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Bruce Ames
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26
Gold, Lois Swirsky
25
Shigenaga, Mark
13
Atamna, Hani
11
Hagen, Tory
10
Wehr, Carol
9
Slone, Thomas
8
Storz, Gisela
8
Killilea, David
8
Manley, Neela
8
Christen, Stephan
7
Jiang, Qing
7
Liu, Jiankang
6
Lykkesfeldt, Jens
6
Mashiyama, Susan
6
Walter, Patrick
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All Publications
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2009: McCann Joyce C; Ames Bruce N
Vitamin K, an example of triage theory: is micronutrient inadequacy linked to diseases of aging?
The American journal of clinical nutrition 2009;90(4):889-907.
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2009: Suh Jung H; Kim Robert; Yavuz Burcu; Lee Daniel; Lal Ashutosh; Ames Bruce N; Shigenaga Mark K
Clinical assay of four thiol amino acid redox couples by LC-MS/MS: utility in thalassemia.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2009;877(28):3418-27.
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2009: Hudes Mark L; McCann Joyce C; Ames Bruce N
Unusual clustering of coefficients of variation in published articles from a medical biochemistry department in India.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2009;23(3):689-703.
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2008: King Sarah M; Donangelo Carmen M; Knutson Mitchell D; Walter Patrick B; Ames Bruce N; Viteri Fernando E; King Janet C
Daily supplementation with iron increases lipid peroxidation in young women with low iron stores.
Experimental biology and medicine (Maywood, N.J.) 2008;233(6):701-7.
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2008: Killilea David W; Ames Bruce N
Magnesium deficiency accelerates cellular senescence in cultured human fibroblasts.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(15):5768-73.
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2008: McCann Joyce C; Ames Bruce N
Is there convincing biological or behavioral evidence linking vitamin D deficiency to brain dysfunction?
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2008;22(4):982-1001.
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2008: Atamna Hani; Nguyen Andy; Schultz Carla; Boyle Kathleen; Newberry Justin; Kato Hiroyuki; Ames Bruce N
Methylene blue delays cellular senescence and enhances key mitochondrial biochemical pathways.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2008;22(3):703-12.
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2008: Mashiyama Susan T; Hansen Christine M; Roitman Esther; Sarmiento Stella; Leklem James E; Shultz Terry D; Ames Bruce N
An assay for uracil in human DNA at baseline: effect of marginal vitamin B6 deficiency.
Analytical biochemistry 2008;372(1):21-31.
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2008: Lal Ashutosh; Atamna Wafa; Killilea David W; Suh Jung H; Ames Bruce N
Lipoic acid and acetyl-carnitine reverse iron-induced oxidative stress in human fibroblasts.
Redox report : communications in free radical research 2008;13(1):2-10.
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2007: Voloboueva Ludmila A; Killilea David W; Atamna Hani; Ames Bruce N
N-tert-butyl hydroxylamine, a mitochondrial antioxidant, protects human retinal pigment epithelial cells from iron overload: relevance to macular degeneration.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2007;21(14):4077-86.
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2007: Ames Bruce N; McCann Joyce C; Stampfer Meir J; Willett Walter C
Evidence-based decision making on micronutrients and chronic disease: long-term randomized controlled trials are not enough.
The American journal of clinical nutrition 2007;86(2):522-3; author reply 523-4.
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2007: Offer Tal; Ames Bruce N; Bailey Steven W; Sabens Elizabeth A; Nozawa Mamoru; Ayling June E
5-Methyltetrahydrofolate inhibits photosensitization reactions and strand breaks in DNA.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2007;21(9):2101-7.
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2007: McCann Joyce C; Ames Bruce N
An overview of evidence for a causal relation between iron deficiency during development and deficits in cognitive or behavioral function.
The American journal of clinical nutrition 2007;85(4):931-45.
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2007: Wallock-Montelius Lynn M; Villanueva Jesus A; Chapin Robert E; Conley A J; Nguyen Hung P; Ames Bruce N; Halsted Charles H
Chronic ethanol perturbs testicular folate metabolism and dietary folate deficiency reduces sex hormone levels in the Yucatan micropig.
Biology of reproduction 2007;76(3):455-65.
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2007: Jia Lihong; Liu Zhongbo; Sun Lijuan; Miller Sheldon S; Ames Bruce N; Cotman Carl W; Liu Jiankang
Acrolein, a toxicant in cigarette smoke, causes oxidative damage and mitochondrial dysfunction in RPE cells: protection by (R)-alpha-lipoic acid.
Investigative ophthalmology & visual science 2007;48(1):339-48.
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2007: Atamna Hani; Newberry Justin; Erlitzki Ronit; Schultz Carla S; Ames Bruce N
Biotin deficiency inhibits heme synthesis and impairs mitochondria in human lung fibroblasts.
The Journal of nutrition 2007;137(1):25-30.
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2006: Ames Bruce N
Low micronutrient intake may accelerate the degenerative diseases of aging through allocation of scarce micronutrients by triage.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(47):17589-94.
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2006: McCann Joyce C; Hudes Mark; Ames Bruce N
An overview of evidence for a causal relationship between dietary availability of choline during development and cognitive function in offspring.
Neuroscience and biobehavioral reviews 2006;30(5):696-712.
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2005: Voloboueva Ludmila A; Liu Jiankang; Suh Jung H; Ames Bruce N; Miller Sheldon S
(R)-alpha-lipoic acid protects retinal pigment epithelial cells from oxidative damage.
Investigative ophthalmology & visual science 2005;46(11):4302-10.
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2005: Ames Bruce N; Atamna Hani; Killilea David W
Mineral and vitamin deficiencies can accelerate the mitochondrial decay of aging.
Molecular aspects of medicine 2005;26(4-5):363-78.
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2005: McCann Joyce C; Ames Bruce N
Is docosahexaenoic acid, an n-3 long-chain polyunsaturated fatty acid, required for development of normal brain function? An overview of evidence from cognitive and behavioral tests in humans and animals.
The American journal of clinical nutrition 2005;82(2):281-95.
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2005: Kadiiska M B; Gladen B C; Baird D D; Graham L B; Parker C E; Ames B N; Basu S; Fitzgerald G A; Lawson J A; Marnett L J; Morrow J D; Murray D M; Plastaras J; Roberts L J; Rokach J; Shigenaga M K; Sun J; Walter P B; Tomer K B; Barrett J C; Mason R P
Biomarkers of oxidative stress study III. Effects of the nonsteroidal anti-inflammatory agents indomethacin and meclofenamic acid on measurements of oxidative products of lipids in CCl4 poisoning.
Free radical biology & medicine 2005;38(6):711-8.
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2005: Offer Tal; Ho Emily; Traber Maret G; Bruno Richard S; Kuypers Frans A; Ames Bruce N
A simple assay for frequency of chromosome breaks and loss (micronuclei) by flow cytometry of human reticulocytes.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(3):485-7.
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2005: Offer Tal; Bhagat Amrita; Lal Ashutosh; Atamna Wafa; Singer Sylvia T; Vichinsky Elliott P; Kuypers Frans A; Ames Bruce N
Measuring chromosome breaks in patients with thalassemia.
Annals of the New York Academy of Sciences 2005;1054():439-44.
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2004: Jiang Qing; Wong Jeffrey; Fyrst Henrik; Saba Julie D; Ames Bruce N
gamma-Tocopherol or combinations of vitamin E forms induce cell death in human prostate cancer cells by interrupting sphingolipid synthesis.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(51):17825-30.
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2004: Liu Jiankang; Head Elizabeth; Kuratsune Hirohiko; Cotman Carl W; Ames Bruce N
Comparison of the effects of L-carnitine and acetyl-L-carnitine on carnitine levels, ambulatory activity, and oxidative stress biomarkers in the brain of old rats.
Annals of the New York Academy of Sciences 2004;1033():117-31.
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2004: Ames Bruce N; Liu Jiankang
Delaying the mitochondrial decay of aging with acetylcarnitine.
Annals of the New York Academy of Sciences 2004;1033():108-16.
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2004: Ames Bruce N
Supplements and tuning up metabolism.
The Journal of nutrition 2004;134(11):3164S-3168S.
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2004: Courtemanche Chantal; Elson-Schwab Ilan; Mashiyama Susan T; Kerry Nicole; Ames Bruce N
Folate deficiency inhibits the proliferation of primary human CD8+ T lymphocytes in vitro.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(5):3186-92.
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2004: Mashiyama Susan T; Courtemanche Chantal; Elson-Schwab Ilan; Crott Jimmy; Lee Bee Lan; Ong Choon Nam; Fenech Michael; Ames Bruce N
Uracil in DNA, determined by an improved assay, is increased when deoxynucleosides are added to folate-deficient cultured human lymphocytes.
Analytical biochemistry 2004;330(1):58-69.
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2004: Ames Bruce N
Delaying the mitochondrial decay of aging.
Annals of the New York Academy of Sciences 2004;1019():406-11.
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2004: Killilea David W; Wong Stephanie L; Cahaya Hendry S; Atamna Hani; Ames Bruce N
Iron accumulation during cellular senescence.
Annals of the New York Academy of Sciences 2004;1019():365-7.
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2004: Ames Bruce N
Mitochondrial decay, a major cause of aging, can be delayed.
Journal of Alzheimer's disease : JAD 2004;6(2):117-21.
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2004: Ames Bruce N
A role for supplements in optimizing health: the metabolic tune-up.
Archives of biochemistry and biophysics 2004;423(1):227-34.
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2004: Courtemanche Chantal; Huang Arnold C; Elson-Schwab Ilan; Kerry Nicole; Ng Bernice Y; Ames Bruce N
Folate deficiency and ionizing radiation cause DNA breaks in primary human lymphocytes: a comparison.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2004;18(1):209-11.
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2003: Killilea David W; Atamna Hani; Liao Charles; Ames Bruce N
Iron accumulation during cellular senescence in human fibroblasts in vitro.
Antioxidants & redox signaling 2003;5(5):507-16.
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2003: Ho Emily; Courtemanche Chantal; Ames Bruce N
Zinc deficiency induces oxidative DNA damage and increases p53 expression in human lung fibroblasts.
The Journal of nutrition 2003;133(8):2543-8.
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2003: Jiang Qing; Blount Ben C; Ames Bruce N
5-Chlorouracil, a marker of DNA damage from hypochlorous acid during inflammation. A gas chromatography-mass spectrometry assay.
The Journal of biological chemistry 2003;278(35):32834-40.
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2003: Gogvadze Vladimir; Walter Patrick B; Ames Bruce N
The role of Fe2+-induced lipid peroxidation in the initiation of the mitochondrial permeability transition.
Archives of biochemistry and biophysics 2003;414(2):255-60.
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2003: Jiang Qing; Ames Bruce N
Gamma-tocopherol, but not alpha-tocopherol, decreases proinflammatory eicosanoids and inflammation damage in rats.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003;17(8):816-22.
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2003: Ames Bruce N
Delaying the mitochondrial decay of aging-a metabolic tune-up.
Alzheimer disease and associated disorders 2003;17 Suppl 2():S54-7.
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2003: Jacob Robert A; Aiello Giovanna M; Stephensen Charles B; Blumberg Jeffrey B; Milbury Paul E; Wallock Lynn M; Ames Bruce N
Moderate antioxidant supplementation has no effect on biomarkers of oxidant damage in healthy men with low fruit and vegetable intakes.
The Journal of nutrition 2003;133(3):740-3.
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2002: Ho Emily; Ames Bruce N
Low intracellular zinc induces oxidative DNA damage, disrupts p53, NFkappa B, and AP1 DNA binding, and affects DNA repair in a rat glioma cell line.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(26):16770-5.
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2002: Jiang Qing; Lykkesfeldt Jens; Shigenaga Mark K; Shigeno Eric T; Christen Stephan; Ames Bruce N
Gamma-tocopherol supplementation inhibits protein nitration and ascorbate oxidation in rats with inflammation.
Free radical biology & medicine 2002;33(11):1534-42.
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2002: Atamna Hani; Killilea David W; Killilea Alison Nisbet; Ames Bruce N
Heme deficiency may be a factor in the mitochondrial and neuronal decay of aging.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(23):14807-12.
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2002: Christen Stephan; Jiang Qing; Shigenaga Mark K; Ames Bruce N
Analysis of plasma tocopherols alpha, gamma, and 5-nitro-gamma in rats with inflammation by HPLC coulometric detection.
Journal of lipid research 2002;43(11):1978-85.
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2002: Liu Jiankang; Atamna Hani; Kuratsune Hirohiko; Ames Bruce N
Delaying brain mitochondrial decay and aging with mitochondrial antioxidants and metabolites.
Annals of the New York Academy of Sciences 2002;959():133-66.
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2002: Ames Bruce N; Elson-Schwab Ilan; Silver Eli A
High-dose vitamin therapy stimulates variant enzymes with decreased coenzyme binding affinity (increased K(m)): relevance to genetic disease and polymorphisms.
The American journal of clinical nutrition 2002;75(4):616-58.
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2002: Liu Jiankang; Head Elizabeth; Gharib Afshin M; Yuan Wenjun; Ingersoll Russell T; Hagen Tory M; Cotman Carl W; Ames Bruce N
Memory loss in old rats is associated with brain mitochondrial decay and RNA/DNA oxidation: partial reversal by feeding acetyl-L-carnitine and/or R-alpha -lipoic acid.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(4):2356-61.
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2002: Walter Patrick B; Knutson Mitchell D; Paler-Martinez Andres; Lee Sonia; Xu Yu; Viteri Fernando E; Ames Bruce N
Iron deficiency and iron excess damage mitochondria and mitochondrial DNA in rats.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(4):2264-9.
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2002: Liu Jiankang; Killilea David W; Ames Bruce N
Age-associated mitochondrial oxidative decay: improvement of carnitine acetyltransferase substrate-binding affinity and activity in brain by feeding old rats acetyl-L- carnitine and/or R-alpha -lipoic acid.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(4):1876-81.
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2002: Hagen Tory M; Liu Jiankang; Lykkesfeldt Jens; Wehr Carol M; Ingersoll Russell T; Vinarsky Vladimir; Bartholomew James C; Ames Bruce N
Feeding acetyl-L-carnitine and lipoic acid to old rats significantly improves metabolic function while decreasing oxidative stress.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(4):1870-5.
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2002: Gogvadze Vladimir; Walter Patrick B; Ames Bruce N
Fe(2+) induces a transient Ca(2+) release from rat liver mitochondria.
Archives of biochemistry and biophysics 2002;398(2):198-202.
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2002: Atamna Hani; Walter Patrick B; Ames Bruce N
The role of heme and iron-sulfur clusters in mitochondrial biogenesis, maintenance, and decay with age.
Archives of biochemistry and biophysics 2002;397(2):345-53.
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2001: Girault I; Karu A E; Schaper M; Barcellos-Hoff M H; Hagen T; Vogel D S; Ames B N; Christen S; Shigenaga M K
Immunodetection of 3-nitrotyrosine in the liver of zymosan-treated rats with a new monoclonal antibody: comparison to analysis by HPLC.
Free radical biology & medicine 2001;31(11):1375-87.
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2001: Jiang Q; Christen S; Shigenaga M K; Ames B N
gamma-tocopherol, the major form of vitamin E in the US diet, deserves more attention.
The American journal of clinical nutrition 2001;74(6):714-22.
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2001: Atamna H; Liu J; Ames B N
Heme deficiency selectively interrupts assembly of mitochondrial complex IV in human fibroblasts: revelance to aging.
The Journal of biological chemistry 2001;276(51):48410-6.
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2001: Atamna H; Robinson C; Ingersoll R; Elliott H; Ames B N
N-t-Butyl hydroxylamine is an antioxidant that reverses age-related changes in mitochondria in vivo and in vitro.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(12):2196-204.
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2001: Crott J W; Mashiyama S T; Ames B N; Fenech M
The effect of folic acid deficiency and MTHFR C677T polymorphism on chromosome damage in human lymphocytes in vitro.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2001;10(10):1089-96.
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2001: Crott J W; Mashiyama S T; Ames B N; Fenech M F
Methylenetetrahydrofolate reductase C677T polymorphism does not alter folic acid deficiency-induced uracil incorporation into primary human lymphocyte DNA in vitro.
Carcinogenesis 2001;22(7):1019-25.
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2001: Wallock L M; Tamura T; Mayr C A; Johnston K E; Ames B N; Jacob R A
Low seminal plasma folate concentrations are associated with low sperm density and count in male smokers and nonsmokers.
Fertility and sterility 2001;75(2):252-9.
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2000: Jiang Q; Elson-Schwab I; Courtemanche C; Ames B N
gamma-tocopherol and its major metabolite, in contrast to alpha-tocopherol, inhibit cyclooxygenase activity in macrophages and epithelial cells.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(21):11494-9.
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2000: Higdon J V; Liu J; Du S H; Morrow J D; Ames B N; Wander R C
Supplementation of postmenopausal women with fish oil rich in eicosapentaenoic acid and docosahexaenoic acid is not associated with greater in vivo lipid peroxidation compared with oils rich in oleate and linoleate as assessed by plasma malondialdehyde and F(2)-isoprostanes.
The American journal of clinical nutrition 2000;72(3):714-22.
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2000: Beckman K B; Saljoughi S; Mashiyama S T; Ames B N
A simpler, more robust method for the analysis of 8-oxoguanine in DNA.
Free radical biology & medicine 2000;29(3-4):357-67.
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2000: Liu J; Yeo H C; Overvik-Douki E; Hagen T; Doniger S J; Chyu D W; Brooks G A; Ames B N;
Chronically and acutely exercised rats: biomarkers of oxidative stress and endogenous antioxidants.
Journal of applied physiology (Bethesda, Md. : 1985) 2000;89(1):21-8.
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2000: Knutson M D; Walter P B; Ames B N; Viteri F E
Both iron deficiency and daily iron supplements increase lipid peroxidation in rats.
The Journal of nutrition 2000;130(3):621-8.
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2000: Atamna H; Paler-Martínez A; Ames B N
N-t-butyl hydroxylamine, a hydrolysis product of alpha-phenyl-N-t-butyl nitrone, is more potent in delaying senescence in human lung fibroblasts.
The Journal of biological chemistry 2000;275(10):6741-8.
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2000: Lykkesfeldt J; Christen S; Wallock L M; Chang H H; Jacob R A; Ames B N
Ascorbate is depleted by smoking and repleted by moderate supplementation: a study in male smokers and nonsmokers with matched dietary antioxidant intakes.
The American journal of clinical nutrition 2000;71(2):530-6.
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2000: Ames B N; Gold L S
Paracelsus to parascience: the environmental cancer distraction.
Mutation research 2000;447(1):3-13.
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2000: Atamna H; Cheung I; Ames B N
A method for detecting abasic sites in living cells: age-dependent changes in base excision repair.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(2):686-91.
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2000: Hagen T M; Vinarsky V; Wehr C M; Ames B N
(R)-alpha-lipoic acid reverses the age-associated increase in susceptibility of hepatocytes to tert-butylhydroperoxide both in vitro and in vivo.
Antioxidants & redox signaling 2000;2(3):473-83.
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2000: Gogvadze V; Klein S D; Shigenaga M; Ames B N; Richter C
Effect of ebselen on Ca2+ transport in mitochondria.
Redox report : communications in free radical research 2000;5(6):359-63.
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1999: Beckman K B; Ames B N
Endogenous oxidative damage of mtDNA.
Mutation research 1999;424(1-2):51-8.
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1999: Ames B N
Micronutrient deficiencies. A major cause of DNA damage.
Annals of the New York Academy of Sciences 1999;889():87-106.
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1999: Helbock H J; Beckman K B; Ames B N
8-Hydroxydeoxyguanosine and 8-hydroxyguanine as biomarkers of oxidative DNA damage.
Methods in enzymology 1999;300():156-66.
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1999: Yeo H C; Liu J; Helbock H J; Ames B N
Assay of malondialdehyde and other alkanals in biological fluids by gas chromatography-mass spectrometry.
Methods in enzymology 1999;300():70-8.
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1999: Lykkesfeldt J; Ames B N
Ascorbic acid recycling in rat hepatocytes as measurement of antioxidant capacity: decline with age.
Methods in enzymology 1999;299():83-8.
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1998: Hagen T M; Wehr C M; Ames B N
Mitochondrial decay in aging. Reversal through supplementation of acetyl-L-carnitine and N-tert-butyl-alpha-phenyl-nitrone.
Annals of the New York Academy of Sciences 1998;854():214-23.
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1998: Beckman K B; Ames B N
Mitochondrial aging: open questions.
Annals of the New York Academy of Sciences 1998;854():118-27.
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1998: Lykkesfeldt J; Hagen T M; Vinarsky V; Ames B N
Age-associated decline in ascorbic acid concentration, recycling, and biosynthesis in rat hepatocytes--reversal with (R)-alpha-lipoic acid supplementation.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1998;12(12):1183-9.
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1998: Hagen T M; Ingersoll R T; Wehr C M; Lykkesfeldt J; Vinarsky V; Bartholomew J C; Song M H; Ames B N
Acetyl-L-carnitine fed to old rats partially restores mitochondrial function and ambulatory activity.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(16):9562-6.
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1998: Gold L S; Slone T H; Ames B N
What do animal cancer tests tell us about human cancer risk?: Overview of analyses of the carcinogenic potency database.
Drug metabolism reviews 1998;30(2):359-404.
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1998: Ames B N; Gold L S
The prevention of cancer.
Drug metabolism reviews 1998;30(2):201-23.
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1998: Chen Q M; Bartholomew J C; Campisi J; Acosta M; Reagan J D; Ames B N
Molecular analysis of H2O2-induced senescent-like growth arrest in normal human fibroblasts: p53 and Rb control G1 arrest but not cell replication.
The Biochemical journal 1998;332 ( Pt 1)():43-50.
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1998: Helbock H J; Beckman K B; Shigenaga M K; Walter P B; Woodall A A; Yeo H C; Ames B N
DNA oxidation matters: the HPLC-electrochemical detection assay of 8-oxo-deoxyguanosine and 8-oxo-guanine.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(1):288-93.
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1998: Ames B N; Gold L S
The causes and prevention of cancer: the role of environment.
Biotherapy (Dordrecht, Netherlands) 1998;11(2-3):205-20.
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1997: Ames B N; Gold L S
Environmental pollution, pesticides, and the prevention of cancer: misconceptions.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1997;11(13):1041-52.
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1997: Swirsky Gold L; Stern B R; Slone T H; Brown J P; Manley N B; Ames B N
Pesticide residues in food: investigation of disparities in cancer risk estimates.
Cancer letters 1997;117(2):195-207.
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1997: Beckman K B; Ames B N
Oxidative decay of DNA.
The Journal of biological chemistry 1997;272(32):19633-6.
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1997: Ames B N; Gold L S
The causes and prevention of cancer: gaining perspective.
Environmental health perspectives 1997;105 Suppl 4():865-73.
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1997: MacGregor J T; Wehr C M; Hiatt R A; Peters B; Tucker J D; Langlois R G; Jacob R A; Jensen R H; Yager J W; Shigenaga M K; Frei B; Eynon B P; Ames B N
'Spontaneous' genetic damage in man: evaluation of interindividual variability, relationship among markers of damage, and influence of nutritional status.
Mutation research 1997;377(1):125-35.
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1997: Blount B C; Mack M M; Wehr C M; MacGregor J T; Hiatt R A; Wang G; Wickramasinghe S N; Everson R B; Ames B N
Folate deficiency causes uracil misincorporation into human DNA and chromosome breakage: implications for cancer and neuronal damage.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(7):3290-5.
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1997: Christen S; Woodall A A; Shigenaga M K; Southwell-Keely P T; Duncan M W; Ames B N
gamma-tocopherol traps mutagenic electrophiles such as NO(X) and complements alpha-tocopherol: physiological implications.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(7):3217-22.
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1997: Shigenaga M K; Lee H H; Blount B C; Christen S; Shigeno E T; Yip H; Ames B N
Inflammation and NO(X)-induced nitration: assay for 3-nitrotyrosine by HPLC with electrochemical detection.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(7):3211-6.
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1997: Hagen T M; Yowe D L; Bartholomew J C; Wehr C M; Do K L; Park J Y; Ames B N
Mitochondrial decay in hepatocytes from old rats: membrane potential declines, heterogeneity and oxidants increase.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(7):3064-9.
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1997: Liu J; Yeo H C; Doniger S J; Ames B N
Assay of aldehydes from lipid peroxidation: gas chromatography-mass spectrometry compared to thiobarbituric acid.
Analytical biochemistry 1997;245(2):161-6.
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1996: Chen Q; Marsh J; Ames B; Mossman B
Detection of 8-oxo-2'-deoxyguanosine, a marker of oxidative DNA damage, in culture medium from human mesothelial cells exposed to crocidolite asbestos.
Carcinogenesis 1996;17(11):2525-7.
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1996: Liu J; Wang X; Shigenaga M K; Yeo H C; Mori A; Ames B N
Immobilization stress causes oxidative damage to lipid, protein, and DNA in the brain of rats.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1996;10(13):1532-8.
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1996: Liu J; Shigenaga M K; Yan L J; Mori A; Ames B N
Antioxidant activity of diethyldithiocarbamate.
Free radical research 1996;24(6):461-72.
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1996: Fraga C G; Motchnik P A; Wyrobek A J; Rempel D M; Ames B N
Smoking and low antioxidant levels increase oxidative damage to sperm DNA.
Mutation research 1996;351(2):199-203.
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1996: Park J Y; Shigenaga M K; Ames B N
Induction of cytochrome P4501A1 by 2,3,7,8-tetrachlorodibenzo-p-dioxin or indolo(3,2-b)carbazole is associated with oxidative DNA damage.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(6):2322-7.
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1996: Beckman K B; Ames B N
Detection and quantification of oxidative adducts of mitochondrial DNA.
Methods in enzymology 1996;264():442-53.
-
1996: Christen S; Gee P; Ames B N
Mutagenicity of nitric oxide in base pair-specific Salmonella tester strains: TA7000 series.
Methods in enzymology 1996;269():267-78.
-
1996: Helbock H J; Thompson J; Yeo H; Ames B N
N2-methyl-8-oxoguanine: a tRNA urinary metabolite--role of xanthine oxidase.
Free radical biology & medicine 1996;20(3):475-81.
-
1995: Gold L S; Manley N B; Slone T H; Garfinkel G B; Ames B N; Rohrbach L; Stern B R; Chow K
Sixth plot of the carcinogenic potency database: results of animal bioassays published in the General Literature 1989 to 1990 and by the National Toxicology Program 1990 to 1993.
Environmental health perspectives 1995;103 Suppl 8():3-122.
-
1995: Ames B N; Gold L S; Willett W C
The causes and prevention of cancer.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(12):5258-65.
-
1995: Chen Q; Fischer A; Reagan J D; Yan L J; Ames B N
Oxidative DNA damage and senescence of human diploid fibroblast cells.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(10):4337-41.
-
1995: Ames B N; Shigenaga M K; Hagen T M
Mitochondrial decay in aging.
Biochimica et biophysica acta 1995;1271(1):165-70.
-
1994: Hagen T M; Huang S; Curnutte J; Fowler P; Martinez V; Wehr C M; Ames B N; Chisari F V
Extensive oxidative DNA damage in hepatocytes of transgenic mice with chronic active hepatitis destined to develop hepatocellular carcinoma.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(26):12808-12.
-
1994: Gee P; Maron D M; Ames B N
Detection and classification of mutagens: a set of base-specific Salmonella tester strains.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(24):11606-10.
-
1994: Shigenaga M K; Hagen T M; Ames B N
Oxidative damage and mitochondrial decay in aging.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(23):10771-8.
-
1994: Gold L S; Slone T H; Manley N B; Ames B N
Heterocyclic amines formed by cooking food: comparison of bioassay results with other chemicals in the Carcinogenic Potency Database.
Cancer letters 1994;83(1-2):21-9.
-
1994: Yeo H C; Helbock H J; Chyu D W; Ames B N
Assay of malondialdehyde in biological fluids by gas chromatography-mass spectrometry.
Analytical biochemistry 1994;220(2):391-6.
-
1994: Blount B C; Ames B N
Analysis of uracil in DNA by gas chromatography-mass spectrometry.
Analytical biochemistry 1994;219(2):195-200.
-
1994: Chen Q; Ames B N
Senescence-like growth arrest induced by hydrogen peroxide in human diploid fibroblast F65 cells.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(10):4130-4.
-
1994: Fleming S E; Youngman L D; Ames B N
Intestinal cell proliferation is influenced by intakes of protein and energy, aflatoxin, and whole-body radiation.
Nutrition and cancer 1994;22(1):11-30.
-
1994: Shigenaga M K; Aboujaoude E N; Chen Q; Ames B N
Assays of oxidative DNA damage biomarkers 8-oxo-2'-deoxyguanosine and 8-oxoguanine in nuclear DNA and biological fluids by high-performance liquid chromatography with electrochemical detection.
Methods in enzymology 1994;234():16-33.
-
1993: Ames B N; Shigenaga M K; Hagen T M
Oxidants, antioxidants, and the degenerative diseases of aging.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(17):7915-22.
-
1993: Wagner J R; Motchnik P A; Stocker R; Sies H; Ames B N
The oxidation of blood plasma and low density lipoprotein components by chemically generated singlet oxygen.
The Journal of biological chemistry 1993;268(25):18502-6.
-
1993: Olin K L; Shigenaga M K; Ames B N; Golub M S; Gershwin M E; Hendrickx A G; Keen C L
Maternal dietary zinc influences DNA strand break and 8-hydroxy-2'-deoxyguanosine levels in infant rhesus monkey liver.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 1993;203(4):461-6.
-
1993: Viguie C A; Frei B; Shigenaga M K; Ames B N; Packer L; Brooks G A
Antioxidant status and indexes of oxidative stress during consecutive days of exercise.
Journal of applied physiology (Bethesda, Md. : 1985) 1993;75(2):566-72.
-
1993: Gold L S; Manley N B; Slone T H; Garfinkel G B; Rohrbach L; Ames B N
The fifth plot of the Carcinogenic Potency Database: results of animal bioassays published in the general literature through 1988 and by the National Toxicology Program through 1989.
Environmental health perspectives 1993;100():65-168.
-
1993: Helbock H J; Motchnik P A; Ames B N
Toxic hydroperoxides in intravenous lipid emulsions used in preterm infants.
Pediatrics 1993;91(1):83-7.
-
1993: Shigenaga M K; Ames B N
Oxidants and mitogenesis as causes of mutation and cancer: the influence of diet.
Basic life sciences 1993;61():419-36.
-
1993: Blount B C; Ames B N
Development of a sensitive assay for detection of uracil in DNA.
Advances in experimental medicine and biology 1993;338():741-4.
-
1992: Gold L S; Manley N B; Ames B N
Extrapolation of carcinogenicity between species: qualitative and quantitative factors.
Risk analysis : an official publication of the Society for Risk Analysis 1992;12(4):579-88.
-
1992: Ames B N; Shigenaga M K
Oxidants are a major contributor to aging.
Annals of the New York Academy of Sciences 1992;663():85-96.
-
1992: Gold L S; Slone T H; Stern B R; Manley N B; Ames B N
Rodent carcinogens: setting priorities.
Science (New York, N.Y.) 1992;258(5080):261-5.
-
1992: Youngman L D; Park J Y; Ames B N
Protein oxidation associated with aging is reduced by dietary restriction of protein or calories.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(19):9112-6.
-
1992: Wagner J R; Hu C C; Ames B N
Endogenous oxidative damage of deoxycytidine in DNA.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(8):3380-4.
-
1992: Park E M; Shigenaga M K; Degan P; Korn T S; Kitzler J W; Wehr C M; Kolachana P; Ames B N
Assay of excised oxidative DNA lesions: isolation of 8-oxoguanine and its nucleoside derivatives from biological fluids with a monoclonal antibody column.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(8):3375-9.
-
1992: Tartaglia L A; Gimeno C J; Storz G; Ames B N
Multidegenerate DNA recognition by the OxyR transcriptional regulator.
The Journal of biological chemistry 1992;267(3):2038-45.
-
1992: Ames B N; Gold L S
Animal cancer tests and cancer prevention.
Journal of the National Cancer Institute. Monographs 1992;(12):125-32.
-
1991: Gold L S; Slone T H; Manley N B; Garfinkel G B; Hudes E S; Rohrbach L; Ames B N
The Carcinogenic Potency Database: analyses of 4000 chronic animal cancer experiments published in the general literature and by the U.S. National Cancer Institute/National Toxicology Program.
Environmental health perspectives 1991;96():11-5.
-
1991: Fraga C G; Motchnik P A; Shigenaga M K; Helbock H J; Jacob R A; Ames B N
Ascorbic acid protects against endogenous oxidative DNA damage in human sperm.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(24):11003-6.
-
1991: Ames B N; Gold L S
Endogenous mutagens and the causes of aging and cancer.
Mutation research 1991;250(1-2):3-16.
-
1991: Frei B; Forte T M; Ames B N; Cross C E
Gas phase oxidants of cigarette smoke induce lipid peroxidation and changes in lipoprotein properties in human blood plasma. Protective effects of ascorbic acid.
The Biochemical journal 1991;277 ( Pt 1)():133-8.
-
1991: Degan P; Shigenaga M K; Park E M; Alperin P E; Ames B N
Immunoaffinity isolation of urinary 8-hydroxy-2'-deoxyguanosine and 8-hydroxyguanine and quantitation of 8-hydroxy-2'-deoxyguanosine in DNA by polyclonal antibodies.
Carcinogenesis 1991;12(5):865-71.
-
1991: Ames B N
Natural carcinogens and dioxin.
The Science of the total environment 1991;104(1-2):159-66.
-
1991: Shigenaga M K; Ames B N
Assays for 8-hydroxy-2'-deoxyguanosine: a biomarker of in vivo oxidative DNA damage.
Free radical biology & medicine 1991;10(3-4):211-6.
-
1990: Gold L S; Bernstein L; Ames B N
The importance of ranking possible carcinogenic hazards using HERP.
Risk analysis : an official publication of the Society for Risk Analysis 1990;10(4):625-8; discussion 629-33.
-
1990: MacGregor J T; Schlegel R; Wehr C M; Alperin P; Ames B N
Cytogenetic damage induced by folate deficiency in mice is enhanced by caffeine.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(24):9962-5.
-
1990: Ames B N; Profet M; Gold L S
Nature's chemicals and synthetic chemicals: comparative toxicology.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(19):7782-6.
-
1990: Ames B N; Profet M; Gold L S
Dietary pesticides (99.99% all natural).
Proceedings of the National Academy of Sciences of the United States of America 1990;87(19):7777-81.
-
1990: Ames B N; Gold L S
Chemical carcinogenesis: too many rodent carcinogens.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(19):7772-6.
-
1990: Ames B N; Gold L S
Too many rodent carcinogens: mitogenesis increases mutagenesis.
Science (New York, N.Y.) 1990;249(4972):970-1.
-
1990: Frei B; Kim M C; Ames B N
Ubiquinol-10 is an effective lipid-soluble antioxidant at physiological concentrations.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(12):4879-83.
-
1990: Fraga C G; Shigenaga M K; Park J W; Degan P; Ames B N
Oxidative damage to DNA during aging: 8-hydroxy-2'-deoxyguanosine in rat organ DNA and urine.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(12):4533-7.
-
1990: Tartaglia L A; Storz G; Brodsky M H; Lai A; Ames B N
Alkyl hydroperoxide reductase from Salmonella typhimurium. Sequence and homology to thioredoxin reductase and other flavoprotein disulfide oxidoreductases.
The Journal of biological chemistry 1990;265(18):10535-40.
-
1990: Cross C E; Forte T; Stocker R; Louie S; Yamamoto Y; Ames B N; Frei B
Oxidative stress and abnormal cholesterol metabolism in patients with adult respiratory distress syndrome.
The Journal of laboratory and clinical medicine 1990;115(4):396-404.
-
1990: Storz G; Tartaglia L A; Ames B N
Transcriptional regulator of oxidative stress-inducible genes: direct activation by oxidation.
Science (New York, N.Y.) 1990;248(4952):189-94.
-
1990: Gold L S; Slone T H; Backman G M; Eisenberg S; Da Costa M; Wong M; Manley N B; Rohrbach L; Ames B N
Third chronological supplement to the carcinogenic potency database: standardized results of animal bioassays published through December 1986 and by the National Toxicology Program through June 1987.
Environmental health perspectives 1990;84():215-86.
-
1990: Frei B; Stocker R; England L; Ames B N
Ascorbate: the most effective antioxidant in human blood plasma.
Advances in experimental medicine and biology 1990;264():155-63.
-
1990: Ames B N; Gold L S
Dietary carcinogens, environmental pollution, and cancer: some misconceptions.
Medical oncology and tumor pharmacotherapy 1990;7(2-3):69-85.
-
1990: Ames B N; Gold L S
Natural chemicals, synthetic chemicals, risk assessment, and cancer.
Princess Takamatsu symposia 1990;21():303-14.
-
1989: Tartaglia L A; Storz G; Ames B N
Identification and molecular analysis of oxyR-regulated promoters important for the bacterial adaptation to oxidative stress.
Journal of molecular biology 1989;210(4):709-19.
-
1989: Shigenaga M K; Gimeno C J; Ames B N
Urinary 8-hydroxy-2'-deoxyguanosine as a biological marker of in vivo oxidative DNA damage.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(24):9697-701.
-
1989: Ames B N
Endogenous DNA damage as related to cancer and aging.
Mutation research 1989;214(1):41-6.
-
1989: Frei B; England L; Ames B N
Ascorbate is an outstanding antioxidant in human blood plasma.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(16):6377-81.
-
1989: Farr S B; Arnosti D N; Chamberlin M J; Ames B N
An apaH mutation causes AppppA to accumulate and affects motility and catabolite repression in Escherichia coli.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(13):5010-4.
-
1989: Park J W; Cundy K C; Ames B N
Detection of DNA adducts by high-performance liquid chromatography with electrochemical detection.
Carcinogenesis 1989;10(5):827-32.
-
1989: Christman M F; Storz G; Ames B N
OxyR, a positive regulator of hydrogen peroxide-inducible genes in Escherichia coli and Salmonella typhimurium, is homologous to a family of bacterial regulatory proteins.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(10):3484-8.
-
1989: Storz G; Jacobson F S; Tartaglia L A; Morgan R W; Silveira L A; Ames B N
An alkyl hydroperoxide reductase induced by oxidative stress in Salmonella typhimurium and Escherichia coli: genetic characterization and cloning of ahp.
Journal of bacteriology 1989;171(4):2049-55.
-
1989: Blum P H; Ames B N
Immunochemical identification of a tRNA-independent cytokinin-like compound in Salmonella typhimurium.
Biochimica et biophysica acta 1989;1007(2):196-202.
-
1989: Jacobson F S; Morgan R W; Christman M F; Ames B N
An alkyl hydroperoxide reductase from Salmonella typhimurium involved in the defense of DNA against oxidative damage. Purification and properties.
The Journal of biological chemistry 1989;264(3):1488-96.
-
1989: Ames B N
Endogenous oxidative DNA damage, aging, and cancer.
Free radical research communications 1989;7(3-6):121-8.
-
1989: Ames B N
Mutagenesis and carcinogenesis: endogenous and exogenous factors.
Environmental and molecular mutagenesis 1989;14 Suppl 16():66-77.
-
1988: Frei B; Stocker R; Ames B N
Antioxidant defenses and lipid peroxidation in human blood plasma.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(24):9748-52.
-
1988: Frei B; Yamamoto Y; Niclas D; Ames B N
Evaluation of an isoluminol chemiluminescence assay for the detection of hydroperoxides in human blood plasma.
Analytical biochemistry 1988;175(1):120-30.
-
1988: Park J W; Ames B N
7-Methylguanine adducts in DNA are normally present at high levels and increase on aging: analysis by HPLC with electrochemical detection.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(20):7467-70.
-
1988: Richter C; Park J W; Ames B N
Normal oxidative damage to mitochondrial and nuclear DNA is extensive.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(17):6465-7.
-
1988: Kramer G F; Ames B N
Mechanisms of mutagenicity and toxicity of sodium selenite (Na2SeO3) in Salmonella typhimurium.
Mutation research 1988;201(1):169-80.
-
1988: Baker J C; Ames B N
Alterations in levels of 5'-adenyl dinucleotides following DNA damage in normal human fibroblasts and fibroblasts derived from patients with xeroderma pigmentosum.
Mutation research 1988;208(2):87-93.
-
1988: Kohen R; Yamamoto Y; Cundy K C; Ames B N
Antioxidant activity of carnosine, homocarnosine, and anserine present in muscle and brain.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(9):3175-9.
-
1988: Kramer G F; Baker J C; Ames B N
Near-UV stress in Salmonella typhimurium: 4-thiouridine in tRNA, ppGpp, and ApppGpp as components of an adaptive response.
Journal of bacteriology 1988;170(5):2344-51.
-
1988: Adelman R; Saul R L; Ames B N
Oxidative damage to DNA: relation to species metabolic rate and life span.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(8):2706-8.
-
1988: Kramer G F; Ames B N
Isolation and characterization of a selenium metabolism mutant of Salmonella typhimurium.
Journal of bacteriology 1988;170(2):736-43.
-
1988: Cundy K C; Kohen R; Ames B N
Determination of 8-hydroxydeoxyguanosine in human urine: a possible assay for in vivo oxidative DNA damage.
Basic life sciences 1988;49():479-82.
-
1988: Ames B N
Measuring oxidative damage in humans: relation to cancer and ageing.
IARC scientific publications 1988;(89):407-16.
-
1988: Baker J C; Ames B N
Alterations of NAD and adenylyl dinucleotide metabolism in Chediak-Higashi syndrome fibroblasts.
Journal of inherited metabolic disease 1988;11(3):221-8.
-
1987: Ames B N
Six common errors relating to environmental pollution.
Regulatory toxicology and pharmacology : RTP 1987;7(4):379-83.
-
1987: Storz G; Christman M F; Sies H; Ames B N
Spontaneous mutagenesis and oxidative damage to DNA in Salmonella typhimurium.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(24):8917-21.
-
1987: Stocker R; Ames B N
Potential role of conjugated bilirubin and copper in the metabolism of lipid peroxides in bile.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(22):8130-4.
-
1987: Baker J C; Smale S T; Tjian R; Ames B N
Inhibition of simian virus 40 DNA replication in vitro by poly(ADP-ribosyl)ated diadenosine tetraphosphate.
The Journal of biological chemistry 1987;262(31):14855-8.
-
1987: Gold L S; Slone T H; Backman G M; Magaw R; Da Costa M; Lopipero P; Blumenthal M; Ames B N
Second chronological supplement to the Carcinogenic Potency Database: standardized results of animal bioassays published through December 1984 and by the National Toxicology Program through May 1986.
Environmental health perspectives 1987;74():237-329.
-
1987: Ames B N; Magaw R; Gold L S
Ranking possible carcinogenic hazards.
Science (New York, N.Y.) 1987;236(4799):271-80.
-
1987: Yamamoto Y; Ames B N
Detection of lipid hydroperoxides and hydrogen peroxide at picomole levels by an HPLC and isoluminol chemiluminescence assay.
Free radical biology & medicine 1987;3(5):359-61.
-
1986: Morgan R W; Christman M F; Jacobson F S; Storz G; Ames B N
Hydrogen peroxide-inducible proteins in Salmonella typhimurium overlap with heat shock and other stress proteins.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(21):8059-63.
-
1986: Gold L S; de Veciana M; Backman G M; Magaw R; Lopipero P; Smith M; Blumenthal M; Levinson R; Bernstein L; Ames B N
Chronological supplement to the Carcinogenic Potency Database: standardized results of animal bioassays published through December 1982.
Environmental health perspectives 1986;67():161-200.
-
1985: Christman M F; Morgan R W; Jacobson F S; Ames B N
Positive control of a regulon for defenses against oxidative stress and some heat-shock proteins in Salmonella typhimurium.
Cell 1985;41(3):753-62.
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