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Helén Dichek

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Rowan Flynn; Bo Jiang; Kun Qian; Chongren Tang; Shan Wen; Joshua M Buckler; Helén L Dichek; Nagadhara Dronadula; David A Dichek
Expression of apolipoprotein A-I in rabbit carotid endothelium protects against atherosclerosis.
Stephen D Farris; Elizabeth Gold; Jie Hong Hu; Michal Kremen; Ranjini Krishnan; Stephen A Ramsey; Talyn Chu; Helén L Dichek; Liang Du; Isaac Emery; David A Dichek
Mechanisms of urokinase plasminogen activator (uPA)-mediated atherosclerosis: role of the uPA receptor and S100A8/A9 proteins.
Harvey K Chiu; Kun Qian; Kayoko Ogimoto; Gregory J Morton; Brent E Wisse; Nalini Agrawal; Thomas O McDonald; Michael W Schwartz; Helén L Dichek
Mice lacking hepatic lipase are lean and protected against diet-induced obesity and hepatic steatosis.

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All Publications

2011: Rowan Flynn; Bo Jiang; Kun Qian; Chongren Tang; Shan Wen; Joshua M Buckler; Helén L Dichek; Nagadhara Dronadula; David A Dichek
Expression of apolipoprotein A-I in rabbit carotid endothelium protects against atherosclerosis.
Molecular therapy : the journal of the American Society of Gene Therapy 2011;19(10):1833-41.
2011: Stephen D Farris; Elizabeth Gold; Jie Hong Hu; Michal Kremen; Ranjini Krishnan; Stephen A Ramsey; Talyn Chu; Helén L Dichek; Liang Du; Isaac Emery; David A Dichek
Mechanisms of urokinase plasminogen activator (uPA)-mediated atherosclerosis: role of the uPA receptor and S100A8/A9 proteins.
The Journal of biological chemistry 2011;286(25):22665-77.
2010: Harvey K Chiu; Kun Qian; Kayoko Ogimoto; Gregory J Morton; Brent E Wisse; Nalini Agrawal; Thomas O McDonald; Michael W Schwartz; Helén L Dichek
Mice lacking hepatic lipase are lean and protected against diet-induced obesity and hepatic steatosis.
Endocrinology 2010;151(3):993-1001.
2009: Ranjini Krishnan; Michal Kremen; Jie Hong Hu; Isaac Emery; Stephen D Farris; Katherine I Slezicki; Talyn Chu; Liang Du; Helén L Dichek; David A Dichek
Level of macrophage uPA expression is an important determinant of atherosclerotic lesion growth in Apoe-/- mice.
Arteriosclerosis, thrombosis, and vascular biology 2009;29(11):1737-44.
2009: Andrew D Frutkin; Goro Otsuka; April Stempien-Otero; Casilde Sesti; Liang Du; Mia Jaffe; Helén L Dichek; Caroline J Pennington; Dylan R Edwards; Madeline Nieves-Cintrón; Daniel Minter; Michael Preusch; Jie Hong Hu; Julien C Marie; David A Dichek
TGF-[beta]1 limits plaque growth, stabilizes plaque structure, and prevents aortic dilation in apolipoprotein E-null mice.
Arteriosclerosis, thrombosis, and vascular biology 2009;29(9):1251-7.
2008: Sasha Taleban; Heather T Carew; Helén L Dichek; Samir S Deeb; David Hollenback; David S Weigle; David E Cummings; John D Brunzell
Energy balance in congenital generalized lipodystrophy type I.
Metabolism: clinical and experimental 2008;57(8):1155-61.
2008: Stephen M Eacker; Nalini Agrawal; Kun Qian; Helén L Dichek; Eun-Yeung Gong; Keesook Lee; Robert E Braun
Hormonal regulation of testicular steroid and cholesterol homeostasis.
Molecular endocrinology (Baltimore, Md.) 2008;22(3):623-35.
2007: Kun Qian; Nalini Agrawal; Helén L Dichek
Reduced atherosclerosis in chow-fed mice expressing high levels of a catalytically inactive human hepatic lipase.
Atherosclerosis 2007;195(1):66-74.
2006: Helén L Dichek; Nalini Agrawal; Nazim El Andaloussi; Kun Qian
Attenuated corticosterone response to chronic ACTH stimulation in hepatic lipase-deficient mice: evidence for a role for hepatic lipase in adrenal physiology.
American journal of physiology. Endocrinology and metabolism 2006;290(5):E908-15.
2004: Helén L Dichek; Kun Qian; Nalini Agrawal
Divergent effects of the catalytic and bridging functions of hepatic lipase on atherosclerosis.
Arteriosclerosis, thrombosis, and vascular biology 2004;24(9):1696-702.
2004: Aaron E Cozen; Hideaki Moriwaki; Michal Kremen; Mary Beth DeYoung; Helén L Dichek; Katherine I Slezicki; Stephen G Young; Murielle Véniant; David A Dichek
Macrophage-targeted overexpression of urokinase causes accelerated atherosclerosis, coronary artery occlusions, and premature death.
Circulation 2004;109(17):2129-35.
2004: Helén L Dichek; Kun Qian; Nalini Agrawal
The bridging function of hepatic lipase clears plasma cholesterol in LDL receptor-deficient "apoB-48-only" and "apoB-100-only" mice.
Journal of lipid research 2004;45(3):551-60.
2004: Tatsuro Ishida; Zhi Zheng; Helén L Dichek; Huijian Wang; Ismael Moreno; Eugene Yang; Ramendra K Kundu; Said Talbi; Ken-ichi Hirata; Lawrence L K Leung; Thomas Quertermous
Molecular cloning of nonsecreted endothelial cell-derived lipase isoforms.
Genomics 2004;83(1):24-33.
2001: Helén L Dichek; S M Johnson; H Akeefe; G T Lo; E Sage; C E Yap; Robert W Mahley
Hepatic lipase overexpression lowers remnant and LDL levels by a noncatalytic mechanism in LDL receptor-deficient mice.
Journal of lipid research 2001;42(2):201-10.
1999: Ken-ichi Hirata; Helén L Dichek; J A Cioffi; Sungshin Y Choi; N J Leeper; L Quintana; GS Kronmal; Allen D Cooper; Thomas Quertermous
Cloning of a unique lipase from endothelial cells extends the lipase gene family.
The Journal of biological chemistry 1999;274(20):14170-5.
1998: Helén L Dichek; Walter J Brecht; J Fan; Zhong-Sheng Ji; Sally P A McCormick; H Akeefe; L Conzo; David A Sanan; Karl H Weisgraber; Stephen G Young; John M Taylor; Robert W Mahley
Overexpression of hepatic lipase in transgenic mice decreases apolipoprotein B-containing and high density lipoproteins. Evidence that hepatic lipase acts as a ligand for lipoprotein uptake.
The Journal of biological chemistry 1998;273(4):1896-903.
1997: Zhong-Sheng Ji; Helén L Dichek; R Dennis Miranda; Robert W Mahley
Heparan sulfate proteoglycans participate in hepatic lipaseand apolipoprotein E-mediated binding and uptake of plasma lipoproteins, including high density lipoproteins.
The Journal of biological chemistry 1997;272(50):31285-92.