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Padmaja Dhanasekaran

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TOP 3
Emi Adachi; Kenichi Akaji; Padmaja Dhanasekaran; Hiroyuki Kawashima; Sissel Lund-Katz; Chiharu Mizuguchi; Kohjiro Nagao; Hiroyuki Nakajima; Michael C Phillips; Hiroyuki Saito
Dual role of an N-terminal amyloidogenic mutation in apolipoprotein A-I: destabilization of helix bundle and enhancement of fibril formation.
Palaniappan S Chetty; Padmaja Dhanasekaran; Walter Englander; Sissel Lund-Katz; Leland Mayne; Maki Ohshiro; Hiroyuki Saito; Michael C Phillips
Effects of the Iowa and Milano mutations on apolipoprotein A-I structure and dynamics determined by hydrogen exchange and mass spectrometry.
Chiharu Mizuguchi; Margaret Nickel; Michael C Phillips; Padmaja Dhanasekaran; Mami Hata; Sissel Lund-Katz; Hiroyuki Saito
Fluorescence analysis of the lipid binding-induced conformational change of apolipoprotein E4.

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All Publications

2013: Emi Adachi; Kenichi Akaji; Padmaja Dhanasekaran; Hiroyuki Kawashima; Sissel Lund-Katz; Chiharu Mizuguchi; Kohjiro Nagao; Hiroyuki Nakajima; Michael C Phillips; Hiroyuki Saito
Dual role of an N-terminal amyloidogenic mutation in apolipoprotein A-I: destabilization of helix bundle and enhancement of fibril formation.
The Journal of biological chemistry 2013;288(4):2848-56.
2012: Palaniappan S Chetty; Padmaja Dhanasekaran; Walter Englander; Sissel Lund-Katz; Leland Mayne; Maki Ohshiro; Hiroyuki Saito; Michael C Phillips
Effects of the Iowa and Milano mutations on apolipoprotein A-I structure and dynamics determined by hydrogen exchange and mass spectrometry.
Biochemistry 2012;51(44):8993-9001.
2012: Chiharu Mizuguchi; Margaret Nickel; Michael C Phillips; Padmaja Dhanasekaran; Mami Hata; Sissel Lund-Katz; Hiroyuki Saito
Fluorescence analysis of the lipid binding-induced conformational change of apolipoprotein E4.
Biochemistry 2012;51(28):5580-8.
2012: Nicholas N Lyssenko; David Nguyen; Margaret Nickel; Palaniappan Sevugan Chetty; Padmaja Dhanasekaran; Mami Hata; Sissel Lund-Katz; Hiroyuki Saito; Michael C Phillips
Influence of C-terminal α-helix hydrophobicity and aromatic amino acid content on apolipoprotein A-I functionality.
Biochimica et biophysica acta 2012;1821(3):456-63.
2011: Masafumi Tanaka; Padmaja Dhanasekaran; David Nguyen; Margaret Nickel; Yuki Takechi; Sissel Lund-Katz; Michael C Phillips; Hiroyuki Saito
Influence of N-terminal helix bundle stability on the lipid-binding properties of human apolipoprotein A-I.
Biochimica et biophysica acta 2011;1811(1):25-30.
2010: Momoe Kono; Toshitaka Tanaka; Masafumi Tanaka; Charulatha Vedhachalam; Palaniappan S Chetty; David Nguyen; Padmaja Dhanasekaran; Sissel Lund-Katz; Michael C Phillips; Hiroyuki Saito
Disruption of the C-terminal helix by single amino acid deletion is directly responsible for impaired cholesterol efflux ability of apolipoprotein A-I Nichinan.
Journal of lipid research 2010;51(4):809-18.
2009: Mao Koyama; Masafumi Tanaka; Padmaja Dhanasekaran; Sissel Lund-Katz; Michael C Phillips; Hiroyuki Saito
Interaction between the N- and C-terminal domains modulates the stability and lipid binding of apolipoprotein A-I.
Biochemistry 2009;48(11):2529-37.
2008: Momoe Kono; Yusuke Okumura; Masafumi Tanaka; David Nguyen; Padmaja Dhanasekaran; Sissel Lund-Katz; Michael C Phillips; Hiroyuki Saito
Conformational flexibility of the N-terminal domain of apolipoprotein a-I bound to spherical lipid particles.
Biochemistry 2008;47(43):11340-7.
2008: Takaaki Sakamoto; Masafumi Tanaka; Charulatha Vedhachalam; Margaret Nickel; David Nguyen; Padmaja Dhanasekaran; Michael C Phillips; Sissel Lund-Katz; Hiroyuki Saito
Contributions of the carboxyl-terminal helical segment to the self-association and lipoprotein preferences of human apolipoprotein E3 and E4 isoforms.
Biochemistry 2008;47(9):2968-77.
2008: Masafumi Tanaka; Mao Koyama; Padmaja Dhanasekaran; David Nguyen; Margaret Nickel; Sissel Lund-Katz; Hiroyuki Saito; Michael C Phillips
Influence of tertiary structure domain properties on the functionality of apolipoprotein A-I.
Biochemistry 2008;47(7):2172-80.
2007: Charulatha Vedhachalam; Phu T Duong; Margaret Nickel; David Nguyen; Padmaja Dhanasekaran; Hiroyuki Saito; George H Rothblat; Sissel Lund-Katz; Michael C Phillips
Mechanism of ATP-binding cassette transporter A1-mediated cellular lipid efflux to apolipoprotein A-I and formation of high density lipoprotein particles.
The Journal of biological chemistry 2007;282(34):25123-30.
2006: Masafumi Tanaka; Padmaja Dhanasekaran; David Nguyen; Shinya Ohta; Sissel Lund-Katz; Michael C Phillips; Hiroyuki Saito
Contributions of the N- and C-terminal helical segments to the lipid-free structure and lipid interaction of apolipoprotein A-I.
Biochemistry 2006;45(34):10351-8.
2006: Masafumi Tanaka; Charulatha Vedhachalam; Takaaki Sakamoto; Padmaja Dhanasekaran; Michael C Phillips; Sissel Lund-Katz; Hiroyuki Saito
Effect of carboxyl-terminal truncation on structure and lipid interaction of human apolipoprotein E4.
Biochemistry 2006;45(13):4240-7.
2005: Masafumi Tanaka; Hiroyuki Saito; Padmaja Dhanasekaran; Suzanne Wehrli; Tetsurou Handa; Sissel Lund-Katz; Michael C Phillips
Effects of the core lipid on the energetics of binding of ApoA-I to model lipoprotein particles of different sizes.
Biochemistry 2005;44(31):10689-95.
2005: Miho Futamura; Padmaja Dhanasekaran; Tetsurou Handa; Michael C Phillips; Sissel Lund-Katz; Hiroyuki Saito
Two-step mechanism of binding of apolipoprotein E to heparin: implications for the kinetics of apolipoprotein E-heparan sulfate proteoglycan complex formation on cell surfaces.
The Journal of biological chemistry 2005;280(7):5414-22.
2004: Charulatha Vedhachalam; Lijuan Liu; Margaret Nickel; Padmaja Dhanasekaran; G M Anantharamaiah; Sissel Lund-Katz; George H Rothblat; Michael C Phillips
Influence of ApoA-I structure on the ABCA1-mediated efflux of cellular lipids.
The Journal of biological chemistry 2004;279(48):49931-9.
2004: Hiroyuki Saito; Padmaja Dhanasekaran; David Nguyen; Els Deridder; Paul Holvoet; Sissel Lund-Katz; Michael C Phillips
Alpha-helix formation is required for high affinity binding of human apolipoprotein A-I to lipids.
The Journal of biological chemistry 2004;279(20):20974-81.
2004: Vasanthy Narayanaswami; J Nicholas Maiorano; Padmaja Dhanasekaran; Robert O Ryan; Michael C Phillips; Sissel Lund-Katz; W Sean Davidson
Helix orientation of the functional domains in apolipoprotein e in discoidal high density lipoprotein particles.
The Journal of biological chemistry 2004;279(14):14273-9.
2004: Stephen T Thuahnai; Sissel Lund-Katz; Padmaja Dhanasekaran; Margarita de la Llera-Moya; Margery A Connelly; David L Williams; George H Rothblat; Michael C Phillips
Scavenger receptor class B type I-mediated cholesteryl ester-selective uptake and efflux of unesterified cholesterol. Influence of high density lipoprotein size and structure.
The Journal of biological chemistry 2004;279(13):12448-55.
2003: Lijuan Liu; Anna E Bortnick; Margaret Nickel; Padmaja Dhanasekaran; Papasani V Subbaiah; Sissel Lund-Katz; George H Rothblat; Michael C Phillips
Effects of apolipoprotein A-I on ATP-binding cassette transporter A1-mediated efflux of macrophage phospholipid and cholesterol: formation of nascent high density lipoprotein particles.
The Journal of biological chemistry 2003;278(44):42976-84.
2003: Hiroyuki Saito; Padmaja Dhanasekaran; Faye Baldwin; Karl H Weisgraber; Michael C Phillips; Sissel Lund-Katz
Effects of polymorphism on the lipid interaction of human apolipoprotein E.
The Journal of biological chemistry 2003;278(42):40723-9.
2003: Hiroyuki Saito; Padmaja Dhanasekaran; David Nguyen; Paul Holvoet; Sissel Lund-Katz; Michael C Phillips
Domain structure and lipid interaction in human apolipoproteins A-I and E, a general model.
The Journal of biological chemistry 2003;278(26):23227-32.
2003: Hiroyuki Saito; Padmaja Dhanasekaran; David Nguyen; Faye Baldwin; Karl H Weisgraber; Suzanne Wehrli; Michael C Phillips; Sissel Lund-Katz
Characterization of the heparin binding sites in human apolipoprotein E.
The Journal of biological chemistry 2003;278(17):14782-7.
2002: Mark L Segall; Padmaja Dhanasekaran; Faye Baldwin; G M Anantharamaiah; Karl H Weisgraber; Michael C Phillips; Sissel Lund-Katz
Influence of apoE domain structure and polymorphism on the kinetics of phospholipid vesicle solubilization.
Journal of lipid research 2002;43(10):1688-700.
2001: Hiroyuki Saito; Padmaja Dhanasekaran; Faye Baldwin; Karl H Weisgraber; Sissel Lund-Katz; Michael C Phillips
Lipid binding-induced conformational change in human apolipoprotein E. Evidence for two lipid-bound states on spherical particles.
The Journal of biological chemistry 2001;276(44):40949-54.
2000: Sissel Lund-Katz; Mohamed Zaiou; Suzanne Wehrli; Padmaja Dhanasekaran; Faye Baldwin; Karl H Weisgraber; Michael C Phillips
Effects of lipid interaction on the lysine microenvironments in apolipoprotein E.
The Journal of biological chemistry 2000;275(44):34459-64.