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Gordon Amidon

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Co-Publications
Name
19
Landowski, Christopher
16
Hilfinger, John
16
Shah, Vinod
13
Welage, Lynda
11
Sun, Duxin
11
Vig, Balvinder
11
Song, Xueqin
11
Dressman, Jennifer
9
Shin, Ho-Chul
9
Oh, Doo-Man
8
Polli, James
8
Roessler, Blake
8
Sinko, Patrick
8
Barnett, Jeffrey
8
Midha, Kamal

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Publications

TOP 3
Shin Ho-Chul; Kim Hye-Ryoung; Cho Hee-Jung; Yi Hee; Cho Soo-Min; Lee Dong-Goo; El-Aty A M Abd; Kim Jin-Suk; Sun Duxin; Amidon Gordon L
Comparative gene expression of intestinal metabolizing enzymes.
Dahan Arik; Sabit Hairat; Amidon Gordon L
Multiple efflux pumps are involved in the transepithelial transport of colchicine: combined effect of p-glycoprotein and multidrug resistance-associated protein 2 leads to decreased intestinal absorption throughout the entire small intestine.
Gupta Deepak; Gupta Sheeba Varghese; Lee Kyung-Dall; Amidon Gordon L
Chemical and enzymatic stability of amino acid prodrugs containing methoxy, ethoxy and propylene glycol linkers.

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All Publications

2009: Shin Ho-Chul; Kim Hye-Ryoung; Cho Hee-Jung; Yi Hee; Cho Soo-Min; Lee Dong-Goo; El-Aty A M Abd; Kim Jin-Suk; Sun Duxin; Amidon Gordon L
Comparative gene expression of intestinal metabolizing enzymes.
Biopharmaceutics & drug disposition 2009;30(8):411-21.
2009: Dahan Arik; Sabit Hairat; Amidon Gordon L
Multiple efflux pumps are involved in the transepithelial transport of colchicine: combined effect of p-glycoprotein and multidrug resistance-associated protein 2 leads to decreased intestinal absorption throughout the entire small intestine.
Drug metabolism and disposition: the biological fate of chemicals 2009;37(10):2028-36.
2009: Gupta Deepak; Gupta Sheeba Varghese; Lee Kyung-Dall; Amidon Gordon L
Chemical and enzymatic stability of amino acid prodrugs containing methoxy, ethoxy and propylene glycol linkers.
Molecular pharmaceutics 2009;6(5):1604-11.
2009: Foster David R; Gonzales Jeffrey P; Amidon Gordon L; Welage Lynda S
Intestinal dipeptide absorption is preserved during thermal injury and cytokine treatment.
JPEN. Journal of parenteral and enteral nutrition 2009;33(5):520-8.
2009: Dahan Arik; Amidon Gordon L
Small intestinal efflux mediated by MRP2 and BCRP shifts sulfasalazine intestinal permeability from high to low, enabling its colonic targeting.
American journal of physiology. Gastrointestinal and liver physiology 2009;297(2):G371-7.
2009: Miller Jonathan M; Dahan Arik; Gupta Deepak; Varghese Sheeba; Amidon Gordon L
Quasi-equilibrium analysis of the ion-pair mediated membrane transport of low-permeability drugs.
Journal of controlled release : official journal of the Controlled Release Society 2009;137(1):31-7.
2009: Dahan Arik; Sabit Hairat; Amidon Gordon L
The H2 receptor antagonist nizatidine is a P-glycoprotein substrate: characterization of its intestinal epithelial cell efflux transport.
The AAPS journal 2009;11(2):205-13.
2009: Dahan Arik; Amidon Gordon L
Grapefruit juice and its constituents augment colchicine intestinal absorption: potential hazardous interaction and the role of p-glycoprotein.
Pharmaceutical research 2009;26(4):883-92.
2009: Chuasuwan B; Binjesoh V; Polli J E; Zhang H; Amidon G L; Junginger H E; Midha K K; Shah V P; Stavchansky S; Dressman J B; Barends D M
Biowaiver monographs for immediate release solid oral dosage forms: diclofenac sodium and diclofenac potassium.
Journal of pharmaceutical sciences 2009;98(4):1206-19.
2009: Foster David R; Yee Shiyin; Bleske Barry E; Carver Peggy L; Shea Michael J; Menon Sujatha S; Ramachandran Chandrasekharan; Welage Lynda S; Amidon Gordon L
Lack of interaction between the peptidomimetic substrates captopril and cephradine.
Journal of clinical pharmacology 2009;49(3):360-7.
2009: Foster David R; Landowski Christopher P; Zheng Xiaomei; Amidon Gordon L; Welage Lynda S
Interferon-gamma increases expression of the di/tri-peptide transporter, h-PEPT1, and dipeptide transport in cultured human intestinal monolayers.
Pharmacological research : the official journal of the Italian Pharmacological Society 2009;59(3):215-20.
2009: Dahan Arik; West Brady T; Amidon Gordon L
Segmental-dependent membrane permeability along the intestine following oral drug administration: Evaluation of a triple single-pass intestinal perfusion (TSPIP) approach in the rat.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2009;36(2-3):320-9.
2009: Dahan Arik; Amidon Gordon L
Segmental dependent transport of low permeability compounds along the small intestine due to P-glycoprotein: the role of efflux transport in the oral absorption of BCS class III drugs.
Molecular pharmaceutics 2009;6(1):19-28.
2009: Sheng Jennifer J; McNamara Daniel P; Amidon Gordon L
Toward an in vivo dissolution methodology: a comparison of phosphate and bicarbonate buffers.
Molecular pharmaceutics 2009;6(1):29-39.
2008: Arnal J; Gonzalez-Alvarez I; Bermejo M; Amidon G L; Junginger H E; Kopp S; Midha K K; Shah V P; Stavchansky S; Dressman J B; Barends D M
Biowaiver monographs for immediate release solid oral dosage forms: aciclovir.
Journal of pharmaceutical sciences 2008;97(12):5061-73.
2008: Sheng Jennifer J; Sirois Paul J; Dressman Jennifer B; Amidon Gordon L
Particle diffusional layer thickness in a USP dissolution apparatus II: a combined function of particle size and paddle speed.
Journal of pharmaceutical sciences 2008;97(11):4815-29.
2008: Tsume Yasuhiro; Hilfinger John M; Amidon Gordon L
Enhanced cancer cell growth inhibition by dipeptide prodrugs of floxuridine: increased transporter affinity and metabolic stability.
Molecular pharmaceutics 2008;5(5):717-27.
2008: Higaki Kazutaka; Choe Sally Y; Löbenberg Raimar; Welage Lynda S; Amidon Gordon L
Mechanistic understanding of time-dependent oral absorption based on gastric motor activity in humans.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2008;70(1):313-25.
2008: Becker C; Dressman J B; Amidon G L; Junginger H E; Kopp S; Midha K K; Shah V P; Stavchansky S; Barends D M
Biowaiver monographs for immediate release solid oral dosage forms: pyrazinamide.
Journal of pharmaceutical sciences 2008;97(9):3709-20.
2008: Tubic-Grozdanis Marija; Hilfinger John M; Amidon Gordon L; Kim Jae Seung; Kijek Paul; Staubach Petra; Langguth Peter
Pharmacokinetics of the CYP 3A substrate simvastatin following administration of delayed versus immediate release oral dosage forms.
Pharmaceutical research 2008;25(7):1591-600.
2008: Polli James E; Abrahamsson Bertil S I; Yu Lawrence X; Amidon Gordon L; Baldoni John M; Cook Jack A; Fackler Paul; Hartauer Kerry; Johnston Gordon; Krill Steve L; Lipper Robert A; Malick Waseem A; Shah Vinod P; Sun Duxin; Winkle Helen N; Wu Yunhui; Zhang Hua
Summary workshop report: bioequivalence, biopharmaceutics classification system, and beyond.
The AAPS journal 2008;10(2):373-9.
2008: Lai Longsheng; Xu Zhaohui; Zhou Jiahai; Lee Kyung-Dall; Amidon Gordon L
Molecular basis of prodrug activation by human valacyclovirase, an alpha-amino acid ester hydrolase.
The Journal of biological chemistry 2008;283(14):9318-27.
2008: Becker C; Dressman J B; Amidon G L; Junginger H E; Kopp S; Midha K K; Shah V P; Stavchansky S; Barends D M
Biowaiver monographs for immediate release solid oral dosage forms: ethambutol dihydrochloride.
Journal of pharmaceutical sciences 2008;97(4):1350-60.
2008: Benet Leslie Z; Amidon Gordon L; Barends Dirk M; Lennernäs Hans; Polli James E; Shah Vinod P; Stavchansky Salomon A; Yu Lawrence X
The use of BDDCS in classifying the permeability of marketed drugs.
Pharmaceutical research 2008;25(3):483-8.
2008: Granero Gladys E; Amidon Gordon L
Possibility of enterohepatic recycling of ketoprofen in dogs.
International journal of pharmaceutics 2008;349(1-2):166-71.
2008: Tsume Yasuhiro; Vig Balvinder S; Sun Jing; Landowski Christopher P; Hilfinger John M; Ramachandran Chandrasekharan; Amidon Gordon L
Enhanced absorption and growth inhibition with amino acid monoester prodrugs of floxuridine by targeting hPEPT1 transporters.
Molecules (Basel, Switzerland) 2008;13(7):1441-54.
2007: Mittal Sachin; Tsume Yasuhiro; Landowski Christopher P; Lee Kyung-Dall; Hilfinger John M; Amidon Gordon L
Proline prodrug of melphalan, prophalan-L, demonstrates high therapeutic index in a murine melanoma model.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2007;67(3):752-8.
2007: Kim Hye-Ryoung; Park Sung-Won; Cho Hee-Jung; Chae Kyung-Ae; Sung Ji-Min; Kim Jin-Suk; Landowski Christopher P; Sun Duxin; Abd El-Aty A M; Amidon Gordon L; Shin Ho-Chul
Comparative gene expression profiles of intestinal transporters in mice, rats and humans.
Pharmacological research : the official journal of the Italian Pharmacological Society 2007;56(3):224-36.
2007: Mittal Sachin; Song Xueqin; Vig Balvinder S; Amidon Gordon L
Proline prodrug of melphalan targeted to prolidase, a prodrug activating enzyme overexpressed in melanoma.
Pharmaceutical research 2007;24(7):1290-8.
2007: Becker C; Dressman J B; Amidon G L; Junginger H E; Kopp S; Midha K K; Shah V P; Stavchansky S; Barends D M;
Biowaiver monographs for immediate release solid oral dosage forms: isoniazid.
Journal of pharmaceutical sciences 2007;96(3):522-31.
2007: Fujii Yoshimine; Takahashi Masayuki; Morita Hiromi; Kikuchi Hiroshi; Aramaki Yukihiko; Amidon Gordon L
Characteristics of gastrointestinal absorption of DX-9065a, a new synthetic anticoagulant.
Drug metabolism and pharmacokinetics 2007;22(1):26-32.
2006: Kim Jae-Seung; Mitchell Stefanie; Kijek Paul; Tsume Yasuhiro; Hilfinger John; Amidon Gordon L
The suitability of an in situ perfusion model for permeability determinations: utility for BCS class I biowaiver requests.
Molecular pharmaceutics 2006;3(6):686-94.
2006: Takagi Toshihide; Ramachandran Chandrasekharan; Bermejo Marival; Yamashita Shinji; Yu Lawrence X; Amidon Gordon L
A provisional biopharmaceutical classification of the top 200 oral drug products in the United States, Great Britain, Spain, and Japan.
Molecular pharmaceutics 2006;3(6):631-43.
2006: Sheng Jennifer J; Kasim Nehal A; Chandrasekharan Ramachandran; Amidon Gordon L
Solubilization and dissolution of insoluble weak acid, ketoprofen: effects of pH combined with surfactant.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2006;29(3-4):306-14.
2006: Granero G E; Ramachandran C; Amidon G L
Rapid in vivo dissolution of ketoprofen: implications on the biopharmaceutics classification system.
Die Pharmazie 2006;61(8):673-6.
2006: Cao Xianhua; Gibbs Seth T; Fang Lanyan; Miller Heather A; Landowski Christopher P; Shin Ho-Chul; Lennernas Hans; Zhong Yanqiang; Amidon Gordon L; Yu Lawrence X; Sun Duxin
Why is it challenging to predict intestinal drug absorption and oral bioavailability in human using rat model.
Pharmaceutical research 2006;23(8):1675-86.
2006: Granero Gladys E; Amidon Gordon L
Stability of valacyclovir: implications for its oral bioavailability.
International journal of pharmaceutics 2006;317(1):14-8.
2006: Lorenzi Philip L; Landowski Christopher P; Brancale Andrea; Song Xueqin; Townsend Leroy B; Drach John C; Amidon Gordon L
N-methylpurine DNA glycosylase and 8-oxoguanine dna glycosylase metabolize the antiviral nucleoside 2-bromo-5,6-dichloro-1-(beta-D-ribofuranosyl)benzimidazole.
Drug metabolism and disposition: the biological fate of chemicals 2006;34(6):1070-7.
2006: Manzo R H; Olivera M E; Amidon G L; Shah V P; Dressman J B; Barends D M
Biowaiver monographs for immediate release solid oral dosage forms: amitriptyline hydrochloride.
Journal of pharmaceutical sciences 2006;95(5):966-73.
2006: Jantratid E; Prakongpan S; Dressman J B; Amidon G L; Junginger H E; Midha K K; Barends D M
Biowaiver monographs for immediate release solid oral dosage forms: cimetidine.
Journal of pharmaceutical sciences 2006;95(5):974-84.
2006: Shin Ho-Chul; Kim Jin-Suk; Vig Balvinder Singh; Song Xueqin; Drach John Charles; Amidon Gordon Lewis
Interaction of intestinal nucleoside transporter hCNT2 with amino acid ester prodrugs of floxuridine and 2-bromo-5,6-dichloro-1-beta-D-ribofuranosylbenzimidazole.
Biological & pharmaceutical bulletin 2006;29(2):247-52.
2006: Landowski Christopher P; Lorenzi Philip L; Song Xueqin; Amidon Gordon L
Nucleoside ester prodrug substrate specificity of liver carboxylesterase.
The Journal of pharmacology and experimental therapeutics 2006;316(2):572-80.
2006: Kalantzi L; Reppas C; Dressman J B; Amidon G L; Junginger H E; Midha K K; Shah V P; Stavchansky S A; Barends Dirk M
Biowaiver monographs for immediate release solid oral dosage forms: acetaminophen (paracetamol).
Journal of pharmaceutical sciences 2006;95(1):4-14.
2006: Jantratid Ekarat; Prakongpan Sompol; Amidon Gordon L; Dressman Jennifer B
Feasibility of biowaiver extension to biopharmaceutics classification system class III drug products: cimetidine.
Clinical pharmacokinetics 2006;45(4):385-99.
2005: Granero Gladys E; Ramachandran Chandrasekharan; Amidon Gordon L
Dissolution and solubility behavior of fenofibrate in sodium lauryl sulfate solutions.
Drug development and industrial pharmacy 2005;31(9):917-22.
2005: Landowski Christopher P; Song Xueqin; Lorenzi Philip L; Hilfinger John M; Amidon Gordon L
Floxuridine amino acid ester prodrugs: enhancing Caco-2 permeability and resistance to glycosidic bond metabolism.
Pharmaceutical research 2005;22(9):1510-8.
2005: Lorenzi Philip L; Landowski Christopher P; Song Xueqin; Borysko Katherine Z; Breitenbach Julie M; Kim Jae Seung; Hilfinger John M; Townsend Leroy B; Drach John C; Amidon Gordon L
Amino acid ester prodrugs of 2-bromo-5,6-dichloro-1-(beta-D-ribofuranosyl)benzimidazole enhance metabolic stability in vitro and in vivo.
The Journal of pharmacology and experimental therapeutics 2005;314(2):883-90.
2005: Cao Xianhua; Yu Lawrence X; Barbaciru Catalin; Landowski Christopher P; Shin Ho-Chul; Gibbs Seth; Miller Heather A; Amidon Gordon L; Sun Duxin
Permeability dominates in vivo intestinal absorption of P-gp substrate with high solubility and high permeability.
Molecular pharmaceutics 2005;2(4):329-40.
2005: Löbenberg Raimar; Kim Jae Seung; Amidon Gordon L
Pharmacokinetics of an immediate release, a controlled release and a two pulse dosage form in dogs.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2005;60(1):17-23.
2005: Landowski Christopher P; Vig Balvinder S; Song Xueqin; Amidon Gordon L
Targeted delivery to PEPT1-overexpressing cells: acidic, basic, and secondary floxuridine amino acid ester prodrugs.
Molecular cancer therapeutics 2005;4(4):659-67.
2005: Song Xueqin; Lorenzi Philip L; Landowski Christopher P; Vig Balvinder S; Hilfinger John M; Amidon Gordon L
Amino acid ester prodrugs of the anticancer agent gemcitabine: synthesis, bioconversion, metabolic bioevasion, and hPEPT1-mediated transport.
Molecular pharmaceutics 2005;2(2):157-67.
2005: Amidon Gordon L
Collaborative research training.
Molecular pharmaceutics 2005;2(2):97.
2005: Song Xueqin; Vig Balvinder S; Lorenzi Philip L; Drach John C; Townsend Leroy B; Amidon Gordon L
Amino acid ester prodrugs of the antiviral agent 2-bromo-5,6-dichloro-1-(beta-D-ribofuranosyl)benzimidazole as potential substrates of hPEPT1 transporter.
Journal of medicinal chemistry 2005;48(4):1274-7.
2005: Mittal Sachin; Song Xueqin; Vig Balvinder S; Landowski Christopher P; Kim Insook; Hilfinger John M; Amidon Gordon L
Prolidase, a potential enzyme target for melanoma: design of proline-containing dipeptide-like prodrugs.
Molecular pharmaceutics 2005;2(1):37-46.
2004: Kim Insook; Crippen Gordon M; Amidon Gordon L
Structure and specificity of a human valacyclovir activating enzyme: a homology model of BPHL.
Molecular pharmaceutics 2004;1(6):434-46.
2004: Amidon Gordon L
Molecular pharmaceutics: the NIH Roadmap and the FDA pipeline problem.
Molecular pharmaceutics 2004;1(5):337.
2004: Hosoya Ken-ichi; Tomi Masatoshi; Takayama Megumi; Komokata Yuko; Nakai Daisuke; Tokui Taro; Nishimura Kenji; Ueda Masatsugu; Obinata Masuo; Hori Satoko; Ohtsuki Sumio; Amidon Gordon L; Terasaki Tetsuya
Transporter mRNA expression in a conditionally immortalized rat small intestine epithelial cell line (TR-SIE).
Drug metabolism and pharmacokinetics 2004;19(4):264-9.
2004: Balakrishnan Anand; Rege Bhagwant D; Amidon Gordon L; Polli James E
Surfactant-mediated dissolution: contributions of solubility enhancement and relatively low micelle diffusivity.
Journal of pharmaceutical sciences 2004;93(8):2064-75.
2004: Vogelpoel H; Welink J; Amidon G L; Junginger H E; Midha K K; Möller H; Olling M; Shah V P; Barends D M
Biowaiver monographs for immediate release solid oral dosage forms based on biopharmaceutics classification system (BCS) literature data: verapamil hydrochloride, propranolol hydrochloride, and atenolol.
Journal of pharmaceutical sciences 2004;93(8):1945-56.
2004: Tamura Shigeki; Ohike Atsuo; Tokunaga Yuji; Ibuki Rinta; Amidon Gordon L; Sezaki Hitoshi; Yamashita Shinji
Effect of experimental acute renal and hepatic failure on absorption of tacrolimus in rat small intestine.
Drug metabolism and pharmacokinetics 2004;19(3):190-7.
2004: Polli James E; Yu Lawrence X; Cook Jack A; Amidon Gordon L; Borchardt Ronald T; Burnside Beth A; Burton Philip S; Chen Mei-Ling; Conner Dale P; Faustino Patrick J; Hawi Amale A; Hussain Ajaz S; Joshi Hemant N; Kwei Gloria; Lee Vincent H L; Lesko Lawrence J; Lipper Robert A; Loper Alice E; Nerurkar Shriniwas G; Polli Joseph W; Sanvordeker Dilip R; Taneja Rajneesh; Uppoor Ramana S; Vattikonda Chandra S; Wilding Ian; Zhang Guohua
Summary workshop report: biopharmaceutics classification system--implementation challenges and extension opportunities.
Journal of pharmaceutical sciences 2004;93(6):1375-81.
2004: Delaney Bryan; Stevens Luke A; Schmelzer Wade; Haworth James; McCurry Steve; Hilfinger John M; Kim Jae Seung; Tsume Yasuhiro; Amidon Gordon L; Kritchevsky David
Oral absorption of phytosterols and emulsified phytosterols by Sprague-Dawley rats.
The Journal of nutritional biochemistry 2004;15(5):289-95.
2004: Ettmayer Peter; Amidon Gordon L; Clement Bernd; Testa Bernard
Lessons learned from marketed and investigational prodrugs.
Journal of medicinal chemistry 2004;47(10):2393-404.
2004: Kim Insook; Song Xueqin; Vig Balvinder S; Mittal Sachin; Shin Ho-Chul; Lorenzi Philip J; Amidon Gordon L
A novel nucleoside prodrug-activating enzyme: substrate specificity of biphenyl hydrolase-like protein.
Molecular pharmaceutics 2004;1(2):117-27.
2004: Yu Lawrence X; Carlin Alan S; Amidon Gordon L; Hussain Ajaz S
Feasibility studies of utilizing disk intrinsic dissolution rate to classify drugs.
International journal of pharmaceutics 2004;270(1-2):221-7.
2004: Kasim Nehal A; Whitehouse Marc; Ramachandran Chandrasekharan; Bermejo Marival; Lennernäs Hans; Hussain Ajaz S; Junginger Hans E; Stavchansky Salomon A; Midha Kamal K; Shah Vinod P; Amidon Gordon L
Molecular properties of WHO essential drugs and provisional biopharmaceutical classification.
Molecular pharmaceutics 2004;1(1):85-96.
2004: Faria Teresa N; Timoszyk Julita K; Stouch Terry R; Vig Balvinder S; Landowski Christopher P; Amidon Gordon L; Weaver C David; Wall Doris A; Smith Ronald L
A novel high-throughput pepT1 transporter assay differentiates between substrates and antagonists.
Molecular pharmaceutics 2004;1(1):67-76.
2004: Amidon Gordon L
Finding the "Magic".
Molecular pharmaceutics 2004;1(1):1.
2004: Sun Duxin; Yu Lawrence X; Hussain Munir A; Wall Doris A; Smith Ronald L; Amidon Gordon L
In vitro testing of drug absorption for drug 'developability' assessment: forming an interface between in vitro preclinical data and clinical outcome.
Current opinion in drug discovery & development 2004;7(1):75-85.
2004: Landowski Christopher P; Anderle Pascale; Sun Duxin; Sadee Wolfgang; Amidon Gordon L
Transporter and ion channel gene expression after Caco-2 cell differentiation using 2 different microarray technologies.
The AAPS journal 2004;6(3):e21.
2003: Landowski Christopher P; Han Hyo-kyung; Lee Kyung-Dall; Amidon Gordon L
A fluorescent hPept1 transporter substrate for uptake screening.
Pharmaceutical research 2003;20(11):1738-45.
2003: Vig Balvinder S; Lorenzi Philip J; Mittal Sachin; Landowski Christopher P; Shin Ho-Chul; Mosberg Henry I; Hilfinger John M; Amidon Gordon L
Amino acid ester prodrugs of floxuridine: synthesis and effects of structure, stereochemistry, and site of esterification on the rate of hydrolysis.
Pharmaceutical research 2003;20(9):1381-8.
2003: Shin Ho-Chul; Kim Jong-Choon; Chung Moon-Koo; Jung Yong-Ho; Kim Jin-Suk; Lee Mi-Kyung; Amidon Gordon L
Fetal and maternal tissue distribution of the new fluoroquinolone DW-116 in pregnant rats.
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 2003;136(1):95-102.
2003: Panyam Jayanth; Dali Manisha M; Sahoo Sanjeeb K; Ma Wenxue; Chakravarthi Sudhir S; Amidon Gordon L; Levy Robert J; Labhasetwar Vinod
Polymer degradation and in vitro release of a model protein from poly(D,L-lactide-co-glycolide) nano- and microparticles.
Journal of controlled release : official journal of the Controlled Release Society 2003;92(1-2):173-87.
2003: Shin Ho-Chul; Landowski Christopher P; Sun Duxin; Vig Balvinder S; Kim Insook; Mittal Sachin; Lane Majella; Rosania Gustavo; Drach John C; Amidon Gordon L
Functional expression and characterization of a sodium-dependent nucleoside transporter hCNT2 cloned from human duodenum.
Biochemical and biophysical research communications 2003;307(3):696-703.
2003: Landowski Christopher P; Sun Duxin; Foster David R; Menon Sujatha S; Barnett Jeffrey L; Welage Lynda S; Ramachandran Chandrasekharan; Amidon Gordon L
Gene expression in the human intestine and correlation with oral valacyclovir pharmacokinetic parameters.
The Journal of pharmacology and experimental therapeutics 2003;306(2):778-86.
2003: Kim Insook; Chu Xiao-Yan; Kim Seonyoung; Provoda Chester J; Lee Kyung-Dall; Amidon Gordon L
Identification of a human valacyclovirase: biphenyl hydrolase-like protein as valacyclovir hydrolase.
The Journal of biological chemistry 2003;278(28):25348-56.
2003: Tamura Shigeki; Tokunaga Yuji; Ibuki Rinta; Amidon Gordon L; Sezaki Hitoshi; Yamashita Shinji
The site-specific transport and metabolism of tacrolimus in rat small intestine.
The Journal of pharmacology and experimental therapeutics 2003;306(1):310-6.
2003: Chiu Yu-Yuan; Higaki Kazutaka; Neudeck Brien L; Barnett Jeffrey L; Welage Lynda S; Amidon Gordon L
Human jejunal permeability of cyclosporin A: influence of surfactants on P-glycoprotein efflux in Caco-2 cells.
Pharmaceutical research 2003;20(5):749-56.
2003: Saito G; Amidon G L; Lee K-D
Enhanced cytosolic delivery of plasmid DNA by a sulfhydryl-activatable listeriolysin O/protamine conjugate utilizing cellular reducing potential.
Gene therapy 2003;10(1):72-83.
2002: Oh Doo-Man; Han Hyo-Kyung; Williamson Rufus M; Bigge Christopher F; Amidon Gordon L; Stewart Barbra H; Surendran Narayanan
Improved intestinal transport of PD 158473, an N-methyl-D-aspartate (NMDA) antagonist, by involvement of multiple transporters.
Journal of pharmaceutical sciences 2002;91(12):2579-87.
2002: Su Sheng-Fang; Amidon Gordon L; Lee Hye J
Possible degradative process of cholecystokinin analogs in rabbit jejunum brush-border membrane vesicles.
Life sciences 2002;72(1):35-47.
2002: Sun Duxin; Lennernas Hans; Welage Lynda S; Barnett Jeffery L; Landowski Christopher P; Foster David; Fleisher David; Lee Kyung-Dall; Amidon Gordon L
Comparison of human duodenum and Caco-2 gene expression profiles for 12,000 gene sequences tags and correlation with permeability of 26 drugs.
Pharmaceutical research 2002;19(10):1400-16.
2002: Yu Lawrence X; Amidon Gordon L; Polli James E; Zhao Hong; Mehta Mehul U; Conner Dale P; Shah Vinod P; Lesko Lawrence J; Chen Mei-Ling; Lee Vincent H L; Hussain Ajaz S
Biopharmaceutics classification system: the scientific basis for biowaiver extensions.
Pharmaceutical research 2002;19(7):921-5.
2002: Martinez Marilyn N; Amidon Gordon L
A mechanistic approach to understanding the factors affecting drug absorption: a review of fundamentals.
Journal of clinical pharmacology 2002;42(6):620-43.
2002: Lee Hye J; Amidon Gordon L
The effect of enzyme inhibitor and absorption site following [D-ala2, D-leu5]enkephalin oral administration in rats.
Biopharmaceutics & drug disposition 2002;23(4):131-41.
2002: Li Lilian Y; Amidon Gordon L; Kim Jae Seung; Heimbach Tycho; Kesisoglou Filippos; Topliss John T; Fleisher David
Intestinal metabolism promotes regional differences in apical uptake of indinavir: coupled effect of P-glycoprotein and cytochrome P450 3A on indinavir membrane permeability in rat.
The Journal of pharmacology and experimental therapeutics 2002;301(2):586-93.
2002: Su Sheng-Fang; Amidon Gordon L; Lee Hye J
Intestinal metabolism and absorption of cholecystokinin analogs in rats.
Biochemical and biophysical research communications 2002;292(3):632-8.
2002: Tamura Shigeki; Ohike Atsuo; Ibuki Rinta; Amidon Gordon L; Yamashita Shinji
Tacrolimus is a class II low-solubility high-permeability drug: the effect of P-glycoprotein efflux on regional permeability of tacrolimus in rats.
Journal of pharmaceutical sciences 2002;91(3):719-29.
2002: Takamatsu Narushi; Welage Lynda S; Hayashi Yayoi; Yamamoto Ryuzo; Barnett Jeffrey L; Shah Vinod P; Lesko Lawrence J; Ramachandran Chandrasekharan; Amidon Gordon L
Variability in cimetidine absorption and plasma double peaks following oral administration in the fasted state in humans: correlation with antral gastric motility.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2002;53(1):37-47.
2001: Choe S Y; Neudeck B L; Welage L S; Amidon G E; Barnett J L; Amidon G L
Novel method to assess gastric emptying in humans: the Pellet Gastric Emptying Test.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2001;14(4):347-53.
2001: Chu X Y; Sánchez-Castaño G P; Higaki K; Oh D M; Hsu C P; Amidon G L
Correlation between epithelial cell permeability of cephalexin and expression of intestinal oligopeptide transporter.
The Journal of pharmacology and experimental therapeutics 2001;299(2):575-82.
2001: Takamatsu N; Kim O N; Welage L S; Idkaidek N M; Hayashi Y; Barnett J; Yamamoto R; Lipka E; Lennernäs H; Hussain A; Lesko L; Amidon G L
Human jejunal permeability of two polar drugs: cimetidine and ranitidine.
Pharmaceutical research 2001;18(6):742-4.
2001: Higaki K; Yamashita S; Amidon G L
Time-dependent oral absorption models.
Journal of pharmacokinetics and pharmacodynamics 2001;28(2):109-28.
2001: Sun D; Landowski C P; Chu X; Wallsten R; Komorowski T E; Fleisher D; Amidon G L
Drug inhibition of Gly-Sar uptake and hPepT1 localization using hPepT1-GFP fusion protein.
AAPS pharmSci 2001;3(1):E2.
2000: Löbenberg R; Amidon G L
Modern bioavailability, bioequivalence and biopharmaceutics classification system. New scientific approaches to international regulatory standards.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2000;50(1):3-12.
2000: Löbenberg R; Krämer J; Shah V P; Amidon G L; Dressman J B
Dissolution testing as a prognostic tool for oral drug absorption: dissolution behavior of glibenclamide.
Pharmaceutical research 2000;17(4):439-44.
2000: Desai M P; Hilfinger J M; Amidon G L; Levy R J; Labhasetwar V
Immune response with biodegradable nanospheres and alum: studies in rabbits using staphylococcal enterotoxin B-toxoid.
Journal of microencapsulation 2000;17(2):215-25.
2000: Jinno J; Oh D m; Crison J R; Amidon G L
Dissolution of ionizable water-insoluble drugs: the combined effect of pH and surfactant.
Journal of pharmaceutical sciences 2000;89(2):268-74.
2000: Han H K; Amidon G L
Targeted prodrug design to optimize drug delivery.
AAPS pharmSci 2000;2(1):E6.
1999: Markland P; Zhang Y; Amidon G L; Yang V C
A pH- and ionic strength-responsive polypeptide hydrogel: synthesis, characterization, and preliminary protein release studies.
Journal of biomedical materials research 1999;47(4):595-602.
1999: Surendran N; Covitz K M; Han H; Sadee W; Oh D M; Amidon G L; Williamson R M; Bigge C F; Stewart B H
Evidence for overlapping substrate specificity between large neutral amino acid (LNAA) and dipeptide (hPEPT1) transporters for PD 158473, an NMDA antagonist.
Pharmaceutical research 1999;16(3):391-5.
1999: Han H K; Rhie J K; Oh D M; Saito G; Hsu C P; Stewart B H; Amidon G L
CHO/hPEPT1 cells overexpressing the human peptide transporter (hPEPT1) as an alternative in vitro model for peptidomimetic drugs.
Journal of pharmaceutical sciences 1999;88(3):347-50.
1999: Markland P; Amidon G L; Yang V C
Modified polypeptides containing gamma-benzyl glutamic acid as drug delivery platforms.
International journal of pharmaceutics 1999;178(2):183-92.
1999: Hsu C P; Walter E; Merkle H P; Rothen-Rutishauser B; Wunderli-Allenspach H; Hilfinger J M; Amidon G L
Function and immunolocalization of overexpressed human intestinal H+/peptide cotransporter in adenovirus-transduced Caco-2 cells.
AAPS pharmSci 1999;1(3):E12.
1999: Oh D M; Han H K; Amidon G L
Drug transport and targeting. Intestinal transport.
Pharmaceutical biotechnology 1999;12():59-88.
1998: Han H K; Oh D M; Amidon G L
Cellular uptake mechanism of amino acid ester prodrugs in Caco-2/hPEPT1 cells overexpressing a human peptide transporter.
Pharmaceutical research 1998;15(9):1382-6.
1998: Hsu C P; Hilfinger J M; Walter E; Merkle H P; Roessler B J; Amidon G L
Overexpression of human intestinal oligopeptide transporter in mammalian cells via adenoviral transduction.
Pharmaceutical research 1998;15(9):1376-81.
1998: Croyle M A; Roessler B J; Hsu C P; Sun R; Amidon G L
Beta cyclodextrins enhance adenoviral-mediated gene delivery to the intestine.
Pharmaceutical research 1998;15(9):1348-55.
1998: Croyle M A; Roessler B J; Davidson B L; Hilfinger J M; Amidon G L
Factors that influence stability of recombinant adenoviral preparations for human gene therapy.
Pharmaceutical development and technology 1998;3(3):373-83.
1998: Croyle M A; Anderson D J; Roessler B J; Amidon G L
Development of a highly efficient purification process for recombinant adenoviral vectors for oral gene delivery.
Pharmaceutical development and technology 1998;3(3):365-72.
1998: Han H; de Vrueh R L; Rhie J K; Covitz K M; Smith P L; Lee C P; Oh D M; Sadée W; Amidon G L
5'-Amino acid esters of antiviral nucleosides, acyclovir, and AZT are absorbed by the intestinal PEPT1 peptide transporter.
Pharmaceutical research 1998;15(8):1154-9.
1998: Croyle M A; Stone M; Amidon G L; Roessler B J
In vitro and in vivo assessment of adenovirus 41 as a vector for gene delivery to the intestine.
Gene therapy 1998;5(5):645-54.
1998: Idkaidek N M; Amidon G L; Smith D E; Najib N M; Hassan M M
Determination of the population pharmacokinetic parameters of sustained-release and enteric-coated oral formulations, and the suppository formulation of diclofenac sodium by simultaneous data fitting using NONMEM.
Biopharmaceutics & drug disposition 1998;19(3):169-74.
1998: Yu L X; Amidon G L
Saturable small intestinal drug absorption in humans: modeling and interpretation of cefatrizine data.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 1998;45(2):199-203.
1998: Croyle M A; Walter E; Janich S; Roessler B J; Amidon G L
Role of integrin expression in adenovirus-mediated gene delivery to the intestinal epithelium.
Human gene therapy 1998;9(4):561-73.
1998: Rhie J K; Hayashi Y; Welage L S; Frens J; Wald R J; Barnett J L; Amidon G E; Putcha L; Amidon G L
Drug marker absorption in relation to pellet size, gastric motility and viscous meals in humans.
Pharmaceutical research 1998;15(2):233-8.
1998: Lipka E; Spahn-Langguth H; Mutschler E; Amidon G L
In vivo non-linear intestinal permeability of celiprolol and propranolol in conscious dogs: evidence for intestinal secretion.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 1998;6(1):75-81.
1998: Dressman J B; Amidon G L; Reppas C; Shah V P
Dissolution testing as a prognostic tool for oral drug absorption: immediate release dosage forms.
Pharmaceutical research 1998;15(1):11-22.
1998: Han H K; Stewart B H; Doherty A M; Cody W L; Amidon G L
In vitro stability and intestinal absorption characteristics of hexapeptide endothelin receptor antagonists.
Life sciences 1998;63(18):1599-609.
1997: Desai M P; Labhasetwar V; Walter E; Levy R J; Amidon G L
The mechanism of uptake of biodegradable microparticles in Caco-2 cells is size dependent.
Pharmaceutical research 1997;14(11):1568-73.
1997: Walter E; Croyle M A; Roessler B J; Amidon G L
The absence of accessible vitronectin receptors in differentiated tissue hinders adenoviral-mediated gene transfer to the intestinal epithelium in vitro.
Pharmaceutical research 1997;14(9):1216-22.
1997: Takamatsu N; Welage L S; Idkaidek N M; Liu D Y; Lee P I; Hayashi Y; Rhie J K; Lennernäs H; Barnett J L; Shah V P; Lesko L; Amidon G L
Human intestinal permeability of piroxicam, propranolol, phenylalanine, and PEG 400 determined by jejunal perfusion.
Pharmaceutical research 1997;14(9):1127-32.
1997: Cheng C L; Smith D E; Carver P L; Cox S R; Watkins P B; Blake D S; Kauffman C A; Meyer K M; Amidon G L; Stetson P L
Steady-state pharmacokinetics of delavirdine in HIV-positive patients: effect on erythromycin breath test.
Clinical pharmacology and therapeutics 1997;61(5):531-43.
1997: Crison J R; Weiner N D; Amidon G L
Dissolution media for in vitro testing of water-insoluble drugs: effect of surfactant purity and electrolyte on in vitro dissolution of carbamazepine in aqueous solutions of sodium lauryl sulfate.
Journal of pharmaceutical sciences 1997;86(3):384-8.
1996: Desai M P; Labhasetwar V; Amidon G L; Levy R J
Gastrointestinal uptake of biodegradable microparticles: effect of particle size.
Pharmaceutical research 1996;13(12):1838-45.
1996: Covitz K M; Amidon G L; Sadée W
Human dipeptide transporter, hPEPT1, stably transfected into Chinese hamster ovary cells.
Pharmaceutical research 1996;13(11):1631-4.
1996: Walter E; Janich S; Roessler B J; Hilfinger J M; Amidon G L
HT29-MTX/Caco-2 cocultures as an in vitro model for the intestinal epithelium: in vitro-in vivo correlation with permeability data from rats and humans.
Journal of pharmaceutical sciences 1996;85(10):1070-6.
1996: Crison J R; Shah V P; Skelly J P; Amidon G L
Drug dissolution into micellar solutions: development of a convective diffusion model and comparison to the film equilibrium model with application to surfactant-facilitated dissolution of carbamazepine.
Journal of pharmaceutical sciences 1996;85(9):1005-11.
1996: Yu L X; Lipka E; Crison J R; Amidon G L
Transport approaches to the biopharmaceutical design of oral drug delivery systems: prediction of intestinal absorption.
Advanced drug delivery reviews 1996;19(3):359-76.
1996: Lipka E; Crison J; Amidon G L
Transmembrane transport of peptide type compounds: prospects for oral delivery.
Journal of controlled release : official journal of the Controlled Release Society 1996;39(2-3):121-9.
1995: Sadée W; Drübbisch V; Amidon G L
Biology of membrane transport proteins.
Pharmaceutical research 1995;12(12):1823-37.
1995: Polli J E; Amidon G L
Mathematical model and dimensional analysis of glycocholate binding to cholestyramine resin: implications for in vivo resin performance.
Journal of pharmaceutical sciences 1995;84(12):1446-54.
1995: Su S F; Amidon G L
Investigation into the intestinal metabolism of [D-Ala1] peptide T amide: implication for oral drug delivery.
Biochimica et biophysica acta 1995;1245(1):62-8.
1995: Lennernäs H; Crison J R; Amidon G L
Permeability and clearance views of drug absorption: a commentary.
Journal of pharmacokinetics and biopharmaceutics 1995;23(3):333-43.
1995: Lipka E; Lee I D; Langguth P; Spahn-Langguth H; Mutschler E; Amidon G L
Celiprolol double-peak occurrence and gastric motility: nonlinear mixed effects modeling of bioavailability data obtained in dogs.
Journal of pharmacokinetics and biopharmaceutics 1995;23(3):267-86.
1995: Choi H K; Flynn G L; Amidon G L
Percutaneous absorption and dermal delivery of cyclosporin A.
Journal of pharmaceutical sciences 1995;84(5):581-3.
1995: Mummaneni V; Amidon G L; Dressman J B
Gastric pH influences the appearance of double peaks in the plasma concentration-time profiles of cimetidine after oral administration in dogs.
Pharmaceutical research 1995;12(5):780-6.
1995: Bleske B E; Welage L S; Rose S; Amidon G L; Shea M J
The effect of dosage release formulations on the pharmacokinetics of propranolol stereoisomers in humans.
Journal of clinical pharmacology 1995;35(4):374-8.
1995: Amidon G L; Lennernäs H; Shah V P; Crison J R
A theoretical basis for a biopharmaceutic drug classification: the correlation of in vitro drug product dissolution and in vivo bioavailability.
Pharmaceutical research 1995;12(3):413-20.
1995: Polli J E; Amidon G L
In vitro characterization of sodium glycocholate binding to cholestyramine resin.
Journal of pharmaceutical sciences 1995;84(1):55-61.
1994: Yu D M; Amidon G L; Weiner N D; Fleisher D; Goldberg A H
The role of rheological properties in mucociliary transport by frog palate ciliated model.
Pharmaceutical research 1994;11(12):1785-91.
1994: Langguth P; Lee K M; Spahn-Langguth H; Amidon G L
Variable gastric emptying and discontinuities in drug absorption profiles: dependence of rates and extent of cimetidine absorption on motility phase and pH.
Biopharmaceutics & drug disposition 1994;15(9):719-46.
1994: Schwendeman S P; Amidon G L; Labhasetwar V; Levy R J
Modulated drug release using iontophoresis through heterogeneous cation-exchange membranes. 2. Influence of cation-exchanger content on membrane resistance and characteristic times.
Journal of pharmaceutical sciences 1994;83(10):1482-94.
1994: Yu D M; Amidon G L; Weiner N D; Goldberg A H
Viscoelastic properties of poly(ethylene oxide) solution.
Journal of pharmaceutical sciences 1994;83(10):1443-9.
1994: Yuasa H; Fleisher D; Amidon G L
Noncompetitive inhibition of cephradine uptake by enalapril in rabbit intestinal brush-border membrane vesicles: an enalapril specific inhibitory binding site on the peptide carrier.
The Journal of pharmacology and experimental therapeutics 1994;269(3):1107-11.
1993: Oh D M; Sinko P J; Amidon G L
Characterization of the oral absorption of some beta-lactams: effect of the alpha-amino side chain group.
Journal of pharmaceutical sciences 1993;82(9):897-900.
1993: Lin S Y; Amidon G L; Weiner N D; Goldberg A H
Viscoelasticity of anionic polymers and their mucociliary transport on the frog palate.
Pharmaceutical research 1993;10(3):411-7.
1993: Guo J H; Robertson R E; Amidon G L
An investigation into the mechanical and transport properties of aqueous latex films: a new hypothesis for the film-forming mechanism of aqueous dispersion system.
Pharmaceutical research 1993;10(3):405-10.
1993: Yuasa H; Amidon G L; Fleisher D
Peptide carrier-mediated transport in intestinal brush border membrane vesicles of rats and rabbits: cephradine uptake and inhibition.
Pharmaceutical research 1993;10(3):400-4.
1993: Luner P E; Amidon G L
Description and simulation of a multiple mixing tank model to predict the effect of bile sequestrants on bile salt excretion.
Journal of pharmaceutical sciences 1993;82(3):311-8.
1993: Sinko P J; Leesman G D; Amidon G L
Mass balance approaches for estimating the intestinal absorption and metabolism of peptides and analogues: theoretical development and applications.
Pharmaceutical research 1993;10(2):271-5.
1993: Oh D M; Curl R L; Amidon G L
Estimating the fraction dose absorbed from suspensions of poorly soluble compounds in humans: a mathematical model.
Pharmaceutical research 1993;10(2):264-70.
1992: Guo J H; Robertson R E; Amidon G L
Thermodynamic aspects of the disappearance of antiplasticization in slightly plasticized polymer films at high temperature.
Journal of pharmaceutical sciences 1992;81(12):1229-30.
1992: Chu J S; Yu D M; Amidon G L; Weiner N D; Goldberg A H
Viscoelastic properties of polyacrylic acid gels in mixed solvents.
Pharmaceutical research 1992;9(12):1659-63.
1992: Oh D-M; Sinko P J; Amidon G L
Characterization of the oral absorption of several aminopenicillins: determination of intrinsic membrane absorption parameters in the rat intestine in situ.
International journal of pharmaceutics 1992;85(1-3):181-7.
1992: Bleske B E; Warren E W; Rice T L; Shea M J; Amidon G; Knight P
Comparison of intravenous and intranasal administration of epinephrine during CPR in a canine model.
Annals of emergency medicine 1992;21(9):1125-30.
1992: Bai J P; Amidon G L
Structural specificity of mucosal-cell transport and metabolism of peptide drugs: implication for oral peptide drug delivery.
Pharmaceutical research 1992;9(8):969-78.
1992: Luner P E; Amidon G L
Equilibrium and kinetic factors influencing bile sequestrant efficacy.
Pharmaceutical research 1992;9(5):670-6.
1992: Bai J P; Hu M; Subramanian P; Mosberg H I; Amidon G L
Utilization of peptide carrier system to improve intestinal absorption: targeting prolidase as a prodrug-converting enzyme.
Journal of pharmaceutical sciences 1992;81(2):113-6.
1991: Lui C Y; Amidon G L; Goldberg A
Intranasal absorption of flurazepam, midazolam, and triazolam in dogs.
Journal of pharmaceutical sciences 1991;80(12):1125-9.
1991: Guo J H; Robertson R E; Amidon G L
Influence of physical aging on mechanical properties of polymer free films: the prediction of long-term aging effects on the water permeability and dissolution rate of polymer film-coated tablets.
Pharmaceutical research 1991;8(12):1500-4.
1991: Chu J S; Chandrasekharan R; Amidon G L; Weiner N D; Goldberg A H
Viscometric study of polyacrylic acid systems as mucoadhesive sustained-release gels.
Pharmaceutical research 1991;8(11):1408-12.
1991: Chu J S; Amidon G L; Weiner N D; Goldberg A H
Mixture experimental design in the development of a mucoadhesive gel formulation.
Pharmaceutical research 1991;8(11):1401-7.
1991: Amidon G L; DeBrincat G A; Najib N
Effects of gravity on gastric emptying, intestinal transit, and drug absorption.
Journal of clinical pharmacology 1991;31(10):968-73.
1991: Ahn H Y; Amidon G L; Smith D E
Stereoselective systemic disposition of ibuprofen enantiomers in the dog.
Pharmaceutical research 1991;8(9):1186-90.
1991: Sinko P J; Leesman G D; Amidon G L
Predicting fraction dose absorbed in humans using a macroscopic mass balance approach.
Pharmaceutical research 1991;8(8):979-88.
1991: Sinko C M; Yee A F; Amidon G L
Prediction of physical aging in controlled-release coatings: the application of the relaxation coupling model to glassy cellulose acetate.
Pharmaceutical research 1991;8(6):698-705.
1991: Choi H K; Amidon G L; Flynn G L
Some general influences of n-decylmethyl sulfoxide on the permeation of drugs across hairless mouse skin.
The Journal of investigative dermatology 1991;96(6):822-6.
1991: Bai P F; Subramanian P; Mosberg H I; Amidon G L
Structural requirements for the intestinal mucosal-cell peptide transporter: the need for N-terminal alpha-amino group.
Pharmaceutical research 1991;8(5):593-9.
1991: Kou J H; Fleisher D; Amidon G L
Calculation of the aqueous diffusion layer resistance for absorption in a tube: application to intestinal membrane permeability determination.
Pharmaceutical research 1991;8(3):298-305.
1991: Friedman D I; Amidon G L
Oral absorption of peptides: influence of pH and inhibitors on the intestinal hydrolysis of leu-enkephalin and analogues.
Pharmaceutical research 1991;8(1):93-6.
1990: Choi H K; Flynn G L; Amidon G L
Transdermal delivery of bioactive peptides: the effect of n-decylmethyl sulfoxide, pH, and inhibitors on enkephalin metabolism and transport.
Pharmaceutical research 1990;7(11):1099-106.
1990: Oberle R L; Chen T S; Lloyd C; Barnett J L; Owyang C; Meyer J; Amidon G L
The influence of the interdigestive migrating myoelectric complex on the gastric emptying of liquids.
Gastroenterology 1990;99(5):1275-82.
1990: Donovan M D; Flynn G L; Amidon G L
Absorption of polyethylene glycols 600 through 2000: the molecular weight dependence of gastrointestinal and nasal absorption.
Pharmaceutical research 1990;7(8):863-8.
1990: Donovan M D; Flynn G L; Amidon G L
The molecular weight dependence of nasal absorption: the effect of absorption enhancers.
Pharmaceutical research 1990;7(8):808-15.
1990: Sinko C M; Yee A F; Amidon G L
The effect of physical aging on the dissolution rate of anionic polyelectrolytes.
Pharmaceutical research 1990;7(6):648-53.
1989: Friedman D I; Amidon G L
Passive and carrier-mediated intestinal absorption components of two angiotensin converting enzyme (ACE) inhibitor prodrugs in rats: enalapril and fosinopril.
Pharmaceutical research 1989;6(12):1043-7.
1989: Friedman D I; Amidon G L
Intestinal absorption mechanism of dipeptide angiotensin converting enzyme inhibitors of the lysyl-proline type: lisinopril and SQ 29,852.
Journal of pharmaceutical sciences 1989;78(12):995-8.
1989: Sinko P J; Amidon G L
Characterization of the oral absorption of beta-lactam antibiotics. II. Competitive absorption and peptide carrier specificity.
Journal of pharmaceutical sciences 1989;78(9):723-7.
1989: Hu M; Subramanian P; Mosberg H I; Amidon G L
Use of the peptide carrier system to improve the intestinal absorption of L-alpha-methyldopa: carrier kinetics, intestinal permeabilities, and in vitro hydrolysis of dipeptidyl derivatives of L-alpha-methyldopa.
Pharmaceutical research 1989;6(1):66-70.
1988: Hu M; Amidon G L
Passive and carrier-mediated intestinal absorption components of captopril.
Journal of pharmaceutical sciences 1988;77(12):1007-11.
1988: Amidon G L; Sinko P J; Fleisher D
Estimating human oral fraction dose absorbed: a correlation using rat intestinal membrane permeability for passive and carrier-mediated compounds.
Pharmaceutical research 1988;5(10):651-4.
1988: Sinko P J; Amidon G L
Characterization of the oral absorption of beta-lactam antibiotics. I. Cephalosporins: determination of intrinsic membrane absorption parameters in the rat intestine in situ.
Pharmaceutical research 1988;5(10):645-50.
1988: Kou J H; Amidon G L; Lee P I
pH-dependent swelling and solute diffusion characteristics of poly(hydroxyethyl methacrylate-co-methacrylic acid) hydrogels.
Pharmaceutical research 1988;5(9):592-7.
1988: McNamara D P; Amidon G L
Reaction plane approach for estimating the effects of buffers on the dissolution rate of acidic drugs.
Journal of pharmaceutical sciences 1988;77(6):511-7.
1988: Johnson D A; Amidon G L
Determination of intrinsic membrane transport parameters from perfused intestine experiments: a boundary layer approach to estimating the aqueous and unbiased membrane permeabilities.
Journal of theoretical biology 1988;131(1):93-106.
1988: Hu M; Sinko P J; deMeere A L; Johnson D A; Amidon G L
Membrane permeability parameters for some amino acids and beta-lactam antibiotics: application of the boundary layer approach.
Journal of theoretical biology 1988;131(1):107-14.
1988: Williams N A; Amidon G L
The estimation of solubility in binary solvents: application of the reduced 3-suffix solubility equation to ethanol-water mixtures.
Pharmaceutical research 1988;5(3):193-5.
1987: Oberle R L; Amidon G L
The influence of variable gastric emptying and intestinal transit rates on the plasma level curve of cimetidine; an explanation for the double peak phenomenon.
Journal of pharmacokinetics and biopharmaceutics 1987;15(5):529-44.
1986: Fleisher D; Johnson K C; Stewart B H; Amidon G L
Oral absorption of 21-corticosteroid esters: a function of aqueous stability and intestinal enzyme activity and distribution.
Journal of pharmaceutical sciences 1986;75(10):934-9.
1986: Lui C Y; Oberle R; Fleisher D; Amidon G L
Application of a radiotelemetric system to evaluate the performance of enteric coated and plain aspirin tablets.
Journal of pharmaceutical sciences 1986;75(5):469-74.

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