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Paul Dijkhuizen

Research Profile

Chemicals & Drugs

Physiology

Nerve Regeneration

Living Beings

Devices

Gene Transfer Techniques

Anatomy

Disorders

Spinal Cord Injuries

Procedures

Genetic Therapy

Genes & Molecular Sequences

Co-author Network

Publications

TOP 3
Colin J D Ross; Jaap Twisk; Andrew C Bakker; Fudan Miao; Dennis Verbart; Jaap Rip; Tamara Godbey; Paul A Dijkhuizen; Wim T Hermens; John J P Kastelein; Jan Albert Kuivenhoven; Janneke M Meulenberg; Michael R Hayden
Correction of feline lipoprotein lipase deficiency with adeno-associated virus serotype 1-mediated gene transfer of the lipoprotein lipase S447X beneficial mutation.
Jaap Rip; Melchior C Nierman; Jeroen A Sierts; Wilma Petersen; Karin van den Oever; Daniel Van Raalte; Colin J D Ross; Michael R Hayden; Andrew C Bakker; Paul A Dijkhuizen; Wim T Hermens; Jaap Twisk; Erik S G Stroes; John J P Kastelein; Jan Albert Kuivenhoven; Janneke M Meulenberg
Gene therapy for lipoprotein lipase deficiency: working toward clinical application.
Bas Blits; Thomas P Carlstedt; Marc J Ruitenberg; Fred De Winter; Wim T Hermens; Paul A Dijkhuizen; Jill W C Claasens; Ruben Eggers; Ronald van der Sluis; Liliane Tenenbaum; Gerard J Boer; Joost Verhaagen
Rescue and sprouting of motoneurons following ventral root avulsion and reimplantation combined with intraspinal adeno-associated viral vector-mediated expression of glial cell line-derived neurotrophic factor or brain-derived neurotrophic factor.

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All Publications

2006: Colin J D Ross; Jaap Twisk; Andrew C Bakker; Fudan Miao; Dennis Verbart; Jaap Rip; Tamara Godbey; Paul A Dijkhuizen; Wim T Hermens; John J P Kastelein; Jan Albert Kuivenhoven; Janneke M Meulenberg; Michael R Hayden
Correction of feline lipoprotein lipase deficiency with adeno-associated virus serotype 1-mediated gene transfer of the lipoprotein lipase S447X beneficial mutation.
Human gene therapy 2006;17(5):487-99.
2005: Jaap Rip; Melchior C Nierman; Jeroen A Sierts; Wilma Petersen; Karin van den Oever; Daniel Van Raalte; Colin J D Ross; Michael R Hayden; Andrew C Bakker; Paul A Dijkhuizen; Wim T Hermens; Jaap Twisk; Erik S G Stroes; John J P Kastelein; Jan Albert Kuivenhoven; Janneke M Meulenberg
Gene therapy for lipoprotein lipase deficiency: working toward clinical application.
Human gene therapy 2005;16(11):1276-86.
2004: Bas Blits; Thomas P Carlstedt; Marc J Ruitenberg; Fred De Winter; Wim T Hermens; Paul A Dijkhuizen; Jill W C Claasens; Ruben Eggers; Ronald van der Sluis; Liliane Tenenbaum; Gerard J Boer; Joost Verhaagen
Rescue and sprouting of motoneurons following ventral root avulsion and reimplantation combined with intraspinal adeno-associated viral vector-mediated expression of glial cell line-derived neurotrophic factor or brain-derived neurotrophic factor.
Experimental neurology 2004;189(2):303-16.
2004: Marc J Ruitenberg; Bas Blits; Paul A Dijkhuizen; Erik T te Beek; Arne Bakker; Joop J Van Heerikhuize; Chris W Pool; Wim T Hermens; Gerard J Boer; Joost Verhaagen
Adeno-associated viral vector-mediated gene transfer of brain-derived neurotrophic factor reverses atrophy of rubrospinal neurons following both acute and chronic spinal cord injury.
Neurobiology of disease 2004;15(2):394-406.
2003: Marc J Ruitenberg; Giles W Plant; Frank P T Hamers; Joke Wortel; Bas Blits; Paul A Dijkhuizen; Willem Hendrik Gispen; Gerard J Boer; Joost Verhaagen
Ex vivo adenoviral vector-mediated neurotrophin gene transfer to olfactory ensheathing glia: effects on rubrospinal tract regeneration, lesion size, and functional recovery after implantation in the injured rat spinal cord.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003;23(18):7045-58.
2002: R W H Verwer; Wim T Hermens; Paul A Dijkhuizen; Olivier ter Brake; Robert E Baker; Ahmad Salehi; Arja A Sluiter; Marloes J M Kok; Linda J Muller; Joost Verhaagen; Dick F Swaab
Cells in human postmortem brain tissue slices remain alive for several weeks in culture.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002;16(1):54-60.
2001: Gerard J Boer; KE van Esseveldt; Paul A Dijkhuizen; Wim T Hermens; E T te Beek; Joop J Van Heerikhuize; H A Poldervaart; Joost Verhaagen
Adenoviral vector-mediated expression of neurotrophin-3 increases neuronal survival in suprachiasmatic nucleus grafts.
Experimental neurology 2001;169(2):364-75.
2000: Bas Blits; Paul A Dijkhuizen; Gerard J Boer; Joost Verhaagen
Intercostal nerve implants transduced with an adenoviral vector encoding neurotrophin-3 promote regrowth of injured rat corticospinal tract fibers and improve hindlimb function.
Experimental neurology 2000;164(1):25-37.
2000: Bas Blits; Paul A Dijkhuizen; Wim T Hermens; L K Van Esseveldt; Gerard J Boer; Joost Verhaagen
The use of adenoviral vectors and ex vivo transduced neurotransplants: towards promotion of neuroregeneration.
Cell transplantation 2000;9(2):169-78.
1999: Bas Blits; Paul A Dijkhuizen; T P Carlstedt; H Poldervaart; S Schiemanck; Gerard J Boer; Joost Verhaagen
Adenoviral vector-mediated expression of a foreign gene in peripheral nerve tissue bridges implanted in the injured peripheral and central nervous system.
Experimental neurology 1999;160(1):256-67.
1999: Wim T Hermens; Olivier ter Brake; Paul A Dijkhuizen; M A F Sonnemans; D Grimm; J A Kleinschmidt; Joost Verhaagen
Purification of recombinant adeno-associated virus by iodixanol gradient ultracentrifugation allows rapid and reproducible preparation of vector stocks for gene transfer in the nervous system.
Human gene therapy 1999;10(11):1885-91.
1999: G C Hassink; KE van Esseveldt; Paul A Dijkhuizen; Joost Verhaagen; Gerard J Boer
Ontogeny of neurotrophin receptor trkC expression in the rat forebrain and anterior hypothalamus with emphasis on the suprachiasmatic nucleus.
Neuroscience 1999;92(2):705-12.
1998: Yi Zhang; Paul A Dijkhuizen; Patrick N Anderson; A Robert Lieberman; Joost Verhaagen
NT-3 delivered by an adenoviral vector induces injured dorsal root axons to regenerate into the spinal cord of adult rats.
Journal of neuroscience research 1998;54(4):554-62.
1998: Paul A Dijkhuizen; R Jeroen Pasterkamp; Wim T Hermens; Fred De Winter; Roman J Giger; Joost Verhaagen
Adenoviral vector-mediated gene delivery to injured rat peripheral nerve.
Journal of neurotrauma 1998;15(6):387-97.
1998: Robert E Baker; Paul A Dijkhuizen; Jaap van Pelt; Joost Verhaagen
Growth of pyramidal, but not non-pyramidal, dendrites in long-term organotypic explants of neonatal rat neocortex chronically exposed to neurotrophin-3.
The European journal of neuroscience 1998;10(3):1037-44.
1997: Paul A Dijkhuizen; Wim T Hermens; M A Teunis; Joost Verhaagen
Adenoviral vector-directed expression of neurotrophin-3 in rat dorsal root ganglion explants results in a robust neurite outgrowth response.
Journal of neurobiology 1997;33(2):172-84.
1997: Wim T Hermens; Roman J Giger; Anthony J G D Holtmaat; Paul A Dijkhuizen; D A Houweling; Joost Verhaagen
Transient gene transfer to neurons and glia: analysis of adenoviral vector performance in the CNS and PNS.
Journal of neuroscience methods 1997;71(1):85-98.
1996: Ahmad Salehi; Joost Verhaagen; Paul A Dijkhuizen; Dick F Swaab
Co-localization of high-affinity neurotrophin receptors in nucleus basalis of Meynert neurons and their differential reduction in Alzheimer's disease.
Neuroscience 1996;75(2):373-87.
1995: Anthony J G D Holtmaat; Paul A Dijkhuizen; AB Oestreicher; HJ Romijn; N M Van der Lugt; A Berns; Frank L Margolis; Willem Hendrik Gispen; Joost Verhaagen
Directed expression of the growth-associated protein B-50/GAP-43 to olfactory neurons in transgenic mice results in changes in axon morphology and extraglomerular fiber growth.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1995;15(12):7953-65.
1995: Joost Verhaagen; Wim T Hermens; Paul A Dijkhuizen; Anthony J G D Holtmaat; Willem Hendrik Gispen
Use of viral vectors to promote neuroregeneration.
Clinical neuroscience (New York, N.Y.) 1995;3(5):275-83.