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Stephen Dewey

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David Alexoff; Stephen L Dewey; Paul Vaska; Srilalan Krishnamoorthy; Richard Ferrieri; Michael Schueller; David J Schlyer; Joanna S Fowler
PET imaging of thin objects: measuring the effects of positron range and partial-volume averaging in the leaf of Nicotiana tabacum.
Martine M Mirrione; Dorothy K Konomos; Iordanis Gravanis; Stephen L Dewey; Adriano Aguzzi; Frank L Heppner; Stella E Tsirka
Microglial ablation and lipopolysaccharide preconditioning affects pilocarpine-induced seizures in mice.
Konstantinos Pothakos; John K Robinson; Iordanis Gravanis; Douglas A Marsteller; Stephen L Dewey; Stella E Tsirka
Decreased serotonin levels associated with behavioral disinhibition in tissue plasminogen activator deficient (tPA-/-) mice.

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2011: David Alexoff; Stephen L Dewey; Paul Vaska; Srilalan Krishnamoorthy; Richard Ferrieri; Michael Schueller; David J Schlyer; Joanna S Fowler
PET imaging of thin objects: measuring the effects of positron range and partial-volume averaging in the leaf of Nicotiana tabacum.
Nuclear medicine and biology 2011;38(2):191-200.
2010: Martine M Mirrione; Dorothy K Konomos; Iordanis Gravanis; Stephen L Dewey; Adriano Aguzzi; Frank L Heppner; Stella E Tsirka
Microglial ablation and lipopolysaccharide preconditioning affects pilocarpine-induced seizures in mice.
Neurobiology of disease 2010;39(1):85-97.
2010: Konstantinos Pothakos; John K Robinson; Iordanis Gravanis; Douglas A Marsteller; Stephen L Dewey; Stella E Tsirka
Decreased serotonin levels associated with behavioral disinhibition in tissue plasminogen activator deficient (tPA-/-) mice.
Brain research 2010;1326():135-42.
2009: Jonathan D Brodie; Brady G Case; Emilia Figueroa; Stephen L Dewey; James A Robinson; Joseph A Wanderling; Eugene M Laska
Randomized, double-blind, placebo-controlled trial of vigabatrin for the treatment of cocaine dependence in Mexican parolees.
The American journal of psychiatry 2009;166(11):1269-77.
2009: Wynne K Schiffer; Courtney N B Liebling; Corinne Reiszel; Jacob M Hooker; Jonathan D Brodie; Stephen L Dewey
Cue-induced dopamine release predicts cocaine preference: positron emission tomography studies in freely moving rodents.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009;29(19):6176-85.
2008: Amy DeMarco; Reema M Dalal; Milan Kahanda; Uma Mullapudi; Jessica Pai; Crystie Hammel; Courtney N B Liebling; Vinal Patel; Jonathan D Brodie; Wynne K Schiffer; Stephen L Dewey; Stefanie D Aquilina
Subchronic racemic gamma vinyl-GABA produces weight loss in Sprague Dawley and Zucker fatty rats.
Synapse (New York, N.Y.) 2008;62(11):870-2.
2008: Xiao-Qing Peng; Xia Li; Jeremy G Gilbert; Arlene C Pak; Charles R Ashby; Jonathan D Brodie; Stephen L Dewey; Eliot L Gardner; Zheng-Xiong Xi
Gamma-vinyl GABA inhibits cocaine-triggered reinstatement of drug-seeking behavior in rats by a non-dopaminergic mechanism.
Drug and alcohol dependence 2008;97(3):216-25.
2008: Vinal D Patel; Dianne E Lee; David Alexoff; Stephen L Dewey; Wynne K Schiffer
Imaging dopamine release with Positron Emission Tomography (PET) and (11)C-raclopride in freely moving animals.
NeuroImage 2008;41(3):1051-66.
2008: Dianne E Lee; Jennifer Pai; Uma Mullapudui; David Alexoff; Richard Ferrieri; Stephen L Dewey
The effects of inhaled acetone on place conditioning in adolescent rats.
Pharmacology, biochemistry, and behavior 2008;89(1):101-5.
2007: Douglas A Marsteller; Nicole C Barbarich-Marsteller; Vinal D Patel; Stephen L Dewey
Brain metabolic changes following 4-week citalopram infusion: increased 18FDG uptake and gamma-amino butyric acid levels.
Synapse (New York, N.Y.) 2007;61(11):877-81.
2007: Martine M Mirrione; Wynne K Schiffer; Joanna S Fowler; David Alexoff; Stephen L Dewey; Stella E Tsirka
A novel approach for imaging brain-behavior relationships in mice reveals unexpected metabolic patterns during seizures in the absence of tissue plasminogen activator.
NeuroImage 2007;38(1):34-42.
2007: Wynne K Schiffer; Courtney N B Liebling; Vinal Patel; Stephen L Dewey
Targeting the treatment of drug abuse with molecular imaging.
Nuclear medicine and biology 2007;34(7):833-47.
2007: Joanna S Fowler; Carsten Kroll; Richard Ferrieri; David Alexoff; Jean Logan; Stephen L Dewey; Wynne K Schiffer; David Schlyer; Pauline Carter; Payton King; Colleen Shea; Youwen Xu; Lisa Muench; Helene Benveniste; Paul Vaska; Nora D Volkow
PET studies of d-methamphetamine pharmacokinetics in primates: comparison with l-methamphetamine and ( --)-cocaine.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2007;48(10):1724-32.
2007: Wynne K Schiffer; Martine M Mirrione; Stephen L Dewey
Optimizing experimental protocols for quantitative behavioral imaging with 18F-FDG in rodents.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2007;48(2):277-87.
2006: Wynne K Schiffer; Martine M Mirrione; Anat Biegon; David Alexoff; Vinal Patel; Stephen L Dewey
Serial microPET measures of the metabolic reaction to a microdialysis probe implant.
Journal of neuroscience methods 2006;155(2):272-84.
2006: Robert D Fechtner; Albert S Khouri; Emilia Figueroa; Marina Ramirez; Martha Federico; Stephen L Dewey; Jonathan D Brodie
Short-term treatment of cocaine and/or methamphetamine abuse with vigabatrin: ocular safety pilot results.
Archives of ophthalmology 2006;124(9):1257-62.
2006: Wynne K Schiffer; Dianne E Lee; David Alexoff; Richard Ferrieri; Jonathan D Brodie; Stephen L Dewey
Metabolic correlates of toluene abuse: decline and recovery of function in adolescent animals.
Psychopharmacology 2006;186(2):159-67.
2006: Wynne K Schiffer; Nora D Volkow; Joanna S Fowler; David Alexoff; Jean Logan; Stephen L Dewey
Therapeutic doses of amphetamine or methylphenidate differentially increase synaptic and extracellular dopamine.
Synapse (New York, N.Y.) 2006;59(4):243-51.
2006: Martine M Mirrione; Wynne K Schiffer; Mustafa Siddiq; Stephen L Dewey; Stella E Tsirka
PET imaging of glucose metabolism in a mouse model of temporal lobe epilepsy.
Synapse (New York, N.Y.) 2006;59(2):119-21.
2006: Douglas A Marsteller; Nicole C Barbarich-Marsteller; Joanna S Fowler; Wynne K Schiffer; David Alexoff; Daniel J Rubins; Stephen L Dewey
Reproducibility of intraperitoneal 2-deoxy-2-[18F]-fluoro-D-glucose cerebral uptake in rodents through time.
Nuclear medicine and biology 2006;33(1):71-9.
2005: Nicole C Barbarich-Marsteller; Douglas A Marsteller; David Alexoff; Joanna S Fowler; Stephen L Dewey
MicroPET imaging in an animal model of anorexia nervosa.
Synapse (New York, N.Y.) 2005;57(2):85-90.
2005: Wynne K Schiffer; David Alexoff; Colleen Shea; Jean Logan; Stephen L Dewey
Development of a simultaneous PET/microdialysis method to identify the optimal dose of 11C-raclopride for small animal imaging.
Journal of neuroscience methods 2005;144(1):25-34.
2005: Wynne K Schiffer; Dianne E Lee; Jonathan D Brodie; Stephen L Dewey
Imaging addiction with PET: is insight in sight?
Drug discovery today 2005;10(8):547-62.
2005: Jonathan D Brodie; Emilia Figueroa; Eugene M Laska; Stephen L Dewey
Safety and efficacy of gamma-vinyl GABA (GVG) for the treatment of methamphetamine and/or cocaine addiction.
Synapse (New York, N.Y.) 2005;55(2):122-5.
2004: Dianne E Lee; Wynne K Schiffer; Stephen L Dewey
Gamma-vinyl GABA (vigabatrin) blocks the expression of toluene-induced conditioned place preference (CPP).
Synapse (New York, N.Y.) 2004;54(3):183-5.
2003: Jonathan D Brodie; Emilia Figueroa; Stephen L Dewey
Treating cocaine addiction: from preclinical to clinical trial experience with gamma-vinyl GABA.
Synapse (New York, N.Y.) 2003;50(3):261-5.
2003: Wynne K Schiffer; Jean Logan; Stephen L Dewey
Positron emission tomography studies of potential mechanisms underlying phencyclidine-induced alterations in striatal dopamine.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2003;28(12):2192-8.
2003: Wynne K Schiffer; Douglas A Marsteller; Stephen L Dewey
Sub-chronic low dose gamma-vinyl GABA (vigabatrin) inhibits cocaine-induced increases in nucleus accumbens dopamine.
Psychopharmacology 2003;168(3):339-43.
2003: Wynne K Schiffer; Manijeh Azmoodeh; Madina R Gerasimov; Nora D Volkow; Joanna S Fowler; Stephen L Dewey
Selegiline potentiates cocaine-induced increases in rodent nucleus accumbens dopamine.
Synapse (New York, N.Y.) 2003;48(1):35-8.
2002: Eliot L Gardner; Wynne K Schiffer; Bryan A Horan; David A Highfield; Stephen L Dewey; Jonathan D Brodie; Charles R Ashby
Gamma-vinyl GABA, an irreversible inhibitor of GABA transaminase, alters the acquisition and expression of cocaine-induced sensitization in male rats.
Synapse (New York, N.Y.) 2002;46(4):240-50.
2002: Douglas A Marsteller; Madina R Gerasimov; Wynne K Schiffer; Justin M Geiger; Channing R Barnett; Jana Schaich Borg; Sabria Scott; Jill Ceccarelli; Nora D Volkow; Patricia E Molina; David Alexoff; Stephen L Dewey
Acute handling stress modulates methylphenidate-induced catecholamine overflow in the medial prefrontal cortex.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2002;27(2):163-70.
2002: Madina R Gerasimov; Jean Logan; Richard Ferrieri; Ryan D Muller; David Alexoff; Stephen L Dewey
Effect of vehicle on brain uptake of [11C]toluene.
Nuclear medicine and biology 2002;29(5):607-12.
2002: Charles R Ashby; Mousumi Paul; Eliot L Gardner; Madina R Gerasimov; Stephen L Dewey; Ian C Lennon; Stephen J C Taylor
Systemic administration of 1R,4S-4-amino-cyclopent-2-ene-carboxylic acid, a reversible inhibitor of GABA transaminase, blocks expression of conditioned place preference to cocaine and nicotine in rats.
Synapse (New York, N.Y.) 2002;44(2):61-3.
2002: Madina R Gerasimov; Richard Ferrieri; Wynne K Schiffer; Jean Logan; S John Gatley; Andrew N Gifford; David A Alexoff; Douglas A Marsteller; Colleen Shea; Victor Garza; Pauline Carter; Payton King; Charles R Ashby; SA Vitkun; Stephen L Dewey
Study of brain uptake and biodistribution of [11C]toluene in non-human primates and mice.
Life sciences 2002;70(23):2811-28.
2002: Madina R Gerasimov; Wynne K Schiffer; Douglas Marstellar; Richard Ferrieri; David Alexoff; Stephen L Dewey
Toluene inhalation produces regionally specific changes in extracellular dopamine.
Drug and alcohol dependence 2002;65(3):243-51.
2001: Wynne K Schiffer; Madina R Gerasimov; Douglas A Marsteller; J Geiger; C Barnett; David Alexoff; Stephen L Dewey
Topiramate selectively attenuates nicotine-induced increases in monoamine release.
Synapse (New York, N.Y.) 2001;42(3):196-8.
2001: Wynne K Schiffer; Madina R Gerasimov; L Hofmann; Douglas A Marsteller; Charles R Ashby; Jonathan D Brodie; David Alexoff; Stephen L Dewey
Gamma vinyl-GABA differentially modulates NMDA antagonist-induced increases in mesocortical versus mesolimbic DA transmission.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2001;25(5):704-12.
2001: M Paul; Stephen L Dewey; Eliot L Gardner; Jonathan D Brodie; Charles R Ashby
Gamma-vinyl GABA (GVG) blocks expression of the conditioned place preference response to heroin in rats.
Synapse (New York, N.Y.) 2001;41(3):219-20.
2001: Bryan A Horan; Eliot L Gardner; Stephen L Dewey; Jonathan D Brodie; Charles R Ashby
The selective sigma(1) receptor agonist, 1-(3,4-dimethoxyphenethyl)-4-(phenylpropyl)piperazine (SA4503), blocks the acquisition of the conditioned place preference response to (-)-nicotine in rats.
European journal of pharmacology 2001;426(1-2):R1-2.
2001: Madina R Gerasimov; Wynne K Schiffer; Eliot L Gardner; Douglas A Marsteller; Ian C Lennon; Stephen J C Taylor; Jonathan D Brodie; Charles R Ashby; Stephen L Dewey
GABAergic blockade of cocaine-associated cue-induced increases in nucleus accumbens dopamine.
European journal of pharmacology 2001;414(2-3):205-9.
2001: Jean Logan; Joanna S Fowler; Stephen L Dewey; Nora D Volkow; S John Gatley
A consideration of the dopamine D2 receptor monomer-dimer equilibrium and the anomalous binding properties of the dopamine D2 receptor ligand, N-methyl spiperone.
Journal of neural transmission (Vienna, Austria : 1996) 2001;108(3):279-86.
2000: Madina R Gerasimov; M Franceschi; Nora D Volkow; O Rice; Wynne K Schiffer; Stephen L Dewey
Synergistic interactions between nicotine and cocaine or methylphenidate depend on the dose of dopamine transporter inhibitor.
Synapse (New York, N.Y.) 2000;38(4):432-7.
2000: Madina R Gerasimov; M Franceschi; Nora D Volkow; Andrew N Gifford; S John Gatley; Douglas A Marsteller; Patricia E Molina; Stephen L Dewey
Comparison between intraperitoneal and oral methylphenidate administration: A microdialysis and locomotor activity study.
The Journal of pharmacology and experimental therapeutics 2000;295(1):51-7.
2000: Madina R Gerasimov; Wynne K Schiffer; Jonathan D Brodie; Ian C Lennon; Stephen J C Taylor; Stephen L Dewey
gamma-aminobutyric acid mimetic drugs differentially inhibit the dopaminergic response to cocaine.
European journal of pharmacology 2000;395(2):129-35.
2000: Wynne K Schiffer; Madina R Gerasimov; R A Bermel; Jonathan D Brodie; Stephen L Dewey
Stereoselective inhibition of dopaminergic activity by gamma vinyl-GABA following a nicotine or cocaine challenge: a PET/microdialysis study.
Life sciences 2000;66(13):PL169-73.
1999: Madina R Gerasimov; Charles R Ashby; Eliot L Gardner; Mark J Mills; Jonathan D Brodie; Stephen L Dewey
Gamma-vinyl GABA inhibits methamphetamine, heroin, or ethanol-induced increases in nucleus accumbens dopamine.
Synapse (New York, N.Y.) 1999;34(1):11-9.
1999: Madina R Gerasimov; Stephen L Dewey
Gamma-vinyl gamma-aminobutyric acid attenuates the synergistic elevations of nucleus accumbens dopamine produced by a cocaine/heroin (speedball) challenge.
European journal of pharmacology 1999;380(1):1-4.
1999: S John Gatley; Nora D Volkow; Andrew N Gifford; Joanna S Fowler; Stephen L Dewey; Yu-Shin Ding; Jean Logan
Dopamine-transporter occupancy after intravenous doses of cocaine and methylphenidate in mice and humans.
Psychopharmacology 1999;146(1):93-100.
1999: Joanna S Fowler; Nora D Volkow; Yu-Shin Ding; Gene-Jack Wang; Stephen L Dewey; MW Fischman; RW Foltin; Robert Hitzemann
Positron emission tomography studies of dopamine-enhancing drugs.
Journal of clinical pharmacology 1999;Suppl():13S-16S.
1999: S A Kushner; Stephen L Dewey; Conan Kornetsky
The irreversible gamma-aminobutyric acid (GABA) transaminase inhibitor gamma-vinyl-GABA blocks cocaine self-administration in rats.
The Journal of pharmacology and experimental therapeutics 1999;290(2):797-802.
1999: Joanna S Fowler; Nora D Volkow; Gene-Jack Wang; Yu-Shin Ding; Stephen L Dewey
PET and drug research and development.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1999;40(7):1154-63.
1999: Charles R Ashby; R Rohatgi; J Ngosuwan; T Borda; Madina R Gerasimov; AE Morgan; S Kushner; Jonathan D Brodie; Stephen L Dewey
Implication of the GABA(B) receptor in gamma vinyl-GABA's inhibition of cocaine-induced increases in nucleus accumbens dopamine.
Synapse (New York, N.Y.) 1999;31(2):151-3.
1999: Patricia E Molina; N Ahmed; M Ajmal; Stephen L Dewey; Nora D Volkow; Joanna S Fowler; Naji N Abumrad
Co-administration of gamma-vinyl GABA and cocaine: preclinical assessment of safety.
Life sciences 1999;65(11):1175-82.
1999: Stephen L Dewey; Jonathan D Brodie; Madina R Gerasimov; Bryan A Horan; Eliot L Gardner; Charles R Ashby
A pharmacologic strategy for the treatment of nicotine addiction.
Synapse (New York, N.Y.) 1999;31(1):76-86.
1999: Nora D Volkow; Joanna S Fowler; S John Gatley; Stephen L Dewey; Gene-Jack Wang; Jean Logan; Yu-Shin Ding; Dinko Franceschi; Andrew N Gifford; A Morgan; Naomi Pappas; Payton King
Comparable changes in synaptic dopamine induced by methylphenidate and by cocaine in the baboon brain.
Synapse (New York, N.Y.) 1999;31(1):59-66.
1999: Nora D Volkow; Gene-Jack Wang; Joanna S Fowler; S John Gatley; Jean Logan; Yu-Shin Ding; Stephen L Dewey; Robert Hitzemann; Andrew N Gifford; Naomi Pappas
Blockade of striatal dopamine transporters by intravenous methylphenidate is not sufficient to induce self-reports of "high".
The Journal of pharmacology and experimental therapeutics 1999;288(1):14-20.
1998: CS Chaurasia; CE Chen; J Rubin; Stephen L Dewey
Effects of tamoxifen on striatal dopamine and 5-hydroxytryptamine release in freely moving male rats: an in-vivo microdialysis investigation.
The Journal of pharmacy and pharmacology 1998;50(12):1377-85.
1998: Stephen L Dewey; AE Morgan; Charles R Ashby; Bryan A Horan; S A Kushner; Jean Logan; Nora D Volkow; Joanna S Fowler; Eliot L Gardner; Jonathan D Brodie
A novel strategy for the treatment of cocaine addiction.
Synapse (New York, N.Y.) 1998;30(2):119-29.
1998: AE Morgan; Jonathan D Brodie; Stephen L Dewey
What are we measuring with PET?
The quarterly journal of nuclear medicine : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR) 1998;42(3):151-7.
1998: S John Gatley; Yu-Shin Ding; D Brady; Andrew N Gifford; Stephen L Dewey; F I Carroll; Joanna S Fowler; Nora D Volkow
In vitro and ex vivo autoradiographic studies of nicotinic acetylcholine receptors using [18F]fluoronochloroepibatidine in rodent and human brain.
Nuclear medicine and biology 1998;25(5):449-54.
1998: Ralf Schlösser; Michael Hutchinson; Seth S Joseffer; Henry Rusinek; A Saarimaki; J Stevenson; Stephen L Dewey; Jonathan D Brodie
Functional magnetic resonance imaging of human brain activity in a verbal fluency task.
Journal of neurology, neurosurgery, and psychiatry 1998;64(4):492-8.
1998: E J Bartlett; Jonathan D Brodie; P Simkowitz; Ralf Schlösser; Stephen L Dewey; Jean-Pierre Lindenmayer; Henry Rusinek; Adam Wolkin; Robert Cancro; Wynne K Schiffer
Effect of a haloperidol challenge on regional brain metabolism in neuroleptic-responsive and nonresponsive schizophrenic patients.
The American journal of psychiatry 1998;155(3):337-43.
1998: S John Gatley; R Lan; Nora D Volkow; Naomi Pappas; Payton King; Christopher T Wong; Andrew N Gifford; Bea Pyatt; Stephen L Dewey; Alexandros Makriyannis
Imaging the brain marijuana receptor: development of a radioligand that binds to cannabinoid CB1 receptors in vivo.
Journal of neurochemistry 1998;70(1):417-23.
1998: Ralf Schlösser; Jonathan D Brodie; Stephen L Dewey; David Alexoff; Gene-Jack Wang; Joanna S Fowler; Nora D Volkow; Jean Logan; AP Wolf
Long-term stability of neurotransmitter activity investigated with 11C-raclopride PET.
Synapse (New York, N.Y.) 1998;28(1):66-70.
1998: AE Morgan; Stephen L Dewey
Effects of pharmacologic increases in brain GABA levels on cocaine-induced changes in extracellular dopamine.
Synapse (New York, N.Y.) 1998;28(1):60-5.
1998: Gwenn S Smith; Ralf Schlösser; Jonathan D Brodie; Stephen L Dewey; Jean Logan; SA Vitkun; P Simkowitz; A Hurley; T Cooper; Nora D Volkow; Robert Cancro
Glutamate modulation of dopamine measured in vivo with positron emission tomography (PET) and 11C-raclopride in normal human subjects.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 1998;18(1):18-25.
1997: S A Kushner; Stephen L Dewey; Conan Kornetsky
Gamma-vinyl GABA attenuates cocaine-induced lowering of brain stimulation reward thresholds.
Psychopharmacology 1997;133(4):383-8.
1997: AE Morgan; S P Porter; F A Clarkson; Nora D Volkow; Joanna S Fowler; Stephen L Dewey
Direct approach for attenuating cocaine's effects on extracellular dopamine: targeting the dopamine transporter.
Synapse (New York, N.Y.) 1997;26(4):423-7.
1997: AE Morgan; Bryan A Horan; Stephen L Dewey; Charles R Ashby
Repeated administration of 3,4-methylenedioxymethamphetamine augments cocaine's action on dopamine in the nucleus accumbens: a microdialysis study.
European journal of pharmacology 1997;331(1):R1-3.
1997: Yu-Shin Ding; Joanna S Fowler; Nora D Volkow; Stephen L Dewey; Gene-Jack Wang; Jean Logan; S John Gatley; Naomi Pappas
Chiral drugs: comparison of the pharmacokinetics of [11C]d-threo and L-threo-methylphenidate in the human and baboon brain.
Psychopharmacology 1997;131(1):71-8.
1997: Nora D Volkow; Gene-Jack Wang; Joanna S Fowler; Jean Logan; S John Gatley; Robert Hitzemann; A D Chen; Stephen L Dewey; Naomi Pappas
Decreased striatal dopaminergic responsiveness in detoxified cocaine-dependent subjects.
Nature 1997;386(6627):830-3.
1997: Stephen L Dewey; CS Chaurasia; CE Chen; Nora D Volkow; F A Clarkson; S P Porter; R M Straughter-Moore; David Alexoff; D Tedeschi; N B Russo; Joanna S Fowler; Jonathan D Brodie
GABAergic attenuation of cocaine-induced dopamine release and locomotor activity.
Synapse (New York, N.Y.) 1997;25(4):393-8.
1997: Gwenn S Smith; Stephen L Dewey; Jonathan D Brodie; Jean Logan; SA Vitkun; P Simkowitz; Ralf Schlösser; David A Alexoff; A Hurley; T Cooper; Nora D Volkow
Serotonergic modulation of dopamine measured with [11C]raclopride and PET in normal human subjects.
The American journal of psychiatry 1997;154(4):490-6.
1997: C Y Shiue; S Vallabhahosula; AP Wolf; Stephen L Dewey; Joanna S Fowler; David Schlyer; C D Arnett; Y G Zhou
Carbon-11 labelled ketamine-synthesis, distribution in mice and PET studies in baboons.
Nuclear medicine and biology 1997;24(2):145-50.
1996: Yu-Shin Ding; S John Gatley; Joanna S Fowler; Nora D Volkow; D Aggarwal; Jean Logan; Stephen L Dewey; F Liang; F I Carroll; Michael J Kuhar
Mapping nicotinic acetylcholine receptors with PET.
Synapse (New York, N.Y.) 1996;24(4):403-7.
1996: Ralf Schlösser; P Simkowitz; E J Bartlett; Adam Wolkin; Gwenn S Smith; Stephen L Dewey; Jonathan D Brodie
The study of neurotransmitter interactions using positron emission tomography and functional coupling.
Clinical neuropharmacology 1996;19(5):371-89.
1996: Nora D Volkow; Gene-Jack Wang; Joanna S Fowler; S John Gatley; Yu-Shin Ding; Jean Logan; Stephen L Dewey; Robert Hitzemann; J Lieberman
Relationship between psychostimulant-induced "high" and dopamine transporter occupancy.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(19):10388-92.
1996: Nora D Volkow; Joanna S Fowler; S John Gatley; Jean Logan; Gene-Jack Wang; Yu-Shin Ding; Stephen L Dewey
PET evaluation of the dopamine system of the human brain.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1996;37(7):1242-56.
1996: Igor I Galynker; David Schlyer; Stephen L Dewey; Joanna S Fowler; Jean Logan; S John Gatley; Robert R MacGregor; R A Ferrieri; M J Holland; Jonathan D Brodie; E Simon; AP Wolf
Opioid receptor imaging and displacement studies with [6-O-[11C] methyl]buprenorphine in baboon brain.
Nuclear medicine and biology 1996;23(3):325-31.
1996: E J Bartlett; Jonathan D Brodie; P Simkowitz; Stephen L Dewey; Henry Rusinek; Nora D Volkow; AP Wolf; Gwenn S Smith; Adam Wolkin; Robert Cancro
Time-dependent effects of a haloperidol challenge on energy metabolism in the normal human brain.
Psychiatry research 1996;60(2-3):91-9.
1996: K A Yousef; Joanna S Fowler; Nora D Volkow; Stephen L Dewey; Colleen Shea; David Schlyer; S John Gatley; Jean Logan; AP Wolf
[18F]haloperidol binding in baboon brain in vivo.
Nuclear medicine and biology 1996;23(1):47-52.
1996: S John Gatley; S M Meehan; R Chen; D F Pan; M D Schechter; Stephen L Dewey
Place preference and microdialysis studies with two derivatives of methylphenidate.
Life sciences 1996;58(24):PL345-52.
1995: Nora D Volkow; Joanna S Fowler; Jean Logan; S John Gatley; Stephen L Dewey; Robert R MacGregor; David Schlyer; Naomi Pappas; Payton King; Gene-Jack Wang
Carbon-11-cocaine binding compared at subpharmacological and pharmacological doses: a PET study.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1995;36(7):1289-97.
1995: S John Gatley; Nora D Volkow; Joanna S Fowler; Stephen L Dewey; Jean Logan
Sensitivity of striatal [11C]cocaine binding to decreases in synaptic dopamine.
Synapse (New York, N.Y.) 1995;20(2):137-44.
1995: Nora D Volkow; S John Gatley; Joanna S Fowler; R Chen; Jean Logan; Stephen L Dewey; Yu-Shin Ding; Naomi Pappas; Payton King; Robert R MacGregor
Long-lasting inhibition of in vivo cocaine binding to dopamine transporters by 3 beta-(4-iodophenyl)tropane-2-carboxylic acid methyl ester: RTI-55 or beta CIT.
Synapse (New York, N.Y.) 1995;19(3):206-11.
1995: Stephen L Dewey; Gwenn S Smith; Jean Logan; David Alexoff; Yu-Shin Ding; Payton King; Naomi Pappas; Jonathan D Brodie; Charles R Ashby
Serotonergic modulation of striatal dopamine measured with positron emission tomography (PET) and in vivo microdialysis.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1995;15(1 Pt 2):821-9.
1994: Jean Logan; Nora D Volkow; Joanna S Fowler; Gene-Jack Wang; Stephen L Dewey; R MacGregor; David Schlyer; S John Gatley; Naomi Pappas; Payton King
Effects of blood flow on [11C]raclopride binding in the brain: model simulations and kinetic analysis of PET data.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1994;14(6):995-1010.
1994: D Pan; S John Gatley; Stephen L Dewey; R Chen; D A Alexoff; Yu-Shin Ding; Joanna S Fowler
Binding of bromine-substituted analogs of methylphenidate to monoamine transporters.
European journal of pharmacology 1994;264(2):177-82.
1994: Yu-Shin Ding; Joanna S Fowler; Nora D Volkow; S John Gatley; Jean Logan; Stephen L Dewey; David Alexoff; E Fazzini; AP Wolf
Pharmacokinetics and in vivo specificity of [11C]dl-threo-methylphenidate for the presynaptic dopaminergic neuron.
Synapse (New York, N.Y.) 1994;18(2):152-60.
1994: E J Bartlett; Jonathan D Brodie; P Simkowitz; Stephen L Dewey; Henry Rusinek; AP Wolf; Joanna S Fowler; Nora D Volkow; Gwenn S Smith; Adam Wolkin
Effects of haloperidol challenge on regional cerebral glucose utilization in normal human subjects.
The American journal of psychiatry 1994;151(5):681-6.
1994: Joanna S Fowler; Yu-Shin Ding; Nora D Volkow; T Martin; Robert R MacGregor; Stephen L Dewey; Payton King; Naomi Pappas; David Alexoff; Colleen Shea
PET studies of cocaine inhibition of myocardial norepinephrine uptake.
Synapse (New York, N.Y.) 1994;16(4):312-7.
1994: S John Gatley; D W Yu; Joanna S Fowler; Robert R MacGregor; David Schlyer; Stephen L Dewey; AP Wolf; T Martin; C E Shea; Nora D Volkow
Studies with differentially labeled [11C]cocaine, [11C]norcocaine, [11C]benzoylecgonine, and [11C]- and 4'-[18F]fluorococaine to probe the extent to which [11C]cocaine metabolites contribute to PET images of the baboon brain.
Journal of neurochemistry 1994;62(3):1154-62.
1994: W Guenther; Jonathan D Brodie; E J Bartlett; Stephen L Dewey; Fritz Henn; Nora D Volkow; Kenneth R Alper; Adam Wolkin; Robert Cancro; AP Wolf
Diminished cerebral metabolic response to motor stimulation in schizophrenics: a PET study.
European archives of psychiatry and clinical neuroscience 1994;244(3):115-25.
1993: Stephen L Dewey; Gwenn S Smith; Jean Logan; Jonathan D Brodie; P Simkowitz; Robert R MacGregor; Joanna S Fowler; Nora D Volkow; AP Wolf
Effects of central cholinergic blockade on striatal dopamine release measured with positron emission tomography in normal human subjects.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(24):11816-20.
1993: Stephen L Dewey; Gwenn S Smith; Jean Logan; Jonathan D Brodie
Modulation of central cholinergic activity by GABA and serotonin: PET studies with 11C-benztropine in primates.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 1993;8(4):371-6.
1993: Nora D Volkow; Joanna S Fowler; Gene-Jack Wang; Robert Hitzemann; Jean Logan; David Schlyer; Stephen L Dewey; AP Wolf
Decreased dopamine D2 receptor availability is associated with reduced frontal metabolism in cocaine abusers.
Synapse (New York, N.Y.) 1993;14(2):169-77.
1993: Stephen L Dewey; Gwenn S Smith; Jean Logan; Jonathan D Brodie; Joanna S Fowler; AP Wolf
Striatal binding of the PET ligand 11C-raclopride is altered by drugs that modify synaptic dopamine levels.
Synapse (New York, N.Y.) 1993;13(4):350-6.
1993: Yu-Shin Ding; Joanna S Fowler; Stephen L Dewey; Jean Logan; David Schlyer; S John Gatley; Nora D Volkow; P T King; AP Wolf
Comparison of high specific activity (-) and (+)-6-[18F]fluoronorepinephrine and 6-[18F]fluorodopamine in baboons: heart uptake, metabolism and the effect of desipramine.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1993;34(4):619-29.
1993: Nora D Volkow; Joanna S Fowler; Gene-Jack Wang; Stephen L Dewey; David Schlyer; R MacGregor; Jean Logan; David Alexoff; Colleen Shea; Robert Hitzemann
Reproducibility of repeated measures of carbon-11-raclopride binding in the human brain.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1993;34(4):609-13.
1993: Nora D Volkow; Gene-Jack Wang; Robert Hitzemann; Joanna S Fowler; AP Wolf; Naomi Pappas; A Biegon; Stephen L Dewey
Decreased cerebral response to inhibitory neurotransmission in alcoholics.
The American journal of psychiatry 1993;150(3):417-22.
1993: Yu-Shin Ding; Joanna S Fowler; Stephen L Dewey; AP Wolf; Jean Logan; S John Gatley; Nora D Volkow; Colleen Shea; D P Taylor
Synthesis and PET studies of fluorine-18-BMY 14802: a potential antipsychotic drug.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1993;34(2):246-54.
1992: Joanna S Fowler; Nora D Volkow; Robert R MacGregor; Jean Logan; Stephen L Dewey; S John Gatley; AP Wolf
Comparative PET studies of the kinetics and distribution of cocaine and cocaethylene in baboon brain.
Synapse (New York, N.Y.) 1992;12(3):220-7.
1992: Stephen L Dewey; Gwenn S Smith; Jean Logan; Jonathan D Brodie; D W Yu; R A Ferrieri; P T King; Robert R MacGregor; T P Martin; AP Wolf
GABAergic inhibition of endogenous dopamine release measured in vivo with 11C-raclopride and positron emission tomography.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1992;12(10):3773-80.
1992: Nora D Volkow; Robert Hitzemann; Gene-Jack Wang; Joanna S Fowler; G Burr; K Pascani; Stephen L Dewey; AP Wolf
Decreased brain metabolism in neurologically intact healthy alcoholics.
The American journal of psychiatry 1992;149(8):1016-22.
1992: Nora D Volkow; Robert Hitzemann; Gene-Jack Wang; Joanna S Fowler; AP Wolf; Stephen L Dewey; L Handlesman
Long-term frontal brain metabolic changes in cocaine abusers.
Synapse (New York, N.Y.) 1992;11(3):184-90.
1992: D W Yu; S John Gatley; AP Wolf; Robert R MacGregor; Stephen L Dewey; Joanna S Fowler; David Schlyer
Synthesis of carbon-11 labeled iodinated cocaine derivatives and their distribution in baboon brain measured using positron emission tomography.
Journal of medicinal chemistry 1992;35(12):2178-83.
1992: David Schlyer; Nora D Volkow; Joanna S Fowler; AP Wolf; Chyng-Yann Shiue; Stephen L Dewey; B Bendriem; Jean Logan; R Raulli; Robert Hitzemann
Regional distribution and kinetics of haloperidol binding in human brain: a PET study with [18F]haloperidol.
Synapse (New York, N.Y.) 1992;11(1):10-9.
1992: Nora D Volkow; Joanna S Fowler; AP Wolf; Gene-Jack Wang; Jean Logan; R MacGregor; Stephen L Dewey; David Schlyer; Robert Hitzemann
Distribution and kinetics of carbon-11-cocaine in the human body measured with PET.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1992;33(4):521-5.
1991: Jean Logan; Stephen L Dewey; AP Wolf; Joanna S Fowler; Jonathan D Brodie; B Angrist; Nora D Volkow; S John Gatley
Effects of endogenous dopamine on measures of [18F]N-methylspiroperidol binding in the basal ganglia: comparison of simulations and experimental results from PET studies in baboons.
Synapse (New York, N.Y.) 1991;9(3):195-207.
1991: Nora D Volkow; Joanna S Fowler; AP Wolf; Robert Hitzemann; Stephen L Dewey; B Bendriem; R Alpert; A Hoff
Changes in brain glucose metabolism in cocaine dependence and withdrawal.
The American journal of psychiatry 1991;148(5):621-6.
1991: Stephen L Dewey; Jean Logan; AP Wolf; Jonathan D Brodie; B Angrist; Joanna S Fowler; Nora D Volkow
Amphetamine induced decreases in (18F)-N-methylspiroperidol binding in the baboon brain using positron emission tomography (PET).
Synapse (New York, N.Y.) 1991;7(4):324-7.
1991: Yu-Shin Ding; Joanna S Fowler; S John Gatley; Stephen L Dewey; AP Wolf; David Schlyer
Synthesis of high specific activity 6-[18F]fluorodopamine for positron emission tomography studies of sympathetic nervous tissue.
Journal of medicinal chemistry 1991;34(2):861-3.
1991: Yu-Shin Ding; Joanna S Fowler; S John Gatley; Stephen L Dewey; AP Wolf
Synthesis of high specific activity (+)- and (-)-6-[18F]fluoronorepinephrine via the nucleophilic aromatic substitution reaction.
Journal of medicinal chemistry 1991;34(2):767-71.
1991: Chyng-Yann Shiue; L Q Bai; R R Teng; C D Arnett; Stephen L Dewey; AP Wolf; D W McPherson; Joanna S Fowler; Jean Logan; M J Holland
A comparison of the brain uptake of N-(cyclopropyl[11C]methyl)norbuprenorphine ([11C]buprenorphine) and N-(cyclopropyl[11C]methyl)nordiprenorphine ([11C]diprenorphine) in baboon using PET.
International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology 1991;18(3):281-8.
1991: Alain Plenevaux; Joanna S Fowler; Stephen L Dewey; AP Wolf; M Guillaume
The synthesis of no-carrier-added DL-4-[18F]fluorodeprenyl via the nucleophilic aromatic substitution reaction.
International journal of radiation applications and instrumentation. Part A, Applied radiation and isotopes 1991;42(2):121-7.
1990: Stephen L Dewey; Nora D Volkow; Jean Logan; Robert R MacGregor; Joanna S Fowler; David Schlyer; B Bendriem
Age-related decreases in muscarinic cholinergic receptor binding in the human brain measured with positron emission tomography (PET).
Journal of neuroscience research 1990;27(4):569-75.
1990: Jean Logan; Joanna S Fowler; Nora D Volkow; AP Wolf; Stephen L Dewey; David Schlyer; Robert R MacGregor; Robert Hitzemann; B Bendriem; S John Gatley
Graphical analysis of reversible radioligand binding from time-activity measurements applied to [N-11C-methyl]-(-)-cocaine PET studies in human subjects.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1990;10(5):740-7.
1990: Alain Plenevaux; Stephen L Dewey; Joanna S Fowler; M Guillaume; AP Wolf
Synthesis of (R)-(-)- and (S)-(+)-4-fluorodeprenyl and (R)-(-)- and (S)-(+)-[N-11C-methyl]-4-fluorodeprenyl and positron emission tomography studies in baboon brain.
Journal of medicinal chemistry 1990;33(7):2015-9.
1990: Nora D Volkow; Joanna S Fowler; AP Wolf; David Schlyer; Chyng-Yann Shiue; R Alpert; Stephen L Dewey; Jean Logan; B Bendriem; D Christman
Effects of chronic cocaine abuse on postsynaptic dopamine receptors.
The American journal of psychiatry 1990;147(6):719-24.
1990: Nora D Volkow; Robert Hitzemann; AP Wolf; Jean Logan; Joanna S Fowler; D Christman; Stephen L Dewey; David Schlyer; G Burr; SA Vitkun
Acute effects of ethanol on regional brain glucose metabolism and transport.
Psychiatry research 1990;35(1):39-48.
1990: S John Gatley; Robert R MacGregor; Joanna S Fowler; AP Wolf; Stephen L Dewey; David Schlyer
Rapid stereoselective hydrolysis of (+)-cocaine in baboon plasma prevents its uptake in the brain: implications for behavioral studies.
Journal of neurochemistry 1990;54(2):720-3.
1990: Stephen L Dewey; Robert R MacGregor; Jonathan D Brodie; B Bendriem; P T King; Nora D Volkow; David Schlyer; Joanna S Fowler; AP Wolf; S John Gatley
Mapping muscarinic receptors in human and baboon brain using [N-11C-methyl]-benztropine.
Synapse (New York, N.Y.) 1990;5(3):213-23.
1990: L Q Bai; R R Teng; Chyng-Yann Shiue; AP Wolf; Stephen L Dewey; M J Holland; E J Simon
No-carrier-added (NCA) N-(3-[18F]fluoropropyl)-N-norbuprenorphine and N-(3-[18F]fluoropropyl)-N-nordiprenorphine--synthesis, anatomical distribution in mice and rats, and tomographic studies in a baboon.
International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology 1990;17(2):217-27.
1990: R R Teng; L Q Bai; Chyng-Yann Shiue; Stephen L Dewey; C D Arnett; AP Wolf; Robert Hitzemann
The utility of 1-[18F]fluoro-3-iodopropane for the synthesis of certain dopamine D-1 and benzodiazepine receptor radioligands.
International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology 1990;17(8):811-7.
1990: Stephen L Dewey; Jonathan D Brodie; Joanna S Fowler; Robert R MacGregor; David Schlyer; P T King; David Alexoff; Nora D Volkow; Chyng-Yann Shiue; AP Wolf
Positron emission tomography (PET) studies of dopaminergic/cholinergic interactions in the baboon brain.
Synapse (New York, N.Y.) 1990;6(4):321-7.
1989: Joanna S Fowler; Nora D Volkow; AP Wolf; Stephen L Dewey; David Schlyer; Robert R MacGregor; Robert Hitzemann; Jean Logan; B Bendriem; S John Gatley
Mapping cocaine binding sites in human and baboon brain in vivo.
Synapse (New York, N.Y.) 1989;4(4):371-7.
1988: Joanna S Fowler; AP Wolf; Robert R MacGregor; Stephen L Dewey; Jean Logan; David Schlyer; B Langstrom
Mechanistic positron emission tomography studies: demonstration of a deuterium isotope effect in the monoamine oxidase-catalyzed binding of [11C]L-deprenyl in living baboon brain.
Journal of neurochemistry 1988;51(5):1524-34.
1987: Joanna S Fowler; R R MacGregor; AP Wolf; C D Arnett; Stephen L Dewey; David Schlyer; D Christman; Jean Logan; M Smith; H Sachs
Mapping human brain monoamine oxidase A and B with 11C-labeled suicide inactivators and PET.
Science (New York, N.Y.) 1987;235(4787):481-5.