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Indu Ambudkar

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Luyuan Jin; Xibao Liu; Lizheng Qin; Indu S Ambudkar; Dajun Deng; Zhipeng Fan; Liankun Gu; Junqi He; Dengsheng Xia; Chunmei Zhang; Songlin Wang
Active secretion and protective effect of salivary nitrate against stress in human volunteers and rats.
Biswaranjan Pani; Hemal H Patel; Changyu Zheng; Virginia R Achen; Indu S Ambudkar; Sunitha Bollimuntha; Kwong Tai Cheng; Xibao Liu; Ingrid R Niesman; Brij B Singh
Impairment of TRPC1-STIM1 channel assembly and AQP5 translocation compromise agonist-stimulated fluid secretion in mice lacking caveolin1.
Kwong Tai Cheng; Stefan Feske; Xibao Liu; Masatsugu Oh-hora; William D Swaim; Hongen Yin; Ilias Alevizos; Indu S Ambudkar
STIM1 and STIM2 protein deficiency in T lymphocytes underlies development of the exocrine gland autoimmune disease, Sjogren's syndrome.

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2013: Luyuan Jin; Xibao Liu; Lizheng Qin; Indu S Ambudkar; Dajun Deng; Zhipeng Fan; Liankun Gu; Junqi He; Dengsheng Xia; Chunmei Zhang; Songlin Wang
Active secretion and protective effect of salivary nitrate against stress in human volunteers and rats.
Free radical biology & medicine 2013;57():61-7.
2013: Biswaranjan Pani; Hemal H Patel; Changyu Zheng; Virginia R Achen; Indu S Ambudkar; Sunitha Bollimuntha; Kwong Tai Cheng; Xibao Liu; Ingrid R Niesman; Brij B Singh
Impairment of TRPC1-STIM1 channel assembly and AQP5 translocation compromise agonist-stimulated fluid secretion in mice lacking caveolin1.
Journal of cell science 2013;126(Pt 2):667-75.
2012: Kwong Tai Cheng; Stefan Feske; Xibao Liu; Masatsugu Oh-hora; William D Swaim; Hongen Yin; Ilias Alevizos; Indu S Ambudkar
STIM1 and STIM2 protein deficiency in T lymphocytes underlies development of the exocrine gland autoimmune disease, Sjogren's syndrome.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(36):14544-9.
2012: Bidhan Bandyopadhyay; Xibao Liu; Ankana Sarkar; William D Swaim; Indu S Ambudkar
Extracellular Ca(2+) sensing in salivary ductal cells.
The Journal of biological chemistry 2012;287(36):30305-16.
2012: Lizheng Qin; Qifei Sun; Dengsheng Xia; Chunmei Zhang; Changyu Zheng; David Adams; Indu S Ambudkar; Dajun Deng; Gang Ding; Zhipeng Fan; William A Gahl; Liankun Gu; Junqi He; Luyuan Jin; Xibao Liu; Hwei Ling Ong; Senrong Qi; Songlin Wang
Sialin (SLC17A5) functions as a nitrate transporter in the plasma membrane.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(33):13434-9.
2012: Hwei Ling Ong; Shyh-Ing Jang; Indu S Ambudkar
Distinct contributions of Orai1 and TRPC1 to agonist-induced [Ca(2+)](i) signals determine specificity of Ca(2+)-dependent gene expression.
PloS one 2012;7(10):e47146.
2012: Francesco Lodola; Mariangela Manzoni; Margherita Massa; Francesco Moccia; Hwei Ling Ong; Paolo Pedrazzoli; Vittorio Rosti; Franco Tanzi; Indu S Ambudkar; Elisa Bonetti; Cinzia Bottino; Silvia Dragoni; Carlo Ganini; Armando A Genazzani; Germano Guerra; Umberto Laforenza; Dmitry Lim; Camillo Porta
Store-operated Ca2+ entry is remodelled and controls in vitro angiogenesis in endothelial progenitor cells isolated from tumoral patients.
PloS one 2012;7(9):e42541.
2011: Xin Ma; Roger G O'Neil; Ching On Wong; Indu S Ambudkar; Lutz Birnbaumer; Kwong Tai Cheng; Xiaoqiang Yao
Heteromeric TRPV4-C1 channels contribute to store-operated Ca(2+) entry in vascular endothelial cells.
Cell calcium 2011;50(6):502-9.
2011: Hwei Ling Ong; Indu S Ambudkar
The dynamic complexity of the TRPC1 channelosome.
Channels (Austin, Tex.) 2011;5(5):424-31.
2011: Indu S Ambudkar
Dissection of calcium signaling events in exocrine secretion.
Neurochemical research 2011;36(7):1212-21.
2011: Kwong Tai Cheng; Xibao Liu; Hwei Ling Ong; William D Swaim; Indu S Ambudkar
Local Ca²+ entry via Orai1 regulates plasma membrane recruitment of TRPC1 and controls cytosolic Ca²+ signals required for specific cell functions.
PLoS biology 2011;9(3):e1001025.
2011: Jeong Hee Hong; Qin Li; Min Seuk Kim; Dong Min Shin; Stefan Feske; Lutz Birnbaumer; Kwong Tai Cheng; Indu S Ambudkar; Shmuel Muallem
Polarized but differential localization and recruitment of STIM1, Orai1 and TRPC channels in secretory cells.
Traffic (Copenhagen, Denmark) 2011;12(2):232-45.
2011: Kwong Tai Cheng; Hwei Ling Ong; Xibao Liu; Indu S Ambudkar
Contribution of TRPC1 and Orai1 to Ca(2+) entry activated by store depletion.
Advances in experimental medicine and biology 2011;704():435-49.
2010: Xin Ma; Jingyuan Cao; Jianhong Luo; Bernd Nilius; Yu Huang; Indu S Ambudkar; Xiaoqiang Yao
Depletion of intracellular Ca2+ stores stimulates the translocation of vanilloid transient receptor potential 4-c1 heteromeric channels to the plasma membrane.
Arteriosclerosis, thrombosis, and vascular biology 2010;30(11):2249-55.
2010: Xibao Liu; Hwei Ling Ong; Biswaranjan Pani; Katherine Johnson; William B Swaim; Brij Singh; Indu S Ambudkar
Effect of cell swelling on ER/PM junctional interactions and channel assembly involved in SOCE.
Cell calcium 2010;47(6):491-9.
2010: Bradford E Hall; Changyu Zheng; William D Swaim; Andrew Cho; Chandrasekharam N Nagineni; Michael A Eckhaus; Kathleen C Flanders; Indu S Ambudkar; Bruce J Baum; Ashok B Kulkarni
Conditional overexpression of TGF-beta1 disrupts mouse salivary gland development and function.
Laboratory investigation; a journal of technical methods and pathology 2010;90(4):543-55.
2009: Biswaranjan Pani; Hwei Ling Ong; So-Ching W Brazer; Xibao Liu; Kristina Rauser; Brij B Singh; Indu S Ambudkar
Activation of TRPC1 by STIM1 in ER-PM microdomains involves release of the channel from its scaffold caveolin-1.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(47):20087-92.
2009: Indu S Ambudkar
Unraveling smooth muscle contraction: the TRP link.
Gastroenterology 2009;137(4):1211-4.
2008: Bidhan Bandyopadhyay; Hwei Ling Ong; Timothy P Lockwich; Xibao Liu; Biman C Paria; Brij B Singh; Indu S Ambudkar
TRPC3 controls agonist-stimulated intracellular Ca2+ release by mediating the interaction between inositol 1,4,5-trisphosphate receptor and RACK1.
The Journal of biological chemistry 2008;283(47):32821-30.
2008: Biswaranjan Pani; Hwei Ling Ong; Xibao Liu; Kristina Rauser; Indu S Ambudkar; Brij B Singh
Lipid rafts determine clustering of STIM1 in endoplasmic reticulum-plasma membrane junctions and regulation of store-operated Ca2+ entry (SOCE).
The Journal of biological chemistry 2008;283(25):17333-40.
2008: Kwong Tai Cheng; Xibao Liu; Hwei Ling Ong; Indu S Ambudkar
Functional requirement for Orai1 in store-operated TRPC1-STIM1 channels.
The Journal of biological chemistry 2008;283(19):12935-40.
2008: Timothy P Lockwich; Jaya Pant; Anthony Makusky; Ewa Jankowska-Stephens; Jeffrey A Kowalak; Sanford Markey; Indu S Ambudkar
Analysis of TRPC3-interacting proteins by tandem mass spectrometry.
Journal of proteome research 2008;7(3):979-89.
2007: Indu S Ambudkar; Hwei Ling Ong
Organization and function of TRPC channelosomes.
Pflügers Archiv : European journal of physiology 2007;455(2):187-200.
2007: Xibao Liu; Kwong Tai Cheng; Bidhan Bandyopadhyay; Biswaranjan Pani; Alexander Dietrich; Biman C Paria; William D Swaim; David Beech; Eda Yildrim; Brij B Singh; Lutz Birnbaumer; Indu S Ambudkar
Attenuation of store-operated Ca2+ current impairs salivary gland fluid secretion in TRPC1(-/-) mice.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(44):17542-7.
2007: Indu S Ambudkar; Hwei Ling Ong; Xibao Liu; Bidhan Bandyopadhyay; Bidhan Bandyopadhyay; Kwong Tai Cheng
TRPC1: the link between functionally distinct store-operated calcium channels.
Cell calcium 2007;42(2):213-23.
2007: János Vág; Elaine M Byrne; Deirdre H Hughes; Matthew Hoffman; Indu S Ambudkar; Paula Maguire; Brian C O'Connell
Morphological and functional differentiation of HSG cells: role of extracellular matrix and trpc 1.
Journal of cellular physiology 2007;212(2):416-23.
2007: Seshagiri R Nandula; Shoba Amarnath; Alfredo A Molinolo; Bidhan Bandyopadhyay; Bradford Hall; Corinne M Goldsmith; Changyu Zheng; Jonas Larsson; Taduru Sreenath; WanJun Chen; Indu S Ambudkar; Stefan Karlsson; Bruce J Baum; Ashok Kulkarni
Female mice are more susceptible to developing inflammatory disorders due to impaired transforming growth factor beta signaling in salivary glands.
Arthritis and rheumatism 2007;56(6):1798-805.
2007: Hwei Ling Ong; Xibao Liu; Krasimira Tsaneva-Atanasova; Brij B Singh; Bidhan Bandyopadhyay; William D Swaim; James T Russell; Ramanujan S Hegde; Arthur Sherman; Indu S Ambudkar
Relocalization of STIM1 for activation of store-operated Ca(2+) entry is determined by the depletion of subplasma membrane endoplasmic reticulum Ca(2+) store.
The Journal of biological chemistry 2007;282(16):12176-85.
2007: Hwei Ling Ong; Kwong Tai Cheng; Xibao Liu; Bidhan Bandyopadhyay; Biman C Paria; Jonathan Soboloff; Biswaranjan Pani; Yousang Gwack; Sonal Srikanth; Brij B Singh; Donald L Gill; Donald Gill; Indu S Ambudkar
Dynamic assembly of TRPC1-STIM1-Orai1 ternary complex is involved in store-operated calcium influx. Evidence for similarities in store-operated and calcium release-activated calcium channel components.
The Journal of biological chemistry 2007;282(12):9105-16.
2007: Hwei Ling Ong; Xibao Liu; Ajay Sharma; Ramanujan S Hegde; Indu S Ambudkar
Intracellular Ca(2+) release via the ER translocon activates store-operated calcium entry.
Pflügers Archiv : European journal of physiology 2007;453(6):797-808.
2006: Indu S Ambudkar; Bidhan Bandyopadhyay; Xibao Liu; Timothy P Lockwich; Biman C Paria; Hwei Ling Ong
Functional organization of TRPC-Ca2+ channels and regulation of calcium microdomains.
Cell calcium 2006;40(5-6):495-504.
2006: Biswaranjan Pani; Eric Cornatzer; William Cornatzer; Dong-Min Shin; Mark Pittelkow; Alain Hovnanian; Indu S Ambudkar; Brij B Singh
Up-regulation of transient receptor potential canonical 1 (TRPC1) following sarco(endo)plasmic reticulum Ca2+ ATPase 2 gene silencing promotes cell survival: a potential role for TRPC1 in Darier's disease.
Molecular biology of the cell 2006;17(10):4446-58.
2006: Xibao Liu; Bidhan Bandyopadhyay; Bidhan Bandyopadhyay; Tetsuji Nakamoto; Brij Singh; Wolfgang Liedtke; James E Melvin; Indu S Ambudkar
A role for AQP5 in activation of TRPV4 by hypotonicity: concerted involvement of AQP5 and TRPV4 in regulation of cell volume recovery.
The Journal of biological chemistry 2006;281(22):15485-95.
2006: Indu S Ambudkar
Ca2+ signaling microdomains:platforms for the assembly and regulation of TRPC channels.
Trends in pharmacological sciences 2006;27(1):25-32.
2005: Chinopoulos Christos; anatoly starkov; Sergey Grigoriev; Laurent M Dejean; Kathleen W Kinnally; Xibao Liu; Indu S Ambudkar; Gary Fiskum
Diacylglycerols activate mitochondrial cationic channel(s) and release sequestered Ca(2+).
Journal of bioenergetics and biomembranes 2005;37(4):237-47.
2005: Xibao Liu; Bidhan Bandyopadhyay; Brij B Singh; Klaus Groschner; Indu S Ambudkar
Molecular analysis of a store-operated and 2-acetyl-sn-glycerol-sensitive non-selective cation channel. Heteromeric assembly of TRPC1-TRPC3.
The Journal of biological chemistry 2005;280(22):21600-6.
2005: Bidhan Bandyopadhyay; William D Swaim; Xibao Liu; Robert S Redman; Randen L Patterson; Indu S Ambudkar
Apical localization of a functional TRPC3/TRPC6-Ca2+-signaling complex in polarized epithelial cells. Role in apical Ca2+ influx.
The Journal of biological chemistry 2005;280(13):12908-16.
2005: Alessandra Fiorio Pla; Dragan Maric; So-Ching Brazer; Paolo Giacobini; Xibao Liu; Yoong Hee Chang; Indu S Ambudkar; Jeffery L Barker
Canonical transient receptor potential 1 plays a role in basic fibroblast growth factor (bFGF)/FGF receptor-1-induced Ca2+ entry and embryonic rat neural stem cell proliferation.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(10):2687-701.
2004: Brij B Singh; Timothy P Lockwich; Bidhan Bandyopadhyay; Xibao Liu; Sunitha Bollimuntha; So-Ching Brazer; Christian Combs; Sunit Das; Miriam Leenders; Zu-Hang Sheng; Mark A Knepper; Suresh V Ambudkar; Indu S Ambudkar
VAMP2-dependent exocytosis regulates plasma membrane insertion of TRPC3 channels and contributes to agonist-stimulated Ca2+ influx.
Molecular cell 2004;15(4):635-46.
2004: Indu S Ambudkar
Cellular domains that contribute to Ca2+ entry events.
Science's STKE : signal transduction knowledge environment 2004;2004(243):pe32.
2004: Xibao Liu; Klaus Groschner; Indu S Ambudkar
Distinct Ca(2+)-permeable cation currents are activated by internal Ca(2+)-store depletion in RBL-2H3 cells and human salivary gland cells, HSG and HSY.
The Journal of membrane biology 2004;200(2):93-104.
2004: Yoko Dohke; Young S Oh; Indu S Ambudkar; R James Turner
Biogenesis and topology of the transient receptor potential Ca2+ channel TRPC1.
The Journal of biological chemistry 2004;279(13):12242-8.
2004: Indu S Ambudkar; So-Ching Brazer; Xibao Liu; Timothy P Lockwich; Brij Singh
Plasma membrane localization of TRPC channels: role of caveolar lipid rafts.
Novartis Foundation symposium 2004;258():63-70; discussion 70-4, 98-102, 263-6.
2003: So-Ching Brazer; Brij B Singh; Xibao Liu; William D Swaim; Indu S Ambudkar
Caveolin-1 contributes to assembly of store-operated Ca2+ influx channels by regulating plasma membrane localization of TRPC1.
The Journal of biological chemistry 2003;278(29):27208-15.
2003: Xibao Liu; Brij B Singh; Indu S Ambudkar
TRPC1 is required for functional store-operated Ca2+ channels. Role of acidic amino acid residues in the S5-S6 region.
The Journal of biological chemistry 2003;278(13):11337-43.
2002: Radhika Basheer; Elda Arrigoni; Hemant S Thatte; Robert W Greene; Indu S Ambudkar; Robert W McCarley
Adenosine induces inositol 1,4,5-trisphosphate receptor-mediated mobilization of intracellular calcium stores in basal forebrain cholinergic neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(17):7680-6.
2002: Byung-Chul Kim; Heung Tae Kim; Mizuko Mamura; Indu S Ambudkar; Kyeong Sook Choi; Seong-Jin Kim
Tumor necrosis factor induces apoptosis in hepatoma cells by increasing Ca(2+) release from the endoplasmic reticulum and suppressing Bcl-2 expression.
The Journal of biological chemistry 2002;277(35):31381-9.
2002: Zhi-Hui Xie; Indu S Ambudkar; Reuben P Siraganian
The adapter molecule Gab2 regulates Fc epsilon RI-mediated signal transduction in mast cells.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(9):4682-91.
2002: Brij B Singh; Xibao Liu; Jisen Tang; Michael X Zhu; Indu S Ambudkar
Calmodulin regulates Ca(2+)-dependent feedback inhibition of store-operated Ca(2+) influx by interaction with a site in the C terminus of TrpC1.
Molecular cell 2002;9(4):739-50.
2001: Timothy P Lockwich; Brij B Singh; Xibao Liu; Indu S Ambudkar
Stabilization of cortical actin induces internalization of transient receptor potential 3 (Trp3)-associated caveolar Ca2+ signaling complex and loss of Ca2+ influx without disruption of Trp3-inositol trisphosphate receptor association.
The Journal of biological chemistry 2001;276(45):42401-8.
2001: Xibao Liu; Indu S Ambudkar
Characteristics of a store-operated calcium-permeable channel: sarcoendoplasmic reticulum calcium pump function controls channel gating.
The Journal of biological chemistry 2001;276(32):29891-8.
2001: Brij B Singh; Changyu Zheng; Xibao Liu; Timothy P Lockwich; D Liao; Michael X Zhu; Lutz Birnbaumer; Indu S Ambudkar
Trp1-dependent enhancement of salivary gland fluid secretion: role of store-operated calcium entry.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(9):1652-4.
2001: Xibao Liu; D Liao; Indu S Ambudkar
Distinct mechanisms of [Ca2+]i oscillations in HSY and HSG cells: role of Ca2+ influx and internal Ca2+ store recycling.
The Journal of membrane biology 2001;181(3):185-93.
2000: Brij B Singh; Xibao Liu; Indu S Ambudkar
Expression of truncated transient receptor potential protein 1alpha (Trp1alpha ): evidence that the Trp1 C terminus modulates store-operated Ca2+ entry.
The Journal of biological chemistry 2000;275(47):36483-6.
2000: Timothy P Lockwich; Xibao Liu; Brij B Singh; J Jadlowiec; S Weiland; Indu S Ambudkar
Assembly of Trp1 in a signaling complex associated with caveolin-scaffolding lipid raft domains.
The Journal of biological chemistry 2000;275(16):11934-42.
2000: A T M Shamsul Hoque; Xibao Liu; H Kagami; William D Swaim; Robert B Wellner; Brian C O'Connell; Indu S Ambudkar; Bruce J Baum
Construction and function of a recombinant adenovirus encoding a human aquaporin 1-green fluorescent protein fusion product.
Cancer gene therapy 2000;7(3):476-85.
2000: Xibao Liu; W Wang; Brij B Singh; Timothy P Lockwich; J Jadlowiec; B O'Connell; Robert B Wellner; Michael X Zhu; Indu S Ambudkar
Trp1, a candidate protein for the store-operated Ca(2+) influx mechanism in salivary gland cells.
The Journal of biological chemistry 2000;275(5):3403-11.
2000: Indu S Ambudkar
Regulation of calcium in salivary gland secretion.
Critical reviews in oral biology and medicine : an official publication of the American Association of Oral Biologists 2000;11(1):4-25.
1999: Laura Masiero; KA Lapidos; Indu S Ambudkar; Elise C Kohn
Regulation of the RhoA pathway in human endothelial cell spreading on type IV collagen: role of calcium influx.
Journal of cell science 1999;112 ( Pt 19)():3205-13.
1999: Y Xu; Indu S Ambudkar; H Yamagishi; William D Swaim; THOMAS WALSH; Brian C O'Connell
Histatin 3-mediated killing of Candida albicans: effect of extracellular salt concentration on binding and internalization.
Antimicrobial agents and chemotherapy 1999;43(9):2256-62.
1999: Xibao Liu; Brij B Singh; Indu S Ambudkar
ATP-dependent activation of K(Ca) and ROMK-type K(ATP) channels in human submandibular gland ductal cells.
The Journal of biological chemistry 1999;274(35):25121-9.
1999: W Wang; B O'Connell; R Dykeman; Takayoshi Sakai; Christine Delporte; William D Swaim; X Zhu; Lutz Birnbaumer; Indu S Ambudkar
Cloning of Trp1beta isoform from rat brain: immunodetection and localization of the endogenous Trp1 protein.
The American journal of physiology 1999;276(4 Pt 1):C969-79.
1999: AC O'Connell; Robert S Redman; RL Evans; Indu S Ambudkar
Radiation-induced progressive decrease in fluid secretion in rat submandibular glands is related to decreased acinar volume and not impaired calcium signaling.
Radiation research 1999;151(2):150-8.
1998: Xibao Liu; AC O'Connell; Indu S Ambudkar
Ca2+-dependent inactivation of a store-operated Ca2+ current in human submandibular gland cells. Role of a staurosporine-sensitive protein kinase and the intracellular Ca2+ pump.
The Journal of biological chemistry 1998;273(50):33295-304.
1998: AC O'Connell; CD Lillibridge; Changyu Zheng; Bruce J Baum; Brian C O'Connell; Indu S Ambudkar
Gamma-irradiation-induced cell cycle arrest and cell death in a human submandibular gland cell line: effect of E2F1 expression.
Journal of cellular physiology 1998;177(2):264-73.
1998: Xibao Liu; E Rojas; Indu S Ambudkar
Regulation of KCa current by store-operated Ca2+ influx depends on internal Ca2+ release in HSG cells.
The American journal of physiology 1998;275(2 Pt 1):C571-80.
1998: Brian C O'Connell; CD Lillibridge; Indu S Ambudkar; D Kruse
Somatic gene transfer to salivary glands.
Annals of the New York Academy of Sciences 1998;842():171-80.
1998: J V Chauthaiwale; Timothy P Lockwich; Indu S Ambudkar
Characteristics of a low affinity passive Ca2+ influx component in rat parotid gland basolateral plasma membrane vesicles.
The Journal of membrane biology 1998;162(2):139-45.
1997: S Meehan; Angela Janet Wu; E C Kang; Takayoshi Sakai; Indu S Ambudkar
Interferon-gamma induces a decrease in the intracellular calcium pump in a human salivary gland cell line.
The American journal of physiology 1997;273(6 Pt 1):C2030-6.
1997: Takayoshi Sakai; Indu S Ambudkar
Role for protein kinase in Ca2+-dependent feedback modulation of divalent cation influx in internal-Ca2+-store-depleted rat parotid gland cells.
Pflügers Archiv : European journal of physiology 1997;433(4):464-71.
1996: Christine Delporte; Brian C O'Connell; X He; Indu S Ambudkar; Peter Agre; Bruce J Baum
Adenovirus-mediated expression of aquaporin-5 in epithelial cells.
The Journal of biological chemistry 1996;271(36):22070-5.
1996: V J Horn; RS Redman; Indu S Ambudkar
Response of rat salivary glands to mastication of pelleted vitamin A-deficient diet.
Archives of oral biology 1996;41(8-9):769-77.
1996: Takayoshi Sakai; Indu S Ambudkar
Role for protein phosphatase in the regulation of Ca2+ influx in parotid gland acinar cells.
The American journal of physiology 1996;271(1 Pt 1):C284-94.
1996: J V Chauthaiwale; Takayoshi Sakai; S E Taylor; Indu S Ambudkar
Presence of two Ca2+ influx components in internal Ca2+-pool-depleted rat parotid acinar cells.
Pflügers Archiv : European journal of physiology 1996;432(1):105-11.
1996: Angela Janet Wu; Z J Chen; M Tsokos; Brian C O'Connell; Indu S Ambudkar; Bruce J Baum
Interferon-gamma induced cell death in a cultured human salivary gland cell line.
Journal of cellular physiology 1996;167(2):297-304.
1996: Angela Janet Wu; Z J Chen; Bruce J Baum; Indu S Ambudkar
Interferon-gamma induces persistent depletion of internal Ca2+ stores in a human salivary gland cell line.
The American journal of physiology 1996;270(2 Pt 1):C514-21.
1995: T Lockwich; J Chauthaiwale; S V Ambudkar; Indu S Ambudkar
Reconstitution of a passive Ca(2+)-transport pathway from the basolateral plasma membrane of rat parotid gland acinar cells.
The Journal of membrane biology 1995;148(3):277-85.
1995: K Sawaki; Bruce J Baum; G S Roth; Indu S Ambudkar
Decreased m3-muscarinic and alpha 1-adrenergic receptor stimulation of PIP2 hydrolysis in parotid gland membranes from aged rats: defect in activation of G alpha q/11.
Archives of biochemistry and biophysics 1995;322(2):319-26.
1995: K Sawaki; Bruce J Baum; Indu S Ambudkar
Alpha 1-adrenergic and m3-muscarinic receptor stimulation of phosphatidylinositol 4,5-bisphosphate-specific phospholipase C are independently mediated by G alpha q/11 in rat parotid gland membranes.
Archives of biochemistry and biophysics 1995;316(1):535-40.
1994: M D Kaplan; S E Taylor; Indu S Ambudkar
G-protein- and capacitatively regulated Ca2+ entry pathways are activated by muscarinic receptor stimulation in a human submandibular ductal cell line.
Pflügers Archiv : European journal of physiology 1994;428(5-6):439-45.
1994: T P Lockwich; I H Kim; Indu S Ambudkar
Temperature-dependent modification of divalent cation flux in the rat parotid gland basolateral membrane.
The Journal of membrane biology 1994;141(3):289-96.
1993: T Lockwich; L M Mertz; Indu S Ambudkar
Involvement of carboxyl groups in the divalent cation permeability of rat parotid gland basolateral plasma membrane.
Molecular and cellular biochemistry 1993;126(2):143-50.
1993: K Sawaki; Y Hiramatsu; Bruce J Baum; Indu S Ambudkar
Involvement of G alpha q/11 in m3-muscarinic receptor stimulation of phosphatidylinositol 4,5 bisphosphate-specific phospholipase C in rat parotid gland membranes.
Archives of biochemistry and biophysics 1993;305(2):546-50.
1993: T Lockwich; Indu S Ambudkar; Adil E Shamoo
Ca2+ permeability of rat parotid gland basolateral plasma membrane vesicles is modulated by membrane potential and extravesicular [Ca2+].
Membrane biochemistry 1993;10(3):171-9.
1993: Indu S Ambudkar; Y Hiramatsu; T Lockwich; Bruce J Baum
Activation and regulation of calcium entry in rat parotid gland acinar cells.
Critical reviews in oral biology and medicine : an official publication of the American Association of Oral Biologists 1993;4(3-4):421-5.
1993: Bruce J Baum; Y Dai; Y Hiramatsu; V J Horn; Indu S Ambudkar
Signaling mechanisms that regulate saliva formation.
Critical reviews in oral biology and medicine : an official publication of the American Association of Oral Biologists 1993;4(3-4):379-84.
1992: Chih-Ko Yeh; Indu S Ambudkar; E Kousvelari
Differential expression of early response genes, c-jun, c-fos, and jun B, in A5 cells.
The American journal of physiology 1992;263(6 Pt 1):G934-8.
1992: Indu S Ambudkar; T Lockwich; Y Hiramatsu; Bruce J Baum
Calcium entry in rat parotid acinar cells.
Molecular and cellular biochemistry 1992;114(1-2):73-7.
1992: Y Hiramatsu; Bruce J Baum; Indu S Ambudkar
Elevation of cytosolic [Ca2+] due to intracellular Ca2+ release retards carbachol stimulation of divalent cation entry in rat parotid gland acinar cells.
The Journal of membrane biology 1992;129(3):277-86.
1992: Y Hiramatsu; V J Horn; Bruce J Baum; Indu S Ambudkar
Characterization of polyphosphoinositide-specific phospholipase C in rat parotid gland membranes.
Archives of biochemistry and biophysics 1992;297(2):368-76.
1992: L M Mertz; Bruce J Baum; Indu S Ambudkar
Membrane potential modulates divalent cation entry in rat parotid acini.
The Journal of membrane biology 1992;126(2):183-93.
1991: Y S Dai; Indu S Ambudkar; V J Horn; Chih-Ko Yeh; E E Kousvelari; S J Wall; M Li; Robert P Yasuda; Barry B Wolfe; Bruce J Baum
Evidence that M3 muscarinic receptors in rat parotid gland couple to two second messenger systems.
The American journal of physiology 1991;261(6 Pt 1):C1063-73.
1991: V J Horn; Bruce J Baum; Indu S Ambudkar
Muscarinic receptor antagonist effects in parotid acini and M1-CHO cells: evidence of G protein involvement.
Biochemical and biophysical research communications 1991;177(2):784-9.
1991: Y Hiramatsu; Indu S Ambudkar; Bruce J Baum
Characterization of high affinity GTPase activity correlated to beta-adrenergic receptor stimulation of adenylyl cyclase in rat parotid membranes.
Biochimica et biophysica acta 1991;1092(3):391-6.
1991: V J Horn; Indu S Ambudkar; Bruce J Baum
High affinity quinuclidinyl benzilate binding to rat parotid membranes requires muscarinic receptor. G protein interactions.
FEBS letters 1991;282(2):289-92.
1991: V J Horn; P A Sheehy; M B Goodman; Indu S Ambudkar
Activation of the inositol trisphosphate second messenger system by cAMP in a mouse fibroblast cell line.
Molecular and cellular biochemistry 1991;101(1):43-9.
1990: Indu S Ambudkar; V J Horn; Y S Dai; Bruce J Baum
Evidence against a role for a pertussis toxin-sensitive G protein in Ca2+ mobilization in rat parotid acinar cells.
Biochimica et biophysica acta 1990;1055(3):259-64.
1990: L M Mertz; Bruce J Baum; Indu S Ambudkar
Refill status of the agonist-sensitive Ca2+ pool regulates Mn2+ influx into parotid acini.
The Journal of biological chemistry 1990;265(25):15010-4.
1990: L M Mertz; V J Horn; Bruce J Baum; Indu S Ambudkar
Calcium entry in rat parotid acini: activation by carbachol and aluminum fluoride.
The American journal of physiology 1990;258(4 Pt 1):C654-61.
1990: V J Horn; Bruce J Baum; Indu S Ambudkar
Attenuation of inositol trisphosphate generation and cytosolic Ca2+ elevation in dispersed rat parotid acini stimulated simultaneously at muscarinic and alpha 1-adrenergic receptors.
Biochemical and biophysical research communications 1990;166(2):967-72.
1990: Bruce J Baum; Indu S Ambudkar; Joseph I Helman; V J Horn; J E Melvin; L M Mertz; R James Turner
Dispersed salivary gland acinar cell preparations for use in studies of neuroreceptor-coupled secretory events.
Methods in enzymology 1990;192():26-37.
1989: V J Horn; Bruce J Baum; Indu S Ambudkar
Evidence for the convergence of beta-adrenergic and muscarinic signalling systems at a post-receptor site.
FEBS letters 1989;258(1):13-6.
1989: Indu S Ambudkar; V J Horn; Bruce J Baum
ATP-dependent Ca2+ transport in the rat parotid basolateral plasma membrane is regulated by calmodulin.
Archives of biochemistry and biophysics 1989;268(2):576-84.
1988: Bruce J Baum; Indu S Ambudkar; V J Horn
Evidence that ATP-dependent Ca2+ transport in rat parotid microsomal membranes requires charge compensation.
The Biochemical journal 1988;254(3):649-54.
1988: V J Horn; Bruce J Baum; Indu S Ambudkar
Beta-adrenergic receptor stimulation induces inositol trisphosphate production and Ca2+ mobilization in rat parotid acinar cells.
The Journal of biological chemistry 1988;263(25):12454-60.
1988: Bruce J Baum; Indu S Ambudkar
Regulation of calcium handling by rat parotid acinar cells.
Molecular and cellular biochemistry 1988;82(1-2):67-73.
1988: Indu S Ambudkar; J E Melvin; Bruce J Baum
Alpha 1-adrenergic regulation of Cl- and Ca2+ movements in rat parotid acinar cells.
Pflügers Archiv : European journal of physiology 1988;412(1-2):75-9.
1988: Indu S Ambudkar; Bruce J Baum
Modulation of ATP-dependent Ca2+ transport in rat parotid basolateral membrane vesicles by K+ + Cl- flux.
Biochimica et biophysica acta 1988;941(2):198-208.
1988: Indu S Ambudkar; Bruce J Baum
ATP-dependent calcium transport in rat parotid basolateral membrane vesicles is modulated by membrane potential.
The Journal of membrane biology 1988;102(1):59-69.
1988: Indu S Ambudkar; B L Kuyatt; G S Roth; Bruce J Baum
Modification of ATP-dependent Ca2+ transport in rat parotid basolateral membranes during aging.
Mechanisms of ageing and development 1988;43(1):45-60.
1987: Joseph I Helman; Indu S Ambudkar; Bruce J Baum
Adrenoreceptor mobilization of calcium in rat submandibular cells.
European journal of pharmacology 1987;143(1):65-72.