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Robert Diegelmann

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Rebecca A Segal; Kevin R Ward; Robert F Diegelmann; Angela Reynolds
A differential equation model of collagen accumulation in a healing wound.
Stephanie R Goldberg; Robert F Diegelmann
Wound healing primer.
Stephanie R Goldberg; Robert F Diegelmann
Wound healing primer.

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All Publications

2012: Rebecca A Segal; Kevin R Ward; Robert F Diegelmann; Angela Reynolds
A differential equation model of collagen accumulation in a healing wound.
Bulletin of mathematical biology 2012;74(9):2165-82.
2012: Stephanie R Goldberg; Robert F Diegelmann
Wound healing primer.
Critical care nursing clinics of North America 2012;24(2):165-78.
2010: Stephanie R Goldberg; Robert F Diegelmann
Wound healing primer.
The Surgical clinics of North America 2010;90(6):1133-46.
2010: Nathan J White; Erika J Martin; Yongyun Shin; Donald F Brophy; Robert F Diegelmann; Kevin R Ward
Systemic central venous oxygen saturation is associated with clot strength during traumatic hemorrhagic shock: A preclinical observational model.
Scandinavian journal of trauma, resuscitation and emergency medicine 2010;18():64.
2010: Nathan B Menke; John W Cain; Angela Reynolds; David M Chan; Rebecca A Segal; Tarynn M Witten; Danail G Bonchev; Robert F Diegelmann; Kevin R Ward
An in silico approach to the analysis of acute wound healing.
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 2010;18(1):105-13.
2009: V Ramana Feeser; Nathan B Menke; Kevin R Ward; Roger M Loria; Robert F Diegelmann
Androstenediol reverses steroid-inhibited wound healing.
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 2009;17(5):758-61.
2008: Marie Menke; Nathan B Menke; Cecelia H Boardman; Robert F Diegelmann
Biologic therapeutics and molecular profiling to optimize wound healing.
Gynecologic oncology 2008;111(2 Suppl):S87-91.
2008: Harold Brem; Michael S Golinko; Olivera Stojadinovic; Arber Kodra; Robert F Diegelmann; Sasa Vukelic; Hyacinth Entero; Donald L Coppock; Marjana Tomic
Primary cultured fibroblasts derived from patients with chronic wounds: a methodology to produce human cell lines and test putative growth factor therapy such as GMCSF.
Journal of translational medicine 2008;6():75.
2007: Andreea C Marcu; Kristin E Paccione; R Wayne Barbee; Robert F Diegelmann; Rao R Ivatury; Kevin R Ward; Roger M Loria
Androstenetriol immunomodulation improves survival in a severe trauma hemorrhage shock model.
The Journal of trauma 2007;63(3):662-9.
2007: Kenneth R Watterson; David A Lanning; Robert F Diegelmann; Sarah Spiegel
Regulation of fibroblast functions by lysophospholipid mediators: potential roles in wound healing.
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 2007;15(5):607-16.
2007: Kevin R Ward; M Hakam Tiba; William H Holbert; Charles R Blocher; Gerard T Draucker; E Kate Proffitt; Gary Bowlin; Rao R Ivatury; Robert F Diegelmann
Comparison of a new hemostatic agent to current combat hemostatic agents in a Swine model of lethal extremity arterial hemorrhage.
The Journal of trauma 2007;63(2):276-83; discussion 283-4.
2007: Melissa C Evans; Robert F Diegelmann; R Wayne Barbee; M Hakam Tiba; Eric Edwards; Sue Sreedhar; Kevin R Ward
Protein synthesis inhibition as a potential strategy for metabolic down-regulation.
Resuscitation 2007;73(2):296-303.
2007: Harold Brem; Olivera Stojadinovic; Robert F Diegelmann; Hyacinth Entero; Brian Lee; Irena Pastar; Michael Golinko; Harvey Rosenberg; Marjana Tomic
Molecular markers in patients with chronic wounds to guide surgical debridement.
Molecular medicine (Cambridge, Mass.) 2007;13(1-2):30-9.
2007: Nathan B Menke; Kevin R Ward; Tarynn M Witten; Danail Bonchev; Robert F Diegelmann
Impaired wound healing.
Clinics in dermatology 2007;25(1):19-25.
2006: Andreea C Marcu; Nicole D Kielar; Kristin E Paccione; R Wayne Barbee; Hans Carter; Rao R Ivatury; Robert F Diegelmann; Kevin R Ward; Roger M Loria
Androstenetriol improves survival in a rodent model of traumatic shock.
Resuscitation 2006;71(3):379-86.
2004: Robert F Diegelmann; Melissa C Evans
Wound healing: an overview of acute, fibrotic and delayed healing.
Frontiers in bioscience : a journal and virtual library 2004;9():283-9.
2003: Robert F Diegelmann
Excessive neutrophils characterize chronic pressure ulcers.
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 2003;11(6):490-5.
2003: Robert F Diegelmann
Analysis of collagen synthesis.
Methods in molecular medicine 2003;78():349-58.
2002: I Kelman Cohen; Robert F Diegelmann
How the Wound Healing Society began.
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 2002;10(3):195-7.
2001: Ramesh Natarajan; Shobha Ghosh; Bernard J Fisher; Robert F Diegelmann; Amy Willey; S Walsh; Martin F Graham; Alpha A Fowler
Redox imbalance in Crohn's disease intestinal smooth muscle cells causes NF-kappaB-mediated spontaneous interleukin-8 secretion.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2001;21(6):349-59.
2001: J Vincent Edwards; Dorne R Yager; I Kelman Cohen; Robert F Diegelmann; SJ Montante; N Bertoniere; Alvin F Bopp
Modified cotton gauze dressings that selectively absorb neutrophil elastase activity in solution.
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 2001;9(1):50-8.
2000: C I Kennedy; Robert F Diegelmann; Jeffrey H Haynes; Dorne R Yager
Proinflammatory cytokines differentially regulate hyaluronan synthase isoforms in fetal and adult fibroblasts.
Journal of pediatric surgery 2000;35(6):874-9.
2000: David A Lanning; Robert F Diegelmann; Dorne R Yager; Michael L Wallace; Charles E Bagwell; Jeffrey H Haynes
Myofibroblast induction with transforming growth factor-beta1 and -beta3 in cutaneous fetal excisional wounds.
Journal of pediatric surgery 2000;35(2):183-7; discussion 187-8.
1999: G Rosenblat; Amy Willey; YN Zhu; A Jonas; Robert F Diegelmann; Ishak Neeman; Martin F Graham
Palmitoyl ascorbate: selective augmentation of procollagen mRNA expression compared with L-ascorbate in human intestinal smooth muscle cells.
Journal of cellular biochemistry 1999;73(3):312-20.
1999: David A Lanning; BC Nwomeh; SJ Montante; Dorne R Yager; Robert F Diegelmann; Jeffrey H Haynes
TGF-beta1 alters the healing of cutaneous fetal excisional wounds.
Journal of pediatric surgery 1999;34(5):695-700.
1999: J Vincent Edwards; Alvin F Bopp; Sarah L Batiste; A J Ullah; I Kelman Cohen; Robert F Diegelmann; SJ Montante
Inhibition of elastase by a synthetic cotton-bound serine protease inhibitor: in vitro kinetics and inhibitor release.
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 1999;7(2):106-18.
1999: L J Gould; Dorne R Yager; G M McGeehan; Robert F Diegelmann
Method to analyze collagenase and gelatinase activity by fibroblasts in culture.
In vitro cellular & developmental biology. Animal 1999;35(2):75-9.
1998: EJ Barone; Dorne R Yager; Andrea L Pozez; OO Olutoye; M C Crossland; Robert F Diegelmann; I Kelman Cohen
Interleukin-1alpha and collagenase activity are elevated in chronic wounds.
Plastic and reconstructive surgery 1998;102(4):1023-7; discussion 1028-9.
1998: BC Nwomeh; H X Liang; Robert F Diegelmann; I Kelman Cohen; Dorne R Yager
Dynamics of the matrix metalloproteinases MMP-1 and MMP-8 in acute open human dermal wounds.
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 1998;6(2):127-34.
1997: Martin F Graham; Amy Willey; YN Zhu; Dorne R Yager; H J Sugerman; Robert F Diegelmann
Corticosteroids repress the interleukin 1 beta-induced secretion of collagenase in human intestinal smooth muscle cells.
Gastroenterology 1997;113(6):1924-9.
1997: B A Mast; Jeffrey H Haynes; T M Krummel; I Kelman Cohen; Robert F Diegelmann
Ultrastructural analysis of fetal rabbit wounds.
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 1997;5(3):243-8.
1997: OO Olutoye; EJ Barone; Dorne R Yager; T Uchida; I Kelman Cohen; Robert F Diegelmann
Hyaluronic acid inhibits fetal platelet function: implications in scarless healing.
Journal of pediatric surgery 1997;32(7):1037-40.
1997: OO Olutoye; EJ Barone; Dorne R Yager; I Kelman Cohen; Robert F Diegelmann
Collagen induces cytokine release by fetal platelets: implications in scarless healing.
Journal of pediatric surgery 1997;32(6):827-30.
1997: M W Kofford; Lawrence B Schwartz; N M Schechter; Dorne R Yager; Robert F Diegelmann; Martin F Graham
Cleavage of type I procollagen by human mast cell chymase initiates collagen fibril formation and generates a unique carboxyl-terminal propeptide.
The Journal of biological chemistry 1997;272(11):7127-31.
1997: S M Chen; Susan I Ward; OO Olutoye; Robert F Diegelmann; I Kelman Cohen
Ability of chronic wound fluids to degrade peptide growth factors is associated with increased levels of elastase activity and diminished levels of proteinase inhibitors.
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 1997;5(1):23-32.
1997: Robert F Diegelmann
Cellular and biochemical aspects of normal and abnormal wound healing: an overview.
The Journal of urology 1997;157(1):298-302.
1996: Dorne R Yager; L Y Zhang; H X Liang; Robert F Diegelmann; I Kelman Cohen
Wound fluids from human pressure ulcers contain elevated matrix metalloproteinase levels and activity compared to surgical wound fluids.
The Journal of investigative dermatology 1996;107(5):743-8.
1996: Samuel M. Alaish; OO Olutoye; Dorne R Yager; H X Liang; I Kelman Cohen; Robert F Diegelmann
Transforming growth factor-beta1 reduces expansion of open wounds in the fetal rabbit.
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 1996;4(4):477-81.
1996: D A Bettinger; Dorne R Yager; Robert F Diegelmann; I Kelman Cohen
The effect of TGF-beta on keloid fibroblast proliferation and collagen synthesis.
Plastic and reconstructive surgery 1996;98(5):827-33.
1996: Martin F Graham; Amy Willey; J Adams; Dorne R Yager; Robert F Diegelmann
Interleukin 1 beta down-regulates collagen and augments collagenase expression in human intestinal smooth muscle cells.
Gastroenterology 1996;110(2):344-50.
1996: Robert F Diegelmann; J D Dunn; W J Lindblad; I Kelman Cohen
Analysis of the effects of chitosan on inflammation, angiogenesis, fibroplasia, and collagen deposition in polyvinyl alcohol sponge implants in rat wounds.
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 1996;4(1):48-52.
1996: OO Olutoye; Dorne R Yager; I Kelman Cohen; Robert F Diegelmann
Lower cytokine release by fetal porcine platelets: a possible explanation for reduced inflammation after fetal wounding.
Journal of pediatric surgery 1996;31(1):91-5.
1995: OO Olutoye; Samuel M. Alaish; M E Carr; M Paik; Dorne R Yager; I Kelman Cohen; Robert F Diegelmann
Aggregatory characteristics and expression of the collagen adhesion receptor in fetal porcine platelets.
Journal of pediatric surgery 1995;30(12):1649-53.
1995: Martin F Graham; Amy Willey; J Adams; Robert F Diegelmann
Corticosteroids increase procollagen gene expression, synthesis, and secretion by human intestinal smooth muscle cells.
Gastroenterology 1995;109(5):1454-61.
1995: Jeffrey H Haynes; Bruce A Mast; T M Krummel; I Kelman Cohen; Robert F Diegelmann
Exposure to amniotic fluid inhibits closure of open wounds in the fetal rabbit.
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 1995;3(4):467-72.
1995: I Kelman Cohen; M C Crossland; A Garrett; Robert F Diegelmann
Topical application of epidermal growth factor onto partial-thickness wounds in human volunteers does not enhance reepithelialization.
Plastic and reconstructive surgery 1995;96(2):251-4.
1995: Samuel M. Alaish; D A Bettinger; OO Olutoye; L J Gould; Dorne R Yager; A Davis; M C Crossland; Robert F Diegelmann; I Kelman Cohen
Comparison of the polyvinyl alcohol sponge and expanded polytetrafluoroethylene subcutaneous implants as models to evaluate wound healing potential in human beings.
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 1995;3(3):292-8.
1995: Samuel M. Alaish; Dorne R Yager; Robert F Diegelmann; I Kelman Cohen
Hyaluronic acid metabolism in keloid fibroblasts.
Journal of pediatric surgery 1995;30(7):949-52.
1995: Martin F Graham; Amy Willey; J Adams; Dorne R Yager; Robert F Diegelmann
Role of ascorbic acid in procollagen expression and secretion by human intestinal smooth muscle cells.
Journal of cellular physiology 1995;162(2):225-33.
1995: Bruce A Mast; F W Frantz; Robert F Diegelmann; T M Krummel; I Kelman Cohen
Hyaluronic acid degradation products induce neovascularization and fibroplasia in fetal rabbit wounds.
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 1995;3(1):66-72.
1994: Jeffrey H Haynes; D E Johnson; Bruce A Mast; Robert F Diegelmann; D A Salzberg; I Kelman Cohen; T M Krummel
Platelet-derived growth factor induces fetal wound fibrosis.
Journal of pediatric surgery 1994;29(11):1405-8.
1994: Samuel M. Alaish; Dorne R Yager; Robert F Diegelmann; I Kelman Cohen
Biology of fetal wound healing: hyaluronate receptor expression in fetal fibroblasts.
Journal of pediatric surgery 1994;29(8):1040-3.
1994: D A Bettinger; J V Pellicane; W C Tarry; Dorne R Yager; Robert F Diegelmann; R Lee; I Kelman Cohen; Eric J DeMaria
The role of inflammatory cytokines in wound healing: accelerated healing in endotoxin-resistant mice.
The Journal of trauma 1994;36(6):810-3; discussion 813-4.
1993: Bruce A Mast; Robert F Diegelmann; T M Krummel; I Kelman Cohen
Hyaluronic acid modulates proliferation, collagen and protein synthesis of cultured fetal fibroblasts.
Matrix (Stuttgart, Germany) 1993;13(6):441-6.
1993: F W Frantz; D A Bettinger; Jeffrey H Haynes; D E Johnson; K M Harvey; H P Dalton; Dorne R Yager; Robert F Diegelmann; I Kelman Cohen
Biology of fetal repair: the presence of bacteria in fetal wounds induces an adult-like healing response.
Journal of pediatric surgery 1993;28(3):428-33; discussion 433-4.
1992: F W Frantz; Robert F Diegelmann; Bruce A Mast; I Kelman Cohen
Biology of fetal wound healing: collagen biosynthesis during dermal repair.
Journal of pediatric surgery 1992;27(8):945-8; discussion 949.
1992: Bruce A Mast; Robert F Diegelmann; T M Krummel; I Kelman Cohen
Scarless wound healing in the mammalian fetus.
Surgery, gynecology & obstetrics 1992;174(5):441-51.
1992: Bruce A Mast; Jeffrey H Haynes; T M Krummel; Robert F Diegelmann; I Kelman Cohen
In vivo degradation of fetal wound hyaluronic acid results in increased fibroplasia, collagen deposition, and neovascularization.
Plastic and reconstructive surgery 1992;89(3):503-9.
1992: H A Perr; J R Grider; A S Mills; M Kornstein; D A Turner; Robert F Diegelmann; Martin F Graham
Collagen production by human smooth muscle cells isolated during intestinal organogenesis.
Anatomy and embryology 1992;185(6):517-27.
1991: Bruce A Mast; L C Flood; Jeffrey H Haynes; R L DePalma; I Kelman Cohen; Robert F Diegelmann; T M Krummel
Hyaluronic acid is a major component of the matrix of fetal rabbit skin and wounds: implications for healing by regeneration.
Matrix (Stuttgart, Germany) 1991;11(1):63-8.
1991: T M Krummel; Bruce A Mast; Jeffrey H Haynes; Robert F Diegelmann; I Kelman Cohen
Characteristics of fetal repair.
Progress in clinical and biological research 1991;365():167-76.
1991: B H Rice; Jeffrey H Haynes; B L Thomas; L C Flood; I Kelman Cohen; Robert F Diegelmann; T M Krummel
Analysis of skin grafting techniques in the fetal rabbit.
Journal of investigative surgery : the official journal of the Academy of Surgical Research 1991;4(1):69-73.
1990: Martin F Graham; G R Bryson; Robert F Diegelmann
Transforming growth factor beta 1 selectively augments collagen synthesis by human intestinal smooth muscle cells.
Gastroenterology 1990;99(2):447-53.
1990: Robert F Diegelmann; G R Bryson; L C Flood; Martin F Graham
A microassay to quantitate collagen synthesis by cells in culture.
Analytical biochemistry 1990;186(2):296-300.
1990: Jeffrey H Haynes; T M Krummel; L C Flood; I Kelman Cohen; Robert F Diegelmann
Fetal skin organ culture.
Journal of investigative surgery : the official journal of the Academy of Surgical Research 1990;3(4):349-55.
1989: H A Perr; D E Drucker; David L Cochran; Robert F Diegelmann; W J Lindblad; Martin F Graham
Protamine selectively inhibits collagen synthesis by human intestinal smooth muscle cells and other mesenchymal cells.
Journal of cellular physiology 1989;140(3):463-70.
1989: L A Durham; T M Krummel; J W Cawthorn; B L Thomas; Robert F Diegelmann
Analysis of transforming growth factor beta receptor binding in embryonic, fetal, and adult rabbit fibroblasts.
Journal of pediatric surgery 1989;24(8):784-8.
1989: R L DePalma; T M Krummel; L A Durham; B A Michna; B L Thomas; J M Nelson; Robert F Diegelmann
Characterization and quantitation of wound matrix in the fetal rabbit.
Matrix (Stuttgart, Germany) 1989;9(3):224-31.
1989: H A Perr; Martin F Graham; Robert F Diegelmann; Robert Downs
Cyclic nucleotides regulate collagen production by human intestinal smooth muscle cells.
Gastroenterology 1989;96(6):1521-8.
1989: Robert F Diegelmann; W J Lindblad; R W Hussey; Susan J Maygarden; I Kelman Cohen
Analysis of fibrogenic processes in denervated tissues of spinal cord injury patients.
Plastic and reconstructive surgery 1989;83(2):309-14.
1988: J M Nelson; Robert F Diegelmann; I Kelman Cohen
Effect of beta-aminopropionitrile and ascorbate on fibroblast migration.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 1988;188(3):346-52.
1988: T M Krummel; B A Michna; B L Thomas; Michael B. Sporn; J M Nelson; A M Salzberg; I Kelman Cohen; Robert F Diegelmann
Transforming growth factor beta (TGF-beta) induces fibrosis in a fetal wound model.
Journal of pediatric surgery 1988;23(7):647-52.
1988: Martin F Graham; Robert F Diegelmann; C O Elson; W J Lindblad; N Gotschalk; S Gay; R Gay
Collagen content and types in the intestinal strictures of Crohn's disease.
Gastroenterology 1988;94(2):257-65.
1987: Robert F Diegelmann; J C Kim; W J Lindblad; T C Smith; T M Harris; I Kelman Cohen
Collection of leukocytes, fibroblasts, and collagen within an implantable reservoir tube during tissue repair.
Journal of leukocyte biology 1987;42(6):667-72.
1987: Martin F Graham; D E Drucker; H A Perr; Robert F Diegelmann; H P Ehrlich
Heparin modulates human intestinal smooth muscle cell proliferation, protein synthesis, and lattice contraction.
Gastroenterology 1987;93(4):801-9.
1987: T M Krummel; J M Nelson; Robert F Diegelmann; W J Lindblad; A M Salzberg; Lazar J Greenfield; I Kelman Cohen
Fetal response to injury in the rabbit.
Journal of pediatric surgery 1987;22(7):640-4.
1987: Martin F Graham; D E Drucker; Robert F Diegelmann; C O Elson
Collagen synthesis by human intestinal smooth muscle cells in culture.
Gastroenterology 1987;92(2):400-5.
1986: Robert F Diegelmann; W J Lindblad; I Kelman Cohen
A subcutaneous implant for wound healing studies in humans.
The Journal of surgical research 1986;40(3):229-37.
1984: W J Lindblad; Robert F Diegelmann
Chromatographic separation of preparative quantities of the stereoisomers of trans-2,3-cis-3,4-dihydroxy-L-proline.
Journal of chromatography 1984;315():447-50.
1984: Martin F Graham; Robert F Diegelmann; C O Elson; Khalil N Bitar; H P Ehrlich
Isolation and culture of human intestinal smooth muscle cells.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 1984;176(4):503-7.
1984: Martin F Graham; Robert F Diegelmann; I K Cohen
An in vitro model of fibroplasia: simultaneous quantification of fibroblast proliferation, migration, and collagen synthesis.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 1984;176(3):302-8.
1984: W J Lindblad; Robert F Diegelmann
Quantitation of hydroxyproline isomers in acid hydrolysates by high-performance liquid chromatography.
Analytical biochemistry 1984;138(2):390-5.
1984: P S Guzelian; W J Lindblad; Robert F Diegelmann
Glucocorticoids suppress formation of collagen by the hepatocyte. Studies in primary monolayer cultures of parenchymal cells prepared from adult rat liver.
Gastroenterology 1984;86(5 Pt 1):897-904.
1984: Martin F Graham; H Becker; I K Cohen; W Merritt; Robert F Diegelmann
Intrinsic tendon fibroplasia: documentation by in vitro studies.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 1984;1(3):251-6.