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Rosa Di Paola

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TOP 3
Antonella Marucci; Maria Monti; Piero Pucci; Vincenzo Trischitta; Flora Cozzolino; Claudia Dimatteo; Rosa Di Paola
Role of GALNT2 in the modulation of ENPP1 expression, and insulin signaling and action: GALNT2: A novel modulator of insulin signaling.
Claudia Dimatteo; René Massimiliano Marsano; Antonella Marucci; Antonio Palazzo; Vincenzo Trischitta; Carmela Cisternino; Rosa Di Paola
Role of somatomedin-B-like domains on ENPP1 inhibition of insulin signaling.
Simonetta Bacci; Roberto Baratta; Agostino Consoli; Massimiliano Copetti; Rosa Di Paola; Natalia Di Pietro; Sara Di Silvestre; Alessandro Doria; Massimo Federici; Lucia Frittitta; Renato Lauro; Lorenzo Malatino; Francesca Mallamaci; Luana Mercuri; Eleonora Morini; Assunta Pandolfi; Fabio Pellegrini; Sabrina Prudente; Stefano Rizza; Belinda Spoto; Alessandra Testa; Giovanni Tripepi; Yuan-Yuan Zhang; Carmine Zoccali; Vincenzo Trischitta
Joint effect of insulin signaling genes on cardiovascular events and on whole body and endothelial insulin resistance.

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All Publications

2013: Antonella Marucci; Maria Monti; Piero Pucci; Vincenzo Trischitta; Flora Cozzolino; Claudia Dimatteo; Rosa Di Paola
Role of GALNT2 in the modulation of ENPP1 expression, and insulin signaling and action: GALNT2: A novel modulator of insulin signaling.
Biochimica et biophysica acta 2013;1833(6):1388-95.
2013: Claudia Dimatteo; René Massimiliano Marsano; Antonella Marucci; Antonio Palazzo; Vincenzo Trischitta; Carmela Cisternino; Rosa Di Paola
Role of somatomedin-B-like domains on ENPP1 inhibition of insulin signaling.
Biochimica et biophysica acta 2013;1833(3):552-8.
2013: Simonetta Bacci; Roberto Baratta; Agostino Consoli; Massimiliano Copetti; Rosa Di Paola; Natalia Di Pietro; Sara Di Silvestre; Alessandro Doria; Massimo Federici; Lucia Frittitta; Renato Lauro; Lorenzo Malatino; Francesca Mallamaci; Luana Mercuri; Eleonora Morini; Assunta Pandolfi; Fabio Pellegrini; Sabrina Prudente; Stefano Rizza; Belinda Spoto; Alessandra Testa; Giovanni Tripepi; Yuan-Yuan Zhang; Carmine Zoccali; Vincenzo Trischitta
Joint effect of insulin signaling genes on cardiovascular events and on whole body and endothelial insulin resistance.
Atherosclerosis 2013;226(1):140-5.
2012: Claudia Menzaghi; Eleonora Morini; Lucia Salvemini; Ryan Thompson; Concetta De Bonis; Salvatore De Cosmo; Rosa Di Paola; Alessandro Doria; Grazia Fini; Maddalena Giorelli; Davide Mangiacotti; Vincenzo Trischitta
Serum resistin and kidney function: a family-based study in non-diabetic, untreated individuals.
PloS one 2012;7(6):e38414.
2011: Salvatore De Cosmo; Rosa Di Paola; Olga Lamacchia; Emanuela Lapice; Eleonora Morini; Sabrina Prudente; Giuseppe Remuzzi; Piero Ruggenenti; Mauro Cignarelli; Massimiliano Copetti; Olga Vaccaro; Vincenzo Trischitta
PPARγ2 P12A polymorphism and albuminuria in patients with type 2 diabetes: a meta-analysis of case-control studies.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2011;26(12):4011-6.
2011: Rosa Di Paola; Nunzia Caporarello; Antonella Marucci; Claudia Dimatteo; Claudia Iadicicco; Silvia Del Guerra; Sabrina Prudente; Dora Sudano; Claudia Miele; Cristina Parrino; Salvatore Piro; Francesco Beguinot; Piero Marchetti; Vincenzo Trischitta; Lucia Frittitta
ENPP1 affects insulin action and secretion: evidences from in vitro studies.
PloS one 2011;6(5):e19462.
2009: Simonetta Bacci; Rosa Di Paola; Claudia Menzaghi; Patrizia Di Fulvio; Sara Di Silvestre; Fabio Pellegrini; Roberto Baratta; Antonella Marucci; Sandra Mastroianno; Grazia Fini; Gloria Formoso; agostino consoli; Francesco Perticone; Lucia Frittitta; Assunta Pandolfi; Vincenzo Trischitta
ENPP1 Q121 variant, increased pulse pressure and reduced insulin signaling, and nitric oxide synthase activity in endothelial cells.
Arteriosclerosis, thrombosis, and vascular biology 2009;29(10):1678-83.
2009: Antonella Marucci; Giuseppe Miscio; Libera Padovano; Watip Boonyasrisawat; Jose C Florez; Alessandro Doria; Vincenzo Trischitta; Rosa Di Paola
The role of HSP70 on ENPP1 expression and insulin-receptor activation.
Journal of molecular medicine (Berlin, Germany) 2009;87(2):139-44.
2007: Ornella Ludovico; Fabio Pellegrini; Rosa Di Paola; Antonio Minenna; Sandra Mastroianno; Marina Cardellini; Maria Adelaide Marini; Francesco Andreozzi; Olga Vaccaro; Giorgio Sesti; Vincenzo Trischitta
Heterogeneous effect of peroxisome proliferator-activated receptor gamma2 Ala12 variant on type 2 diabetes risk.
Obesity (Silver Spring, Md.) 2007;15(5):1076-81.
2007: Francesco Perticone; Raffaele Maio; Rosa Di Paola; Angela Sciacqua; Antonella Marucci; Salvatore De Cosmo; Maria Perticone; Giorgio Sesti; Vincenzo Trischitta
Role of PC-1 and ACE genes on insulin resistance and cardiac mass in never-treated hypertensive patients. Suggestive evidence for a digenic additive modulation.
Nutrition, metabolism, and cardiovascular diseases : NMCD 2007;17(3):181-7.
2006: Teresa Soccio; yuan-yuan zhang; Simonetta Bacci; Wojciech M Mlynarski; Grzegorz Placha; Greer Raggio; Rosa Di Paola; Antonella Marucci; Michael T Johnstone; Ernest V Gervino; Nada A Abumrad; Samuel Klein; Vincenzo Trischitta; Alessandro Doria
Common haplotypes at the adiponectin receptor 1 (ADIPOR1) locus are associated with increased risk of coronary artery disease in type 2 diabetes.
Diabetes 2006;55(10):2763-70.
2006: Rosa Di Paola; Ester Ciociola; Watip Boonyasrisawat; David Nolan; Jill Duffy; Giuseppe Miscio; Carmela Cisternino; Grazia Fini; Vittorio Tassi; Alessandro Doria; Vincenzo Trischitta
Association of hGrb10 genetic variations with type 2 diabetes in Caucasian subjects.
Diabetes care 2006;29(5):1181-3.
2005: Simonetta Bacci; Ornella Ludovico; Sabrina Prudente; yuan-yuan zhang; Rosa Di Paola; Davide Mangiacotti; Anna Rauseo; David Nolan; Jill Duffy; Grazia Fini; Lucia Salvemini; Cesare Amico; Carlo Vigna; Fabio Pellegrini; Claudia Menzaghi; Alessandro Doria; Vincenzo Trischitta
The K121Q polymorphism of the ENPP1/PC-1 gene is associated with insulin resistance/atherogenic phenotypes, including earlier onset of type 2 diabetes and myocardial infarction.
Diabetes 2005;54(10):3021-5.
2005: Rosa Di Paola; Vittorio Tassi; Vincenzo Trischitta
Reply to Dahlman et al. No association of reported functional protein tyrosine phosphatase 1B 3'UTR gene polymorphism with features of the metabolic syndrome in a Swedish population. J Int Med 2004; 255: 694-5.
Journal of internal medicine 2005;258(3):289-90; author reply 290.
2005: Claudia Menzaghi; Tonino Ercolino; Lucia Salvemini; Angelo Coco; Grazia Fini; Rosa Di Paola; Alessandro Doria; Vincenzo Trischitta
Lack of evidence for interaction between APM1 and PPARgamma2 genes in modulating insulin sensitivity in nondiabetic Caucasians from Italy.
Journal of internal medicine 2005;257(3):315-7.
2005: Angela Bulotta; Ornella Ludovico; Angelo Coco; Rosa Di Paola; Alessandro Quattrone; Massimo Carella; Fabio Pellegrini; Sabrina Prudente; Vincenzo Trischitta
The common -866G/A polymorphism in the promoter region of the UCP-2 gene is associated with reduced risk of type 2 diabetes in Caucasians from Italy.
The Journal of clinical endocrinology and metabolism 2005;90(2):1176-80.
2004: Salvatore De Cosmo; Antonella Marucci; E Ciociola; Rosa Di Paola; L Pucci; Giuseppe Penno; Stefano Del Prato; Giampiero Piras; Roberto Trevisan; S Giunti; Giancarlo Viberti; Vincenzo Trischitta
Lack of evidence for the 1484insG variant at the 3'-UTR of the protein tyrosine phosphatase 1B (PTP1B) gene as a genetic determinant of diabetic nephropathy development in type 1 diabetic patients.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2004;19(9):2419-20.
2004: Giuseppe Miscio; Vittorio Tassi; Angelo Coco; Teresa Soccio; Rosa Di Paola; Sabrina Prudente; Roberto Baratta; Lucia Frittitta; Ornella Ludovico; Libera Padovano; Bruno Dallapiccola; Umberto Di Mario; Salvatore De Cosmo; Vincenzo Trischitta
The allelic variant of LAR gene promoter -127 bp T-->A is associated with reduced risk of obesity and other features related to insulin resistance.
Journal of molecular medicine (Berlin, Germany) 2004;82(7):459-66.
2003: Roberto Baratta; Rosa Di Paola; Daniela Spampinato; Grazia Fini; Antonella Marucci; Angelo Coco; Riccardo Vigneri; Lucia Frittitta; Vincenzo Trischitta
Evidence for genetic epistasis in human insulin resistance: the combined effect of PC-1 (K121Q) and PPARgamma2 (P12A) polymorphisms.
Journal of molecular medicine (Berlin, Germany) 2003;81(11):718-23.
2003: Claudia Menzaghi; Rosa Di Paola; Germano Baj; Ada Funaro; Alberto Arnulfo; Tonino Ercolino; Nicola Surico; Fabio Malavasi; Vincenzo Trischitta
Insulin modulates PC-1 processing and recruitment in cultured human cells.
American journal of physiology. Endocrinology and metabolism 2003;284(3):E514-20.
2002: Antonio Pizzuti; Alessandra Argiolas; Rosa Di Paola; Roberto Baratta; Anna Rauseo; Maura Bozzali; Riccardo Vigneri; Bruno Dallapiccola; Vincenzo Trischitta; Lucia Frittitta
An ATG repeat in the 3'-untranslated region of the human resistin gene is associated with a decreased risk of insulin resistance.
The Journal of clinical endocrinology and metabolism 2002;87(9):4403-6.
2002: Claudia Menzaghi; Tonino Ercolino; Rosa Di Paola; Anders H Berg; James H Warram; Philipp E Scherer; Vincenzo Trischitta; Alessandro Doria
A haplotype at the adiponectin locus is associated with obesity and other features of the insulin resistance syndrome.
Diabetes 2002;51(7):2306-12.
2002: Rosa Di Paola; Maria Grazia Santagati; Giuseppe Miscio; Maura Bozzali; Roberto Baratta; Marta Centra; Daniela Spampinato; Maria Santagati; Tonino Ercolino; Carmela Cisternino; Teresa Soccio; Sandra Mastroianno; Vittorio Tassi; Peter Almgren; Antonio Pizzuti; Riccardo Vigneri; Vincenzo Trischitta
A variation in 3' UTR of hPTP1B increases specific gene expression and associates with insulin resistance.
American journal of human genetics 2002;70(3):806-12.
2001: Lucia Frittitta; Roberto Baratta; Daniela Spampinato; Rosa Di Paola; Antonio Pizzuti; Riccardo Vigneri; Vincenzo Trischitta
The Q121 PC-1 variant and obesity have additive and independent effects in causing insulin resistance.
The Journal of clinical endocrinology and metabolism 2001;86(12):5888-91.
2001: Maria Grazia Santagati; Tonino Ercolino; Maura Bozzali; Alessandra Argiolas; S Graci; Maria Santagati; Daniela Spampinato; Rosa Di Paola; Carmela Cisternino; Vittorio Tassi; Riccardo Vigneri; Antonio Pizzuti; Vincenzo Trischitta
A cluster of three single nucleotide polymorphisms in the 3'-untranslated region of human glycoprotein PC-1 gene stabilizes PC-1 mRNA and is associated with increased PC-1 protein content and insulin resistance-related abnormalities.
Diabetes 2001;50(8):1952-5.
2001: BV Costanzo; Vincenzo Trischitta; Rosa Di Paola; Daniela Spampinato; Antonio Pizzuti; Riccardo Vigneri; Lucia Frittitta
The Q allele variant (GLN121) of membrane glycoprotein PC-1 interacts with the insulin receptor and inhibits insulin signaling more effectively than the common K allele variant (LYS121).
Diabetes 2001;50(4):831-6.
1999: Alfredo Di Cerbo; Rosa Di Paola; Claudia Menzaghi; V De Filippis; K Tahara; D Corda; L D Kohn
Graves' immunoglobulins activate phospholipase A2 by recognizing specific epitopes on thyrotropin receptor.
The Journal of clinical endocrinology and metabolism 1999;84(9):3283-92.
1997: Rosa Di Paola; Claudia Menzaghi; V De Filippis; D Corda; Alfredo Di Cerbo
Cyclooxygenase-dependent thyroid cell proliferation induced by immunoglobulins from patients with Graves' disease.
The Journal of clinical endocrinology and metabolism 1997;82(2):670-3.
1995: Alfredo Di Cerbo; Rosa Di Paola; M Bonati; Matteo Zingrillo; V De Filippis; Daniela Corda
Subgroups of Graves' patients identified on the basis of the biochemical activities of their immunoglobulins.
The Journal of clinical endocrinology and metabolism 1995;80(9):2785-90.