerol kinase in Thermus flavus.
Microbiology (Reading, England) 1999;145 ( Pt 11)():3205-12.
1999: Isabelle Martin-Verstraete; Anne Galinier; Emmanuelle Darbon; Y Quentin; Marie-Claude Kilhoffer; Véronique Charrier; jacques haiech; Georges Rapoport; Josef Deutscher
The Q15H mutation enables Crh, a Bacillus subtilis HPr-like protein, to carry out some regulatory HPr functions, but does not make it an effective phosphocarrier for sugar transport.
Microbiology (Reading, England) 1999;145 ( Pt 11)():3195-204.
1999: E Presecan-Siedel; Anne Galinier; R Longin; Josef Deutscher; Antoine Danchin; Philippe Glaser; Isabelle Martin-Verstraete
Catabolite regulation of the pta gene as part of carbon flow pathways in Bacillus subtilis.
Journal of bacteriology 1999;181(22):6889-97.
1999: Isabelle Martin-Verstraete; Josef Deutscher; Anne Galinier
Phosphorylation of HPr and Crh by HprK, early steps in the catabolite repression signalling pathway for the Bacillus subtilis levanase operon.
Journal of bacteriology 1999;181(9):2966-9.
1999: Anne Galinier; Josef Deutscher; Isabelle Martin-Verstraete
Phosphorylation of either crh or HPr mediates binding of CcpA to the bacillus subtilis xyn cre and catabolite repression of the xyn operon.
Journal of molecular biology 1999;286(2):307-14.
1999: Cordula Lindner; Anne Galinier; M Hecker; Josef Deutscher
Regulation of the activity of the Bacillus subtilis antiterminator LicT by multiple PEP-dependent, enzyme I- and HPr-catalysed phosphorylation.
Molecular microbiology 1999;31(3):995-1006.
1999: M Kravanja; Roswitha Engelmann; V Dossonnet; Martin Blüggel; Helmut E Meyer; R Frank; Anne Galinier; Josef Deutscher; N Schnell; Wolfgang Hengstenberg
The hprK gene of Enterococcus faecalis encodes a novel bifunctional enzyme: the HPr kinase/phosphatase.
Molecular microbiology 1999;31(1):59-66.
1998: Isabelle Martin-Verstraete; Véronique Charrier; Jörg Stülke; Anne Galinier; B Erni; Georges Rapoport; Josef Deutscher
Antagonistic effects of dual PTS-catalysed phosphorylation on the Bacillus subtilis transcriptional activator LevR.
Molecular microbiology 1998;28(2):293-303.
1998: Anne Galinier; M Kravanja; Roswitha Engelmann; Wolfgang Hengstenberg; Marie-Claude Kilhoffer; Josef Deutscher; jacques haiech
New protein kinase and protein phosphatase families mediate signal transduction in bacterial catabolite repression.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(4):1823-8.
1997: BE Jones; V Dossonnet; E Küster; Wolfgang Hillen; Josef Deutscher; Rachel E Klevit
Binding of the catabolite repressor protein CcpA to its DNA target is regulated by phosphorylation of its corepressor HPr.
The Journal of biological chemistry 1997;272(42):26530-5.
1997: Anne Galinier; jacques haiech; Marie-Claude Kilhoffer; Michel Jaquinod; Jörg Stülke; Josef Deutscher; Isabelle Martin-Verstraete
The Bacillus subtilis crh gene encodes a HPr-like protein involved in carbon catabolite repression.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(16):8439-44.
1997: Véronique Charrier; E Buckley; Derek Parsonage; Anne Galinier; Emmanuelle Darbon; Michel Jaquinod; Eric Forest; Josef Deutscher; Al Claiborne
Cloning and sequencing of two enterococcal glpK genes and regulation of the encoded glycerol kinases by phosphoenolpyruvate-dependent, phosphotransferase system-catalyzed phosphorylation of a single histidyl residue.
The Journal of biological chemistry 1997;272(22):14166-74.
1997: R Gösseringer; E Küster; A Galinier; Josef Deutscher; Wolfgang Hillen
Cooperative and non-cooperative DNA binding modes of catabolite control protein CcpA from Bacillus megaterium result from sensing two different signals.
Journal of molecular biology 1997;266(4):665-76.
1997: Véronique Charrier; Josef Deutscher; Anne Galinier; Isabelle Martin-Verstraete
Protein phosphorylation chain of a Bacillus subtilis fructose-specific phosphotransferase system and its participation in regulation of the expression of the lev operon.
Biochemistry 1997;36(5):1163-72.
1997: Josef Deutscher; C Fischer; Véronique Charrier; Anne Galinier; Cordula Lindner; Emmanuelle Darbon; V Dossonnet
Regulation of carbon metabolism in gram-positive bacteria by protein phosphorylation.
Folia microbiologica 1997;42(3):171-8.
1996: Jonathan Reizer; U Bergstedt; Anne Galinier; E Küster; Milton H Saier; Wolfgang Hillen; M Steinmetz; Josef Deutscher
Catabolite repression resistance of gnt operon expression in Bacillus subtilis conferred by mutation of His-15, the site of phosphoenolpyruvate-dependent phosphorylation of the phosphocarrier protein HPr.
Journal of bacteriology 1996;178(18):5480-6.
1996: C Fischer; Christophe Geourjon; C Bourson; Josef Deutscher
Cloning and characterization of the Bacillus subtilis prkA gene encoding a novel serine protein kinase.
Gene 1996;168(1):55-60.
1996: Milton H Saier; S Chauvaux; Gregory Cook; Josef Deutscher; Ian Paulsen; Jonathan Reizer; J J Ye
Catabolite repression and inducer control in Gram-positive bacteria.
Microbiology (Reading, England) 1996;142 ( Pt 2)():217-30.
1995: Jörg Stülke; Isabelle Martin-Verstraete; Véronique Charrier; André Klier; Josef Deutscher; Georges Rapoport
The HPr protein of the phosphotransferase system links induction and catabolite repression of the Bacillus subtilis levanase operon.
Journal of bacteriology 1995;177(23):6928-36.
1995: Y Fujita; Y Miwa; Anne Galinier; Josef Deutscher
Specific recognition of the Bacillus subtilis gnt cis-acting catabolite-responsive element by a protein complex formed between CcpA and seryl-phosphorylated HPr.
Molecular microbiology 1995;17(5):953-60.
1995: Milton H Saier; S Chauvaux; Josef Deutscher; Jonathan Reizer; J J Ye
Protein phosphorylation and regulation of carbon metabolism in gram-negative versus gram-positive bacteria.
Trends in biochemical sciences 1995;20(7):267-71.
1995: Josef Deutscher; E Küster; U Bergstedt; Véronique Charrier; Wolfgang Hillen
Protein kinase-dependent HPr/CcpA interaction links glycolytic activity to carbon catabolite repression in gram-positive bacteria.
Molecular microbiology 1995;15(6):1049-53.
1994: Josef Deutscher; Jonathan Reizer; C Fischer; Anne Galinier; M H Saier; M Steinmetz
Loss of protein kinase-catalyzed phosphorylation of HPr, a phosphocarrier protein of the phosphotransferase system, by mutation of the ptsH gene confers catabolite repression resistance to several catabolic genes of Bacillus subtilis.
Journal of bacteriology 1994;176(11):3336-44.
1994: T Kitlar; F Döring; D F Diedrich; R Frank; H Wallmeier; Rolf Kinne; Josef Deutscher
Interaction of phlorizin, a potent inhibitor of the Na+/D-glucose cotransporter, with the NADPH-binding site of mammalian catalases.
Protein science : a publication of the Protein Society 1994;3(4):696-700.
1993: Josef Deutscher; B Bauer; H Sauerwald
Regulation of glycerol metabolism in Enterococcus faecalis by phosphoenolpyruvate-dependent phosphorylation of glycerol kinase catalyzed by enzyme I and HPr of the phosphotransferase system.
Journal of bacteriology 1993;175(12):3730-3.
1993: Jonathan Reizer; A H Romano; Josef Deutscher
The role of phosphorylation of HPr, a phosphocarrier protein of the phosphotransferase system, in the regulation of carbon metabolism in gram-positive bacteria.
Journal of cellular biochemistry 1993;51(1):19-24.
1992: Jonathan Reizer; S L Sutrina; L F Wu; Josef Deutscher; P Reddy; Milton H Saier
Functional interactions between proteins of the phosphoenolpyruvate:sugar phosphotransferase systems of Bacillus subtilis and Escherichia coli.
The Journal of biological chemistry 1992;267(13):9158-69.
1991: A Reizer; Josef Deutscher; Milton H Saier; Jonathan Reizer
Analysis of the gluconate (gnt) operon of Bacillus subtilis.
Molecular microbiology 1991;5(5):1081-9.
1989: Jonathan Reizer; Josef Deutscher; Milton H Saier
Metabolite-sensitive, ATP-dependent, protein kinase-catalyzed phosphorylation of HPr, a phosphocarrier protein of the phosphotransferase system in gram-positive bacteria.
Biochimie 1989;71(9-10):989-96.
1989: Josef Deutscher; G Sossna; G Gonzy-Treboul
Regulatory functions of the phosphocarrier protein HPr of the phosphoenol pyruvate-dependent phosphotransferase system in gram-positive bacteria.
FEMS microbiology reviews 1989;5(1-2):167-74.
1988: R Eisermann; Josef Deutscher; G Gonzy-Treboul; Wolfgang Hengstenberg
Site-directed mutagenesis with the ptsH gene of Bacillus subtilis. Isolation and characterization of heat-stable proteins altered at the ATP-dependent regulatory phosphorylation site.
The Journal of biological chemistry 1988;263(32):17050-4.
1988: B Reiche; R Frank; Josef Deutscher; N Meyer; Wolfgang Hengstenberg
Staphylococcal phosphoenolpyruvate-dependent phosphotransferase system: purification and characterization of the mannitol-specific enzyme IIImtl of Staphylococcus aureus and Staphylococcus carnosus and homology with the enzyme IImtl of Escherichia coli.
Biochemistry 1988;27(17):6512-6.
1988: T Kitlar; A I Morrison; Rolf Kinne; Josef Deutscher
Purification of a putative Na+/D-glucose cotransporter from pig kidney brush border membranes on a phlorizin affinity column.
FEBS letters 1988;234(1):115-9.
1988: E Bruce Waygood; K Pasloske; Louis T J Delbaere; Josef Deutscher; Wolfgang Hengstenberg
Characterization of the 1-phosphohistidinyl residue in the phosphocarrier protein HPr of the phosphoenolpyruvate: sugar phosphotransferase system of Streptococcus faecalis.
Biochemistry and cell biology = Biochimie et biologie cellulaire 1988;66(1):76-80.
1988: Jonathan Reizer; Milton H Saier; Josef Deutscher; F Grenier; J Thompson; Wolfgang Hengstenberg
The phosphoenolpyruvate:sugar phosphotransferase system in gram-positive bacteria: properties, mechanism, and regulation.
Critical reviews in microbiology 1988;15(4):297-338.
1986: Josef Deutscher; B Pevec; Konrad Beyreuther; H H Kiltz; Wolfgang Hengstenberg
Streptococcal phosphoenolpyruvate-sugar phosphotransferase system: amino acid sequence and site of ATP-dependent phosphorylation of HPr.
Biochemistry 1986;25(21):6543-51.
1986: Josef Deutscher; H Sauerwald
Stimulation of dihydroxyacetone and glycerol kinase activity in Streptococcus faecalis by phosphoenolpyruvate-dependent phosphorylation catalyzed by enzyme I and HPr of the phosphotransferase system.
Journal of bacteriology 1986;166(3):829-36.
1985: Josef Deutscher; U Kessler; Wolfgang Hengstenberg
Streptococcal phosphoenolpyruvate: sugar phosphotransferase system: purification and characterization of a phosphoprotein phosphatase which hydrolyzes the phosphoryl bond in seryl-phosphorylated histidine-containing protein.
Journal of bacteriology 1985;163(3):1203-9.
1985: Carl Alpert; M Dörschug; D Saffen; R Frank; Josef Deutscher; Wolfgang Hengstenberg
The bacterial phosphoenolpyruvate-dependent phosphotransferase system. Isolation of active site peptides by reversed-phase high-performance liquid chromatography and determination of their primary structure.
Journal of chromatography 1985;326():363-71.
1985: K Stüber; Josef Deutscher; H M Sobek; Wolfgang Hengstenberg; Konrad Beyreuther
Amino acid sequence of the amphiphilic phosphocarrier protein factor IIILac of the lactose-specific phosphotransferase system of Staphylococcus.
Biochemistry 1985;24(5):1164-8.
1985: Carl Alpert; R Frank; K Stüber; Josef Deutscher; Wolfgang Hengstenberg
Phosphoenolpyruvate-dependent protein kinase enzyme I of Streptococcus faecalis: purification and properties of the enzyme and characterization of its active center.
Biochemistry 1985;24(4):959-64.
1984: M Dörschug; R Frank; H R Kalbitzer; Wolfgang Hengstenberg; Josef Deutscher
Phosphoenolpyruvate-dependent phosphorylation site in enzyme IIIglc of the Escherichia coli phosphotransferase system.
European journal of biochemistry / FEBS 1984;144(1):113-9.
1982: Josef Deutscher; Konrad Beyreuther; H M Sobek; K Stüber; Wolfgang Hengstenberg
Phosphoenolpyruvate-dependent phosphotransferase system of Staphylococcus aureus: factor IIIlac, a trimeric phospho-carrier protein that also acts as a phase transfer catalyst.
Biochemistry 1982;21(20):4867-73.
1982: H R Kalbitzer; Wolfgang Hengstenberg; Paul Rösch; P Muss; P Bernsmann; Roswitha Engelmann; M Dörschug; Josef Deutscher
HPr proteins of different microorganisms studied by hydrogen-1 high-resolution nuclear magnetic resonance: similarities of structures and mechanisms.
Biochemistry 1982;21(12):2879-85.
1982: P Bernsmann; Carl Alpert; P Muss; Josef Deutscher; Wolfgang Hengstenberg
The bacterial PEP-dependent phosphotransferase system mechanism of gluconate phosphorylation in Streptococcus faecalis.
FEBS letters 1982;138(1):101-3.
1981: H R Kalbitzer; Josef Deutscher; Wolfgang Hengstenberg; Paul Rösch
Phosphoenolpyruvate-dependent phosphotransferase system of Staphylococcus aureus: 1H nuclear magnetic resonance studies on phosphorylated and unphosphorylated factor IIIlac and its interaction with the phosphocarrier protein HPr.
Biochemistry 1981;20(21):6178-85.