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Sharmistha Dey

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Kamaldeep Gill; Prasida Holla; Vaishali Kapoor; Rahul Kumar; Bidhu K Mohanti; Lokesh Nigam; Abhay K Singh; Naidu Subbarao; Savita Yadav; Satya N Das; Sharmistha Dey
Development of peptide inhibitor as a therapeutic agent against head and neck squamous cell carcinoma (HNSCC) targeting p38alpha MAP kinase.
Biswajit Mishra; Ishan K Patro; Abhay K Singh; Kusum Singh; Immaculata Xess; Amit Dinda; Kamaldeep Gill; Arti Kapil; Geeta Devi Leishangthem; Swagata Das; Sharmistha Dey
A novel antimicrobial peptide derived from modified N-terminal domain of bovine lactoferrin: design, synthesis, activity against multidrug-resistant bacteria and Candida.
Rahul Kumar; Prakash K Sharma; Abhay K Singh; Manjari Tripathi; Prasun Chaterjee; Aparajit B Dey; Kamaldeep Gill; Abhishek Gupta; Sharmistha Dey
Sirtuin1: a promising serum protein marker for early detection of Alzheimer's disease.

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All Publications

2013: Kamaldeep Gill; Prasida Holla; Vaishali Kapoor; Rahul Kumar; Bidhu K Mohanti; Lokesh Nigam; Abhay K Singh; Naidu Subbarao; Savita Yadav; Satya N Das; Sharmistha Dey
Development of peptide inhibitor as a therapeutic agent against head and neck squamous cell carcinoma (HNSCC) targeting p38alpha MAP kinase.
Biochimica et biophysica acta 2013;1830(3):2763-9.
2013: Biswajit Mishra; Ishan K Patro; Abhay K Singh; Kusum Singh; Immaculata Xess; Amit Dinda; Kamaldeep Gill; Arti Kapil; Geeta Devi Leishangthem; Swagata Das; Sharmistha Dey
A novel antimicrobial peptide derived from modified N-terminal domain of bovine lactoferrin: design, synthesis, activity against multidrug-resistant bacteria and Candida.
Biochimica et biophysica acta 2013;1828(2):677-86.
2013: Rahul Kumar; Prakash K Sharma; Abhay K Singh; Manjari Tripathi; Prasun Chaterjee; Aparajit B Dey; Kamaldeep Gill; Abhishek Gupta; Sharmistha Dey
Sirtuin1: a promising serum protein marker for early detection of Alzheimer's disease.
PloS one 2013;8(4):e61560.
2013: Pradeep Sharma; Sujata Sharma; Amar Singh; Abhay Kumar Singh; Sharmistha Dey; Divya Dube; Punit Kaur; Gorakh Mal; Dipendra K Mitra; Nisha Pandey; Mau Sinha; Shavait Yamini; Tej P Singh
Structural basis of the binding of fatty acids to peptidoglycan recognition protein, PGRP-S through second binding site.
Archives of biochemistry and biophysics 2013;529(1):1-10.
2012: Vijay Kumar; Abhay Kumar Singh; Sarman Singh; Tej P Singh; Vikash Kumar Yadav; Md Imtaiyaz Hassan; Sharmistha Dey; Savita Yadav
Kinetic and structural studies on the interactions of heparin and proteins of human seminal plasma using surface plasmon resonance.
Protein and peptide letters 2012;19(8):795-803.
2012: Abhay Kumar Singh; Nidhi Singh; Ratnakar Singh; Savita Yadav; Kamaldeep Gill; Sujoy Pal; Roshan Pandey; Anoop Saraya; Shyam S Chauhan; Sharmistha Dey
p38β MAP kinase as a therapeutic target for pancreatic cancer.
Chemical biology & drug design 2012;80(2):266-73.
2012: Kamaldeep Gill; Bidhu Kalyan Mohanti; Abhay Kumar Singh; Md Saquib Ashraf; Sharmistha Dey
Quantification of p38αMAP kinase: a prognostic marker in HNSCC with respect to radiation therapy.
Clinica chimica acta; international journal of clinical chemistry 2012;413(1-2):219-25.
2012: Nirmal Chhikara; Sharmistha Dey; Mayank Saraswat; Sarman Singh; Anil Kumar Tomar; Savita Yadav
Human epididymis protein-4 (HE-4): a novel cross-class protease inhibitor.
PloS one 2012;7(11):e47672.
2012: Pradeep Sharma; Sujata Sharma; Sharmistha Dey; Divya Dube; Punit Kaur; Mau Sinha; Tej P Singh
Structural basis of heparin binding to camel peptidoglycan recognition protein-S.
International journal of biochemistry and molecular biology 2012;3(1):86-94.
2012: Abhay Kumar Singh; Ratnakar Singh; Shyam S Chauhan; Amit Dinda; Kamaldeep Gill; Vaishali Kapoor; Farhat Naz; Abhay Anand Shukla; Sharmistha Dey
Structure based design and synthesis of peptide inhibitor of human LOX-12: in vitro and in vivo analysis of a novel therapeutic agent for breast cancer.
PloS one 2012;7(2):e32521.
2011: Abhay Kumar Singh; Nirupama Banerjee; Sashi Kant; Rajinder Parshad; Sharmistha Dey
Evaluation of human LOX-12 as a serum marker for breast cancer.
Biochemical and biophysical research communications 2011;414(2):304-8.
2011: Abhay Kumar Singh; Krishna Dalal; Satya N Das; Kamaldeep Gill; Thirumurthy Madhavan; Biswajit Mishra; Rajinder Parshad; Shweta Pasi; Sharmistha Dey
Prognostic significance of cyclooxygenase-2 and response to chemotherapy in invasive ductal breast carcinoma patients by real time surface plasmon resonance analysis.
DNA and cell biology 2011;30(10):801-7.
2011: Pradeep Sharma; Sujata Sharma; Mau Sinha; Sharmistha Dey; Divya Dube; Punit Kaur; Gorakh Mal; Biswajit Mishra; Krishan M L Pathak; Tej P Singh
Multiligand specificity of pathogen-associated molecular pattern-binding site in peptidoglycan recognition protein.
The Journal of biological chemistry 2011;286(36):31723-30.
2011: Kamaldeep Gill; Biswajit Mishra; Bidhu Kalyan Mohanti; Abhay Kumar Singh; Sharmistha Dey
The over expression of cathelicidin peptide LL37 in head and neck squamous cell carcinoma: the peptide marker for the prognosis of cancer.
Cancer biomarkers : section A of Disease markers 2011;10(3-4):125-34.
2011: Swagata Das; Biswajit Mishra; Kamaldeep Gill; Md Saquib Ashraf; Abhay Kumar Singh; Mou Sinha; Sujata Sharma; Immaculata Xess; Krishna Dalal; Tej Pal Singh; Sharmistha Dey
Isolation and characterization of novel protein with anti-fungal and anti-inflammatory properties from Aloe vera leaf gel.
International journal of biological macromolecules 2011;48(1):38-43.
2010: Vaishali Kapoor; Abhay K Singh; Sharmistha Dey; Suresh C Sharma; Sambhu N Das
Circulating cycloxygenase-2 in patients with tobacco-related intraoral squamous cell carcinoma and evaluation of its peptide inhibitors as potential antitumor agent.
Journal of cancer research and clinical oncology 2010;136(12):1795-804.
2010: Biswajit Mishra; Vipul Kumar Srivastava; Rama Chaudhry; rishi somvanshi; Abhay Kumar Singh; Kamaldeep Gill; Ramesh Somvanshi; Ishan Kumar Patro; Sharmistha Dey
SD-8, a novel therapeutic agent active against multidrug-resistant Gram positive cocci.
Amino acids 2010;39(5):1493-505.
2010: Sanjit Kumar; Nagendra Singh; Biswajit Mishra; Divya Dube; Mau Sinha; S Baskar Singh; Sharmistha Dey; Punit Kaur; Sujata Sharma; Tej P Singh
Modulation of inhibitory activity of xylanase-α-amylase inhibitor protein (XAIP): binding studies and crystal structure determination of XAIP-II from Scadoxus multiflorus at 1.2 Å resolution.
BMC structural biology 2010;10():41.
2009: Vijay Kumar; Md Imtaiyaz Hassan; Abhay Kumar Singh; Sharmistha Dey; Tej P Singh; Savita Yadav
Strategy for sensitive and specific detection of molecular forms of PSA based on 2DE and kinetic analysis: a step towards diagnosis of prostate cancer.
Clinica chimica acta; international journal of clinical chemistry 2009;403(1-2):17-22.
2008: rishi somvanshi; Abhay Kumar Singh; Meera Saxena; Biswajit Mishra; Sharmistha Dey
Development of novel peptide inhibitor of Lipoxygenase based on biochemical and BIAcore evidences.
Biochimica et biophysica acta 2008;1784(11):1812-7.
2007: Md Imtaiyaz Hassan; Vijay Kumar; rishi somvanshi; Sharmistha Dey; Tej P Singh; savita yadav
Structure-guided design of peptidic ligand for human prostate specific antigen.
Journal of peptide science : an official publication of the European Peptide Society 2007;13(12):849-55.
2007: rishi somvanshi; Ashwini Kumar; Shashi Kant; Deepti Gupta; S Bhaskar Singh; Utpal Das; Alagiri Srinivasan; Tej P Singh; Sharmistha Dey
Surface plasmon resonance studies and biochemical evaluation of a potent peptide inhibitor against cyclooxygenase-2 as an anti-inflammatory agent.
Biochemical and biophysical research communications 2007;361(1):37-42.
2007: Devendra B Srivastava; Abdul S Ethayathulla; Janesh Kumar; rishi somvanshi; Sujata Sharma; Sharmistha Dey; Tej P Singh
Carbohydrate binding properties and carbohydrate induced conformational switch in sheep secretory glycoprotein (SPS-40): crystal structures of four complexes of SPS-40 with chitin-like oligosaccharides.
Journal of structural biology 2007;158(3):255-66.
2007: Kolandaivelu Saravanan; Gururao Hariprasad; O Jitesh; Utpal Das; Sharmistha Dey; Sujata Sharma; Punit Kaur; Tej P Singh; Alagiri Srinivasan
Endothelin and its receptor interactions: role of extracellular receptor domain and length of peptide ligands.
Protein and peptide letters 2007;14(8):779-83.
2007: Nagendra Singh; rishi somvanshi; Sujata Sharma; Sharmistha Dey; Punit Kaur; Tej P Singh
Structural elements of ligand recognition site in secretory phospho-lipase A2 and structure-based design of specific inhibitors.
Current topics in medicinal chemistry 2007;7(8):757-64.
2006: Nagendra Singh; Talat Jabeen; Sujata Sharma; rishi somvanshi; Sharmistha Dey; Alagiri Srinivasan; Tej P Singh
Specific binding of non-steroidal anti-inflammatory drugs (NSAIDs) to phospholipase A2: structure of the complex formed between phospholipase A2 and diclofenac at 2.7 A resolution.
Acta crystallographica. Section D, Biological crystallography 2006;62(Pt 4):410-6.
2005: Talat Jabeen; Nagendra Singh; Rajendra Kumar Singh; Sujata Sharma; rishi somvanshi; Sharmistha Dey; Tej P Singh
Non-steroidal anti-inflammatory drugs as potent inhibitors of phospholipase A2: structure of the complex of phospholipase A2 with niflumic acid at 2.5 Angstroms resolution.
Acta crystallographica. Section D, Biological crystallography 2005;61(Pt 12):1579-86.
2005: V K Goel; rishi somvanshi; Sharmistha Dey; Tej P Singh
Effects of branched beta-carbon dehydro-residues on peptide conformations: syntheses, crystal structures and molecular conformations of two tetrapeptides: (a) N-(benzyloxycarbonyl)-DeltaVal-Leu-DeltaPhe-Leu-OCH3 and (b) N-(benzyloxycarbonyl)-DeltaIle-Ala-DeltaPhe-Ala-OCH3.
The journal of peptide research : official journal of the American Peptide Society 2005;66(2):68-74.
2005: Rajendra Kumar Singh; Nagendra Singh; Talat Jabeen; Sujata Sharma; Sharmistha Dey; Tej P Singh
Crystal structure of the complex of group I PLA2 with a group II-specific peptide Leu-Ala-Ile-Tyr-Ser (LAIYS) at 2.6 A resolution.
Journal of drug targeting 2005;13(6):367-74.
2005: Nagendra Singh; Talat Jabeen; Sujata Sharma; Ipsita Roy; Munishwar N Gupta; Sameeta Bilgrami; rishi somvanshi; Sharmistha Dey; Markus Perbandt; Christian Betzel; Alagiri Srinivasan; Tej P Singh
Detection of native peptides as potent inhibitors of enzymes. Crystal structure of the complex formed between treated bovine alpha-chymotrypsin and an autocatalytically produced fragment, IIe-Val-Asn-Gly-Glu-Glu-Ala-Val-Pro-Gly-Ser-Trp-Pro-Trp, at 2.2 angstroms resolution.
The FEBS journal 2005;272(2):562-72.
2004: Nagendra Singh; Talat Jabeen; rishi somvanshi; Sujata Sharma; Sharmistha Dey; Tej P Singh
Phospholipase A2 as a target protein for nonsteroidal anti-inflammatory drugs (NSAIDS): crystal structure of the complex formed between phospholipase A2 and oxyphenbutazone at 1.6 A resolution.
Biochemistry 2004;43(46):14577-83.
2004: Kolandaivelu Saravanan; Murugan Paramasivam; Sharmistha Dey; Tej P Singh; Alagiri Srinivasan
Biotinyl endothelin-1 binding to endothelin receptor and its applications.
Journal of cardiovascular pharmacology 2004;44(3):287-93.
2003: Rajendra Kumar Singh; P Vikram; Jyoti Makker; Talat Jabeen; Sujata Sharma; Sharmistha Dey; Punit Kaur; Alagiri Srinivasan; Tej P Singh
Design of specific peptide inhibitors for group I phospholipase A2: structure of a complex formed between phospholipase A2 from Naja naja sagittifera (group I) and a designed peptide inhibitor Val-Ala-Phe-Arg-Ser (VAFRS) at 1.9 A resolution reveals unique features.
Biochemistry 2003;42(40):11701-6.
2003: R Vijayaraghavan; Pravindra Kumar; Sharmistha Dey; Tej P Singh
Design of peptides with branched beta-carbon dehydro-residues: syntheses, crystal structures and molecular conformations of two peptides, (I) N-Carbobenzoxy-DeltaVal-Ala-Leu-OCH3 and (II) N-Carbobenzoxy-DeltaIle-Ala-Leu-OCH3.
The journal of peptide research : official journal of the American Peptide Society 2003;62(2):63-9.
2002: Vikas Chandra; Jayasankar Jasti; Punit Kaur; Sharmistha Dey; Markus Perbandt; Alagiri Srinivasan; Christian Betzel; Tej P Singh
Crystal structure of a complex formed between a snake venom phospholipase A(2) and a potent peptide inhibitor Phe-Leu-Ser-Tyr-Lys at 1.8 A resolution.
The Journal of biological chemistry 2002;277(43):41079-85.
2002: Vikas Chandra; Jayasankar Jasti; Punit Kaur; Sharmistha Dey; Alagiri Srinivasan; Christian Betzel; Tej P Singh
Design of specific peptide inhibitors of phospholipase A2: structure of a complex formed between Russell's viper phospholipase A2 and a designed peptide Leu-Ala-Ile-Tyr-Ser (LAIYS).
Acta crystallographica. Section D, Biological crystallography 2002;58(Pt 10 Pt 2):1813-9.
2002: Jyoti Makker; Sharmistha Dey; Pravindra Kumar; Tej P Singh
Design of peptides with alpha,beta-dehydro residues: pseudo-tripeptide N-benzyloxycarbonyl-DeltaLeu-L-Ala-L-Leu-OCH3.
Acta crystallographica. Section C, Crystal structure communications 2002;58(Pt 4):O212-4.
2001: R Vijayaraghavan; Pravindra Kumar; Sharmistha Dey; Tej P Singh
Design of peptides with alpha,beta-dehydro residues: a dipeptide with a branched beta-carbon dehydro residue at the (i+1) position, methyl N-(benzyloxycarbonyl)-alpha,beta-didehydrovalyl-L-tryptophanate.
Acta crystallographica. Section C, Crystal structure communications 2001;57(Pt 10):1220-1.
2001: Neelima Alam; Samudrala Gourinath; Sharmistha Dey; Alagiri Srinivasan; Tej P Singh
Substrate-inhibitor interactions in the kinetics of alpha-amylase inhibition by ragi alpha-amylase/trypsin inhibitor (RATI) and its various N-terminal fragments.
Biochemistry 2001;40(14):4229-33.
1998: R Vijayaraghavan; Pravindra Kumar; Sharmistha Dey; Tej P Singh
Design of peptides with alpha,beta-dehydro residues: synthesis, crystal structure and molecular conformation of N-Boc-L-Ile-deltaPhe-L-Trp-OCH3.
The journal of peptide research : official journal of the American Peptide Society 1998;52(2):89-94.