FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Jian Ding

Research Profile

Anatomy

Living Beings

Mouse

Chemicals & Drugs

Physiology

Disorders

Co-author Network

Publications

TOP 3
Yongjun Mao; Jingkang Shen; Jian Ding; Xiaoguang Kong; Nicholas Kenneth Terrett; Zhen Wang; Hua Xie; Wenxiu Zhu; Jingshan Shen
Design, synthesis and biological evaluation of novel pyrimidine, 3-cyanopyridine and m-amino-N-phenylbenzamide based monocyclic EGFR tyrosine kinase inhibitors.
Na Ye; Chuan-Huizi Chen; Tiantian Chen; Yi Chen; Jian Ding; Jin-Xue He; Xia-Juan Huan; Qiufeng Liu; Ze-Hong Miao; Shan-Shan Song; Zilan Song; Yechun Xu; Ao Zhang
Design, synthesis, and biological evaluation of a series of benzo[de][1,7]naphthyridin-7(8H)-ones bearing a functionalized longer chain appendage as novel PARP1 inhibitors.
Shi-Hui Dong; Ying-Zi Ge; Jia Liu; Cheng-Hui Xu; Jian Ding; Lei Dong; Jian-Min Yue
Chemical constituents from Brucea javanica.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Jian Ding (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Yongjun Mao; Jingkang Shen; Jian Ding; Xiaoguang Kong; Nicholas Kenneth Terrett; Zhen Wang; Hua Xie; Wenxiu Zhu; Jingshan Shen
Design, synthesis and biological evaluation of novel pyrimidine, 3-cyanopyridine and m-amino-N-phenylbenzamide based monocyclic EGFR tyrosine kinase inhibitors.
Bioorganic & medicinal chemistry 2013;21(11):3090-104.
2013: Na Ye; Chuan-Huizi Chen; Tiantian Chen; Yi Chen; Jian Ding; Jin-Xue He; Xia-Juan Huan; Qiufeng Liu; Ze-Hong Miao; Shan-Shan Song; Zilan Song; Yechun Xu; Ao Zhang
Design, synthesis, and biological evaluation of a series of benzo[de][1,7]naphthyridin-7(8H)-ones bearing a functionalized longer chain appendage as novel PARP1 inhibitors.
Journal of medicinal chemistry 2013;56(7):2885-903.
2013: Shi-Hui Dong; Ying-Zi Ge; Jia Liu; Cheng-Hui Xu; Jian Ding; Lei Dong; Jian-Min Yue
Chemical constituents from Brucea javanica.
Phytochemistry 2013;85():175-84.
2012: Jian-Ming Feng; Yi-Ran Huang; Yi Jiang; Jia-Xin Li; Ze-Hong Miao; Lin-Jiang Tong; Jin Zhang; Yi Chen; Jian Ding
Characterization of the conversion between CD133+ and CD133- cells in colon cancer SW620 cell line.
Cancer biology & therapy 2012;13(14):1396-406.
2012: Li-Fan Zeng; Yong-Tang Zheng; Bikash Debnath; Jian Ding; Roza Kazemi; Nouri Neamati; Srinivas Odde; Tino W Sanchez; Yong Wang; Hua Xie; Shili Xu; Zhong-Liang Xu; Liu-Meng Yang; Ya-Qiu Long
Repositioning HIV-1 integrase inhibitors for cancer therapeutics: 1,6-naphthyridine-7-carboxamide as a promising scaffold with drug-like properties.
Journal of medicinal chemistry 2012;55(22):9492-509.
2012: Stefano Giustino Manzo; Jessica Marinello; Ying-Qing Wang; Zhao-Li Zhou; Giovanni Capranico; Jian Ding; Jin-Xue He; Yuan-Chao Li; Ze-Hong Miao
Natural product triptolide mediates cancer cell death by triggering CDK7-dependent degradation of RNA polymerase II.
Cancer research 2012;72(20):5363-73.
2012: Yuanfeng Zhou; Yi Chen; Meiyu Geng; Hualiang Jiang; Liping Lin; Cheng Luo; Yanyan Shen; Linjiang Tong; Yuanyuan Wang; Weiwei Wen; Yong Xi; Hua Xie; Jie Zhang; Jian Ding
AL3810, a multi-tyrosine kinase inhibitor, exhibits potent anti-angiogenic and anti-tumour activity via targeting VEGFR, FGFR and PDGFR.
Journal of cellular and molecular medicine 2012;16(10):2321-30.
2012: Sheng-Ping Yang; Xiao-Wei Zhang; Jing Ai; Jian Ding; Li-She Gan; Mei-Yu Geng; Zu-Shang Su; Lu Wang; Ying Wang; Jin-Biao Xu; Jian-Min Yue
Potent HGF/c-Met axis inhibitors from Eucalyptus globulus: the coupling of phloroglucinol and sesquiterpenoid is essential for the activity.
Journal of medicinal chemistry 2012;55(18):8183-7.
2012: Ze-Hong Miao; Jian-ming Feng; Jian Ding
Newly discovered angiogenesis inhibitors and their mechanisms of action.
Acta pharmacologica Sinica 2012;33(9):1103-11.
2012: Bing Yu; Jian-Min Yue; Wei Wang; Ying-Qing Wang; Sheng-Ping Yang; Jian Ding; Yi Jiang; Mei-Hong Li; Ze-Hong Miao
Pseudolaric acid B-driven phosphorylation of c-Jun impairs its role in stabilizing HIF-1alpha: a novel function-converter model.
Journal of molecular medicine (Berlin, Germany) 2012;90(8):971-81.
2012: Si-meng Chen; Jian Ding; Chris Liang; Jia-li Liu; Xiang Wang; Ling-Hua Meng
Inhibition of tumor cell growth, proliferation and migration by X-387, a novel active-site inhibitor of mTOR.
Biochemical pharmacology 2012;83(9):1183-94.
2012: Hong-Bing Liu; Cheng-Hui Xu; Jin-Hai Yu; Jian Ding; Hua Zhang; Jian-Min Yue
Cytotoxic diterpenoids from Sapium insigne.
Journal of natural products 2012;75(4):722-7.
2012: Zhao-Li Zhou; Ya-Xi Yang; Jian Ding; Yuan-Chao Li; Ze-Hong Miao
Triptolide: structural modifications, structure-activity relationships, bioactivities, clinical development and mechanisms.
Natural product reports 2012;29(4):457-75.
2012: Shuai Wang; Xianliang Xin; Yiming Yang; Wengang Chai; Jian Ding; Min Huang; Xun Huang; Hualiang Jiang; Zhongjie Liang; Cheng Luo; Qiuming Pan; Shuying Peng; Danni Sun; Meiyu Geng
Extensive crosstalk between O-GlcNAcylation and phosphorylation regulates Akt signaling.
PloS one 2012;7(5):e37427.
2011: Qing Yu; Yong-Long Chi; Jian Ding; Zhong-Ke Lin; Tao Wang; Wei-Yang Gao
Functional motor nerve regeneration without motor-sensory specificity following end-to-side neurorrhaphy: an experimental study.
The Journal of hand surgery 2011;36(12):2010-6.
2011: Yu-Qin Wang; Yu-Yuan Xie; Yi Chen; Jian Ding; Qian He; Xiao-Hua Li; Ze-Hong Miao; Chun-Hao Yang
Design, synthesis and biological evaluation of substituted 11H-benzo[a]carbazole-5-carboxamides as novel antitumor agents.
European journal of medicinal chemistry 2011;46(12):5878-84.
2011: Jin-Jian Lu; Si-Meng Chen; Jian Ding; Xiao-Wei Zhang; Ling-Hua Meng
The anti-cancer activity of dihydroartemisinin is associated with induction of iron-dependent endoplasmic reticulum stress in colorectal carcinoma HCT116 cells.
Investigational new drugs 2011;29(6):1276-83.
2011: Jing Ai; Yi Chen; Jennifer Daugherty-Holtrop; Jian Ding; Jia Fan; Teng Feng; Xin Gao; Yuanzheng He; Min Huang; Jing Li; Qiuming Pan; Qingjuan Tang; Yanlin Wu; H Eric Xu; Siyun Xu; Yang Xu; Xihua Yue; Ruiyu Zhou; Qingfeng Zhu; Meiyu Geng
The role of polymeric immunoglobulin receptor in inflammation-induced tumor metastasis of human hepatocellular carcinoma.
Journal of the National Cancer Institute 2011;103(22):1696-712.
2011: Jin-gui Ma; Xian-liang Xin; Si-meng Chen; Yi Chen; Jian Ding; He Huang; Li-Ping Lin; Hong Liu; Ling-Hua Meng
PH006, a novel and selective Src kinase inhibitor, suppresses human breast cancer growth and metastasis in vitro and in vivo.
Breast cancer research and treatment 2011;130(1):85-96.
2011: Min Gui; Min Huang; Ming Li; Ying-Xia Li; Chun-Hong Liu; Da-Kuo Shi; Qi-Ming Sun; Jing Zhang; Yu Zhao; Qin Chen; Jian-Ming Feng; Meiyu Geng; Jian Ding
D11, a novel glycosylated diphyllin derivative, exhibits potent anticancer activity by targeting topoisomerase IIα.
Investigational new drugs 2011;29(5):800-10.
2011: Jin-Jian Lu; Yu-Jun Cai; Jian Ding
Curcumin induces DNA damage and caffeine-insensitive cell cycle arrest in colorectal carcinoma HCT116 cells.
Molecular and cellular biochemistry 2011;354(1-2):247-52.
2011: Yi Jiang; Hong-Chun Liu; Ze-Hong Miao; Lin-Jiang Tong; Yi Wang; Lei Xu; Bing Yu; Zhao-Li Zhou; Yi Chen; Jing-Xu Gong; Yue-Wei Guo; Jian Ding
Drug transporter-independent liver cancer cell killing by a marine steroid methyl spongoate via apoptosis induction.
The Journal of biological chemistry 2011;286(30):26461-9.
2011: Zhixiang Zhang; Tao Meng; Na Yang; Wei Wang; Bing Xiong; Yi Chen; Lanping Ma; Jingkang Shen; Ze-Hong Miao; Jian Ding
MT119, a new planar-structured compound, targets the colchicine site of tubulin arresting mitosis and inhibiting tumor cell proliferation.
International journal of cancer. Journal international du cancer 2011;129(1):214-24.
2011: Shi-Hui Dong; Chuan-Rui Zhang; Cheng-Hui Xu; Jian Ding; Jian-Min Yue
Daphnane-type diterpenoids from Trigonostemon howii.
Journal of natural products 2011;74(5):1255-61.
2011: Caihua Zhu; Qin Chen; Zuoquan Xie; Jing Ai; Linjiang Tong; Jian Ding; Meiyu Geng
The role of histone deacetylase 7 (HDAC7) in cancer cell proliferation: regulation on c-Myc.
Journal of molecular medicine (Berlin, Germany) 2011;89(3):279-89.
2011: Hua Xie; Yang Yang; Xiaowei Zhang; Mingyue Zheng; Jianping Zuo; Yi Chen; Zhuo Chen; Meiyu Geng; Hualiang Jiang; Xiaoyan Jiang; Yong Jiang; Liping Lin; Wenchao Qu; Xiaowei Ren; Linjiang Tong; Hua Wan; Jian Ding
AST1306, a novel irreversible inhibitor of the epidermal growth factor receptor 1 and 2, exhibits antitumor activity both in vitro and in vivo.
PloS one 2011;6(7):e21487.
2010: Zhixiang Zhang; Tao Meng; Jingxue He; Ming Li; Lin-Jiang Tong; Bing Xiong; Liping Lin; Jingkang Shen; Ze-Hong Miao; Jian Ding
MT7, a novel compound from a combinatorial library, arrests mitosis via inhibiting the polymerization of microtubules.
Investigational new drugs 2010;28(6):715-28.
2010: Bing Zhou; Zehong Miao; Gang Deng; Jian Ding; Yaxi Yang; Huijin Feng; Yuanchao Li
Synthesis and biological evaluation of novel triptolide analogues for anticancer activity.
Bioorganic & medicinal chemistry letters 2010;20(21):6217-21.
2010: Ting Li; Jia Bei Wang; Xiang Wang; Na Yang; Si-Meng Chen; Lin-Jiang Tong; Chun-Hao Yang; Ling-Hua Meng; Jian Ding
WJD008, a dual phosphatidylinositol 3-kinase (PI3K)/mammalian target of rapamycin inhibitor, prevents PI3K signaling and inhibits the proliferation of transformed cells with oncogenic PI3K mutant.
The Journal of pharmacology and experimental therapeutics 2010;334(3):830-8.
2010: Guang Chen; Na Yang; Xiang Wang; Si-Yuan Zheng; Yi Chen; Lin-Jiang Tong; Yi-Xue Li; Ling-Hua Meng; Jian Ding
Identification of p27/KIP1 expression level as a candidate biomarker of response to rapalogs therapy in human cancer.
Journal of molecular medicine (Berlin, Germany) 2010;88(9):941-52.
2010: Mei Dai; Ze-Hong Miao; Xuan Ren; Lin-Jiang Tong; Na Yang; Ting Li; Li-Ping Lin; Yue-Mao Shen; Jian Ding
MFTZ-1 reduces constitutive and inducible HIF-1α accumulation and VEGF secretion independent of its topoisomerase II inhibition.
Journal of cellular and molecular medicine 2010;14(9):2281-91.
2010: He Huang; Jingui Ma; Jianmei Shi; Linghua Meng; Hualiang Jiang; Jian Ding; Hong Liu
Discovery of novel purine derivatives with potent and selective inhibitory activity against c-Src tyrosine kinase.
Bioorganic & medicinal chemistry 2010;18(13):4615-24.
2010: Jin-Jian Lu; Ling-Hua Meng; Uma Shankavaram; Cai-Hua Zhu; Lin-Jiang Tong; Guang Chen; Li-Ping Lin; John N Weinstein; Jian Ding
Dihydroartemisinin accelerates c-MYC oncoprotein degradation and induces apoptosis in c-MYC-overexpressing tumor cells.
Biochemical pharmacology 2010;80(1):22-30.
2010: He Huang; Qin Chen; Xin Ku; Linghua Meng; Liping Lin; Xiang Wang; Caihua Zhu; Yi Wang; Zhi Chen; Ming Li; Hualiang Jiang; Kaixian Chen; Jian Ding; Hong Liu
A series of alpha-heterocyclic carboxaldehyde thiosemicarbazones inhibit topoisomerase IIalpha catalytic activity.
Journal of medicinal chemistry 2010;53(8):3048-64.
2010: Xiaofeng Liu; Hua Xie; Cheng Luo; Linjiang Tong; Yi Wang; Ting Peng; Jian Ding; Hualiang Jiang; Honglin Li
Discovery and SAR of thiazolidine-2,4-dione analogues as insulin-like growth factor-1 receptor (IGF-1R) inhibitors via hierarchical virtual screening.
Journal of medicinal chemistry 2010;53(6):2661-5.
2010: Jing Zhang; Yi Chen; Xian-liang Xin; Qiu-ning Li; Ming Li; Li-Ping Lin; Mei-yu Geng; Jian Ding
Oligomannurarate sulfate blocks tumor growth by inhibiting NF-kappaB activation.
Acta pharmacologica Sinica 2010;31(3):375-81.
2010: Si-Meng Chen; Ling-Hua Meng; Jian Ding
New microtubule-inhibiting anticancer agents.
Expert opinion on investigational drugs 2010;19(3):329-43.
2010: Zhao-Li Zhou; Zhi-Guo Luo; Bing Yu; Yi Jiang; Yi Chen; Jian-Ming Feng; Mei Dai; Lin-Jiang Tong; Zheng Li; Yuan-Chao Li; Jian Ding; Ze-Hong Miao
Increased accumulation of hypoxia-inducible factor-1α with reduced transcriptional activity mediates the antitumor effect of triptolide.
Molecular cancer 2010;9():268.
2009: Hong Zhu; Ze-Hong Miao; Min Huang; Jian-Ming Feng; Zhi-Xiang Zhang; Jin-Jian Lu; Yu-Jun Cai; Lin-Jiang Tong; Yu-Fang Xu; Xu-Hong Qian; Jian Ding
Naphthalimides induce G(2) arrest through the ATM-activated Chk2-executed pathway in HCT116 cells.
Neoplasia (New York, N.Y.) 2009;11(11):1226-34.
2009: Bing Yu; Ze-Hong Miao; Yi Jiang; Mei-Hong Li; Na Yang; Ting Li; Jian Ding
c-Jun protects hypoxia-inducible factor-1alpha from degradation via its oxygen-dependent degradation domain in a nontranscriptional manner.
Cancer research 2009;69(19):7704-12.
2009: Min Jiang; Ting Li; Linghua Meng; Chunhao Yang; Yuyuan Xie; Jian Ding
Direct palladium-catalyzed arylations of aryl bromides with 2/9-substituted pyrimido[5,4-b]indolizines.
Journal of combinatorial chemistry 2009;11(5):806-8.
2009: Qiu-Ning Li; Hai-Ying Liu; Xian-Liang Xin; Qiu-Ming Pan; Lu Wang; Jing Zhang; Qin Chen; Mei-Yu Geng; Jian Ding
Marine-derived oligosaccharide sulfate (JG3) suppresses heparanase-driven cell adhesion events in heparanase over-expressing CHO-K1 cells.
Acta pharmacologica Sinica 2009;30(7):1033-8.
2009: He Huang; Qi Jia; Jingui Ma; Guangrong Qin; Yingyi Chen; Yonghua Xi; Liping Lin; Weiliang Zhu; Jian Ding; Hualiang Jiang; Hong Liu
Discovering novel quercetin-3-O-amino acid-esters as a new class of Src tyrosine kinase inhibitors.
European journal of medicinal chemistry 2009;44(5):1982-8.
2009: Xuan Ren; Mei Dai; Li-Ping Lin; Pui-Kai Li; Jian Ding
Anti-angiogenic and vascular disrupting effects of C9, a new microtubule-depolymerizing agent.
British journal of pharmacology 2009;156(8):1228-38.
2009: Chao Zhang; Na Yang; Chun-Hao Yang; Hua-Sheng Ding; Cheng Luo; Yu Zhang; Mao-Jiang Wu; Xiong-Wen Zhang; Xu Shen; Hua-Liang Jiang; Ling-Hua Meng; Jian Ding
S9, a novel anticancer agent, exerts its anti-proliferative activity by interfering with both PI3K-Akt-mTOR signaling and microtubule cytoskeleton.
PloS one 2009;4(3):e4881.
2008: Hongwen Tao; Xiaojiang Hao; Jinggen Liu; Jian Ding; Yuchun Fang; Qianqun Gu; Weiming Zhu
Resin glycoside constituents of Ipomoea pes-caprae (beach morning glory).
Journal of natural products 2008;71(12):1998-2003.
2008: Hai-hong Li; He Huang; Xiu-hua Zhang; Xiao-Min Luo; Li-Ping Lin; Hua-Liang Jiang; Jian Ding; Kai-xian Chen; Hong Liu
Discovering novel 3-nitroquinolines as a new class of anticancer agents.
Acta pharmacologica Sinica 2008;29(12):1529-38.
2008: Jian-Ming Feng; Hong Zhu; Xiao-Wei Zhang; Jian Ding; Ze-Hong Miao
Proteasome-dependent degradation of Chk1 kinase induced by the topoisomerase II inhibitor R16 contributes to its anticancer activity.
Cancer biology & therapy 2008;7(11):1726-31.
2008: Yu-Jun Cai; Jin-Jian Lu; Hong Zhu; Hua Xie; Min Huang; Li-Ping Lin; Xiong-Wen Zhang; Jian Ding
Salvicine triggers DNA double-strand breaks and apoptosis by GSH-depletion-driven H2O2 generation and topoisomerase II inhibition.
Free radical biology & medicine 2008;45(5):627-35.
2008: Zu-Shang Su; Sheng Yin; Zhi-Wang Zhou; Yan Wu; Jian Ding; Jian-Min Yue
Sesquiterpenoids from Hedyosmum orientale.
Journal of natural products 2008;71(8):1410-3.
2008: Jin-Jian Lu; Ling-Hua Meng; Yu-Jun Cai; Qin Chen; Lin-Jiang Tong; Li-Ping Lin; Jian Ding
Dihydroartemisinin induces apoptosis in HL-60 leukemia cells dependent of iron and p38 mitogen-activated protein kinase activation but independent of reactive oxygen species.
Cancer biology & therapy 2008;7(7):1017-23.
2008: Min Huang; Ze-Hong Miao; Hong Zhu; Yu-Jun Cai; Wei Lu; Jian Ding
Chk1 and Chk2 are differentially involved in homologous recombination repair and cell cycle arrest in response to DNA double-strand breaks induced by camptothecins.
Molecular cancer therapeutics 2008;7(6):1440-9.
2008: Jun Huo; Sheng-Ping Yang; Bo-Jun Xie; Shang-Gao Liao; Li-Ping Lin; Jian Ding; Jian-Min Yue
Cytotoxic sesquiterpenoids from Vernonia bockiana.
Journal of Asian natural products research 2008;10(5-6):571-5.
2008: Yong-Wei Zhang; Zhi-Xiang Zhang; Ze-Hong Miao; Jian Ding
The telomeric protein TRF2 is critical for the protection of A549 cells from both telomere erosion and DNA double-strand breaks driven by salvicine.
Molecular pharmacology 2008;73(3):824-32.
2008: Jin Zhou; Yi Chen; Jing-Yu Lang; Jin-Jian Lu; Jian Ding
Salvicine inactivates beta 1 integrin and inhibits adhesion of MDA-MB-435 cells to fibronectin via reactive oxygen species signaling.
Molecular cancer research : MCR 2008;6(2):194-204.
2008: Juan-juan Chen; Xiao-yu Su; Xiao-dong Xi; Li-Ping Lin; Jian Ding; He Lu
Fibrinogen interaction of CHO cells expressing chimeric alphaIIb/alphavbeta3 integrin.
Acta pharmacologica Sinica 2008;29(2):204-10.
2008: Ying Shen; Yong-Wei Zhang; Zhi-Xiang Zhang; Ze-Hong Miao; Jian Ding
hTERT-targeted RNA interference inhibits tumorigenicity and motility of HCT116 cells.
Cancer biology & therapy 2008;7(2):228-36.
2008: Sheng-Ping Yang; Yu-Jun Cai; Bang-le Zhang; Lin-Jiang Tong; Hua Xie; Yan Wu; Li-Ping Lin; Jian Ding; Jian-Min Yue
Structural modification of an angiogenesis inhibitor discovered from traditional Chinese medicine and a structure-activity relationship study.
Journal of medicinal chemistry 2008;51(1):77-85.
2008: Jingui Ma; Xianliang Xin; Linghua Meng; Linjiang Tong; Liping Lin; Meiyu Geng; Jian Ding
The marine-derived oligosaccharide sulfate (MdOS), a novel multiple tyrosine kinase inhibitor, combats tumor angiogenesis both in vitro and in vivo.
PloS one 2008;3(11):e3774.
2008: Qin Chen; Ling-Hua Meng; Cai-Hua Zhu; Li-Ping Lin; He Lu; Jian Ding
ADAM15 suppresses cell motility by driving integrin alpha5beta1 cell surface expression via Erk inactivation.
The international journal of biochemistry & cell biology 2008;40(10):2164-73.
2007: Sheng Yin; Jun-Juan Xue; Cheng-Qi Fan; Ze-Hong Miao; Jian Ding; Jian-Min Yue
Eucalyptals A-C with a new skeleton isolated from Eucalyptus globulus.
Organic letters 2007;9(26):5549-52.
2007: Yujun Cai; Jinjian Lu; Zehong Miao; Liping Lin; Jian Ding
Reactive oxygen species contribute to cell killing and P-glycoprotein downregulation by salvicine in multidrug resistant K562/A02 cells.
Cancer biology & therapy 2007;6(11):1794-9.
2007: Cheng-Ying Xie; Hong Zhu; Li-Ping Lin; Ze-Hong Miao; Meiyu Geng; Yu-Jun Cai; Yi Chen; Hua-Jun Zhao; Hai-Bin Luo; Xiong-Wen Zhang; Li-Ming Fan; Yue-Mao Shen; Jian Ding
MFTZ-1, an actinomycetes subspecies derived antitumor macrolide, functions as a novel topoisomerase II poison.
Molecular cancer therapeutics 2007;6(11):3059-70.
2007: Xiu-Hua Zhang; Xiao-Ning Guo; Li Zhong; Xiao-Min Luo; Hua-Liang Jiang; Li-Ping Lin; Jian Ding
Establishment of the active catalytic domain of human PDGFRbeta tyrosine kinase-based ELISA assay for inhibitor screening.
Biochimica et biophysica acta 2007;1770(10):1490-7.
2007: Yuxin Qin; Linghua Meng; Chaoxin Hu; Wenhu Duan; Zhili Zuo; Liping Lin; Xiongwen Zhang; Jian Ding
Gambogic acid inhibits the catalytic activity of human topoisomerase IIalpha by binding to its ATPase domain.
Molecular cancer therapeutics 2007;6(9):2429-40.
2007: Ling-Hua Meng; Jian Ding
Salvicine, a novel topoisomerase II inhibitor, exerts its potent anticancer activity by ROS generation.
Acta pharmacologica Sinica 2007;28(9):1460-5.
2007: Fang Tian; Cai-hua Zhu; Xiong-Wen Zhang; Xin Xie; Xian-liang Xin; Yang-Hua Yi; Li-Ping Lin; Meiyu Geng; Jian Ding
Philinopside E, a new sulfated saponin from sea cucumber, blocks the interaction between kinase insert domain-containing receptor (KDR) and alphavbeta3 integrin via binding to the extracellular domain of KDR.
Molecular pharmacology 2007;72(3):545-52.
2007: Sheng Yin; Xiao-Ning Wang; Cheng-Qi Fan; Li-Ping Lin; Jian Ding; Jian-Min Yue
Limonoids from the seeds of the marine mangrove Xylocarpus granatum.
Journal of natural products 2007;70(4):682-5.
2007: Min Huang; Heyong Gao; Yi Chen; Hong Zhu; Yujun Cai; Xiongwen Zhang; Zehong Miao; Hualiang Jiang; Jian Zhang; Hongwu Shen; Liping Lin; Wei Lu; Jian Ding
Chimmitecan, a novel 9-substituted camptothecin, with improved anticancer pharmacologic profiles in vitro and in vivo.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(4):1298-307.
2007: Hong Zhu; Min Huang; Fan Yang; Yi Chen; Ze-Hong Miao; Xu-Hong Qian; Yu-Fang Xu; Yu-Xin Qin; Hai-Bin Luo; Xu Shen; Meiyu Geng; Yu-Jun Cai; Jian Ding
R16, a novel amonafide analogue, induces apoptosis and G2-M arrest via poisoning topoisomerase II.
Molecular cancer therapeutics 2007;6(2):484-95.
2007: Hua Zhang; Xiao-Ning Wang; Li-Ping Lin; Jian Ding; Jian-Min Yue
Indole alkaloids from three species of the Ervatamia genus: E. officinalis, E. divaricata, and E. divaricata Gouyahua.
Journal of natural products 2007;70(1):54-9.
2007: Hai-Hong Li; Xiu-Hua Zheng; Jin-zhi Tan; Li-Li Chen; Hong Liu; Xiao-Min Luo; Xu Shen; Li-Ping Lin; Kai-Xian Chen; Jian Ding; Hua-Liang Jiang
Design, synthesis, antitumor evaluations and molecular modeling studies of novel 3,5-substituted indolin-2-one derivatives.
Acta pharmacologica Sinica 2007;28(1):140-52.
2006: Da-Qiang Li; Yi-Feng Hou; Jiong Wu; Yi Chen; Jin-Song Lu; Gen-hong Di; Zhou-luo Ou; Zhen-zhou Shen; Jian Ding; Zhi-min Shao
Gene expression profile analysis of an isogenic tumour metastasis model reveals a functional role for oncogene AF1Q in breast cancer metastasis.
European journal of cancer (Oxford, England : 1990) 2006;42(18):3274-86.
2006: Jian Wang; Zhou-luo Ou; Yi-Feng Hou; Jian-Min Luo; Zhen-zhou Shen; Jian Ding; Zhi-min Shao
Enhanced expression of Duffy antigen receptor for chemokines by breast cancer cells attenuates growth and metastasis potential.
Oncogene 2006;25(54):7201-11.
2006: Zhi-Gang Zhuang; Gen-hong Di; Zhen-zhou Shen; Jian Ding; Zhi-min Shao
Enhanced expression of LKB1 in breast cancer cells attenuates angiogenesis, invasion, and metastatic potential.
Molecular cancer research : MCR 2006;4(11):843-9.
2006: Chao-Xin Hu; Zhi-Li Zuo; Bing Xiong; Jin-Gui Ma; Meiyu Geng; Li-Ping Lin; Hua-Liang Jiang; Jian Ding
Salvicine functions as novel topoisomerase II poison by binding to ATP pocket.
Molecular pharmacology 2006;70(5):1593-601.
2006: Sheng Yin; Cheng-Qi Fan; Xiao-Ning Wang; Li-Ping Lin; Jian Ding; Jian-Min Yue
Xylogranatins A-D: novel tetranortriterpenoids with an unusual 9,10-seco scaffold from marine mangrove Xylocarpus granatum.
Organic letters 2006;8(21):4935-8.
2006: Huajun Zhao; Haiying Liu; Yi Chen; Xianliang Xin; Jing Li; Yongtai Hou; Zhonghua Zhang; Xiongwen Zhang; Chengying Xie; Meiyu Geng; Jian Ding
Oligomannurarate sulfate, a novel heparanase inhibitor simultaneously targeting basic fibroblast growth factor, combats tumor angiogenesis and metastasis.
Cancer research 2006;66(17):8779-87.
2006: Jian Li; Jin-zhi Tan; Li-li Chen; Zhang Jian; Xu Shen; Chang-lin Mei; Li-li Fu; Li-Ping Lin; Jian Ding; Bing Xiong; Xi-shan Xiong; Hong Liu; Xiao-Min Luo; Hua-Liang Jiang
Design, synthesis and antitumor evaluation of a new series of N-substituted-thiourea derivatives.
Acta pharmacologica Sinica 2006;27(9):1259-71.
2006: Xiao-Ning Wang; Sheng Yin; Cheng-Qi Fan; Fang-Dao Wang; Li-Ping Lin; Jian Ding; Jian-Min Yue
Turrapubesins A and B, first examples of halogenated and maleimide-bearing limonoids in nature from Turraea pubescens.
Organic letters 2006;8(17):3845-8.
2006: Yan Gao; Li-Ping Lin; Cai-Hua Zhu; Yi Chen; Yong-Tai Hou; Jian Ding
Growth arrest induced by C75, A fatty acid synthase inhibitor, was partially modulated by p38 MAPK but not by p53 in human hepatocellular carcinoma.
Cancer biology & therapy 2006;5(8):978-85.
2006: Chao Zhang; Fan Yang; Xiong-Wen Zhang; Shun-Chun Wang; Mei-Hong Li; Li-Ping Lin; Jian Ding
Grateloupia longifolia polysaccharide inhibits angiogenesis by downregulating tissue factor expression in HMEC-1 endothelial cells.
British journal of pharmacology 2006;148(6):741-51.
2006: Jian Ding; Ze-Hong Miao; Ling-Hua Meng; Meiyu Geng
Emerging cancer therapeutic opportunities target DNA-repair systems.
Trends in pharmacological sciences 2006;27(6):338-44.
2006: Li-She Gan; Cheng-Qi Fan; Sheng-Ping Yang; Yan Wu; Li-Ping Lin; Jian Ding; Jian-Min Yue
Flueggenines A and B, two novel C,C-linked dimeric indolizidine alkaloids from Flueggea virosa.
Organic letters 2006;8(11):2285-8.
2006: Hua Zhang; Sheng-Ping Yang; Cheng-Qi Fan; Jian Ding; Jian-Min Yue
Daphniyunnines A-E, alkaloids from Daphniphyllum yunnanense.
Journal of natural products 2006;69(4):553-7.
2006: Yun-Guang Tong; Xiong-Wen Zhang; Meiyu Geng; Jian-Min Yue; Xian-liang Xin; Fang Tian; Xu Shen; Lin-Jiang Tong; Mei-Hong Li; Chao Zhang; Wei-Hong Li; Li-Ping Lin; Jian Ding
Pseudolarix acid B, a new tubulin-binding agent, inhibits angiogenesis by interacting with a novel binding site on tubulin.
Molecular pharmacology 2006;69(4):1226-33.
2006: Li Zhong; Xiao-Ning Guo; Xiu-Hua Zhang; Qi-Ming Sun; Lin-Jiang Tong; Zhi-Xing Wu; Xiao-Min Luo; Hua-Liang Jiang; Fa-Jun Nan; Xiong-Wen Zhang; Li-Ping Lin; Jian Ding
TKI-31 inhibits angiogenesis by combined suppression signaling pathway of VEGFR2 and PDGFRbeta.
Cancer biology & therapy 2006;5(3):323-30.
2006: Li-She Gan; Sheng-Ping Yang; Yan Wu; Jian Ding; Jian-Min Yue
Terpenoid indole alkaloids from Winchia calophylla.
Journal of natural products 2006;69(1):18-22.
2005: Li Gan; Xian-liang Xin; Jing Li; Hai Y Liu; Zhen Q Zhang; Jin Qian; Jian Ding; Meiyu Geng
Characterization of conformational epitope of alginate-derived polymannuronates by surface plasmon resonance.
Biochimie 2005;87(11):959-66.
2005: Hua-Jun Zhao; Xiong-Wen Zhang; Jian Ding
[Heparanase: target for cancer metastatic therapy].
Yao xue xue bao = Acta pharmaceutica Sinica 2005;40(10):871-5.
2005: Xin Chen; Zha-Jun Zhan; Xiong-Wen Zhang; Jian Ding; Jian-Min Yue
Sesquiterpene lactones with potent cytotoxic activities from Vernonia chinensis.
Planta medica 2005;71(10):949-54.
2005: Xiao-Ning Guo; Li Zhong; Jin-zhi Tan; Jian Li; Xiao-Min Luo; Hua-Liang Jiang; Fa-Jun Nan; Li-Ping Lin; Xiong-Wen Zhang; Jian Ding
In vitro pharmacological characterization of TKI-28, a broad-spectrum tyrosine kinase inhibitor with anti-tumor and anti-angiogenic effects.
Cancer biology & therapy 2005;4(10):1125-32.
2005: Hua-Rui Lu; Hong Zhu; Min Huang; Yi Chen; Yu-Jun Cai; Ze-Hong Miao; Jin-Sheng Zhang; Jian Ding
Reactive oxygen species elicit apoptosis by concurrently disrupting topoisomerase II and DNA-dependent protein kinase.
Molecular pharmacology 2005;68(4):983-94.
2005: Xiao-fang Yi; Sheng-tao Yuan; Li-juan Lu; Jian Ding; You-ji Feng
A clinically relevant orthotopic implantation nude mouse model of human epithelial ovarian cancer--based on consecutive observation.
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 2005;15(5):850-5.
2005: Jie Wang; Zhou-luo Ou; Yi-Feng Hou; Jian-Min Luo; Yi Chen; Jin Zhou; Zhen-zhou Shen; Jian Ding; Zhi-min Shao
[Duffy antigen receptor for chemokines attenuates breast cancer growth and metastasis: an experiment with nude mice].
Zhonghua yi xue za zhi 2005;85(29):2033-7.
2005: Fang Tian; Xiongwen Zhang; Yunguang Tong; Yanghua Yi; Shilong Zhang; Ling Li; Peng Sun; Liping Lin; Jian Ding
PE, a new sulfated saponin from sea cucumber, exhibits anti-angiogenic and anti-tumor activities in vitro and in vivo.
Cancer biology & therapy 2005;4(8):874-82.
2005: Yi Chen; Ze-Hong Miao; Wei-Min Zhao; Jian Ding
The p53 pathway is synergized by p38 MAPK signaling to mediate 11,11'-dideoxyverticillin-induced G2/M arrest.
FEBS letters 2005;579(17):3683-90.
2005: Yi-Feng Hou; Sheng-tao Yuan; He-cheng Li; Jiong Wu; Jin-Song Lu; Li-juan Lu; Gang Liu; Zhen-zhou Shen; Jian Ding; Zhi-min Shao
[In vitro study of the effects of estrogen receptor beta expression on the biological behavior of a human breast cancer cell line].
Zhonghua zhong liu za zhi [Chinese journal of oncology] 2005;27(7):389-92.
2005: Benchun Miao; Jing Li; Xueyan Fu; Jian Ding; Meiyu Geng
T-cell receptor (TCR)/CD3 is involved in sulfated polymannuroguluronate (SPMG)-induced T lymphocyte activation.
International immunopharmacology 2005;5(7-8):1171-82.
2005: Yi-Xiang Zhang; Yi Chen; Xiao-Ning Guo; Xiong-Wen Zhang; Wei-Min Zhao; Li Zhong; Jin Zhou; Yong Xi; Li-Ping Lin; Jian Ding
11,11'-dideoxy-verticillin: a natural compound possessing growth factor receptor tyrosine kinase-inhibitory effect with anti-tumor activity.
Anti-cancer drugs 2005;16(5):515-24.
2005: Yunguang Tong; Xiongwen Zhang; Fang Tian; Yanghua Yi; Qiangzhi Xu; Ling Li; Linjiang Tong; Liping Lin; Jian Ding
Philinopside A, a novel marine-derived compound possessing dual anti-angiogenic and anti-tumor effects.
International journal of cancer. Journal international du cancer 2005;114(6):843-53.
2005: Jing-Yu Lang; Hua Chen; Jin Zhou; Yi-Xiang Zhang; Xiong-Wen Zhang; Mei-Hong Li; Li-Ping Lin; Jin-Sheng Zhang; Michael P Waalkes; Jian Ding
Antimetastatic effect of salvicine on human breast cancer MDA-MB-435 orthotopic xenograft is closely related to Rho-dependent pathway.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(9):3455-64.
2005: Haiying Liu; Meiyu Geng; Xianliang Xin; Fuchuan Li; Zhenqing Zhang; Jing Li; Jian Ding
Multiple and multivalent interactions of novel anti-AIDS drug candidates, sulfated polymannuronate (SPMG)-derived oligosaccharides, with gp120 and their anti-HIV activities.
Glycobiology 2005;15(5):501-10.
2005: Yi Chen; Yi-Xiang Zhang; Mei-Hong Li; Wei-Min Zhao; Yu-Hua Shi; Ze-Hong Miao; Xiong-Wen Zhang; Li-Ping Lin; Jian Ding
Antiangiogenic activity of 11,11'-dideoxyverticillin, a natural product isolated from the fungus Shiraia bambusicola.
Biochemical and biophysical research communications 2005;329(4):1334-42.
2005: Li Zhong; Xiao-Ning Guo; Xiu-Hua Zhang; Zhi-Xing Wu; Xiao-Min Luo; Hua-Liang Jiang; Li-Ping Lin; Xiong-Wen Zhang; Jian Ding
Expression and purification of the catalytic domain of human vascular endothelial growth factor receptor 2 for inhibitor screening.
Biochimica et biophysica acta 2005;1722(3):254-61.
2005: Hua-Rui Lu; Ling-Hua Meng; Min Huang; Hong Zhu; Ze-Hong Miao; Jian Ding
DNA damage, c-myc suppression and apoptosis induced by the novel topoisomerase II inhibitor, salvicine, in human breast cancer MCF-7 cells.
Cancer chemotherapy and pharmacology 2005;55(3):286-94.
2005: Ying Fan; Jinfeng Hu; Jing Li; Zhao Yang; Xianliang Xin; Jia Wang; Jian Ding; Meiyu Geng
Effect of acidic oligosaccharide sugar chain on scopolamine-induced memory impairment in rats and its related mechanisms.
Neuroscience letters 2005;374(3):222-6.
2005: Zha-Jun Zhan; Cheng-Qi Fan; Jian Ding; Jian-Min Yue
Novel diterpenoids with potent inhibitory activity against endothelium cell HMEC and cytotoxic activities from a well-known TCM plant Daphne genkwa.
Bioorganic & medicinal chemistry 2005;13(3):645-55.
2005: Wei Xia; Jing Li; Meiyu Geng; Xianliang Xin; Jian Ding
Potentiation of T cell function by a marine algae-derived sulfated polymannuroguluronate: in vitro analysis of novel mechanisms.
Journal of pharmacological sciences 2005;97(1):107-15.
2004: Mei-Hong Li; Ze-Hong Miao; Wen-Fu Tan; Jian-Min Yue; Chao Zhang; Li-Ping Lin; Xiong-Wen Zhang; Jian Ding
Pseudolaric acid B inhibits angiogenesis and reduces hypoxia-inducible factor 1alpha by promoting proteasome-mediated degradation.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(24):8266-74.
2004: W H Tang; Sheng-tao Yuan; Bing-Sheng Wang; Li-juan Lu; Jian Ding; Z R Yuan
Establishment of a subcutaneous model of the human extrahepatic bile duct carcinoma in nude mice via transplantation of histologically intact tumor tissue.
Journal of experimental & clinical cancer research : CR 2004;23(4):661-7.
2004: Wei-Jun Liu; Yong-Wei Zhang; Ying Shen; Jian-Fei Jiang; Ze-Hong Miao; Jian Ding
Telomerase inhibition is a specific early event in salvicine-treated human lung adenocarcinoma A549 cells.
Biochemical and biophysical research communications 2004;323(2):660-7.
2004: Yi Chen; Ze-Hong Miao; Jian Ding
[The emergent role of p38 MAPKs in the regulation of cell cycle].
Sheng li ke xue jin zhan [Progress in physiology] 2004;35(4):315-20.
2004: Wei-Jun Liu; Yong-Wei Zhang; Zhi-Xiang Zhang; Jian Ding
Alternative splicing of human telomerase reverse transcriptase may not be involved in telomerase regulation during all-trans-retinoic acid-induced HL-60 cell differentiation.
Journal of pharmacological sciences 2004;96(2):106-14.
2004: Li Gan; Xianliang Xin; Meiyu Geng; Jian Ding
Immunogenic comparison of two coupling methods of marine polysaccharide to bovine serum albumin.
Biological & pharmaceutical bulletin 2004;27(10):1532-6.
2004: Wen-Fu Tan; Xiong-Wen Zhang; Mei-Hong Li; Jian-Min Yue; Yi Chen; Li-Ping Lin; Jian Ding
Pseudolarix acid B inhibits angiogenesis by antagonizing the vascular endothelial growth factor-mediated anti-apoptotic effect.
European journal of pharmacology 2004;499(3):219-28.
2004: Jun Huo; Sheng-Ping Yang; Jian Ding; Jian-Min Yue
Cytotoxic sesquiterpene lactones from Eupatorium lindleyanum.
Journal of natural products 2004;67(9):1470-5.
2004: Benchun Miao; Meiyu Geng; Jing Li; Fuchuan Li; Haixia Chen; Huashi Guan; Jian Ding
Sulfated polymannuroguluronate, a novel anti-acquired immune deficiency syndrome (AIDS) drug candidate, targeting CD4 in lymphocytes.
Biochemical pharmacology 2004;68(4):641-9.
2004: Xiao-Ning Guo; Li Zhong; Xiu-Hua Zhang; Wei-Min Zhao; Xiong-Wen Zhang; Li-Ping Lin; Jian Ding
Evaluation of active recombinant catalytic domain of human ErbB-2 tyrosine kinase, and suppression of activity by a naturally derived inhibitor, ZH-4B.
Biochimica et biophysica acta 2004;1673(3):186-93.
2004: Yi Chen; Jian Ding
[Heat shock protein 90: novel target for cancer therapy].
Ai zheng = Aizheng = Chinese journal of cancer 2004;23(8):968-74.
2004: Yi-Feng Hou; Sheng-tao Yuan; He-cheng Li; Jiong Wu; Jin-Song Lu; Gang Liu; Li-juan Lu; Zhen-zhou Shen; Jian Ding; Zhi-min Shao
ERbeta exerts multiple stimulative effects on human breast carcinoma cells.
Oncogene 2004;23(34):5799-806.
2004: Ze-Hong Miao; Lin-Jiang Tong; Jin-Sheng Zhang; Jia-xian Han; Jian Ding
Characterization of salvicine-resistant lung adenocarcinoma A549/SAL cell line.
International journal of cancer. Journal international du cancer 2004;110(5):627-32.
2004: Shengtao Yuan; Xiongwen Zhang; Lijuan Lu; Chenghui Xu; Weiyi Yang; Jian Ding
Anticancer activity of methoxymorpholinyl doxorubicin (PNU 152243) on human hepatocellular carcinoma.
Anti-cancer drugs 2004;15(6):641-6.
2004: Yunguang Tong; Xiongwen Zhang; Weimin Zhao; Yixiang Zhang; Jingyu Lang; Yuhua Shi; Wenfu Tan; Meihong Li; Yongwei Zhang; Linjiang Tong; He Lu; Liping Lin; Jian Ding
Anti-angiogenic effects of Shiraiachrome A, a compound isolated from a Chinese folk medicine used to treat rheumatoid arthritis.
European journal of pharmacology 2004;494(2-3):101-9.
2004: Xiao-Chun Huang; Di Zhao; Yue-Wei Guo; Hou-Ming Wu; Li-Ping Lin; Zhong-Hua Wang; Jian Ding; Yong-Shui Lin
Lingshuiol, a novel polyhydroxyl compound with strongly cytotoxic activity from the marine dinoflagellate Amphidinium sp.
Bioorganic & medicinal chemistry letters 2004;14(12):3117-20.
2004: Jinfeng Hu; Meiyu Geng; Jing Li; Xianliang Xin; Jia Wang; Minke Tang; Juntian Zhang; Xiao Zhang; Jian Ding
Acidic oligosaccharide sugar chain, a marine-derived acidic oligosaccharide, inhibits the cytotoxicity and aggregation of amyloid beta protein.
Journal of pharmacological sciences 2004;95(2):248-55.
2003: Ze-Hong Miao; Tao Tang; Yi-Xiang Zhang; Jin-Sheng Zhang; Jian Ding
Cytotoxicity, apoptosis induction and downregulation of MDR-1 expression by the anti-topoisomerase II agent, salvicine, in multidrug-resistant tumor cells.
International journal of cancer. Journal international du cancer 2003;106(1):108-15.
2003: Lichun Wang; Meiyu Geng; Jing Li; Huashi Guan; Jian Ding
Studies of marine sulfated polymannuroguluronate on endothelial cell proliferation and endothelial immunity and related mechanisms.
Journal of pharmacological sciences 2003;92(4):367-73.
2003: Ze-Hong Miao; Jian Ding
[Research advances on circumventing tumor multidrug resistance].
Ai zheng = Aizheng = Chinese journal of cancer 2003;22(8):886-92.
2003: Ze-Hong Miao; Jian Ding
Transcription factor c-Jun activation represses mdr-1 gene expression.
Cancer research 2003;63(15):4527-32.
2003: Chen Qing; Ze-Hong Miao; Lin-Jiang Tong; Jin-Sheng Zhang; Jian Ding
Actinomycin D inhibiting K562 cell apoptosis elicited by salvicine but not decreasing its cytotoxicity.
Acta pharmacologica Sinica 2003;24(5):415-21.
2003: Ying Li; Jin Ming Wu; Feng Shan; Guang Shao Wu; Jian Ding; Dong Xiao; Jia-xian Han; Ghanem Atassi; stephane leonce; Daniel-Henri Caignard; Pierre Renard
Synthesis and cytotoxicity of dihydroartemisinin ethers containing cyanoarylmethyl group.
Bioorganic & medicinal chemistry 2003;11(6):977-84.
2003: Wei-Jun Liu; Ying Shen; Jian Ding
[Protein phosphatase 2A: its structure, function and activity regulation].
Sheng wu hua xue yu sheng wu wu li xue bao Acta biochimica et biophysica Sinica 2003;35(2):105-12.
2003: Wen-Fu Tan; Li-Ping Lin; Mei-hong Li; Yi-Xiang Zhang; Yun-guang Tong; Dong Xiao; Jian Ding
Quercetin, a dietary-derived flavonoid, possesses antiangiogenic potential.
European journal of pharmacology 2003;459(2-3):255-62.
2002: Wei-Jun Liu; Jian-Fei Jiang; Dong Xiao; Jian Ding
Down-regulation of telomerase activity via protein phosphatase 2A activation in salvicine-induced human leukemia HL-60 cell apoptosis.
Biochemical pharmacology 2002;64(12):1677-87.
2002: Ling-ji Chen; Jia-xian Han; Wei-yi Yang; Li-juan Lu; Jia-liu Zhang; Qiu-long Yang; Sheng-tao Yuan; Jian Ding
[Inhibition of mixture of lucid garoderma and lucid garoderma spore on tumor cell in vitro and in vivo].
Ai zheng = Aizheng = Chinese journal of cancer 2002;21(12):1341-4.
2002: Jian Ding; Yongsu Zhen; Yunguang Tong; Jianmin Yue; Dong Xiao
Novel anti-angiogenetic agents developing in China.
Gan to kagaku ryoho. Cancer & chemotherapy 2002;29 Suppl 1():59-66.
2001: Ling-Hua Meng; Jin-Sheng Zhang; Jian Ding
Salvicine, a novel DNA topoisomerase II inhibitor, exerting its effects by trapping enzyme-DNA cleavage complexes.
Biochemical pharmacology 2001;62(6):733-41.
2001: X Ma; Biao Yu; Yongzheng Hui; Z Miao; Jian Ding
Synthesis of steroidal glycosides bearing the disaccharide moiety of OSW-1 and their antitumor activities.
Carbohydrate research 2001;334(2):159-64.
2001: X Ma; Biao Yu; Yongzheng Hui; Z Miao; Jian Ding
Synthesis of OSW-1 analogues and a dimer and their antitumor activities.
Bioorganic & medicinal chemistry letters 2001;11(16):2153-6.
2001: Ling-Hua Meng; X X He; Jin-Sheng Zhang; Jian Ding
DNA topoisomerase II as the primary cellular target for salvicine in Saccharomyces cerevisiae.
Acta pharmacologica Sinica 2001;22(8):741-6.
2001: L Meng; Jian Ding
Induction of bulk and c-myc P2 promoter-specific DNA damage by an anti-topoisomerase II agent salvicine is an early event leading to apoptosis in HL-60 cells.
FEBS letters 2001;501(1):59-64.
2001: W J Liu; Jian Ding
[Molecular mechanisms involved in the regulation of telomerase activity].
Sheng li ke xue jin zhan [Progress in physiology] 2001;32(3):220-4.
2001: YP Li; Yuan-Ying Pei; Jian Ding; Z M Shen; XY Zhang; ZH Gu; JJ Zhou
PEGylated recombinant human tumor necrosis factor alpha: preparation and anti-tumor potency.
Acta pharmacologica Sinica 2001;22(6):549-55.
2001: YP Li; Yuan-Ying Pei; ZH Zhou; XY Zhang; ZH Gu; Jian Ding; XJ Gao; Jian-Hua Zhu
PEGylated recombinant human tumor necrosis factor alpha: pharmacokinetics and anti-tumor effects.
Biological & pharmaceutical bulletin 2001;24(6):666-70.
2001: YP Li; Yuan-Ying Pei; ZH Zhou; XY Zhang; ZH Gu; Jian Ding; JJ Zhou; XJ Gao; Jian-Hua Zhu
Stealth polycyanoacrylate nanoparticles as tumor necrosis factor-alpha carriers: pharmacokinetics and anti-tumor effects.
Biological & pharmaceutical bulletin 2001;24(6):662-5.
2001: Jin Ming Wu; Feng Shan; Guang Shao Wu; Ying Li; Jian Ding; Dong Xiao; Jia-xian Han; Ghanem Atassi; stephane leonce; Daniel-Henri Caignard; Pierre Renard
Synthesis and cytotoxicity of artemisinin derivatives containing cyanoarylmethyl group.
European journal of medicinal chemistry 2001;36(5):469-79.
2001: YP Li; Yuan-Ying Pei; ZH Zhou; XY Zhang; ZH Gu; Jian Ding; JJ Zhou; XJ Gao
PEGylated polycyanoacrylate nanoparticles as tumor necrosis factor-alpha carriers.
Journal of controlled release : official journal of the Controlled Release Society 2001;71(3):287-96.
2001: Ying Li; Feng Shan; Jin Ming Wu; Guang Shao Wu; Jian Ding; Dong Xiao; W Y Yang; Ghanem Atassi; Stéphane Léonce; Daniel-Henri Caignard; Pierre Renard
Novel antitumor artemisinin derivatives targeting G1 phase of the cell cycle.
Bioorganic & medicinal chemistry letters 2001;11(1):5-8.
2000: X Ma; Biao Yu; Yongzheng Hui; D Xiao; Jian Ding
Synthesis of glycosides bearing the disaccharide of OSW-1 or its 1-->4-linked analogue and their antitumor activities.
Carbohydrate research 2000;329(3):495-505.
2000: J F Jiang; W J Liu; Jian Ding
Regulation of telomerase activity in camptothecin-induced apoptosis of human leukemia HL-60 cells.
Acta pharmacologica Sinica 2000;21(8):759-64.
1999: Q Xu; Jian Ding; H Hu; G Xu
Preparation and epitope characterization of monoclonal antibodies against firefly luciferase.
Science in China. Series C, Life sciences / Chinese Academy of Sciences 1999;42(6):577-82.
1999: JS Zhang; Jian Ding; Q M Tang; M Li; M Zhao; Li-juan Lu; L J Chen; Sheng-tao Yuan
Synthesis and antitumour activity of novel diterpenequinone salvicine and the analogs.
Bioorganic & medicinal chemistry letters 1999;9(18):2731-6.
1999: D Xiao; Jian Ding
[Advances in the study of mechanisms of the tumor angiogenesis inhibitors].
Sheng li ke xue jin zhan [Progress in physiology] 1999;30(3):219-23.
1999: C Qing; JS Zhang; Jian Ding
In vitro cytotoxicity of salvicine, a novel diterpenoid quinone.
Zhongguo yao li xue bao = Acta pharmacologica Sinica 1999;20(4):297-302.