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Gerhard Dickneite

Research Profile

Chemicals & Drugs

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Publications

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Maulik D Majmudar; Marc W Nolte; Matt Sebas; Brena F Sena; Filip K Swirski; Jessica Truelove; Ralph Weissleder; Gregory Wojtkiewicz; Daniel G Anderson; Anna Borodovsky; John W Chen; Gabriel Courties; Gerhard Dickneite; Partha Dutta; Kevin Fitzgerald; Rostic Gorbatov; Timo Heidt; Yoshiko Iwamoto; Edmund J Keliher; Florian Leuschner; Matthias Nahrendorf
Monocyte-Directed RNAi Targeting CCR2 Improves Infarct Healing in Atherosclerosis-Prone Mice.
John W Chen; Gerhard Dickneite; Jose-Luiz Figueiredo; Yoshiko Iwamoto; Dong-Eog Kim; Marc W Nolte; Cory Siegel; Ralph Weissleder; Gregory R Wojtkiewicz; Matthias Nahrendorf
Selective factor XIIa inhibition attenuates silent brain ischemia: application of molecular imaging targeting coagulation pathway.
Nadine Heydenreich; Marion Hofmeister; Christiane Albert-Weissenberger; Marc Brede; Gerhard Dickneite; Eva Göb; Kerstin Göbel; Peter Kraft; Friederike Langhauser; Sven G Meuth; Bernhard Nieswandt; Marc W Nolte; Guido Stoll; Csanad Varallyay; Christoph Kleinschnitz
C1-inhibitor protects from brain ischemia-reperfusion injury by combined antiinflammatory and antithrombotic mechanisms.

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All Publications

2013: Maulik D Majmudar; Marc W Nolte; Matt Sebas; Brena F Sena; Filip K Swirski; Jessica Truelove; Ralph Weissleder; Gregory Wojtkiewicz; Daniel G Anderson; Anna Borodovsky; John W Chen; Gabriel Courties; Gerhard Dickneite; Partha Dutta; Kevin Fitzgerald; Rostic Gorbatov; Timo Heidt; Yoshiko Iwamoto; Edmund J Keliher; Florian Leuschner; Matthias Nahrendorf
Monocyte-Directed RNAi Targeting CCR2 Improves Infarct Healing in Atherosclerosis-Prone Mice.
Circulation 2013;127(20):2038-46.
2012: John W Chen; Gerhard Dickneite; Jose-Luiz Figueiredo; Yoshiko Iwamoto; Dong-Eog Kim; Marc W Nolte; Cory Siegel; Ralph Weissleder; Gregory R Wojtkiewicz; Matthias Nahrendorf
Selective factor XIIa inhibition attenuates silent brain ischemia: application of molecular imaging targeting coagulation pathway.
JACC. Cardiovascular imaging 2012;5(11):1127-38.
2012: Nadine Heydenreich; Marion Hofmeister; Christiane Albert-Weissenberger; Marc Brede; Gerhard Dickneite; Eva Göb; Kerstin Göbel; Peter Kraft; Friederike Langhauser; Sven G Meuth; Bernhard Nieswandt; Marc W Nolte; Guido Stoll; Csanad Varallyay; Christoph Kleinschnitz
C1-inhibitor protects from brain ischemia-reperfusion injury by combined antiinflammatory and antithrombotic mechanisms.
Stroke; a journal of cerebral circulation 2012;43(9):2457-67.
2011: Ikuko Tsujimoto; Gerhard Dickneite; Kei Moriya; Keiko Sakai; Takao Sakai
Critical role of factor XIII in the initial stages of carbon tetrachloride-induced adult liver remodeling.
The American journal of pathology 2011;179(6):3011-9.
2011: Torsten G Loof; Matthias Mörgelin; Anna Norrby-Teglund; Sonja Oehmcke; Anders I Olin; Ulrich Theopold; Gerhard Dickneite; Linda Johansson; Heiko Herwald
Coagulation, an ancestral serine protease cascade, exerts a novel function in early immune defense.
Blood 2011;118(9):2589-98.
2010: F Kaspereit; S Hoffmann; I Pragst; Gerhard Dickneite
Prothrombin complex concentrate mitigates diffuse bleeding after cardiopulmonary bypass in a porcine model.
British journal of anaesthesia 2010;105(5):576-82.
2010: Gerhard Dickneite; Bärbel Dörr; Franz Kaspereit; Kenichi A Tanaka
Prothrombin complex concentrate versus recombinant factor VIIa for reversal of hemodilutional coagulopathy in a porcine trauma model.
The Journal of trauma 2010;68(5):1151-7.
2010: Ina Hagedorn; Stefan Schmidbauer; Irina Pleines; Christoph Kleinschnitz; Ulrich Kronthaler; Guido Stoll; Gerhard Dickneite; Bernhard Nieswandt
Factor XIIa inhibitor recombinant human albumin Infestin-4 abolishes occlusive arterial thrombus formation without affecting bleeding.
Circulation 2010;121(13):1510-7.
2010: Ingo Pragst; Franz Kaspereit; Bärbel Dörr; Gerhard Dickneite
Prothrombin complex concentrate (Beriplex P/N) for control of bleeding after kidney trauma in a rabbit dilutional coagulopathy model.
Thrombosis research 2010;125(3):272-7.
2009: Gerhard Dickneite; Ingo Pragst; Christine Joch; Garrett E Bergman
Animal model and clinical evidence indicating low thrombogenic potential of fibrinogen concentrate (Haemocomplettan P).
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 2009;20(7):535-40.
2009: Gerhard Dickneite; I Pragst
Prothrombin complex concentrate vs fresh frozen plasma for reversal of dilutional coagulopathy in a porcine trauma model.
British journal of anaesthesia 2009;102(3):345-54.
2008: Gerhard Dickneite
A comparison of the pharmacokinetics of antithrombin derived from human plasma and from transgenic goats and the prevention of sepsis in an animal model.
Biopharmaceutics & drug disposition 2008;29(6):356-65.
2008: Gerhard Dickneite; Baerbel Doerr; Franz Kaspereit
Characterization of the coagulation deficit in porcine dilutional coagulopathy and substitution with a prothrombin complex concentrate.
Anesthesia and analgesia 2008;106(4):1070-7, table of contents.
2008: Kenichi A Tanaka; fania szlam; Gerhard Dickneite; Jerrold H Levy
Effects of prothrombin complex concentrate and recombinant activated factor VII on vitamin K antagonist induced anticoagulation.
Thrombosis research 2008;122(1):117-23.
2007: Gerhard Dickneite
Prothrombin complex concentrate versus recombinant factor VIIa for reversal of coumarin anticoagulation.
Thrombosis research 2007;119(5):643-51.
2006: Matthias Nahrendorf; Kai Hu; Stefan Frantz; Farouc A Jaffer; Ching-Hsuan Tung; Karl-Heinz Hiller; Sabine Voll; Peter Nordbeck; David E Sosnovik; Stefan Gattenlöhner; Mikhail Novikov; Gerhard Dickneite; Guy L Reed; Peter M Jakob; Anthony Rosenzweig; Wolfgang R Bauer; Ralph Weissleder; Georg Ertl
Factor XIII deficiency causes cardiac rupture, impairs wound healing, and aggravates cardiac remodeling in mice with myocardial infarction.
Circulation 2006;113(9):1196-202.
2006: Rima Dardik; Jonathan Leor; Ehud Skutelsky; David Castel; Radka Holbova; Ginette Schiby; Aviv Shaish; Gerhard Dickneite; Joseph Loscalzo; Aida Inbal
Evaluation of the pro-angiogenic effect of factor XIII in heterotopic mouse heart allografts and FXIII-deficient mice.
Thrombosis and haemostasis 2006;95(3):546-50.
2005: Shawn Jobe; Lorie Leo; Joshua S Eastvold; Gerhard Dickneite; Timothy L Ratliff; Steven R Lentz; Jorge Di Paola
Role of FcRgamma and factor XIIIA in coated platelet formation.
Blood 2005;106(13):4146-51.
2005: Monika Kroez; Wiegand Lang; Gerhard Dickneite
Wound healing and degradation of the fibrin sealant Beriplast P following partial liver resection in rabbits.
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 2005;13(3):318-23.
2004: Franz Kaspereit; Baerbel Doerr; Gerhard Dickneite
The effect of fibrinogen concentrate administration on coagulation abnormalities in a rat sepsis model.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 2004;15(1):39-43.
2003: Shiori Koseki-Kuno; Mitsunori Yamakawa; Gerhard Dickneite; Akitada Ichinose
Factor XIII A subunit-deficient mice developed severe uterine bleeding events and subsequent spontaneous miscarriages.
Blood 2003;102(13):4410-2.
2003: Monika Kroez; Ernst-Jürgen Kanzy; Peter Gronski; Gerhard Dickneite
Hypotension with intravenous immunoglobulin therapy: importance of pH and dimer formation.
Biologicals : journal of the International Association of Biological Standardization 2003;31(4):277-86.
2003: M Phillips; Gerhard Dickneite; Hubert J Metzner
Fibrin sealants in supporting surgical techniques: strength in factor XIII.
Cardiovascular surgery (London, England) 2003;11 Suppl 1():13-6.
2003: Gerhard Dickneite; Hubert J Metzner; Thomas Pfeifer; Monika Kroez; Günther Witzke
A comparison of fibrin sealants in relation to their in vitro and in vivo properties.
Thrombosis research 2003;112(1-2):73-82.
2002: Peter Lauer; Hubert J Metzner; Gerd Zettlmeissl; Meng Li; Austin G Smith; Richard Lathe; Gerhard Dickneite
Targeted inactivation of the mouse locus encoding coagulation factor XIII-A: hemostatic abnormalities in mutant mice and characterization of the coagulation deficit.
Thrombosis and haemostasis 2002;88(6):967-74.
2002: Gerhard Dickneite; Hubert J Metzner; Monika Kroez; Berndt Hein; Uwe Nicolay
The importance of factor XIII as a component of fibrin sealants.
The Journal of surgical research 2002;107(2):186-95.
2002: Jens M Hecker; Ralf Lorenz; Richard Appiah; Burkhard Vangerow; Martin Loss; Robert Kunz; Jan Schmidtko; Michael Mengel; Jürgen Klempnauer; Siegfried Piepenbrock; Gerhard Dickneite; Helge Neidhardt; Horst Rückoldt; Michael Winkler
C1-inhibitor for prophylaxis of xenograft rejection after pig to cynomolgus monkey kidney transplantation.
Transplantation 2002;73(5):688-94.
2001: Gerhard Dickneite; Monika Kroez
Treatment of porcine sepsis with high-dose antithrombin III reduces tissue edema and effusion but does not increase risk for bleeding.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 2001;12(6):459-67.
2000: Gerhard Dickneite; Hubert J Metzner; Uwe Nicolay
Prevention of suture hole bleeding using fibrin sealant: benefits of factor XIII.
The Journal of surgical research 2000;93(2):201-5.
1998: Gerhard Dickneite; Uwe Nicolay; H J Friesen; M Reers
Development of an anti-bleeding agent for recombinant hirudin induced skin bleeding in the pig.
Thrombosis and haemostasis 1998;80(1):192-8.
1996: Gerhard Dickneite; H J Friesen; G Kumpe; M Reers
Reduction of r-hirudin induced bleeding in pigs by the administration of von Willebrand factor.
Platelets 1996;7(5-6):283-90.