Vincenzo Di Marzo

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TOP 3
Morera Enrico; De Petrocellis Luciano; Morera Ludovica; Moriello Aniello Schiano; Ligresti Alessia; Nalli Marianna; Woodward David F; Di Marzo Vincenzo; Ortar Giorgio
Synthesis and biological evaluation of piperazinyl carbamates and ureas as fatty acid amide hydrolase (FAAH) and transient receptor potential (TRP) channel dual ligands.
Di Marzo Vincenzo; Després Jean-Pierre
CB1 antagonists for obesity--what lessons have we learned from rimonabant?
Di Marzo Vincenzo; Verrijken An; Hakkarainen Antti; Petrosino Stefania; Mertens Ilse; Lundbom Nina; Piscitelli Fabiana; Westerbacka Jukka; Soro-Paavonen Aino; Matias Isabel; Van Gaal Luc; Taskinen Marja-Riitta
Role of insulin as a negative regulator of plasma endocannabinoid levels in obese and nonobese subjects.

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All Publications

2009: Morera Enrico; De Petrocellis Luciano; Morera Ludovica; Moriello Aniello Schiano; Ligresti Alessia; Nalli Marianna; Woodward David F; Di Marzo Vincenzo; Ortar Giorgio
Synthesis and biological evaluation of piperazinyl carbamates and ureas as fatty acid amide hydrolase (FAAH) and transient receptor potential (TRP) channel dual ligands.
Bioorganic & medicinal chemistry letters 2009;19(23):6806-9.
2009: Di Marzo Vincenzo; Després Jean-Pierre
CB1 antagonists for obesity--what lessons have we learned from rimonabant?
Nature reviews. Endocrinology 2009;5(11):633-8.
2009: Di Marzo Vincenzo; Verrijken An; Hakkarainen Antti; Petrosino Stefania; Mertens Ilse; Lundbom Nina; Piscitelli Fabiana; Westerbacka Jukka; Soro-Paavonen Aino; Matias Isabel; Van Gaal Luc; Taskinen Marja-Riitta
Role of insulin as a negative regulator of plasma endocannabinoid levels in obese and nonobese subjects.
European journal of endocrinology / European Federation of Endocrine Societies 2009;161(5):715-22.
2009: Borrelli Francesca; Aviello Gabriella; Romano Barbara; Orlando Pierangelo; Capasso Raffaele; Maiello Francesco; Guadagno Federico; Petrosino Stefania; Capasso Francesco; Di Marzo Vincenzo; Izzo Angelo A
Cannabidiol, a safe and non-psychotropic ingredient of the marijuana plant Cannabis sativa, is protective in a murine model of colitis.
Journal of molecular medicine (Berlin, Germany) 2009;87(11):1111-21.
2009: Izzo Angelo A; Borrelli Francesca; Capasso Raffaele; Di Marzo Vincenzo; Mechoulam Raphael
Non-psychotropic plant cannabinoids: new therapeutic opportunities from an ancient herb.
Trends in pharmacological sciences 2009;30(10):515-27.
2009: Micale Vincenzo; Cristino Luigia; Tamburella Alessandra; Petrosino Stefania; Leggio Gian Marco; Drago Filippo; Di Marzo Vincenzo
Altered responses of dopamine D3 receptor null mice to excitotoxic or anxiogenic stimuli: Possible involvement of the endocannabinoid and endovanilloid systems.
Neurobiology of disease 2009;36(1):70-80.
2009: Pasquini Serena; Mugnaini Claudia; Brizzi Antonella; Ligresti Alessia; Di Marzo Vincenzo; Ghiron Chiara; Corelli Federico
Rapid combinatorial access to a library of 1,5-disubstituted-3-indole-N-alkylacetamides as CB2 receptor ligands.
Journal of combinatorial chemistry 2009;11(5):795-8.
2009: Izzo Angelo A; Piscitelli Fabiana; Capasso Raffaele; Aviello Gabriella; Romano Barbara; Borrelli Francesca; Petrosino Stefania; Di Marzo Vincenzo
Peripheral endocannabinoid dysregulation in obesity: relation to intestinal motility and energy processing induced by food deprivation and re-feeding.
British journal of pharmacology 2009;158(2):451-61.
2009: Di Marzo Vincenzo
The endocannabinoid system: its general strategy of action, tools for its pharmacological manipulation and potential therapeutic exploitation.
Pharmacological research : the official journal of the Italian Pharmacological Society 2009;60(2):77-84.
2009: Batetta Barbara; Griinari Mikko; Carta Gianfranca; Murru Elisabetta; Ligresti Alessia; Cordeddu Lina; Giordano Elena; Sanna Francesca; Bisogno Tiziana; Uda Sabrina; Collu Maria; Bruheim Inge; Di Marzo Vincenzo; Banni Sebastiano
Endocannabinoids may mediate the ability of (n-3) fatty acids to reduce ectopic fat and inflammatory mediators in obese Zucker rats.
The Journal of nutrition 2009;139(8):1495-501.
2009: Marini Pietro; Moriello Aniello Schiano; Cristino Luigia; Palmery Maura; De Petrocellis Luciano; Di Marzo Vincenzo
Cannabinoid CB1 receptor elevation of intracellular calcium in neuroblastoma SH-SY5Y cells: interactions with muscarinic and delta-opioid receptors.
Biochimica et biophysica acta 2009;1793(7):1289-303.
2009: Di Marzo V; Ligresti A; Cristino L
The endocannabinoid system as a link between homoeostatic and hedonic pathways involved in energy balance regulation.
International journal of obesity (2005) 2009;33 Suppl 2():S18-24.
2009: Ligresti Alessia; Petrosino Stefania; Di Marzo Vincenzo
From endocannabinoid profiling to 'endocannabinoid therapeutics'.
Current opinion in chemical biology 2009;13(3):321-31.
2009: Petrosino Stefania; Ligresti Alessia; Di Marzo Vincenzo
Endocannabinoid chemical biology: a tool for the development of novel therapies.
Current opinion in chemical biology 2009;13(3):309-20.
2009: Manera Clementina; Saccomanni Giuseppe; Adinolfi Barbara; Benetti Veronica; Ligresti Alessia; Cascio Maria Grazia; Tuccinardi Tiziano; Lucchesi Valentina; Martinelli Adriano; Nieri Paola; Masini Emanuela; Di Marzo Vincenzo; Ferrarini Pier Luigi
Rational design, synthesis, and pharmacological properties of new 1,8-naphthyridin-2(1H)-on-3-carboxamide derivatives as highly selective cannabinoid-2 receptor agonists.
Journal of medicinal chemistry 2009;52(12):3644-51.
2009: Maione Sabatino; Cristino Luigia; Migliozzi Anna Lucia; Georgiou Anne L; Starowicz Katarzyna; Salt Thomas E; Di Marzo Vincenzo
TRPV1 channels control synaptic plasticity in the developing superior colliculus.
The Journal of physiology 2009;587(Pt 11):2521-35.
2009: De Petrocellis Luciano; Di Marzo Vincenzo
Role of endocannabinoids and endovanilloids in Ca2+ signalling.
Cell calcium 2009;45(6):611-24.
2009: Bisogno Tiziana; Burston James J; Rai Ravi; Allarà Marco; Saha Bijali; Mahadevan Anu; Razdan Raj K; Wiley Jenny L; Di Marzo Vincenzo
Synthesis and pharmacological activity of a potent inhibitor of the biosynthesis of the endocannabinoid 2-arachidonoylglycerol.
ChemMedChem 2009;4(6):946-50.
2009: Appendino Giovanni; Ligresti Alessia; Minassi Alberto; Cascio Maria Grazia; Allarà Marco; Taglialatela-Scafati Orazio; Pertwee Roger G; De Petrocellis Luciano; Di Marzo Vincenzo
Conformationally constrained fatty acid ethanolamides as cannabinoid and vanilloid receptor probes.
Journal of medicinal chemistry 2009;52(9):3001-9.
2009: Maione Sabatino; Starowicz Katarzyna; Cristino Luigia; Guida Francesca; Palazzo Enza; Luongo Livio; Rossi Francesca; Marabese Ida; de Novellis Vito; Di Marzo Vincenzo
Functional interaction between TRPV1 and micro-opioid receptors in the descending antinociceptive pathway activates glutamate transmission and induces analgesia.
Journal of neurophysiology 2009;101(5):2411-22.
2009: Brizzi Antonella; Brizzi Vittorio; Cascio Maria Grazia; Corelli Federico; Guida Francesca; Ligresti Alessia; Maione Sabatino; Martinelli Adriano; Pasquini Serena; Tuccinardi Tiziano; Di Marzo Vincenzo
New resorcinol-anandamide "hybrids" as potent cannabinoid receptor ligands endowed with antinociceptive activity in vivo.
Journal of medicinal chemistry 2009;52(8):2506-14.
2009: Cottone Erika; Guastalla Alda; Pomatto Valentina; Campantico Ezio; Di Marzo Vincenzo; Franzoni Mariafosca
Goldfish CB1 mRNA expression is affected by fasting and anandamide administration.
Neuroreport 2009;20(6):595-9.
2009: De Petrocellis L; Deva R; Mainieri F; Schaefer M; Bisogno T; Ciccoli R; Ligresti A; Hill K; Nigam S; Appendino G; Di Marzo V
Chemical synthesis, pharmacological characterization, and possible formation in unicellular fungi of 3-hydroxy-anandamide.
Journal of lipid research 2009;50(4):658-66.
2009: Rossi F; Siniscalco D; Luongo L; De Petrocellis L; Bellini G; Petrosino S; Torella M; Santoro C; Nobili B; Perrotta S; Di Marzo V; Maione S
The endovanilloid/endocannabinoid system in human osteoclasts: possible involvement in bone formation and resorption.
Bone 2009;44(3):476-84.
2009: De Petrocellis Luciano; Di Marzo Vincenzo
An introduction to the endocannabinoid system: from the early to the latest concepts.
Best practice & research. Clinical endocrinology & metabolism 2009;23(1):1-15.
2009: Di Marzo Vincenzo
The endocannabinoid system in metabolic control: a preface.
Best practice & research. Clinical endocrinology & metabolism 2009;23(1):vii-ix.
2009: Di Marzo V; Côté M; Matias I; Lemieux I; Arsenault B J; Cartier A; Piscitelli F; Petrosino S; Alméras N; Després J-P
Changes in plasma endocannabinoid levels in viscerally obese men following a 1 year lifestyle modification programme and waist circumference reduction: associations with changes in metabolic risk factors.
Diabetologia 2009;52(2):213-7.
2009: Micale Vincenzo; Cristino Luigia; Tamburella Alessandra; Petrosino Stefania; Leggio Gian Marco; Drago Filippo; Di Marzo Vincenzo
Anxiolytic effects in mice of a dual blocker of fatty acid amide hydrolase and transient receptor potential vanilloid type-1 channels.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2009;34(3):593-606.
2008: Di Marzo Vincenzo; Gobbi Gabriella; Szallasi Arpad
Brain TRPV1: a depressing TR(i)P down memory lane?
Trends in pharmacological sciences 2008;29(12):594-600.
2008: Di Marzo Vincenzo
CB(1) receptor antagonism: biological basis for metabolic effects.
Drug discovery today 2008;13(23-24):1026-41.
2008: de Novellis Vito; Palazzo Enza; Rossi Francesca; De Petrocellis Luciano; Petrosino Stefania; Guida Francesca; Luongo Livio; Migliozzi Annalucia; Cristino Luigia; Marabese Ida; Starowicz Katarzyna; Di Marzo Vincenzo; Maione Sabatino;
The analgesic effect of N-arachidonoyl-serotonin, a FAAH inhibitor and TRPV1 receptor antagonist, associated with changes in rostral ventromedial medulla and locus coeruleus cell activity in rats.
Neuropharmacology 2008;55(7):1105-13.
2008: Vellani Vittorio; Petrosino Stefania; De Petrocellis Luciano; Valenti Marta; Prandini Massimiliano; Magherini Pier Cosimo; McNaughton Peter A; Di Marzo Vincenzo
Functional lipidomics. Calcium-independent activation of endocannabinoid/endovanilloid lipid signalling in sensory neurons by protein kinases C and A and thrombin.
Neuropharmacology 2008;55(8):1274-9.
2008: Ortar Giorgio; Bisogno Tiziana; Ligresti Alessia; Morera Enrico; Nalli Marianna; Di Marzo Vincenzo
Tetrahydrolipstatin analogues as modulators of endocannabinoid 2-arachidonoylglycerol metabolism.
Journal of medicinal chemistry 2008;51(21):6970-9.
2008: Maione S; Morera E; Marabese I; Ligresti A; Luongo L; Ortar G; Di Marzo V
Antinociceptive effects of tetrazole inhibitors of endocannabinoid inactivation: cannabinoid and non-cannabinoid receptor-mediated mechanisms.
British journal of pharmacology 2008;155(5):775-82.
2008: Capasso R; Borrelli F; Cascio M G; Aviello G; Huben K; Zjawiony J K; Marini P; Romano B; Di Marzo V; Capasso F; Izzo A A
Inhibitory effect of salvinorin A, from Salvia divinorum, on ileitis-induced hypermotility: cross-talk between kappa-opioid and cannabinoid CB(1) receptors.
British journal of pharmacology 2008;155(5):681-9.
2008: López-Gallardo M; Llorente R; Llorente-Berzal A; Marco E M; Prada C; Di Marzo V; Viveros M P
Neuronal and glial alterations in the cerebellar cortex of maternally deprived rats: gender differences and modulatory effects of two inhibitors of endocannabinoid inactivation.
Developmental neurobiology 2008;68(12):1429-40.
2008: Di Marzo Vincenzo
Play an ADAGIO with a STRADIVARIUS: the right patient for CB1 receptor antagonists?
Nature clinical practice. Cardiovascular medicine 2008;5(10):610-2.
2008: Llorente Ricardo; Llorente-Berzal Alvaro; Petrosino Stefania; Marco Eva-María; Guaza Carmen; Prada Carmen; López-Gallardo Meritxell; Di Marzo Vincenzo; Viveros María-Paz
Gender-dependent cellular and biochemical effects of maternal deprivation on the hippocampus of neonatal rats: a possible role for the endocannabinoid system.
Developmental neurobiology 2008;68(11):1334-47.
2008: Pasquini Serena; Botta Lorenzo; Semeraro Teresa; Mugnaini Claudia; Ligresti Alessia; Palazzo Enza; Maione Sabatino; Di Marzo Vincenzo; Corelli Federico
Investigations on the 4-quinolone-3-carboxylic acid motif. 2. Synthesis and structure-activity relationship of potent and selective cannabinoid-2 receptor agonists endowed with analgesic activity in vivo.
Journal of medicinal chemistry 2008;51(16):5075-84.
2008: Loría Frida; Petrosino Stefania; Mestre Leyre; Spagnolo Alessandra; Correa Fernando; Hernangómez Miriam; Guaza Carmen; Di Marzo Vincenzo; Docagne Fabian
Study of the regulation of the endocannabinoid system in a virus model of multiple sclerosis reveals a therapeutic effect of palmitoylethanolamide.
The European journal of neuroscience 2008;28(4):633-41.
2008: Mulder Jan; Aguado Tania; Keimpema Erik; Barabás Klaudia; Ballester Rosado Carlos J; Nguyen Laurent; Monory Krisztina; Marsicano Giovanni; Di Marzo Vincenzo; Hurd Yasmin L; Guillemot Francois; Mackie Ken; Lutz Beat; Guzmán Manuel; Lu Hui-Chen; Galve-Roperh Ismael; Harkany Tibor
Endocannabinoid signaling controls pyramidal cell specification and long-range axon patterning.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(25):8760-5.
2008: De Petrocellis Luciano; Vellani Vittorio; Schiano-Moriello Aniello; Marini Pietro; Magherini Pier Cosimo; Orlando Pierangelo; Di Marzo Vincenzo
Plant-derived cannabinoids modulate the activity of transient receptor potential channels of ankyrin type-1 and melastatin type-8.
The Journal of pharmacology and experimental therapeutics 2008;325(3):1007-15.
2008: Rubino T; Realini N; Castiglioni C; Guidali C; Viganó D; Marras E; Petrosino S; Perletti G; Maccarrone M; Di Marzo V; Parolaro D
Role in anxiety behavior of the endocannabinoid system in the prefrontal cortex.
Cerebral cortex (New York, N.Y. : 1991) 2008;18(6):1292-301.
2008: Di Marzo Vincenzo
Targeting the endocannabinoid system: to enhance or reduce?
Nature reviews. Drug discovery 2008;7(5):438-55.
2008: Ortar Giorgio; Schiano Moriello Aniello; Cascio Maria Grazia; De Petrocellis Luciano; Ligresti Alessia; Morera Enrico; Nalli Marianna; Di Marzo Vincenzo
New tetrazole-based selective anandamide uptake inhibitors.
Bioorganic & medicinal chemistry letters 2008;18(9):2820-4.
2008: Di Marzo Vincenzo; Maccarrone Mauro
FAAH and anandamide: is 2-AG really the odd one out?
Trends in pharmacological sciences 2008;29(5):229-33.
2008: Thiemann Gunnar; Di Marzo Vincenzo; Molleman Areles; Hasenöhrl Rüdiger U
The CB(1) cannabinoid receptor antagonist AM251 attenuates amphetamine-induced behavioural sensitization while causing monoamine changes in nucleus accumbens and hippocampus.
Pharmacology, biochemistry, and behavior 2008;89(3):384-91.
2008: Matias Isabel; Petrosino Stefania; Racioppi Alessandro; Capasso Raffaele; Izzo Angelo A; Di Marzo Vincenzo
Dysregulation of peripheral endocannabinoid levels in hyperglycemia and obesity: Effect of high fat diets.
Molecular and cellular endocrinology 2008;286(1-2 Suppl 1):S66-78.
2008: Aviello Gabriella; Matias Isabel; Capasso Raffaele; Petrosino Stefania; Borrelli Francesca; Orlando Pierangelo; Romano Barbara; Capasso Francesco; Di Marzo Vincenzo; Izzo Angelo A
Inhibitory effect of the anorexic compound oleoylethanolamide on gastric emptying in control and overweight mice.
Journal of molecular medicine (Berlin, Germany) 2008;86(4):413-22.
2008: Silvestri Romano; Cascio Maria Grazia; La Regina Giuseppe; Piscitelli Francesco; Lavecchia Antonio; Brizzi Antonella; Pasquini Serena; Botta Maurizio; Novellino Ettore; Di Marzo Vincenzo; Corelli Federico
Synthesis, cannabinoid receptor affinity, and molecular modeling studies of substituted 1-aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamides.
Journal of medicinal chemistry 2008;51(6):1560-76.
2008: Starowicz Katarzyna M; Cristino Luigia; Matias Isabel; Capasso Raffaele; Racioppi Alessandro; Izzo Angelo A; Di Marzo Vincenzo
Endocannabinoid dysregulation in the pancreas and adipose tissue of mice fed with a high-fat diet.
Obesity (Silver Spring, Md.) 2008;16(3):553-65.
2008: Di Marzo V; Capasso R; Matias I; Aviello G; Petrosino S; Borrelli F; Romano B; Orlando P; Capasso F; Izzo A A
The role of endocannabinoids in the regulation of gastric emptying: alterations in mice fed a high-fat diet.
British journal of pharmacology 2008;153(6):1272-80.
2008: Thiemann Gunnar; van der Stelt Mario; Petrosino Stefania; Molleman Areles; Di Marzo Vincenzo; Hasenöhrl Rüdiger U
The role of the CB1 cannabinoid receptor and its endogenous ligands, anandamide and 2-arachidonoylglycerol, in amphetamine-induced behavioural sensitization.
Behavioural brain research 2008;187(2):289-96.
2008: Cristino L; Starowicz K; De Petrocellis L; Morishita J; Ueda N; Guglielmotti V; Di Marzo V
Immunohistochemical localization of anabolic and catabolic enzymes for anandamide and other putative endovanilloids in the hippocampus and cerebellar cortex of the mouse brain.
Neuroscience 2008;151(4):955-68.
2008: Di Marzo Vincenzo; Cristino Luigia
Why endocannabinoids are not all alike.
Nature neuroscience 2008;11(2):124-6.
2008: Matias Isabel; Carta Gianfranca; Murru Elisabetta; Petrosino Stefania; Banni Sebastiano; Di Marzo Vincenzo
Effect of polyunsaturated fatty acids on endocannabinoid and N-acyl-ethanolamine levels in mouse adipocytes.
Biochimica et biophysica acta 2008;1781(1-2):52-60.
2008: Izzo Angelo A; Aviello Gabriella; Petrosino Stefania; Orlando Pierangelo; Marsicano Giovanni; Lutz Beat; Borrelli Francesca; Capasso Raffaele; Nigam Santosh; Capasso Francesco; Di Marzo Vincenzo;
Increased endocannabinoid levels reduce the development of precancerous lesions in the mouse colon.
Journal of molecular medicine (Berlin, Germany) 2008;86(1):89-98.
2008: Tam Joseph; Trembovler Victoria; Di Marzo Vincenzo; Petrosino Stefania; Leo Gabriella; Alexandrovich Alex; Regev Eran; Casap Nardy; Shteyer Arie; Ledent Catherine; Karsak Meliha; Zimmer Andreas; Mechoulam Raphael; Yirmiya Raz; Shohami Esther; Bab Itai
The cannabinoid CB1 receptor regulates bone formation by modulating adrenergic signaling.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2008;22(1):285-94.
2008: Matias Isabel; Vergoni Anna Valeria; Petrosino Stefania; Ottani Alessandra; Pocai Alessandro; Bertolini Alfio; Di Marzo Vincenzo
Regulation of hypothalamic endocannabinoid levels by neuropeptides and hormones involved in food intake and metabolism: insulin and melanocortins.
Neuropharmacology 2008;54(1):206-12.
2008: Bisogno Tiziana; Martire Alberto; Petrosino Stefania; Popoli Patrizia; Di Marzo Vincenzo
Symptom-related changes of endocannabinoid and palmitoylethanolamide levels in brain areas of R6/2 mice, a transgenic model of Huntington's disease.
Neurochemistry international 2008;52(1-2):307-13.
2008: Ortar Giorgio; Cascio Maria Grazia; Moriello Aniello Schiano; Camalli Mercedes; Morera Enrico; Nalli Marianna; Di Marzo Vincenzo
Carbamoyl tetrazoles as inhibitors of endocannabinoid inactivation: a critical revisitation.
European journal of medicinal chemistry 2008;43(1):62-72.
2008: Bisogno Tiziana; Di Marzo Vincenzo
The role of the endocannabinoid system in Alzheimer's disease: facts and hypotheses.
Current pharmaceutical design 2008;14(23):2299-3305.
2008: Di Marzo V
Endocannabinoids: synthesis and degradation.
Reviews of physiology, biochemistry and pharmacology 2008;160():1-24.
2008: Starowicz Katarzyna; Cristino Luigia; Di Marzo Vincenzo
TRPV1 receptors in the central nervous system: potential for previously unforeseen therapeutic applications.
Current pharmaceutical design 2008;14(1):42-54.
2008: Di Marzo Vincenzo; Starowicz Katarzyna
New Potential Therapies from Vanilloid Transient Receptor Cation (TRPV) Channels.
Current pharmaceutical design 2008;14(1):1.
2007: Starowicz Katarzyna; Maione Sabatino; Cristino Luigia; Palazzo Enza; Marabese Ida; Rossi Francesca; de Novellis Vito; Di Marzo Vincenzo
Tonic endovanilloid facilitation of glutamate release in brainstem descending antinociceptive pathways.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007;27(50):13739-49.
2007: Ortar Giorgio; Cascio Maria Grazia; De Petrocellis Luciano; Morera Enrico; Rossi Francesca; Schiano-Moriello Aniello; Nalli Marianna; de Novellis Vito; Woodward David F; Maione Sabatino; Di Marzo Vincenzo
New N-arachidonoylserotonin analogues with potential "dual" mechanism of action against pain.
Journal of medicinal chemistry 2007;50(26):6554-69.
2007: Della Monica Carmela; De Petrocellis Luciano; Di Marzo Vincenzo; Landi Raffaella; Izzo Irene; Spinella Aldo
Enantioselective synthesis and vanilloid activity evaluation of 1-beta-(p-methoxycinnamoyl)polygodial, an antinociceptive compound from Drymis winteri barks.
Bioorganic & medicinal chemistry letters 2007;17(23):6444-7.
2007: Manera Clementina; Cascio Maria Grazia; Benetti Veronica; Allarà Marco; Tuccinardi Tiziano; Martinelli Adriano; Saccomanni Giuseppe; Vivoli Elisa; Ghelardini Carla; Di Marzo Vincenzo; Ferrarini Pier Luigi
New 1,8-naphthyridine and quinoline derivatives as CB2 selective agonists.
Bioorganic & medicinal chemistry letters 2007;17(23):6505-10.
2007: Iuvone Teresa; Esposito Giuseppe; De Filippis Daniele; Bisogno Tiziana; Petrosino Stefania; Scuderi Caterina; Di Marzo Vincenzo; Steardo Luca;
Cannabinoid CB1 receptor stimulation affords neuroprotection in MPTP-induced neurotoxicity by attenuating S100B up-regulation in vitro.
Journal of molecular medicine (Berlin, Germany) 2007;85(12):1379-92.
2007: Bisogno Tiziana; Di Marzo Vincenzo
Short- and long-term plasticity of the endocannabinoid system in neuropsychiatric and neurological disorders.
Pharmacological research : the official journal of the Italian Pharmacological Society 2007;56(5):428-42.
2007: Matias I; Gonthier M-P; Petrosino S; Docimo L; Capasso R; Hoareau L; Monteleone P; Roche R; Izzo A A; Di Marzo V
Role and regulation of acylethanolamides in energy balance: focus on adipocytes and beta-cells.
British journal of pharmacology 2007;152(5):676-90.
2007: Minutolo F; Cascio M G; Carboni I; Bisogno T; Prota G; Bertini S; Digiacomo M; Bifulco M; Di Marzo V; Macchia M
Metabolically labile cannabinoid esters: a 'soft drug' approach for the development of cannabinoid-based therapeutic drugs.
Bioorganic & medicinal chemistry letters 2007;17(17):4878-81.
2007: Esposito Giuseppe; Iuvone Teresa; Savani Claudia; Scuderi Caterina; De Filippis Daniele; Papa Michele; Di Marzo Vincenzo; Steardo Luca
Opposing control of cannabinoid receptor stimulation on amyloid-beta-induced reactive gliosis: in vitro and in vivo evidence.
The Journal of pharmacology and experimental therapeutics 2007;322(3):1144-52.
2007: De Petrocellis Luciano; Marini Pietro; Matias Isabel; Moriello Aniello Schiano; Starowicz Katarzyna; Cristino Luigia; Nigam Santosh; Di Marzo Vincenzo
Mechanisms for the coupling of cannabinoid receptors to intracellular calcium mobilization in rat insulinoma beta-cells.
Experimental cell research 2007;313(14):2993-3004.
2007: Brizzi Antonella; Cascio Maria Grazia; Brizzi Vittorio; Bisogno Tiziana; Dinatolo Maria Teresa; Martinelli Adriano; Tuccinardi Tiziano; Di Marzo Vincenzo
Design, synthesis, binding, and molecular modeling studies of new potent ligands of cannabinoid receptors.
Bioorganic & medicinal chemistry 2007;15(16):5406-16.
2007: Soria-Gómez E; Matias I; Rueda-Orozco P E; Cisneros M; Petrosino S; Navarro L; Di Marzo V; Prospéro-García O
Pharmacological enhancement of the endocannabinoid system in the nucleus accumbens shell stimulates food intake and increases c-Fos expression in the hypothalamus.
British journal of pharmacology 2007;151(7):1109-16.
2007: Prusakiewicz Jeffery J; Turman Melissa V; Vila Andrew; Ball Heather L; Al-Mestarihi Ahmad H; Di Marzo Vincenzo; Marnett Lawrence J
Oxidative metabolism of lipoamino acids and vanilloids by lipoxygenases and cyclooxygenases.
Archives of biochemistry and biophysics 2007;464(2):260-8.
2007: Di Marzo Vincenzo; Bisogno Tiziana; De Petrocellis Luciano
Endocannabinoids and related compounds: walking back and forth between plant natural products and animal physiology.
Chemistry & biology 2007;14(7):741-56.
2007: Marabese Ida; Rossi Francesca; Palazzo Enza; de Novellis Vito; Starowicz Katarzyna; Cristino Luigia; Vita Daniela; Gatta Luisa; Guida Francesca; Di Marzo Vincenzo; Rossi Francesco; Maione Sabatino
Periaqueductal gray metabotropic glutamate receptor subtype 7 and 8 mediate opposite effects on amino acid release, rostral ventromedial medulla cell activities, and thermal nociception.
Journal of neurophysiology 2007;98(1):43-53.
2007: Karsak Meliha; Gaffal Evelyn; Date Rahul; Wang-Eckhardt Lihua; Rehnelt Jennifer; Petrosino Stefania; Starowicz Katarzyna; Steuder Regina; Schlicker Eberhard; Cravatt Benjamin; Mechoulam Raphael; Buettner Reinhard; Werner Sabine; Di Marzo Vincenzo; Tüting Thomas; Zimmer Andreas
Attenuation of allergic contact dermatitis through the endocannabinoid system.
Science (New York, N.Y.) 2007;316(5830):1494-7.
2007: Sharkey K A; Cristino L; Oland L D; Van Sickle M D; Starowicz K; Pittman Q J; Guglielmotti V; Davison J S; Di Marzo V
Arvanil, anandamide and N-arachidonoyl-dopamine (NADA) inhibit emesis through cannabinoid CB1 and vanilloid TRPV1 receptors in the ferret.
The European journal of neuroscience 2007;25(9):2773-82.
2007: De Petrocellis Luciano; Starowicz Katarzyna; Moriello Aniello Schiano; Vivese Marta; Orlando Pierangelo; Di Marzo Vincenzo
Regulation of transient receptor potential channels of melastatin type 8 (TRPM8): effect of cAMP, cannabinoid CB(1) receptors and endovanilloids.
Experimental cell research 2007;313(9):1911-20.
2007: D'Argenio Giuseppe; Petrosino Stefania; Gianfrani Carmen; Valenti Marta; Scaglione Giuseppe; Grandone Ilenia; Nigam Santosh; Sorrentini Italo; Mazzarella Giuseppe; Di Marzo Vincenzo
Overactivity of the intestinal endocannabinoid system in celiac disease and in methotrexate-treated rats.
Journal of molecular medicine (Berlin, Germany) 2007;85(5):523-30.
2007: Gonthier Marie-Paule; Hoareau Laurence; Festy Franck; Matias Isabel; Valenti Marta; Bès-Houtmann Sandrine; Rouch Claude; Robert-Da Silva Christine; Chesne Serge; Lefebvre d'Hellencourt Christian; Césari Maya; Di Marzo Vincenzo; Roche Régis
Identification of endocannabinoids and related compounds in human fat cells.
Obesity (Silver Spring, Md.) 2007;15(4):837-45.
2007: Di Marzo Vincenzo; Petrosino Stefania
Endocannabinoids and the regulation of their levels in health and disease.
Current opinion in lipidology 2007;18(2):129-40.
2007: Starowicz Katarzyna; Nigam Santosh; Di Marzo Vincenzo
Biochemistry and pharmacology of endovanilloids.
Pharmacology & therapeutics 2007;114(1):13-33.
2007: Côté M; Matias I; Lemieux I; Petrosino S; Alméras N; Després J-P; Di Marzo V
Circulating endocannabinoid levels, abdominal adiposity and related cardiometabolic risk factors in obese men.
International journal of obesity (2005) 2007;31(4):692-9.
2007: Maione S; De Petrocellis L; de Novellis V; Moriello A Schiano; Petrosino S; Palazzo E; Rossi F Sca; Woodward D F; Di Marzo V
Analgesic actions of N-arachidonoyl-serotonin, a fatty acid amide hydrolase inhibitor with antagonistic activity at vanilloid TRPV1 receptors.
British journal of pharmacology 2007;150(6):766-81.
2007: Petrosino Stefania; Palazzo Enza; de Novellis Vito; Bisogno Tiziana; Rossi Francesco; Maione Sabatino; Di Marzo Vincenzo
Changes in spinal and supraspinal endocannabinoid levels in neuropathic rats.
Neuropharmacology 2007;52(2):415-22.
2007: Marinelli Silvia; Di Marzo Vincenzo; Florenzano Fulvio; Fezza Filomena; Viscomi Maria Teresa; van der Stelt Mario; Bernardi Giorgio; Molinari Marco; Maccarrone Mauro; Mercuri Nicola B
N-arachidonoyl-dopamine tunes synaptic transmission onto dopaminergic neurons by activating both cannabinoid and vanilloid receptors.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2007;32(2):298-308.
2007: Matias Isabel; Di Marzo Vincenzo
Endocannabinoids and the control of energy balance.
Trends in endocrinology and metabolism: TEM 2007;18(1):27-37.
2007: Appendino Giovanni; Ech-Chahad Abdellah; Minassi Alberto; Bacchiega Sara; De Petrocellis Luciano; Di Marzo Vincenzo
Structure-activity relationships of the ultrapotent vanilloid resiniferatoxin (RTX): the homovanillyl moiety.
Bioorganic & medicinal chemistry letters 2007;17(1):132-5.
2007: Appendino Giovanni; Bacchiega Sara; Minassi Alberto; Cascio Maria Grazia; De Petrocellis Luciano; Di Marzo Vincenzo
The 1,2,3-triazole ring as a peptido- and olefinomimetic element: discovery of click vanilloids and cannabinoids.
Angewandte Chemie (International ed. in English) 2007;46(48):9312-5.
2006: Matias I; Wang J W; Moriello A Schiano; Nieves A; Woodward D F; Di Marzo V
Changes in endocannabinoid and palmitoylethanolamide levels in eye tissues of patients with diabetic retinopathy and age-related macular degeneration.
Prostaglandins, leukotrienes, and essential fatty acids 2006;75(6):413-8.
2006: Szabo Bela; Urbanski Michal J; Bisogno Tiziana; Di Marzo Vincenzo; Mendiguren Aitziber; Baer Wolfram U; Freiman Ilka
Depolarization-induced retrograde synaptic inhibition in the mouse cerebellar cortex is mediated by 2-arachidonoylglycerol.
The Journal of physiology 2006;577(Pt 1):263-80.
2006: Palazzo Enza; de Novellis Vito; Petrosino Stefania; Marabese Ida; Vita Daniela; Giordano Catia; Di Marzo Vincenzo; Mangoni Giuseppe Salvatore; Rossi Francesco; Maione Sabatino
Neuropathic pain and the endocannabinoid system in the dorsal raphe: pharmacological treatment and interactions with the serotonergic system.
The European journal of neuroscience 2006;24(7):2011-20.
2006: Cascio M G; Bisogno T; Palazzo E; Thomas A; van der Stelt M; Brizzi A; de Novellis V; Marabese I; Ross R; van de Doelen T; Brizzi V; Pertwee R; Maione S; Di Marzo V
In vitro and in vivo pharmacology of synthetic olivetol- or resorcinol-derived cannabinoid receptor ligands.
British journal of pharmacology 2006;149(4):431-40.
2006: Melis Miriam; Pillolla Giuliano; Bisogno Tiziana; Minassi Alberto; Petrosino Stefania; Perra Simona; Muntoni Anna Lisa; Lutz Beat; Gessa Gian Luigi; Marsicano Giovanni; Di Marzo Vincenzo; Pistis Marco
Protective activation of the endocannabinoid system during ischemia in dopamine neurons.
Neurobiology of disease 2006;24(1):15-27.
2006: Lee Joohyung; Di Marzo Vincenzo; Brotchie Jonathan M
A role for vanilloid receptor 1 (TRPV1) and endocannabinnoid signalling in the regulation of spontaneous and L-DOPA induced locomotion in normal and reserpine-treated rats.
Neuropharmacology 2006;51(3):557-65.
2006: Ligresti Alessia; Moriello Aniello Schiano; Starowicz Katarzyna; Matias Isabel; Pisanti Simona; De Petrocellis Luciano; Laezza Chiara; Portella Giuseppe; Bifulco Maurizio; Di Marzo Vincenzo
Antitumor activity of plant cannabinoids with emphasis on the effect of cannabidiol on human breast carcinoma.
The Journal of pharmacology and experimental therapeutics 2006;318(3):1375-87.
2006: Di Marzo Maria; Casapullo Agostino; Bifulco Giuseppe; Cimino Paola; Ligresti Alessia; Di Marzo Vincenzo; Riccio Raffaele; Gomez-Paloma Luigi
Synthesis, conformational analysis and CB1 binding affinity of hairpin-like anandamide pseudopeptide mimetics.
Journal of peptide science : an official publication of the European Peptide Society 2006;12(9):575-91.
2006: Wettschureck Nina; van der Stelt Mario; Tsubokawa Hiroshi; Krestel Heinz; Moers Alexandra; Petrosino Stefania; Schütz Günther; Di Marzo Vincenzo; Offermanns Stefan
Forebrain-specific inactivation of Gq/G11 family G proteins results in age-dependent epilepsy and impaired endocannabinoid formation.
Molecular and cellular biology 2006;26(15):5888-94.
2006: Matias Isabel; Gonthier Marie-Paule; Orlando Pierangelo; Martiadis Vassilis; De Petrocellis Luciano; Cervino Cristina; Petrosino Stefania; Hoareau Laurence; Festy Franck; Pasquali Renato; Roche Regis; Maj Mario; Pagotto Uberto; Monteleone Palmiero; Di Marzo Vincenzo
Regulation, function, and dysregulation of endocannabinoids in models of adipose and beta-pancreatic cells and in obesity and hyperglycemia.
The Journal of clinical endocrinology and metabolism 2006;91(8):3171-80.
2006: Balas Laurence; Cascio Maria Grazia; Di Marzo Vincenzo; Durand Thierry
Synthesis of a potential photoactivatable anandamide analog.
Bioorganic & medicinal chemistry letters 2006;16(14):3765-8.
2006: Kamprath Kornelia; Marsicano Giovanni; Tang Jianrong; Monory Krisztina; Bisogno Tiziana; Di Marzo Vincenzo; Lutz Beat; Wotjak Carsten T
Cannabinoid CB1 receptor mediates fear extinction via habituation-like processes.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006;26(25):6677-86.
2006: van der Stelt M; Mazzola C; Esposito G; Matias I; Petrosino S; De Filippis D; Micale V; Steardo L; Drago F; Iuvone T; Di Marzo V
Endocannabinoids and beta-amyloid-induced neurotoxicity in vivo: effect of pharmacological elevation of endocannabinoid levels.
Cellular and molecular life sciences : CMLS 2006;63(12):1410-24.
2006: Bilsland Lynsey G; Dick James R T; Pryce Gareth; Petrosino Stefania; Di Marzo Vincenzo; Baker David; Greensmith Linda
Increasing cannabinoid levels by pharmacological and genetic manipulation delay disease progression in SOD1 mice.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006;20(7):1003-5.
2006: Appendino Giovanni; Minassi Alberto; Berton Luca; Moriello Aniello Schiano; Cascio Maria Grazia; De Petrocellis Luciano; Di Marzo Vincenzo
Oxyhomologues of anandamide and related endolipids: chemoselective synthesis and biological activity.
Journal of medicinal chemistry 2006;49(7):2333-8.
2006: Schiano Moriello Aniello; Balas Laurence; Ligresti Alessia; Cascio Maria Grazia; Durand Thierry; Morera Enrico; Ortar Giorgio; Di Marzo Vincenzo
Development of the first potential covalent inhibitors of anandamide cellular uptake.
Journal of medicinal chemistry 2006;49(7):2320-32.
2006: Mechoulam R; Berry E M; Avraham Y; Di Marzo V; Fride E
Endocannabinoids, feeding and suckling--from our perspective.
International journal of obesity (2005) 2006;30 Suppl 1():S24-8.
2006: Márquez Nieves; De Petrocellis Luciano; Caballero Francisco J; Macho Antonio; Schiano-Moriello Aniello; Minassi Alberto; Appendino Giovanni; Muñoz Eduardo; Di Marzo Vincenzo
Iodinated N-acylvanillamines: potential "multiple-target" anti-inflammatory agents acting via the inhibition of t-cell activation and antagonism at vanilloid TRPV1 channels.
Molecular pharmacology 2006;69(4):1373-82.
2006: Di Marzo Vincenzo
A brief history of cannabinoid and endocannabinoid pharmacology as inspired by the work of British scientists.
Trends in pharmacological sciences 2006;27(3):134-40.
2006: McPartland John M; Matias Isabel; Di Marzo Vincenzo; Glass Michelle
Evolutionary origins of the endocannabinoid system.
Gene 2006;370():64-74.
2006: D'Argenio Giuseppe; Valenti Marta; Scaglione Giuseppe; Cosenza Vittorio; Sorrentini Italo; Di Marzo Vincenzo
Up-regulation of anandamide levels as an endogenous mechanism and a pharmacological strategy to limit colon inflammation.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006;20(3):568-70.
2006: Maione Sabatino; Bisogno Tiziana; de Novellis Vito; Palazzo Enza; Cristino Luigia; Valenti Marta; Petrosino Stefania; Guglielmotti Vittorio; Rossi Francesco; Di Marzo Vincenzo
Elevation of endocannabinoid levels in the ventrolateral periaqueductal grey through inhibition of fatty acid amide hydrolase affects descending nociceptive pathways via both cannabinoid receptor type 1 and transient receptor potential vanilloid type-1 receptors.
The Journal of pharmacology and experimental therapeutics 2006;316(3):969-82.
2006: Tzavara Eleni T; Li Dominic L; Moutsimilli Larissa; Bisogno Tiziana; Di Marzo Vincenzo; Phebus Lee A; Nomikos George G; Giros Bruno
Endocannabinoids activate transient receptor potential vanilloid 1 receptors to reduce hyperdopaminergia-related hyperactivity: therapeutic implications.
Biological psychiatry 2006;59(6):508-15.
2006: Bisogno Tiziana; Cascio Maria Grazia; Saha Bijali; Mahadevan Anu; Urbani Paolo; Minassi Alberto; Appendino Giovanni; Saturnino Carmela; Martin Billy; Razdan Raj; Di Marzo Vincenzo
Development of the first potent and specific inhibitors of endocannabinoid biosynthesis.
Biochimica et biophysica acta 2006;1761(2):205-12.
2006: Grimaldi Claudia; Pisanti Simona; Laezza Chiara; Malfitano Anna Maria; Santoro Antonietta; Vitale Mario; Caruso Maria Gabriella; Notarnicola Maria; Iacuzzo Irma; Portella Giuseppe; Di Marzo Vincenzo; Bifulco Maurizio
Anandamide inhibits adhesion and migration of breast cancer cells.
Experimental cell research 2006;312(4):363-73.
2006: Malfitano Anna Maria; Matarese Giuseppe; Pisanti Simona; Grimaldi Claudia; Laezza Chiara; Bisogno Tiziana; Di Marzo Vincenzo; Lechler Robert I; Bifulco Maurizio
Arvanil inhibits T lymphocyte activation and ameliorates autoimmune encephalomyelitis.
Journal of neuroimmunology 2006;171(1-2):110-9.
2006: Appendino Giovanni; Cascio Maria Grazia; Bacchiega Sara; Moriello Aniello Schiano; Minassi Alberto; Thomas Adèle; Ross Ruth; Pertwee Roger; De Petrocellis Luciano; Di Marzo Vincenzo
First "hybrid" ligands of vanilloid TRPV1 and cannabinoid CB2 receptors and non-polyunsaturated fatty acid-derived CB2-selective ligands.
FEBS letters 2006;580(2):568-74.
2006: Ligresti Alessia; Cascio Maria Grazia; Pryce Gareth; Kulasegram Sanjitha; Beletskaya Irina; De Petrocellis Luciano; Saha Bijali; Mahadevan Anu; Visintin Cristina; Wiley Jenny L; Baker David; Martin Billy R; Razdan Raj K; Di Marzo Vincenzo
New potent and selective inhibitors of anandamide reuptake with antispastic activity in a mouse model of multiple sclerosis.
British journal of pharmacology 2006;147(1):83-91.
2006: Urbani Paolo; Cavallo Paolo; Cascio Maria Grazia; Buonerba Mariafrancesca; De Martino Giovanni; Di Marzo Vincenzo; Saturnino Carmela
New metabolically stable fatty acid amide ligands of cannabinoid receptors: Synthesis and receptor affinity studies.
Bioorganic & medicinal chemistry letters 2006;16(1):138-41.
2006: Matias I; Di Marzo V
Endocannabinoid synthesis and degradation, and their regulation in the framework of energy balance.
Journal of endocrinological investigation 2006;29(3 Suppl):15-26.
2006: Cristino L; de Petrocellis L; Pryce G; Baker D; Guglielmotti V; Di Marzo V
Immunohistochemical localization of cannabinoid type 1 and vanilloid transient receptor potential vanilloid type 1 receptors in the mouse brain.
Neuroscience 2006;139(4):1405-15.
2006: Di Marzo Vincenzo; Petrocellis Luciano De
Plant, synthetic, and endogenous cannabinoids in medicine.
Annual review of medicine 2006;57():553-74.
2005: Ligresti Alessia; Cascio Maria Grazia; Di Marzo Vincenzo
Endocannabinoid metabolic pathways and enzymes.
Current drug targets. CNS and neurological disorders 2005;4(6):615-23.
2005: Brizzi Antonella; Brizzi Vittorio; Cascio Maria Grazia; Bisogno Tiziana; Sirianni Rossella; Di Marzo Vincenzo
Design, synthesis, and binding studies of new potent ligands of cannabinoid receptors.
Journal of medicinal chemistry 2005;48(23):7343-50.
2005: Cabranes Ana; Venderova Katerina; de Lago Eva; Fezza Filomena; Sánchez Antonio; Mestre Leyre; Valenti Marta; García-Merino Antonio; Ramos José Antonio; Di Marzo Vincenzo; Fernández-Ruiz Javier
Decreased endocannabinoid levels in the brain and beneficial effects of agents activating cannabinoid and/or vanilloid receptors in a rat model of multiple sclerosis.
Neurobiology of disease 2005;20(2):207-17.
2005: Valenti M; Cottone E; Martinez R; De Pedro N; Rubio M; Viveros M P; Franzoni M F; Delgado M J; Di Marzo V
The endocannabinoid system in the brain of Carassius auratus and its possible role in the control of food intake.
Journal of neurochemistry 2005;95(3):662-72.
2005: Van Sickle Marja D; Duncan Marnie; Kingsley Philip J; Mouihate Abdeslam; Urbani Paolo; Mackie Ken; Stella Nephi; Makriyannis Alexandros; Piomelli Daniele; Davison Joseph S; Marnett Lawrence J; Di Marzo Vincenzo; Pittman Quentin J; Patel Kamala D; Sharkey Keith A
Identification and functional characterization of brainstem cannabinoid CB2 receptors.
Science (New York, N.Y.) 2005;310(5746):329-32.
2005: Sancho Rocío; de la Vega Laureano; Macho Antonio; Appendino Giovanni; Di Marzo Vincenzo; Muñoz Eduardo
Mechanisms of HIV-1 inhibition by the lipid mediator N-arachidonoyldopamine.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(6):3990-9.
2005: Capasso Raffaele; Matias Isabel; Lutz Beat; Borrelli Francesca; Capasso Francesco; Marsicano Giovanni; Mascolo Nicola; Petrosino Stefania; Monory Krisztina; Valenti Marta; Di Marzo Vincenzo; Izzo Angelo A
Fatty acid amide hydrolase controls mouse intestinal motility in vivo.
Gastroenterology 2005;129(3):941-51.
2005: van der Stelt Mario; Trevisani Marcello; Vellani Vittorio; De Petrocellis Luciano; Schiano Moriello Aniello; Campi Barbara; McNaughton Peter; Geppetti Piero; Di Marzo Vincenzo
Anandamide acts as an intracellular messenger amplifying Ca2+ influx via TRPV1 channels.
The EMBO journal 2005;24(17):3026-37.
2005: van der Stelt Mario; Di Marzo Vincenzo
Anandamide as an intracellular messenger regulating ion channel activity.
Prostaglandins & other lipid mediators 2005;77(1-4):111-22.
2005: Darmani Nissar A; McClanahan Bryan A; Trinh Chung; Petrosino Stefania; Valenti Marta; Di Marzo Vincenzo
Cisplatin increases brain 2-arachidonoylglycerol (2-AG) and concomitantly reduces intestinal 2-AG and anandamide levels in the least shrew.
Neuropharmacology 2005;49(4):502-13.
2005: de Lago Eva; Petrosino Stefania; Valenti Marta; Morera Enrico; Ortega-Gutierrez Silvia; Fernandez-Ruiz Javier; Di Marzo Vincenzo
Effect of repeated systemic administration of selective inhibitors of endocannabinoid inactivation on rat brain endocannabinoid levels.
Biochemical pharmacology 2005;70(3):446-52.
2005: Ortega-Gutiérrez Silvia; Molina-Holgado Eduardo; Arévalo-Martín Angel; Correa Fernando; Viso Alma; López-Rodríguez María L; Di Marzo Vincenzo; Guaza Carmen
Activation of the endocannabinoid system as therapeutic approach in a murine model of multiple sclerosis.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(10):1338-40.
2005: De Petrocellis Luciano; Di Marzo Vincenzo
Lipids as regulators of the activity of transient receptor potential type V1 (TRPV1) channels.
Life sciences 2005;77(14):1651-66.
2005: Appendino Giovanni; Daddario Nives; Minassi Alberto; Moriello Aniello Schiano; De Petrocellis Luciano; Di Marzo Vincenzo
The taming of capsaicin. Reversal of the vanilloid activity of N-acylvanillamines by aromatic iodination.
Journal of medicinal chemistry 2005;48(14):4663-9.
2005: de Lago Eva; Urbani Paolo; Ramos José Antonio; Di Marzo Vincenzo; Fernández-Ruiz Javier
Arvanil, a hybrid endocannabinoid and vanilloid compound, behaves as an antihyperkinetic agent in a rat model of Huntington's disease.
Brain research 2005;1050(1-2):210-6.
2005: van der Stelt Mario; Fox Susan H; Hill Michael; Crossman Alan R; Petrosino Stefania; Di Marzo Vincenzo; Brotchie Jonathan M
A role for endocannabinoids in the generation of parkinsonism and levodopa-induced dyskinesia in MPTP-lesioned non-human primate models of Parkinson's disease.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(9):1140-2.
2005: Bisogno Tiziana; Ligresti Alessia; Di Marzo Vincenzo
The endocannabinoid signalling system: biochemical aspects.
Pharmacology, biochemistry, and behavior 2005;81(2):224-38.
2005: Matias Isabel; McPartland John M; Di Marzo Vincenzo
Occurrence and possible biological role of the endocannabinoid system in the sea squirt Ciona intestinalis.
Journal of neurochemistry 2005;93(5):1141-56.
2005: Darmani Nissar A; Izzo Angelo A; Degenhardt Brian; Valenti Marta; Scaglione Giuseppe; Capasso Raffaele; Sorrentini Italo; Di Marzo Vincenzo
Involvement of the cannabimimetic compound, N-palmitoyl-ethanolamine, in inflammatory and neuropathic conditions: review of the available pre-clinical data, and first human studies.
Neuropharmacology 2005;48(8):1154-63.
2005: Monteleone Palmiero; Matias Isabelle; Martiadis Vassilis; De Petrocellis Luciano; Maj Mario; Di Marzo Vincenzo
Blood levels of the endocannabinoid anandamide are increased in anorexia nervosa and in binge-eating disorder, but not in bulimia nervosa.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2005;30(6):1216-21.
2005: Di Marzo Vincenzo; Matias Isabel
Endocannabinoid control of food intake and energy balance.
Nature neuroscience 2005;8(5):585-9.
2005: Chen June; Matias Isabel; Dinh Tim; Lu Ta; Venezia Sonia; Nieves Amelia; Woodward David F; Di Marzo Vincenzo
Finding of endocannabinoids in human eye tissues: implications for glaucoma.
Biochemical and biophysical research communications 2005;330(4):1062-7.
2005: Mestre Leyre; Correa Fernando; Arévalo-Martín Angel; Molina-Holgado Eduardo; Valenti Marta; Ortar Giorgio; Di Marzo Vincenzo; Guaza Carmen
Pharmacological modulation of the endocannabinoid system in a viral model of multiple sclerosis.
Journal of neurochemistry 2005;92(6):1327-39.
2005: Appendino Giovanni; De Petrocellis Luciano; Trevisani Marcello; Minassi Alberto; Daddario Nives; Moriello Aniello Schiano; Gazzieri David; Ligresti Alessia; Campi Barbara; Fontana Gabriele; Pinna Christian; Geppetti Pierangelo; Di Marzo Vincenzo
Development of the first ultra-potent "capsaicinoid" agonist at transient receptor potential vanilloid type 1 (TRPV1) channels and its therapeutic potential.
The Journal of pharmacology and experimental therapeutics 2005;312(2):561-70.
2005: Di Marzo V; De Petrocellis L; Bisogno T
The biosynthesis, fate and pharmacological properties of endocannabinoids.
Handbook of experimental pharmacology 2005;(168):147-85.
2005: van der Stelt Mario; Di Marzo Vincenzo
Cannabinoid receptors and their role in neuroprotection.
Neuromolecular medicine 2005;7(1-2):37-50.
2004: Holt Sandra; Rocksén David; Bucht Anders; Petersen Gitte; Hansen Harald S; Valenti Marta; Di Marzo Vincenzo; Fowler Christopher J
Lipopolysaccharide-induced pulmonary inflammation is not accompanied by a release of anandamide into the lavage fluid or a down-regulation of the activity of fatty acid amide hydrolase.
Life sciences 2004;76(4):461-72.
2004: Melis Miriam; Perra Simona; Muntoni Anna Lisa; Pillolla Giuliano; Lutz Beat; Marsicano Giovanni; Di Marzo Vincenzo; Gessa Gian Luigi; Pistis Marco
Prefrontal cortex stimulation induces 2-arachidonoyl-glycerol-mediated suppression of excitation in dopamine neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(47):10707-15.
2004: Soderstrom Ken; Tian Qiyu; Valenti Marta; Di Marzo Vincenzo
Endocannabinoids link feeding state and auditory perception-related gene expression.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(44):10013-21.
2004: Viganò Daniela; Valenti Marta; Cascio Maria Grazia; Di Marzo Vincenzo; Parolaro Daniela; Rubino Tiziana
Changes in endocannabinoid levels in a rat model of behavioural sensitization to morphine.
The European journal of neuroscience 2004;20(7):1849-57.
2004: González Sara; Valenti Marta; de Miguel Rosario; Fezza Filomena; Fernández-Ruiz Javier; Di Marzo Vincenzo; Ramos José A
Changes in endocannabinoid contents in reward-related brain regions of alcohol-exposed rats, and their possible relevance to alcohol relapse.
British journal of pharmacology 2004;143(4):455-64.
2004: Di Marzo Vincenzo; Ligresti Alessia; Morera Enrico; Nalli Marianna; Ortar Giorgio
The anandamide membrane transporter. Structure-activity relationships of anandamide and oleoylethanolamine analogs with phenyl rings in the polar head group region.
Bioorganic & medicinal chemistry 2004;12(19):5161-9.
2004: Bifulco Maurizio; Laezza Chiara; Valenti Marta; Ligresti Alessia; Portella Giuseppe; DI Marzo Vincenzo
A new strategy to block tumor growth by inhibiting endocannabinoid inactivation.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2004;18(13):1606-8.
2004: Di Marzo Vincenzo; Bifulco Maurizio; De Petrocellis Luciano
The endocannabinoid system and its therapeutic exploitation.
Nature reviews. Drug discovery 2004;3(9):771-84.
2004: De Petrocellis Luciano; Chu Constance J; Moriello Aniello Schiano; Kellner Juliane C; Walker J Michael; Di Marzo Vincenzo
Actions of two naturally occurring saturated N-acyldopamines on transient receptor potential vanilloid 1 (TRPV1) channels.
British journal of pharmacology 2004;143(2):251-6.
2004: Fowler Christopher J; Tiger Gunnar; Ligresti Alessia; López-Rodríguez María L; Di Marzo Vincenzo
Selective inhibition of anandamide cellular uptake versus enzymatic hydrolysis--a difficult issue to handle.
European journal of pharmacology 2004;492(1):1-11.
2004: Van Der Stelt Mario; Di Marzo Vincenzo
Endovanilloids. Putative endogenous ligands of transient receptor potential vanilloid 1 channels.
European journal of biochemistry / FEBS 2004;271(10):1827-34.
2004: González Sara; Fernández-Ruiz Javier; Di Marzo Vincenzo; Hernández Mariluz; Arévalo Cristina; Nicanor Cristina; Cascio Maria Grazia; Ambrosio Emilio; Ramos José A
Behavioral and molecular changes elicited by acute administration of SR141716 to Delta9-tetrahydrocannabinol-tolerant rats: an experimental model of cannabinoid abstinence.
Drug and alcohol dependence 2004;74(2):159-70.
2004: Ligresti Alessia; Morera Enrico; Van Der Stelt Mario; Monory Krisztina; Lutz Beat; Ortar Giorgio; Di Marzo Vincenzo
Further evidence for the existence of a specific process for the membrane transport of anandamide.
The Biochemical journal 2004;380(Pt 1):265-72.
2004: Matias I; Chen J; De Petrocellis L; Bisogno T; Ligresti A; Fezza F; Krauss A H-P; Shi L; Protzman C E; Li C; Liang Y; Nieves A L; Kedzie K M; Burk R M; Di Marzo V; Woodward D F
Prostaglandin ethanolamides (prostamides): in vitro pharmacology and metabolism.
The Journal of pharmacology and experimental therapeutics 2004;309(2):745-57.
2004: Valenti M; Viganò D; Casico M G; Rubino T; Steardo L; Parolaro D; Di Marzo V
Differential diurnal variations of anandamide and 2-arachidonoyl-glycerol levels in rat brain.
Cellular and molecular life sciences : CMLS 2004;61(7-8):945-50.
2004: De Petrocellis Luciano; Cascio Maria Grazia; Di Marzo Vincenzo
The endocannabinoid system: a general view and latest additions.
British journal of pharmacology 2004;141(5):765-74.
2004: de Lago Eva; Ligresti Alessia; Ortar Giorgio; Morera Enrico; Cabranes Ana; Pryce Gareth; Bifulco Maurizio; Baker David; Fernandez-Ruiz Javier; Di Marzo Vincenzo
In vivo pharmacological actions of two novel inhibitors of anandamide cellular uptake.
European journal of pharmacology 2004;484(2-3):249-57.
2004: Grazia Cascio Maria; Minassi Alberto; Ligresti Alessia; Appendino Giovanni; Burstein Sumner; Di Marzo Vincenzo
A structure-activity relationship study on N-arachidonoyl-amino acids as possible endogenous inhibitors of fatty acid amide hydrolase.
Biochemical and biophysical research communications 2004;314(1):192-6.
2003: van der Stelt Mario; Di Marzo Vincenzo
The endocannabinoid system in the basal ganglia and in the mesolimbic reward system: implications for neurological and psychiatric disorders.
European journal of pharmacology 2003;480(1-3):133-50.
2003: Bisogno Tiziana; Howell Fiona; Williams Gareth; Minassi Alberto; Cascio Maria Grazia; Ligresti Alessia; Matias Isabel; Schiano-Moriello Aniello; Paul Praveen; Williams Emma-Jane; Gangadharan Uma; Hobbs Carl; Di Marzo Vincenzo; Doherty Patrick
Cloning of the first sn1-DAG lipases points to the spatial and temporal regulation of endocannabinoid signaling in the brain.
The Journal of cell biology 2003;163(3):463-8.
2003: Sancho Rocio; de la Vega Laureano; Appendino Giovanni; Di Marzo Vincenzo; Macho Antonio; Munoz Eduardo
The CB1/VR1 agonist arvanil induces apoptosis through an FADD/caspase-8-dependent pathway.
British journal of pharmacology 2003;140(6):1035-44.
2003: Han Bingnan; McPhail Kerry L; Ligresti Alessia; Di Marzo Vincenzo; Gerwick William H
Semiplenamides A-G, fatty acid amides from a Papua New Guinea collection of the marine cyanobacterium Lyngbya semiplena.
Journal of natural products 2003;66(10):1364-8.
2003: Marsicano Giovanni; Goodenough Sharon; Monory Krisztina; Hermann Heike; Eder Matthias; Cannich Astrid; Azad Shahnaz C; Cascio Maria Grazia; Gutiérrez Silvia Ortega; van der Stelt Mario; López-Rodriguez Maria Luz; Casanova Emilio; Schütz Günther; Zieglgänsberger Walter; Di Marzo Vincenzo; Behl Christian; Lutz Beat
CB1 cannabinoid receptors and on-demand defense against excitotoxicity.
Science (New York, N.Y.) 2003;302(5642):84-8.
2003: Portella Giuseppe; Laezza Chiara; Laccetti Paolo; De Petrocellis Luciano; Di Marzo Vincenzo; Bifulco Maurizio
Inhibitory effects of cannabinoid CB1 receptor stimulation on tumor growth and metastatic spreading: actions on signals involved in angiogenesis and metastasis.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003;17(12):1771-3.
2003: Izzo Angelo A; Capasso Francesco; Costagliola Anna; Bisogno Tiziana; Marsicano Giovanni; Ligresti Alessia; Matias Isabel; Capasso Raffaele; Pinto Luisa; Borrelli Francesca; Cecio Aldo; Lutz Beat; Mascolo Nicola; Di Marzo Vincenzo
An endogenous cannabinoid tone attenuates cholera toxin-induced fluid accumulation in mice.
Gastroenterology 2003;125(3):765-74.
2003: Ligresti Alessia; Bisogno Tiziana; Matias Isabel; De Petrocellis Luciano; Cascio Maria Grazia; Cosenza Vittorio; D'argenio Giuseppe; Scaglione Giuseppe; Bifulco Maurizio; Sorrentini Italo; Di Marzo Vincenzo
Possible endocannabinoid control of colorectal cancer growth.
Gastroenterology 2003;125(3):677-87.
2003: De Marchi Nicola; De Petrocellis Luciano; Orlando Pierangelo; Daniele Fabiana; Fezza Filomena; Di Marzo Vincenzo
Endocannabinoid signalling in the blood of patients with schizophrenia.
Lipids in health and disease 2003;2():5.
2003: Harrison Selena; De Petrocellis Luciano; Trevisani Marcello; Benvenuti Francesca; Bifulco Maurizio; Geppetti Pierangelo; Di Marzo Vincenzo
Capsaicin-like effects of N-arachidonoyl-dopamine in the isolated guinea pig bronchi and urinary bladder.
European journal of pharmacology 2003;475(1-3):107-14.
2003: Appendino Giovanni; Harrison Selena; De Petrocellis Luciano; Daddario Nives; Bianchi Federica; Schiano Moriello Aniello; Trevisani Marcello; Benvenuti Francesca; Geppetti Pierangelo; Di Marzo Vincenzo
Halogenation of a capsaicin analogue leads to novel vanilloid TRPV1 receptor antagonists.
British journal of pharmacology 2003;139(8):1417-24.
2003: Fezza Filomena; Dillwith Jack W; Bisogno Tiziana; Tucker James S; Di Marzo Vincenzo; Sauer John R
Endocannabinoids and related fatty acid amides, and their regulation, in the salivary glands of the lone star tick.
Biochimica et biophysica acta 2003;1633(1):61-7.
2003: Di Marzo Vincenzo
Manipulation of the endocannabinoid system by a general anaesthetic.
British journal of pharmacology 2003;139(5):885-6.
2003: Viganò Daniela; Grazia Cascio Maria; Rubino Tiziana; Fezza Filomena; Vaccani Angelo; Di Marzo Vincenzo; Parolaro Daniela
Chronic morphine modulates the contents of the endocannabinoid, 2-arachidonoyl glycerol, in rat brain.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2003;28(6):1160-7.
2003: Veldhuis W B; van der Stelt M; Wadman M W; van Zadelhoff G; Maccarrone M; Fezza F; Veldink G A; Vliegenthart J F G; Bär P R; Nicolay K; Di Marzo V
Neuroprotection by the endogenous cannabinoid anandamide and arvanil against in vivo excitotoxicity in the rat: role of vanilloid receptors and lipoxygenases.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003;23(10):4127-33.
2003: Ortar Giorgio; Ligresti Alessia; De Petrocellis Luciano; Morera Enrico; Di Marzo Vincenzo
Novel selective and metabolically stable inhibitors of anandamide cellular uptake.
Biochemical pharmacology 2003;65(9):1473-81.
2003: Bifulco Maurizio; Di Marzo Vincenzo
[The endocannabinoid system as a target for the development of new drugs for cancer therapy]
Recenti progressi in medicina 2003;94(5):194-8.
2003: Marinelli Silvia; Di Marzo Vincenzo; Berretta Nicola; Matias Isabel; Maccarrone Mauro; Bernardi Giorgio; Mercuri Nicola B
Presynaptic facilitation of glutamatergic synapses to dopaminergic neurons of the rat substantia nigra by endogenous stimulation of vanilloid receptors.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003;23(8):3136-44.
2003: Chu Constance J; Huang Susan M; De Petrocellis Luciano; Bisogno Tiziana; Ewing Scott A; Miller Jeffrey D; Zipkin Robert E; Daddario Nives; Appendino Giovanni; Di Marzo Vincenzo; Walker J Michael
N-oleoyldopamine, a novel endogenous capsaicin-like lipid that produces hyperalgesia.
The Journal of biological chemistry 2003;278(16):13633-9.
2003: Hermann H; De Petrocellis L; Bisogno T; Schiano Moriello A; Lutz B; Di Marzo V
Dual effect of cannabinoid CB1 receptor stimulation on a vanilloid VR1 receptor-mediated response.
Cellular and molecular life sciences : CMLS 2003;60(3):607-16.
2003: Lastres-Becker Isabel; de Miguel Rosario; De Petrocellis Luciano; Makriyannis Alexandros; Di Marzo Vincenzo; Fernández-Ruiz Javier
Compounds acting at the endocannabinoid and/or endovanilloid systems reduce hyperkinesia in a rat model of Huntington's disease.
Journal of neurochemistry 2003;84(5):1097-109.
2003: Matias I; Léonhardt M; Lesage J; De Petrocellis L; Dupouy J P; Vieau D; Di Marzo V
Effect of maternal under-nutrition on pup body weight and hypothalamic endocannabinoid levels.
Cellular and molecular life sciences : CMLS 2003;60(2):382-9.
2003: Sancho Rocío; Calzado Marco A; Di Marzo Vincenzo; Appendino Giovanni; Muñoz Eduardo
Anandamide inhibits nuclear factor-kappaB activation through a cannabinoid receptor-independent pathway.
Molecular pharmacology 2003;63(2):429-38.
2003: Appendino Giovanni; Ligresti Alessia; Minassi Alberto; Daddario Nives; Bisogno Tiziana; Di Marzo Vincenzo
Homologues and isomers of noladin ether, a putative novel endocannabinoid: interaction with rat cannabinoid CB(1) receptors.
Bioorganic & medicinal chemistry letters 2003;13(1):43-6.
2003: De Petrocellis Luciano; Bisogno Tiziana; Di Marzo Vincenzo
Neuromodulatory actions neuromodulatory actions of endocannabinoids in pain and sedation.
Advances in experimental medicine and biology 2003;523():215-25.
2002: Mascolo Nicola; Izzo Angelo A; Ligresti Alessia; Costagliola Anna; Pinto Luisa; Cascio Maria G; Maffia Pasquale; Cecio Aldo; Capasso Francesco; Di Marzo Vincenzo
The endocannabinoid system and the molecular basis of paralytic ileus in mice.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002;16(14):1973-5.
2002: Esposito Giuseppe; Ligresti Alessia; Izzo Angelo A; Bisogno Tiziana; Ruvo Menotti; Di Rosa Massimo; Di Marzo Vincenzo; Iuvone Teresa
The endocannabinoid system protects rat glioma cells against HIV-1 Tat protein-induced cytotoxicity. Mechanism and regulation.
The Journal of biological chemistry 2002;277(52):50348-54.
2002: González Sara; Cascio Maria Grazia; Fernández-Ruiz Javier; Fezza Filomena; Di Marzo Vincenzo; Ramos José A
Changes in endocannabinoid contents in the brain of rats chronically exposed to nicotine, ethanol or cocaine.
Brain research 2002;954(1):73-81.
2002: van der Stelt Mario; Veldhuis Wouter B; Maccarrone Mauro; Bär Peter R; Nicolay Klaas; Veldink Gerrit A; Di Marzo Vincenzo; Vliegenthart Johannes F G
Acute neuronal injury, excitotoxicity, and the endocannabinoid system.
Molecular neurobiology 2002;26(2-3):317-46.
2002: De Petrocellis Luciano; Bisogno Tiziana; Ligresti Alessia; Bifulco Maurizio; Melck Dominique; Di Marzo Vincenzo
Effect on cancer cell proliferation of palmitoylethanolamide, a fatty acid amide interacting with both the cannabinoid and vanilloid signalling systems.
Fundamental & clinical pharmacology 2002;16(4):297-302.
2002: Appendino Giovanni; Minassi Alberto; Morello Aniello Schiano; De Petrocellis Luciano; Di Marzo Vincenzo
N-Acylvanillamides: development of an expeditious synthesis and discovery of new acyl templates for powerful activation of the vanilloid receptor.
Journal of medicinal chemistry 2002;45(17):3739-45.
2002: Matias Isabel; Pochard Pierre; Orlando Pierangelo; Salzet Michel; Pestel Joel; Di Marzo Vincenzo
Presence and regulation of the endocannabinoid system in human dendritic cells.
European journal of biochemistry / FEBS 2002;269(15):3771-8.
2002: Marsicano Giovanni; Wotjak Carsten T; Azad Shahnaz C; Bisogno Tiziana; Rammes Gerhard; Cascio Maria Grazia; Hermann Heike; Tang Jianrong; Hofmann Clementine; Zieglgänsberger Walter; Di Marzo Vincenzo; Lutz Beat
The endogenous cannabinoid system controls extinction of aversive memories.
Nature 2002;418(6897):530-4.
2002: Di Marzo Vincenzo; Blumberg Peter M; Szallasi Arpad
Endovanilloid signaling in pain.
Current opinion in neurobiology 2002;12(4):372-9.
2002: Pinto Luisa; Izzo Angelo A; Cascio Maria Grazia; Bisogno Tiziana; Hospodar-Scott Karen; Brown David R; Mascolo Nicola; Di Marzo Vincenzo; Capasso Francesco
Endocannabinoids as physiological regulators of colonic propulsion in mice.
Gastroenterology 2002;123(1):227-34.
2002: Huang Susan M; Bisogno Tiziana; Trevisani Marcello; Al-Hayani Abdulmonem; De Petrocellis Luciano; Fezza Filomena; Tognetto Michele; Petros Timothy J; Krey Jocelyn F; Chu Constance J; Miller Jeffrey D; Davies Stephen N; Geppetti Pierangelo; Walker J Michael; Di Marzo Vincenzo
An endogenous capsaicin-like substance with high potency at recombinant and native vanilloid VR1 receptors.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(12):8400-5.
2002: Kirkham Tim C; Williams Claire M; Fezza Filomena; Di Marzo Vincenzo
Endocannabinoid levels in rat limbic forebrain and hypothalamus in relation to fasting, feeding and satiation: stimulation of eating by 2-arachidonoyl glycerol.
British journal of pharmacology 2002;136(4):550-7.
2002: Bifulco Maurizio; Di Marzo Vincenzo
Targeting the endocannabinoid system in cancer therapy: a call for further research.
Nature medicine 2002;8(6):547-50.
2002: Brooks Jason W; Pryce Gareth; Bisogno Tiziana; Jaggar Siân I; Hankey Deborah J R; Brown Peter; Bridges Daniel; Ledent Catherine; Bifulco Maurizio; Rice Andrew S C; Di Marzo Vincenzo; Baker David
Arvanil-induced inhibition of spasticity and persistent pain: evidence for therapeutic sites of action different from the vanilloid VR1 receptor and cannabinoid CB(1)/CB(2) receptors.
European journal of pharmacology 2002;439(1-3):83-92.
2002: Di Marzo Vincenzo; Griffin Graeme; De Petrocellis Luciano; Brandi Ines; Bisogno Tiziana; Williams William; Grier Mark C; Kulasegram Sanjitha; Mahadevan Anu; Razdan Raj K; Martin Billy R
A structure/activity relationship study on arvanil, an endocannabinoid and vanilloid hybrid.
The Journal of pharmacology and experimental therapeutics 2002;300(3):984-91.
2002: Di Marzo Vincenzo; De Petrocellis L; Fezza F; Ligresti A; Bisogno T
Anandamide receptors.
Prostaglandins, leukotrienes, and essential fatty acids 2002;66(2-3):377-91.
2002: Di Marzo Vincenzo
Endocannabinoids in the new millennium.
Prostaglandins, leukotrienes, and essential fatty acids 2002;66(2-3):91-2.
2002: Fezza Filomena; Bisogno Tiziana; Minassi Alberto; Appendino Giovanni; Mechoulam Raphael; Di Marzo Vincenzo
Noladin ether, a putative novel endocannabinoid: inactivation mechanisms and a sensitive method for its quantification in rat tissues.
FEBS letters 2002;513(2-3):294-8.
2002: Wenger Tibor; Gerendai Ida; Fezza Filomena; González Sara; Bisogno Tiziana; Fernandez-Ruiz Javier; Di Marzo Vincenzo
The hypothalamic levels of the endocannabinoid, anandamide, peak immediately before the onset of puberty in female rats.
Life sciences 2002;70(12):1407-14.
2002: Maccarrone Mauro; Bisogno Tiziana; Valensise Herbert; Lazzarin Natalia; Fezza Filomena; Manna Claudio; Di Marzo Vincenzo; Finazzi-Agrò Alessandro
Low fatty acid amide hydrolase and high anandamide levels are associated with failure to achieve an ongoing pregnancy after IVF and embryo transfer.
Molecular human reproduction 2002;8(2):188-95.
2002: Melck Dominique; Bisogno Tiziana; De Petrocellis Luciano; Beaulieu Pierre; Rice Andrew S C; Di Marzo Vincenzo
Cannabimimetic eicosanoids in cancer and inflammation: an update.
Advances in experimental medicine and biology 2002;507():381-6.
2002: Bisogno Tiziana; De Petrocellis Luciano; Di Marzo Vincenzo
Fatty acid amide hydrolase, an enzyme with many bioactive substrates. Possible therapeutic implications.
Current pharmaceutical design 2002;8(7):533-47.
2001: Bifulco M; Laezza C; Portella G; Vitale M; Orlando P; De Petrocellis L; Di Marzo V
Control by the endogenous cannabinoid system of ras oncogene-dependent tumor growth.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(14):2745-7.
2001: van der Stelt M; Veldhuis W B; van Haaften G W; Fezza F; Bisogno T; Bar P R; Veldink G A; Vliegenthart J F; Di Marzo V; Nicolay K
Exogenous anandamide protects rat brain against acute neuronal injury in vivo.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2001;21(22):8765-71.
2001: Huang S M; Bisogno T; Petros T J; Chang S Y; Zavitsanos P A; Zipkin R E; Sivakumar R; Coop A; Maeda D Y; De Petrocellis L; Burstein S; Di Marzo V; Walker J M
Identification of a new class of molecules, the arachidonyl amino acids, and characterization of one member that inhibits pain.
The Journal of biological chemistry 2001;276(46):42639-44.
2001: Bisogno T; Hanus L; De Petrocellis L; Tchilibon S; Ponde D E; Brandi I; Moriello A S; Davis J B; Mechoulam R; Di Marzo V
Molecular targets for cannabidiol and its synthetic analogues: effect on vanilloid VR1 receptors and on the cellular uptake and enzymatic hydrolysis of anandamide.
British journal of pharmacology 2001;134(4):845-52.
2001: De Petrocellis L; Davis J B; Di Marzo V
Palmitoylethanolamide enhances anandamide stimulation of human vanilloid VR1 receptors.
FEBS letters 2001;506(3):253-6.
2001: Izzo A A; Fezza F; Capasso R; Bisogno T; Pinto L; Iuvone T; Esposito G; Mascolo N; Di Marzo V; Capasso F
Cannabinoid CB1-receptor mediated regulation of gastrointestinal motility in mice in a model of intestinal inflammation.
British journal of pharmacology 2001;134(3):563-70.
2001: Maccarrone M; De Petrocellis L; Bari M; Fezza F; Salvati S; Di Marzo V; Finazzi-Agrò A
Lipopolysaccharide downregulates fatty acid amide hydrolase expression and increases anandamide levels in human peripheral lymphocytes.
Archives of biochemistry and biophysics 2001;393(2):321-8.
2001: Di Marzo V; Melck D; Orlando P; Bisogno T; Zagoory O; Bifulco M; Vogel Z; De Petrocellis L
Palmitoylethanolamide inhibits the expression of fatty acid amide hydrolase and enhances the anti-proliferative effect of anandamide in human breast cancer cells.
The Biochemical journal 2001;358(Pt 1):249-55.
2001: McPartland J; Di Marzo V; De Petrocellis L; Mercer A; Glass M
Cannabinoid receptors are absent in insects.
The Journal of comparative neurology 2001;436(4):423-9.
2001: Lastres-Becker I; Fezza F; Cebeira M; Bisogno T; Ramos J A; Milone A; Fernández-Ruiz J; Di Marzo V
Changes in endocannabinoid transmission in the basal ganglia in a rat model of Huntington's disease.
Neuroreport 2001;12(10):2125-9.
2001: Di Marzo V; Bisogno T; De Petrocellis L
Anandamide: some like it hot.
Trends in pharmacological sciences 2001;22(7):346-9.
2001: Breivogel C S; Griffin G; Di Marzo V; Martin B R
Evidence for a new G protein-coupled cannabinoid receptor in mouse brain.
Molecular pharmacology 2001;60(1):155-63.
2001: De Petrocellis L; Harrison S; Bisogno T; Tognetto M; Brandi I; Smith G D; Creminon C; Davis J B; Geppetti P; Di Marzo V
The vanilloid receptor (VR1)-mediated effects of anandamide are potently enhanced by the cAMP-dependent protein kinase.
Journal of neurochemistry 2001;77(6):1660-3.
2001: Pagotto U; Marsicano G; Fezza F; Theodoropoulou M; Grübler Y; Stalla J; Arzberger T; Milone A; Losa M; Di Marzo V; Lutz B; Stalla G K
Normal human pituitary gland and pituitary adenomas express cannabinoid receptor type 1 and synthesize endogenous cannabinoids: first evidence for a direct role of cannabinoids on hormone modulation at the human pituitary level.
The Journal of clinical endocrinology and metabolism 2001;86(6):2687-96.
2001: Fride E; Ginzburg Y; Breuer A; Bisogno T; Di Marzo V; Mechoulam R
Critical role of the endogenous cannabinoid system in mouse pup suckling and growth.
European journal of pharmacology 2001;419(2-3):207-14.
2001: Di Marzo V; Lastres-Becker I; Bisogno T; De Petrocellis L; Milone A; Davis J B; Fernandez-Ruiz J J
Hypolocomotor effects in rats of capsaicin and two long chain capsaicin homologues.
European journal of pharmacology 2001;420(2-3):123-31.
2001: Berger A; Crozier G; Bisogno T; Cavaliere P; Innis S; Di Marzo V
Anandamide and diet: inclusion of dietary arachidonate and docosahexaenoate leads to increased brain levels of the corresponding N-acylethanolamines in piglets.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(11):6402-6.
2001: Di Marzo V; Goparaju S K; Wang L; Liu J; Bátkai S; Járai Z; Fezza F; Miura G I; Palmiter R D; Sugiura T; Kunos G
Leptin-regulated endocannabinoids are involved in maintaining food intake.
Nature 2001;410(6830):822-5.
2001: De Petrocellis L; Bisogno T; Maccarrone M; Davis J B; Finazzi-Agro A; Di Marzo V
The activity of anandamide at vanilloid VR1 receptors requires facilitated transport across the cell membrane and is limited by intracellular metabolism.
The Journal of biological chemistry 2001;276(16):12856-63.
2001: Bisogno T; MacCarrone M; De Petrocellis L; Jarrahian A; Finazzi-Agrò A; Hillard C; Di Marzo V
The uptake by cells of 2-arachidonoylglycerol, an endogenous agonist of cannabinoid receptors.
European journal of biochemistry / FEBS 2001;268(7):1982-9.
2001: Bezuglov V; Bobrov M; Gretskaya N; Gonchar A; Zinchenko G; Melck D; Bisogno T; Di Marzo V; Kuklev D; Rossi J C; Vidal J P; Durand T
Synthesis and biological evaluation of novel amides of polyunsaturated fatty acids with dopamine.
Bioorganic & medicinal chemistry letters 2001;11(4):447-9.
2001: Di Marzo V; Bisogno T; De Petrocellis L; Brandi I; Jefferson R G; Winckler R L; Davis J B; Dasse O; Mahadevan A; Razdan R K; Martin B R
Highly selective CB(1) cannabinoid receptor ligands and novel CB(1)/VR(1) vanilloid receptor "hybrid" ligands.
Biochemical and biophysical research communications 2001;281(2):444-51.
2001: Baker D; Pryce G; Croxford J L; Brown P; Pertwee R G; Makriyannis A; Khanolkar A; Layward L; Fezza F; Bisogno T; Di Marzo V
Endocannabinoids control spasticity in a multiple sclerosis model.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(2):300-2.
2000: Di Marzo V; Breivogel C S; Tao Q; Bridgen D T; Razdan R K; Zimmer A M; Zimmer A; Martin B R
Levels, metabolism, and pharmacological activity of anandamide in CB(1) cannabinoid receptor knockout mice: evidence for non-CB(1), non-CB(2) receptor-mediated actions of anandamide in mouse brain.
Journal of neurochemistry 2000;75(6):2434-44.
2000: Bisogno T; Melck D; Bobrov MYu; Gretskaya N M; Bezuglov V V; De Petrocellis L; Di Marzo V
N-acyl-dopamines: novel synthetic CB(1) cannabinoid-receptor ligands and inhibitors of anandamide inactivation with cannabimimetic activity in vitro and in vivo.
The Biochemical journal 2000;351 Pt 3():817-24.
2000: Di Marzo V; Breivogel C; Bisogno T; Melck D; Patrick G; Tao Q; Szallasi A; Razdan R K; Martin B R
Neurobehavioral activity in mice of N-vanillyl-arachidonyl-amide.
European journal of pharmacology 2000;406(3):363-74.
2000: De Petrocellis L; Bisogno T; Davis J B; Pertwee R G; Di Marzo V
Overlap between the ligand recognition properties of the anandamide transporter and the VR1 vanilloid receptor: inhibitors of anandamide uptake with negligible capsaicin-like activity.
FEBS letters 2000;483(1):52-6.
2000: Martin B R; Beletskaya I; Patrick G; Jefferson R; Winckler R; Deutsch D G; Di Marzo V; Dasse O; Mahadevan A; Razdan R K
Cannabinoid properties of methylfluorophosphonate analogs.
The Journal of pharmacology and experimental therapeutics 2000;294(3):1209-18.
2000: Di Marzo V; Bifulco M; De Petrocellis L
Endocannabinoids and multiple sclerosis: a blessing from the 'inner bliss'?
Trends in pharmacological sciences 2000;21(6):195-7.
2000: Beaulieu1 P; Bisogno1 T; Punwar S; Farquhar-Smith W P; Ambrosino G; Di Marzo V; Rice A S
Role of the endogenous cannabinoid system in the formalin test of persistent pain in the rat.
European journal of pharmacology 2000;396(2-3):85-92.
2000: Maccarrone M; Bari M; Lorenzon T; Bisogno T; Di Marzo V; Finazzi-Agrò A
Anandamide uptake by human endothelial cells and its regulation by nitric oxide.
The Journal of biological chemistry 2000;275(18):13484-92.
2000: Di Marzo V; Melck D; De Petrocellis L; Bisogno T
Cannabimimetic fatty acid derivatives in cancer and inflammation.
Prostaglandins & other lipid mediators 2000;61(1-2):43-61.
2000: Di Marzo V; Berrendero F; Bisogno T; González S; Cavaliere P; Romero J; Cebeira M; Ramos J A; Fernández-Ruiz J J
Enhancement of anandamide formation in the limbic forebrain and reduction of endocannabinoid contents in the striatum of delta9-tetrahydrocannabinol-tolerant rats.
Journal of neurochemistry 2000;74(4):1627-35.
2000: González S; Bisogno T; Wenger T; Manzanares J; Milone A; Berrendero F; Di Marzo V; Ramos J A; Fernández-Ruiz J J
Sex steroid influence on cannabinoid CB(1) receptor mRNA and endocannabinoid levels in the anterior pituitary gland.
Biochemical and biophysical research communications 2000;270(1):260-6.
2000: Melck D; De Petrocellis L; Orlando P; Bisogno T; Laezza C; Bifulco M; Di Marzo V
Suppression of nerve growth factor Trk receptors and prolactin receptors by endocannabinoids leads to inhibition of human breast and prostate cancer cell proliferation.
Endocrinology 2000;141(1):118-26.
1999: Melck D; Rueda D; Galve-Roperh I; De Petrocellis L; Guzmán M; Di Marzo V
Involvement of the cAMP/protein kinase A pathway and of mitogen-activated protein kinase in the anti-proliferative effects of anandamide in human breast cancer cells.
FEBS letters 1999;463(3):235-40.
1999: Bisogno T; Delton-Vandenbroucke I; Milone A; Lagarde M; Di Marzo V
Biosynthesis and inactivation of N-arachidonoylethanolamine (anandamide) and N-docosahexaenoylethanolamine in bovine retina.
Archives of biochemistry and biophysics 1999;370(2):300-7.
1999: Berrendero F; Sepe N; Ramos J A; Di Marzo V; Fernández-Ruiz J J
Analysis of cannabinoid receptor binding and mRNA expression and endogenous cannabinoid contents in the developing rat brain during late gestation and early postnatal period.
Synapse (New York, N.Y.) 1999;33(3):181-91.
1999: Di Marzo V; Bisogno T; De Petrocellis L; Melck D; Martin B R
Cannabimimetic fatty acid derivatives: the anandamide family and other endocannabinoids.
Current medicinal chemistry 1999;6(8):721-44.
1999: González S; Manzanares J; Berrendero F; Wenger T; Corchero J; Bisogno T; Romero J; Fuentes J A; Di Marzo V; Ramos J A; Fernández-Ruiz J
Identification of endocannabinoids and cannabinoid CB(1) receptor mRNA in the pituitary gland.
Neuroendocrinology 1999;70(2):137-45.
1999: Melck D; Bisogno T; De Petrocellis L; Chuang H; Julius D; Bifulco M; Di Marzo V
Unsaturated long-chain N-acyl-vanillyl-amides (N-AVAMs): vanilloid receptor ligands that inhibit anandamide-facilitated transport and bind to CB1 cannabinoid receptors.
Biochemical and biophysical research communications 1999;262(1):275-84.
1999: Di Marzo V; Bisogno T; De Petrocellis L; Melck D; Orlando P; Wagner J A; Kunos G
Biosynthesis and inactivation of the endocannabinoid 2-arachidonoylglycerol in circulating and tumoral macrophages.
European journal of biochemistry / FEBS 1999;264(1):258-67.
1999: Zygmunt P M; Petersson J; Andersson D A; Chuang H; Sørgård M; Di Marzo V; Julius D; Högestätt E D
Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamide.
Nature 1999;400(6743):452-7.
1999: Bisogno T; Melck D; De Petrocellis L; Di Marzo V
Phosphatidic acid as the biosynthetic precursor of the endocannabinoid 2-arachidonoylglycerol in intact mouse neuroblastoma cells stimulated with ionomycin.
Journal of neurochemistry 1999;72(5):2113-9.
1999: Bisogno T; Berrendero F; Ambrosino G; Cebeira M; Ramos J A; Fernandez-Ruiz J J; Di Marzo V
Brain regional distribution of endocannabinoids: implications for their biosynthesis and biological function.
Biochemical and biophysical research communications 1999;256(2):377-80.
1999: Ueda N; Katayama K; Kurahashi Y; Suzuki M; Suzuki H; Yamamoto S; Katoh I; Di Marzo V; De Petrocellis L
Enzymological and molecular biological studies on anandamide amidohydrolase.
Advances in experimental medicine and biology 1999;469():513-8.
1999: Di Marzo V
Biosynthesis and inactivation of endocannabinoids: relevance to their proposed role as neuromodulators.
Life sciences 1999;65(6-7):645-55.
1999: Di Marzo V; De Petrocellis L; Bisogno T; Melck D
Metabolism of anandamide and 2-arachidonoylglycerol: an historical overview and some recent developments.
Lipids 1999;34 Suppl():S319-25.
1999: De Petrocellis L; Melck D; Bisogno T; Milone A; Di Marzo V
Finding of the endocannabinoid signalling system in Hydra, a very primitive organism: possible role in the feeding response.
Neuroscience 1999;92(1):377-87.
1998: Di Marzo V; Deutsch D G
Biochemistry of the endogenous ligands of cannabinoid receptors.
Neurobiology of disease 1998;5(6 Pt B):386-404.
1998: Di Marzo V; Melck D; Bisogno T; De Petrocellis L
Endocannabinoids: endogenous cannabinoid receptor ligands with neuromodulatory action.
Trends in neurosciences 1998;21(12):521-8.
1998: Di Marzo V; Sepe N; De Petrocellis L; Berger A; Crozier G; Fride E; Mechoulam R
Trick or treat from food endocannabinoids?
Nature 1998;396(6712):636-7.
1998: Mechoulam R; Fride E; Di Marzo V
Endocannabinoids.
European journal of pharmacology 1998;359(1):1-18.
1998: Di Marzo V; Bisogno T; Melck D; Ross R; Brockie H; Stevenson L; Pertwee R; De Petrocellis L
Interactions between synthetic vanilloids and the endogenous cannabinoid system.
FEBS letters 1998;436(3):449-54.
1998: Ben-Shabat S; Fride E; Sheskin T; Tamiri T; Rhee M H; Vogel Z; Bisogno T; De Petrocellis L; Di Marzo V; Mechoulam R
An entourage effect: inactive endogenous fatty acid glycerol esters enhance 2-arachidonoyl-glycerol cannabinoid activity.
European journal of pharmacology 1998;353(1):23-31.
1998: Bisogno T; Melck D; De Petrocellis L; Bobrov MYu; Gretskaya N M; Bezuglov V V; Sitachitta N; Gerwick W H; Di Marzo V
Arachidonoylserotonin and other novel inhibitors of fatty acid amide hydrolase.
Biochemical and biophysical research communications 1998;248(3):515-22.
1998: Bisogno T; Katayama K; Melck D; Ueda N; De Petrocellis L; Yamamoto S; Di Marzo V
Biosynthesis and degradation of bioactive fatty acid amides in human breast cancer and rat pheochromocytoma cells--implications for cell proliferation and differentiation.
European journal of biochemistry / FEBS 1998;254(3):634-42.
1998: Di Marzo V
'Endocannabinoids' and other fatty acid derivatives with cannabimimetic properties: biochemistry and possible physiopathological relevance.
Biochimica et biophysica acta 1998;1392(2-3):153-75.
1998: Di Marzo V; Bisogno T; Sugiura T; Melck D; De Petrocellis L
The novel endogenous cannabinoid 2-arachidonoylglycerol is inactivated by neuronal- and basophil-like cells: connections with anandamide.
The Biochemical journal 1998;331 ( Pt 1)():15-9.
1998: Sepe N; De Petrocellis L; Montanaro F; Cimino G; Di Marzo V
Bioactive long chain N-acylethanolamines in five species of edible bivalve molluscs. Possible implications for mollusc physiology and sea food industry.
Biochimica et biophysica acta 1998;1389(2):101-11.
1997: Bisogno T; Sepe N; De Petrocellis L; Mechoulam R; Di Marzo V
The sleep inducing factor oleamide is produced by mouse neuroblastoma cells.
Biochemical and biophysical research communications 1997;239(2):473-9.
1997: Mechoulam R; Fride E; Hanus L; Sheskin T; Bisogno T; Di Marzo V; Bayewitch M; Vogel Z
Anandamide may mediate sleep induction.
Nature 1997;389(6646):25-6.
1997: Bisogno T; Ventriglia M; Milone A; Mosca M; Cimino G; Di Marzo V
Occurrence and metabolism of anandamide and related acyl-ethanolamides in ovaries of the sea urchin Paracentrotus lividus.
Biochimica et biophysica acta 1997;1345(3):338-48.
1997: Bisogno T; Sepe N; Melck D; Maurelli S; De Petrocellis L; Di Marzo V
Biosynthesis, release and degradation of the novel endogenous cannabimimetic metabolite 2-arachidonoylglycerol in mouse neuroblastoma cells.
The Biochemical journal 1997;322 ( Pt 2)():671-7.
1997: De Petrocellis L; Melck D; Ueda N; Maurelli S; Kurahashi Y; Yamamoto S; Marino G; Di Marzo V
Novel inhibitors of brain, neuronal, and basophilic anandamide amidohydrolase.
Biochemical and biophysical research communications 1997;231(1):82-8.
1997: Bisogno T; Maurelli S; Melck D; De Petrocellis L; Di Marzo V
Biosynthesis, uptake, and degradation of anandamide and palmitoylethanolamide in leukocytes.
The Journal of biological chemistry 1997;272(6):3315-23.
1997: De Petrocellis L; Melck D; Ueda N; Kurahashi Y; Bisogno T; Yamamoto S; Di Marzo V
Brain and peripheral anandamide amidohydrolase and its inhibition by synthetic arachidonate analogues.
Advances in experimental medicine and biology 1997;433():259-63.
1997: Bisogno T; Sepe N; De Petrocellis L; Di Marzo V
Biosynthesis of 2-arachidonoyl-glycerol, a novel cannabimimetic eicosanoid, in mouse neuroblastoma cells.
Advances in experimental medicine and biology 1997;433():201-4.
1997: Di Marzo V; De Petrocellis L; Bisogno T; Maurelli S
The endogenous cannabimimetic eicosanoid, anandamide, induces arachidonate release in J774 mouse macrophages.
Advances in experimental medicine and biology 1997;407():341-6.
1996: Di Marzo V; De Petrocellis L; Sugiura T; Waku K
Potential biosynthetic connections between the two cannabimimetic eicosanoids, anandamide and 2-arachidonoyl-glycerol, in mouse neuroblastoma cells.
Biochemical and biophysical research communications 1996;227(1):281-8.
1996: De Petrocellis L; Orlando P; Gavagnin M; Ventriglia M; Cimino G; Di Marzo V
Novel diterpenoid diacylglycerols from marine molluscs: potent morphogens and protein kinase C activators.
Experientia 1996;52(9):874-7.
1996: Di Marzo V; De Petrocellis L; Sepe N; Buono A
Biosynthesis of anandamide and related acylethanolamides in mouse J774 macrophages and N18 neuroblastoma cells.
The Biochemical journal 1996;316 ( Pt 3)():977-84.
1995: Maurelli S; Bisogno T; De Petrocellis L; Di Luccia A; Marino G; Di Marzo V
Two novel classes of neuroactive fatty acid amides are substrates for mouse neuroblastoma 'anandamide amidohydrolase'.
FEBS letters 1995;377(1):82-6.
1995: Fontana A; Di Marzo V; Cadas H; Piomelli D
Analysis of anandamide, an endogenous cannabinoid substance, and of other natural N-acylethanolamines.
Prostaglandins, leukotrienes, and essential fatty acids 1995;53(4):301-8.
1995: Di Marzo V
Arachidonic acid and eicosanoids as targets and effectors in second messenger interactions.
Prostaglandins, leukotrienes, and essential fatty acids 1995;53(4):239-54.
1995: De Petrocellis L; Orlando P; Di Marzo V
Anandamide, an endogenous cannabinomimetic substance, modulates rat brain protein kinase C in vitro.
Biochemistry and molecular biology international 1995;36(6):1127-33.
1995: Di Marzo V; Fontana A
Anandamide, an endogenous cannabinomimetic eicosanoid: 'killing two birds with one stone'.
Prostaglandins, leukotrienes, and essential fatty acids 1995;53(1):1-11.
1994: Di Marzo V; Fontana A; Cadas H; Schinelli S; Cimino G; Schwartz J C; Piomelli D
Formation and inactivation of endogenous cannabinoid anandamide in central neurons.
Nature 1994;372(6507):686-91.
1994: Di Marzo V; Gianfrani C; De Petrocellis L; Milone A; Cimino G
Polyunsaturated-fatty-acid oxidation in Hydra: regioselectivity, substrate-dependent enantioselectivity and possible biological role.
The Biochemical journal 1994;300 ( Pt 2)():501-7.
1993: Di Marzo V; De Petrocellis L; Gianfrani C; Cimino G
Biosynthesis, structure and biological activity of hydroxyeicosatetraenoic acids in Hydra vulgaris.
The Biochemical journal 1993;295 ( Pt 1)():23-9.
1992: Di Marzo V; Piomelli D
Participation of prostaglandin E2 in dopamine D2 receptor-dependent potentiation of arachidonic acid release.
Journal of neurochemistry 1992;59(1):379-82.
1991: Di Marzo V; Cimino G; Crispino A; Minardi C; Sodano G; Spinella A
A novel multifunctional metabolic pathway in a marine mollusc leads to unprecedented prostaglandin derivatives (prostaglandin 1,15-lactones).
The Biochemical journal 1991;273 ( Pt 3)():593-600.
1991: Cimino G; Crispino A; Di Marzo V; Sodano G; Spinella A; Villani G
A marine mollusc provides the first example of in vivo storage of prostaglandins: prostaglandin-1,15-lactones.
Experientia 1991;47(1):56-60.
1991: Di Marzo V; Cimino G; Sodano G; Spinella A; Villani G
A novel prostaglandin metabolic pathway from a marine mollusc: prostaglandin-1,15-lactones.
Advances in prostaglandin, thromboxane, and leukotriene research 1991;21A():129-32.
1991: De Petrocellis L; Di Marzo V; Arcà B; Gavagnin M; Minei R; Cimino G
The effect of diterpenoidic diacylglycerols on tentacle regeneration in Hydra vulgaris.
Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology 1991;100(3):603-7.
1990: Cimino G; Crispino A; Di Marzo V; Gavagnin M; Ros J D
Oxytoxins, bioactive molecules produced by the marine opisthobranch mollusc Oxynoe olivacea from a diet-derived precursor.
Experientia 1990;46(7):767-70.

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