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Jean-François Dhainaut

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V Marco Ranieri; Andrew Rhodes; Jyrki Tenhunen; B Taylor Thompson; Vivian Thompson; Burkhard Vangerow; Mark D Williams; Hussein R Al-Khalidi; Antonio Artigas; Philip S Barie; Jean-François Dhainaut; Ivor S Douglas; Simon Finfer; Bengt Gårdlund; Jonathan Janes; William L Macias; John C Marshall; Didier Payen
Drotrecogin alfa (activated) in adults with septic shock.
V Marco Ranieri; Andrew Rhodes; B Taylor Thompson; Philip S Barie; Jean-François Dhainaut; Ivor S Douglas; Simon Finfer; Bengt Gårdlund; John C Marshall
Unblinding plan of PROWESS-SHOCK trial.
Richard G Wunderink; Christian Zwingelstein; Antonio Artigas; Jean-François Dhainaut; Christopher Doig; Thierry Dugernier; Bruno Francois; Sung Chul Hwang; Jorge San Juan; Steven LaRosa; Pierre-François Laterre; Suzana M Lobo; Meryl H Mendelson; Steven Opal; Dominique Perrotin; Guoqin Su; Luis Otero Vidal; Xavier Wittebole
Recombinant tissue factor pathway inhibitor in severe community-acquired pneumonia: a randomized trial.

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2012: V Marco Ranieri; Andrew Rhodes; Jyrki Tenhunen; B Taylor Thompson; Vivian Thompson; Burkhard Vangerow; Mark D Williams; Hussein R Al-Khalidi; Antonio Artigas; Philip S Barie; Jean-François Dhainaut; Ivor S Douglas; Simon Finfer; Bengt Gårdlund; Jonathan Janes; William L Macias; John C Marshall; Didier Payen
Drotrecogin alfa (activated) in adults with septic shock.
The New England journal of medicine 2012;366(22):2055-64.
2011: V Marco Ranieri; Andrew Rhodes; B Taylor Thompson; Philip S Barie; Jean-François Dhainaut; Ivor S Douglas; Simon Finfer; Bengt Gårdlund; John C Marshall
Unblinding plan of PROWESS-SHOCK trial.
Intensive care medicine 2011;37(8):1384-5.
2011: Richard G Wunderink; Christian Zwingelstein; Antonio Artigas; Jean-François Dhainaut; Christopher Doig; Thierry Dugernier; Bruno Francois; Sung Chul Hwang; Jorge San Juan; Steven LaRosa; Pierre-François Laterre; Suzana M Lobo; Meryl H Mendelson; Steven Opal; Dominique Perrotin; Guoqin Su; Luis Otero Vidal; Xavier Wittebole
Recombinant tissue factor pathway inhibitor in severe community-acquired pneumonia: a randomized trial.
American journal of respiratory and critical care medicine 2011;183(11):1561-8.
2009: Jean-François Dhainaut; Massimo Antonelli; Patrick Wright; Arnaud Desachy; Jean Reignier; Sylvain Lavoue; Julien Charpentier; Mark Belger; Michael Cobas-Meyer; Cornelia Maier; Mariano A Mignini; Jonathan Janes
Extended drotrecogin alfa (activated) treatment in patients with prolonged septic shock.
Intensive care medicine 2009;35(7):1187-95.
2009: Jean-Christophe Allo; Jean-Francois Vigneau; Jie Jiang; Roger Ranerison; Elie Caroline; Aurélie Dabreteau; Guillaume Der Sahakian; Franck Perruche; Jean-François Dhainaut; Fabrice Brunet; Yann-Erick Claessens
Appropriateness of diagnosis and orientation of 996 consecutive patients admitted in an emergency department with flow-based organization.
European journal of emergency medicine : official journal of the European Society for Emergency Medicine 2009;16(1):23-8.
2009: Jean-François Dhainaut
Role of clinical evaluation committees in sepsis trials: from 'valid cohort' assessment to subgroup analysis.
Critical care (London, England) 2009;13(2):124.
2008: Simon Finfer; V Marco Ranieri; B Taylor Thompson; Philip Barie; Jean-François Dhainaut; Ivor S Douglas; Bengt Gårdlund; John C Marshall; Andrew Rhodes
Design, conduct, analysis and reporting of a multi-national placebo-controlled trial of activated protein C for persistent septic shock.
Intensive care medicine 2008;34(11):1935-47.
2008: Alain Cariou; Michael R Pinsky; Mehran Monchi; Ivan Laurent; Christophe Vinsonneau; Jean-Daniel Chiche; Julien Charpentier; Jean-François Dhainaut
Is myocardial adrenergic responsiveness depressed in human septic shock?
Intensive care medicine 2008;34(5):917-22.
2008: Jean-François Dhainaut
International integrated database for the evaluation of severe sepsis (INDEPTH): clinical evaluation committee report on the safety of drotrecogin alfa (activated) therapy.
Current medical research and opinion 2008;24(4):1187-97.
2008: Pierre-François Laterre; William L Macias; Jonathan Janes; Mark D Williams; David Nelson; Amand R J Girbes; Jean-François Dhainaut; Edward Abraham
Influence of enrollment sequence effect on observed outcomes in the ADDRESS and PROWESS studies of drotrecogin alfa (activated) in patients with severe sepsis.
Critical care (London, England) 2008;12(5):R117.
2007: Guillaume Der Sahakian; Franck Perruche; Aurélie Dabreteau; Jean-François Dhainaut; Yann-Erick Claessens; Jean-Christophe Allo
Aspiration pneumonitis and Newton's law of gravitation.
The American journal of emergency medicine 2007;25(8):987.e1-2.
2007: Yann-Erick Claessens; Jean-François Dhainaut
Diagnosis and treatment of severe sepsis.
Critical care (London, England) 2007;11 Suppl 5():S2.
2007: Jean-François Dhainaut; Stéphanie Payet; Benoit Vallet; Lionel Riou França; Djillali Annane; Pierre-Edouard Bollaert; Yves Le Tulzo; Isabelle Runge; Yannick Malledant; Bertrand Guidet; Katell Le Lay; Robert Launois
Cost-effectiveness of activated protein C in real-life clinical practice.
Critical care (London, England) 2007;11(5):R99.
2006: Khalil Takun; Guillaume Der Sahakian; Frederic Bloch; Jamal Kansao; Jean-François Dhainaut
Health network to improve elderly patients' flow in emergency department.
European journal of emergency medicine : official journal of the European Society for Emergency Medicine 2006;13(5):260-3.
2006: T Cartier; P Sogni; F Perruche; O Meyniard; Yann-Erick Claessens; Jean-François Dhainaut; Guillaume Der Sahakian
Normal lipase serum level in acute pancreatitis: a case report.
Emergency medicine journal : EMJ 2006;23(9):701-2.
2006: Christophe Vinsonneau; Christophe Camus; Alain Combes; Marie-Alyette Costa De Beauregard; Kada Klouche; thierry boulain; Jean-Louis Pallot; Jean-Daniel Chiche; Pierre Taupin; Paul Landais; Jean-François Dhainaut
Continuous venovenous haemodiafiltration versus intermittent haemodialysis for acute renal failure in patients with multiple-organ dysfunction syndrome: a multicentre randomised trial.
Lancet 2006;368(9533):379-85.
2006: Yann-Erick Claessens; Michaëla Fontenay; Frédéric Pene; Jean-Daniel Chiche; Martine Guesnu; Cyrla Hababou; Nicole Casadevall; Jean-François Dhainaut; Jean-Paul Mira; Alain Cariou
Erythropoiesis abnormalities contribute to early-onset anemia in patients with septic shock.
American journal of respiratory and critical care medicine 2006;174(1):51-7.
2006: Yann-Erick Claessens; Pierre Taupin; Gérald Kierzek; Jean-Louis Pourriat; Michel Baud; Christine Ginsburg; Jean-Philippe jais; Eric Jougla; Bruno Riou; Jean-François Dhainaut; Paul Landais
How emergency departments might alert for prehospital heat-related excess mortality?
Critical care (London, England) 2006;10(6):R156.
2006: Sophie Marque; Alain Cariou; Jean-Daniel Chiche; Vincent O Mallet; Frédéric Pene; Jean-Paul Mira; Jean-François Dhainaut; Yann-Erick Claessens
Risk factors for post-ICU red blood cell transfusion: a prospective study.
Critical care (London, England) 2006;10(5):R129.
2006: Andrew F Shorr; gordon bernard; Jean-François Dhainaut; James R Russell; William L Macias; David Nelson; David P Sundin
Protein C concentrations in severe sepsis: an early directional change in plasma levels predicts outcome.
Critical care (London, England) 2006;10(3):R92.
2005: Jean-François Dhainaut; Yann-Erick Claessens; Jonathan Janes; David Nelson
Underlying disorders and their impact on the host response to infection.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2005;41 Suppl 7():S481-9.
2005: Jean-Louis Vincent; gordon bernard; Richard Beale; Christopher Doig; Christian Putensen; Jean-François Dhainaut; Antonio Artigas; Roberto Fumagalli; William L Macias; Theressa Wright; Kar Wong; David P Sundin; Mary Ann Turlo; Jonathan Janes
Drotrecogin alfa (activated) treatment in severe sepsis from the global open-label trial ENHANCE: further evidence for survival and safety and implications for early treatment.
Critical care medicine 2005;33(10):2266-77.
2005: Ivan Laurent; Christophe Adrie; Christophe Vinsonneau; Alain Cariou; Jean-Daniel Chiche; Alice Ohanessian; Christian Spaulding; Pierre Carli; Jean-François Dhainaut; Mehran Monchi
High-volume hemofiltration after out-of-hospital cardiac arrest: a randomized study.
Journal of the American College of Cardiology 2005;46(3):432-7.
2005: Christophe Adrie; Mehran Monchi; Ivan Laurent; Suzan Um; S Betty Yan; Marie Thuong; Alain Cariou; Julien Charpentier; Jean-François Dhainaut
Coagulopathy after successful cardiopulmonary resuscitation following cardiac arrest: implication of the protein C anticoagulant pathway.
Journal of the American College of Cardiology 2005;46(1):21-8.
2005: Pierre-François Laterre; Gary E Garber; Howard Levy; Richard G Wunderink; Gary T Kinasewitz; Jean-Pierre Sollet; Dennis G Maki; Becky M Bates; Sau Chi Betty Yan; Jean-François Dhainaut
Severe community-acquired pneumonia as a cause of severe sepsis: data from the PROWESS study.
Critical care medicine 2005;33(5):952-61.
2005: Sébastien Lacroix-Desmazes; Jagadeesh Bayry; Srini V Kaveri; David Hayon-Sonsino; Nithyananda Thorenoor; Julien Charpentier; Charles-Edouard Luyt; Jean-Paul Mira; Valakunja Nagaraja; Michel D Kazatchkine; Jean-François Dhainaut; Vincent O Mallet
High levels of catalytic antibodies correlate with favorable outcome in sepsis.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(11):4109-13.
2005: Jean-François Dhainaut; Andrew F Shorr; William L Macias; Marin J Kollef; Marcel Levi; Konrad Reinhart; David Nelson
Dynamic evolution of coagulopathy in the first day of severe sepsis: relationship with mortality and organ failure.
Critical care medicine 2005;33(2):341-8.
2005: Madiha Ellaffi; Christophe Vinsonneau; Joel Coste; Dominique Hubert; Pierre-Régis Burgel; Jean-François Dhainaut; Daniel Dusser
One-year outcome after severe pulmonary exacerbation in adults with cystic fibrosis.
American journal of respiratory and critical care medicine 2005;171(2):158-64.
2004: William L Macias; Benoit Vallet; gordon bernard; Jean-Louis Vincent; Pierre-François Laterre; David Nelson; P Alexander Derchak; Jean-François Dhainaut
Sources of variability on the estimate of treatment effect in the PROWESS trial: implications for the design and conduct of future studies in severe sepsis.
Critical care medicine 2004;32(12):2385-91.
2004: Pierre-François Laterre; Howard Levy; Gilles Clermont; Daniel E Ball; Rekha Garg; David Nelson; Jean-François Dhainaut; Derek C Angus
Hospital mortality and resource use in subgroups of the Recombinant Human Activated Protein C Worldwide Evaluation in Severe Sepsis (PROWESS) trial.
Critical care medicine 2004;32(11):2207-18.
2004: Jean-François Dhainaut; S Betty Yan; D E Joyce; V Pettilä; Bruce R Basson; J T Brandt; David P Sundin; Marcel Levi
Treatment effects of drotrecogin alfa (activated) in patients with severe sepsis with or without overt disseminated intravascular coagulation.
Journal of thrombosis and haemostasis : JTH 2004;2(11):1924-33.
2004: Alain Cariou; Christophe Vinsonneau; Jean-François Dhainaut
Adjunctive therapies in sepsis: an evidence-based review.
Critical care medicine 2004;32(11 Suppl):S562-70.
2004: Jean-François Dhainaut; S Betty Yan; Yann-Erick Claessens
Protein C/activated protein C pathway: overview of clinical trial results in severe sepsis.
Critical care medicine 2004;32(5 Suppl):S194-201.
2004: Cyril Goulenok; Mehran Monchi; Jean-Daniel Chiche; Jean-Paul Mira; Jean-François Dhainaut; Alain Cariou
Influence of overweight on ICU mortality: a prospective study.
Chest 2004;125(4):1441-5.
2004: Gary T Kinasewitz; S Betty Yan; Bruce R Basson; Philip C Comp; James A Russell; Alain Cariou; Suzane L Um; Barbara G Utterback; Pierre-François Laterre; Jean-François Dhainaut
Universal changes in biomarkers of coagulation and inflammation occur in patients with severe sepsis, regardless of causative micro-organism [ISRCTN74215569].
Critical care (London, England) 2004;8(2):R82-90.
2004: Julien Charpentier; Charles-Edouard Luyt; Yvonne Fulla; Christophe Vinsonneau; Alain Cariou; Sophie Grabar; Jean-François Dhainaut; Jean-Paul Mira; Jean-Daniel Chiche
Brain natriuretic peptide: A marker of myocardial dysfunction and prognosis during severe sepsis.
Critical care medicine 2004;32(3):660-5.
2004: Jean-François Dhainaut; Yann-Erick Claessens; Christine Ginsburg; Bruno Riou
Unprecedented heat-related deaths during the 2003 heat wave in Paris: consequences on emergency departments.
Critical care (London, England) 2004;8(1):1-2.
2004: S Betty Yan; Jean-François Dhainaut; Hans Peter Schwarz; Hartmut J Ehrlich
Only activated protein C treatment and not protein C has demonstrated an improvement in survival in severe sepsis.
Critical care medicine 2004;32(2):618; author reply 618-9.
2004: Steven M Opal; Pierre-François Laterre; Edward Abraham; Bruno Francois; Xavier Wittebole; Stephen Lowry; Jean-François Dhainaut; Brian Warren; Thierry Dugernier; Angel Lopez; Miguel Sanchez; Ignace Demeyer; Luis Jauregui; Jose Angel Lorente; William McGee; Konrad Reinhart; Sascha Kljucar; Sonia Souza; John P Pribble
Recombinant human platelet-activating factor acetylhydrolase for treatment of severe sepsis: results of a phase III, multicenter, randomized, double-blind, placebo-controlled, clinical trial.
Critical care medicine 2004;32(2):332-41.
2003: Jean-François Dhainaut; C Gaillez; Alain Cariou
[Mechanisms involved in the activation of the protein C pathway in sepsis].
Annales françaises d'anesthèsie et de rèanimation 2003;22 Spec No 1():3-11.
2003: Bryce A Kerlin; S Betty Yan; Berend Isermann; John T Brandt; Rashmi Sood; Bruce R Basson; David E Joyce; Hartmut Weiler; Jean-François Dhainaut
Survival advantage associated with heterozygous factor V Leiden mutation in patients with severe sepsis and in mouse endotoxemia.
Blood 2003;102(9):3085-92.
2003: Jean-François Dhainaut; S Betty Yan; Benjamin D Margolis; José A Lorente; James A Russell; Ross Freebairn; Herbert Spapen; Hanno Riess; Bruce R Basson; Gerald Johnson; Gary T Kinasewitz
Drotrecogin alfa (activated) (recombinant human activated protein C) reduces host coagulopathy response in patients with severe sepsis.
Thrombosis and haemostasis 2003;90(4):642-53.
2003: Jean-François Dhainaut; Pierre-François Laterre; Steven P LaRosa; Howard Levy; Gary E Garber; Darell E Heiselman; Gary T Kinasewitz; R Bruce Light; Peter Morris; Roland M H Schein; Jean-Pierre Sollet; Becky M Bates; Barbara G Utterback; Dennis G Maki
The clinical evaluation committee in a large multicenter phase 3 trial of drotrecogin alfa (activated) in patients with severe sepsis (PROWESS): role, methodology, and results.
Critical care medicine 2003;31(9):2291-301.
2003: Steven M Opal; Gary E Garber; Steven P LaRosa; Dennis G Maki; Ross Freebairn; Gary T Kinasewitz; Jean-François Dhainaut; S Betty Yan; Mark D Williams; Delores E Graham; David Nelson; Howard Levy; gordon bernard
Systemic host responses in severe sepsis analyzed by causative microorganism and treatment effects of drotrecogin alfa (activated).
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2003;37(1):50-8.
2003: Herwig Gerlach; Jean-François Dhainaut; Stephan Harbarth; Konrad Reinhart; John C Marshall; Mitchell Levy
The PIRO concept: R is for response.
Critical care (London, England) 2003;7(3):256-9.
2003: Jean-François Dhainaut; Pierre-François Laterre; Jonathan Janes; gordon bernard; Antonio Artigas; Jan Bakker; Hanno Riess; Bruce R Basson; Julien Charpentier; Barbara G Utterback; Jean-Louis Vincent
Drotrecogin alfa (activated) in the treatment of severe sepsis patients with multiple-organ dysfunction: data from the PROWESS trial.
Intensive care medicine 2003;29(6):894-903.
2003: Yann-Erick Claessens; Alain Cariou; Mehran Monchi; Lilia Soufir; Elie Azoulay; Philippe Rouges; Dany Goldgran-Toledano; Fabienne Branche; Jean-François Dhainaut
Detecting life-threatening lactic acidosis related to nucleoside-analog treatment of human immunodeficiency virus-infected patients, and treatment with L-carnitine.
Critical care medicine 2003;31(4):1042-7.
2003: Pierre-François Laterre; Xavier Wittebole; Jean-François Dhainaut
Anticoagulant therapy in acute lung injury.
Critical care medicine 2003;31(4 Suppl):S329-36.
2003: Jean-François Dhainaut; Julien Charpentier; Jean-Daniel Chiche
Transforming growth factor-beta: a mediator of cell regulation in acute respiratory distress syndrome.
Critical care medicine 2003;31(4 Suppl):S258-64.
2003: Jean-François Dhainaut; Nathalie Marin; Julien Charpentier
[Activated protein C and septic shock].
La Revue du praticien 2003;53(1):5-6.
2003: E Wesley Ely; Pierre-François Laterre; Derek C Angus; Jeffrey D Helterbrand; Howard Levy; Jean-François Dhainaut; Jean-Louis Vincent; William L Macias; gordon bernard
Drotrecogin alfa (activated) administration across clinically important subgroups of patients with severe sepsis.
Critical care medicine 2003;31(1):12-9.
2002: Ivan Laurent; Mehran Monchi; Jean-Daniel Chiche; Luc-Marie Joly; Christian Spaulding; Bénédicte Bourgeois; Alain Cariou; Alain Rozenberg; Pierre Carli; Simon Weber; Jean-François Dhainaut
Reversible myocardial dysfunction in survivors of out-of-hospital cardiac arrest.
Journal of the American College of Cardiology 2002;40(12):2110-6.
2002: Jean-François Dhainaut
Introduction: rationale for using drotrecogin alfa (activated) in patients with severe sepsis.
American journal of surgery 2002;184(6A Suppl):S5-10.
2002: William L Macias; Jean-François Dhainaut; Sau Chi Betty Yan; Jeffrey D Helterbrand; Mary Seger; Gerald Johnson; David S Small
Pharmacokinetic-pharmacodynamic analysis of drotrecogin alfa (activated) in patients with severe sepsis.
Clinical pharmacology and therapeutics 2002;72(4):391-402.
2002: Christophe Adrie; Minou Adib-Conquy; Ivan Laurent; Mehran Monchi; Christophe Vinsonneau; Catherine Fitting; François Fraisse; Anh Tuan Dinh-Xuan; Pierre Carli; Christian Spaulding; Jean-François Dhainaut; Jean-Marc Cavaillon
Successful cardiopulmonary resuscitation after cardiac arrest as a "sepsis-like" syndrome.
Circulation 2002;106(5):562-8.
2002: Alain Cariou; Jean-Daniel Chiche; Julien Charpentier; Jean-François Dhainaut; Jean-Paul Mira
The era of genomics: impact on sepsis clinical trial design.
Critical care medicine 2002;30(5 Suppl):S341-8.
2002: Jean-François Dhainaut; S Betty Yan; Alain Cariou; Jean-Paul Mira
Soluble thrombomodulin, plasma-derived unactivated protein C, and recombinant human activated protein C in sepsis.
Critical care medicine 2002;30(5 Suppl):S318-24.
2001: Elie Azoulay; Frédéric Pochard; Sylvie Chevret; Christophe Vinsonneau; M Garrouste; Yves Cohen; Marie Thuong; C Paugam; C Apperre; B De Cagny; Frédéric Brun; Caroline Bornstain; Antoine Parrot; F Thamion; J C Lacherade; Y Bouffard; Jean-Roger Le Gall; C Herve; Marc Grassin; R Zittoun; Benoît Schlemmer; Jean-François Dhainaut
Compliance with triage to intensive care recommendations.
Critical care medicine 2001;29(11):2132-6.
2001: Jean-Louis Vincent; R Brase; F Santman; Peter Suter; A McLuckie; Jean-François Dhainaut; Y Park; J Karmel
A multi-centre, double-blind, placebo-controlled study of liposomal prostaglandin E1 (TLC C-53) in patients with acute respiratory distress syndrome.
Intensive care medicine 2001;27(10):1578-83.
2001: Frédéric Pochard; Elie Azoulay; Sylvie Chevret; F Lemaire; P Hubert; P Canoui; Marc Grassin; R Zittoun; Jean-Roger Le Gall; Jean-François Dhainaut; Benoît Schlemmer
Symptoms of anxiety and depression in family members of intensive care unit patients: ethical hypothesis regarding decision-making capacity.
Critical care medicine 2001;29(10):1893-7.
2001: Frédéric Pochard; Elie Azoulay; Sylvie Chevret; Christophe Vinsonneau; Marc Grassin; F Lemaire; C Hervé; Benoît Schlemmer; R Zittoun; Jean-François Dhainaut
French intensivists do not apply American recommendations regarding decisions to forgo life-sustaining therapy.
Critical care medicine 2001;29(10):1887-92.
2001: Christophe Adrie; Maria Bachelet; Muriel Vayssier-Taussat; F Russo-Marie; I Bouchaert; Minou Adib-Conquy; Jean-Marc Cavaillon; M R Pinsky; Jean-François Dhainaut; Barbara S Polla
Mitochondrial membrane potential and apoptosis peripheral blood monocytes in severe human sepsis.
American journal of respiratory and critical care medicine 2001;164(3):389-95.
2001: S Betty Yan; Jean-François Dhainaut
Activated protein C versus protein C in severe sepsis.
Critical care medicine 2001;29(7 Suppl):S69-74.
2001: Jean-François Dhainaut; Nathalie Marin; A Mignon; Christophe Vinsonneau
Hepatic response to sepsis: interaction between coagulation and inflammatory processes.
Critical care medicine 2001;29(7 Suppl):S42-7.
2001: Christophe Adrie; Mehran Monchi; Anh Tuan Dinh-Xuan; Josette Dall'Ava-Santucci; Jean-François Dhainaut; M R Pinsky
Exhaled and nasal nitric oxide as a marker of pneumonia in ventilated patients.
American journal of respiratory and critical care medicine 2001;163(5):1143-9.
2001: gordon bernard; Jean-Louis Vincent; Pierre-François Laterre; Steven P LaRosa; Jean-François Dhainaut; A Lopez-Rodriguez; Jay S Steingrub; Gary E Garber; Jeffrey D Helterbrand; E Wesley Ely; Charles J Fisher
Efficacy and safety of recombinant human activated protein C for severe sepsis.
The New England journal of medicine 2001;344(10):699-709.
2001: E Azoulay; Frédéric Pochard; S Chevret; F Lemaire; M Mokhtari; J R Le Gall; Jean-François Dhainaut; B Schlemmer
Meeting the needs of intensive care unit patient families: a multicenter study.
American journal of respiratory and critical care medicine 2001;163(1):135-9.
2000: E L'Her; Mehran Monchi; B Joly; J Marichy; M Lejay; Jean-François Dhainaut
Helium-oxygen breathing in the early emergency care of acute severe asthma: a randomized pilot study.
European journal of emergency medicine : official journal of the European Society for Emergency Medicine 2000;7(4):271-5.
2000: Minou Adib-Conquy; Christophe Adrie; Pierre Moine; Karim Asehnoune; Catherine Fitting; M R Pinsky; Jean-François Dhainaut; Jean-Marc Cavaillon
NF-kappaB expression in mononuclear cells of patients with sepsis resembles that observed in lipopolysaccharide tolerance.
American journal of respiratory and critical care medicine 2000;162(5):1877-83.
2000: Jean-François Dhainaut; C Fisher
Concluding discussion of the Margaux Conference on Critical Illness: activation of the coagulation system in critical illnesses.
Critical care medicine 2000;28(9 Suppl):S88-9.
2000: Jean-François Dhainaut
Introduction to the Margaux Conference on Critical Illness: activation of the coagulation system in critical illnesses.
Critical care medicine 2000;28(9 Suppl):S1-3.
2000: Christophe Adrie; C Richter; Maria Bachelet; N Banzet; Dominique François; Anh Tuan Dinh-Xuan; Jean-François Dhainaut; Barbara S Polla; Marie-Jeanne Richard
Contrasting effects of NO and peroxynitrites on HSP70 expression and apoptosis in human monocytes.
American journal of physiology. Cell physiology 2000;279(2):C452-60.
2000: Gian-Luca Chelucci; Josette Dall'Ava-Santucci; Jean-François Dhainaut; A Chelucci; A Allegra; A Lockhart; Walter A Zin; J Milic-Emili
Association of PEEP with two different inflation volumes in ARDS patients: effects on passive lung deflation and alveolar recruitment.
Intensive care medicine 2000;26(7):870-7.
2000: Yann-Erick Claessens; Alain Cariou; Jean-Daniel Chiche; G Dauriat; Jean-François Dhainaut
L-Carnitine as a treatment of life-threatening lactic acidosis induced by nucleoside analogues.
AIDS (London, England) 2000;14(4):472-3.
2000: P Durand; Maria Bachelet; F Brunet; Marie-Jeanne Richard; Jean-François Dhainaut; Josette Dall'Ava; Barbara S Polla
Inducibility of the 70 kD heat shock protein in peripheral blood monocytes is decreased in human acute respiratory distress syndrome and recovers over time.
American journal of respiratory and critical care medicine 2000;161(1):286-92.
1999: Luc-Marie Joly; Mehran Monchi; Alain Cariou; Jean-Daniel Chiche; F Bellenfant; F Brunet; Jean-François Dhainaut
Effects of dobutamine on gastric mucosal perfusion and hepatic metabolism in patients with septic shock.
American journal of respiratory and critical care medicine 1999;160(6):1983-6.
1999: Jean-François Dhainaut; Nathalie Marin
[Controversies in septic shock].
La Revue du praticien 1999;49(5):461-3.
1999: Jean-François Dhainaut; Christophe Vinsonneau; D Journois
Hemofiltration and left ventricular function in sepsis: mechanisms and clinical implications.
Critical care medicine 1999;27(3):473-4.
1998: Alain Cariou; Mehran Monchi; Luc-Marie Joly; F Bellenfant; Yann-Erick Claessens; D Thébert; F Brunet; Jean-François Dhainaut
Noninvasive cardiac output monitoring by aortic blood flow determination: evaluation of the Sometec Dynemo-3000 system.
Critical care medicine 1998;26(12):2066-72.
1998: Jean-François Dhainaut; A Tenaillon; M Hemmer; P Damas; Y Le Tulzo; P Radermacher; M D Schaller; Jean-Pierre Sollet; Michel Wolff; L Holzapfel; F Zeni; J M Vedrinne; Florent de Vathaire; Margaret L Gourlay; P Guinot; J P Mira
Confirmatory platelet-activating factor receptor antagonist trial in patients with severe gram-negative bacterial sepsis: a phase III, randomized, double-blind, placebo-controlled, multicenter trial. BN 52021 Sepsis Investigator Group.
Critical care medicine 1998;26(12):1963-71.
1998: Alain Cariou; Mehran Monchi; Jean-François Dhainaut
Continuous cardiac output and mixed venous oxygen saturation monitoring.
Journal of critical care 1998;13(4):198-213.
1998: P Squara; Jean-François Dhainaut; Antonio Artigas; Jean Carlet
Hemodynamic profile in severe ARDS: results of the European Collaborative ARDS Study.
Intensive care medicine 1998;24(10):1018-28.
1998: Mehran Monchi; F Bellenfant; Alain Cariou; Luc-Marie Joly; D Thebert; Ivan Laurent; Jean-François Dhainaut; F Brunet
Early predictive factors of survival in the acute respiratory distress syndrome. A multivariate analysis.
American journal of respiratory and critical care medicine 1998;158(4):1076-81.
1998: Jean-Louis Vincent; Jean-François Dhainaut; C Perret; Peter Suter
Is the pulmonary artery catheter misused? A European view.
Critical care medicine 1998;26(7):1283-7.
1998: Mehran Monchi; D Thebert; Alain Cariou; F Bellenfant; Luc-Marie Joly; F Brunet; Jean-François Dhainaut
Clinical evaluation of the Abbott Qvue-OptiQ continuous cardiac output system in critically ill medical patients.
Journal of critical care 1998;13(2):91-5.
1997: Jean-François Dhainaut; M R Pinsky; S Nouria; F Slomka; Fabrice Brunet
Right ventricular function in human sepsis: a thermodilution study.
Chest 1997;112(4):1043-9.
1997: Steven M Opal; Charles J Fisher; Jean-François Dhainaut; Jean-Louis Vincent; R Brase; Stephen Lowry; J C Sadoff; Gus J Slotman; Howard Levy; R A Balk; M P Shelly; John P Pribble; J F LaBrecque; J Lookabaugh; H Donovan; H Dubin; R Baughman; J Norman; E DeMaria; K Matzel; Edward Abraham; Michael G Seneff
Confirmatory interleukin-1 receptor antagonist trial in severe sepsis: a phase III, randomized, double-blind, placebo-controlled, multicenter trial. The Interleukin-1 Receptor Antagonist Sepsis Investigator Group.
Critical care medicine 1997;25(7):1115-24.
1997: Christian Spaulding; Luc-Marie Joly; A Rosenberg; Mehran Monchi; S N Weber; Jean-François Dhainaut; P Carli
Immediate coronary angiography in survivors of out-of-hospital cardiac arrest.
The New England journal of medicine 1997;336(23):1629-33.
1996: Yves Le Tulzo; Mohsen Belghith; P Seguin; J Dall'Ava; Mehran Monchi; R Thomas; Jean-François Dhainaut
Reproducibility of thermodilution cardiac output determination in critically ill patients: comparison between bolus and continuous method.
Journal of clinical monitoring 1996;12(5):379-85.
1995: Jean-François Dhainaut; J L Vincent; C Richard; P Lejeune; Claude Martin; L Fierobe; S Stephens; U M Ney; M Sopwith
CDP571, a humanized antibody to human tumor necrosis factor-alpha: safety, pharmacokinetics, immune response, and influence of the antibody on cytokine concentrations in patients with septic shock. CPD571 Sepsis Study Group.
Critical care medicine 1995;23(9):1461-9.
1995: F Brunet; D Jeanbourquin; Mehran Monchi; J P Mira; L Fierobe; A Armaganidis; B Renaud; Mohsen Belghith; Semir Nouira; Jean-François Dhainaut
Should mechanical ventilation be optimized to blood gases, lung mechanics, or thoracic CT scan?
American journal of respiratory and critical care medicine 1995;152(2):524-30.
1995: L Fierobe; F Brunet; Jean-François Dhainaut; Mehran Monchi; Mohsen Belghith; J P Mira; Josette Dall'Ava-Santucci; Anh Tuan Dinh-Xuan
Effect of inhaled nitric oxide on right ventricular function in adult respiratory distress syndrome.
American journal of respiratory and critical care medicine 1995;151(5):1414-9.
1995: F Brunet; J P Mira; Jean-François Dhainaut; Josette Dall'Ava-Santucci
Efficacy of low-frequency positive-pressure ventilation-extracorporeal CO2 removal.
American journal of respiratory and critical care medicine 1995;151(4):1269-70.
1995: F Pochard; J J Lanore; Frank Bellivier; I Ferrand; J P Mira; Mohsen Belghith; F Brunet; Jean-François Dhainaut
Subjective psychological status of severely ill patients discharged from mechanical ventilation.
Clinical intensive care : international journal of critical & coronary care medicine 1995;6(2):57-61.
1994: P Squara; Didier Journois; J F Formela; B Schremmer; Jean-François Dhainaut; G Bleichner
Value of elementary, combined, and modeled hemodynamic variables.
Journal of critical care 1994;9(4):223-35.
1994: J P Mira; J E Fabre; Francisco Baigorri; J Coste; G Annat; Antonio Artigas; G Nitenberg; Jean-François Dhainaut
Lack of oxygen supply dependency in patients with severe sepsis. A study of oxygen delivery increased by military antishock trouser and dobutamine.
Chest 1994;106(5):1524-31.
1994: Jean-François Dhainaut; A Tenaillon; Yves Le Tulzo; Benoît Schlemmer; J P Solet; Michel Wolff; L Holzapfel; F Zeni; D Dreyfuss; J P Mira
Platelet-activating factor receptor antagonist BN 52021 in the treatment of severe sepsis: a randomized, double-blind, placebo-controlled, multicenter clinical trial. BN 52021 Sepsis Study Group.
Critical care medicine 1994;22(11):1720-8.
1994: J P Mira; Mehran Monchi; F Brunet; L Fierobe; Jean-François Dhainaut; Anh Tuan Dinh-Xuan
Lack of efficacy of inhaled nitric oxide in ARDS.
Intensive care medicine 1994;20(7):532.
1994: A Armaganidis; Jean-François Dhainaut; J L Billard; K Klouche; J P Mira; F Brunet; Anh Tuan Dinh-Xuan; Josette Dall'Ava-Santucci
Accuracy assessment for three fiberoptic pulmonary artery catheters for SvO2 monitoring.
Intensive care medicine 1994;20(7):484-8.
1994: F Brunet; J P Mira; Mohsen Belghith; Mehran Monchi; B Renaud; L Fierobe; I Hamy; Jean-François Dhainaut; Josette Dall'Ava-Santucci
Extracorporeal carbon dioxide removal technique improves oxygenation without causing overinflation.
American journal of respiratory and critical care medicine 1994;149(6):1557-62.
1994: Jean-François Dhainaut; J P Mira; F Brunet
Platelet-activating factor antagonists as therapeutic strategy in sepsis.
Progress in clinical and biological research 1994;388():277-93.
1993: F Brunet; Mohsen Belghith; J P Mira; J J Lanore; J F Vaxelaire; Josette Dall'Ava-Santucci; Jean-François Dhainaut
Extracorporeal carbon dioxide removal and low-frequency positive-pressure ventilation. Improvement in arterial oxygenation with reduction of risk of pulmonary barotrauma in patients with adult respiratory distress syndrome.
Chest 1993;104(3):889-98.
1993: G L Chelucci; J Dall' Ava-Santucci; Jean-François Dhainaut; A Chelucci; A Allegra; D Paccaly; F Brunet; J Milic-Emili; A Lockhart
Modelling of passive expiration in patients with adult respiratory distress syndrome.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1993;6(6):785-90.
1993: M Karmochkine; F Brunet; J J Lanore; M Belghit; J P Mira; Jean-François Dhainaut; J F Monsallier
Recovery from staphylococcal septicaemia in neutropenic patients without removal of the previously inserted central venous catheter.
The European journal of medicine 1993;2(3):143-7.
1993: T Giraud; Jean-François Dhainaut; J F Vaxelaire; T Joseph; Didier Journois; G Bleichner; Jean-Pierre Sollet; S Chevret; J F Monsallier
Iatrogenic complications in adult intensive care units: a prospective two-center study.
Critical care medicine 1993;21(1):40-51.
1993: E Mortier; Bertrand Godeau; P M Roy; Jean-François Dhainaut; Benoît Schlemmer; Jean Carlet; P Alquier; A Schaeffer; C Chastang
[Outcome of 161 patients with systemic diseases after their admission in intensive care unit].
La Revue de médecine interne / fondée ... par la Société nationale francaise de médecine interne 1993;14(10):973.
1992: Josette Dall'Ava-Santucci; F Brunet; Semir Nouira; A Armaganidis; Jean-François Dhainaut; J F Monsallier; A Lockhart
Passive partitioning of respiratory volumes and time constants in ventilated patients.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1992;5(8):1009-17.
1992: Bertrand Godeau; A Boudjadja; Jean-François Dhainaut; Benoît Schlemmer; C Chastang; F Brunet; Jean-Roger Le Gall
Outcome of patients with systemic rheumatic disease admitted to medical intensive care units.
Annals of the rheumatic diseases 1992;51(5):627-31.
1992: F Brunet; J P Mira; Mohsen Belghith; J J Lanore; S Schlumberger; P Toulon; Jean-François Dhainaut
Effects of aprotinin on hemorrhagic complications in ARDS patients during prolonged extracorporeal CO2 removal.
Intensive care medicine 1992;18(6):364-7.
1991: G L Chelucci; F Brunet; Josette Dall'Ava-Santucci; Jean-François Dhainaut; D Paccaly; A Armaganidis; J Milic-Emili; A Lockhart
A single-compartment model cannot describe passive expiration in intubated, paralysed humans.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1991;4(4):458-64.
1991: J J Lanore; F Brunet; F Pochard; Frank Bellivier; Jean-François Dhainaut; J F Vaxelaire; T Giraud; F Dreyfus; Didier Dreyfuss; Jean-Daniel Chiche
Hemodialysis for acute renal failure in patients with hematologic malignancies.
Critical care medicine 1991;19(3):346-51.
1991: T Giraud; Jean-François Dhainaut; B Schremmer; B Regnier; P Desjars; P Loirat; Didier Journois; J J Lanore
Adult overwhelming meningococcal purpura. A study of 35 cases, 1977-1989.
Archives of internal medicine 1991;151(2):310-6.
1990: Jean-François Dhainaut; F Brunet
Right ventricular performance in adult respiratory distress syndrome.
The European respiratory journal. Supplement 1990;11():490s-495s.
1990: Jean-François Dhainaut; E Ghannad; D Villemant; F Brunet; J Y Devaux; B Schremmer; P Squara; S Weber; J F Monsallier
Role of tricuspid regurgitation and left ventricular damage in the treatment of right ventricular infarction-induced low cardiac output syndrome.
The American journal of cardiology 1990;66(3):289-95.
1990: Josette Dall'Ava-Santucci; A Armaganidis; F Brunet; Jean-François Dhainaut; Semir Nouira; D Morisseau; A Lockhart
Mechanical effects of PEEP in patients with adult respiratory distress syndrome.
Journal of applied physiology (Bethesda, Md. : 1985) 1990;68(3):843-8.
1990: P Squara; Jean-François Dhainaut; B Schremmer; Jean-Pierre Sollet; G Bleichner
Decreased paradoxic pulse from increased venous return in severe asthma.
Chest 1990;97(2):377-83.
1990: B Schremmer; Jean-François Dhainaut
Heart failure in septic shock: effects of inotropic support.
Critical care medicine 1990;18(1 Pt 2):S49-55.
1990: B Schremmer; Jean-François Dhainaut
Regulation of myocardial oxygen delivery.
Intensive care medicine 1990;16 Suppl 2():S157-63.
1990: F Brunet; J J Lanore; Jean-François Dhainaut; François Dreyfus; J F Vaxelaire; Semir Nouira; T Giraud; A Armaganidis; J F Monsallier
Is intensive care justified for patients with haematological malignancies?
Intensive care medicine 1990;16(5):291-7.
1989: A Armaganidis; Jean-François Dhainaut
[Weaning from artificial respiration: value of continuous monitoring of mixed venous oxygen saturation].
Annales françaises d'anesthèsie et de rèanimation 1989;8(6):708-15.
1989: Jean-François Dhainaut; A Armaganidis
[Relation of oxygen transport and consumption. Role of impaired tissue uptake].
Annales françaises d'anesthèsie et de rèanimation 1989;8(6):677-81.
1989: Didier Journois; P Squara; Denis Safran; J F Formela; Jean-François Dhainaut
[Improvement of the prognostic value of O2 consumption (VO2) by comparison with the theoretical Sa value in states of shock].
Annales françaises d'anesthèsie et de rèanimation 1989;8 Suppl():R236.
1989: P Squara; Didier Journois; Denis Safran; D Chanu; Jean-François Dhainaut
[Description of a new hemodynamic index of prognostic value in septic subjects: PvO2/SaO2)].
Annales françaises d'anesthèsie et de rèanimation 1989;8 Suppl():R235.
1989: Semir Nouira; Jean-François Dhainaut; F Brunet; A Armaganidis; T Giraud; M T Garrauste; G Corsia; B Schremmer; J F Monsallier
[Septic shock: hemodynamic effects of noradrenaline and a noradrenaline-dopexamine combination].
Annales françaises d'anesthèsie et de rèanimation 1989;8 Suppl():R234.
1989: F Brunet; A Armaganidis; Jean-François Dhainaut; Semir Nouira; J J Lanore; J Vaxelaire; T Giraud; Josette Dall'Ava-Santucci; J F Monsallier
[Respiration at low frequency associated with extracorporeal purification of CO2 in the treatment of ARDS: methodology and first results].
Annales françaises d'anesthèsie et de rèanimation 1989;8 Suppl():R257.
1989: F Brunet; A Armaganidis; Josette Dall'Ava-Santucci; Semir Nouira; J Vaxelaire; T Giraud; J J Lanore; Jean-François Dhainaut; J F Monsallier
[Respiration at base frequency associated with extracorporeal purification of CO2: role of oxygen output by the intratracheal catheter].
Annales françaises d'anesthèsie et de rèanimation 1989;8 Suppl():R256.
1988: G Lefevre; Jean-François Dhainaut; F Tallet; M F Huyghebaert; J Yonger; J F Monsallier; D Raichvarg
Individual free fatty acids and lactate uptake in the human heart during severe sepsis.
Annals of clinical biochemistry 1988;25 ( Pt 5)():546-51.
1988: Jean-François Dhainaut; J J Lanore; J M de Gournay; M F Huyghebaert; F Brunet; D Villemant; J F Monsallier
Right ventricular dysfunction in patients with septic shock.
Intensive care medicine 1988;14 Suppl 2():488-91.
1988: F Brunet; Jean-François Dhainaut; J Y Devaux; M F Huyghebaert; D Villemant; J F Monsallier
Right ventricular performance in patients with acute respiratory failure.
Intensive care medicine 1988;14 Suppl 2():474-7.
1988: Jean-François Dhainaut; J J Lanore; J M de Gournay; M F Huyghebaert; F Brunet; A Carli; J F Monsallier
Right ventricular dysfunction in human septic shock.
Progress in clinical and biological research 1988;264():343-8.
1988: Josette Dall'Ava-Santucci; A Armaganidis; F Brunet; Jean-François Dhainaut; G L Chelucci; J F Monsallier; A Lockhart
Causes of error of respiratory pressure-volume curves in paralyzed subjects.
Journal of applied physiology (Bethesda, Md. : 1985) 1988;64(1):42-9.
1988: Jean-François Dhainaut
[Use of new inotropic agents in the treatment of acute cardiac failure].
Annales françaises d'anesthèsie et de rèanimation 1988;7(2):97-104.
1987: Jean-François Dhainaut; M F Huyghebaert
[Coronary circulation and myocardial metabolism in septic shock. Effects of a dobutamine-dopamine combination].
Revue médicale de la Suisse romande 1987;107(6):477-83.
1987: Jean-François Dhainaut; M F Huyghebaert; J F Monsallier; G Lefevre; Josette Dall'Ava-Santucci; F Brunet; D Villemant; A Carli; D Raichvarg
Coronary hemodynamics and myocardial metabolism of lactate, free fatty acids, glucose, and ketones in patients with septic shock.
Circulation 1987;75(3):533-41.
1987: Jean-François Dhainaut; F Brunet; J F Monsallier; D Villemant; J Y Devaux; M Konno; J M De Gournay; A Armaganidis; G Iotti; M F Huyghebaert
Bedside evaluation of right ventricular performance using a rapid computerized thermodilution method.
Critical care medicine 1987;15(2):148-52.
1986: Jean-François Dhainaut; J Y Devaux; J F Monsallier; F Brunet; D Villemant; M F Huyghebaert
Mechanisms of decreased left ventricular preload during continuous positive pressure ventilation in ARDS.
Chest 1986;90(1):74-80.
1985: M F Huyghebaert; Jean-François Dhainaut; J F Monsallier; Benoît Schlemmer
Bicarbonate hemodialysis of patients with acute renal failure and severe sepsis.
Critical care medicine 1985;13(10):840-3.
1984: Jean-François Dhainaut; Benoît Schlemmer; J F Monsallier; M F Huyghebaert; F Brunet; D Villemant; A Carli
Oxygen consumption during septic shock. Effects of inotropic drugs.
Archives internationales de physiologie et de biochimie 1984;92(4):S57-64.
1983: M F Huyghebaert; Jean-François Dhainaut; V Fourestie; J Bons; Benoît Schlemmer; J F Monsallier
[Improvement of dialysis tolerance in patients with severe infections using a bicarbonate dialysate].
Néphrologie 1983;4(4-5):245-7.
1982: Jean-François Dhainaut; C Bricard; F J Monsallier; O Salmon; J Bons; V Fourestie; Benoît Schlemmer; A Carli
Left ventricular contractility using isovolumic phase indices during PEEP in ARDS patients.
Critical care medicine 1982;10(10):631-5.
1982: Jean-François Dhainaut; Y Huet; A Kahan; C Bricard; E Neveux; J Y Dallot; J Bachet; A Carli; F J Monsallier
Acute myocardial failure during Yersinia enterocolitica infection.
Intensive care medicine 1982;8(1):51-3.