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Peter Devreotes

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Living Beings

Dictyostelium

Chemicals & Drugs

Physiology

Concepts & Ideas

Anatomy

Cell Membrane

Genes & Molecular Sequences

Phenomena

Phosphorylation

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Co-Publications
Name
15
Borleis, Jane
13
Parent, Carole
12
Firtel, Richard
11
Iijima, Miho
11
van haastert, peter
10
Schaap, Pauline
9
Kimmel, Alan
9
Janetopoulos, Chris
8
Caterina, Michael
8
Iglesias, Pablo
8
Saxe, Charles
7
Kim, Joo Young
7
Long, Yu
7
Huang, Yi Elaine
5
Vazquez, Francisca

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Publications

TOP 3
Rahdar Meghdad; Inoue Takanari; Meyer Tobias; Zhang Jin; Vazquez Francisca; Devreotes Peter N
A phosphorylation-dependent intramolecular interaction regulates the membrane association and activity of the tumor suppressor PTEN.
Kamimura Yoichiro; Tang Ming; Devreotes Peter
Assays for chemotaxis and chemoattractant-stimulated TorC2 activation and PKB substrate phosphorylation in Dictyostelium.
Tang Linnan; Franca-Koh Jonathan; Xiong Yuan; Chen Mei-Yu; Long Yu; Bickford Ross M; Knecht David A; Iglesias Pablo A; Devreotes Peter N
tsunami, the Dictyostelium homolog of the Fused kinase, is required for polarization and chemotaxis.

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All Publications

2009: Rahdar Meghdad; Inoue Takanari; Meyer Tobias; Zhang Jin; Vazquez Francisca; Devreotes Peter N
A phosphorylation-dependent intramolecular interaction regulates the membrane association and activity of the tumor suppressor PTEN.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(2):480-5.
2009: Kamimura Yoichiro; Tang Ming; Devreotes Peter
Assays for chemotaxis and chemoattractant-stimulated TorC2 activation and PKB substrate phosphorylation in Dictyostelium.
Methods in molecular biology (Clifton, N.J.) 2009;571():255-70.
2008: Tang Linnan; Franca-Koh Jonathan; Xiong Yuan; Chen Mei-Yu; Long Yu; Bickford Ross M; Knecht David A; Iglesias Pablo A; Devreotes Peter N
tsunami, the Dictyostelium homolog of the Fused kinase, is required for polarization and chemotaxis.
Genes & development 2008;22(16):2278-90.
2008: Kamimura Yoichiro; Xiong Yuan; Iglesias Pablo A; Hoeller Oliver; Bolourani Parvin; Devreotes Peter N
PIP3-independent activation of TorC2 and PKB at the cell's leading edge mediates chemotaxis.
Current biology : CB 2008;18(14):1034-43.
2008: Iglesias Pablo A; Devreotes Peter N
Navigating through models of chemotaxis.
Current opinion in cell biology 2008;20(1):35-40.
2007: Sasaki Atsuo T; Janetopoulos Chris; Lee Susan; Charest Pascale G; Takeda Kosuke; Sundheimer Lauren W; Meili Ruedi; Devreotes Peter N; Firtel Richard A
G protein-independent Ras/PI3K/F-actin circuit regulates basic cell motility.
The Journal of cell biology 2007;178(2):185-91.
2007: Chen Lingfeng; Iijima Miho; Tang Ming; Landree Mark A; Huang Yi Elaine; Xiong Yuan; Iglesias Pablo A; Devreotes Peter N
PLA2 and PI3K/PTEN pathways act in parallel to mediate chemotaxis.
Developmental cell 2007;12(4):603-14.
2007: Franca-Koh Jonathan; Kamimura Yoichiro; Devreotes Peter N
Leading-edge research: PtdIns(3,4,5)P3 and directed migration.
Nature cell biology 2007;9(1):15-7.
2006: Somesh Baggavalli P; Vlahou Georgia; Iijima Miho; Insall Robert H; Devreotes Peter; Rivero Francisco
RacG regulates morphology, phagocytosis, and chemotaxis.
Eukaryotic cell 2006;5(10):1648-63.
2006: Somesh Baggavalli P; Neffgen Carola; Iijima Miho; Devreotes Peter; Rivero Francisco
Dictyostelium RacH regulates endocytic vesicular trafficking and is required for localization of vacuolin.
Traffic (Copenhagen, Denmark) 2006;7(9):1194-212.
2006: Willard Stacey S; Devreotes Peter N
Signaling pathways mediating chemotaxis in the social amoeba, Dictyostelium discoideum.
European journal of cell biology 2006;85(9-10):897-904.
2006: Janetopoulos Chris; Devreotes Peter
Phosphoinositide signaling plays a key role in cytokinesis.
The Journal of cell biology 2006;174(4):485-90.
2006: Franca-Koh Jonathan; Kamimura Yoichiro; Devreotes Peter
Navigating signaling networks: chemotaxis in Dictyostelium discoideum.
Current opinion in genetics & development 2006;16(4):333-8.
2006: Zhao Min; Song Bing; Pu Jin; Wada Teiji; Reid Brian; Tai Guangping; Wang Fei; Guo Aihua; Walczysko Petr; Gu Yu; Sasaki Takehiko; Suzuki Akira; Forrester John V; Bourne Henry R; Devreotes Peter N; McCaig Colin D; Penninger Josef M
Electrical signals control wound healing through phosphatidylinositol-3-OH kinase-gamma and PTEN.
Nature 2006;442(7101):457-60.
2006: Vazquez Francisca; Devreotes Peter
Regulation of PTEN function as a PIP3 gatekeeper through membrane interaction.
Cell cycle (Georgetown, Tex.) 2006;5(14):1523-7.
2006: Loovers Harriët M; Postma Marten; Keizer-Gunnink Ineke; Huang Yi Elaine; Devreotes Peter N; van Haastert Peter J M
Distinct roles of PI(3,4,5)P3 during chemoattractant signaling in Dictyostelium: a quantitative in vivo analysis by inhibition of PI3-kinase.
Molecular biology of the cell 2006;17(4):1503-13.
2006: Vazquez Francisca; Matsuoka Satomi; Sellers William R; Yanagida Toshio; Ueda Masahiro; Devreotes Peter N
Tumor suppressor PTEN acts through dynamic interaction with the plasma membrane.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(10):3633-8.
2006: Matsuoka Satomi; Iijima Miho; Watanabe Tomonobu M; Kuwayama Hidekazu; Yanagida Toshio; Devreotes Peter N; Ueda Masahiro
Single-molecule analysis of chemoattractant-stimulated membrane recruitment of a PH-domain-containing protein.
Journal of cell science 2006;119(Pt 6):1071-9.
2005: Fache Sébastien; Dalous Jérémie; Engelund Mads; Hansen Christian; Chamaraux François; Fourcade Bertrand; Satre Michel; Devreotes Peter; Bruckert Franz
Calcium mobilization stimulates Dictyostelium discoideum shear-flow-induced cell motility.
Journal of cell science 2005;118(Pt 15):3445-57.
2005: Janetopoulos Chris; Borleis Jane; Vazquez Francisca; Iijima Miho; Devreotes Peter
Temporal and spatial regulation of phosphoinositide signaling mediates cytokinesis.
Developmental cell 2005;8(4):467-77.
2004: Ma Lan; Janetopoulos Chris; Yang Liu; Devreotes Peter N; Iglesias Pablo A
Two complementary, local excitation, global inhibition mechanisms acting in parallel can explain the chemoattractant-induced regulation of PI(3,4,5)P3 response in dictyostelium cells.
Biophysical journal 2004;87(6):3764-74.
2004: Franca-Koh Jonathan; Devreotes Peter N
Moving forward: mechanisms of chemoattractant gradient sensing.
Physiology (Bethesda, Md.) 2004;19():300-8.
2004: Van Haastert Peter J M; Devreotes Peter N
Chemotaxis: signalling the way forward.
Nature reviews. Molecular cell biology 2004;5(8):626-34.
2004: Hynes Thomas R; Tang Linnan; Mervine Stacy M; Sabo Jonathan L; Yost Evan A; Devreotes Peter N; Berlot Catherine H
Visualization of G protein betagamma dimers using bimolecular fluorescence complementation demonstrates roles for both beta and gamma in subcellular targeting.
The Journal of biological chemistry 2004;279(29):30279-86.
2004: Janetopoulos Chris; Ma Lan; Devreotes Peter N; Iglesias Pablo A
Chemoattractant-induced phosphatidylinositol 3,4,5-trisphosphate accumulation is spatially amplified and adapts, independent of the actin cytoskeleton.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(24):8951-6.
2004: Montell Craig; Devreotes Peter
From protein dynamics to animal behavior: new insights into complex cell regulatory mechanisms.
Current opinion in cell biology 2004;16(2):115-8.
2004: Iijima Miho; Huang Yi Elaine; Luo Hongbo R; Vazquez Francisca; Devreotes Peter N
Novel mechanism of PTEN regulation by its phosphatidylinositol 4,5-bisphosphate binding motif is critical for chemotaxis.
The Journal of biological chemistry 2004;279(16):16606-13.
2004: Kutscher Brett; Devreotes Peter; Iglesias Pablo A
Local excitation, global inhibition mechanism for gradient sensing: an interactive applet.
Science's STKE : signal transduction knowledge environment 2004;2004(219):pl3.
2004: Manahan Carol L; Iglesias Pablo A; Long Yu; Devreotes Peter N
Chemoattractant signaling in dictyostelium discoideum.
Annual review of cell and developmental biology 2004;20():223-53.
2004: Landree Mark A; Devreotes Peter N
Analyzing chemotaxis using Dictyostelium discoideum as a model system.
Methods in molecular biology (Clifton, N.J.) 2004;239():91-104.
2003: Chen Lingfeng; Janetopoulos Chris; Huang Yi Elaine; Iijima Miho; Borleis Jane; Devreotes Peter N
Two phases of actin polymerization display different dependencies on PI(3,4,5)P3 accumulation and have unique roles during chemotaxis.
Molecular biology of the cell 2003;14(12):5028-37.
2003: Luo Hongbo R; Huang Yi Elaine; Chen Jianmeng C; Saiardi Adolfo; Iijima Miho; Ye Keqiang; Huang Yunfei; Nagata Eiichiro; Devreotes Peter; Snyder Solomon H
Inositol pyrophosphates mediate chemotaxis in Dictyostelium via pleckstrin homology domain-PtdIns(3,4,5)P3 interactions.
Cell 2003;114(5):559-72.
2003: Devreotes Peter; Janetopoulos Chris
Eukaryotic chemotaxis: distinctions between directional sensing and polarization.
The Journal of biological chemistry 2003;278(23):20445-8.
2003: Huang Yi Elaine; Iijima Miho; Parent Carole A; Funamoto Satoru; Firtel Richard A; Devreotes Peter
Receptor-mediated regulation of PI3Ks confines PI(3,4,5)P3 to the leading edge of chemotaxing cells.
Molecular biology of the cell 2003;14(5):1913-22.
2002: Gilman Alfred G; Simon Melvin I; Bourne Henry R; Harris Bruce A; Long Rochelle; Ross Elliott M; Stull James T; Taussig Ronald; Bourne Henry R; Arkin Adam P; Cobb Melanie H; Cyster Jason G; Devreotes Peter N; Ferrell James E; Fruman David; Gold Michael; Weiss Arthur; Stull James T; Berridge Michael J; Cantley Lewis C; Catterall William A; Coughlin Shaun R; Olson Eric N; Smith Temple F; Brugge Joan S; Botstein David; Dixon Jack E; Hunter Tony; Lefkowitz Robert J; Pawson Anthony J; Sternberg Paul W; Varmus Harold; Subramaniam Shankar; Sinkovits Robert S; Li Joshua; Mock Dennis; Ning Yuhong; Saunders Brian; Sternweis Paul C; Hilgemann Donald; Scheuermann Richard H; DeCamp Dianne; Hsueh Robert; Lin Keng-Mean; Ni Yan; Seaman William E; Simpson Paul C; O'Connell Timothy D; Roach Tamara; Simon Melvin I; Choi Sangdun; Eversole-Cire Pamela; Fraser Iain; Mumby Marc C; Zhao Yingming; Brekken Deirdre; Shu Hongjun; Meyer Tobias; Chandy Grischa; Heo Won Do; Liou Jen; O'Rourke Nancy; Verghese Mary; Mumby Susanne M; Han Heping; Brown H Alex; Forrester Jeffrey S; Ivanova Pavlina; Milne Stephen B; Casey Patrick J; Harden T Kendall; Arkin Adam P; Doyle John; Gray Martha L; Meyer Tobias; Michnick Stephen; Schmidt Martin A; Toner Mehmet; Tsien Roger Y; Natarajan Madhusudan; Ranganathan Rama; Sambrano Gilberto R;
Overview of the Alliance for Cellular Signaling.
Nature 2002;420(6916):703-6.
2002: Pergolizzi Barbara; Peracino Barbara; Silverman James; Ceccarelli Adriano; Noegel Angelika; Devreotes Peter; Bozzaro Salvatore
Temperature-sensitive inhibition of development in Dictyostelium due to a point mutation in the piaA gene.
Developmental biology 2002;251(1):18-26.
2002: Iijima Miho; Huang Yi Elaine; Devreotes Peter
Temporal and spatial regulation of chemotaxis.
Developmental cell 2002;3(4):469-78.
2002: Janetopoulos Chris; Devreotes Peter
Monitoring receptor-mediated activation of heterotrimeric G-proteins by fluorescence resonance energy transfer.
Methods (San Diego, Calif.) 2002;27(4):366-73.
2002: Zhang Ning; Long Yu; Devreotes Peter N
Ege A, a novel C2 domain containing protein, is essential for GPCR-mediated gene expression in dictyostelium.
Developmental biology 2002;248(1):1-12.
2002: Dormann Dirk; Weijer Gerti; Parent Carole A; Devreotes Peter N; Weijer Cornelis J
Visualizing PI3 kinase-mediated cell-cell signaling during Dictyostelium development.
Current biology : CB 2002;12(14):1178-88.
2002: Zhao Min; Jin Tian; McCaig Colin D; Forrester John V; Devreotes Peter N
Genetic analysis of the role of G protein-coupled receptor signaling in electrotaxis.
The Journal of cell biology 2002;157(6):921-7.
2002: Iijima Miho; Devreotes Peter
Tumor suppressor PTEN mediates sensing of chemoattractant gradients.
Cell 2002;109(5):599-610.
2002: Bankir Lise; Ahloulay Mina; Devreotes Peter N; Parent Carole A
Extracellular cAMP inhibits proximal reabsorption: are plasma membrane cAMP receptors involved?
American journal of physiology. Renal physiology 2002;282(3):F376-92.
2002: Parent Carole A; Borleis Jane; Devreotes Peter N
Regulation of adenylyl cyclases by a region outside the minimally functional cytoplasmic domains.
The Journal of biological chemistry 2002;277(2):1354-60.
2001: Ueda M; Sako Y; Tanaka T; Devreotes P; Yanagida T
Single-molecule analysis of chemotactic signaling in Dictyostelium cells.
Science (New York, N.Y.) 2001;294(5543):864-7.
2001: Zhang N; Long Y; Devreotes P N
Ggamma in dictyostelium: its role in localization of gbetagamma to the membrane is required for chemotaxis in shallow gradients.
Molecular biology of the cell 2001;12(10):3204-13.
2001: van Es S; Weening K E; Devreotes P N
The protein kinase YakA regulates g-protein-linked signaling responses during growth and development of Dictyostelium.
The Journal of biological chemistry 2001;276(33):30761-5.
2001: Dormann D; Kim J Y; Devreotes P N; Weijer C J
cAMP receptor affinity controls wave dynamics, geometry and morphogenesis in Dictyostelium.
Journal of cell science 2001;114(Pt 13):2513-23.
2001: Verkerke-van Wijk I; Fukuzawa M; Devreotes P N; Schaap P
Adenylyl cyclase A expression is tip-specific in Dictyostelium slugs and directs StatA nuclear translocation and CudA gene expression.
Developmental biology 2001;234(1):151-60.
2001: Briscoe C; Moniakis J; Kim J Y; Brown J M; Hereld D; Devreotes P N; Firtel R A
The phosphorylated C-terminus of cAR1 plays a role in cell-type-specific gene expression and STATa tyrosine phosphorylation.
Developmental biology 2001;233(1):225-36.
2001: Janetopoulos C; Jin T; Devreotes P
Receptor-mediated activation of heterotrimeric G-proteins in living cells.
Science (New York, N.Y.) 2001;291(5512):2408-11.
2001: van Es S; Wessels D; Soll D R; Borleis J; Devreotes P N
Tortoise, a novel mitochondrial protein, is required for directional responses of Dictyostelium in chemotactic gradients.
The Journal of cell biology 2001;152(3):621-32.
2000: Garcia M X; Foote C; van Es S; Devreotes P N; Alexander S; Alexander H
Differential developmental expression and cell type specificity of Dictyostelium catalases and their response to oxidative stress and UV-light.
Biochimica et biophysica acta 2000;1492(2-3):295-310.
2000: Patel H; Guo K; Parent C; Gross J; Devreotes P N; Weijer C J
A temperature-sensitive adenylyl cyclase mutant of Dictyostelium.
The EMBO journal 2000;19(10):2247-56.
2000: Jin T; Zhang N; Long Y; Parent C A; Devreotes P N
Localization of the G protein betagamma complex in living cells during chemotaxis.
Science (New York, N.Y.) 2000;287(5455):1034-6.
1999: van Es S; Devreotes P N
Molecular basis of localized responses during chemotaxis in amoebae and leukocytes.
Cellular and molecular life sciences : CMLS 1999;55(10):1341-51.
1999: Parent C A; Devreotes P N
A cell's sense of direction.
Science (New York, N.Y.) 1999;284(5415):765-70.
1999: Xiao Z; Yao Y; Long Y; Devreotes P
Desensitization of G-protein-coupled receptors. agonist-induced phosphorylation of the chemoattractant receptor cAR1 lowers its intrinsic affinity for cAMP.
The Journal of biological chemistry 1999;274(3):1440-8.
1998: Vithalani K K; Parent C A; Thorn E M; Penn M; Larochelle D A; Devreotes P N; De Lozanne A
Identification of darlin, a Dictyostelium protein with Armadillo-like repeats that binds to small GTPases and is important for the proper aggregation of developing cells.
Molecular biology of the cell 1998;9(11):3095-106.
1998: Parent C A; Blacklock B J; Froehlich W M; Murphy D B; Devreotes P N
G protein signaling events are activated at the leading edge of chemotactic cells.
Cell 1998;95(1):81-91.
1998: Jin T; Amzel M; Devreotes P N; Wu L
Selection of gbeta subunits with point mutations that fail to activate specific signaling pathways in vivo: dissecting cellular responses mediated by a heterotrimeric G protein in Dictyostelium discoideum.
Molecular biology of the cell 1998;9(10):2949-61.
1998: Verkerke-Van Wijk I; Kim J Y; Brandt R; Devreotes P N; Schaap P
Functional promiscuity of gene regulation by serpentine receptors in Dictyostelium discoideum.
Molecular and cellular biology 1998;18(10):5744-9.
1998: Jin T; Soede R D; Liu J; Kimmel A R; Devreotes P N; Schaap P
Temperature-sensitive Gbeta mutants discriminate between G protein-dependent and -independent signaling mediated by serpentine receptors.
The EMBO journal 1998;17(17):5076-84.
1998: Peracino B; Borleis J; Jin T; Westphal M; Schwartz J M; Wu L; Bracco E; Gerisch G; Devreotes P; Bozzaro S
G protein beta subunit-null mutants are impaired in phagocytosis and chemotaxis due to inappropriate regulation of the actin cytoskeleton.
The Journal of cell biology 1998;141(7):1529-37.
1998: Kim J Y; Borleis J A; Devreotes P N
Switching of chemoattractant receptors programs development and morphogenesis in Dictyostelium: receptor subtypes activate common responses at different agonist concentrations.
Developmental biology 1998;197(1):117-28.
1997: Chen M Y; Long Y; Devreotes P N
A novel cytosolic regulator, Pianissimo, is required for chemoattractant receptor and G protein-mediated activation of the 12 transmembrane domain adenylyl cyclase in Dictyostelium.
Genes & development 1997;11(23):3218-31.
1997: Kim J Y; Soede R D; Schaap P; Valkema R; Borleis J A; Van Haastert P J; Devreotes P N; Hereld D
Phosphorylation of chemoattractant receptors is not essential for chemotaxis or termination of G-protein-mediated responses.
The Journal of biological chemistry 1997;272(43):27313-8.
1997: Xiao Z; Zhang N; Murphy D B; Devreotes P N
Dynamic distribution of chemoattractant receptors in living cells during chemotaxis and persistent stimulation.
The Journal of cell biology 1997;139(2):365-74.
1997: Zigmond S H; Joyce M; Borleis J; Bokoch G M; Devreotes P N
Regulation of actin polymerization in cell-free systems by GTPgammaS and Cdc42.
The Journal of cell biology 1997;138(2):363-74.
1997: Xiao Z; Devreotes P N
Identification of detergent-resistant plasma membrane microdomains in dictyostelium: enrichment of signal transduction proteins.
Molecular biology of the cell 1997;8(5):855-69.
1997: Mann S K; Brown J M; Briscoe C; Parent C; Pitt G; Devreotes P N; Firtel R A
Role of cAMP-dependent protein kinase in controlling aggregation and postaggregative development in Dictyostelium.
Developmental biology 1997;183(2):208-21.
1997: Aubry L; Maeda M; Insall R; Devreotes P N; Firtel R A
The Dictyostelium mitogen-activated protein kinase ERK2 is regulated by Ras and cAMP-dependent protein kinase (PKA) and mediates PKA function.
The Journal of biological chemistry 1997;272(7):3883-6.
1997: Milne J L; Caterina M J; Devreotes P N
Random mutagenesis of the cAMP chemoattractant receptor, cAR1, of Dictyostelium. Evidence for multiple states of activation.
The Journal of biological chemistry 1997;272(4):2069-76.
1997: Kim J Y; Caterina M J; Milne J L; Lin K C; Borleis J A; Devreotes P N
Random mutagenesis of the cAMP chemoattractant receptor, cAR1, of Dictyostelium. Mutant classes that cause discrete shifts in agonist affinity and lock the receptor in a novel activational intermediate.
The Journal of biological chemistry 1997;272(4):2060-8.
1997: Milne J L; Kim J Y; Devreotes P N
Chemoattractant receptor signaling: G protein-dependent and -independent pathways.
Advances in second messenger and phosphoprotein research 1997;31():83-104.
1996: van Es S; Virdy K J; Pitt G S; Meima M; Sands T W; Devreotes P N; Cotter D A; Schaap P
Adenylyl cyclase G, an osmosensor controlling germination of Dictyostelium spores.
The Journal of biological chemistry 1996;271(39):23623-5.
1996: Parent C A; Devreotes P N
Constitutively active adenylyl cyclase mutant requires neither G proteins nor cytosolic regulators.
The Journal of biological chemistry 1996;271(31):18333-6.
1996: Insall R H; Borleis J; Devreotes P N
The aimless RasGEF is required for processing of chemotactic signals through G-protein-coupled receptors in Dictyostelium.
Current biology : CB 1996;6(6):719-29.
1996: Kim J Y; Haastert P V; Devreotes P N
Social senses: G-protein-coupled receptor signaling pathways in Dictyostelium discoideum.
Chemistry & biology 1996;3(4):239-43.
1996: Chen M Y; Insall R H; Devreotes P N
Signaling through chemoattractant receptors in Dictyostelium.
Trends in genetics : TIG 1996;12(2):52-7.
1996: Maeda M; Aubry L; Insall R; Gaskins C; Devreotes P N; Firtel R A
Seven helix chemoattractant receptors transiently stimulate mitogen-activated protein kinase in Dictyostelium. Role of heterotrimeric G proteins.
The Journal of biological chemistry 1996;271(7):3351-4.
1996: Parent C A; Devreotes P N
Molecular genetics of signal transduction in Dictyostelium.
Annual review of biochemistry 1996;65():411-40.
1995: Parent C A; Devreotes P N
Isolation of inactive and G protein-resistant adenylyl cyclase mutants using random mutagenesis.
The Journal of biological chemistry 1995;270(39):22693-6.
1995: Wu L; Valkema R; Van Haastert P J; Devreotes P N
The G protein beta subunit is essential for multiple responses to chemoattractants in Dictyostelium.
The Journal of cell biology 1995;129(6):1667-75.
1995: Lilly P J; Devreotes P N
Chemoattractant and GTP gamma S-mediated stimulation of adenylyl cyclase in Dictyostelium requires translocation of CRAC to membranes.
The Journal of cell biology 1995;129(6):1659-65.
1995: Caterina M J; Devreotes P N; Borleis J; Hereld D
Agonist-induced loss of ligand binding is correlated with phosphorylation of cAR1, a G protein-coupled chemoattractant receptor from Dictyostelium.
The Journal of biological chemistry 1995;270(15):8667-72.
1995: Caterina M J; Hereld D; Devreotes P N
Occupancy of the Dictyostelium cAMP receptor, cAR1, induces a reduction in affinity which depends upon COOH-terminal serine residues.
The Journal of biological chemistry 1995;270(9):4418-23.
1995: Milne J L; Wu L; Caterina M J; Devreotes P N
Seven helix cAMP receptors stimulate Ca2+ entry in the absence of functional G proteins in Dictyostelium.
The Journal of biological chemistry 1995;270(11):5926-31.
1994: Kim J Y; Devreotes P N
Random chimeragenesis of G-protein-coupled receptors. Mapping the affinity of the cAMP chemoattractant receptors in Dictyostelium.
The Journal of biological chemistry 1994;269(46):28724-31.
1994: Insall R; Kuspa A; Lilly P J; Shaulsky G; Levin L R; Loomis W F; Devreotes P
CRAC, a cytosolic protein containing a pleckstrin homology domain, is required for receptor and G protein-mediated activation of adenylyl cyclase in Dictyostelium.
The Journal of cell biology 1994;126(6):1537-45.
1994: Chen M Y; Devreotes P N; Gundersen R E
Serine 113 is the site of receptor-mediated phosphorylation of the Dictyostelium G protein alpha-subunit G alpha 2.
The Journal of biological chemistry 1994;269(33):20925-30.
1994: Soede R D; Insall R H; Devreotes P N; Schaap P
Extracellular cAMP can restore development in Dictyostelium cells lacking one, but not two subtypes of early cAMP receptors (cARs). Evidence for involvement of cAR1 in aggregative gene expression.
Development (Cambridge, England) 1994;120(7):1997-2002.
1994: Insall R H; Soede R D; Schaap P; Devreotes P N
Two cAMP receptors activate common signaling pathways in Dictyostelium.
Molecular biology of the cell 1994;5(6):703-11.
1994: Wu L; Gaskins C; Zhou K; Firtel R A; Devreotes P N
Cloning and targeted mutations of G alpha 7 and G alpha 8, two developmentally regulated G protein alpha-subunit genes in Dictyostelium.
Molecular biology of the cell 1994;5(6):691-702.
1994: Lilly P J; Devreotes P N
Identification of CRAC, a cytosolic regulator required for guanine nucleotide stimulation of adenylyl cyclase in Dictyostelium.
The Journal of biological chemistry 1994;269(19):14123-9.
1994: Hereld D; Vaughan R; Kim J Y; Borleis J; Devreotes P
Localization of ligand-induced phosphorylation sites to serine clusters in the C-terminal domain of the Dictyostelium cAMP receptor, cAR1.
The Journal of biological chemistry 1994;269(9):7036-44.
1994: Devreotes P N
G protein-linked signaling pathways control the developmental program of Dictyostelium.
Neuron 1994;12(2):235-41.
1994: Caterina M J; Milne J L; Devreotes P N
Mutation of the third intracellular loop of the cAMP receptor, cAR1, of Dictyostelium yields mutants impaired in multiple signaling pathways.
The Journal of biological chemistry 1994;269(2):1523-32.
1993: Pitt G S; Brandt R; Lin K C; Devreotes P N; Schaap P
Extracellular cAMP is sufficient to restore developmental gene expression and morphogenesis in Dictyostelium cells lacking the aggregation adenylyl cyclase (ACA).
Genes & development 1993;7(11):2172-80.
1993: Lilly P; Wu L; Welker D L; Devreotes P N
A G-protein beta-subunit is essential for Dictyostelium development.
Genes & development 1993;7(6):986-95.
1993: Milne J L; Devreotes P N
The surface cyclic AMP receptors, cAR1, cAR2, and cAR3, promote Ca2+ influx in Dictyostelium discoideum by a G alpha 2-independent mechanism.
Molecular biology of the cell 1993;4(3):283-92.
1993: Saxe C L; Ginsburg G T; Louis J M; Johnson R; Devreotes P N; Kimmel A R
CAR2, a prestalk cAMP receptor required for normal tip formation and late development of Dictyostelium discoideum.
Genes & development 1993;7(2):262-72.
1993: Johnson R L; Saxe C L; Gollop R; Kimmel A R; Devreotes P N
Identification and targeted gene disruption of cAR3, a cAMP receptor subtype expressed during multicellular stages of Dictyostelium development.
Genes & development 1993;7(2):273-82.
1992: Pupillo M; Insall R; Pitt G S; Devreotes P N
Multiple cyclic AMP receptors are linked to adenylyl cyclase in Dictyostelium.
Molecular biology of the cell 1992;3(11):1229-34.
1992: Van Haastert P J; Wang M; Bominaar A A; Devreotes P N; Schaap P
cAMP-induced desensitization of surface cAMP receptors in Dictyostelium: different second messengers mediate receptor phosphorylation, loss of ligand binding, degradation of receptor, and reduction of receptor mRNA levels.
Molecular biology of the cell 1992;3(6):603-12.
1992: Pitt G S; Milona N; Borleis J; Lin K C; Reed R R; Devreotes P N
Structurally distinct and stage-specific adenylyl cyclase genes play different roles in Dictyostelium development.
Cell 1992;69(2):305-15.
1992: Johnson R L; Van Haastert P J; Kimmel A R; Saxe C L; Jastorff B; Devreotes P N
The cyclic nucleotide specificity of three cAMP receptors in Dictyostelium.
The Journal of biological chemistry 1992;267(7):4600-7.
1992: Johnson R L; Gundersen R; Hereld D; Pitt G S; Tugendreich S; Saxe C L; Kimmel A R; Devreotes P N
G-protein-linked signaling pathways mediate development in Dictyostelium.
Cold Spring Harbor symposia on quantitative biology 1992;57():169-76.
1992: Hereld D; Devreotes P N
The cAMP receptor family of Dictyostelium.
International review of cytology 1992;137B():35-47.
1991: Caterina M J; Devreotes P N
Molecular insights into eukaryotic chemotaxis.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1991;5(15):3078-85.
1991: Wu L J; Devreotes P N
Dictyostelium transiently expresses eight distinct G-protein alpha-subunits during its developmental program.
Biochemical and biophysical research communications 1991;179(3):1141-7.
1991: Johnson R L; Vaughan R A; Caterina M J; Van Haastert P J; Devreotes P N
Overexpression of the cAMP receptor 1 in growing Dictyostelium cells.
Biochemistry 1991;30(28):6982-6.
1991: Sun T J; Devreotes P N
Gene targeting of the aggregation stage cAMP receptor cAR1 in Dictyostelium.
Genes & development 1991;5(4):572-82.
1991: Saxe C L; Johnson R L; Devreotes P N; Kimmel A R
Expression of a cAMP receptor gene of Dictyostelium and evidence for a multigene family.
Genes & development 1991;5(1):1-8.
1991: Saxe C L; Johnson R; Devreotes P N; Kimmel A R
Multiple genes for cell surface cAMP receptors in Dictyostelium discoideum.
Developmental genetics 1991;12(1-2):6-13.
1990: Gundersen R E; Devreotes P N
In vivo receptor-mediated phosphorylation of a G protein in Dictyostelium.
Science (New York, N.Y.) 1990;248(4955):591-3.
1990: Sun T J; Van Haastert P J; Devreotes P N
Surface cAMP receptors mediate multiple responses during development in Dictyostelium: evidenced by antisense mutagenesis.
The Journal of cell biology 1990;110(5):1549-54.
1990: Pitt G S; Gundersen R E; Devreotes P N
Mechanisms of excitation and adaptation in Dictyostelium.
Seminars in cell biology 1990;1(2):99-104.
1990: Pitt G S; Gundersen R E; Lilly P J; Pupillo M B; Vaughan R A; Devreotes P N
G protein-linked signal transduction in aggregating Dictyostelium.
Society of General Physiologists series 1990;45():125-31.
1989: Devreotes P
Dictyostelium discoideum: a model system for cell-cell interactions in development.
Science (New York, N.Y.) 1989;245(4922):1054-8.
1989: Devreotes P
Cell-cell interactions in Dictyostelium development.
Trends in genetics : TIG 1989;5(8):242-5.
1989: Firtel R A; van Haastert P J; Kimmel A R; Devreotes P N
G protein linked signal transduction pathways in development: dictyostelium as an experimental system.
Cell 1989;58(2):235-9.
1989: Pupillo M; Kumagai A; Pitt G S; Firtel R A; Devreotes P N
Multiple alpha subunits of guanine nucleotide-binding proteins in Dictyostelium.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(13):4892-6.
1989: Kumagai A; Pupillo M; Gundersen R; Miake-Lye R; Devreotes P N; Firtel R A
Regulation and function of G alpha protein subunits in Dictyostelium.
Cell 1989;57(2):265-75.
1989: Johnson R L; Gundersen R; Lilly P; Pitt G S; Pupillo M; Sun T J; Vaughan R A; Devreotes P N
G-protein-linked signal transduction systems control development in Dictyostelium.
Development (Cambridge, England) 1989;107 Suppl():75-80.
1988: Vaughan R A; Devreotes P N
Ligand-induced phosphorylation of the cAMP receptor from Dictyostelium discoideum.
The Journal of biological chemistry 1988;263(28):14538-43.
1988: Klein P S; Sun T J; Saxe C L; Kimmel A R; Johnson R L; Devreotes P N
A chemoattractant receptor controls development in Dictyostelium discoideum.
Science (New York, N.Y.) 1988;241(4872):1467-72.
1988: Wang M; Van Haastert P J; Devreotes P N; Schaap P
Localization of chemoattractant receptors on Dictyostelium discoideum cells during aggregation and down-regulation.
Developmental biology 1988;128(1):72-7.
1988: Pitt G S; Devreotes P N
A simple BASIC program allows the rapid entry of DNA nucleotide sequences into personal computers.
BioTechniques 1988;6(2):122-3.
1988: Snaar-Jagalska B E; Devreotes P N; Van Haastert P J
Ligand-induced modification of a surface cAMP receptor of Dictyostelium discoideum does not require its occupancy.
The Journal of biological chemistry 1988;263(2):897-901.
1988: Saxe C L; Klein P; Sun T J; Kimmel A R; Devreotes P N
Structure and expression of the cAMP cell-surface receptor.
Developmental genetics 1988;9(4-5):227-35.
1988: Kumagai A; Mann S K; Pupillo M; Pitt G; Devreotes P N; Firtel R A
A molecular analysis of G proteins and control of early gene expression by the cell-surface cAMP receptor in Dictyostelium.
Cold Spring Harbor symposia on quantitative biology 1988;53 Pt 2():675-85.
1988: Pupillo M; Klein P; Vaughan R; Pitt G; Lilly P; Sun T; Devreotes P; Kumagai A; Firtel R
cAMP receptor and G-protein interactions control development in Dictyostelium.
Cold Spring Harbor symposia on quantitative biology 1988;53 Pt 2():657-65.
1988: Devreotes P N; Zigmond S H
Chemotaxis in eukaryotic cells: a focus on leukocytes and Dictyostelium.
Annual review of cell biology 1988;4():649-86.
1988: Klein P; Theibert A; Devreotes P
Identification and ligand-induced modification of the cAMP receptor in Dictyostelium.
Methods in enzymology 1988;159():267-78.
1987: Berlot C H; Devreotes P N; Spudich J A
Chemoattractant-elicited increases in Dictyostelium myosin phosphorylation are due to changes in myosin localization and increases in kinase activity.
The Journal of biological chemistry 1987;262(8):3918-26.
1987: Klein P; Vaughan R; Borleis J; Devreotes P
The surface cyclic AMP receptor in Dictyostelium. Levels of ligand-induced phosphorylation, solubilization, identification of primary transcript, and developmental regulation of expression.
The Journal of biological chemistry 1987;262(1):358-64.
1987: Klein P; Knox B; Borleis J; Devreotes P
Purification of the surface cAMP receptor in Dictyostelium.
The Journal of biological chemistry 1987;262(1):352-7.
1987: Devreotes P; Fontana D; Klein P; Sherring J; Theibert A
Transmembrane signaling in Dictyostelium.
Methods in cell biology 1987;28():299-331.
1986: Theibert A; Devreotes P N
Surface receptor-mediated activation of adenylate cyclase in Dictyostelium. Regulation by guanine nucleotides in wild-type cells and aggregation deficient mutants.
The Journal of biological chemistry 1986;261(32):15121-5.
1986: Reymond C D; Gomer R H; Nellen W; Theibert A; Devreotes P; Firtel R A
Phenotypic changes induced by a mutated ras gene during the development of Dictyostelium transformants.
Nature 1986;323(6086):340-3.
1986: Segel L A; Goldbeter A; Devreotes P N; Knox B E
A mechanism for exact sensory adaptation based on receptor modification.
Journal of theoretical biology 1986;120(2):151-79.
1986: Knox B E; Devreotes P N; Goldbeter A; Segel L A
A molecular mechanism for sensory adaptation based on ligand-induced receptor modification.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(8):2345-9.
1986: Theibert A; Palmisano M; Jastorff B; Devreotes P
The specificity of the cAMP receptor mediating activation of adenylate cyclase in Dictyostelium discoideum.
Developmental biology 1986;114(2):529-33.
1986: Fontana D; Wong T Y; Theibert A; Devreotes P
Cell-cell interactions in the development of Dictyostelium.
Developmental biology (New York, N.Y. : 1985) 1986;3():261-81.
1985: Berlot C H; Spudich J A; Devreotes P N
Chemoattractant-elicited increases in myosin phosphorylation in Dictyostelium.
Cell 1985;43(1):307-14.
1985: Devreotes P N; Sherring J A
Kinetics and concentration dependence of reversible cAMP-induced modification of the surface cAMP receptor in Dictyostelium.
The Journal of biological chemistry 1985;260(10):6378-84.
1985: Klein P; Theibert A; Fontana D; Devreotes P N
Identification and cyclic AMP-induced modification of the cyclic AMP receptor in Dictyostelium discoideum.
The Journal of biological chemistry 1985;260(3):1757-64.
1985: Klein P; Fontana D; Knox B; Theibert A; Devreotes P
cAMP receptors controlling cell-cell interactions in the development of Dictyostelium.
Cold Spring Harbor symposia on quantitative biology 1985;50():787-99.
1984: Fontana D R; Devreotes P N
cAMP-stimulated adenylate cyclase activation in Dictyostelium discoideum is inhibited by agents acting at the cell surface.
Developmental biology 1984;106(1):76-82.
1984: Theibert A; Devreotes P N
Adenosine and its derivatives inhibit the cAMP signaling response in Dictyostelium discoideum.
Developmental biology 1984;106(1):166-73.
1984: Theibert A; Klein P; Devreotes P N
Specific photoaffinity labeling of the cAMP surface receptor in Dictyostelium discoideum.
The Journal of biological chemistry 1984;259(20):12318-21.
1983: Theibert A; Devreotes P N
Cyclic 3', 5'-AMP relay in Dictyostelium discoideum: adaptation is independent of activation of adenylate cyclase.
The Journal of cell biology 1983;97(1):173-7.
1983: Devreotes P N; Potel M J; MacKay S A
Quantitative analysis of cyclic AMP waves mediating aggregation in Dictyostelium discoideum.
Developmental biology 1983;96(2):405-15.
1983: Devreotes P N
The effect of folic acid on cAMP-elicited cAMP production in Dictyostelium discoideum.
Developmental biology 1983;95(1):154-62.
1981: Tomchik K J; Devreotes P N
Adenosine 3',5'-monophosphate waves in Dictyostelium discoideum: a demonstration by isotope dilution--fluorography.
Science (New York, N.Y.) 1981;212(4493):443-6.
1980: Dinauer M C; Steck T L; Devreotes P N
Cyclic 3',5'-AMP relay in Dictyostelium discoideum V. Adaptation of the cAMP signaling response during cAMP stimulation.
The Journal of cell biology 1980;86(2):554-61.
1980: Dinauer M C; Steck T L; Devreotes P N
Cyclic 3',5'-AMP relay in Dictyostelium discoideum IV. Recovery of the cAMP signaling response after adaptation to cAMP.
The Journal of cell biology 1980;86(2):545-53.
1980: Dinauer M C; MacKay S A; Devreotes P N
Cyclic 3',5'-AMP relay in Dictyostelium discoideum III. The relationship of cAMP synthesis and secretion during the cAMP signaling response.
The Journal of cell biology 1980;86(2):537-44.
1979: Devreotes P N; Steck T L
Cyclic 3',5' AMP relay in Dictyostelium discoideum. II. Requirements for the initiation and termination of the response.
The Journal of cell biology 1979;80(2):300-9.
1979: Devreotes P N; Derstine P L; Steck T L
Cyclic 3',5' AMP relay in Dictyostelium discoideum. I. A technique to monitor responses to controlled stimuli.
The Journal of cell biology 1979;80(2):291-9.
1979: Fambrough D M; Devreotes P N; Gardner J M; Card D J
The life history of acetylcholine receptors.
Progress in brain research 1979;49():325-34.
1978: Fambrough D M; Devreotes P N; Card D J; Gardner J; Tepperman K
Metabolism of acetylcholine receptors in skeletal muscle.
National Cancer Institute monograph 1978;(48):277-94.
1978: Fambrough D M; Devreotes P N
Newly synthesized acetylcholine receptors are located in the Golgi apparatus.
The Journal of cell biology 1978;76(1):237-44.
1977: Devreotes P N; Gardner J M; Fambrough D M
Kinetics of biosynthesis of acetylcholine receptor and subsequent incorporation into plasma membrane of cultured chick skeletal muscle.
Cell 1977;10(3):365-73.
1976: Devreotes P N; Fambrough D M
Synthesis of acetylcholine receptors by cultured chick myotubes and denervated mouse extensor digitorum longus muscles.
Proceedings of the National Academy of Sciences of the United States of America 1976;73(1):161-4.
1976: Devreotes P N; Fambrough D M
Turnover of acetylcholine receptors in skeletal muscle.
Cold Spring Harbor symposia on quantitative biology 1976;40():237-51.
1975: Devreotes P N; Fambrough D M
Acetylcholine receptor turnover in membranes of developing muscle fibers.
The Journal of cell biology 1975;65(2):335-58.

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