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Michael Didié

Research Profile

Procedures

Disorders

Myocardial Contraction

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Chemicals & Drugs

Physiology

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Publications

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Daniel Biermann; Rainer H Böger; Lucie Carrier; Michael Didié; Sonia Donzelli; Heimo Ehmke; Süleyman Ergün; Michael Grimm; Andreas Heilmann; Lutz Hein; Hermann Reichenspurner; Maria Römer; Saskia Schlossarek; Anna Steenpass; Karim R Sultan; Azadeh Wahab; Wolfram-Hubertus Zimmermann; Ralf A Benndorf
Impact of AT2 receptor deficiency on postnatal cardiovascular development.
Malte Tiburcy; Xiaoke Yin; Anke Zieseniss; Oliver Boy; Peter Christalla; Michael Didié; Stephan Döker; Ali El-Armouche; Thomas Eschenhagen; Michael Grimm; Nazha Hamdani; Bijoy Chandapillai Karikkineth; Doerthe M Katschinksi; Wolfgang A Linke; Manuel Mayr; Hiroshi Naito; Monika Nose; Wolfram-Hubertus Zimmermann
Terminal differentiation, advanced organotypic maturation, and modeling of hypertrophic growth in engineered heart tissue.
Cornelia Grebe; Theda-Maria Klingebiel; Simon Philipp Grau; Karl Toischer; Michael Didié; Claudius Jacobshagen; Christian Dullin; Gerd Hasenfuss; Tim Seidler
Enhanced expression of DYRK1A in cardiomyocytes inhibits acute NFAT activation but does not prevent hypertrophy in vivo.

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All Publications

2012: Daniel Biermann; Rainer H Böger; Lucie Carrier; Michael Didié; Sonia Donzelli; Heimo Ehmke; Süleyman Ergün; Michael Grimm; Andreas Heilmann; Lutz Hein; Hermann Reichenspurner; Maria Römer; Saskia Schlossarek; Anna Steenpass; Karim R Sultan; Azadeh Wahab; Wolfram-Hubertus Zimmermann; Ralf A Benndorf
Impact of AT2 receptor deficiency on postnatal cardiovascular development.
PloS one 2012;7(10):e47916.
2011: Malte Tiburcy; Xiaoke Yin; Anke Zieseniss; Oliver Boy; Peter Christalla; Michael Didié; Stephan Döker; Ali El-Armouche; Thomas Eschenhagen; Michael Grimm; Nazha Hamdani; Bijoy Chandapillai Karikkineth; Doerthe M Katschinksi; Wolfgang A Linke; Manuel Mayr; Hiroshi Naito; Monika Nose; Wolfram-Hubertus Zimmermann
Terminal differentiation, advanced organotypic maturation, and modeling of hypertrophic growth in engineered heart tissue.
Circulation research 2011;109(10):1105-14.
2011: Cornelia Grebe; Theda-Maria Klingebiel; Simon Philipp Grau; Karl Toischer; Michael Didié; Claudius Jacobshagen; Christian Dullin; Gerd Hasenfuss; Tim Seidler
Enhanced expression of DYRK1A in cardiomyocytes inhibits acute NFAT activation but does not prevent hypertrophy in vivo.
Cardiovascular research 2011;90(3):521-8.
2011: Samuel Sossalla; Ulrike Maurer; Hanna Schotola; Nico Hartmann; Michael Didié; Wolfram-Hubertus Zimmermann; Claudius Jacobshagen; Stefan Wagner; Lars S Maier
Diastolic dysfunction and arrhythmias caused by overexpression of CaMKIIδ(C) can be reversed by inhibition of late Na(+) current.
Basic research in cardiology 2011;106(2):263-72.
2010: Marius Vantler; Bijoy Chandapillai Karikkineth; Hiroshi Naito; Malte Tiburcy; Michael Didié; Monika Nose; Stephan Rosenkranz; Wolfram-Hubertus Zimmermann
PDGF-BB protects cardiomyocytes from apoptosis and improves contractile function of engineered heart tissue.
Journal of molecular and cellular cardiology 2010;48(6):1316-23.
2010: Volker Rudolph; René P Andrié; Tanja K Rudolph; Kai Friedrichs; Anna Klinke; Birgit Hirsch-Hoffmann; Alexander P Schwoerer; Denise Lau; Xiaoming Fu; Karin Klingel; Karsten Sydow; Michael Didié; Anika Seniuk; Eike-Christin von Leitner; Katalin Szoecs; Jan W Schrickel; Hendrik Treede; Ulrich Wenzel; Thorsten Lewalter; Georg Nickenig; Wolfram-Hubertus Zimmermann; Thomas Meinertz; Rainer H Böger; Hermann Reichenspurner; Bruce A Freeman; Thomas Eschenhagen; Heimo Ehmke; Stanley L Hazen; Stephan Willems; Stephan Baldus
Myeloperoxidase acts as a profibrotic mediator of atrial fibrillation.
Nature medicine 2010;16(4):470-4.
2010: Ralph Knöll; Sawa Kostin; Stefanie Klede; Kostas Savvatis; Lars Klinge; Ina Stehle; Sylvia Gunkel; Sebastian Kötter; Kamila Babicz; Melanie Sohns; Snjezana Miocic; Michael Didié; Gudrun Knöll; Wolfram-Hubertus Zimmermann; Paul Thelen; Heike Bickeböller; Lars S Maier; Wolfgang Schaper; Jutta Schaper; Theresia Kraft; Carsten Tschöpe; Wolfgang A Linke; Kenneth R Chien
A common MLP (muscle LIM protein) variant is associated with cardiomyopathy.
Circulation research 2010;106(4):695-704.
2008: Ali El-Armouche; Katrin Wittköpper; Franziska Degenhardt; Florian Weinberger; Michael Didié; Ivan Melnychenko; Michael Grimm; Micha Peeck; Wolfram-Hubertus Zimmermann; Bernhard Unsöld; Gerd Hasenfuss; Dobromir Dobrev; Thomas Eschenhagen
Phosphatase inhibitor-1-deficient mice are protected from catecholamine-induced arrhythmias and myocardial hypertrophy.
Cardiovascular research 2008;80(3):396-406.
2008: Ralf A Benndorf; Edzard Schwedhelm; Anke Gnann; Raihana Taheri; Ghainsom Kom; Michael Didié; Anna Steenpass; Süleyman Ergün; Rainer H Böger
Isoprostanes inhibit vascular endothelial growth factor-induced endothelial cell migration, tube formation, and cardiac vessel sprouting in vitro, as well as angiogenesis in vivo via activation of the thromboxane A(2) receptor: a potential link between oxidative stress and impaired angiogenesis.
Circulation research 2008;103(9):1037-46.
2007: Yalin Yildirim; Hiroshi Naito; Michael Didié; Bijoy Chandapillai Karikkineth; Daniel Biermann; Thomas Eschenhagen; Wolfram-Hubertus Zimmermann
Development of a biological ventricular assist device: preliminary data from a small animal model.
Circulation 2007;116(11 Suppl):I16-23.
2007: Ali El-Armouche; Jasmin Singh; Hiroshi Naito; Katrin Wittköpper; Michael Didié; Alexander Laatsch; Wolfram-Hubertus Zimmermann; Thomas Eschenhagen
Adenovirus-delivered short hairpin RNA targeting PKCalpha improves contractile function in reconstituted heart tissue.
Journal of molecular and cellular cardiology 2007;43(3):371-6.
2006: Ali El-Armouche; Anna Bednorz; Torsten Pamminger; Diana Ditz; Michael Didié; Dobromir Dobrev; Thomas Eschenhagen
Role of calcineurin and protein phosphatase-2A in the regulation of phosphatase inhibitor-1 in cardiac myocytes.
Biochemical and biophysical research communications 2006;346(3):700-6.
2006: Wolfram-Hubertus Zimmermann; Michael Didié; Stephan Döker; Ivan Melnychenko; Hiroshi Naito; Christina Rogge; Malte Tiburcy; Thomas Eschenhagen
Heart muscle engineering: an update on cardiac muscle replacement therapy.
Cardiovascular research 2006;71(3):419-29.
2006: Hiroshi Naito; Ivan Melnychenko; Michael Didié; Karin Schneiderbanger; Peter Schubert; Stephan Rosenkranz; Thomas Eschenhagen; Wolfram-Hubertus Zimmermann
Optimizing engineered heart tissue for therapeutic applications as surrogate heart muscle.
Circulation 2006;114(1 Suppl):I72-8.
2006: Wolfram-Hubertus Zimmermann; Ivan Melnychenko; Gerald H Wasmeier; Michael Didié; Hiroshi Naito; Uwe Nixdorff; Andreas Hess; Lubos Budinsky; Kay Brune; Bjela Michaelis; Stefan Dhein; Alexander Peter Schwoerer; Heimo Ehmke; Thomas Eschenhagen
Engineered heart tissue grafts improve systolic and diastolic function in infarcted rat hearts.
Nature medicine 2006;12(4):452-8.
2006: Marco B Rust; Jörg Faulhaber; Mareike K Budack; Carsten Pfeffer; Tanja Maritzen; Michael Didié; Franz-Xaver Beck; Thomas Boettger; Rudolf Schubert; Heimo Ehmke; Thomas J Jentsch; Christian A Hübner
Neurogenic mechanisms contribute to hypertension in mice with disruption of the K-Cl cotransporter KCC3.
Circulation research 2006;98(4):549-56.
2005: Felix Münzel; Ulrike Mühlhäuser; Wolfram-Hubertus Zimmermann; Michael Didié; Karin Schneiderbanger; Peter Schubert; Sven Engmann; Thomas Eschenhagen; Oliver Zolk
Endothelin-1 and isoprenaline co-stimulation causes contractile failure which is partially reversed by MEK inhibition.
Cardiovascular research 2005;68(3):464-74.
2002: Wolfram-Hubertus Zimmermann; Michael Didié; Gerald H Wasmeier; Uwe Nixdorff; Andreas Hess; Ivan Melnychenko; Oliver Boy; Winfried Neuhuber; Michael Weyand; Thomas Eschenhagen
Cardiac grafting of engineered heart tissue in syngenic rats.
Circulation 2002;106(12 Suppl 1):I151-7.
2002: Thomas Eschenhagen; Michael Didié; Jürgen Heubach; Ursula Ravens; Wolfram-Hubertus Zimmermann
Cardiac tissue engineering.
Transplant immunology 2002;9(2-4):315-21.
2002: Wolfram-Hubertus Zimmermann; Karin Schneiderbanger; Peter Schubert; Michael Didié; Felix Münzel; Jürgen Heubach; S Kostin; Winfried Neuhuber; Thomas Eschenhagen
Tissue engineering of a differentiated cardiac muscle construct.
Circulation research 2002;90(2):223-30.
2002: Thomas Eschenhagen; Michael Didié; Felix Münzel; Peter Schubert; Karin Schneiderbanger; Wolfram-Hubertus Zimmermann
3D engineered heart tissue for replacement therapy.
Basic research in cardiology 2002;97 Suppl 1():I146-52.