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Bauke Dijkstra

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Marcus Schallmey; Hein J Wijma; Peter A Jekel; Michael Breuer; Bauke W Dijkstra; Robert J Floor; Bernhard Hauer; Dick B Janssen
Biocatalytic and structural properties of a highly engineered halohydrin dehalogenase.
Hans Leemhuis; Tjaard Pijning; Sander S van Leeuwen; Bauke W Dijkstra; Justyna Malgorzata Dobruchowska; Slavko Kralj; Lubbert Dijkhuizen
Glucansucrases: three-dimensional structures, reactions, mechanism, α-glucan analysis and their implications in biotechnology and food applications.
Ciprian G Crismaru; Stefaan De Wildeman; Bauke W Dijkstra; Ben L Feringa; Gerrit J Poelarends; Wiktor Szymanski; Hein J Wijma; Bian Wu; Gjalt G Wybenga; Sebastian Bartsch; Dick B Janssen
Biochemical properties and crystal structure of a β-phenylalanine aminotransferase from Variovorax paradoxus.

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2013: Marcus Schallmey; Hein J Wijma; Peter A Jekel; Michael Breuer; Bauke W Dijkstra; Robert J Floor; Bernhard Hauer; Dick B Janssen
Biocatalytic and structural properties of a highly engineered halohydrin dehalogenase.
Chembiochem : a European journal of chemical biology 2013;14(7):870-81.
2013: Hans Leemhuis; Tjaard Pijning; Sander S van Leeuwen; Bauke W Dijkstra; Justyna Malgorzata Dobruchowska; Slavko Kralj; Lubbert Dijkhuizen
Glucansucrases: three-dimensional structures, reactions, mechanism, α-glucan analysis and their implications in biotechnology and food applications.
Journal of biotechnology 2013;163(2):250-72.
2013: Ciprian G Crismaru; Stefaan De Wildeman; Bauke W Dijkstra; Ben L Feringa; Gerrit J Poelarends; Wiktor Szymanski; Hein J Wijma; Bian Wu; Gjalt G Wybenga; Sebastian Bartsch; Dick B Janssen
Biochemical properties and crystal structure of a β-phenylalanine aminotransferase from Variovorax paradoxus.
Applied and environmental microbiology 2013;79(1):185-95.
2012: Tjaard Pijning; Andreja Vujičić-Žagar; Lubbert Dijkhuizen; Slavko Kralj; Bauke W Dijkstra
Structure of the α-1,6/α-1,4-specific glucansucrase GTFA from Lactobacillus reuteri 121.
Acta crystallographica. Section F, Structural biology and crystallization communications 2012;68(Pt 12):1448-54.
2012: Ganesh Ram R Visweswaran; Bauke W Dijkstra; Jan Kok
A genetically engineered protein domain binding to bacterial murein, archaeal pseudomurein, and fungal chitin cell wall material.
Applied microbiology and biotechnology 2012;96(3):729-37.
2012: Munir A Anwar; Bauke W Dijkstra; Slavko Kralj; Hans Leemhuis; Tjaard Pijning; Lubbert Dijkhuizen
The role of conserved inulosucrase residues in the reaction and product specificity of Lactobacillus reuteri inulosucrase.
The FEBS journal 2012;279(19):3612-21.
2012: Niels van Oosterwijk; Lubbert Dijkhuizen; Jan Knol; Robert van der Geize; Bauke W Dijkstra
Structure and catalytic mechanism of 3-ketosteroid-Delta4-(5α)-dehydrogenase from Rhodococcus jostii RHA1 genome.
The Journal of biological chemistry 2012;287(37):30975-83.
2012: Gjalt G Wybenga; Dick B Janssen; Ciprian G Crismaru; Bauke W Dijkstra
Structural determinants of the β-selectivity of a bacterial aminotransferase.
The Journal of biological chemistry 2012;287(34):28495-502.
2012: Ali Rohman; Niels van Oosterwijk; Bauke W Dijkstra
Purification, crystallization and preliminary X-ray crystallographic analysis of 3-ketosteroid Δ1-dehydrogenase from Rhodococcus erythropolis SQ1.
Acta crystallographica. Section F, Structural biology and crystallization communications 2012;68(Pt 5):551-6.
2012: Wojciech Augustyniak; Rolf Boelens; Agnieszka A Brzezinska; Bauke W Dijkstra; Tjaard Pijning; Hans Wienk; Manfred T Reetz
Biophysical characterization of mutants of Bacillus subtilis lipase evolved for thermostability: factors contributing to increased activity retention.
Protein science : a publication of the Protein Society 2012;21(4):487-97.
2012: Luis F Godinho; Gerrit J Poelarends; Frank J Dekker; Bauke W Dijkstra; Carlos R Reis; Henriëtte J Rozeboom; Wim J Quax
Enhancement of the enantioselectivity of carboxylesterase A by structure-based mutagenesis.
Journal of biotechnology 2012;158(1-2):36-43.
2012: Yoann Brison; Yannick Malbert; Pierre Monsan; Sandrine Morel; Lionel Mourey; Tjaard Pijning; Gabrielle Potocki-Véronèse; Magali Remaud-Siméon; Samuel Tranier; Émeline Fabre; Bauke W Dijkstra
Functional and structural characterization of α-(1->2) branching sucrase derived from DSR-E glucansucrase.
The Journal of biological chemistry 2012;287(11):7915-24.
2012: Milena Opačić; Bauke W Dijkstra; Fabrizia Fusetti; Ben H Hesp; Jaap Broos
Structural investigation of the transmembrane C domain of the mannitol permease from Escherichia coli using 5-FTrp fluorescence spectroscopy.
Biochimica et biophysica acta 2012;1818(3):861-8.
2012: Bian Wu; Gjalt G Wybenga; Gerrit J Poelarends; Wiktor Szymański; Sebastian Bartsch; Stefaan De Wildeman; Bauke W Dijkstra; Ben L Feringa; Matthew M Heberling; Dick B Janssen
Mechanism-inspired engineering of phenylalanine aminomutase for enhanced β-regioselective asymmetric amination of cinnamates.
Angewandte Chemie (International ed. in English) 2012;51(2):482-6.
2012: Vincent J B Ruigrok; Hauke Smidt; Bauke W Dijkstra; Johan Hekelaar; Mark Levisson; John van der Oost
Characterization of Aptamer-Protein Complexes by X-ray Crystallography and Alternative Approaches.
International journal of molecular sciences 2012;13(8):10537-52.
2011: Ganesh Ram R Visweswaran; Bauke W Dijkstra; Jan Kok
Murein and pseudomurein cell wall binding domains of bacteria and archaea--a comparative view.
Applied microbiology and biotechnology 2011;92(5):921-8.
2011: Niels van Oosterwijk; Lubbert Dijkhuizen; Jan Knol; Robert van der Geize; Bauke W Dijkstra
Cloning, overexpression, purification, crystallization and preliminary X-ray analysis of 3-ketosteroid Δ(4)-(5α)-dehydrogenase from Rhodococcus jostii RHA1.
Acta crystallographica. Section F, Structural biology and crystallization communications 2011;67(Pt 10):1269-73.
2011: Tjaard Pijning; Justyna Malgorzata Dobruchowska; Slavko Kralj; Hans Leemhuis; Munir A Anwar; Markus Böger; Lubbert Dijkhuizen; Bauke W Dijkstra
Crystal structure of inulosucrase from Lactobacillus: insights into the substrate specificity and product specificity of GH68 fructansucrases.
Journal of molecular biology 2011;412(1):80-93.
2011: Wangsa T Ismaya; Henriëtte J Rozeboom; Marloes Schurink; Carmen G Boeriu; Harry Wichers; Bauke W Dijkstra
Crystallization and preliminary X-ray crystallographic analysis of tyrosinase from the mushroom Agaricus bisporus.
Acta crystallographica. Section F, Structural biology and crystallization communications 2011;67(Pt 5):575-8.
2011: Marta Palomo; Tjaard Pijning; Thijs Booiman; Justyna Malgorzata Dobruchowska; Jeroen van der Vlist; Slavko Kralj; Antoni Planas; Katja Loos; Johannis P Kamerling; Bauke W Dijkstra; M J E C van der Maarel; Lubbert Dijkhuizen; Hans Leemhuis
Thermus thermophilus glycoside hydrolase family 57 branching enzyme: crystal structure, mechanism of action, and products formed.
The Journal of biological chemistry 2011;286(5):3520-30.
2011: Ganesh Ram R Visweswaran; Bauke W Dijkstra; Jan Kok
A minimum of three motifs is essential for optimal binding of pseudomurein cell wall-binding domain of Methanothermobacter thermautotrophicus.
PloS one 2011;6(6):e21582.
2010: Andreja Vujicic-Zagar; Tjaard Pijning; Slavko Kralj; Cesar A López; Wieger Eeuwema; Lubbert Dijkhuizen; Bauke W Dijkstra
Crystal structure of a 117 kDa glucansucrase fragment provides insight into evolution and product specificity of GH70 enzymes.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(50):21406-11.
2010: Avinash Kale; Tjaard Pijning; Theo Sonke; Bauke W Dijkstra; Andy-Mark W H Thunnissen
Crystal structure of the leucine aminopeptidase from Pseudomonas putida reveals the molecular basis for its enantioselectivity and broad substrate specificity.
Journal of molecular biology 2010;398(5):703-14.
2010: Marcel Bokhove; Hiromi Yoshida; Charles M H Hensgens; Jan-Metske van der Laan; John D Sutherland; Bauke W Dijkstra
Structures of an isopenicillin N converting Ntn-hydrolase reveal different catalytic roles for the active site residues of precursor and mature enzyme.
Structure (London, England : 1993) 2010;18(3):301-8.
2010: Marcel Bokhove; Pol Nadal Jimenez; Wim J Quax; Bauke W Dijkstra
The quorum-quenching N-acyl homoserine lactone acylase PvdQ is an Ntn-hydrolase with an unusual substrate-binding pocket.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(2):686-91.
2010: Ganesh Ram R Visweswaran; Bauke W Dijkstra; Jan Kok
Two major archaeal pseudomurein endoisopeptidases: PeiW and PeiP.
Archaea (Vancouver, B.C.) 2010;2010():480492.
2009: Tjaard Pijning; Gertie van Pouderoyen; Leon D Kluskens; John van der Oost; Bauke W Dijkstra
The crystal structure of a hyperthermoactive exopolygalacturonase from Thermotoga maritima reveals a unique tetramer.
FEBS letters 2009;583(22):3665-70.
2009: Ashok Kumar Patel; Niels van Oosterwijk; Vijay Kumar Singh; Henriëtte J Rozeboom; Kor H Kalk; Roland Siezen; Medicherla V Jagannadham; Bauke W Dijkstra
Crystallization and preliminary X-ray analysis of carnein, a serine protease from Ipomoea carnea.
Acta crystallographica. Section F, Structural biology and crystallization communications 2009;65(Pt 4):383-5.
2009: Mark Levisson; Lei Sun; Sjon Hendriks; Peter Swinkels; Twan Akveld; Jelle B Bultema; Arjan Barendregt; Robert H H van den Heuvel; Bauke W Dijkstra; John van der Oost; Servé W M Kengen
Crystal structure and biochemical properties of a novel thermostable esterase containing an immunoglobulin-like domain.
Journal of molecular biology 2009;385(3):949-62.
2008: Henriëtte J Rozeboom; Tonje M Bjerkan; Kor H Kalk; Helga Ertesvåg; Synnøve Holtan; Finn L Aachmann; Svein Valla; Bauke W Dijkstra
Structural and mutational characterization of the catalytic A-module of the mannuronan C-5-epimerase AlgE4 from Azotobacter vinelandii.
The Journal of biological chemistry 2008;283(35):23819-28.
2008: Ykelien L Boersma; Tjaard Pijning; Margriet S Bosma; Almer M van der Sloot; Luís F Godinho; Melloney J Dröge; Remko T Winter; Gertie van Pouderoyen; Bauke W Dijkstra; Wim J Quax
Loop grafting of Bacillus subtilis lipase A: inversion of enantioselectivity.
Chemistry & biology 2008;15(8):782-9.
2008: Ronan M Kelly; Hans Leemhuis; Henriëtte J Rozeboom; Niels van Oosterwijk; Bauke W Dijkstra; Lubbert Dijkhuizen
Elimination of competing hydrolysis and coupling side reactions of a cyclodextrin glucanotransferase by directed evolution.
The Biochemical journal 2008;413(3):517-25.
2008: Ykelien L Boersma; Melloney J Dröge; Almer van der Sloot; Tjaard Pijning; Robbert Cool; Bauke W Dijkstra; Wim J Quax
A novel genetic selection system for improved enantioselectivity of Bacillus subtilis lipase A.
Chembiochem : a European journal of chemical biology 2008;9(7):1110-5.
2007: Ali Rohman; Niels van Oosterwijk; Slavko Kralj; Lubbert Dijkhuizen; Bauke W Dijkstra; Ni Nyoman Tri Puspaningsih
Purification, crystallization and preliminary X-ray analysis of a thermostable glycoside hydrolase family 43 beta-xylosidase from Geobacillus thermoleovorans IT-08.
Acta crystallographica. Section F, Structural biology and crystallization communications 2007;63(Pt 11):932-5.
2007: Lei Sun; Mark Levisson; Sjon Hendriks; Twan Akveld; Servé W M Kengen; Bauke W Dijkstra; John van der Oost
Crystallization and preliminary crystallographic analysis of an esterase with a novel domain from the hyperthermophile Thermotoga maritima.
Acta crystallographica. Section F, Structural biology and crystallization communications 2007;63(Pt 9):777-9.
2007: Jan J W Tiesinga; Gertie van Pouderoyen; Marco Nardini; Stéphane Ransac; Bauke W Dijkstra
Structural basis of phospholipase activity of Staphylococcus hyicus lipase.
Journal of molecular biology 2007;371(2):447-56.
2007: Karin E Van Straaten; Thomas R M Barends; Bauke W Dijkstra; Andy-Mark W H Thunnissen
Structure of Escherichia coli Lytic transglycosylase MltA with bound chitohexaose: implications for peptidoglycan binding and cleavage.
The Journal of biological chemistry 2007;282(29):21197-205.
2007: Thomas R M Barends; Jelle B Bultema; Thijs Kaper; M J E C van der Maarel; Lubbert Dijkhuizen; Bauke W Dijkstra
Three-way stabilization of the covalent intermediate in amylomaltase, an alpha-amylase-like transglycosylase.
The Journal of biological chemistry 2007;282(23):17242-9.
2007: Thijs Kaper; Hans Leemhuis; Joost C M Uitdehaag; Bart A van der Veen; Bauke W Dijkstra; M J E C van der Maarel; Lubbert Dijkhuizen
Identification of acceptor substrate binding subsites +2 and +3 in the amylomaltase from Thermus thermophilus HB8.
Biochemistry 2007;46(17):5261-9.
2007: Suzanne Wolterink-van Loo; André van Eerde; Marco A J Siemerink; Jasper Akerboom; Bauke W Dijkstra; John van der Oost
Biochemical and structural exploration of the catalytic capacity of Sulfolobus KDG aldolases.
The Biochemical journal 2007;403(3):421-30.
2007: René M de Jong; Paola Bazzacco; Gerrit J Poelarends; William H Johnson; Yoon Jae Kim; Elizabeth A Burks; Hector Serrano; Andy-Mark W H Thunnissen; Christian P Whitman; Bauke W Dijkstra
Crystal structures of native and inactivated cis-3-chloroacrylic acid dehalogenase. Structural basis for substrate specificity and inactivation by (R)-oxirane-2-carboxylate.
The Journal of biological chemistry 2007;282(4):2440-9.
2006: André van Eerde; Suzanne Wolterink-van Loo; John van der Oost; Bauke W Dijkstra
Fortuitous structure determination of 'as-isolated' Escherichia coli bacterioferritin in a novel crystal form.
Acta crystallographica. Section F, Structural biology and crystallization communications 2006;62(Pt 11):1061-6.
2006: A Vujicić-Zagar; Bauke W Dijkstra
Monoclinic crystal form of Aspergillus niger alpha-amylase in complex with maltose at 1.8 angstroms resolution.
Acta crystallographica. Section F, Structural biology and crystallization communications 2006;62(Pt 8):716-21.
2006: Cyril Hamiaux; André van Eerde; Claude Parsot; Jaap Broos; Bauke W Dijkstra
Structural mimicry for vinculin activation by IpaA, a virulence factor of Shigella flexneri.
EMBO reports 2006;7(8):794-9.
2006: René M de Jong; Kor H Kalk; Lixia Tang; Dick B Janssen; Bauke W Dijkstra
The X-ray structure of the haloalcohol dehalogenase HheA from Arthrobacter sp. strain AD2: insight into enantioselectivity and halide binding in the haloalcohol dehalogenase family.
Journal of bacteriology 2006;188(11):4051-6.
2006: Thomas R M Barends; Jolanda J Polderman-Tijmes; Peter A Jekel; Christopher Williams; Gjalt Wybenga; Dick B Janssen; Bauke W Dijkstra
Acetobacter turbidans alpha-amino acid ester hydrolase: how a single mutation improves an antibiotic-producing enzyme.
The Journal of biological chemistry 2006;281(9):5804-10.
2006: Melloney J Dröge; Ykelien L Boersma; Gertie van Pouderoyen; Titia E Vrenken; Carsten J Rüggeberg; Manfred T Reetz; Bauke W Dijkstra; Wim J Quax
Directed evolution of Bacillus subtilis lipase A by use of enantiomeric phosphonate inhibitors: crystal structures and phage display selection.
Chembiochem : a European journal of chemical biology 2006;7(1):149-57.
2005: Karin E Van Straaten; Bauke W Dijkstra; Waldemar Vollmer; Andy-Mark W H Thunnissen
Crystal structure of MltA from Escherichia coli reveals a unique lytic transglycosylase fold.
Journal of molecular biology 2005;352(5):1068-80.
2005: René M de Jong; Jan J W Tiesinga; Alessandra Villa; Lixia Tang; Dick B Janssen; Bauke W Dijkstra
Structural basis for the enantioselectivity of an epoxide ring opening reaction catalyzed by halo alcohol dehalogenase HheC.
Journal of the American Chemical Society 2005;127(38):13338-43.
2005: Sharmini Alagaratnam; Gertie van Pouderoyen; Tjaard Pijning; Bauke W Dijkstra; Davide Cavazzini; Gian Luigi Rossi; Walter M A M van Dongen; Carlo P M van Mierlo; Willem J H van Berkel; Gerard W Canters
A crystallographic study of Cys69Ala flavodoxin II from Azotobacter vinelandii: structural determinants of redox potential.
Protein science : a publication of the Protein Society 2005;14(9):2284-95.
2005: Lixia Tang; Daniel E Torres Pazmiño; Marco W Fraaije; René M de Jong; Bauke W Dijkstra; Dick B Janssen
Improved catalytic properties of halohydrin dehalogenase by modification of the halide-binding site.
Biochemistry 2005;44(17):6609-18.
2005: Thomas R M Barends; René M de Jong; Karin E Van Straaten; Andy-Mark W H Thunnissen; Bauke W Dijkstra
Escherichia coli MltA: MAD phasing and refinement of a tetartohedrally twinned protein crystal structure.
Acta crystallographica. Section D, Biological crystallography 2005;61(Pt 5):613-21.
2005: Hiromi Yoshida; Charles Hensgens; Jan-Metske van der Laan; John D Sutherland; Darren J Hart; Bauke W Dijkstra
An approach to prevent aggregation during the purification and crystallization of wild type acyl coenzyme A: isopenicillin N acyltransferase from Penicillium chrysogenum.
Protein expression and purification 2005;41(1):61-7.
2004: Thomas R M Barends; Hiromi Yoshida; Bauke W Dijkstra
Three-dimensional structures of enzymes useful for beta-lactam antibiotic production.
Current opinion in biotechnology 2004;15(4):356-63.
2004: Wynand B L Alkema; Charles Hensgens; Harm J Snijder; Evelien Keizer; Bauke W Dijkstra; Dick B Janssen
Structural and kinetic studies on ligand binding in wild-type and active-site mutants of penicillin acylase.
Protein engineering, design & selection : PEDS 2004;17(5):473-80.
2004: André van Eerde; Cyril Hamiaux; Javier Pérez; Claude Parsot; Bauke W Dijkstra
Structure of Spa15, a type III secretion chaperone from Shigella flexneri with broad specificity.
EMBO reports 2004;5(5):477-83.
2004: Karin E Van Straaten; Bauke W Dijkstra; Andy-Mark W H Thunnissen
Purification, crystallization and preliminary X-ray analysis of the lytic transglycosylase MltA from Escherichia coli.
Acta crystallographica. Section D, Biological crystallography 2004;60(Pt 4):758-60.
2004: René M de Jong; Wim Brugman; Gerrit J Poelarends; Christian P Whitman; Bauke W Dijkstra
The X-ray structure of trans-3-chloroacrylic acid dehalogenase reveals a novel hydration mechanism in the tautomerase superfamily.
The Journal of biological chemistry 2004;279(12):11546-52.
2004: Hans Leemhuis; Henriëtte J Rozeboom; Bauke W Dijkstra; Lubbert Dijkhuizen
Improved thermostability of bacillus circulans cyclodextrin glycosyltransferase by the introduction of a salt bridge.
Proteins 2004;54(1):128-34.
2003: René M de Jong; Bauke W Dijkstra
Structure and mechanism of bacterial dehalogenases: different ways to cleave a carbon-halogen bond.
Current opinion in structural biology 2003;13(6):722-30.
2003: Bauke W Dijkstra; Rowena G Matthews
Catalysis and regulation - from structure to function.
Current opinion in structural biology 2003;13(6):706-8.
2003: Thomas R M Barends; Bauke W Dijkstra
Oils used in microbatch crystallization do not remove a detergent from the drops they cover.
Acta crystallographica. Section D, Biological crystallography 2003;59(Pt 12):2345-7.
2003: Thomas R M Barends; Bauke W Dijkstra
Acetobacter turbidans alpha-amino acid ester hydrolase: merohedral twinning in P21 obscured by pseudo-translational NCS.
Acta crystallographica. Section D, Biological crystallography 2003;59(Pt 12):2237-41.
2003: Maria Fittipaldi; Roberto A Steiner; Michio Matsushita; Bauke W Dijkstra; Edgar J J Groenen; Martina Huber
Single-crystal EPR study at 95 GHz of the type 2 copper site of the inhibitor-bound quercetin 2,3-dioxygenase.
Biophysical journal 2003;85(6):4047-54.
2003: Gregory Verdon; Sonja-Verena Albers; Niels van Oosterwijk; Bauke W Dijkstra; Arnold J M Driessen; Andy-Mark W H Thunnissen
Formation of the productive ATP-Mg2+-bound dimer of GlcV, an ABC-ATPase from Sulfolobus solfataricus.
Journal of molecular biology 2003;334(2):255-67.
2003: Gertie van Pouderoyen; Harm J Snijder; Jacques A E Benen; Bauke W Dijkstra
Structural insights into the processivity of endopolygalacturonase I from Aspergillus niger.
FEBS letters 2003;554(3):462-6.
2003: René M de Jong; Jan J W Tiesinga; Henriëtte J Rozeboom; Kor H Kalk; Lixia Tang; Dick B Janssen; Bauke W Dijkstra
Structure and mechanism of a bacterial haloalcohol dehalogenase: a new variation of the short-chain dehydrogenase/reductase fold without an NAD(P)H binding site.
The EMBO journal 2003;22(19):4933-44.
2003: Fabrizia Fusetti; Tjaard Pijning; Kor H Kalk; Ebo Bos; Bauke W Dijkstra
Crystal structure and carbohydrate-binding properties of the human cartilage glycoprotein-39.
The Journal of biological chemistry 2003;278(39):37753-60.
2003: Hans Leemhuis; Karsten M Kragh; Bauke W Dijkstra; Lubbert Dijkhuizen
Engineering cyclodextrin glycosyltransferase into a starch hydrolase with a high exo-specificity.
Journal of biotechnology 2003;103(3):203-12.
2003: Gregory Verdon; Sonja-Verena Albers; Bauke W Dijkstra; Arnold J M Driessen; Andy-Mark W H Thunnissen
Crystal structures of the ATPase subunit of the glucose ABC transporter from Sulfolobus solfataricus: nucleotide-free and nucleotide-bound conformations.
Journal of molecular biology 2003;330(2):343-58.
2003: Hans Leemhuis; Henriëtte J Rozeboom; Maarten Wilbrink; Gert-Jan W Euverink; Bauke W Dijkstra; Lubbert Dijkhuizen
Conversion of cyclodextrin glycosyltransferase into a starch hydrolase by directed evolution: the role of alanine 230 in acceptor subsite +1.
Biochemistry 2003;42(24):7518-26.
2003: Thomas R M Barends; Jolanda J Polderman-Tijmes; Peter A Jekel; Charles Hensgens; Erik J de Vries; Dick B Janssen; Bauke W Dijkstra
The sequence and crystal structure of the alpha-amino acid ester hydrolase from Xanthomonas citri define a new family of beta-lactam antibiotic acylases.
The Journal of biological chemistry 2003;278(25):23076-84.
2003: Hans Leemhuis; Henriëtte J Rozeboom; Bauke W Dijkstra; Lubbert Dijkhuizen
The fully conserved Asp residue in conserved sequence region I of the alpha-amylase family is crucial for the catalytic site architecture and activity.
FEBS letters 2003;541(1-3):47-51.
2003: Harm J Snijder; P A Timmins; Kor H Kalk; Bauke W Dijkstra
Detergent organisation in crystals of monomeric outer membrane phospholipase A.
Journal of structural biology 2003;141(2):122-31.
2003: Thomas R M Barends; Charles Hensgens; Jolanda J Polderman-Tijmes; Peter A Jekel; Erik De Vries; Dick B Janssen; Bauke W Dijkstra
X-ray analysis of two antibiotic-synthesizing bacterial ester hydrolases: preliminary results.
Acta crystallographica. Section D, Biological crystallography 2003;59(Pt 1):158-60.
2003: Hans Leemhuis; Bauke W Dijkstra; Lubbert Dijkhuizen
Thermoanaerobacterium thermosulfurigenes cyclodextrin glycosyltransferase.
European journal of biochemistry / FEBS 2003;270(1):155-62.
2002: Roberto A Steiner; Kor H Kalk; Bauke W Dijkstra
Anaerobic enzyme.substrate structures provide insight into the reaction mechanism of the copper-dependent quercetin 2,3-dioxygenase.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(26):16625-30.
2002: Fabrizia Fusetti; Holger von Moeller; Douglas Houston; Henriëtte J Rozeboom; Bauke W Dijkstra; Rolf G Boot; johannes aerts; Daan M F van Aalten
Structure of human chitotriosidase. Implications for specific inhibitor design and function of mammalian chitinase-like lectins.
The Journal of biological chemistry 2002;277(28):25537-44.
2002: Roberto A Steiner; Wolfram Meyer-Klaucke; Bauke W Dijkstra
Functional analysis of the copper-dependent quercetin 2,3-dioxygenase. 2. X-ray absorption studies of native enzyme and anaerobic complexes with the substrates quercetin and myricetin.
Biochemistry 2002;41(25):7963-8.
2002: Roberto A Steiner; Ingeborg M Kooter; Bauke W Dijkstra
Functional analysis of the copper-dependent quercetin 2,3-dioxygenase. 1. Ligand-induced coordination changes probed by X-ray crystallography: inhibition, ordering effect, and mechanistic insights.
Biochemistry 2002;41(25):7955-62.
2002: Ingeborg M Kooter; Roberto A Steiner; Bauke W Dijkstra; Paula I van Noort; Maarten R Egmond; Martina Huber
EPR characterization of the mononuclear Cu-containing Aspergillus japonicus quercetin 2,3-dioxygenase reveals dramatic changes upon anaerobic binding of substrates.
European journal of biochemistry / FEBS 2002;269(12):2971-9.
2002: Roelie L Kingma; Harm J Snijder; Bauke W Dijkstra; Nick Dekker; Maarten R Egmond
Functional importance of calcium binding sites in outer membrane phospholipase A.
Biochimica et biophysica acta 2002;1561(2):230-7.
2002: Charles Hensgens; Els A Kroezinga; Bart A van Montfort; Jan-Metske van der Laan; John D Sutherland; Bauke W Dijkstra
Purification, crystallization and preliminary X-ray diffraction of Cys103Ala acyl coenzyme A: isopenicillin N acyltransferase from Penicillium chrysogenum.
Acta crystallographica. Section D, Biological crystallography 2002;58(Pt 4):716-8.
2002: Hans Leemhuis; Bauke W Dijkstra; Lubbert Dijkhuizen
Mutations converting cyclodextrin glycosyltransferase from a transglycosylase into a starch hydrolase.
FEBS letters 2002;514(2-3):189-92.
2002: Evert Bokma; Henriëtte J Rozeboom; Mark Sibbald; Bauke W Dijkstra; Jaap J Beintema
Expression and characterization of active site mutants of hevamine, a chitinase from the rubber tree Hevea brasiliensis.
European journal of biochemistry / FEBS 2002;269(3):893-901.
2002: Fabrizia Fusetti; Klaus H Schröter; Roberto A Steiner; Paula I van Noort; Tjaard Pijning; Henriëtte J Rozeboom; Kor H Kalk; Maarten R Egmond; Bauke W Dijkstra
Crystal structure of the copper-containing quercetin 2,3-dioxygenase from Aspergillus japonicus.
Structure (London, England : 1993) 2002;10(2):259-68.
2002: Gregory Verdon; Sonja-Verena Albers; Bauke W Dijkstra; Arnold J M Driessen; Andy-Mark W H Thunnissen
Purification, crystallization and preliminary X-ray diffraction analysis of an archaeal ABC-ATPase.
Acta crystallographica. Section D, Biological crystallography 2002;58(Pt 2):362-5.
2002: Arthur Oubrie; Henriëtte J Rozeboom; Kor H Kalk; Eric G Huizinga; Bauke W Dijkstra
Crystal structure of quinohemoprotein alcohol dehydrogenase from Comamonas testosteroni: structural basis for substrate oxidation and electron transfer.
The Journal of biological chemistry 2002;277(5):3727-32.
2002: Hans Leemhuis; Joost C M Uitdehaag; Henriëtte J Rozeboom; Bauke W Dijkstra; Lubbert Dijkhuizen
The remote substrate binding subsite -6 in cyclodextrin-glycosyltransferase controls the transferase activity of the enzyme via an induced-fit mechanism.
The Journal of biological chemistry 2002;277(2):1113-9.
2002: René M de Jong; Henriëtte J Rozeboom; Kor H Kalk; Lixia Tang; Dick B Janssen; Bauke W Dijkstra
Crystallization and preliminary X-ray analysis of an enantioselective halohydrin dehalogenase from Agrobacterium radiobacter AD1.
Acta crystallographica. Section D, Biological crystallography 2002;58(Pt 1):176-8.
2001: Bart A van der Veen; Hans Leemhuis; Slavko Kralj; Joost C M Uitdehaag; Bauke W Dijkstra; Lubbert Dijkhuizen
Hydrophobic amino acid residues in the acceptor binding site are main determinants for reaction mechanism and specificity of cyclodextrin-glycosyltransferase.
The Journal of biological chemistry 2001;276(48):44557-62.
2001: Arthur Oubrie; E G Huizinga; Henriëtte J Rozeboom; Kor H Kalk; G A de Jong; Johannis A Duine; Bauke W Dijkstra
Crystallization of quinohaemoprotein alcohol dehydrogenase from Comamonas testosteroni: crystals with unique optical properties.
Acta crystallographica. Section D, Biological crystallography 2001;57(Pt 11):1732-4.
2001: Harm J Snijder; J H Van Eerde; Roelie L Kingma; Kor H Kalk; Nick Dekker; Maarten R Egmond; Bauke W Dijkstra
Structural investigations of the active-site mutant Asn156Ala of outer membrane phospholipase A: function of the Asn-His interaction in the catalytic triad.
Protein science : a publication of the Protein Society 2001;10(10):1962-9.
2001: T Eggert; Gertie van Pouderoyen; Bauke W Dijkstra; Karl-Erich Jaeger
Lipolytic enzymes LipA and LipB from Bacillus subtilis differ in regulation of gene expression, biochemical properties, and three-dimensional structure.
FEBS letters 2001;502(3):89-92.
2001: Harm J Snijder; Roelie L Kingma; Kor H Kalk; Nick Dekker; Maarten R Egmond; Bauke W Dijkstra
Structural investigations of calcium binding and its role in activity and activation of outer membrane phospholipase A from Escherichia coli.
Journal of molecular biology 2001;309(2):477-89.
2001: Gertie van Pouderoyen; T Eggert; Karl-Erich Jaeger; Bauke W Dijkstra
The crystal structure of Bacillus subtilis lipase: a minimal alpha/beta hydrolase fold enzyme.
Journal of molecular biology 2001;309(1):215-26.
2001: Joost C M Uitdehaag; Bart A van der Veen; Lubbert Dijkhuizen; R Elber; Bauke W Dijkstra
Enzymatic circularization of a malto-octaose linear chain studied by stochastic reaction path calculations on cyclodextrin glycosyltransferase.
Proteins 2001;43(3):327-35.
2001: Roberto A Steiner; Henriëtte J Rozeboom; A de Vries; Kor H Kalk; Garib N Murshudov; K S Wilson; Bauke W Dijkstra
X-ray structure of bovine pancreatic phospholipase A2 at atomic resolution.
Acta crystallographica. Section D, Biological crystallography 2001;57(Pt 4):516-26.
2000: Joost C M Uitdehaag; Bauke W Dijkstra; Lubbert Dijkhuizen
Engineering of cyclodextrin glycosyltransferase reaction and product specificity.
Biochimica et biophysica acta 2000;1543(2):336-360.
2000: Wynand B L Alkema; Charles Hensgens; E H Kroezinga; Erik De Vries; René Floris; Jan-Metske van der Laan; Bauke W Dijkstra; Dick B Janssen
Characterization of the beta-lactam binding site of penicillin acylase of Escherichia coli by structural and site-directed mutagenesis studies.
Protein engineering 2000;13(12):857-63.
2000: Harm J Snijder; Bauke W Dijkstra
Bacterial phospholipase A: structure and function of an integral membrane phospholipase.
Biochimica et biophysica acta 2000;1488(1-2):91-101.
2000: M Nardini; D A Lang; K Liebeton; Karl-Erich Jaeger; Bauke W Dijkstra
Crystal structure of pseudomonas aeruginosa lipase in the open conformation. The prototype for family I.1 of bacterial lipases.
The Journal of biological chemistry 2000;275(40):31219-25.
2000: K Liebeton; A Zonta; K Schimossek; M Nardini; D Lang; Bauke W Dijkstra; Manfred T Reetz; Karl-Erich Jaeger
Directed evolution of an enantioselective lipase.
Chemistry & biology 2000;7(9):709-18.
2000: Roelie L Kingma; M Fragiathaki; Harm J Snijder; Bauke W Dijkstra; HM Verheij; Nick Dekker; Maarten R Egmond
Unusual catalytic triad of Escherichia coli outer membrane phospholipase A.
Biochemistry 2000;39(33):10017-22.
2000: Joost C M Uitdehaag; GJ van Alebeek; Bart A van der Veen; Lubbert Dijkhuizen; Bauke W Dijkstra
Structures of maltohexaose and maltoheptaose bound at the donor sites of cyclodextrin glycosyltransferase give insight into the mechanisms of transglycosylation activity and cyclodextrin size specificity.
Biochemistry 2000;39(26):7772-80.
2000: Arthur Oubrie; Bauke W Dijkstra
Structural requirements of pyrroloquinoline quinone dependent enzymatic reactions.
Protein science : a publication of the Protein Society 2000;9(7):1265-73.
2000: Bart A van der Veen; Joost C M Uitdehaag; Bauke W Dijkstra; Lubbert Dijkhuizen
The role of arginine 47 in the cyclization and coupling reactions of cyclodextrin glycosyltransferase from Bacillus circulans strain 251 implications for product inhibition and product specificity.
European journal of biochemistry / FEBS 2000;267(12):3432-41.
2000: Bart A van der Veen; Joost C M Uitdehaag; D Penninga; GJ van Alebeek; L M Smith; Bauke W Dijkstra; Lubbert Dijkhuizen
Rational design of cyclodextrin glycosyltransferase from Bacillus circulans strain 251 to increase alpha-cyclodextrin production.
Journal of molecular biology 2000;296(4):1027-38.
2000: EJ Van Asselt; Kor H Kalk; Bauke W Dijkstra
Crystallographic studies of the interactions of Escherichia coli lytic transglycosylase Slt35 with peptidoglycan.
Biochemistry 2000;39(8):1924-34.
2000: Bart A van der Veen; GJ van Alebeek; Joost C M Uitdehaag; Bauke W Dijkstra; Lubbert Dijkhuizen
The three transglycosylation reactions catalyzed by cyclodextrin glycosyltransferase from Bacillus circulans (strain 251) proceed via different kinetic mechanisms.
European journal of biochemistry / FEBS 2000;267(3):658-65.
1999: Joost C M Uitdehaag; Kor H Kalk; Bart A van der Veen; Lubbert Dijkhuizen; Bauke W Dijkstra
The cyclization mechanism of cyclodextrin glycosyltransferase (CGTase) as revealed by a gamma-cyclodextrin-CGTase complex at 1.8-A resolution.
The Journal of biological chemistry 1999;274(49):34868-76.
1999: M Nardini; Bauke W Dijkstra
Alpha/beta hydrolase fold enzymes: the family keeps growing.
Current opinion in structural biology 1999;9(6):732-7.
1999: IS Ridder; Henriëtte J Rozeboom; Kor H Kalk; Bauke W Dijkstra
Crystal structures of intermediates in the dehalogenation of haloalkanoates by L-2-haloacid dehalogenase.
The Journal of biological chemistry 1999;274(43):30672-8.
1999: Y van Santen; Jacques A E Benen; Klaus H Schröter; Kor H Kalk; S Armand; J Visser; Bauke W Dijkstra
1.68-A crystal structure of endopolygalacturonase II from Aspergillus niger and identification of active site residues by site-directed mutagenesis.
The Journal of biological chemistry 1999;274(43):30474-80.
1999: EJ Van Asselt; A J Dijkstra; Kor H Kalk; B Takacs; W Keck; Bauke W Dijkstra
Crystal structure of Escherichia coli lytic transglycosylase Slt35 reveals a lysozyme-like catalytic domain with an EF-hand.
Structure (London, England : 1993) 1999;7(10):1167-80.
1999: Harm J Snijder; I Ubarretxena-Belandia; Mieke Blaauw; Kor H Kalk; HM Verheij; Maarten R Egmond; Nick Dekker; Bauke W Dijkstra
Structural evidence for dimerization-regulated activation of an integral membrane phospholipase.
Nature 1999;401(6754):717-21.
1999: Arthur Oubrie; Henriëtte J Rozeboom; Bauke W Dijkstra
Active-site structure of the soluble quinoprotein glucose dehydrogenase complexed with methylhydrazine: a covalent cofactor-inhibitor complex.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(21):11787-91.
1999: Arthur Oubrie; Henriëtte J Rozeboom; Kor H Kalk; AJ Olsthoorn; Johannis A Duine; Bauke W Dijkstra
Structure and mechanism of soluble quinoprotein glucose dehydrogenase.
The EMBO journal 1999;18(19):5187-94.
1999: EJ Van Asselt; Bauke W Dijkstra
Binding of calcium in the EF-hand of Escherichia coli lytic transglycosylase Slt35 is important for stability.
FEBS letters 1999;458(3):429-35.
1999: Mariël G Pikkemaat; IS Ridder; Henriëtte J Rozeboom; Kor H Kalk; Bauke W Dijkstra; Dick B Janssen
Crystallographic and kinetic evidence of a collision complex formed during halide import in haloalkane dehalogenase.
Biochemistry 1999;38(37):12052-61.
1999: EJ Van Asselt; Andy-Mark W H Thunnissen; Bauke W Dijkstra
High resolution crystal structures of the Escherichia coli lytic transglycosylase Slt70 and its complex with a peptidoglycan fragment.
Journal of molecular biology 1999;291(4):877-98.
1999: IS Ridder; Henriëtte J Rozeboom; Bauke W Dijkstra
Haloalkane dehalogenase from Xanthobacter autotrophicus GJ10 refined at 1.15 A resolution.
Acta crystallographica. Section D, Biological crystallography 1999;55(Pt 7):1273-90.
1999: Arthur Oubrie; Henriëtte J Rozeboom; Kor H Kalk; Johannis A Duine; Bauke W Dijkstra
The 1.7 A crystal structure of the apo form of the soluble quinoprotein glucose dehydrogenase from Acinetobacter calcoaceticus reveals a novel internal conserved sequence repeat.
Journal of molecular biology 1999;289(2):319-33.
1999: M Nardini; IS Ridder; Henriëtte J Rozeboom; Kor H Kalk; Rick Rink; Dick B Janssen; Bauke W Dijkstra
The x-ray structure of epoxide hydrolase from Agrobacterium radiobacter AD1. An enzyme to detoxify harmful epoxides.
The Journal of biological chemistry 1999;274(21):14579-86.
1999: Joost C M Uitdehaag; R Mosi; Kor H Kalk; Bart A van der Veen; Lubbert Dijkhuizen; Stephen G Withers; Bauke W Dijkstra
X-ray structures along the reaction pathway of cyclodextrin glycosyltransferase elucidate catalysis in the alpha-amylase family.
Nature structural biology 1999;6(5):432-6.
1999: IS Ridder; Bauke W Dijkstra
Identification of the Mg2+-binding site in the P-type ATPase and phosphatase members of the HAD (haloacid dehalogenase) superfamily by structural similarity to the response regulator protein CheY.
The Biochemical journal 1999;339 ( Pt 2)():223-6.
1998: R Mosi; H Sham; Joost C M Uitdehaag; R Ruiterkamp; Bauke W Dijkstra; Stephen G Withers
Reassessment of acarbose as a transition state analogue inhibitor of cyclodextrin glycosyltransferase.
Biochemistry 1998;37(49):17192-8.
1998: GH Krooshof; IS Ridder; A W Tepper; G J Vos; Henriëtte J Rozeboom; Kor H Kalk; Bauke W Dijkstra; Dick B Janssen
Kinetic analysis and X-ray structure of haloalkane dehalogenase with a modified halide-binding site.
Biochemistry 1998;37(43):15013-23.
1998: RL van Montfort; Bauke W Dijkstra
The functional importance of structural differences between the mannitol-specific IIAmannitol and the regulatory IIAnitrogen.
Protein science : a publication of the Protein Society 1998;7(10):2210-6.
1998: D A Lang; Maurice Mannesse; GH De Haas; HM Verheij; Bauke W Dijkstra
Structural basis of the chiral selectivity of Pseudomonas cepacia lipase.
European journal of biochemistry / FEBS 1998;254(2):333-40.
1998: D Bordo; R L van Monfort; Tjaard Pijning; Kor H Kalk; J Reizer; MH Saier; Bauke W Dijkstra
The three-dimensional structure of the nitrogen regulatory protein IIANtr from Escherichia coli.
Journal of molecular biology 1998;279(1):245-55.
1998: RL van Montfort; Tjaard Pijning; Kor H Kalk; I Hangyi; M L Kouwijzer; George T Robillard; Bauke W Dijkstra
The structure of the Escherichia coli phosphotransferase IIAmannitol reveals a novel fold with two conformations of the active site.
Structure (London, England : 1993) 1998;6(3):377-88.
1998: RD Wind; Joost C M Uitdehaag; R M Buitelaar; Bauke W Dijkstra; Lubbert Dijkhuizen
Engineering of cyclodextrin product specificity and pH optima of the thermostable cyclodextrin glycosyltransferase from Thermoanaerobacterium thermosulfurigenes EM1.
The Journal of biological chemistry 1998;273(10):5771-9.
1998: U Krengel; Klaus H Schröter; H Hoier; A Arkema; Kor H Kalk; P Zimniak; Bauke W Dijkstra
Crystal structure of a murine alpha-class glutathione S-transferase involved in cellular defense against oxidative stress.
FEBS letters 1998;422(3):285-90.
1998: EJ Van Asselt; Anastassis Perraks; Kor H Kalk; Victor S Lamzin; Bauke W Dijkstra
Accelerated X-ray structure elucidation of a 36 kDa muramidase/transglycosylase using wARP.
Acta crystallographica. Section D, Biological crystallography 1998;54(Pt 1):58-73.
1997: IS Ridder; Henriëtte J Rozeboom; Kor H Kalk; Dick B Janssen; Bauke W Dijkstra
Three-dimensional structure of L-2-haloacid dehalogenase from Xanthobacter autotrophicus GJ10 complexed with the substrate-analogue formate.
The Journal of biological chemistry 1997;272(52):33015-22.
1997: R Lapatto; U Krengel; H A Schreuder; A Arkema; Bert de Boer; Kor H Kalk; W G Hol; PD Grootenhuis; JW Mulders; R Dijkema; H J Theunissen; Bauke W Dijkstra
X-ray structure of antistasin at 1.9 A resolution and its modelled complex with blood coagulation factor Xa.
The EMBO journal 1997;16(17):5151-61.
1997: R Mosi; Shouming He; Joost C M Uitdehaag; Bauke W Dijkstra; Stephen G Withers
Trapping and characterization of the reaction intermediate in cyclodextrin glycosyltransferase by use of activated substrates and a mutant enzyme.
Biochemistry 1997;36(32):9927-34.
1997: RL van Montfort; Tjaard Pijning; Kor H Kalk; J Reizer; MH Saier; M M Thunnissen; George T Robillard; Bauke W Dijkstra
The structure of an energy-coupling protein from bacteria, IIBcellobiose, reveals similarity to eukaryotic protein tyrosine phosphatases.
Structure (London, England : 1993) 1997;5(2):217-25.
1996: D Penninga; Bart A van der Veen; R M Knegtel; S A van Hijum; Henriëtte J Rozeboom; Kor H Kalk; Bauke W Dijkstra; Lubbert Dijkhuizen
The raw starch binding domain of cyclodextrin glycosyltransferase from Bacillus circulans strain 251.
The Journal of biological chemistry 1996;271(51):32777-84.
1996: U Krengel; Bauke W Dijkstra
Three-dimensional structure of Endo-1,4-beta-xylanase I from Aspergillus niger: molecular basis for its low pH optimum.
Journal of molecular biology 1996;263(1):70-8.
1996: J P Schanstra; IS Ridder; G J Heimeriks; Rick Rink; Gerrit J Poelarends; Kor H Kalk; Bauke W Dijkstra; Dick B Janssen
Kinetic characterization and X-ray structure of a mutant of haloalkane dehalogenase with higher catalytic activity and modified substrate range.
Biochemistry 1996;35(40):13186-95.
1996: A C Terwisscha van Scheltinga; Michael Hennig; Bauke W Dijkstra
The 1.8 A resolution structure of hevamine, a plant chitinase/lysozyme, and analysis of the conserved sequence and structure motifs of glycosyl hydrolase family 18.
Journal of molecular biology 1996;262(2):243-57.
1996: U Krengel; Henriëtte J Rozeboom; Kor H Kalk; Bauke W Dijkstra
Crystallization and preliminary crystallographic analysis of endo-1,4-beta-xyalanase I from Aspergillus niger.
Acta crystallographica. Section D, Biological crystallography 1996;52(Pt 3):571-6.
1996: B Strokopytov; R M Knegtel; D Penninga; Henriëtte J Rozeboom; Kor H Kalk; Lubbert Dijkhuizen; Bauke W Dijkstra
Structure of cyclodextrin glycosyltransferase complexed with a maltononaose inhibitor at 2.6 angstrom resolution. Implications for product specificity.
Biochemistry 1996;35(13):4241-9.
1996: A M Thunnissen; Bauke W Dijkstra
Cure for a crisis?
Nature structural biology 1996;3(3):218-21.
1996: R M Knegtel; R D Wind; Henriëtte J Rozeboom; Kor H Kalk; R M Buitelaar; Lubbert Dijkhuizen; Bauke W Dijkstra
Crystal structure at 2.3 A resolution and revised nucleotide sequence of the thermostable cyclodextrin glycosyltransferase from Thermonanaerobacterium thermosulfurigenes EM1.
Journal of molecular biology 1996;256(3):611-22.
1996: F Fusetti; Bauke W Dijkstra
Purification and light-scattering analysis of penicillin-binding protein 4 from Escherichia coli.
Microbial drug resistance (Larchmont, N.Y.) 1996;2(1):73-6.
1996: J M van der Laan; O Misset; L J Mulleners; G Gerritse; H N Scheffers; D J van Schouwen; Alexey Teplyakov; Bauke W Dijkstra
Structural and functional consequences of engineering the high alkaline serine protease PB92.
Advances in experimental medicine and biology 1996;379():203-18.
1995: R M Knegtel; B Strokopytov; D Penninga; O G Faber; Henriëtte J Rozeboom; Kor H Kalk; Lubbert Dijkhuizen; Bauke W Dijkstra
Crystallographic studies of the interaction of cyclodextrin glycosyltransferase from Bacillus circulans strain 251 with natural substrates and products.
The Journal of biological chemistry 1995;270(49):29256-64.
1995: A C Terwisscha van Scheltinga; S Armand; Kor H Kalk; A Isogai; Bernard Henrissat; Bauke W Dijkstra
Stereochemistry of chitin hydrolysis by a plant chitinase/lysozyme and X-ray structure of a complex with allosamidin: evidence for substrate assisted catalysis.
Biochemistry 1995;34(48):15619-23.
1995: IS Ridder; Henriëtte J Rozeboom; J Kingma; Dick B Janssen; Bauke W Dijkstra
Crystallization and preliminary X-ray analysis of L-2-haloacid dehalogenase from Xanthobacter autotrophicus GJ10.
Protein science : a publication of the Protein Society 1995;4(12):2619-20.
1995: Michael Hennig; Johan N Jansonius; A C Terwisscha van Scheltinga; Bauke W Dijkstra; B Schlesier
Crystal structure of concanavalin B at 1.65 A resolution. An "inactivated" chitinase from seeds of Canavalia ensiformis.
Journal of molecular biology 1995;254(2):237-46.
1995: A M Thunnissen; Henriëtte J Rozeboom; Kor H Kalk; Bauke W Dijkstra
Structure of the 70-kDa soluble lytic transglycosylase complexed with bulgecin A. Implications for the enzymatic mechanism.
Biochemistry 1995;34(39):12729-37.
1995: Mieke Blaauw; Nick Dekker; HM Verheij; Kor H Kalk; Bauke W Dijkstra
Crystallization and preliminary X-ray analysis of outer membrane phospholipase A from Escherichia coli.
FEBS letters 1995;373(1):10-2.
1995: A M Thunnissen; N W Isaacs; Bauke W Dijkstra
The catalytic domain of a bacterial lytic transglycosylase defines a novel class of lysozymes.
Proteins 1995;22(3):245-58.
1995: M M Thunnissen; F Fusetti; B de Boer; Bauke W Dijkstra
Purification, crystallisation and preliminary X-ray analysis of penicillin binding protein 4 from Escherichia coli, a protein related to class A beta-lactamases.
Journal of molecular biology 1995;247(2):149-53.
1995: D Penninga; B Strokopytov; Henriëtte J Rozeboom; C L Lawson; Bauke W Dijkstra; J Bergsma; Lubbert Dijkhuizen
Site-directed mutations in tyrosine 195 of cyclodextrin glycosyltransferase from Bacillus circulans strain 251 affect activity and product specificity.
Biochemistry 1995;34(10):3368-76.
1995: S Ransac; Mieke Blaauw; Bauke W Dijkstra; A T Slotboom; Jan-Willem P Boots; HM Verheij
Crystallization and preliminary X-ray analysis of a lipase from Staphylococcus hyicus.
Journal of structural biology 1995;114(2):153-5.
1995: B Strokopytov; D Penninga; Henriëtte J Rozeboom; Kor H Kalk; Lubbert Dijkhuizen; Bauke W Dijkstra
X-ray structure of cyclodextrin glycosyltransferase complexed with acarbose. Implications for the catalytic mechanism of glycosidases.
Biochemistry 1995;34(7):2234-40.
1994: A C Terwisscha van Scheltinga; Kor H Kalk; Jaap J Beintema; Bauke W Dijkstra
Crystal structures of hevamine, a plant defence protein with chitinase and lysozyme activity, and its complex with an inhibitor.
Structure (London, England : 1993) 1994;2(12):1181-9.
1994: Bauke W Dijkstra; A M Thunnissen
'Holy' proteins. II: The soluble lytic transglycosylase.
Current opinion in structural biology 1994;4(6):810-3.
1994: K H Schröter; A Arkema; H C Kester; J Visser; Bauke W Dijkstra
Crystallization and preliminary crystallographic characterization of endo-polygalacturonase II from Aspergillus niger.
Journal of molecular biology 1994;243(2):351-2.
1994: Karl-Erich Jaeger; S Ransac; Bauke W Dijkstra; C Colson; M van Heuvel; O Misset
Bacterial lipases.
FEMS microbiology reviews 1994;15(1):29-63.
1994: R L van Montfort; Tjaard Pijning; Kor H Kalk; Gea K Schuurman-Wolters; J Reizer; MH Saier; George T Robillard; Bauke W Dijkstra
Crystallization of enzyme IIB of the cellobiose-specific phosphotransferase system of Escherichia coli.
Journal of molecular biology 1994;239(4):588-90.
1994: S Ransac; Mieke Blaauw; E Lesuisse; K Schanck; C Colson; Bauke W Dijkstra
Crystallization and preliminary X-ray analysis of a lipase from Bacillus subtilis.
Journal of molecular biology 1994;238(5):857-9.
1994: A M Thunnissen; Ate Dijkstra; Kor H Kalk; Henriëtte J Rozeboom; H Engel; W Keck; Bauke W Dijkstra
Doughnut-shaped structure of a bacterial muramidase revealed by X-ray crystallography.
Nature 1994;367(6465):750-3.
1994: C L Lawson; R van Montfort; B Strokopytov; Henriëtte J Rozeboom; Kor H Kalk; G E de Vries; D Penninga; Lubbert Dijkhuizen; Bauke W Dijkstra
Nucleotide sequence and X-ray structure of cyclodextrin glycosyltransferase from Bacillus circulans strain 251 in a maltose-dependent crystal form.
Journal of molecular biology 1994;236(2):590-600.
1993: Karl-Erich Jaeger; S Ransac; H B Koch; Francine Ferrato; Bauke W Dijkstra
Topological characterization and modeling of the 3D structure of lipase from Pseudomonas aeruginosa.
FEBS letters 1993;332(1-2):143-9.
1993: K H Verschueren; J Kingma; Henriëtte J Rozeboom; Kor H Kalk; Dick B Janssen; Bauke W Dijkstra
Crystallographic and fluorescence studies of the interaction of haloalkane dehalogenase with halide ions. Studies with halide compounds reveal a halide binding site in the active site.
Biochemistry 1993;32(35):9031-7.
1993: K H Verschueren; S M Franken; Henriëtte J Rozeboom; Kor H Kalk; Bauke W Dijkstra
Refined X-ray structures of haloalkane dehalogenase at pH 6.2 and pH 8.2 and implications for the reaction mechanism.
Journal of molecular biology 1993;232(3):856-72.
1993: M M Thunnissen; P A Franken; G H de Haas; J Drenth; Kor H Kalk; HM Verheij; Bauke W Dijkstra
Crystal structure of a porcine pancreatic phospholipase A2 mutant. A large conformational change caused by the F63V point mutation.
Journal of molecular biology 1993;232(3):839-55.
1993: K H Verschueren; F Seljée; Henriëtte J Rozeboom; Kor H Kalk; Bauke W Dijkstra
Crystallographic analysis of the catalytic mechanism of haloalkane dehalogenase.
Nature 1993;363(6431):693-8.
1993: K H Verschueren; S M Franken; Henriëtte J Rozeboom; Kor H Kalk; Bauke W Dijkstra
Non-covalent binding of the heavy atom compound [Au(CN)2]- at the halide binding site of haloalkane dehalogenase from Xanthobacter autotrophicus GJ10.
FEBS letters 1993;323(3):267-70.
1993: U Neumann; Jan Hofsteenge; A H Arkema; Bauke W Dijkstra
Crystallization of porcine liver ribonuclease inhibitor a member of the family of proteins containing leucine-rich repeats.
Journal of molecular biology 1993;231(2):505-8.
1993: J M van der Laan; Alexey Teplyakov; A A Lammers; Bauke W Dijkstra
Preliminary X-ray study of naproxen esterase from Bacillus subtilis.
Journal of molecular biology 1993;230(2):681-3.
1992: L A Lammers; Bauke W Dijkstra; R P van Weeghel; Hendri H Pas; George T Robillard
Crystallization of the A-domain of the mannitol transport protein enzyme IImtl.
Journal of molecular biology 1992;228(1):310-2.
1992: M M Thunnissen; P A Franken; G H de Haas; J Drenth; Kor H Kalk; HM Verheij; Bauke W Dijkstra
Site-directed mutagenesis and X-ray crystallography of two phospholipase A2 mutants: Y52F and Y73F.
Protein engineering 1992;5(7):597-603.
1992: Alexey Teplyakov; J M van der Laan; A A Lammers; H Kelders; Kor H Kalk; O Misset; L J Mulleners; Bauke W Dijkstra
Protein engineering of the high-alkaline serine protease PB92 from Bacillus alcalophilus: functional and structural consequences of mutation at the S4 substrate binding pocket.
Protein engineering 1992;5(5):413-20.
1992: J M van der Laan; Alexey Teplyakov; H Kelders; Kor H Kalk; O Misset; L J Mulleners; Bauke W Dijkstra
Crystal structure of the high-alkaline serine protease PB92 from Bacillus alcalophilus.
Protein engineering 1992;5(5):405-11.
1991: S M Franken; Henriëtte J Rozeboom; Kor H Kalk; Bauke W Dijkstra
Crystal structure of haloalkane dehalogenase: an enzyme to detoxify halogenated alkanes.
The EMBO journal 1991;10(6):1297-302.
1990: M M Thunnissen; Kor H Kalk; J Drenth; Bauke W Dijkstra
Structure of an engineered porcine phospholipase A2 with enhanced activity at 2.1 A resolution. Comparison with the wild-type porcine and Crotalus atrox phospholipase A2.
Journal of molecular biology 1990;216(2):425-39.
1990: M M Thunnissen; E Ab; Kor H Kalk; J Drenth; Bauke W Dijkstra; O P Kuipers; R Dijkman; G H de Haas; HM Verheij
X-ray structure of phospholipase A2 complexed with a substrate-derived inhibitor.
Nature 1990;347(6294):689-91.
1990: C L Lawson; J Bergsma; P M Bruinenberg; G de Vries; Lubbert Dijkhuizen; Bauke W Dijkstra
Maltodextrin-dependent crystallization of cyclomaltodextrin glucanotransferase from Bacillus circulans.
Journal of molecular biology 1990;214(4):807-9.
1990: Henriëtte J Rozeboom; Bauke W Dijkstra; H Engel; W Keck
Crystallization of the soluble lytic transglycosylase from Escherichia coli K12.
Journal of molecular biology 1990;212(4):557-9.
1990: Henriëtte J Rozeboom; A Budiani; Jaap J Beintema; Bauke W Dijkstra
Crystallization of hevamine, an enzyme with lysozyme/chitinase activity from Hevea brasiliensis latex.
Journal of molecular biology 1990;212(3):441-3.
1989: Oscar P Kuipers; M M Thunnissen; P de Geus; Bauke W Dijkstra; J Drenth; HM Verheij; G H de Haas
Enhanced activity and altered specificity of phospholipase A2 by deletion of a surface loop.
Science (New York, N.Y.) 1989;244(4900):82-5.
1989: Abraham Schierbeek; M B Swarte; Bauke W Dijkstra; Gert Vriend; Randy J Read; Wim G J Hol; J Drenth; C Betzel
X-ray structure of lipoamide dehydrogenase from Azotobacter vinelandii determined by a combination of molecular and isomorphous replacement techniques.
Journal of molecular biology 1989;206(2):365-79.
1989: Ida Van der klei; C L Lawson; Henriëtte J Rozeboom; Bauke W Dijkstra; Marten Veenhuis; W Harder; Wim G J Hol
Use of electron microscopy in the examination of lattice defects in crystals of alcohol oxidase.
FEBS letters 1989;244(1):213-6.
1988: B Hazes; Bauke W Dijkstra
Model building of disulfide bonds in proteins with known three-dimensional structure.
Protein engineering 1988;2(2):119-25.
1988: Henriëtte J Rozeboom; J Kingma; Dick B Janssen; Bauke W Dijkstra
Crystallization of haloalkane dehalogenase from Xanthobacter autotrophicus GJ10.
Journal of molecular biology 1988;200(3):611-2.
1988: R Renetseder; Bauke W Dijkstra; K Huizinga; Kor H Kalk; J Drenth
Crystal structure of bovine pancreatic phospholipase A2 covalently inhibited by p-bromo-phenacyl-bromide.
Journal of molecular biology 1988;200(1):181-8.
1985: R Renetseder; S Brunie; Bauke W Dijkstra; J Drenth; P B Sigler
A comparison of the crystal structures of phospholipase A2 from bovine pancreas and Crotalus atrox venom.
The Journal of biological chemistry 1985;260(21):11627-34.
1983: Bauke W Dijkstra; R Renetseder; Kor H Kalk; W G Hol; J Drenth
Structure of porcine pancreatic phospholipase A2 at 2.6 A resolution and comparison with bovine phospholipase A2.
Journal of molecular biology 1983;168(1):163-79.