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Roberto Di Lauro

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Immacolata Porreca; Elena De Felice; Roberto Di Lauro; Henrik Fagman; Paolo Sordino
Zebrafish bcl2l is a survival factor in thyroid development.
Mario De Felice; Roberto Di Lauro
Minireview: Intrinsic and extrinsic factors in thyroid gland development: an update.
Daniela Frezzetti; Ola Nilsson; Lucio Nitsch; Carla Reale; Marzia Scarfò; Gaetano Calì; Gabriella De Vita; Henrik Fagman; Roberto Di Lauro
The microRNA-processing enzyme Dicer is essential for thyroid function.

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All Publications

2012: Immacolata Porreca; Elena De Felice; Roberto Di Lauro; Henrik Fagman; Paolo Sordino
Zebrafish bcl2l is a survival factor in thyroid development.
Developmental biology 2012;366(2):142-52.
2011: Mario De Felice; Roberto Di Lauro
Minireview: Intrinsic and extrinsic factors in thyroid gland development: an update.
Endocrinology 2011;152(8):2948-56.
2011: Daniela Frezzetti; Ola Nilsson; Lucio Nitsch; Carla Reale; Marzia Scarfò; Gaetano Calì; Gabriella De Vita; Henrik Fagman; Roberto Di Lauro
The microRNA-processing enzyme Dicer is essential for thyroid function.
PloS one 2011;6(11):e27648.
2011: Daniel Silberschmidt; Alina Rodriguez-Mallon; Prathiba Mithboakar; Gaetano Calì; Elena Amendola; Remo Sanges; Mariastella Zannini; Marzia Scarfò; Pasquale De Luca; Lucio Nitsch; Roberto Di Lauro; Mario De Felice
In vivo role of different domains and of phosphorylation in the transcription factor Nkx2-1.
BMC developmental biology 2011;11():9.
2010: Elena Amendola; Remo Sanges; Antonella Galvan; Nina Dathan; Giacomo Manenti; Giuseppe Ferrandino; Francesca Maria Alvino; Tina Di Palma; Marzia Scarfò; Mariastella Zannini; Tommaso A Dragani; Mario De Felice; Roberto Di Lauro
A locus on mouse chromosome 2 is involved in susceptibility to congenital hypothyroidism and contains an essential gene expressed in thyroid.
Endocrinology 2010;151(4):1948-58.
2009: Maria Giuseppina Baratta; Immacolata Porreca; Roberto Di Lauro
Oncogenic ras blocks the cAMP pathway and dedifferentiates thyroid cells via an impairment of pax8 transcriptional activity.
Molecular endocrinology (Baltimore, Md.) 2009;23(6):838-48.
2008: Minh D To; Christine E Wong; Anthony N Karnezis; Reyno Del Rosario; Roberto Di Lauro; Allan Balmain
Kras regulatory elements and exon 4A determine mutation specificity in lung cancer.
Nature genetics 2008;40(10):1240-4.
2008: Francesco Errico; Emanuela Santini; Sara Migliarini; Anders Borgkvist; Diego Centonze; Valentina Nasti; Mario Carta; Valentina De Chiara; Chiara Prosperetti; Daniela Spano; Denis Herve; Massimo Pasqualetti; Roberto Di Lauro; Gilberto Fisone; Alessandro Usiello
The GTP-binding protein Rhes modulates dopamine signalling in striatal medium spiny neurons.
Molecular and cellular neurosciences 2008;37(2):335-45.
2008: Francesco Errico; Robert Nisticò; Giuseppe Palma; Mauro Federici; Andrea Affuso; Elisa Brilli; Enza Topo; Diego Centonze; Giorgio Bernardi; Yuri Bozzi; Antimo D'Aniello; Roberto Di Lauro; Nicola B Mercuri; Alessandro Usiello
Increased levels of d-aspartate in the hippocampus enhance LTP but do not facilitate cognitive flexibility.
Molecular and cellular neurosciences 2008;37(2):236-46.
2007: Gaetano Calì; Mariastella Zannini; Patrizia Rubini; Carlo Tacchetti; Barbara D'Andrea; Andrea Affuso; Tim Wintermantel; Oreda Boussadia; Daniela Terracciano; Daniel Silberschmidt; Elena Amendola; Mario De Felice; Günther Schütz; Rolf Kemler; Roberto Di Lauro; Lucio Nitsch
Conditional inactivation of the E-cadherin gene in thyroid follicular cells affects gland development but does not impair junction formation.
Endocrinology 2007;148(6):2737-46.
2007: Mario De Felice; Roberto Di Lauro
Murine models for the study of thyroid gland development.
Endocrine development 2007;10():1-14.
2006: Lucia Pellizzari; Cinzia Puppin; Laura Mariuzzi; Francesca Saro; Maura Pandolfi; Roberto Di Lauro; Carlo Alberto Beltrami; Giuseppe Damante
PAX8 expression in human bladder cancer.
Oncology reports 2006;16(5):1015-20.
2006: Barbara D'Andrea; Roberto Iacone; Tina Di Palma; Roberto Nitsch; Maria Giuseppina Baratta; Lucio Nitsch; Roberto Di Lauro; Mariastella Zannini
Functional inactivation of the transcription factor Pax8 through oligomerization chain reaction.
Molecular endocrinology (Baltimore, Md.) 2006;20(8):1810-24.
2006: Francesco Errico; Maria Teresa Pirro; Andrea Affuso; Patrizia Spinelli; Mario De Felice; Antimo D'Aniello; Roberto Di Lauro
A physiological mechanism to regulate D-aspartic acid and NMDA levels in mammals revealed by D-aspartate oxidase deficient mice.
Gene 2006;374():50-7.
2006: Monica Dentice; Viviana Cordeddu; Annamaria Rosica; Alfonso Massimiliano Ferrara; Libero Santarpia; Domenico Salvatore; Luca Chiovato; Anna Perri; Lidia Moschini; Cristina Fazzini; Antonella Olivieri; Pietro Costa; Vera Stoppioni; Mariangiola Baserga; Mario De Felice; Mariella Sorcini; Gianfranco Fenzi; Roberto Di Lauro; Marco Tartaglia; Paolo Emidio Macchia
Missense mutation in the transcription factor NKX2-5: a novel molecular event in the pathogenesis of thyroid dysgenesis.
The Journal of clinical endocrinology and metabolism 2006;91(4):1428-33.
2005: Elena Amendola; Pasquale De Luca; Paolo Emidio Macchia; Daniela Terracciano; Annamaria Rosica; Gennaro Chiappetta; Shioko Kimura; Ahmed Mansouri; Andrea Affuso; Claudio Arra; Vincenzo Macchia; Roberto Di Lauro; Mario De Felice
A mouse model demonstrates a multigenic origin of congenital hypothyroidism.
Endocrinology 2005;146(12):5038-47.
2005: Monica Dentice; Cristina Luongo; Andrea Elefante; Raffaele Ambrosio; Salvatore Salzano; Mariastella Zannini; Roberto Nitsch; Roberto Di Lauro; Guido Rossi; Gianfranco Fenzi; Domenico Salvatore
Pendrin is a novel in vivo downstream target gene of the TTF-1/Nkx-2.1 homeodomain transcription factor in differentiated thyroid cells.
Molecular and cellular biology 2005;25(22):10171-82.
2005: Nicoletta Potenza; Carmine Vecchione; Antonella Notte; Assunta De Rienzo; Annamaria Rosica; Lisa Bauer; Andrea Affuso; Mario De Felice; Tommaso Russo; Roberta Poulet; Giuseppe Cifelli; Gabriella De Vita; Giuseppe Lembo; Roberto Di Lauro
Replacement of K-Ras with H-Ras supports normal embryonic development despite inducing cardiovascular pathology in adult mice.
EMBO reports 2005;6(5):432-7.
2005: Gabriella De Vita; Lisa Bauer; Vania M Correa da Costa; Mario De Felice; Maria Giuseppina Baratta; Marta De Menna; Roberto Di Lauro
Dose-dependent inhibition of thyroid differentiation by RAS oncogenes.
Molecular endocrinology (Baltimore, Md.) 2005;19(1):76-89.
2004: Rosanna Parlato; Annamaria Rosica; Alina Rodriguez-Mallon; Andrea Affuso; Maria Pia Postiglione; Claudio Arra; Ahmed Mansouri; Shioko Kimura; Roberto Di Lauro; Mario De Felice
An integrated regulatory network controlling survival and migration in thyroid organogenesis.
Developmental biology 2004;276(2):464-75.
2004: J T Chun; V Di Dato; Barbara D'Andrea; Mariastella Zannini; Roberto Di Lauro
The CRE-like element inside the 5'-upstream region of the rat sodium/iodide symporter gene interacts with diverse classes of b-Zip molecules that regulate transcriptional activities through strong synergy with Pax-8.
Molecular endocrinology (Baltimore, Md.) 2004;18(11):2817-29.
2004: Mario De Felice; Roberto Di Lauro
Thyroid development and its disorders: genetics and molecular mechanisms.
Endocrine reviews 2004;25(5):722-46.
2004: Mario De Felice; Maria Pia Postiglione; Roberto Di Lauro
Minireview: thyrotropin receptor signaling in development and differentiation of the thyroid gland: insights from mouse models and human diseases.
Endocrinology 2004;145(9):4062-7.
2004: Daniela Spano; Igor Branchi; Annamaria Rosica; Maria Teresa Pirro; Antonio Riccio; Pratibha Mithbaokar; Andrea Affuso; Claudio Arra; Patrizia Campolongo; Daniela Terracciano; Vincenzo Macchia; Juan Bernal; Enrico Alleva; Roberto Di Lauro
Rhes is involved in striatal function.
Molecular and cellular biology 2004;24(13):5788-96.
2003: Albertina Fanelli; Gabriella Lania; Antonietta Spagnuolo; Roberto Di Lauro
Interplay of negative and positive signals controls endoderm-specific expression of the ascidian Cititf1 gene promoter.
Developmental biology 2003;263(1):12-23.
2003: Antonietta Spagnuolo; Filomena Ristoratore; Anna Di Gregorio; Francesco Aniello; Margherita Branno; Roberto Di Lauro
Unusual number and genomic organization of Hox genes in the tunicate Ciona intestinalis.
Gene 2003;309(2):71-9.
2003: Roberto Di Lauro
Molecular abnormalities of organogenesis and differentiation of the thyroid gland.
Annales d'endocrinologie 2003;64(1):53.
2003: Tina Di Palma; Roberto Nitsch; Anna Mascia; Lucio Nitsch; Roberto Di Lauro; Mariastella Zannini
The paired domain-containing factor Pax8 and the homeodomain-containing factor TTF-1 directly interact and synergistically activate transcription.
The Journal of biological chemistry 2003;278(5):3395-402.
2002: Maria Pia Postiglione; Rosanna Parlato; Alina Rodriguez-Mallon; Annamaria Rosica; Pratibha Mithbaokar; M Maresca; Russell C Marians; terry Davies; Mariastella Zannini; Mario De Felice; Roberto Di Lauro
Role of the thyroid-stimulating hormone receptor signaling in development and differentiation of the thyroid gland.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(24):15462-7.
2002: Nina Dathan; Rosanna Parlato; Annamaria Rosica; Mario De Felice; Roberto Di Lauro
Distribution of the titf2/foxe1 gene product is consistent with an important role in the development of foregut endoderm, palate, and hair.
Developmental dynamics : an official publication of the American Association of Anatomists 2002;224(4):450-6.
2002: Antonietta Spagnuolo; Roberto Di Lauro
Cititf1 and endoderm differentiation in Ciona intestinalis.
Gene 2002;287(1-2):115-9.
2002: Rosanna Parlato; Annamaria Rosica; Vincenzo Cuccurullo; Luigi Mansi; Paolo Emidio Macchia; James D Owens; J Frederic Mushinski; Mario De Felice; Robert F Bonner; Roberto Di Lauro
A preservation method that allows recovery of intact RNA from tissues dissected by laser capture microdissection.
Analytical biochemistry 2002;300(2):139-45.
2002: Anna Mascia; Lucio Nitsch; Roberto Di Lauro; Mariastella Zannini
Hormonal control of the transcription factor Pax8 and its role in the regulation of thyroglobulin gene expression in thyroid cells.
The Journal of endocrinology 2002;172(1):163-76.
2001: Caterina Missero; MT Pirro; S Simeone; M Pischetola; Roberto Di Lauro
The DNA glycosylase T:G mismatch-specific thymine DNA glycosylase represses thyroid transcription factor-1-activated transcription.
The Journal of biological chemistry 2001;276(36):33569-75.
2001: G Cobellis; Caterina Missero; Barbara Simionati; G Valle; Roberto Di Lauro
Immediate early genes induced by H-Ras in thyroid cells.
Oncogene 2001;20(18):2281-90.
2001: J T Chun; Roberto Di Lauro
Characterization of the upstream enhancer of the rat sodium/iodide symporter gene.
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 2001;109(1):23-6.
2001: Giuseppe Damante; Gianluca Tell; Roberto Di Lauro
A unique combination of transcription factors controls differentiation of thyroid cells.
Progress in nucleic acid research and molecular biology 2001;66():307-56.
2000: A Caracciolo; Anna Di Gregorio; Francesco Aniello; Roberto Di Lauro; Margherita Branno
Identification and developmental expression of three Distal-less homeobox containing genes in the ascidian Ciona intestinalis.
Mechanisms of development 2000;99(1-2):173-6.
2000: Marina Pasca di Magliano; Roberto Di Lauro; Mariastella Zannini
Pax8 has a key role in thyroid cell differentiation.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(24):13144-9.
2000: G Procaccini; M Pischetola; Roberto Di Lauro
Isolation and characterization of microsatellite loci in the ascidian Ciona intestinalis (L.).
Molecular ecology 2000;9(11):1924-6.
2000: L Perrone; Marina Pasca di Magliano; Mariastella Zannini; Roberto Di Lauro
The thyroid transcription factor 2 (TTF-2) is a promoter-specific DNA-binding independent transcriptional repressor.
Biochemical and biophysical research communications 2000;275(1):203-8.
2000: Caterina Missero; MT Pirro; Roberto Di Lauro
Multiple ras downstream pathways mediate functional repression of the homeobox gene product TTF-1.
Molecular and cellular biology 2000;20(8):2783-93.
1999: Filomena Ristoratore; Antonietta Spagnuolo; Francesco Aniello; Margherita Branno; F Fabbrini; Roberto Di Lauro
Expression and functional analysis of Cititf1, an ascidian NK-2 class gene, suggest its role in endoderm development.
Development (Cambridge, England) 1999;126(22):5149-59.
1999: Gianluca Tell; Lucia Pellizzari; G Esposito; Carlo Pucillo; Paolo Emidio Macchia; Roberto Di Lauro; Giuseppe Damante
Structural defects of a Pax8 mutant that give rise to congenital hypothyroidism.
The Biochemical journal 1999;341 ( Pt 1)():89-93.
1999: Paolo Emidio Macchia; Mario De Felice; Roberto Di Lauro
Molecular genetics of congenital hypothyroidism.
Current opinion in genetics & development 1999;9(3):289-94.
1999: Paolo Emidio Macchia; M G Mattei; Paola Lapi; Gianfranco Fenzi; Roberto Di Lauro
Cloning, chromosomal localization and identification of polymorphisms in the human thyroid transcription factor 2 gene (TITF2).
Biochimie 1999;81(5):433-40.
1999: M Ohno; Mariastella Zannini; O Levy; Nancy Carrasco; Roberto Di Lauro
The paired-domain transcription factor Pax8 binds to the upstream enhancer of the rat sodium/iodide symporter gene and participates in both thyroid-specific and cyclic-AMP-dependent transcription.
Molecular and cellular biology 1999;19(3):2051-60.
1999: L Perrone; G Tell; Roberto Di Lauro
Calreticulin enhances the transcriptional activity of thyroid transcription factor-1 by binding to its homeodomain.
The Journal of biological chemistry 1999;274(8):4640-5.
1998: G Cobellis; Caterina Missero; Roberto Di Lauro
Concomitant activation of MEK-1 and Rac-1 increases the proliferative potential of thyroid epithelial cells, without affecting their differentiation.
Oncogene 1998;17(16):2047-57.
1998: Eleonora Carosa; Albertina Fanelli; Salvatore Ulisse; Roberto Di Lauro; Joseph Edward Rall; Emmanuele Jannini
Ciona intestinalis nuclear receptor 1: a member of steroid/thyroid hormone receptor family.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(19):11152-7.
1998: Mario De Felice; C Ovitt; E Biffali; Alina Rodriguez-Mallon; Claudio Arra; Konstantinos Anastassiadis; Paolo Emidio Macchia; M G Mattei; Angela Mariano; H Schöler; Vincenzo Macchia; Roberto Di Lauro
A mouse model for hereditary thyroid dysgenesis and cleft palate.
Nature genetics 1998;19(4):395-8.
1998: Amelia Casamassimi; Maria Giuseppina Miano; Antonio Porcellini; Gabriella De Vita; Filomena de Nigris; Mariastella Zannini; Roberto Di Lauro; Tommaso Russo; VE Avvedimento; Alfredo Fusco
p53 genes mutated in the DNA binding site or at a specific COOH-terminal site exert divergent effects on thyroid cell growth and differentiation.
Cancer research 1998;58(13):2888-94.
1998: Juan A Velasco; A Acebrón; Mariastella Zannini; Jorge Martín-Pérez; Roberto Di Lauro; Pilar Santisteban
Ha-ras interference with thyroid cell differentiation is associated with a down-regulation of thyroid transcription factor-1 phosphorylation.
Endocrinology 1998;139(6):2796-802.
1998: Caterina Missero; G Cobellis; M De Felice; Roberto Di Lauro
Molecular events involved in differentiation of thyroid follicular cells.
Molecular and cellular endocrinology 1998;140(1-2):37-43.
1998: Paolo Emidio Macchia; Paola Lapi; Heiko Krude; MT Pirro; Caterina Missero; Luca Chiovato; Abdallah Souabni; Mariangiola Baserga; Vittorio Tassi; Aldo Pinchera; Gianfranco Fenzi; Annette Grüters; Meinrad Busslinger; Roberto Di Lauro
PAX8 mutations associated with congenital hypothyroidism caused by thyroid dysgenesis.
Nature genetics 1998;19(1):83-6.
1998: M Gionti; Filomena Ristoratore; Anna Di Gregorio; Francesco Aniello; Margherita Branno; Roberto Di Lauro
Cihox5, a new Ciona intestinalis Hox-related gene, is involved in regionalization of the spinal cord.
Development genes and evolution 1998;207(8):515-23.
1998: L Aurisicchio; Roberto Di Lauro; Mariastella Zannini
Identification of the thyroid transcription factor-1 as a target for rat MST2 kinase.
The Journal of biological chemistry 1998;273(3):1477-82.
1998: Gabriella De Vita; Mariastella Zannini; Anna Maria Cirafici; Rosa Marina Melillo; Roberto Di Lauro; Alfredo Fusco; Massimo Santoro
Expression of the RET/PTC1 oncogene impairs the activity of TTF-1 and Pax-8 thyroid transcription factors.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1998;9(1):97-103.
1997: Anna Mascia; Mario De Felice; Concetta Lipardi; R Gentile; Gaetano Calì; Mariastella Zannini; Roberto Di Lauro; Lucio Nitsch
Transfection of TTF-1 gene induces thyroglobulin gene expression in undifferentiated FRT cells.
Biochimica et biophysica acta 1997;1354(2):171-81.
1997: L Ortiz; Mariastella Zannini; Roberto Di Lauro; Pilar Santisteban
Transcriptional control of the forkhead thyroid transcription factor TTF-2 by thyrotropin, insulin, and insulin-like growth factor I.
The Journal of biological chemistry 1997;272(37):23334-9.
1997: A Caracciolo; I Gesualdo; Margherita Branno; Francesco Aniello; Roberto Di Lauro; Anna Palumbo
Specific cellular localization of tyrosinase mRNA during Ciona intestinalis larval development.
Development, growth & differentiation 1997;39(4):437-44.
1997: Mariastella Zannini; V Avantaggiato; E Biffali; M I Arnone; K Sato; M Pischetola; B A Taylor; S J Phillips; Antonio Simeone; Roberto Di Lauro
TTF-2, a new forkhead protein, shows a temporal expression in the developing thyroid which is consistent with a role in controlling the onset of differentiation.
The EMBO journal 1997;16(11):3185-97.
1997: Paola Lapi; Paolo Emidio Macchia; Luca Chiovato; E Biffali; Lidia Moschini; D Larizza; Mariangiola Baserga; Aldo Pinchera; Gianfranco Fenzi; Roberto Di Lauro
Mutations in the gene encoding thyroid transcription factor-1 (TTF-1) are not a frequent cause of congenital hypothyroidism (CH) with thyroid dysgenesis.
Thyroid : official journal of the American Thyroid Association 1997;7(3):383-7.
1996: L Cariello; T de Cristofaro; L Zanetti; T Cuomo; L Di Maio; G Campanella; S Rinaldi; P Zanetti; Roberto Di Lauro; Stelio Varrone
Transglutaminase activity is related to CAG repeat length in patients with Huntington's disease.
Human genetics 1996;98(6):633-5.
1996: G Esposito; Federico Fogolari; Giuseppe Damante; Silvestro Formisano; Gianluca Tell; A Leonardi; Roberto Di Lauro; Paolo Viglino
Analysis of the solution structure of the homeodomain of rat thyroid transcription factor 1 by 1H-NMR spectroscopy and restrained molecular mechanics.
European journal of biochemistry / FEBS 1996;241(1):101-13.
1996: Giuseppe Damante; Lucia Pellizzari; G Esposito; Federico Fogolari; Paolo Viglino; Dora Fabbro; Gianluca Tell; Silvestro Formisano; Roberto Di Lauro
A molecular code dictates sequence-specific DNA recognition by homeodomains.
The EMBO journal 1996;15(18):4992-5000.
1996: Lucia Pellizzari; Dora Fabbro; R Lonigro; Roberto Di Lauro; Giuseppe Damante
A network of specific minor-groove contacts is a common characteristic of paired-domain-DNA interactions.
The Biochemical journal 1996;315 ( Pt 2)():363-7.
1996: R Lonigro; M De Felice; E Biffali; Paolo Emidio Macchia; Giuseppe Damante; C Asteria; Roberto Di Lauro
Expression of thyroid transcription factor 1 gene can be regulated at the transcriptional and posttranscriptional levels.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1996;7(2):251-61.
1996: Mariastella Zannini; A Acebron; M De Felice; M I Arnone; J Martin-Pérez; Pilar Santisteban; Roberto Di Lauro
Mapping and functional role of phosphorylation sites in the thyroid transcription factor-1 (TTF-1).
The Journal of biological chemistry 1996;271(4):2249-54.
1995: M De Felice; Giuseppe Damante; Mariastella Zannini; H Francis-Lang; Roberto Di Lauro
Redundant domains contribute to the transcriptional activity of the thyroid transcription factor 1.
The Journal of biological chemistry 1995;270(44):26649-56.
1995: M I Arnone; Mariastella Zannini; Roberto Di Lauro
The DNA binding activity and the dimerization ability of the thyroid transcription factor I are redox regulated.
The Journal of biological chemistry 1995;270(20):12048-55.
1995: Anna Di Gregorio; A Spagnuolo; Filomena Ristoratore; M Pischetola; Francesco Aniello; Margherita Branno; L Cariello; Roberto Di Lauro
Cloning of ascidian homeobox genes provides evidence for a primordial chordate cluster.
Gene 1995;156(2):253-7.
1995: Roberto Di Lauro; Giuseppe Damante; M De Felice; M I Arnone; K Sato; R Lonigro; Mariastella Zannini
Molecular events in the differentiation of the thyroid gland.
Journal of endocrinological investigation 1995;18(2):117-9.
1994: Giuseppe Damante; Gianluca Tell; A Leonardi; Federico Fogolari; N Bortolotti; Roberto Di Lauro; Silvestro Formisano
Analysis of the conformation and stability of rat TTF-1 homeodomain by circular dichroism.
FEBS letters 1994;354(3):293-6.
1994: Dora Fabbro; Carla Di Loreto; C A Beltrami; A Belfiore; Roberto Di Lauro; Giuseppe Damante
Expression of thyroid-specific transcription factors TTF-1 and PAX-8 in human thyroid neoplasms.
Cancer research 1994;54(17):4744-9.
1994: Giuseppe Damante; Dora Fabbro; Lucia Pellizzari; D Civitareale; S Guazzi; M Polycarpou-Schwartz; Sabina Cauci; Franco Quadrifoglio; Silvestro Formisano; Roberto Di Lauro
Sequence-specific DNA recognition by the thyroid transcription factor-1 homeodomain.
Nucleic acids research 1994;22(15):3075-83.
1994: Giuseppe Damante; Roberto Di Lauro
Thyroid-specific gene expression.
Biochimica et biophysica acta 1994;1218(3):255-66.
1994: S Guazzi; R Lonigro; L Pintonello; Edoardo Boncinelli; Roberto Di Lauro; F Mavilio
The thyroid transcription factor-1 gene is a candidate target for regulation by Hox proteins.
The EMBO journal 1994;13(14):3339-47.
1993: Paolo Viglino; Federico Fogolari; Silvestro Formisano; N Bortolotti; Giuseppe Damante; Roberto Di Lauro; G Esposito
Structural study of rat thyroid transcription factor 1 homeodomain (TTF-1 HD) by nuclear magnetic resonance.
FEBS letters 1993;336(3):397-402.
1993: Giuseppe Damante; Gianluca Tell; Silvestro Formisano; Dora Fabbro; Lucia Pellizzari; Roberto Di Lauro
Effect of salt concentration on TTF-1 HD binding to specific and non-specific DNA sequences.
Biochemical and biophysical research communications 1993;197(2):632-8.
1992: H Francis-Lang; Mariastella Zannini; M De Felice; Maria Teresa Berlingieri; A Fusco; Roberto Di Lauro
Multiple mechanisms of interference between transformation and differentiation in thyroid cells.
Molecular and cellular biology 1992;12(12):5793-800.
1992: Mariastella Zannini; H Francis-Lang; D Plachov; Roberto Di Lauro
Pax-8, a paired domain-containing protein, binds to a sequence overlapping the recognition site of a homeodomain and activates transcription from two thyroid-specific promoters.
Molecular and cellular biology 1992;12(9):4230-41.
1992: Pilar Santisteban; A Acebrón; Maria Polycarpou-Schwarz; Roberto Di Lauro
Insulin and insulin-like growth factor I regulate a thyroid-specific nuclear protein that binds to the thyroglobulin promoter.
Molecular endocrinology (Baltimore, Md.) 1992;6(8):1310-7.
1992: H Francis-Lang; M Price; Maria Polycarpou-Schwarz; Roberto Di Lauro
Cell-type-specific expression of the rat thyroperoxidase promoter indicates common mechanisms for thyroid-specific gene expression.
Molecular and cellular biology 1992;12(2):576-88.
1992: M Price; Lazzaro Domenico; T Pohl; M G Mattei; U Rüther; JC Olivo; Denis Duboule; Roberto Di Lauro
Regional expression of the homeobox gene Nkx-2.2 in the developing mammalian forebrain.
Neuron 1992;8(2):241-55.
1991: Lazzaro Domenico; M Price; M de Felice; Roberto Di Lauro
The transcription factor TTF-1 is expressed at the onset of thyroid and lung morphogenesis and in restricted regions of the foetal brain.
Development (Cambridge, England) 1991;113(4):1093-104.
1991: M Price; M Lemaistre; M Pischetola; Roberto Di Lauro; Denis Duboule
A mouse gene related to Distal-less shows a restricted expression in the developing forebrain.
Nature 1991;351(6329):748-51.
1991: Giuseppe Damante; Roberto Di Lauro
Several regions of Antennapedia and thyroid transcription factor 1 homeodomains contribute to DNA binding specificity.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(12):5388-92.
1990: S Guazzi; M Price; M De Felice; Giuseppe Damante; M G Mattei; Roberto Di Lauro
Thyroid nuclear factor 1 (TTF-1) contains a homeodomain and displays a novel DNA binding specificity.
The EMBO journal 1990;9(11):3631-9.
1990: A J Sinclair; R Lonigro; D Civitareale; L Ghibelli; Roberto Di Lauro
The tissue-specific expression of the thyroglobulin gene requires interaction between thyroid-specific and ubiquitous factors.
European journal of biochemistry / FEBS 1990;193(2):311-8.
1989: D Civitareale; R Lonigro; A J Sinclair; Roberto Di Lauro
A thyroid-specific nuclear protein essential for tissue-specific expression of the thyroglobulin promoter.
The EMBO journal 1989;8(9):2537-42.
1989: Maria Teresa Berlingieri; A M Musti; Vittorio E Avvedimento; Roberto Di Lauro; P P Di Fiore; A Fusco
The block of thyroglobulin synthesis, which occurs upon transformation of rat thyroid epithelial cells, is at the transcriptional level and it is associated with methylation of the 5' flanking region of the gene.
Experimental cell research 1989;183(2):277-83.
1989: A J Sinclair; R Lonigro; D Civitareale; Roberto Di Lauro
Thyroid specific gene expression.
Advances in experimental medicine and biology 1989;261():373-89.
1988: Vittorio E Avvedimento; A Musti; A Fusco; M J Bonapace; Roberto Di Lauro
Neoplastic transformation inactivates specific trans-acting factor(s) required for the expression of the thyroglobulin gene.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(6):1744-8.
1987: A M Musti; V M Ursini; enrico vittorio avvedimento; V Zimarino; Roberto Di Lauro
A cell type specific factor recognizes the rat thyroglobulin promoter.
Nucleic acids research 1987;15(20):8149-66.
1987: D Civitareale; L Ghibelli; Roberto Di Lauro
Partial purification of a thyroid specific nuclear protein recognizing the thyroglobulin promoter.
Hormone and metabolic research. Supplement series 1987;17():73-7.
1986: A M Musti; enrico vittorio avvedimento; C Polistina; V M Ursini; S Obici; Lucio Nitsch; Sergio Cocozza; Roberto Di Lauro
The complete structure of the rat thyroglobulin gene.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(2):323-7.
1985: Silvestro Formisano; C Moscatelli; Raffaele Zarrilli; B Di Ieso; Renato Acquaviva; S Obici; G Palumbo; Roberto Di Lauro
Prediction of the secondary structure of the carboxy-terminal third of rat thyroglobulin.
Biochemical and biophysical research communications 1985;133(2):766-72.
1985: A Fusco; Giuseppe Portella; P P Di Fiore; Maria Teresa Berlingieri; Roberto Di Lauro; A B Schneider; Giancarlo Vecchio
A mos oncogene-containing retrovirus, myeloproliferative sarcoma virus, transforms rat thyroid epithelial cells and irreversibly blocks their differentiation pattern.
Journal of virology 1985;56(1):284-92.
1985: Vittorio E Avvedimento; Antonella Monticelli; Donatella Tramontano; C Polistina; Lucio Nitsch; Roberto Di Lauro
Differential expression of thyroglobulin gene in normal and transformed thyroid cells.
European journal of biochemistry / FEBS 1985;149(3):467-72.
1985: Roberto Di Lauro; S Obici; D Condliffe; V M Ursini; A Musti; C Moscatelli; Vittorio E Avvedimento
The sequence of 967 amino acids at the carboxyl-end of rat thyroglobulin. Location and surroundings of two thyroxine-forming sites.
European journal of biochemistry / FEBS 1985;148(1):7-11.
1985: Vittorio E Avvedimento; Roberto Di Lauro; Antonella Monticelli; F Bernardi; P Patracchini; E Calzolari; G Martini; Stelio Varrone
Mapping of human thyroglobulin gene on the long arm of chromosome 8 by in situ hybridization.
Human genetics 1985;71(2):163-6.
1984: Vittorio Tassi; Roberto Di Lauro; P Van Jaarsveld; C G Alvino
Two abnormal thyroglobulin-like polypeptides are produced from Afrikander cattle congenital goiter mRNA.
The Journal of biological chemistry 1984;259(16):10507-10.
1984: Vittorio E Avvedimento; Donatella Tramontano; M V Ursini; Antonella Monticelli; Roberto Di Lauro
The level of thyroglobulin mRNA is regulated by TSH both in vitro and in vivo.
Biochemical and biophysical research communications 1984;122(1):472-7.
1984: Vittorio E Avvedimento; A M Musti; S Obici; Sergio Cocozza; Roberto Di Lauro
Structural organization of the 3' half of the rat thyroglobulin gene.
Nucleic acids research 1984;12(8):3461-72.
1982: Roberto Di Lauro; S Obici; Angela Maria Acquaviva; C G Alvino
Construction of recombinant plasmids containing rat thyroglobulin mRNA sequences.
Gene 1982;19(1):117-25.
1982: C G Alvino; Vittorio Tassi; C Polistina; Roberto Di Lauro; S Bonatti
The segregation into microsomal vesicles and core-glycosylation in vitro of a 300-kDa rat thyroglobulin subunit.
European journal of biochemistry / FEBS 1982;125(1):15-9.
1982: C G Alvino; Vittorio Tassi; B M Paterson; Roberto Di Lauro
In vitro synthesis of 300 00 Mr rat thyroglobulin subunit.
FEBS letters 1982;137(2):307-13.