Giuseppina Di Stefano

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Boga Carla; Fiume Luigi; Baglioni Michele; Bertucci Carlo; Farina Claudio; Kratz Felix; Manerba Marcella; Naldi Marina; Di Stefano Giuseppina
Characterisation of the conjugate of the (6-maleimidocaproyl)hydrazone derivative of doxorubicin with lactosaminated human albumin by 13C NMR spectroscopy.
Balietti Marta; Fattoretti Patrizia; Giorgetti Belinda; Casoli Tiziana; Di Stefano Giuseppina; Solazzi Moreno; Platano Daniela; Aicardi Giorgio; Bertoni-Freddari Carlo
A ketogenic diet increases succinic dehydrogenase activity in aging cardiomyocytes.
Bertoni-Freddari Carlo; Fattoretti Patrizia; Casoli Tiziana; Di Stefano Giuseppina; Balietti Marta; Giorgetti Belinda; Perretta Gemma
Neuronal apoptosis in Alzheimer's disease: the role of age-related mitochondrial metabolic competence.

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2009: Boga Carla; Fiume Luigi; Baglioni Michele; Bertucci Carlo; Farina Claudio; Kratz Felix; Manerba Marcella; Naldi Marina; Di Stefano Giuseppina
Characterisation of the conjugate of the (6-maleimidocaproyl)hydrazone derivative of doxorubicin with lactosaminated human albumin by 13C NMR spectroscopy.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2009;38(3):262-9.
2009: Balietti Marta; Fattoretti Patrizia; Giorgetti Belinda; Casoli Tiziana; Di Stefano Giuseppina; Solazzi Moreno; Platano Daniela; Aicardi Giorgio; Bertoni-Freddari Carlo
A ketogenic diet increases succinic dehydrogenase activity in aging cardiomyocytes.
Annals of the New York Academy of Sciences 2009;1171():377-84.
2009: Bertoni-Freddari Carlo; Fattoretti Patrizia; Casoli Tiziana; Di Stefano Giuseppina; Balietti Marta; Giorgetti Belinda; Perretta Gemma
Neuronal apoptosis in Alzheimer's disease: the role of age-related mitochondrial metabolic competence.
Annals of the New York Academy of Sciences 2009;1171():18-24.
2009: Fiume L; Baglioni M; Busi C; Manerba M; Di Stefano G
The enhancement of interstitial transport of a doxorubicin-lactosaminated albumin conjugate by imatinib: in rat hepatocellular carcinoma it is not preferentially higher than that in liver and bone marrow.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2009;72(3):630-1.
2008: Baglioni M; Fiume L; Bolondi L; Farina C; Kratz F; Di Stefano G
Binding of the doxorubicin-lactosaminated human albumin conjugate to HCC cells is mediated by the drug moieties.
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2008;40(12):963-4.
2008: Fiume Luigi; Baglioni Michele; Bolondi Luigi; Farina Claudio; Di Stefano Giuseppina
Doxorubicin coupled to lactosaminated human albumin: a hepatocellular carcinoma targeted drug.
Drug discovery today 2008;13(21-22):1002-9.
2008: Casoli Tiziana; Di Stefano Giuseppina
Comment on "Expression of amyloid beta peptide in human platelets: pivotal role of the phospholipase C gamma2-protein kinase C pathway in platelet activation" by Shen et al.
Pharmacological research : the official journal of the Italian Pharmacological Society 2008;58(1):85.
2008: Balietti Marta; Giorgetti Belinda; Fattoretti Patrizia; Grossi Yessica; Di Stefano Giuseppina; Casoli Tiziana; Platano Daniela; Solazzi Moreno; Orlando Fiorenza; Aicardi Giorgio; Bertoni-Freddari Carlo
Ketogenic diets cause opposing changes in synaptic morphology in CA1 hippocampus and dentate gyrus of late-adult rats.
Rejuvenation research 2008;11(3):631-40.
2008: Bertoni-Freddari Carlo; Fattoretti Patrizia; Casoli Tiziana; Di Stefano Giuseppina; Giorgetti Belinda; Balietti Marta
Brain aging: The zinc connection.
Experimental gerontology 2008;43(5):389-93.
2008: Platano Daniela; Fattoretti Patrizia; Balietti Marta; Giorgetti Belinda; Casoli Tiziana; Di Stefano Giuseppina; Bertoni-Freddari Carlo; Aicardi Giorgio
Synaptic remodeling in hippocampal CA1 region of aged rats correlates with better memory performance in passive avoidance test.
Rejuvenation research 2008;11(2):341-8.
2008: Bertoni-Freddari Carlo; Sensi Stefano L; Giorgetti Belinda; Balietti Marta; Di Stefano Giuseppina; Canzoniero Lorella M T; Casoli Tiziana; Fattoretti Patrizia
Decreased presence of perforated synapses in a triple-transgenic mouse model of Alzheimer's disease.
Rejuvenation research 2008;11(2):309-13.
2008: Bertoni-Freddari Carlo; Balietti Marta; Giorgetti Belinda; Grossi Yessica; Casoli Tiziana; Di Stefano Giuseppina; Perretta Gemma; Fattoretti Patrizia
Selective decline of the metabolic competence of oversized synaptic mitochondria in the old monkey cerebellum.
Rejuvenation research 2008;11(2):387-91.
2008: Di Stefano G; Fiume L; Baglioni M; Bolondi L; Chieco P; Kratz F; Pariali M; Rubini G
Efficacy of doxorubicin coupled to lactosaminated albumin on rat hepatocellular carcinomas evaluated by ultrasound imaging.
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2008;40(4):278-84.
2008: Casoli Tiziana; Di Stefano Giuseppina; Giorgetti Belinda; Balietti Marta; Recchioni Rina; Moroni Fausto; Marcheselli Fiorella; Bernardini Gianni; Fattoretti Patrizia; Bertoni-Freddari Carlo
Platelet as a physiological model to investigate apoptotic mechanisms in Alzheimer beta-amyloid peptide production.
Mechanisms of ageing and development 2008;129(3):154-62.
2008: Di Stefano Giuseppina; Fiume Luigi; Baglioni Michele; Busi Corrado; Bolondi Luigi; Farina Claudio; Mori Filippo; Chieco Pasquale; Pariali Milena; Kratz Felix; Molin Laura; Salmaso Stefano; Caliceti Paolo
Doxorubicin coupled to lactosaminated albumin: effect of heterogeneity in drug load on conjugate disposition and hepatocellular carcinoma uptake in rats.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2008;33(2):191-8.
2007: Bertoni-Freddari Carlo; Fattoretti Patrizia; Giorgetti Belinda; Grossi Yessica; Balietti Marta; Casoli Tiziana; Di Stefano Giuseppina; Perretta Gemma
Synaptic and mitochondrial morphometry provides structural correlates of successful brain aging.
Annals of the New York Academy of Sciences 2007;1097():51-3.
2007: Di Stefano Giuseppina; Fiume Luigi; Baglioni Michele; Busi Corrado; Chieco Pasquale; Kratz Felix; Mattioli Alessandro
Coupling of lactose molecules to the carrier protein hinders the spleen and bone marrow uptake of doxorubicin conjugated with human albumin.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2007;30(2):136-42.
2007: Casoli Tiziana; Di Stefano Giuseppina; Giorgetti Belinda; Grossi Yessica; Balietti Marta; Fattoretti Patrizia; Bertoni-Freddari Carlo
Release of beta-amyloid from high-density platelets: implications for Alzheimer's disease pathology.
Annals of the New York Academy of Sciences 2007;1096():170-8.
2007: Bertoni-Freddari Carlo; Fattoretti Patrizia; Giorgetti Belinda; Grossi Yessica; Balietti Marta; Casoli Tiziana; Di Stefano Giuseppina; Perretta Gemma
Preservation of mitochondrial volume homeostasis at the early stages of age-related synaptic deterioration.
Annals of the New York Academy of Sciences 2007;1096():138-46.
2007: Bertoni-Freddari Carlo; Fattoretti Patrizia; Giorgetti Belinda; Grossi Yessica; Balietti Marta; Casoli Tiziana; Di Stefano Giuseppina; Perretta Gemma
Alterations of synaptic turnover rate in aging may trigger senile plaque formation and neurodegeneration.
Annals of the New York Academy of Sciences 2007;1096():128-37.
2006: Fattoretti Patrizia; Bertoni-Freddari Carlo; Recchioni Rina; Giorgetti Belinda; Balietti Marta; Grossi Yessica; Solazzi Moreno; Casoli Tiziana; Di Stefano Giuseppina; Marcheselli Fiorella
Experimental apoptosis provides clues about the role of mitochondrial changes in neuronal death.
Annals of the New York Academy of Sciences 2006;1090():79-88.
2006: Bertoni-Freddari Carlo; Fattoretti Patrizia; Casoli Tiziana; Di Stefano Giuseppina; Solazzi Moreno; Perna Elisa; De Angelis Clara
Reactive structural dynamics of synaptic mitochondria in ischemic delayed neuronal death.
Annals of the New York Academy of Sciences 2006;1090():26-34.
2006: Di Stefano Giuseppina; Fiume Luigi; Baglioni Michele; Bolondi Luigi; Busi Corrado; Chieco Pasquale; Kratz Felix; Manaresi Francesca; Pariali Milena
A conjugate of doxorubicin with lactosaminated albumin enhances the drug concentrations in all the forms of rat hepatocellular carcinomas independently of their differentiation grade.
Liver international : official journal of the International Association for the Study of the Liver 2006;26(6):726-33.
2006: Di Stefano G; Fiume L; Domenicali M; Busi C; Chieco P; Kratz F; Lanza M; Mattioli A; Pariali M; Bernardi M
Doxorubicin coupled to lactosaminated albumin: Effects on rats with liver fibrosis and cirrhosis.
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2006;38(6):404-8.
2006: Bertoni-Freddari Carlo; Mocchegiani Eugenio; Malavolta Marco; Casoli Tiziana; Di Stefano Giuseppina; Fattoretti Patrizia
Synaptic and mitochondrial physiopathologic changes in the aging nervous system and the role of zinc ion homeostasis.
Mechanisms of ageing and development 2006;127(6):590-6.
2006: Di Stefano G; Busi C; Fiume L; Chieco P; Pariali M
Doxorubicin coupled to lactosaminated albumin: enhanced drug levels in rat hepatocarcinomas.
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2006;38(4):284-5.
2006: Fattoretti Patrizia; Balietti Marta; Giorgetti Belinda; Grossi Yessica; Casoli Tiziana; Di Stefano Giuseppina; Bertoni-Freddari Carlo
Testing mitochondrial metabolic competence by cytochrome oxidase preferential cytochemistry versus immunoreactivity of subunits I and IV.
Rejuvenation research 2006;9(2):215-8.
2006: Bertoni-Freddari Carlo; Fattoretti Patrizia; Giorgetti Belinda; Grossi Yessica; Casoli Tiziana; Di Stefano Giuseppina; Balietti Marta
Cytochemical estimation of cytochrome oxidase activity as a morphofunctional mitochondrial check-up.
Rejuvenation research 2006;9(2):202-6.
2006: Platano D; Bertoni-Freddari C; Fattoretti P; Giorgetti B; Grossi Y; Balietti M; Casoli T; Di Stefano G; Aicardi G
Structural synaptic remodeling in the perirhinal cortex of adult and old rats following object-recognition visual training.
Rejuvenation research 2006;9(1):102-6.
2006: Di Stefano Giuseppina; Casoli Tiziana; Fattoretti Patrizia; Balietti Marta; Grossi Yessica; Giorgetti Belinda; Bertoni-Freddari Carlo
Level and distribution of microtubule-associated protein-2 (MAP2) as an index of dendritic structural dynamics.
Rejuvenation research 2006;9(1):94-8.
2006: Bertoni-Freddari Carlo; Fattoretti Patrizia; Giorgetti Belinda; Grossi Yessica; Balietti Marta; Casoli Tiziana; Di Stefano Giuseppina; Perretta Gemma
Synaptic pathology in the brain cortex of old monkeys as an early alteration in senile plaque formation.
Rejuvenation research 2006;9(1):85-8.
2005: Fiume Luigi; Bolondi Luigi; Busi Corrado; Chieco Pasquale; Kratz Felix; Lanza Marcella; Mattioli Alessandro; Di Stefano Giuseppina
Doxorubicin coupled to lactosaminated albumin inhibits the growth of hepatocellular carcinomas induced in rats by diethylnitrosamine.
Journal of hepatology 2005;43(4):645-52.
2005: Di Stefano Giuseppina; Fiume Luigi; Bolondi Luigi; Lanza Marcella; Pariali Milena; Chieco Pasquale
Enhanced uptake of lactosaminated human albumin by rat hepatocarcinomas: implications for an improved chemotherapy of primary liver tumors.
Liver international : official journal of the International Association for the Study of the Liver 2005;25(4):854-60.
2004: Di Stefano Giuseppina; Lanza Marcella; Kratz Felix; Merina Luca; Fiume Luigi
A novel method for coupling doxorubicin to lactosaminated human albumin by an acid sensitive hydrazone bond: synthesis, characterization and preliminary biological properties of the conjugate.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2004;23(4-5):393-7.
2004: Casoli Tiziana; Di Stefano Giuseppina; Delfino Alessia; Fattoretti Patrizia; Bertoni-Freddari Carlo
Vitamin E deficiency and aging effect on expression levels of GAP-43 and MAP-2 in selected areas of the brain.
Annals of the New York Academy of Sciences 2004;1019():37-40.
2004: Bertoni-Freddari Carlo; Fattoretti Patrizia; Giorgetti Belinda; Solazzi Moreno; Balietti Marta; Casoli Tiziana; Di Stefano Giuseppina
Cytochrome oxidase activity in hippocampal synaptic mitochondria during aging: a quantitative cytochemical investigation.
Annals of the New York Academy of Sciences 2004;1019():33-6.
2004: Bertoni-Freddari Carlo; Fattoretti Patrizia; Giorgetti Belinda; Solazzi Moreno; Balietti Marta; Di Stefano Giuseppina; Casoli Tiziana
Decay of mitochondrial metabolic competence in the aging cerebellum.
Annals of the New York Academy of Sciences 2004;1019():29-32.
2004: Di Stefano Giuseppina; Derenzini Massimo; Kratz Felix; Lanza Marcella; Fiume Luigi
Liver-targeted doxorubicin: effects on rat regenerating hepatocytes.
Liver international : official journal of the International Association for the Study of the Liver 2004;24(3):246-52.
2003: Bertoni-Freddari Carlo; Fattoretti Patrizia; Solazzi Moreno; Giorgetti Belinda; Di Stefano Giuseppina; Casoli Tiziana; Meier-Ruge William
Neuronal death versus synaptic pathology in Alzheimer's disease.
Annals of the New York Academy of Sciences 2003;1010():635-8.
2003: Fattoretti P; Bertoni-Freddari C; Casoli T; Di Stefano G; Giorgetti G; Solazzi M
Ethanol-induced decrease of the expression of glucose transport protein (Glut3) in the central nervous system as a predisposing condition to apoptosis: the effect of age.
Annals of the New York Academy of Sciences 2003;1010():500-3.
2003: Di Stefano G; Kratz F; Lanza M; Fiume L
Doxorubicin coupled to lactosaminated human albumin remains confined within mouse liver cells after the intracellular release from the carrier.
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2003;35(6):428-33.
2003: Di Stefano Giuseppina; Tubaro Michela; Lanza Marcella; Boga Carla; Fiume Luigi; Traldi Pietro
Synthesis and physicochemical characteristics of a liver-targeted conjugate of fluorodeoxyuridine monophosphate with lactosaminated human albumin.
Rapid communications in mass spectrometry : RCM 2003;17(22):2503-7.
2002: Casoli T; Di Stefano G; Fattoretti P; Delfino A; Solazzi M; Bertoni-Freddari C
Effects of ethanol on GAP-43 levels in hippocampus and cerebellum of aged rats.
Annals of the New York Academy of Sciences 2002;973():313-6.
2002: Fattoretti Patrizia; Bertoni-Freddari Carlo; Casoli Tiziana; Di Stefano Giuseppina; Solazzi Moreno; Giorgetti Belinda
Decreased expression of glucose transport protein (Glut3) in aging and vitamin E deficiency.
Annals of the New York Academy of Sciences 2002;973():293-6.
2002: Casoli Tiziana; Di Stefano Guiseppina; Delfino Alessia; Solazzi Moreno; Fattoretti Patrizia; Bertoni-Freddari Carlo; Guidi Marco; Scarpino Osvaldo; Giunta Sergio; Galeazzi Luciano
Beta-amyloid fragment 25-35 selectively damages platelets from patients with Alzheimer's disease.
Annals of the New York Academy of Sciences 2002;977():296-302.
2002: Di Stefano G; Busi C; Fiume L
Floxuridine coupling with lactosaminated human albumin to increase drug efficacy on liver micrometastases.
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2002;34(6):439-46.
2002: Bertoni-Freddari Carlo; Fattoretti Patrizia; Casoli Tiziana; Di Stefano Giuseppina; Solazzi Moreno; Corvi Elena
Morphometric investigations of the mitochondrial damage in ceroid lipopigment accumulation due to vitamin E deficiency.
Archives of gerontology and geriatrics 2002;34(3):269-74.
2002: Fattoretti Patrizia; Bertoni-Freddari Carlo; Casoli Tiziana; Di Stefano Giuseppina; Solazzi Moreno; Corvi Elena
Morphometry of age pigment (lipofuscin) and of ceroid pigment deposits associated with vitamin E deficiency.
Archives of gerontology and geriatrics 2002;34(3):263-8.
2002: Di Stefano Giuseppina; Lanza Marcella; Busi Corrado; Barbieri Luigi; Fiume Luigi
Conjugates of nucleoside analogs with lactosaminated human albumin to selectively increase the drug levels in liver blood: requirements for a regional chemotherapy.
The Journal of pharmacology and experimental therapeutics 2002;301(2):638-42.
2001: Casoli T; Di Stefano G; Gracciotti N; Fattoretti P; Solazzi M; Bertoni-Freddari C
Age-related effects of moderate alcohol consumption on GAP-43 levels in rat hippocampus.
Mechanisms of ageing and development 2001;122(15):1723-38.
2001: Casoli T; Di Stefano G; Gracciotti N; Giovagnetti S; Fattoretti P; Solazzi M; Bertoni-Freddari C
Cellular distribution of GAP-43 mRNA in hippocampus and cerebellum of adult rat brain by in situ RT-PCR.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2001;49(9):1195-6.
2001: Bertoni-Freddari C; Fattoretti P; Casoli T; Di Stefano G; Solazzi M; Gracciotti N; Pompei P
Mapping of mitochondrial metabolic competence by cytochrome oxidase and succinic dehydrogenase cytochemistry.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2001;49(9):1191-2.
2001: Di Stefano G; Casoli T; Fattoretti P; Gracciotti N; Solazzi M; Bertoni-Freddari C
Distribution of map2 in hippocampus and cerebellum of young and old rats by quantitative immunohistochemistry.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2001;49(8):1065-6.
2001: Bertoni-Freddari C; Fattoretti P; Casoli T; Di Stefano G; Solazzi M; Meier-Ruge W
Quantitative cytochemical mapping of mitochondrial enzymes in rat cerebella.
Micron (Oxford, England : 1993) 2001;32(4):405-10.
2001: Fattoretti P; Bertoni-Freddari C; Di Stefano G; Casoli T; Gracciotti N; Solazzi M; Pompei P
Quantitative immunohistochemistry of glucose transport protein (Glut3) expression in the rat hippocampus during aging.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2001;49(5):671-2.
2001: Di Stefano G; Busi C; Camerino A; Derenzini M; Trerè D; Fiume L
Coupling of 5-fluoro 2'-deoxyuridine to lactosaminated poly-l-lysine: an approach to a regional, non-invasive chemotherapy of liver micrometastases.
Biochemical pharmacology 2001;61(4):459-65.
2000: Bertoni-Freddari C; Casoli T; Fattoretti P; Galeazzi L; Di Stefano G; Belardinelli N; Pucci E; Signorino M
Cytochemistry of intraplatelet Ca++ spots as a peripheral marker of age-related brain impairment.
Annals of the New York Academy of Sciences 2000;903():164-6.
2000: Di Stefano G; Busi C; Camerino A; Nardo B; Fiume L
Enhanced liver blood concentrations of adenine arabinoside accomplished by lactosaminated poly-L-lysine coupling: implications for regional chemotherapy of hepatic micrometastases.
Biochemical pharmacology 2000;59(3):301-4.
1999: Trerè D; Fiume L; De Giorgi L B; Di Stefano G; Migaldi M; Derenzini M
The asialoglycoprotein receptor in human hepatocellular carcinomas: its expression on proliferating cells.
British journal of cancer 1999;81(3):404-8.
1999: Di Stefano G; Busi C; Mattioli A; Derenzini M; Trerè D; Fiume L
Inhibition of [3H]thymidine incorporation into DNA of rat regenerating liver by 2',2'-difluorodeoxycytidine coupled to lactosaminated poly-L-lysine.
Biochemical pharmacology 1999;57(7):793-9.
1998: Fiume L; Di Stefano G; Busi C; Incitti F; Rapicetta M; Farina C; Gervasi G B; Bonino F
Coupling to lactosaminated poly-L-lysine reduces the toxic effects of ribavirin on red blood cells.
Journal of hepatology 1998;29(6):1032-3.
1998: Di Stefano G; Busi C; Derenzini M; Trerè D; Fiume L
Conjugation of 5-fluoro-2'-deoxyuridine with lactosaminated poly-l-lysine to reduce extrahepatic toxicity in the treatment of hepatocarcinomas.
Italian journal of gastroenterology and hepatology 1998;30(2):173-7.
1997: Di Stefano G; Bignamini A; Busi C; Colonna F P; Fiume L
Enhanced accumulation of ribavirin and its metabolites in liver versus erythrocytes in mice administered with the liver targeted drug.
Italian journal of gastroenterology and hepatology 1997;29(5):420-6.
1997: Di Stefano G; Colonna F P; Bongini A; Busi C; Mattioli A; Fiume L
Ribavirin conjugated with lactosaminated poly-L-lysine: selective delivery to the liver and increased antiviral activity in mice with viral hepatitis.
Biochemical pharmacology 1997;54(3):357-63.
1997: Fiume L; Di Stefano G; Busi C; Mattioli A; Battista Gervasi G; Bertini M; Bartoli C; Catalani R; Caccia G; Farina C; Fissi A; Pieroni O; Giuseppetti R; D'Ugo E; Bruni R; Rapicetta M
Hepatotropic conjugate of adenine arabinoside monophosphate with lactosaminated poly-L-lysine. Synthesis of the carrier and pharmacological properties of the conjugate.
Journal of hepatology 1997;26(2):253-9.
1997: Fiume L; Di Stefano G; Busi C; Mattioli A; Bonino F; Torrani-Cerenzia M; Verme G; Rapicetta M; Bertini M; Gervasi G B
Liver targeting of antiviral nucleoside analogues through the asialoglycoprotein receptor.
Journal of viral hepatitis 1997;4(6):363-70.
1996: Torrani Cerenzia M; Fiume L; De Bernardi Venon W; Lavezzo B; Brunetto M R; Ponzetto A; Di Stefano G; Busi C; Mattioli A; Gervasi G B; Bonino F; Verme G
Adenine arabinoside monophosphate coupled to lactosaminated human albumin administered for 4 weeks in patients with chronic type B hepatitis decreased viremia without producing significant side effects.
Hepatology (Baltimore, Md.) 1996;23(4):657-61.
1995: Fiume L; Di Stefano G; Busi C; Mattioli A; Rapicetta M; Giuseppetti R; Ciccaglione A R; Argentini C
Inhibition of woodchuck hepatitis virus replication by adenine arabinoside monophosphate coupled to lactosaminated poly-L-lysine and administered by intramuscular route.
Hepatology (Baltimore, Md.) 1995;22(4 Pt 1):1072-7.
1995: Di Stefano G; Busi C; Mattioli A; Fiume L
Selective delivery to the liver of antiviral nucleoside analogs coupled to a high molecular mass lactosaminated poly-L-lysine and administered to mice by intramuscular route.
Biochemical pharmacology 1995;49(12):1769-75.
1995: Fiume L; Busi C; Di Stefano G; Mattioli A; Torrani-Cerenzia M; Bonino F; Capra G; De Bernardi W; Ponzetto A; Lavezzo B
Liver targeting of adenine arabinoside monophosphate (ara-AMP) by coupling to lactosaminated human serum albumin.
The Italian journal of gastroenterology 1995;27(4):189-92.
1994: Fiume L; Busi C; Corzani S; Di Stefano G; Gervasi G B; Mattioli A
Organ distribution of a conjugate of adenine arabinoside monophosphate with lactosaminated albumin in the rat.
Journal of hepatology 1994;20(5):681-2.
1994: Torrani Cerenzia M R; Fiume L; Busi C; Mattioli A; Di Stefano G; Gervasi G B; Brunetto M R; Piantino P; Verme G; Bonino F
Inhibition of hepatitis B virus replication by adenine arabinoside monophosphate coupled to lactosaminated albumin. Efficacy and minimal active dose.
Journal of hepatology 1994;20(2):307-9.
1994: Fiume L; Di Stefano G; Busi C; Mattioli A
A conjugate of lactosaminated poly-L-lysine with adenine arabinoside monophosphate, administered to mice by intramuscular route, accomplishes a selective delivery of the drug to the liver.
Biochemical pharmacology 1994;47(4):643-50.
1993: Fiume L; Busi C; Di Stefano G; Mattioli A
Coupling of antiviral nucleoside analogs to lactosaminated human albumin by using the imidazolides of their phosphoric esters.
Analytical biochemistry 1993;212(2):407-11.
1992: Fiume L; Betts C M; Busi C; Corzani S; Derenzini M; Di Stefano G; Mattioli A
The pathogenesis of vacuoles produced in rat and mouse liver cells by a conjugate of adenine arabinoside monophosphate with lactosaminated albumin.
Journal of hepatology 1992;15(3):314-22.
1991: Dall'Olio F; Malagolini N; Di Stefano G; Ciambella M; Serafini-Cessi F
Alpha 2,6 sialylation of N-acetyllactosaminic sequences in human colorectal cancer cell lines. Relationship with non-adherent growth.
International journal of cancer. Journal international du cancer 1991;47(2):291-7.
1991: Fiume L; Mattioli A; Busi C; Corzani S; Di Stefano G
High-pressure liquid chromatographic method for determining adenine arabinoside monophosphate coupled to lactosaminated albumin in plasma.
Pharmaceutica acta Helvetiae 1991;66(8):230-2.
1990: Dall'Olio F; Malagolini N; Di Stefano G; Ciambella M; Serafini-Cessi F
Postnatal development of rat colon epithelial cells is associated with changes in the expression of the beta 1,4-N-acetylgalactosaminyltransferase involved in the synthesis of Sda antigen of alpha 2,6-sialyltransferase activity towards N-acetyl-lactosamine.
The Biochemical journal 1990;270(2):519-24.
1989: Malagolini N; Dall'Olio F; Di Stefano G; Minni F; Marrano D; Serafini-Cessi F
Expression of UDP-GalNAc:NeuAc alpha 2,3Gal beta-R beta 1,4(GalNAc to Gal) N-acetylgalactosaminyltransferase involved in the synthesis of Sda antigen in human large intestine and colorectal carcinomas.
Cancer research 1989;49(23):6466-70.
1989: Dall'Olio F; Malagolini N; di Stefano G; Minni F; Marrano D; Serafini-Cessi F
Increased CMP-NeuAc:Gal beta 1,4GlcNAc-R alpha 2,6 sialyltransferase activity in human colorectal cancer tissues.
International journal of cancer. Journal international du cancer 1989;44(3):434-9.

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