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Stefanie Dimmeler

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Jasmin Wagner; Andreas M Zeiher; Christian Besler; Stephan Fichtlscherer; Andrea Knau; Ulf Landmesser; Meliana Riwanto; Tino Röxe; Stefanie Dimmeler
Characterization of Levels and Cellular Transfer of Circulating Lipoprotein-Bound MicroRNAs.
Birgit Assmus; Stefanie Dimmeler; Walaa Khaled; Jens Klotsche; David M Leistner; Andreas Lutz; Florian H Seeger; Julia Steiner; Torsten Tonn; Dirk H Walter; Ina Ziegler; Andreas M Zeiher
Effect of shock wave-facilitated intracoronary cell therapy on LVEF in patients with chronic heart failure: the CELLWAVE randomized clinical trial.
Iva Nikolic; Chinmoy Patra; Karl H Plate; Michael K Schäfer; Kirsten Simon; Nevenka Dudvarski Stankovic; Serge C Thal; Khader Awwad; Jan Baumgart; Frank Bicker; Helene Braun; Emmanouil Chavakis; Stefanie Dimmeler; Johannes A Eble; Felix B Engel; Ingrid Fleming; Patrick N Harter; Benno Jungblut; Jeannette Meister; Michel Mittelbronn; Mirko H H Schmidt
EGFL7 ligates αvβ3 integrin to enhance vessel formation.

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2013: Jasmin Wagner; Andreas M Zeiher; Christian Besler; Stephan Fichtlscherer; Andrea Knau; Ulf Landmesser; Meliana Riwanto; Tino Röxe; Stefanie Dimmeler
Characterization of Levels and Cellular Transfer of Circulating Lipoprotein-Bound MicroRNAs.
Arteriosclerosis, thrombosis, and vascular biology 2013;33(6):1392-400.
2013: Birgit Assmus; Stefanie Dimmeler; Walaa Khaled; Jens Klotsche; David M Leistner; Andreas Lutz; Florian H Seeger; Julia Steiner; Torsten Tonn; Dirk H Walter; Ina Ziegler; Andreas M Zeiher
Effect of shock wave-facilitated intracoronary cell therapy on LVEF in patients with chronic heart failure: the CELLWAVE randomized clinical trial.
JAMA : the journal of the American Medical Association 2013;309(15):1622-31.
2013: Iva Nikolic; Chinmoy Patra; Karl H Plate; Michael K Schäfer; Kirsten Simon; Nevenka Dudvarski Stankovic; Serge C Thal; Khader Awwad; Jan Baumgart; Frank Bicker; Helene Braun; Emmanouil Chavakis; Stefanie Dimmeler; Johannes A Eble; Felix B Engel; Ingrid Fleming; Patrick N Harter; Benno Jungblut; Jeannette Meister; Michel Mittelbronn; Mirko H H Schmidt
EGFL7 ligates αvβ3 integrin to enhance vessel formation.
Blood 2013;121(15):3041-50.
2013: Timon Seeger; Andreas M Zeiher; Reinier A Boon; Ariane Fischer; Fatima Haffez; Ulrike Koehl; David M Leistner; Florian H Seeger; Stefanie Dimmeler
Immunosenescence-associated microRNAs in age and heart failure.
European journal of heart failure 2013;15(4):385-93.
2013: Reinier A Boon; Guillaume Carmona; Nathalie Didier; Peter Biliczki; Angelika Bonauer; Joachim R Ehrlich; Ariane Fischer; Zenawit Girmatsion; Heiko Hermeking; Susanne Heydt; Anton J G Horrevoets; Kazuma Iekushi; David Kaluza; Hugo A Katus; Stefanie Lechner; Oliver J Müller; Michael Potente; Timon Seeger; Karine Tréguer; Andreas M Zeiher; Stefanie Dimmeler
MicroRNA-34a regulates cardiac ageing and function.
Nature 2013;495(7439):107-10.
2013: David Kaluza; Jens Kroll; Yosif Manavski; Lothar Rössig; Carmen Urbich; Andreas M Zeiher; Arthur Zelent; Hellmut G Augustin; Jes-Niels Boeckel; Carmen Doebele; Sabine Gesierich; Stefanie Dimmeler
Histone deacetylase 9 promotes angiogenesis by targeting the antiangiogenic microRNA-17-92 cluster in endothelial cells.
Arteriosclerosis, thrombosis, and vascular biology 2013;33(3):533-43.
2013: Salvatore De Rosa; Stefanie Dimmeler; Stephan Fichtlscherer; Ulrich Fischer-Rasokat; Jörg Honold; Ralf Lehmann; Volker Schächinger; Florian H Seeger; Andreas M Zeiher; Birgit Assmus
Procedural safety and predictors of acute outcome of intracoronary administration of progenitor cells in 775 consecutive procedures performed for acute myocardial infarction or chronic heart failure.
Circulation. Cardiovascular interventions 2013;6(1):44-51.
2013: Stefanie Dimmeler; Pierluigi Nicotera
MicroRNAs in age-related diseases.
EMBO molecular medicine 2013;5(2):180-90.
2013: Christopher J Rhodes; Tino Roexe; Ralph Schermuly; Henning Tiede; Hilda Tsang; John Wharton; Beata Wojciak-Stothard; Andreas M Zeiher; Reinier A Boon; Anob Chakrabarti; Robin Condliffe; Stefanie Dimmeler; Charles A Elliot; Hossein A Ghofrani; J Simon R Gibbs; Luke S Howard; Les Huson; David G Kiely; Allan Lawrie; Martin R Wilkins
Reduced microRNA-150 is associated with poor survival in pulmonary arterial hypertension.
American journal of respiratory and critical care medicine 2013;187(3):294-302.
2013: Gian Paolo Fadini; Lisa Menegazzo; Nicol Poncina; Florian Seeger; Gaetano Thiene; Andreas Zeiher; Carlo Agostini; Mattia Albiero; Annalisa Angelini; Elisa Boscaro; Roberta Cappellari; Chiara Castellani; Stefanie Dimmeler; Angelo Avogaro
Stem cell compartmentalization in diabetes and high cardiovascular risk reveals the role of DPP-4 in diabetic stem cell mobilopathy.
Basic research in cardiology 2013;108(1):313.
2012: David M Leistner; Tino Röxe; Timon Seeger; Florian H Seeger; Birgit Assmus; Klaus Badenhoop; Stefanie Dimmeler; Ariane Fischer; Stefan Frantz; Jörg Honold; Kazuma Iekushi; Mahir Karakas; Jens Klotsche; Andreas M Zeiher
Elevated levels of the mediator of catabolic bone remodeling RANKL in the bone marrow environment link chronic heart failure with osteoporosis.
Circulation. Heart failure 2012;5(6):769-77.
2012: Reinier A Boon; Eduard Hergenreider; Stefanie Dimmeler
Atheroprotective mechanisms of shear stress-regulated microRNAs.
Thrombosis and haemostasis 2012;108(4):616-20.
2012: Stefan Rupp; Erhard Seifried; Torsten Tonn; Andreas M Zeiher; Jürgen Bauer; Halvard Bönig; Stefanie Dimmeler; Christian Jux; Dietmar Schranz
Intracoronary bone marrow cell application for terminal heart failure in children.
Cardiology in the young 2012;22(5):558-63.
2012: Florian H Seeger; Katharina Sommer; Andreas M Zeiher; Birgit Assmus; Emmanouil Chavakis; Ariane Fischer; Reinhard Henschler; Eduard Hergenreider; David M Leistner; Yosif Manavski; Marion Muhly-Reinholz; Tina Rasper; Stefanie Dimmeler
Heparin disrupts the CXCR4/SDF-1 axis and impairs the functional capacity of bone marrow-derived mononuclear cells used for cardiovascular repair.
Circulation research 2012;111(7):854-62.
2012: Marco Reis; Sascha Seidel; Makoto M Taketo; Sonja Thom; Nicole Ziegler; Jenny Zinke; Ernesto Bockamp; Cathrin J Czupalla; Kavi Devraj; Stefanie Dimmeler; Marcus Fruttiger; Rosario Heck; Jadranka Macas; Karl H Plate; Stefan Liebner
Endothelial Wnt/β-catenin signaling inhibits glioma angiogenesis and normalizes tumor blood vessels by inducing PDGF-B expression.
The Journal of experimental medicine 2012;209(9):1611-27.
2012: Birgit Assmus; Stefanie Dimmeler; Frank Grünwald; Kazuma Iekushi; Masayoshi Iwasaki; Masamichi Koyanagi; Wolfgang Tilman Kranert; Stefan Liebner; Tino Roexe; Volker Schächinger; Erhard Seifried; Torsten Tonn; Quanfu Xu; Andreas M Zeiher
Acute myocardial infarction activates progenitor cells and increases Wnt signalling in the bone marrow.
European heart journal 2012;33(15):1911-9.
2012: Caroline Cheng; Ihsan Chrifi; Renate de Jong; Wijnand K Den Dekker; Stefanie Dimmeler; Erik A L Biessen; Lau A J Blonden; Frank Bos; Petra E Bürgisser; Remco Haasdijk; Robert Herpers; Stefan Schulte-Merker; Dennie Tempel; Esther H M van de Kamp; Henricus J Duckers
Endothelial cell-specific FGD5 involvement in vascular pruning defines neovessel fate in mice.
Circulation 2012;125(25):3142-58.
2012: Timo Frömel; Bruce D Hammock; Jiong Hu; Benno Jungblut; Stefan Liebner; Rüdiger Popp; Caroline Trouvain; Eduardo Barbosa-Sicard; Stefanie Dimmeler; Ingrid Fleming
Soluble epoxide hydrolase regulates hematopoietic progenitor cell function via generation of fatty acid diols.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(25):9995-10000.
2012: Quanfu Xu; Andreas M Zeiher; Birgit Assmus; Reinier A Boon; Jessica Castillo; Ruxandra Farcas; Kazuma Iekushi; Yi-Gang Li; Yosif Manavski; Florian H Seeger; Stefanie Dimmeler
Micro-RNA-34a contributes to the impaired function of bone marrow-derived mononuclear cells from patients with cardiovascular disease.
Journal of the American College of Cardiology 2012;59(23):2107-17.
2012: Silvana Prokoph; Andrea Zieris; Emmanouil Chavakis; Stefanie Dimmeler; Uwe Freudenberg; Kandice R Levental; Carsten Werner
Sustained delivery of SDF-1α from heparin-based hydrogels to attract circulating pro-angiogenic cells.
Biomaterials 2012;33(19):4792-800.
2012: Katrin Schröder; Ajay M Shah; Norbert Weissmann; Min Zhang; Stefanie Dimmeler; Judith Kosowski; Christoph Kruse; Peter Luedike; U Ruth Michaelis; Anja Mieth; Rainer Pliquett; Sebastian Benkhoff; Ralf P Brandes
Nox4 is a protective reactive oxygen species generating vascular NADPH oxidase.
Circulation research 2012;110(9):1217-25.
2012: Kazuma Iekushi; Florian H Seeger; Andreas M Zeiher; Birgit Assmus; Stefanie Dimmeler
Regulation of cardiac microRNAs by bone marrow mononuclear cell therapy in myocardial infarction.
Circulation 2012;125(14):1765-73, S1-7.
2012: Eva-Marie Heinrich; Stefanie Dimmeler
MicroRNAs and stem cells: control of pluripotency, reprogramming, and lineage commitment.
Circulation research 2012;110(7):1014-22.
2012: Stefan Rupp; Jürgen Bauer; Stefanie Dimmeler; Stephan Fichtlscherer; Susanne von Gerlach; Andreas M Zeiher; Dietmar Schranz
Pressure overload leads to an increase of cardiac resident stem cells.
Basic research in cardiology 2012;107(2):252.
2012: Eduard Hergenreider; Susanne Heydt; Anton J G Horrevoets; Manuel Mayr; Margot P Scheffer; Karine Tréguer; Carmen Urbich; Xiaoke Yin; Andreas M Zeiher; Thomas Boettger; Reinier A Boon; Thomas Braun; Achilleas S Frangakis; Stefanie Dimmeler
Atheroprotective communication between endothelial cells and smooth muscle cells through miRNAs.
Nature cell biology 2012;14(3):249-56.
2012: Ulrich Fischer-Rasokat; Jörg Honold; Volker Schächinger; Florian H Seeger; Andreas M Zeiher; Stefanie Dimmeler; Stephan Fichtlscherer; Birgit Assmus
Early remodeling processes as predictors of diastolic function 5 years after reperfused acute myocardial infarction and intracoronary progenitor cell application.
Clinical research in cardiology : official journal of the German Cardiac Society 2012;101(3):209-16.
2012: Gian Paolo Fadini; Douglas Losordo; Stefanie Dimmeler
Critical reevaluation of endothelial progenitor cell phenotypes for therapeutic and diagnostic use.
Circulation research 2012;110(4):624-37.
2012: Soni Pullamsetti; Rajkumar Savai; Werner Seeger; Norbert Weissmann; Andreas M Zeiher; Angelika Bonauer; Bhola K Dahal; Stefanie Dimmeler; Carmen Doebele; Ariane Fischer; Hossein A Ghofrani; Friedrich Grimminger; Baktybek Kojonazarov; Ralph Theo Schermuly
Inhibition of microRNA-17 improves lung and heart function in experimental pulmonary hypertension.
American journal of respiratory and critical care medicine 2012;185(4):409-19.
2012: Carmen Urbich; Andreas M Zeiher; Katrin Bennewitz; Jes-Niels Boeckel; Angelika Bonauer; Reinier A Boon; Carmen Doebele; Ingrid Fleming; Timo Frömel; Eduard Hergenreider; David Kaluza; Andrea Knau; Jens Kroll; Stefanie Dimmeler
MicroRNA-27a/b controls endothelial cell repulsion and angiogenesis by targeting semaphorin 6A.
Blood 2012;119(6):1607-16.
2012: Saskia C A de Jager; Stefanie Dimmeler; Adriaan O Kraaijeveld; Patty J Nelemans; Mat Rousch; Theo J C van Berkel; Marja P van Dieijen-Visser; Michael Weber; Brenda W C Bongaerts; Kitty B J M Cleutjens; Erik A L Biessen
Chemokines CCL3/MIP1α, CCL5/RANTES and CCL18/PARC are independent risk predictors of short-term mortality in patients with acute coronary syndromes.
PloS one 2012;7(9):e45804.
2012: Jörg Honold; Ralf Lehmann; David M Leistner; Hans Martin; Volker Schachinger; Florian H Seeger; Andreas M Zeiher; Stefanie Dimmeler; Ulrich Fischer-Rasokat; Birgit Assmus
G-CSF Stimulation and Coronary Reinfusion of Mobilized Circulating Mononuclear Proangiogenic Cells in Patients With Chronic Ischemic Heart Disease:Five-Year Results of the TOPCARE-G-CSF Trial.
Cell transplantation 2012;21(11):2325-37.
2012: Julia E Weigand; Pascal Gellert; Jes-Niels Boeckel; Stefanie Dimmeler
Hypoxia-induced alternative splicing in endothelial cells.
PloS one 2012;7(8):e42697.
2012: Karine Tréguer; Angelika Bonauer; Eva-Marie Heinrich; Kisho Ohtani; Stefanie Dimmeler
Role of the microRNA-17-92 cluster in the endothelial differentiation of stem cells.
Journal of vascular research 2012;49(5):447-60.
2011: Stefanie Dimmeler
Cardiovascular disease review series.
EMBO molecular medicine 2011;3(12):697.
2011: Kisho Ohtani; Carmen Urbich; Georgios J Vlachojannis; Andreas M Zeiher; Jes-Niels Boeckel; Halvard Bonig; Ruxandra Farcas; Masamichi Koyanagi; Victor E Marquez; Stefanie Dimmeler
Epigenetic regulation of endothelial lineage committed genes in pro-angiogenic hematopoietic and endothelial progenitor cells.
Circulation research 2011;109(11):1219-29.
2011: Stephan Fichtlscherer; Andreas M Zeiher; Stefanie Dimmeler
Circulating microRNAs: biomarkers or mediators of cardiovascular diseases?
Arteriosclerosis, thrombosis, and vascular biology 2011;31(11):2383-90.
2011: Salvatore De Rosa; Stefanie Dimmeler; Stephan Fichtlscherer; Ralf Lehmann; Birgit Assmus; Andreas M Zeiher
Transcoronary concentration gradients of circulating microRNAs.
Circulation 2011;124(18):1936-44.
2011: Andreas Rolf; Volker Schächinger; Andreas M Zeiher; Birgit Assmus; Stefanie Dimmeler; Christian W Hamm; Helge Möllmann; Susanne Möllmann; Johannes Rixe; Thorsten Dill
Maladaptive hypertrophy after acute myocardial infarction positive effect of bone marrow-derived stem cell therapy on regional remodeling measured by cardiac MRI.
Clinical research in cardiology : official journal of the German Cardiac Society 2011;100(11):983-92.
2011: Reinier A Boon; Ralf P Brandes; Jeroen Essers; Ariane Fischer; Eduard Hergenreider; Susanne Heydt; Anton J G Horrevoets; Michele Pilato; Nadia Rosenthal; Sergio Sciacca; Timon Seeger; Paula van Heijningen; Manlio Vinciguerra; Andreas M Zeiher; Stefanie Dimmeler
MicroRNA-29 in aortic dilation: implications for aneurysm formation.
Circulation research 2011;109(10):1115-9.
2011: David Kaluza; Jens Kroll; Lothar Rössig; Edward Seto; Marc Tjwa; Hellmut G Augustin; Reinier A Boon; Stefanie Dimmeler; Sabine Gesierich; Eduard Hergenreider; Tso-Pang Yao; Andreas M Zeiher; Carmen Urbich
Class IIb HDAC6 regulates endothelial cell migration and angiogenesis by deacetylation of cortactin.
The EMBO journal 2011;30(20):4142-56.
2011: David M Leistner; Hans Martin; Volker Schächinger; Florian H Seeger; Carmen Urbich; Andreas M Zeiher; Iris Burck; Stefanie Dimmeler; Ulrich Fischer-Rasokat; Jörg Honold; Ralf Lehmann; Birgit Assmus
Transplantation of progenitor cells and regeneration enhancement in acute myocardial infarction (TOPCARE-AMI): final 5-year results suggest long-term safety and efficacy.
Clinical research in cardiology : official journal of the German Cardiac Society 2011;100(10):925-34.
2011: Stefanie Dimmeler; Douglas Losordo
Stem cells review series: an introduction.
Circulation research 2011;109(8):907-9.
2011: Emmanouil Chavakis; Stefanie Dimmeler
Homing of progenitor cells to ischemic tissues.
Antioxidants & redox signaling 2011;15(4):967-80.
2011: Reinier A Boon; Stefanie Dimmeler
MicroRNAs and aneurysm formation.
Trends in cardiovascular medicine 2011;21(6):172-7.
2011: Kisho Ohtani; Stefanie Dimmeler
Epigenetic regulation of cardiovascular differentiation.
Cardiovascular research 2011;90(3):404-12.
2011: Virginia Guarani; Gianluca Deflorian; Claudio A Franco; Marcus Krüger; Li-Kun Phng; Katie Bentley; Louise Toussaint; Franck Dequiedt; Raul Mostoslavsky; Mirko H H Schmidt; Barbara Zimmermann; Ralf P Brandes; Marina Mione; Christoph H Westphal; Thomas Braun; Andreas M Zeiher; Holger Gerhardt; Stefanie Dimmeler; Michael Potente
Acetylation-dependent regulation of endothelial Notch signalling by the SIRT1 deacetylase.
Nature 2011;473(7346):234-8.
2011: Gian Paolo Fadini; Mattia Albiero; Lisa Menegazzo; Elisa Boscaro; Saula Vigili de Kreutzenberg; Carlo Agostini; Anna Cabrelle; Gianni Binotto; Marcello Rattazzi; Elisa Bertacco; Roberta Bertorelle; Lorena Biasini; Monica Mion; Mario Plebani; Giulio Ceolotto; Annalisa Angelini; Chiara Castellani; Mirko Menegolo; Franco Grego; Stefanie Dimmeler; Florian Seeger; Andreas Zeiher; Antonio Tiengo; Angelo Avogaro
Widespread increase in myeloid calcifying cells contributes to ectopic vascular calcification in type 2 diabetes.
Circulation research 2011;108(9):1112-21.
2011: Stefanie Dimmeler
An interview with Stefanie Dimmeler, Chief Editor.
EMBO molecular medicine 2011;3(4):181-2.
2011: Masayoshi Iwasaki; Masamichi Koyanagi; Hans Kossmann; Nadejda Monsefi; Stefan Rupp; Janina Trauth; Patrick Paulus; Rebekka Goetz; Stefan Momma; Marc Tjwa; Kisho Ohtani; Reinhard Henschler; Dietmar Schranz; Giulio Cossu; Kai Zacharowski; Sven Martens; Andreas M Zeiher; Stefanie Dimmeler
Hepatocyte growth factor mobilizes non-bone marrow-derived circulating mesoangioblasts.
European heart journal 2011;32(5):627-36.
2011: Jes-Niels Boeckel; Virginia Guarani; Masamichi Koyanagi; Tino Roexe; Andreas Lengeling; Ralph Theo Schermuly; Pascal Gellert; Thomas Braun; Andreas Zeiher; Stefanie Dimmeler
Jumonji domain-containing protein 6 (Jmjd6) is required for angiogenic sprouting and regulates splicing of VEGF-receptor 1.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(8):3276-81.
2011: Dirk H Walter; Hans Krankenberg; Jörn O Balzer; Christoph Kalka; Iris Baumgartner; Michael Schlüter; Torsten Tonn; Florian Seeger; Stefanie Dimmeler; Edelgard Lindhoff-Last; Andreas M Zeiher
Intraarterial administration of bone marrow mononuclear cells in patients with critical limb ischemia: a randomized-start, placebo-controlled pilot trial (PROVASA).
Circulation. Cardiovascular interventions 2011;4(1):26-37.
2011: Carmen Urbich; Ayesha I De Souza; Lothar Rossig; Xiaoke Yin; Qiuru Xing; Marianna Prokopi; Ignat Drozdov; Marianne Steiner; Johannes Breuss; Qingbo Xu; Stefanie Dimmeler; Manuel Mayr
Proteomic characterization of human early pro-angiogenic cells.
Journal of molecular and cellular cardiology 2011;50(2):333-6.
2011: David M Leistner; Jörn Schmitt; Sylvia Palm; Jens Klotsche; Stephanie Estel; Agnes Fink; Carsten Israel; Birgit Assmus; Gabor Duray; Stefanie Dimmeler; Stefan H Hohnloser; Andreas M Zeiher
Intracoronary administration of bone marrow-derived mononuclear cells and arrhythmic events in patients with chronic heart failure.
European heart journal 2011;32(4):485-91.
2011: Reinier A Boon; Carmen Urbich; Ariane Fischer; Ruud D Fontijn; Florian H Seeger; Masamichi Koyanagi; Anton J G Horrevoets; Stefanie Dimmeler
Kruppel-like factor 2 improves neovascularization capacity of aged proangiogenic cells.
European heart journal 2011;32(3):371-7.
2011: Kisho Ohtani; Stefanie Dimmeler
Control of cardiovascular differentiation by microRNAs.
Basic research in cardiology 2011;106(1):5-11.
2011: Anna L Sander; Heike Jakob; Dirk Henrich; Maciej Powerski; Helen Witt; Stefanie Dimmeler; John Barker; Ingo Marzi; Johannes Frank
Systemic transplantation of progenitor cells accelerates wound epithelialization and neovascularization in the hairless mouse ear wound model.
The Journal of surgical research 2011;165(1):165-70.
2010: Alessia Orlandi; Emmanouil Chavakis; Florian H Seeger; Marc Tjwa; Andreas M Zeiher; Stefanie Dimmeler
Long-term diabetes impairs repopulation of hematopoietic progenitor cells and dysregulates the cytokine expression in the bone marrow microenvironment in mice.
Basic research in cardiology 2010;105(6):703-12.
2010: Stefanie Dimmeler; Andreas M Zeiher
Circulating microRNAs: novel biomarkers for cardiovascular diseases?
European heart journal 2010;31(22):2705-7.
2010: Matthias Hecker; Zbigniew Zaslona; Grazyna Kwapiszewska; Gero Niess; Anna Zakrzewicz; Eduard Hergenreider; Jochen Wilhelm; Leigh M Marsh; Daniel G Sedding; Walter Klepetko; Jürgen Lohmeyer; Stefanie Dimmeler; Werner Seeger; Norbert Weissmann; Ralph Theo Schermuly; Nikolaus Kneidinger; Oliver Eickelberg; Rory Morty
Dysregulation of the IL-13 receptor system: a novel pathomechanism in pulmonary arterial hypertension.
American journal of respiratory and critical care medicine 2010;182(6):805-18.
2010: Stephan Fichtlscherer; Salvatore De Rosa; Henrik Fox; Thomas Schwietz; Ariane Fischer; Christoph Liebetrau; Michael Weber; Christian W Hamm; Tino Röxe; Marga Müller-Ardogan; Angelika Bonauer; Andreas M Zeiher; Stefanie Dimmeler
Circulating microRNAs in patients with coronary artery disease.
Circulation research 2010;107(5):677-84.
2010: Angelika Bonauer; Reinier A Boon; Stefanie Dimmeler
Vascular microRNAs.
Current drug targets 2010;11(8):943-9.
2010: David Simper; Ursula Mayr; Carmen Urbich; Anna Zampetaki; Marianna Prokopi; ATHANASIOS DIDANGELOS; Angelika Saje; Michael Mueller; Ulrike Benbow; Andrew C Newby; Rolf Apweiler; Salman Rahman; Stefanie Dimmeler; Qingbo Xu; Manuel Mayr
Comparative proteomics profiling reveals role of smooth muscle progenitors in extracellular matrix production.
Arteriosclerosis, thrombosis, and vascular biology 2010;30(7):1325-32.
2010: Harald F Langer; Jürgen W von der Ruhr; Karin Daub; Tanja Schoenberger; Konstantinos Stellos; Andreas E May; Hannah Schnell; Alexandra Gauss; Ramona Hafner; Peter Lang; Michael Schumm; Hans-Jörg Bühring; Karin Klingel; Sabine Conrad; Martin Schaller; Marc van Zandvoort; Gundram Jung; Stefanie Dimmeler; Thomas Skutella; Meinrad Gawaz
Capture of endothelial progenitor cells by a bispecific protein/monoclonal antibody molecule induces reendothelialization of vascular lesions.
Journal of molecular medicine (Berlin, Germany) 2010;88(7):687-99.
2010: Caroline Schmidt-Lucke; Stephan Fichtlscherer; Lothar Rössig; Ulrike Kämper; Stefanie Dimmeler
Improvement of endothelial damage and regeneration indexes in patients with coronary artery disease after 4 weeks of statin therapy.
Atherosclerosis 2010;211(1):249-54.
2010: Carmen Doebele; Angelika Bonauer; Ariane Fischer; Alexander Scholz; Yvonne Reiss; Carmen Urbich; Wolf-Karsten Hofmann; Andreas M Zeiher; Stefanie Dimmeler
Members of the microRNA-17-92 cluster exhibit a cell-intrinsic antiangiogenic function in endothelial cells.
Blood 2010;115(23):4944-50.
2010: Stefanie Dimmeler
Regulation of bone marrow-derived vascular progenitor cell mobilization and maintenance.
Arteriosclerosis, thrombosis, and vascular biology 2010;30(6):1088-93.
2010: Chang-Hwan Yoon; Masamichi Koyanagi; Kazuma Iekushi; Florian H Seeger; Carmen Urbich; Andreas M Zeiher; Stefanie Dimmeler
Mechanism of improved cardiac function after bone marrow mononuclear cell therapy: role of cardiovascular lineage commitment.
Circulation 2010;121(18):2001-11.
2010: Gian Paolo Fadini; Elisa Boscaro; Saula Vigili de Kreutzenberg; Carlo Agostini; Florian Seeger; Stefanie Dimmeler; Andreas Zeiher; Antonio Tiengo; Angelo Avogaro
Time course and mechanisms of circulating progenitor cell reduction in the natural history of type 2 diabetes.
Diabetes care 2010;33(5):1097-102.
2010: Stefan Rupp; Andreas M Zeiher; Stefanie Dimmeler; Torsten Tonn; Juergen Bauer; Christian Jux; Hakan Akintuerk; Dietmar Schranz
A regenerative strategy for heart failure in hypoplastic left heart syndrome: intracoronary administration of autologous bone marrow-derived progenitor cells.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 2010;29(5):574-7.
2010: Florian H Seeger; Daniel Sedding; Alexander C Langheinrich; Judith Haendeler; Andreas M Zeiher; Stefanie Dimmeler
Inhibition of the p38 MAP kinase in vivo improves number and functional activity of vasculogenic cells and reduces atherosclerotic disease progression.
Basic research in cardiology 2010;105(3):389-97.
2010: Masamichi Koyanagi; Masayoshi Iwasaki; Stefan Rupp; Francesco Saverio Tedesco; Chang-Hwan Yoon; Jes-Niels Boeckel; Janina Trauth; Corina Schütz; Kisho Ohtani; Rebekka Goetz; Kazuma Iekushi; Philipp Bushoven; Stefan Momma; Christine Mummery; Robert Passier; Reinhard Henschler; Hakan Akintuerk; Dietmar Schranz; Carmen Urbich; Beatriz G Galvez; Giulio Cossu; Andreas M Zeiher; Stefanie Dimmeler
Sox2 transduction enhances cardiovascular repair capacity of blood-derived mesoangioblasts.
Circulation research 2010;106(7):1290-302.
2010: Birgit Assmus; Torsten Tonn; Florian H Seeger; Chang-Hwan Yoon; David Leistner; Jens Klotsche; Volker Schächinger; Erhard Seifried; Andreas M Zeiher; Stefanie Dimmeler
Red blood cell contamination of the final cell product impairs the efficacy of autologous bone marrow mononuclear cell therapy.
Journal of the American College of Cardiology 2010;55(13):1385-94.
2010: Jan Mersmann; Reinhard Berkels; Paula Zacharowski; Nguyen Tran; Alexander Koch; Kazuma Iekushi; Stefanie Dimmeler; tiago granja; Olaf Boehm; William C Claycomb; Kai Zacharowski
Preconditioning by toll-like receptor 2 agonist Pam3CSK4 reduces CXCL1-dependent leukocyte recruitment in murine myocardial ischemia/reperfusion injury.
Critical care medicine 2010;38(3):903-9.
2010: Emmanouil Chavakis; Masamichi Koyanagi; Stefanie Dimmeler
Enhancing the outcome of cell therapy for cardiac repair: progress from bench to bedside and back.
Circulation 2010;121(2):325-35.
2010: Caroline Schmidt-Lucke; Stephan Fichtlscherer; Alexandra Aicher; Carsten Tschöpe; Heinz-Peter Schultheiss; Andreas M Zeiher; Stefanie Dimmeler
Quantification of circulating endothelial progenitor cells using the modified ISHAGE protocol.
PloS one 2010;5(11):e13790.
2010: Gian Paolo Fadini; Shoichi Maruyama; Takenori Ozaki; Akihiko Taguchi; James Meigs; Stefanie Dimmeler; Andreas M Zeiher; Saula de Kreutzenberg; Angelo Avogaro; Georg Nickenig; Caroline Schmidt-Lucke; Nikos Werner
Circulating progenitor cell count for cardiovascular risk stratification: a pooled analysis.
PloS one 2010;5(7):e11488.
2010: Jens Minnerup; Florian H Seeger; Katharina Kuhnert; Kai Diederich; Matthias Schilling; Stefanie Dimmeler; Wolf-Rüdiger Schäbitz
Intracarotid administration of human bone marrow mononuclear cells in rat photothrombotic ischemia.
Experimental & translational stroke medicine 2010;2(1):3.
2010: Birgit Assmus; Andreas Rolf; Sandra Erbs; Albrecht Elsässer; Werner Haberbosch; Rainer Hambrecht; Harald Tillmanns; Jiangtao Yu; Roberto Corti; Detlef G Mathey; Christian W Hamm; Tim Süselbeck; Torsten Tonn; Stefanie Dimmeler; Thorsten Dill; Andreas M Zeiher; Volker Schächinger
Clinical outcome 2 years after intracoronary administration of bone marrow-derived progenitor cells in acute myocardial infarction.
Circulation. Heart failure 2010;3(1):89-96.
2009: Angelika Bonauer; Stefanie Dimmeler
The microRNA-17-92 cluster: still a miRacle?
Cell cycle (Georgetown, Tex.) 2009;8(23):3866-73.
2009: Giovanna Balconi; Ralf Lehmann; Fabio Fiordaliso; Birgit Assmus; Stefanie Dimmeler; Patrizio Sarto; Emanuele Carbonieri; Alessandra Gualco; Carlo Campana; Laura Angelici; Serge Masson; Salman Aa Mohammed; Elisabetta Dejana; Marco Gorini; Andreas M Zeiher; Roberto Latini
Levels of circulating pro-angiogenic cells predict cardiovascular outcomes in patients with chronic heart failure.
Journal of cardiac failure 2009;15(9):747-55.
2009: Florian H Seeger; Tina Rasper; Masamichi Koyanagi; Henrik Fox; Andreas M Zeiher; Stefanie Dimmeler
CXCR4 expression determines functional activity of bone marrow-derived mononuclear cells for therapeutic neovascularization in acute ischemia.
Arteriosclerosis, thrombosis, and vascular biology 2009;29(11):1802-9.
2009: Gian Paolo Fadini; Saula Vigili de Kreutzenberg; Carlo Agostini; Elisa Boscaro; Antonio Tiengo; Stefanie Dimmeler; Angelo Avogaro
Low CD34+ cell count and metabolic syndrome synergistically increase the risk of adverse outcomes.
Atherosclerosis 2009;207(1):213-9.
2009: Ioakim Spyridopoulos; Jedrzej Hoffmann; Alexandra Aicher; Tim H Brümmendorf; Hans W Doerr; Andreas M Zeiher; Stefanie Dimmeler
Accelerated telomere shortening in leukocyte subpopulations of patients with coronary heart disease: role of cytomegalovirus seropositivity.
Circulation 2009;120(14):1364-72.
2009: Volker Schächinger; Birgit Assmus; Sandra Erbs; Albrecht Elsässer; Werner Haberbosch; Rainer Hambrecht; Jiangtao Yu; Roberto Corti; Detlef G Mathey; Christian W Hamm; Torsten Tonn; Stefanie Dimmeler; Andreas M Zeiher
Intracoronary infusion of bone marrow-derived mononuclear cells abrogates adverse left ventricular remodelling post-acute myocardial infarction: insights from the reinfusion of enriched progenitor cells and infarct remodelling in acute myocardial infarction (REPAIR-AMI) trial.
European journal of heart failure 2009;11(10):973-9.
2009: Claudia Bearzi; Annarosa Leri; Francesco Lo Monaco; Marcello Rota; Arantxa Gonzalez; Toru Hosoda; Martino Pepe; Khaled Qanud; Caroline Ojaimi; Silvana Bardelli; D'Amario Domenico; David D'Alessandro; Robert Michler; Stefanie Dimmeler; Andreas M Zeiher; Konrad Urbanek; Thomas H Hintze; Jan Kajstura; Piero Anversa
Identification of a coronary vascular progenitor cell in the human heart.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(37):15885-90.
2009: Katrin Schröder; Andreas Kohnen; Alexandra Aicher; Elisa A Liehn; Tom Büchse; Stefan Stein; Christian Weber; Stefanie Dimmeler; Ralf P Brandes
NADPH oxidase Nox2 is required for hypoxia-induced mobilization of endothelial progenitor cells.
Circulation research 2009;105(6):537-44.
2009: Ulrich Fischer-Rasokat; Birgit Assmus; Florian H Seeger; Jörg Honold; David Leistner; Stephan Fichtlscherer; Volker Schächinger; Torsten Tonn; Hans Martin; Stefanie Dimmeler; Andreas M Zeiher
A pilot trial to assess potential effects of selective intracoronary bone marrow-derived progenitor cell infusion in patients with nonischemic dilated cardiomyopathy: final 1-year results of the transplantation of progenitor cells and functional regeneration enhancement pilot trial in patients with nonischemic dilated cardiomyopathy.
Circulation. Heart failure 2009;2(5):417-23.
2009: Thomas Braun; Stefanie Dimmeler
Breaking the silence: stimulating proliferation of adult cardiomyocytes.
Developmental cell 2009;17(2):151-3.
2009: Stefan Rupp; Jürgen Bauer; Torsten Tonn; Volker Schächinger; Stefanie Dimmeler; Andreas M Zeiher; Dietmar Schranz
Intracoronary administration of autologous bone marrow-derived progenitor cells in a critically ill two-yr-old child with dilated cardiomyopathy.
Pediatric transplantation 2009;13(5):620-3.
2009: Angelika Bonauer; Guillaume Carmona; Masayoshi Iwasaki; Marina Mione; Masamichi Koyanagi; Ariane Fischer; Jana Burchfield; Henrik Fox; Carmen Doebele; Kisho Ohtani; Emmanouil Chavakis; Michael Potente; Marc Tjwa; Carmen Urbich; Andreas M Zeiher; Stefanie Dimmeler
MicroRNA-92a controls angiogenesis and functional recovery of ischemic tissues in mice.
Science (New York, N.Y.) 2009;324(5935):1710-3.
2009: Judith Haendeler; Stefan Dröse; Nicole Büchner; Sascha Jakob; Joachim Altschmied; Christine Goy; Ioakim Spyridopoulos; Andreas M Zeiher; Ulrich Brandt; Stefanie Dimmeler
Mitochondrial telomerase reverse transcriptase binds to and protects mitochondrial DNA and function from damage.
Arteriosclerosis, thrombosis, and vascular biology 2009;29(6):929-35.
2009: Carmen Urbich; Lothar Rössig; David Kaluza; Michael Potente; Jes-Niels Boeckel; Andrea Knau; Florian Diehl; Jian-Guo Geng; Wolf-Karsten Hofmann; Andreas M Zeiher; Stefanie Dimmeler
HDAC5 is a repressor of angiogenesis and determines the angiogenic gene expression pattern of endothelial cells.
Blood 2009;113(22):5669-79.
2009: Jedrzej Hoffmann; Young Erben; Andreas M Zeiher; Stefanie Dimmeler; Ioakim Spyridopoulos
Telomere length-heterogeneity among myeloid cells is a predictor for chronological ageing.
Experimental gerontology 2009;44(5):363-6.
2009: Dörte Scharner; Lothar Rössig; Guillaume Carmona; Emmanouil Chavakis; Carmen Urbich; Ariane Fischer; Tae-Bong Kang; David Wallach; Yungping Jeffrey Chiang; Yonathan Lissanu Deribe; Ivan Dikic; Andreas M Zeiher; Stefanie Dimmeler
Caspase-8 is involved in neovascularization-promoting progenitor cell functions.
Arteriosclerosis, thrombosis, and vascular biology 2009;29(4):571-8.
2009: Thorsten Dill; Volker Schächinger; Andreas Rolf; Susanne Möllmann; Holger Thiele; Harald Tillmanns; Birgit Assmus; Stefanie Dimmeler; Andreas M Zeiher; Christian Hamm
Intracoronary administration of bone marrow-derived progenitor cells improves left ventricular function in patients at risk for adverse remodeling after acute ST-segment elevation myocardial infarction: results of the Reinfusion of Enriched Progenitor cells And Infarct Remodeling in Acute Myocardial Infarction study (REPAIR-AMI) cardiac magnetic resonance imaging substudy.
American heart journal 2009;157(3):541-7.
2009: Guillaume Carmona; Stephan Göttig; Alessia Orlandi; Jürgen Scheele; Tobias Bäuerle; Manfred Jugold; Fabian Kiessling; Reinhard Henschler; Andreas M Zeiher; Stefanie Dimmeler; Emmanouil Chavakis
Role of the small GTPase Rap1 for integrin activity regulation in endothelial cells and angiogenesis.
Blood 2009;113(2):488-97.
2009: Masamichi Koyanagi; Masayoshi Iwasaki; Judith Haendeler; Michael Leitges; Andreas M Zeiher; Stefanie Dimmeler
Wnt5a increases cardiac gene expressions of cultured human circulating progenitor cells via a PKC delta activation.
PloS one 2009;4(6):e5765.
2009: Alexandra Aicher; Christopher Heeschen; Susanne Feil; Franz Hofmann; Michael E Mendelsohn; Robert Feil; Stefanie Dimmeler
cGMP-dependent protein kinase I is crucial for angiogenesis and postnatal vasculogenesis.
PloS one 2009;4(3):e4879.
2009: Stefanie Dimmeler; Andreas M Zeiher
Cell therapy of acute myocardial infarction: open questions.
Cardiology 2009;113(3):155-60.
2008: Stefanie Dimmeler; Marc Tjwa
Better regenerative output after cellular input: healing hearts by combining basic fibroblast factor and cell-based therapy.
Journal of the American College of Cardiology 2008;52(23):1866-8.
2008: Thomas Ziebart; Chang-Hwan Yoon; Thomas Trepels; Astrid Wietelmann; Thomas Braun; Fabian Kiessling; Stefan Stein; Manuel Grez; Christian Ihling; Marion Muhly-Reinholz; Guillaume Carmona; Carmen Urbich; Andreas M Zeiher; Stefanie Dimmeler
Sustained persistence of transplanted proangiogenic cells contributes to neovascularization and cardiac function after ischemia.
Circulation research 2008;103(11):1327-34.
2008: Eun Young Choi; Emmanouil Chavakis; Marcus A Czabanka; Harald F Langer; Line Fraemohs; Matina Economopoulou; Ramendra K Kundu; Alessia Orlandi; Ying Yi Zheng; DaRue A Prieto; Christie M Ballantyne; Stephanie L Constant; William C Aird; Thalia Papayannopoulou; Carl G Gahmberg; Mark C Udey; Peter Vajkoczy; Thomas Quertermous; Stefanie Dimmeler; Christian Weber; Triantafyllos Chavakis
Del-1, an endogenous leukocyte-endothelial adhesion inhibitor, limits inflammatory cell recruitment.
Science (New York, N.Y.) 2008;322(5904):1101-4.
2008: Julien Dinkel; Soenke H Bartling; Jan Kuntz; Michael Grasruck; Annette Kopp-Schneider; Masayoshi Iwasaki; Stefanie Dimmeler; Rajiv Gupta; Wolfhard Semmler; Hans-Ulrich Kauczor; Fabian Kiessling
Intrinsic gating for small-animal computed tomography: a robust ECG-less paradigm for deriving cardiac phase information and functional imaging.
Circulation. Cardiovascular imaging 2008;1(3):235-43.
2008: Ioakim Spyridopoulos; Stephan Fichtlscherer; Rüdiger Popp; Stefan W Toennes; Beate Fisslthaler; Thomas Trepels; Alma Zernecke; Elisa A Liehn; Christian Weber; Andreas M Zeiher; Stefanie Dimmeler; Judith Haendeler
Caffeine enhances endothelial repair by an AMPK-dependent mechanism.
Arteriosclerosis, thrombosis, and vascular biology 2008;28(11):1967-74.
2008: Elisabeth Dernbach; Voahanginirina Randriamboavonjy; Ingrid Fleming; Andreas M Zeiher; Stefanie Dimmeler; Carmen Urbich
Impaired interaction of platelets with endothelial progenitor cells in patients with cardiovascular risk factors.
Basic research in cardiology 2008;103(6):572-81.
2008: Alexandra Aicher; Orit Kollet; Christopher Heeschen; Stefan Liebner; Carmen Urbich; Christian Ihling; Alessia Orlandi; Tsvee Lapidot; Andreas M Zeiher; Stefanie Dimmeler
The Wnt antagonist Dickkopf-1 mobilizes vasculogenic progenitor cells via activation of the bone marrow endosteal stem cell niche.
Circulation research 2008;103(8):796-803.
2008: Emmanouil Chavakis; Carmen Urbich; Stefanie Dimmeler
Homing and engraftment of progenitor cells: a prerequisite for cell therapy.
Journal of molecular and cellular cardiology 2008;45(4):514-22.
2008: Volker Schächinger; Alexandra Aicher; Natascha Döbert; Rainer Röver; Jürgen Diener; Stephan Fichtlscherer; Birgit Assmus; Florian H Seeger; Christian Menzel; Winfried Brenner; Stefanie Dimmeler; Andreas M Zeiher
Pilot trial on determinants of progenitor cell recruitment to the infarcted human myocardium.
Circulation 2008;118(14):1425-32.
2008: Michael Potente; Stefanie Dimmeler
NO targets SIRT1: a novel signaling network in endothelial senescence.
Arteriosclerosis, thrombosis, and vascular biology 2008;28(9):1577-9.
2008: Carmen Urbich; Elisabeth Dernbach; Lothar Rössig; Andreas M Zeiher; Stefanie Dimmeler
High glucose reduces cathepsin L activity and impairs invasion of circulating progenitor cells.
Journal of molecular and cellular cardiology 2008;45(3):429-36.
2008: Gianluigi Condorelli; Stefanie Dimmeler
MicroRNAs: components of an integrated system controlling cardiac development, physiology, and disease pathogenesis.
Cardiovascular research 2008;79(4):551-2.
2008: Carmen Urbich; Angelika Kuehbacher; Stefanie Dimmeler
Role of microRNAs in vascular diseases, inflammation, and angiogenesis.
Cardiovascular research 2008;79(4):581-8.
2008: Andrea Taddei; Costanza Giampietro; Annarita Conti; Fabrizio Orsenigo; Ferruccio Breviario; Valentina Pirazzoli; Michael Potente; Christopher Daly; Stefanie Dimmeler; Elisabetta Dejana
Endothelial adherens junctions control tight junctions by VE-cadherin-mediated upregulation of claudin-5.
Nature cell biology 2008;10(8):923-34.
2008: Stefan Rupp; Masamichi Koyanagi; Masayoshi Iwasaki; Jürgen Bauer; Susanne von Gerlach; Dietmar Schranz; Andreas M Zeiher; Stefanie Dimmeler
Characterization of long-term endogenous cardiac repair in children after heart transplantation.
European heart journal 2008;29(15):1867-72.
2008: Jana S Burchfield; Masayoshi Iwasaki; Masamichi Koyanagi; Carmen Urbich; Nadia Rosenthal; Andreas M Zeiher; Stefanie Dimmeler
Interleukin-10 from transplanted bone marrow mononuclear cells contributes to cardiac protection after myocardial infarction.
Circulation research 2008;103(2):203-11.
2008: Michael Potente; Stefanie Dimmeler
Emerging roles of SIRT1 in vascular endothelial homeostasis.
Cell cycle (Georgetown, Tex.) 2008;7(14):2117-22.
2008: Marc Tjwa; Stefanie Dimmeler
A nucleolar weapon in our fight for regenerating adult hearts: nucleostemin and cardiac stem cells.
Circulation research 2008;103(1):4-6.
2008: Stefan Rupp; Masamichi Koyanagi; Masayoshi Iwasaki; Florian Diehl; Philipp Bushoven; Dietmar Schranz; Andreas M Zeiher; Stefanie Dimmeler
Genetic proof-of-concept for cardiac gene expression in human circulating blood-derived progenitor cells.
Journal of the American College of Cardiology 2008;51(23):2289-90.
2008: Stefanie Dimmeler; Annarosa Leri
Aging and disease as modifiers of efficacy of cell therapy.
Circulation research 2008;102(11):1319-30.
2008: Katja Gueinzius; Astrid Magenau; Sonja Erath; Vanessa Wittke; Carmen Urbich; Elisa Ferrando-May; Stefanie Dimmeler; Corinna Hermann
Endothelial cells are protected against phagocyte-transmitted Chlamydophila pneumoniae infections by laminar shear stress Gueinzius: Shear stress protects from C. pneumoniae infection.
Atherosclerosis 2008;198(2):256-63.
2008: Warren Sherman; Stefanie Dimmeler; Joshua M Hare; Marc Penn
Cardiovascular repair and regeneration 2008: the fourth International Conference on Cell Therapy for Cardiovascular Disease (IC3D).
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 2008;4(1):47-9.
2008: Ioakim Spyridopoulos; Young Erben; Tim H Brummendorf; Judith Haendeler; Klaus Dietz; Florian H Seeger; Christine K Kissel; Hans Martin; Jedrzej Hoffmann; Birgit Assmus; Andreas M Zeiher; Stefanie Dimmeler
Telomere gap between granulocytes and lymphocytes is a determinant for hematopoetic progenitor cell impairment in patients with previous myocardial infarction.
Arteriosclerosis, thrombosis, and vascular biology 2008;28(5):968-74.
2008: Emmanouil Chavakis; Guillaume Carmona; Carmen Urbich; Stephan Göttig; Reinhard Henschler; Josef M Penninger; Andreas M Zeiher; Triantafyllos Chavakis; Stefanie Dimmeler
Phosphatidylinositol-3-kinase-gamma is integral to homing functions of progenitor cells.
Circulation research 2008;102(8):942-9.
2008: Maud Martin; Michael Potente; Veerle Janssens; Didier Vertommen; Jean-Claude Twizere; Mark H Rider; Jozef Goris; Stefanie Dimmeler; Richard Kettmann; Franck Dequiedt
Protein phosphatase 2A controls the activity of histone deacetylase 7 during T cell apoptosis and angiogenesis.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(12):4727-32.
2008: Guillaume Carmona; Emmanouil Chavakis; Ulrike Koehl; Andreas M Zeiher; Stefanie Dimmeler
Activation of Epac stimulates integrin-dependent homing of progenitor cells.
Blood 2008;111(5):2640-6.
2008: Stefanie Dimmeler; Jana Burchfield; Andreas M Zeiher
Cell-based therapy of myocardial infarction.
Arteriosclerosis, thrombosis, and vascular biology 2008;28(2):208-16.
2008: Jana S Burchfield; Stefanie Dimmeler
Role of paracrine factors in stem and progenitor cell mediated cardiac repair and tissue fibrosis.
Fibrogenesis & tissue repair 2008;1(1):4.
2008: Angelika Kuehbacher; Carmen Urbich; Stefanie Dimmeler
Targeting microRNA expression to regulate angiogenesis.
Trends in pharmacological sciences 2008;29(1):12-5.
2007: Jason C Kovacic; Richard P Harvey; Stefanie Dimmeler
Cardiovascular regenerative medicine: digging in for the long haul.
Cell stem cell 2007;1(6):628-33.
2007: Masamichi Koyanagi; Philipp Bushoven; Masayoshi Iwasaki; Carmen Urbich; Andreas M Zeiher; Stefanie Dimmeler
Notch signaling contributes to the expression of cardiac markers in human circulating progenitor cells.
Circulation research 2007;101(11):1139-45.
2007: Michael Potente; Laleh Ghaeni; danila baldessari; Raul Mostoslavsky; Lothar Rossig; Franck Dequiedt; Judith Haendeler; Marina Mione; Elisabetta Dejana; Frederick W Alt; Andreas M Zeiher; Stefanie Dimmeler
SIRT1 controls endothelial angiogenic functions during vascular growth.
Genes & development 2007;21(20):2644-58.
2007: Stefanie Dimmeler; Andreas M Zeiher
A "reductionist" view of cardiomyopathy.
Cell 2007;130(3):401-2.
2007: Sandra Erbs; Axel Linke; Volker Schächinger; Birgit Assmus; Holger Thiele; Klaus-Werner Diederich; Christina Hoffmann; Stefanie Dimmeler; Torsten Tonn; Rainer Hambrecht; Andreas M Zeiher; Gerhard Schuler
Restoration of microvascular function in the infarct-related artery by intracoronary transplantation of bone marrow progenitor cells in patients with acute myocardial infarction: the Doppler Substudy of the Reinfusion of Enriched Progenitor Cells and Infarct Remodeling in Acute Myocardial Infarction (REPAIR-AMI) trial.
Circulation 2007;116(4):366-74.
2007: Angelika Kuehbacher; Carmen Urbich; Andreas M Zeiher; Stefanie Dimmeler
Role of Dicer and Drosha for endothelial microRNA expression and angiogenesis.
Circulation research 2007;101(1):59-68.
2007: Christine K Kissel; Ralf Lehmann; Birgit Assmus; Alexandra Aicher; Jörg Honold; Ulrich Fischer-Rasokat; Christopher Heeschen; Ioakim Spyridopoulos; Stefanie Dimmeler; Andreas M Zeiher
Selective functional exhaustion of hematopoietic progenitor cells in the bone marrow of patients with postinfarction heart failure.
Journal of the American College of Cardiology 2007;49(24):2341-9.
2007: Caroline Schmidt-Lucke; Alexandra Aicher; Paola Romagnani; Björn Gareis; Sergio Romagnani; Andreas M Zeiher; Stefanie Dimmeler
Specific recruitment of CD4+CD25++ regulatory T cells into the allograft in heart transplant recipients.
American journal of physiology. Heart and circulatory physiology 2007;292(5):H2425-31.
2007: Birgit Assmus; Ulrich Fischer-Rasokat; Jörg Honold; Florian H Seeger; Stephan Fichtlscherer; Torsten Tonn; Erhard Seifried; Volker Schächinger; Stefanie Dimmeler; Andreas M Zeiher
Transcoronary transplantation of functionally competent BMCs is associated with a decrease in natriuretic peptide serum levels and improved survival of patients with chronic postinfarction heart failure: results of the TOPCARE-CHD Registry.
Circulation research 2007;100(8):1234-41.
2007: Christian Kupatt; Rabea Hinkel; Marie-Luise von Brühl; Tilmann Pohl; Jan Horstkotte; Philip Raake; Chiraz El Aouni; Eckart Thein; Stefanie Dimmeler; Olivier Feron; Peter Boekstegers
Endothelial nitric oxide synthase overexpression provides a functionally relevant angiogenic switch in hibernating pig myocardium.
Journal of the American College of Cardiology 2007;49(14):1575-84.
2007: Diana Aicher; Carmen Urbich; Andreas M Zeiher; Stefanie Dimmeler; Hans-Joachim Schäfers
Endothelial nitric oxide synthase in bicuspid aortic valve disease.
The Annals of thoracic surgery 2007;83(4):1290-4.
2007: Alexandra Aicher; Markus Rentsch; Ken-ichiro Sasaki; Joachim W Ellwart; Fred Fändrich; Reiner Siebert; john cooke; Stefanie Dimmeler; Christopher Heeschen
Nonbone marrow-derived circulating progenitor cells contribute to postnatal neovascularization following tissue ischemia.
Circulation research 2007;100(4):581-9.
2007: Florian H Seeger; Torsten Tonn; Nicola Krzossok; Andreas M Zeiher; Stefanie Dimmeler
Cell isolation procedures matter: a comparison of different isolation protocols of bone marrow mononuclear cells used for cell therapy in patients with acute myocardial infarction.
European heart journal 2007;28(6):766-72.
2007: Florian Diehl; Lothar Rössig; Andreas M Zeiher; Stefanie Dimmeler; Carmen Urbich
The histone methyltransferase MLL is an upstream regulator of endothelial-cell sprout formation.
Blood 2007;109(4):1472-8.
2007: Emmanouil Chavakis; Andreas Hain; Maria Vinci; Guillaume Carmona; Marco E Bianchi; Peter Vajkoczy; Andreas M Zeiher; Triantafyllos Chavakis; Stefanie Dimmeler
High-mobility group box 1 activates integrin-dependent homing of endothelial progenitor cells.
Circulation research 2007;100(2):204-12.
2007: Florian H Seeger; Andreas M Zeiher; Stefanie Dimmeler
Cell-enhancement strategies for the treatment of ischemic heart disease.
Nature clinical practice. Cardiovascular medicine 2007;4 Suppl 1():S110-3.
2007: Dirk H Walter; Ulrich Rochwalsky; Johannes Reinhold; Florian H Seeger; Alexandra Aicher; Carmen Urbich; Ioakim Spyridopoulos; Jerold Chun; Volker Brinkmann; Petra Keul; Bodo Levkau; Andreas M Zeiher; Stefanie Dimmeler; Judith Haendeler
Sphingosine-1-phosphate stimulates the functional capacity of progenitor cells by activation of the CXCR4-dependent signaling pathway via the S1P3 receptor.
Arteriosclerosis, thrombosis, and vascular biology 2007;27(2):275-82.
2007: Ioakim Spyridopoulos; Stefanie Dimmeler
Can telomere length predict cardiovascular risk?
Lancet 2007;369(9556):81-2.
2006: Alexandra Aicher; Christopher Heeschen; Ken-ichiro Sasaki; Carmen Urbich; Andreas M Zeiher; Stefanie Dimmeler
Low-energy shock wave for enhancing recruitment of endothelial progenitor cells: a new modality to increase efficacy of cell therapy in chronic hind limb ischemia.
Circulation 2006;114(25):2823-30.
2006: Volker Schächinger; Sandra Erbs; Albrecht Elsässer; Werner Haberbosch; Rainer Hambrecht; Hans Hölschermann; Jiangtao Yu; Roberto Corti; Detlef G Mathey; Christian W Hamm; Tim Süselbeck; Nikos Werner; Jürgen Haase; Joerg Neuzner; Alfried Germing; Bernd Mark; Birgit Assmus; Torsten Tonn; Stefanie Dimmeler; Andreas M Zeiher
Improved clinical outcome after intracoronary administration of bone-marrow-derived progenitor cells in acute myocardial infarction: final 1-year results of the REPAIR-AMI trial.
European heart journal 2006;27(23):2775-83.
2006: Birgit Assmus; Dirk H Walter; Ralf Lehmann; Jörg Honold; Hans Martin; Stefanie Dimmeler; Andreas M Zeiher; Volker Schächinger
Intracoronary infusion of progenitor cells is not associated with aggravated restenosis development or atherosclerotic disease progression in patients with acute myocardial infarction.
European heart journal 2006;27(24):2989-95.
2006: Jörg Honold; Ralf Lehmann; Christopher Heeschen; Dirk H Walter; Birgit Assmus; Ken-ichiro Sasaki; Hans Martin; Judith Haendeler; Andreas M Zeiher; Stefanie Dimmeler
Effects of granulocyte colony simulating factor on functional activities of endothelial progenitor cells in patients with chronic ischemic heart disease.
Arteriosclerosis, thrombosis, and vascular biology 2006;26(10):2238-43.
2006: Ken-ichiro Sasaki; Christopher Heeschen; Alexandra Aicher; Thomas Ziebart; Jörg Honold; Carmen Urbich; Lothar Rossig; Ulrike Koehl; Masamichi Koyanagi; Annisuddin Mohamed; Ralf P Brandes; Hans Martin; Andreas M Zeiher; Stefanie Dimmeler
Ex vivo pretreatment of bone marrow mononuclear cells with endothelial NO synthase enhancer AVE9488 enhances their functional activity for cell therapy.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(39):14537-41.
2006: Birgit Assmus; Jörg Honold; Volker Schächinger; Martina B Britten; Ulrich Fischer-Rasokat; Ralf Lehmann; Claudius Teupe; Katrin Pistorius; Hans Martin; Nasreddin D Abolmaali; Torsten Tonn; Stefanie Dimmeler; Andreas M Zeiher
Transcoronary transplantation of progenitor cells after myocardial infarction.
The New England journal of medicine 2006;355(12):1222-32.
2006: Volker Schächinger; Sandra Erbs; Albrecht Elsässer; Werner Haberbosch; Rainer Hambrecht; Hans Hölschermann; Jiangtao Yu; Roberto Corti; Detlef G Mathey; Christian W Hamm; Tim Süselbeck; Birgit Assmus; Torsten Tonn; Stefanie Dimmeler; Andreas M Zeiher
Intracoronary bone marrow-derived progenitor cells in acute myocardial infarction.
The New England journal of medicine 2006;355(12):1210-21.
2006: Stefanie Dimmeler
Viewpoint: stem cells in cardiology.
Circulation 2006;113(18):f69-70.
2006: Stephan Fichtlscherer; Caroline Schmidt-Lucke; Susanne Bojunga; Lothar Rössig; Christopher Heeschen; Stefanie Dimmeler; Andreas M Zeiher
Differential effects of short-term lipid lowering with ezetimibe and statins on endothelial function in patients with CAD: clinical evidence for 'pleiotropic' functions of statin therapy.
European heart journal 2006;27(10):1182-90.
2006: Volker Schächinger; Stefanie Dimmeler; Andreas M Zeiher
[Stem cells after myocardial infarction].
Herz 2006;31(2):127-36; quiz 142-3.
2006: Volker Schächinger; Torsten Tonn; Stefanie Dimmeler; Andreas M Zeiher
Bone-marrow-derived progenitor cell therapy in need of proof of concept: design of the REPAIR-AMI trial.
Nature clinical practice. Cardiovascular medicine 2006;3 Suppl 1():S23-8.
2006: Judith Haendeler; Stefanie Dimmeler
Inseparably tied: functional and antioxidative capacity of endothelial progenitor cells.
Circulation research 2006;98(2):157-8.
2006: Timo Lenderink; Christopher Heeschen; Stephan Fichtlscherer; Stefanie Dimmeler; Christian W Hamm; Andreas M Zeiher; Maarten L Simoons; eric boersma
Elevated placental growth factor levels are associated with adverse outcomes at four-year follow-up in patients with acute coronary syndromes.
Journal of the American College of Cardiology 2006;47(2):307-11.
2006: Carmen Urbich; Lothar Rössig; Stefanie Dimmeler
Restoration of cardiac function with progenitor cells.
Novartis Foundation symposium 2006;274():214-23; discussion 223-7, 272-6.
2006: Volker Schächinger; Birgit Assmus; Jörg Honold; Ralf Lehmann; Wolf-Karsten Hofmann; Hans Martin; Stefanie Dimmeler; Andreas M Zeiher
Normalization of coronary blood flow in the infarct-related artery after intracoronary progenitor cell therapy: intracoronary Doppler substudy of the TOPCARE-AMI trial.
Clinical research in cardiology : official journal of the German Cardiac Society 2006;95(1):13-22.
2006: Cornel Badorff; Stefanie Dimmeler
Neovascularization and cardiac repair by bone marrow-derived stem cells.
Handbook of experimental pharmacology 2006;(174):283-98.
2005: Judith Haendeler; Rüdiger Popp; Christine Goy; Verena Tischler; Andreas M Zeiher; Stefanie Dimmeler
Cathepsin D and H2O2 stimulate degradation of thioredoxin-1: implication for endothelial cell apoptosis.
The Journal of biological chemistry 2005;280(52):42945-51.
2005: Frank M Bengel; Volker Schachinger; Stefanie Dimmeler
Cell-based therapies and imaging in cardiology.
European journal of nuclear medicine and molecular imaging 2005;32 Suppl 2():S404-16.
2005: Dirk H Walter; Judith Haendeler; Johannes Reinhold; Ulrich Rochwalsky; Florian H Seeger; Jörg Honold; Jörg Hoffmann; Carmen Urbich; Ralf Lehmann; Fernando Arenzana-Seisdesdos; Alexandra Aicher; Christopher Heeschen; Stephan Fichtlscherer; Andreas M Zeiher; Stefanie Dimmeler
Impaired CXCR4 signaling contributes to the reduced neovascularization capacity of endothelial progenitor cells from patients with coronary artery disease.
Circulation research 2005;97(11):1142-51.
2005: Masamichi Koyanagi; Carmen Urbich; Emmanouil Chavakis; Jörg Hoffmann; Stefan Rupp; Cornel Badorff; Andreas M Zeiher; Anna Starzinski-Powitz; Judith Haendeler; Stefanie Dimmeler
Differentiation of circulating endothelial progenitor cells to a cardiomyogenic phenotype depends on E-cadherin.
FEBS letters 2005;579(27):6060-6.
2005: Stefanie Dimmeler
ATVB in focus: novel mediators and mechanisms in angiogenesis and vasculogenesis.
Arteriosclerosis, thrombosis, and vascular biology 2005;25(11):2245.
2005: Carmen Urbich; Alexandra Aicher; Christopher Heeschen; Elisabeth Dernbach; Wolf-Karsten Hofmann; Andreas M Zeiher; Stefanie Dimmeler
Soluble factors released by endothelial progenitor cells promote migration of endothelial cells and cardiac resident progenitor cells.
Journal of molecular and cellular cardiology 2005;39(5):733-42.
2005: Cornel Badorff; Florian H Seeger; Andreas M Zeiher; Stefanie Dimmeler
Glycogen synthase kinase 3beta inhibits myocardin-dependent transcription and hypertrophy induction through site-specific phosphorylation.
Circulation research 2005;97(7):645-54.
2005: Michael Potente; Carmen Urbich; Ken-ichiro Sasaki; Wolf-Karsten Hofmann; Christopher Heeschen; Alexandra Aicher; Ramya Kollipara; Ronald A DePinho; Andreas M Zeiher; Stefanie Dimmeler
Involvement of Foxo transcription factors in angiogenesis and postnatal neovascularization.
The Journal of clinical investigation 2005;115(9):2382-92.
2005: Paola Romagnani; Francesco Annunziato; Francesco Liotta; Elena Lazzeri; Benedetta Mazzinghi; Francesca Frosali; Lorenzo Cosmi; Laura Maggi; Laura Lasagni; Alexander Scheffold; Manuela Kruger; Stefanie Dimmeler; Fabio Marra; Gianfranco Gensini; Enrico Maggi; Sergio Romagnani
CD14+CD34low cells with stem cell phenotypic and functional features are the major source of circulating endothelial progenitors.
Circulation research 2005;97(4):314-22.
2005: Caroline Schmidt-Lucke; Lothar Rössig; Stephan Fichtlscherer; Mariuca Vasa; Martina B Britten; Ulrike Kämper; Stefanie Dimmeler; Andreas M Zeiher
Reduced number of circulating endothelial progenitor cells predicts future cardiovascular events: proof of concept for the clinical importance of endogenous vascular repair.
Circulation 2005;111(22):2981-7.
2005: Lothar Rössig; Carmen Urbich; Thomas Brühl; Elisabeth Dernbach; Christopher Heeschen; Emmanouil Chavakis; Ken-ichiro Sasaki; Diana Aicher; Florian Diehl; Florian H Seeger; Michael Potente; Alexandra Aicher; Lucia Zanetta; Elisabetta Dejana; Andreas M Zeiher; Stefanie Dimmeler
Histone deacetylase activity is essential for the expression of HoxA9 and for endothelial commitment of progenitor cells.
The Journal of experimental medicine 2005;201(11):1825-35.
2005: Hartmut Ruetten; Stefanie Dimmeler; Doris Gehring; Christian Ihling; Andreas M Zeiher
Concentric left ventricular remodeling in endothelial nitric oxide synthase knockout mice by chronic pressure overload.
Cardiovascular research 2005;66(3):444-53.
2005: Carmen Urbich; Andrea Knau; Stephan Fichtlscherer; Dirk H Walter; Thomas Brühl; Michael Potente; Wolf-Karsten Hofmann; Sven de Vos; Andreas M Zeiher; Stefanie Dimmeler
FOXO-dependent expression of the proapoptotic protein Bim: pivotal role for apoptosis signaling in endothelial progenitor cells.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(8):974-6.
2005: Masamichi Koyanagi; Ralf P Brandes; Judith Haendeler; Andreas M Zeiher; Stefanie Dimmeler
Cell-to-cell connection of endothelial progenitor cells with cardiac myocytes by nanotubes: a novel mechanism for cell fate changes?
Circulation research 2005;96(10):1039-41.
2005: Carmen Urbich; Stefanie Dimmeler
Risk factors for coronary artery disease, circulating endothelial progenitor cells, and the role of HMG-CoA reductase inhibitors.
Kidney international 2005;67(5):1672-6.
2005: Masamichi Koyanagi; Judith Haendeler; Cornel Badorff; Ralf P Brandes; Jörg Hoffmann; Petra Pandur; Andreas M Zeiher; Michael Kühl; Stefanie Dimmeler
Non-canonical Wnt signaling enhances differentiation of human circulating progenitor cells to cardiomyogenic cells.
The Journal of biological chemistry 2005;280(17):16838-42.
2005: Stefanie Dimmeler
Platelet-derived growth factor CC--a clinically useful angiogenic factor at last?
The New England journal of medicine 2005;352(17):1815-6.
2005: Florian H Seeger; Judith Haendeler; Dirk H Walter; Ulrich Rochwalsky; Johannes Reinhold; Carmen Urbich; Lothar Rössig; Anne Corbaz; Yolande Chvatchko; Andreas M Zeiher; Stefanie Dimmeler
p38 mitogen-activated protein kinase downregulates endothelial progenitor cells.
Circulation 2005;111(9):1184-91.
2005: Stefanie Dimmeler; Andreas M Zeiher; Michael D Schneider
Unchain my heart: the scientific foundations of cardiac repair.
The Journal of clinical investigation 2005;115(3):572-83.
2005: Alexandra Aicher; Andreas M Zeiher; Stefanie Dimmeler
Mobilizing endothelial progenitor cells.
Hypertension 2005;45(3):321-5.
2005: Carmen Urbich; Christopher Heeschen; Alexandra Aicher; Ken-ichiro Sasaki; Thomas Bruhl; Mohammad R Farhadi; Peter Vajkoczy; Wolf-Karsten Hofmann; Christoph Peters; Len A Pennacchio; Nasreddin D Abolmaali; Emmanouil Chavakis; Thomas Reinheckel; Andreas M Zeiher; Stefanie Dimmeler
Cathepsin L is required for endothelial progenitor cell-induced neovascularization.
Nature medicine 2005;11(2):206-13.
2005: Christopher Heeschen; Stefanie Dimmeler; Christian W Hamm; Stephan Fichtlscherer; Maarten L Simoons; Andreas M Zeiher
Pregnancy-associated plasma protein-A levels in patients with acute coronary syndromes: comparison with markers of systemic inflammation, platelet activation, and myocardial necrosis.
Journal of the American College of Cardiology 2005;45(2):229-37.
2005: Emmanouil Chavakis; Alexandra Aicher; Christopher Heeschen; Ken-ichiro Sasaki; Ralf Kaiser; Naual El Makhfi; Carmen Urbich; Thorsten Peters; Karin Scharffetter-Kochanek; Andreas M Zeiher; Triantafyllos Chavakis; Stefanie Dimmeler
Role of beta2-integrins for homing and neovascularization capacity of endothelial progenitor cells.
The Journal of experimental medicine 2005;201(1):63-72.
2004: Elisabeth Dernbach; Carmen Urbich; Ralf P Brandes; Wolf-Karsten Hofmann; Andreas M Zeiher; Stefanie Dimmeler
Antioxidative stress-associated genes in circulating progenitor cells: evidence for enhanced resistance against oxidative stress.
Blood 2004;104(12):3591-7.
2004: Judith Haendeler; Verena Tischler; Jörg Hoffmann; Andreas M Zeiher; Stefanie Dimmeler
Low doses of reactive oxygen species protect endothelial cells from apoptosis by increasing thioredoxin-1 expression.
FEBS letters 2004;577(3):427-33.
2004: Ioakim Spyridopoulos; Judith Haendeler; Carmen Urbich; Tim H Brummendorf; Hidemasa Oh; Michael D Schneider; Andreas M Zeiher; Stefanie Dimmeler
Statins enhance migratory capacity by upregulation of the telomere repeat-binding factor TRF2 in endothelial progenitor cells.
Circulation 2004;110(19):3136-42.
2004: Dirk H Walter; Stefanie Dimmeler; Andreas M Zeiher
Effects of statins on endothelium and endothelial progenitor cell recruitment.
Seminars in vascular medicine 2004;4(4):385-93.
2004: Carmen Urbich; Stefanie Dimmeler
Endothelial progenitor cells functional characterization.
Trends in cardiovascular medicine 2004;14(8):318-22.
2004: Lothar Rössig; Carmen Urbich; Stefanie Dimmeler
Endothelial progenitor cells at work: not mature yet, but already stress-resistant.
Arteriosclerosis, thrombosis, and vascular biology 2004;24(11):1977-9.
2004: Volker Schächinger; Birgit Assmus; Martina B Britten; Jörg Honold; Ralf Lehmann; Claudius Teupe; Nasreddin D Abolmaali; Thomas J Vogl; Wolf-Karsten Hofmann; Hans Martin; Stefanie Dimmeler; Andreas M Zeiher
Transplantation of progenitor cells and regeneration enhancement in acute myocardial infarction: final one-year results of the TOPCARE-AMI Trial.
Journal of the American College of Cardiology 2004;44(8):1690-9.
2004: Stefanie Dimmeler; Andreas M Zeiher
Vascular repair by circulating endothelial progenitor cells: the missing link in atherosclerosis?
Journal of molecular medicine (Berlin, Germany) 2004;82(10):671-7.
2004: Lothar Rössig; Stephan Fichtlscherer; Christopher Heeschen; Jürgen Berger; Stefanie Dimmeler; Andreas M Zeiher
The pro-apoptotic serum activity is an independent mortality predictor of patients with heart failure.
European heart journal 2004;25(18):1620-5.
2004: Alexandra Aicher; Christopher Heeschen; Stefanie Dimmeler
The role of NOS3 in stem cell mobilization.
Trends in molecular medicine 2004;10(9):421-5.
2004: Carmen Urbich; Stefanie Dimmeler
Endothelial progenitor cells: characterization and role in vascular biology.
Circulation research 2004;95(4):343-53.
2004: Judith Haendeler; Jörg Hoffmann; Andreas M Zeiher; Stefanie Dimmeler
Antioxidant effects of statins via S-nitrosylation and activation of thioredoxin in endothelial cells: a novel vasculoprotective function of statins.
Circulation 2004;110(7):856-61.
2004: Stephan Fichtlscherer; Susanne Breuer; Volker Schächinger; Stefanie Dimmeler; Andreas M Zeiher
C-reactive protein levels determine systemic nitric oxide bioavailability in patients with coronary artery disease.
European heart journal 2004;25(16):1412-8.
2004: Dirk H Walter; Andreas M Zeiher; Stefanie Dimmeler
Effects of statins on endothelium and their contribution to neovascularization by mobilization of endothelial progenitor cells.
Coronary artery disease 2004;15(5):235-42.
2004: Natascha Döbert; Martina B Britten; Birgit Assmus; Uwe Berner; Christian Menzel; Ralf Lehmann; Nadja Hamscho; Volker Schächinger; Stefanie Dimmeler; Andreas M Zeiher; Frank Grünwald
Transplantation of progenitor cells after reperfused acute myocardial infarction: evaluation of perfusion and myocardial viability with FDG-PET and thallium SPECT.
European journal of nuclear medicine and molecular imaging 2004;31(8):1146-51.
2004: Stefanie Dimmeler; Andreas M Zeiher
Wanted! The best cell for cardiac regeneration.
Journal of the American College of Cardiology 2004;44(2):464-6.
2004: Stephan Fichtlscherer; Susanne Breuer; Christopher Heeschen; Stefanie Dimmeler; Andreas M Zeiher
Interleukin-10 serum levels and systemic endothelial vasoreactivity in patients with coronary artery disease.
Journal of the American College of Cardiology 2004;44(1):44-9.
2004: Jörg Honold; Birgit Assmus; Ralf Lehman; Andreas M Zeiher; Stefanie Dimmeler
Stem cell therapy of cardiac disease: an update.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2004;19(7):1673-7.
2004: Douglas Losordo; Stefanie Dimmeler
Therapeutic angiogenesis and vasculogenesis for ischemic disease: part II: cell-based therapies.
Circulation 2004;109(22):2692-7.
2004: Douglas Losordo; Stefanie Dimmeler
Therapeutic angiogenesis and vasculogenesis for ischemic disease. Part I: angiogenic cytokines.
Circulation 2004;109(21):2487-91.
2004: Carmen Urbich; Stefanie Dimmeler
CD40 and vascular inflammation.
The Canadian journal of cardiology 2004;20(7):681-3.
2004: Stephan Fichtlscherer; Marietta Kaszkin; Susanne Breuer; Stefanie Dimmeler; Andreas M Zeiher
Elevated secretory non-pancreatic type II phospholipase A2 serum activity is associated with impaired endothelial vasodilator function in patients with coronary artery disease.
Clinical science (London, England : 1979) 2004;106(5):511-7.
2004: Christopher Heeschen; Ralf Lehmann; Jörg Honold; Birgit Assmus; Alexandra Aicher; Dirk H Walter; Hans Martin; Andreas M Zeiher; Stefanie Dimmeler
Profoundly reduced neovascularization capacity of bone marrow mononuclear cells derived from patients with chronic ischemic heart disease.
Circulation 2004;109(13):1615-22.
2004: Judith Haendeler; Jörg Hoffmann; J Florian Diehl; Mariuca Vasa; Ioakim Spyridopoulos; Andreas M Zeiher; Stefanie Dimmeler
Antioxidants inhibit nuclear export of telomerase reverse transcriptase and delay replicative senescence of endothelial cells.
Circulation research 2004;94(6):768-75.
2004: Thomas Bruhl; Carmen Urbich; Diana Aicher; Amparo Acker-Palmer; Andreas M Zeiher; Stefanie Dimmeler
Homeobox A9 transcriptionally regulates the EphB4 receptor to modulate endothelial cell migration and tube formation.
Circulation research 2004;94(6):743-51.
2004: Thomas Brühl; Christopher Heeschen; Alexandra Aicher; Amir S Jadidi; Judith Haendeler; Jörg Hoffmann; Michael D Schneider; Andreas M Zeiher; Stefanie Dimmeler; Lothar Rössig
p21Cip1 levels differentially regulate turnover of mature endothelial cells, endothelial progenitor cells, and in vivo neovascularization.
Circulation research 2004;94(5):686-92.
2004: Winfried Brenner; Alexandra Aicher; Thomas Eckey; Schirin Massoudi; Maaz Zuhayra; Ulrike Koehl; Christopher Heeschen; Willm Uwe Kampen; Andreas M Zeiher; Stefanie Dimmeler; Eberhard Henze
111In-labeled CD34+ hematopoietic progenitor cells in a rat myocardial infarction model.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2004;45(3):512-8.
2004: Christopher Heeschen; Stefanie Dimmeler; Stephan Fichtlscherer; Christian W Hamm; Juergen Berger; Maarten L Simoons; Andreas M Zeiher
Prognostic value of placental growth factor in patients with acute chest pain.
JAMA : the journal of the American Medical Association 2004;291(4):435-41.
2004: Stephan Fichtlscherer; Stefanie Dimmeler; Susanne Breuer; Rudi Busse; Andreas M Zeiher; Ingrid Fleming
Inhibition of cytochrome P450 2C9 improves endothelium-dependent, nitric oxide-mediated vasodilatation in patients with coronary artery disease.
Circulation 2004;109(2):178-83.
2004: Stefan Rupp; Cornel Badorff; Masamichi Koyanagi; Carmen Urbich; Stephan Fichtlscherer; Alexandra Aicher; Andreas M Zeiher; Stefanie Dimmeler
Statin therapy in patients with coronary artery disease improves the impaired endothelial progenitor cell differentiation into cardiomyogenic cells.
Basic research in cardiology 2004;99(1):61-8.
2004: Dirk Henrich; Patrick Hahn; Matthias Wahl; Kerstin Wilhelm; Elisabeth Dernbach; Stefanie Dimmeler; Ingo Marzi
Serum derived from multiple trauma patients promotes the differentiation of endothelial progenitor cells in vitro: possible role of transforming growth factor-beta1 and vascular endothelial growth factor165.
Shock (Augusta, Ga.) 2004;21(1):13-6.
2003: Stefanie Dimmeler; Mariuca Vasa-Nicotera
Aging of progenitor cells: limitation for regenerative capacity?
Journal of the American College of Cardiology 2003;42(12):2081-2.
2003: Carmen Urbich; Christopher Heeschen; Alexandra Aicher; Elisabeth Dernbach; Andreas M Zeiher; Stefanie Dimmeler
Relevance of monocytic features for neovascularization capacity of circulating endothelial progenitor cells.
Circulation 2003;108(20):2511-6.
2003: Martina B Britten; Nasreddin D Abolmaali; Birgit Assmus; Ralf Lehmann; Jörg Honold; J Schmitt; Thomas J Vogl; Hans Martin; Volker Schächinger; Stefanie Dimmeler; Andreas M Zeiher
Infarct remodeling after intracoronary progenitor cell treatment in patients with acute myocardial infarction (TOPCARE-AMI): mechanistic insights from serial contrast-enhanced magnetic resonance imaging.
Circulation 2003;108(18):2212-8.
2003: Alexandra Aicher; Christopher Heeschen; Christiane Mildner-Rihm; Carmen Urbich; Christian Ihling; Katja Technau-Ihling; Andreas M Zeiher; Stefanie Dimmeler
Essential role of endothelial nitric oxide synthase for mobilization of stem and progenitor cells.
Nature medicine 2003;9(11):1370-6.
2003: Sonja Von Aulock; Nicolas W J Schröder; Katja Gueinzius; Stephanie Traub; Sebastian Hoffmann; Kathrin Graf; Stefanie Dimmeler; Thomas Hartung; Ralf R Schumann; Corinna Hermann
Heterozygous toll-like receptor 4 polymorphism does not influence lipopolysaccharide-induced cytokine release in human whole blood.
The Journal of infectious diseases 2003;188(6):938-43.
2003: Jörg Hoffmann; Stefanie Dimmeler; Judith Haendeler
Shear stress increases the amount of S-nitrosylated molecules in endothelial cells: important role for signal transduction.
FEBS letters 2003;551(1-3):153-8.
2003: Christopher Heeschen; Alexandra Aicher; Ralf Lehmann; Stephan Fichtlscherer; Mariuca Vasa; Carmen Urbich; Christiane Mildner-Rihm; Hans Martin; Andreas M Zeiher; Stefanie Dimmeler
Erythropoietin is a potent physiologic stimulus for endothelial progenitor cell mobilization.
Blood 2003;102(4):1340-6.
2003: Stefanie Dimmeler; Andreas M Zeiher
Exercise and cardiovascular health: get active to "AKTivate" your endothelial nitric oxide synthase.
Circulation 2003;107(25):3118-20.
2003: Judith Haendeler; Jörg Hoffmann; Ralf P Brandes; Andreas M Zeiher; Stefanie Dimmeler
Hydrogen peroxide triggers nuclear export of telomerase reverse transcriptase via Src kinase family-dependent phosphorylation of tyrosine 707.
Molecular and cellular biology 2003;23(13):4598-610.
2003: Birgit Assmus; Carmen Urbich; Alexandra Aicher; Wolf-Karsten Hofmann; Judith Haendeler; Lothar Rössig; Ioakim Spyridopoulos; Andreas M Zeiher; Stefanie Dimmeler
HMG-CoA reductase inhibitors reduce senescence and increase proliferation of endothelial progenitor cells via regulation of cell cycle regulatory genes.
Circulation research 2003;92(9):1049-55.
2003: Alexandra Aicher; Winfried Brenner; Maaz Zuhayra; Cornel Badorff; Schirin Massoudi; Birgit Assmus; Thomas Eckey; Eberhard Henze; Andreas M Zeiher; Stefanie Dimmeler
Assessment of the tissue distribution of transplanted human endothelial progenitor cells by radioactive labeling.
Circulation 2003;107(16):2134-9.
2003: Christopher Heeschen; Stefanie Dimmeler; Christian W Hamm; Stephan Fichtlscherer; eric boersma; Maarten L Simoons; Andreas M Zeiher
Serum level of the antiinflammatory cytokine interleukin-10 is an important prognostic determinant in patients with acute coronary syndromes.
Circulation 2003;107(16):2109-14.
2003: Christian Kupatt; Rabea Hinkel; Robert Vachenauer; Jan Horstkotte; Philip Raake; Torleif Sandner; Robert Kreuzpointner; Fabian Müller; Stefanie Dimmeler; Olivier Feron; Peter Boekstegers
VEGF165 transfection decreases postischemic NF-kappa B-dependent myocardial reperfusion injury in vivo: role of eNOS phosphorylation.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003;17(6):705-7.
2003: Christopher Heeschen; Stefanie Dimmeler; Christian W Hamm; M J B M van den Brand; eric boersma; Andreas M Zeiher; Maarten L Simoons
Soluble CD40 ligand in acute coronary syndromes.
The New England journal of medicine 2003;348(12):1104-11.
2003: Cornel Badorff; Stefanie Dimmeler
NO balance: regulation of the cytoskeleton in congestive heart failure by nitric oxide.
Circulation 2003;107(10):1348-9.
2003: Cornel Badorff; Ralf P Brandes; Rüdiger Popp; Stefan Rupp; Carmen Urbich; Alexandra Aicher; Ingrid Fleming; Rudi Busse; Andreas M Zeiher; Stefanie Dimmeler
Transdifferentiation of blood-derived human adult endothelial progenitor cells into functionally active cardiomyocytes.
Circulation 2003;107(7):1024-32.
2003: Judith Haendeler; Jörg Hoffmann; Sandy Rahman; Andreas M Zeiher; Stefanie Dimmeler
Regulation of telomerase activity and anti-apoptotic function by protein-protein interaction and phosphorylation.
FEBS letters 2003;536(1-3):180-6.
2003: Alexandra Aicher; Christopher Heeschen; Mariette Mohaupt; john cooke; Andreas M Zeiher; Stefanie Dimmeler
Nicotine strongly activates dendritic cell-mediated adaptive immunity: potential role for progression of atherosclerotic lesions.
Circulation 2003;107(4):604-11.
2003: Christopher Heeschen; Stefanie Dimmeler; Christian W Hamm; eric boersma; Andreas M Zeiher; Maarten L Simoons
Prognostic significance of angiogenic growth factor serum levels in patients with acute coronary syndromes.
Circulation 2003;107(4):524-30.
2003: Carmen Urbich; Monika Stein; Kerstin Reisinger; Roland Kaufmann; Stefanie Dimmeler; Jens Gille
Fluid shear stress-induced transcriptional activation of the vascular endothelial growth factor receptor-2 gene requires Sp1-dependent DNA binding.
FEBS letters 2003;535(1-3):87-93.
2002: Birgit Assmus; Volker Schächinger; Claudius Teupe; Martina B Britten; Ralf Lehmann; Natascha Döbert; Frank Grünwald; Alexandra Aicher; Carmen Urbich; Hans Martin; Dieter Hoelzer; Stefanie Dimmeler; Andreas M Zeiher
Transplantation of Progenitor Cells and Regeneration Enhancement in Acute Myocardial Infarction (TOPCARE-AMI).
Circulation 2002;106(24):3009-17.
2002: Dirk H Walter; Stefanie Dimmeler
Endothelial progenitor cells: regulation and contribution to adult neovascularization.
Herz 2002;27(7):579-88.
2002: Lothar Rössig; Huige Li; Beate Fisslthaler; Carmen Urbich; Ingrid Fleming; Ulrich Förstermann; Andreas M Zeiher; Stefanie Dimmeler
Inhibitors of histone deacetylation downregulate the expression of endothelial nitric oxide synthase and compromise endothelial cell function in vasorelaxation and angiogenesis.
Circulation research 2002;91(9):837-44.
2002: Stefanie Dimmeler; Judith Haendeler; Andreas M Zeiher
Regulation of endothelial cell apoptosis in atherothrombosis.
Current opinion in lipidology 2002;13(5):531-6.
2002: Judith Haendeler; Jörg Hoffmann; Verena Tischler; Bradford C Berk; Andreas M Zeiher; Stefanie Dimmeler
Redox regulatory and anti-apoptotic functions of thioredoxin depend on S-nitrosylation at cysteine 69.
Nature cell biology 2002;4(10):743-9.
2002: Carmen Urbich; Elisabeth Dernbach; Alexandra Aicher; Andreas M Zeiher; Stefanie Dimmeler
CD40 ligand inhibits endothelial cell migration by increasing production of endothelial reactive oxygen species.
Circulation 2002;106(8):981-6.
2002: Christopher Heeschen; Michael Weis; Alexandra Aicher; Stefanie Dimmeler; john cooke
A novel angiogenic pathway mediated by non-neuronal nicotinic acetylcholine receptors.
The Journal of clinical investigation 2002;110(4):527-36.
2002: Frank Jung; Judith Haendeler; Jörg Hoffmann; Agnes Reissner; Elisabeth Dernbach; Andreas M Zeiher; Stefanie Dimmeler
Hypoxic induction of the hypoxia-inducible factor is mediated via the adaptor protein Shc in endothelial cells.
Circulation research 2002;91(1):38-45.
2002: Emmanouil Chavakis; Stefanie Dimmeler
Regulation of endothelial cell survival and apoptosis during angiogenesis.
Arteriosclerosis, thrombosis, and vascular biology 2002;22(6):887-93.
2002: Cornel Badorff; Birgit Fichtlscherer; Alexander Muelsch; Andreas M Zeiher; Stefanie Dimmeler
Selective delivery of nitric oxide to a cellular target: a pseudosubstrate-coupled dinitrosyl-iron complex inhibits the enteroviral protease 2A.
Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society 2002;6(3):305-12.
2002: Stefanie Dimmeler; Andreas M Zeiher
PTEN-uating restenosis.
Arteriosclerosis, thrombosis, and vascular biology 2002;22(5):715-6.
2002: Carmen Urbich; Agnes Reissner; Emmanouil Chavakis; Elisabeth Dernbach; Judith Haendeler; Iingrid Fleming; Andreas M Zeiher; Marietta Kaszkin; Stefanie Dimmeler
Dephosphorylation of endothelial nitric oxide synthase contributes to the anti-angiogenic effects of endostatin.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002;16(7):706-8.
2002: Carmen Urbich; Elisabeth Dernbach; Andreas M Zeiher; Stefanie Dimmeler
Double-edged role of statins in angiogenesis signaling.
Circulation research 2002;90(6):737-44.
2002: Anke Burger-Kentischer; Heike Goebel; Rüdiger Seiler; Gustav Fraedrich; Hans-Eckart Schaefer; Stefanie Dimmeler; Robert Kleemann; Jürgen Bernhagen; Christian Ihling
Expression of macrophage migration inhibitory factor in different stages of human atherosclerosis.
Circulation 2002;105(13):1561-6.
2002: Lothar Rössig; Cornel Badorff; Yvonne Holzmann; Andreas M Zeiher; Stefanie Dimmeler
Glycogen synthase kinase-3 couples AKT-dependent signaling to the regulation of p21Cip1 degradation.
The Journal of biological chemistry 2002;277(12):9684-9.
2002: Claudius Teupe; Sergio Richter; Beate Fisslthaler; Voahanginirina Randriamboavonjy; Christian Ihling; Ingrid Fleming; Rudi Busse; Andreas M Zeiher; Stefanie Dimmeler
Vascular gene transfer of phosphomimetic endothelial nitric oxide synthase (S1177D) using ultrasound-enhanced destruction of plasmid-loaded microbubbles improves vasoreactivity.
Circulation 2002;105(9):1104-9.
2002: Cornel Badorff; Hartmut Ruetten; Sven Mueller; Meike Stahmer; Doris Gehring; Frank Jung; Christian Ihling; Andreas M Zeiher; Stefanie Dimmeler
Fas receptor signaling inhibits glycogen synthase kinase 3 beta and induces cardiac hypertrophy following pressure overload.
The Journal of clinical investigation 2002;109(3):373-81.
2002: Lothar Rössig; Corinna Hermann; Judith Haendeler; Birgit Assmus; Andreas M Zeiher; Stefanie Dimmeler
Angiotensin II-induced upregulation of MAP kinase phosphatase-3 mRNA levels mediates endothelial cell apoptosis.
Basic research in cardiology 2002;97(1):1-8.
2002: Carmen Urbich; Elisabeth Dernbach; Agnes Reissner; Mariuca Vasa; Andreas M Zeiher; Stefanie Dimmeler
Shear stress-induced endothelial cell migration involves integrin signaling via the fibronectin receptor subunits alpha(5) and beta(1).
Arteriosclerosis, thrombosis, and vascular biology 2002;22(1):69-75.
2001: Stephan Fichtlscherer; Lothar Rössig; Susanne Breuer; Mariuca Vasa; Stefanie Dimmeler; Andreas M Zeiher
Tumor necrosis factor antagonism with etanercept improves systemic endothelial vasoreactivity in patients with advanced heart failure.
Circulation 2001;104(25):3023-5.
2001: Hartmut Ruetten; Cornel Badorff; Christian Ihling; Andreas M Zeiher; Stefanie Dimmeler
Inhibition of caspase-3 improves contractile recovery of stunned myocardium, independent of apoptosis-inhibitory effects.
Journal of the American College of Cardiology 2001;38(7):2063-70.
2001: Jörg Hoffmann; Judith Haendeler; Andreas M Zeiher; Stefanie Dimmeler
TNFalpha and oxLDL reduce protein S-nitrosylation in endothelial cells.
The Journal of biological chemistry 2001;276(44):41383-7.
2001: Carmen Urbich; Z Mallat; A Tedgui; M Clauss; Andreas M Zeiher; Stefanie Dimmeler
Upregulation of TRAF-3 by shear stress blocks CD40-mediated endothelial activation.
The Journal of clinical investigation 2001;108(10):1451-8.
2001: Lothar Rössig; Jörg Hoffmann; Bénédicte Hugel; Z Mallat; A Haase; Jean-Marie Freyssinet; A Tedgui; Alexandra Aicher; Andreas M Zeiher; Stefanie Dimmeler
Vitamin C inhibits endothelial cell apoptosis in congestive heart failure.
Circulation 2001;104(18):2182-7.
2001: Jörg Hoffmann; Judith Haendeler; Alexandra Aicher; Lothar Rössig; Mariuca Vasa; Andreas M Zeiher; Stefanie Dimmeler
Aging enhances the sensitivity of endothelial cells toward apoptotic stimuli: important role of nitric oxide.
Circulation research 2001;89(8):709-15.
2001: F Jung; U Weiland; Roger Johns; Christian Ihling; Stefanie Dimmeler
Chronic hypoxia induces apoptosis in cardiac myocytes: a possible role for Bcl-2-like proteins.
Biochemical and biophysical research communications 2001;286(2):419-25.
2001: Stefanie Dimmeler; Alexandra Aicher; Mariuca Vasa; Christiane Mildner-Rihm; K Adler; M Tiemann; H Rütten; Stephan Fichtlscherer; Hans Martin; Andreas M Zeiher
HMG-CoA reductase inhibitors (statins) increase endothelial progenitor cells via the PI 3-kinase/Akt pathway.
The Journal of clinical investigation 2001;108(3):391-7.
2001: Lothar Rössig; A S Jadidi; Carmen Urbich; Cornel Badorff; Andreas M Zeiher; Stefanie Dimmeler
Akt-dependent phosphorylation of p21(Cip1) regulates PCNA binding and proliferation of endothelial cells.
Molecular and cellular biology 2001;21(16):5644-57.
2001: Kathrin S Michelsen; Alexandra Aicher; Mariette Mohaupt; Thomas Hartung; Stefanie Dimmeler; Carsten J Kirschning; Ralf R Schumann
The role of toll-like receptors (TLRs) in bacteria-induced maturation of murine dendritic cells (DCS). Peptidoglycan and lipoteichoic acid are inducers of DC maturation and require TLR2.
The Journal of biological chemistry 2001;276(28):25680-6.
2001: Mariuca Vasa; Stephan Fichtlscherer; Alexandra Aicher; K Adler; Carmen Urbich; Hans Martin; Andreas M Zeiher; Stefanie Dimmeler
Number and migratory activity of circulating endothelial progenitor cells inversely correlate with risk factors for coronary artery disease.
Circulation research 2001;89(1):E1-7.
2001: Mariuca Vasa; Stephan Fichtlscherer; K Adler; Alexandra Aicher; Hans Martin; Andreas M Zeiher; Stefanie Dimmeler
Increase in circulating endothelial progenitor cells by statin therapy in patients with stable coronary artery disease.
Circulation 2001;103(24):2885-90.
2001: Ingrid Fleming; Beate Fisslthaler; Stefanie Dimmeler; B E Kemp; Rudi Busse
Phosphorylation of Thr(495) regulates Ca(2+)/calmodulin-dependent endothelial nitric oxide synthase activity.
Circulation research 2001;88(11):E68-75.
2001: Emmanouil Chavakis; Elisabeth Dernbach; C Hermann; UF Mondorf; Andreas M Zeiher; Stefanie Dimmeler
Oxidized LDL inhibits vascular endothelial growth factor-induced endothelial cell migration by an inhibitory effect on the Akt/endothelial nitric oxide synthase pathway.
Circulation 2001;103(16):2102-7.
2001: Dirk H Walter; Volker Schächinger; M Elsner; S Mach; Stefanie Dimmeler; Wolfgang Auch-Schwelk; Andreas M Zeiher
Statin therapy is associated with reduced restenosis rates after coronary stent implantation in carriers of the Pl(A2)allele of the platelet glycoprotein IIIa gene.
European heart journal 2001;22(7):587-95.
2001: K Breitschopf; Andreas M Zeiher; Stefanie Dimmeler
Pro-atherogenic factors induce telomerase inactivation in endothelial cells through an Akt-dependent mechanism.
FEBS letters 2001;493(1):21-5.
2001: Lothar Rössig; Stefanie Dimmeler; Andreas M Zeiher
Apoptosis in the vascular wall and atherosclerosis.
Basic research in cardiology 2001;96(1):11-22.
2001: Volker Schächinger; Martina B Britten; Stefanie Dimmeler; Andreas M Zeiher
NADH/NADPH oxidase p22 phox gene polymorphism is associated with improved coronary endothelial vasodilator function.
European heart journal 2001;22(1):96-101.
2000: Lothar Rössig; Judith Haendeler; Z Mallat; Bénédicte Hugel; Jean-Marie Freyssinet; A Tedgui; Stefanie Dimmeler; Andreas M Zeiher
Congestive heart failure induces endothelial cell apoptosis: protective role of carvedilol.
Journal of the American College of Cardiology 2000;36(7):2081-9.
2000: Cornel Badorff; Birgit Fichtlscherer; Robert E Rhoads; Andreas M Zeiher; A Muelsch; Stefanie Dimmeler; Kirk U Knowlton
Nitric oxide inhibits dystrophin proteolysis by coxsackieviral protease 2A through S-nitrosylation: A protective mechanism against enteroviral cardiomyopathy.
Circulation 2000;102(18):2276-81.
2000: Carmen Urbich; Dirk H Walter; Andreas M Zeiher; Stefanie Dimmeler
Laminar shear stress upregulates integrin expression: role in endothelial cell adhesion and apoptosis.
Circulation research 2000;87(8):683-9.
2000: F Jung; Judith Haendeler; C Goebel; Andreas M Zeiher; Stefanie Dimmeler
Growth factor-induced phosphoinositide 3-OH kinase/Akt phosphorylation in smooth muscle cells: induction of cell proliferation and inhibition of cell death.
Cardiovascular research 2000;48(1):148-57.
2000: Mariuca Vasa; K Breitschopf; Andreas M Zeiher; Stefanie Dimmeler
Nitric oxide activates telomerase and delays endothelial cell senescence.
Circulation research 2000;87(7):540-2.
2000: Stefanie Dimmeler; Andreas M Zeiher
Endothelial cell apoptosis in angiogenesis and vessel regression.
Circulation research 2000;87(6):434-9.
2000: Stephan Fichtlscherer; G Rosenberger; Dirk H Walter; Susanne Breuer; Stefanie Dimmeler; Andreas M Zeiher
Elevated C-reactive protein levels and impaired endothelial vasoreactivity in patients with coronary artery disease.
Circulation 2000;102(9):1000-6.
2000: Lothar Rössig; Judith Haendeler; Corinna Hermann; P Malchow; Carmen Urbich; Andreas M Zeiher; Stefanie Dimmeler
Nitric oxide down-regulates MKP-3 mRNA levels: involvement in endothelial cell protection from apoptosis.
The Journal of biological chemistry 2000;275(33):25502-7.
2000: Stefanie Dimmeler; Elisabeth Dernbach; Andreas M Zeiher
Phosphorylation of the endothelial nitric oxide synthase at ser-1177 is required for VEGF-induced endothelial cell migration.
FEBS letters 2000;477(3):258-62.
2000: K Breitschopf; Andreas M Zeiher; Stefanie Dimmeler
Ubiquitin-mediated degradation of the proapoptotic active form of bid. A functional consequence on apoptosis induction.
The Journal of biological chemistry 2000;275(28):21648-52.
2000: K Breitschopf; Judith Haendeler; P Malchow; Andreas M Zeiher; Stefanie Dimmeler
Posttranslational modification of Bcl-2 facilitates its proteasome-dependent degradation: molecular characterization of the involved signaling pathway.
Molecular and cellular biology 2000;20(5):1886-96.
2000: U Weiland; Judith Haendeler; Christian Ihling; Udo Albus; W Scholz; Hartmut Ruetten; Andreas M Zeiher; Stefanie Dimmeler
Inhibition of endogenous nitric oxide synthase potentiates ischemia-reperfusion-induced myocardial apoptosis via a caspase-3 dependent pathway.
Cardiovascular research 2000;45(3):671-8.
2000: Corinna Hermann; Birgit Assmus; Carmen Urbich; Andreas M Zeiher; Stefanie Dimmeler
Insulin-mediated stimulation of protein kinase Akt: A potent survival signaling cascade for endothelial cells.
Arteriosclerosis, thrombosis, and vascular biology 2000;20(2):402-9.
2000: Carmen Urbich; M Fritzenwanger; Andreas M Zeiher; Stefanie Dimmeler
Laminar shear stress upregulates the complement-inhibitory protein clusterin : a novel potent defense mechanism against complement-induced endothelial cell activation.
Circulation 2000;101(4):352-5.
1999: Stefanie Dimmeler; Andreas M Zeiher
Nitric oxide-an endothelial cell survival factor.
Cell death and differentiation 1999;6(10):964-8.
1999: Stefanie Dimmeler; K Breitschopf; Judith Haendeler; Andreas M Zeiher
Dephosphorylation targets Bcl-2 for ubiquitin-dependent degradation: a link between the apoptosome and the proteasome pathway.
The Journal of experimental medicine 1999;189(11):1815-22.
1999: Lothar Rössig; Birgit Fichtlscherer; K Breitschopf; Judith Haendeler; Andreas M Zeiher; Alexander Mülsch; Stefanie Dimmeler
Nitric oxide inhibits caspase-3 by S-nitrosation in vivo.
The Journal of biological chemistry 1999;274(11):6823-6.
1999: Stefanie Dimmeler; Corinna Hermann; J Galle; Andreas M Zeiher
Upregulation of superoxide dismutase and nitric oxide synthase mediates the apoptosis-suppressive effects of shear stress on endothelial cells.
Arteriosclerosis, thrombosis, and vascular biology 1999;19(3):656-64.
1999: Judith Haendeler; Andreas M Zeiher; Stefanie Dimmeler
Nitric oxide and apoptosis.
Vitamins and hormones 1999;57():49-77.
1998: Stefanie Dimmeler; Corinna Hermann; Andreas M Zeiher
Apoptosis of endothelial cells. Contribution to the pathophysiology of atherosclerosis?
European cytokine network 1998;9(4):697-8.
1998: Dirk H Walter; Judith Haendeler; J Galle; Andreas M Zeiher; Stefanie Dimmeler
Cyclosporin A inhibits apoptosis of human endothelial cells by preventing release of cytochrome C from mitochondria.
Circulation 1998;98(12):1153-7.
1998: Stefanie Dimmeler; Birgit Assmus; Corinna Hermann; Judith Haendeler; Andreas M Zeiher
Fluid shear stress stimulates phosphorylation of Akt in human endothelial cells: involvement in suppression of apoptosis.
Circulation research 1998;83(3):334-41.
1998: Stefanie Dimmeler; Judith Haendeler; A Sause; Andreas M Zeiher
Nitric oxide inhibits APO-1/Fas-mediated cell death.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1998;9(5):415-22.
1997: Corinna Hermann; Andreas M Zeiher; Stefanie Dimmeler
Shear stress inhibits H2O2-induced apoptosis of human endothelial cells by modulation of the glutathione redox cycle and nitric oxide synthase.
Arteriosclerosis, thrombosis, and vascular biology 1997;17(12):3588-92.
1997: Stefanie Dimmeler; V Rippmann; U Weiland; Judith Haendeler; Andreas M Zeiher
Angiotensin II induces apoptosis of human endothelial cells. Protective effect of nitric oxide.
Circulation research 1997;81(6):970-6.
1997: Dirk H Walter; Volker Schächinger; M Elsner; Stefanie Dimmeler; Andreas M Zeiher
Platelet glycoprotein IIIa polymorphisms and risk of coronary stent thrombosis.
Lancet 1997;350(9086):1217-9.
1997: Judith Haendeler; U Weiland; Andreas M Zeiher; Stefanie Dimmeler
Effects of redox-related congeners of NO on apoptosis and caspase-3 activity.
Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society 1997;1(4):282-93.
1997: Stefanie Dimmeler; Andreas M Zeiher
Nitric oxide and apoptosis: another paradigm for the double-edged role of nitric oxide.
Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society 1997;1(4):275-81.
1997: Stefanie Dimmeler; Judith Haendeler; J Galle; Andreas M Zeiher
Oxidized low-density lipoprotein induces apoptosis of human endothelial cells by activation of CPP32-like proteases. A mechanistic clue to the 'response to injury' hypothesis.
Circulation 1997;95(7):1760-3.
1997: Stefanie Dimmeler; Judith Haendeler; M Nehls; Andreas M Zeiher
Suppression of apoptosis by nitric oxide via inhibition of interleukin-1beta-converting enzyme (ICE)-like and cysteine protease protein (CPP)-32-like proteases.
The Journal of experimental medicine 1997;185(4):601-7.
1996: Judith Haendeler; Andreas M Zeiher; Stefanie Dimmeler
Vitamin C and E prevent lipopolysaccharide-induced apoptosis in human endothelial cells by modulation of Bcl-2 and Bax.
European journal of pharmacology 1996;317(2-3):407-11.
1996: Stefanie Dimmeler; Judith Haendeler; V Rippmann; M Nehls; Andreas M Zeiher
Shear stress inhibits apoptosis of human endothelial cells.
FEBS letters 1996;399(1-2):71-4.
1996: Judith Haendeler; U K Messmer; B Brüne; Edmund A M Neugebauer; Stefanie Dimmeler
Endotoxic shock leads to apoptosis in vivo and reduces Bcl-2.
Shock (Augusta, Ga.) 1996;6(6):405-9.
1996: Stefanie Dimmeler; C K Kum; C Troost; M Auweiler; A Lechleuthner; Manfred Nagelschmidt; Edmund A M Neugebauer
H1-antagonism improves intestinal mucosal pH and heart function in porcine hypodynamic endotoxic shock.
Shock (Augusta, Ga.) 1996;5(3):213-6.
1996: Wolfgang Grellner; Burkhard Madea; J P Kruppenbacher; Stefanie Dimmeler
Interleukin-1 alpha (IL-1 alpha) and N-formyl-methionyl-leucyl-phenylalanine (FMLP) as potential inducers of supravital chemotaxis.
International journal of legal medicine 1996;109(3):130-3.
1995: Stefanie Dimmeler; S Brinkmann; E Neugebauer
Endotoxin-induced changes of endothelial cell viability and permeability: protective effect of a 21-aminosteroid.
European journal of pharmacology 1995;287(3):257-61.
1995: Stefanie Dimmeler; A Lechleuthner; M Auweiler; C Troost; Manfred Nagelschmidt; Edmund A M Neugebauer
Effect of H1-antagonism on cardiovascular, pulmonary, and immunological dysfunction in porcine endotoxic shock.
Shock (Augusta, Ga.) 1995;3(6):416-21.
1995: Edmund A M Neugebauer; Stefanie Dimmeler; Hans Troidl
[Mediator systems and infection].
Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen 1995;66(1):2-10.
1994: Bertil Bouillon; M Krämer; T Paffrath; Stefanie Dimmeler; Edmund A M Neugebauer; Thomas Tiling
[Quality assurance in the management of severely ill patients: how can score systems help?].
Der Unfallchirurg 1994;97(4):191-8.
1994: Stefanie Dimmeler; U K Messmer; Gisa Tiegs; Bernhard Brüne
Modulation of glyceraldehyde-3-phosphate dehydrogenase in Salmonella abortus equi lipopolysaccharide-treated mice.
European journal of pharmacology 1994;267(1):105-12.
1994: Bernhard Brüne; Stefanie Dimmeler; L Molina y Vedia; E G Lapetina
Nitric oxide: a signal for ADP-ribosylation of proteins.
Life sciences 1994;54(2):61-70.
1993: Edmund A M Neugebauer; Stefanie Dimmeler
[Pathophysiology of anaphylaxis].
Anästhesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS 1993;28(5):303-6.
1993: Stefanie Dimmeler; M Ankarcrona; Pierluigi Nicotera; Bernhard Brüne
Exogenous nitric oxide (NO) generation or IL-1 beta-induced intracellular NO production stimulates inhibitory auto-ADP-ribosylation of glyceraldehyde-3-phosphate dehydrogenase in RINm5F cells.
Journal of immunology (Baltimore, Md. : 1950) 1993;150(7):2964-71.
1993: Stefanie Dimmeler; Bernhard Brüne
Nitric oxide preferentially stimulates auto-ADP-ribosylation of glyceraldehyde-3-phosphate dehydrogenase compared to alcohol or lactate dehydrogenase.
FEBS letters 1993;315(1):21-4.
1992: Stefanie Dimmeler; Bernhard Brüne
Characterization of a nitric-oxide-catalysed ADP-ribosylation of glyceraldehyde-3-phosphate dehydrogenase.
European journal of biochemistry / FEBS 1992;210(1):305-10.
1992: Stefanie Dimmeler; Friedrich Lottspeich; Bernhard Brüne
Nitric oxide causes ADP-ribosylation and inhibition of glyceraldehyde-3-phosphate dehydrogenase.
The Journal of biological chemistry 1992;267(24):16771-4.
1992: Bernhard Brüne; Stefanie Dimmeler; E G Lapetina
NADPH: a stimulatory cofactor for nitric oxide-induced ADP-ribosylation reaction.
Biochemical and biophysical research communications 1992;182(3):1166-71.
1991: Stefanie Dimmeler; Bernhard Brüne
L-arginine stimulates an endogenous ADP-ribosyltransferase.
Biochemical and biophysical research communications 1991;178(3):848-55.
1991: Stefanie Dimmeler; B Brüne; Volker Ullrich
Ebselen prevents inositol (1,4,5)-trisphosphate binding to its receptor.
Biochemical pharmacology 1991;42(5):1151-3.