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Kottarappat Dileepan

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Donald D Smith; Daniel J Stechschulte; Xiaoyu Tan; Ossama Tawfik; Vineesh V Raveendran; Kottarappat N Dileepan
Mast cell deficiency attenuates progression of atherosclerosis and hepatic steatosis in apolipoprotein E-null mice.
Damandeep S Walia; Jianping Zhou; Vineesh V Raveendran; Mukut Sharma; Ram Sharma; Daniel J Stechschulte; Kottarappat N Dileepan
Human mast cells (HMC-1 5C6) enhance interleukin-6 production by quiescent and lipopolysaccharide-stimulated human coronary artery endothelial cells.
Vineesh V Raveendran; Xiaoyu Tan; Matthew E Sweeney; Beth Levant; Joyce Slusser; Daniel J Stechschulte; Kottarappat N Dileepan
Lipopolysaccharide induces H1 receptor expression and enhances histamine responsiveness in human coronary artery endothelial cells.

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All Publications

2012: Donald D Smith; Daniel J Stechschulte; Xiaoyu Tan; Ossama Tawfik; Vineesh V Raveendran; Kottarappat N Dileepan
Mast cell deficiency attenuates progression of atherosclerosis and hepatic steatosis in apolipoprotein E-null mice.
American journal of physiology. Heart and circulatory physiology 2012;302(12):H2612-21.
2012: Damandeep S Walia; Jianping Zhou; Vineesh V Raveendran; Mukut Sharma; Ram Sharma; Daniel J Stechschulte; Kottarappat N Dileepan
Human mast cells (HMC-1 5C6) enhance interleukin-6 production by quiescent and lipopolysaccharide-stimulated human coronary artery endothelial cells.
Mediators of inflammation 2012;2012():274347.
2011: Vineesh V Raveendran; Xiaoyu Tan; Matthew E Sweeney; Beth Levant; Joyce Slusser; Daniel J Stechschulte; Kottarappat N Dileepan
Lipopolysaccharide induces H1 receptor expression and enhances histamine responsiveness in human coronary artery endothelial cells.
Immunology 2011;132(4):578-88.
2011: X Tan; E M Poulose; V V Raveendran; Bao Ting Zhu; Daniel J Stechschulte; Kottarappat N Dileepan
Regulation of the expression of cyclooxygenases and production of prostaglandin I₂ and E₂ in human coronary artery endothelial cells by curcumin.
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 2011;62(1):21-8.
2010: D D Smith; X Tan; Ossama Tawfik; G Milne; Daniel J Stechschulte; Kottarappat N Dileepan
Increased aortic atherosclerotic plaque development in female apolipoprotein E-null mice is associated with elevated thromboxane A2 and decreased prostacyclin production.
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 2010;61(3):309-16.
2007: Xiaoyu Tan; Suzanne Essengue; Jaya Talreja; Jeff Reese; Daniel J Stechschulte; Kottarappat N Dileepan
Histamine directly and synergistically with lipopolysaccharide stimulates cyclooxygenase-2 expression and prostaglandin I(2) and E(2) production in human coronary artery endothelial cells.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(11):7899-906.
2007: Ram Sharma; Vidudala Prasad; Ellen T McCarthy; Virginia J Savin; Kottarappat N Dileepan; Daniel J Stechschulte; Elias A Lianos; Thomas B Wiegmann; Mukut Sharma
Chymase increases glomerular albumin permeability via protease-activated receptor-2.
Molecular and cellular biochemistry 2007;297(1-2):161-9.
2006: Timothy J Nickel; Mohammad H Kabir; Jaya Talreja; Daniel J Stechschulte; Kottarappat N Dileepan
Constitutive expression of functionally active protease-activated receptors 1 and 2 in human conjunctival epithelial cells.
Mediators of inflammation 2006;2006(3):61359.
2006: Kottarappat N Dileepan; Daniel J Stechschulte
Endothelial cell activation by mast cell mediators.
Methods in molecular biology (Clifton, N.J.) 2006;315():275-94.
2005: Jaya Talreja; Kavitha Dileepan; Sanjeev Puri; Mohammad H Kabir; David M Segal; Daniel J Stechschulte; Kottarappat N Dileepan
Human conjunctival epithelial cells lack lipopolysaccharide responsiveness due to deficient expression of MD2 but respond after interferon-gamma priming or soluble MD2 supplementation.
Inflammation 2005;29(4-6):170-81.
2004: Kottarappat N Dileepan; Thomas P Johnston; Yuai Li; Ossama Tawfik; Daniel J Stechschulte
Deranged aortic intima-media thickness, plasma triglycerides and granulopoiesis in Sl/Sl(d) mice.
Mediators of inflammation 2004;13(5-6):335-41.
2004: Jaya Talreja; Mohammad H Kabir; Michael B Filla; Daniel J Stechschulte; Kottarappat N Dileepan
Histamine induces Toll-like receptor 2 and 4 expression in endothelial cells and enhances sensitivity to Gram-positive and Gram-negative bacterial cell wall components.
Immunology 2004;113(2):224-33.
2004: Margaret N Kennedy; Gregory E D Mullen; Cynthia A Leifer; ChangWoo Lee; Alessandra Mazzoni; Kottarappat N Dileepan; David M Segal
A complex of soluble MD-2 and lipopolysaccharide serves as an activating ligand for Toll-like receptor 4.
The Journal of biological chemistry 2004;279(33):34698-704.
2003: Thomas P Johnston; Yuai Li; Ahmed S Jamal; Daniel J Stechschulte; Kottarappat N Dileepan
Poloxamer 407-induced atherosclerosis in mice appears to be due to lipid derangements and not due to its direct effects on endothelial cells and macrophages.
Mediators of inflammation 2003;12(3):147-55.
2003: Luqi Chi; Lisa Stehno-Bittel; Irina Smirnova; Daniel J Stechschulte; Kottarappat N Dileepan
Signal transduction pathways in mast cell granule-mediated endothelial cell activation.
Mediators of inflammation 2003;12(2):79-87.
2001: Y Li; Luqi Chi; Daniel J Stechschulte; Kottarappat N Dileepan
Histamine-induced production of interleukin-6 and interleukin-8 by human coronary artery endothelial cells is enhanced by endotoxin and tumor necrosis factor-alpha.
Microvascular research 2001;61(3):253-62.
2001: Luqi Chi; Yuai Li; Lisa Stehno-Bittel; J Gao; David C Morrison; Daniel J Stechschulte; Kottarappat N Dileepan
Interleukin-6 production by endothelial cells via stimulation of protease-activated receptors is amplified by endotoxin and tumor necrosis factor-alpha.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2001;21(4):231-40.
2000: GW Wood; EH Hausmann; Rajani Choudhuri; Kottarappat N Dileepan
Expression and regulation of histidine decarboxylase mRNA expression in the uterus during pregnancy in the mouse.
Cytokine 2000;12(6):622-9.
2000: A B Jehle; Yuai Li; AC Stechschulte; Daniel J Stechschulte; Kottarappat N Dileepan
Endotoxin and mast cell granule proteases synergistically activate human coronary artery endothelial cells to generate interleukin-6 and interleukin-8.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2000;20(4):361-8.
1998: Bibhash C Paria; N Das; Sanjoy K Das; Xuemei Zhao; Kottarappat N Dileepan; Sudhansu K Dey
Histidine decarboxylase gene in the mouse uterus is regulated by progesterone and correlates with uterine differentiation for blastocyst implantation.
Endocrinology 1998;139(9):3958-66.
1998: Ellen T McCarthy; Ram Sharma; Mukut Sharma; JZ Li; XL Ge; Kottarappat N Dileepan; Virginia J Savin
TNF-alpha increases albumin permeability of isolated rat glomeruli through the generation of superoxide.
Journal of the American Society of Nephrology : JASN 1998;9(3):433-8.
1998: N Ito; Yuai Li; T Suzuki; Daniel J Stechschulte; Kottarappat N Dileepan
Transient degradation of NF-kappaB proteins in macrophages after interaction with mast cell granules.
Mediators of inflammation 1998;7(6):397-407.
1998: Yuai Li; T D Nguyen; AC Stechschulte; Daniel J Stechschulte; Kottarappat N Dileepan
Effect of mast cell granules on the gene expression of nitric oxide synthase and tumour necrosis factor-alpha in macrophages.
Mediators of inflammation 1998;7(5):355-61.
1997: Yuai Li; AC Stechschulte; DD Smith; Herbert B Lindsley; Daniel J Stechschulte; Kottarappat N Dileepan
Mast cell granules potentiate endotoxin-induced interleukin-6 production by endothelial cells.
Journal of leukocyte biology 1997;62(2):211-6.
1997: P J Rohan; Daniel J Stechschulte; Y Li; Kottarappat N Dileepan
Macrophage function in mice with a mutation at the microphthalmia (mi) locus.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 1997;215(3):269-74.
1995: Yuai Li; N Ito; T Suzuki; Daniel J Stechschulte; Kottarappat N Dileepan
Dexamethasone inhibits nitric oxide-mediated cytotoxicity via effects on both macrophages and target cells.
Immunopharmacology 1995;30(2):177-86.
1995: Kottarappat N Dileepan; J C Page; Yuai Li; Daniel J Stechschulte
Direct activation of murine peritoneal macrophages for nitric oxide production and tumor cell killing by interferon-gamma.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 1995;15(5):387-94.
1994: J Z Li; Ram Sharma; Kottarappat N Dileepan; Virginia J Savin
Polymorphonuclear leukocytes increase glomerular albumin permeability via hypohalous acid.
Kidney international 1994;46(4):1025-30.
1993: Kottarappat N Dileepan; Ram Sharma; Daniel J Stechschulte; Virginia J Savin
Effect of superoxide exposure on albumin permeability of isolated rat glomeruli.
The Journal of laboratory and clinical medicine 1993;121(6):797-804.
1993: Kottarappat N Dileepan; R B Lorsbach; Daniel J Stechschulte
Mast cell granules inhibit macrophage-mediated lysis of mastocytoma cells (P815) and nitric oxide production.
Journal of leukocyte biology 1993;53(4):446-53.
1991: K M Simpson; Kottarappat N Dileepan; Daniel J Stechschulte
Potentiation of antigen-induced mast cell activation by 1-34 bovine parathyroid hormone.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 1991;197(1):44-8.
1990: Daniel J Stechschulte; D C Morris; R L Jilka; D J Stechschulte; Kottarappat N Dileepan
Impaired gastric acid secretion in mast cell-deficient mice.
The American journal of physiology 1990;259(1 Pt 1):G41-7.
1989: Kottarappat N Dileepan; K M Simpson; Daniel J Stechschulte
Modulation of macrophage superoxide-induced cytochrome c reduction by mast cells.
The Journal of laboratory and clinical medicine 1989;113(5):577-85.
1989: A Yamada; Kottarappat N Dileepan; Daniel J Stechschulte; T Suzuki
Regulation of Fc gamma 2a receptor-mediated phagocytosis by a murine macrophage-like cell line, P388D1: involvement of casein kinase II activity associated with Fc gamma 2a receptor.
The Journal of molecular and cellular immunology : JMCI 1989;4(4):191-9; discussion 199-201.
1987: Daniel J Stechschulte; R Sharma; Kottarappat N Dileepan; K M Simpson; N Aggarwal; J Clancy; R L Jilka
Effect of the mi allele on mast cells, basophils, natural killer cells, and osteoclasts in C57Bl/6J mice.
Journal of cellular physiology 1987;132(3):565-70.