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Sebastian Amigorena

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Elodie Segura; Mélanie Durand; Sebastian Amigorena
Similar antigen cross-presentation capacity and phagocytic functions in all freshly isolated human lymphoid organ-resident dendritic cells.
Elodie Segura; Vassili Soumelis; Maxime Touzot; Armelle Bohineust; Antonio Cappuccio; Gilles Chiocchia; Marc Dalod; Anne Hosmalin; Sebastian Amigorena
Human inflammatory dendritic cells induce Th17 cell differentiation.
Fiorella Kotsias; Sebastian Amigorena; Eik Hoffmann; Ariel Savina
Reactive oxygen species production in the phagosome: impact on antigen presentation in dendritic cells.

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All Publications

2013: Elodie Segura; Mélanie Durand; Sebastian Amigorena
Similar antigen cross-presentation capacity and phagocytic functions in all freshly isolated human lymphoid organ-resident dendritic cells.
The Journal of experimental medicine 2013;210(5):1035-47.
2013: Elodie Segura; Vassili Soumelis; Maxime Touzot; Armelle Bohineust; Antonio Cappuccio; Gilles Chiocchia; Marc Dalod; Anne Hosmalin; Sebastian Amigorena
Human inflammatory dendritic cells induce Th17 cell differentiation.
Immunity 2013;38(2):336-48.
2013: Fiorella Kotsias; Sebastian Amigorena; Eik Hoffmann; Ariel Savina
Reactive oxygen species production in the phagosome: impact on antigen presentation in dendritic cells.
Antioxidants & redox signaling 2013;18(6):714-29.
2013: Adriana R Mantegazza; Sebastian Amigorena; Joao G Magalhaes; Michael S Marks
Presentation of phagocytosed antigens by MHC class I and II.
Traffic (Copenhagen, Denmark) 2013;14(2):135-52.
2012: Elina Zueva; Rhys S Allan; Geneviève Almouzni; Gabrielle T Belz; Florence Cammas; Christèle Maison; Vanessa Masson; Jean-Pierre Quivy; Danièle Roche; Heidi A Schreiber; Sebastian Amigorena
[Epigenetic control of Th2 helper cell differentiation by the Suv39h1/HP1α pathway].
Médecine sciences : M/S 2012;28(12):1032-4.
2012: Luigia Pace; Tim D. Sparwasser; Andy Tempez; Catharina Arnold-Schrauf; Philippe Bousso; Luc Fetler; Fabrice Lemaitre; Sebastian Amigorena
Regulatory T cells increase the avidity of primary CD8+ T cell responses and promote memory.
Science (New York, N.Y.) 2012;338(6106):532-6.
2012: Eik Hoffmann; Fiorella Kotsias; Ariel Savina; Géraldine Visentin; Pierre Bruhns; Sebastian Amigorena
Autonomous phagosomal degradation and antigen presentation in dendritic cells.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(36):14556-61.
2012: Olivier P Joffre; Ariel Savina; Elodie Segura; Sebastian Amigorena
Cross-presentation by dendritic cells.
Nature reviews. Immunology 2012;12(8):557-69.
2012: Rhys S Allan; Geneviève Almouzni; Gabrielle T Belz; Florence Cammas; Christèle Maison; Vanessa Masson; Jean-Pierre Quivy; Danièle Roche; Heidi A Schreiber; Elina Zueva; Sebastian Amigorena
An epigenetic silencing pathway controlling T helper 2 cell lineage commitment.
Nature 2012;487(7406):249-53.
2012: Elodie Segura; Vassili Soumelis; Jenny Valladeau-Guilemond; Marie-Hélène Donnadieu; Xavier Sastre-Garau; Sebastian Amigorena
Characterization of resident and migratory dendritic cells in human lymph nodes.
The Journal of experimental medicine 2012;209(4):653-60.
2011: Juan Sabatte; Michel Thépaut; Federico Remes Lenicov; Christian Rodríguez Rodrígues; Fernando Arenzana-Seisdedos; Ana Ceballos; Wolfgang Faigle; Marisa Fernández; Franck Fieschi; Jorge Geffner; Hugues Lortat-Jacob; Emilio Malchiodi; Jean-Claude Michalski; Willy Morelle; Sebastian Amigorena
Semen clusterin is a novel DC-SIGN ligand.
Journal of immunology (Baltimore, Md. : 1950) 2011;187(10):5299-309.
2011: Laurence Zitvogel; Sebastian Amigorena; Jean-Luc Teillaud
[About Ralph M. Steinman and dendritic cells].
Médecine sciences : M/S 2011;27(11):1028-34.
2011: Ingrid S Zeelenberg; Sebastian Amigorena; Alexandre Boissonnas; Martijn H M G M den Brok; Carl G Figdor; Eric J R Jansen; Clotilde Théry; Alie van der Schaaf; Maaike A Van Hout-Kuijer; Wendy W C van Maren; Jori A L Wagenaars; Gosse J Adema
Antigen localization controls T cell-mediated tumor immunity.
Journal of immunology (Baltimore, Md. : 1950) 2011;187(3):1281-8.
2010: Vanessa Contreras; Céline Urien; Rachel Guiton; Yannick Alexandre; Thien-Phong Vu Manh; THIBAULT ANDRIEU; Karine Crozat; Luc Jouneau; Nicolas Bertho; Mathieu Epardaud; Jayne Hope; Ariel Savina; Sebastian Amigorena; Michel Bonneau; Marc Dalod; Isabelle Schwartz-Cornil
Existence of CD8α-like dendritic cells with a conserved functional specialization and a common molecular signature in distant mammalian species.
Journal of immunology (Baltimore, Md. : 1950) 2010;185(6):3313-25.
2010: Alexandre Boissonnas; Alix Scholer-Dahirel; Virginie Simon-Blancal; Luigia Pace; Fabien Valet; adrien kissenpfennig; Tim D. Sparwasser; Bernard Malissen; Luc Fetler; Sebastian Amigorena
Foxp3+ T cells induce perforin-dependent dendritic cell death in tumor-draining lymph nodes.
Immunity 2010;32(2):266-78.
2010: Sebastian Amigorena; Ariel Savina
Intracellular mechanisms of antigen cross presentation in dendritic cells.
Current opinion in immunology 2010;22(1):109-17.
2010: Matias Ostrowski; Nuno B Carmo; Sophie Krumeich; Isabelle Fanget; Graça Raposo; Ariel Savina; Catarina F Moita; Kristine Schauer; Alistair N Hume; Rui P Freitas; Bruno Goud; Philippe Benaroch; Nir Hacohen; Mitsunori Fukuda; Claire Desnos; Miguel C Seabra; François Darchen; Sebastian Amigorena; Luis F Moita; Clotilde Thery
Rab27a and Rab27b control different steps of the exosome secretion pathway.
Nature cell biology 2010;12(1):19-30; sup pp 1-13.
2010: Ariel Savina; P VARGAS; Pierre Guermonprez; Ana-Maria Lennon; Sebastian Amigorena
Measuring pH, ROS production, maturation, and degradation in dendritic cell phagosomes using cytofluorometry-based assays.
Methods in molecular biology (Clifton, N.J.) 2010;595():383-402.
2009: Fernando E Sepulveda; Sophia Maschalidi; Renaud Colisson; Lea Heslop; Cristina Ghirelli; Emna Sakka; Ana-Maria Lennon-Duménil; Sebastian Amigorena; Lucien Cabanie; Bénédicte Manoury
Critical role for asparagine endopeptidase in endocytic Toll-like receptor signaling in dendritic cells.
Immunity 2009;31(5):737-48.
2009: Laurence Bougnères; Julie Helft; sangeeta tiwari; P VARGAS; Benny Hung-Junn Chang; Lawrence Chan; Laura Campisi; Gregoire Lauvau; Stéphanie Hugues; Pradeep Kumar; Alice O Kamphorst; Ana-Maria Lennon Dumenil; Michel C Nussenzweig; John D MacMicking; Sebastian Amigorena; Pierre Guermonprez
A role for lipid bodies in the cross-presentation of phagocytosed antigens by MHC class I in dendritic cells.
Immunity 2009;31(2):232-44.
2009: Ariel Savina; Audrey Peres; Ignacio Cebrian; Nuno Carmo; Catarina Moita; Nir Hacohen; Luis F Moita; Sebastian Amigorena
The small GTPase Rac2 controls phagosomal alkalinization and antigen crosspresentation selectively in CD8(+) dendritic cells.
Immunity 2009;30(4):544-55.
2009: Ken Coppieters; Ana María Barral; Amy Juedes; Tom Wolfe; Evelyn Rodrigo; Clotilde Théry; Sebastian Amigorena; Matthias G von Herrath
No significant CTL cross-priming by dendritic cell-derived exosomes during murine lymphocytic choriomeningitis virus infection.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(4):2213-20.
2009: Hidde Ploegh; Sebastian Amigorena
Editorial overview.
Current opinion in immunology 2009;21(1):68-9.
2009: Florence Faure; Adriana Mantegazza; Charlotte Sadaka; Christine Sedlik; Francine Jotereau; Sebastian Amigorena
Long-lasting cross-presentation of tumor antigen in human DC.
European journal of immunology 2009;39(2):380-90.
2009: Alexandre Boissonnas; Alix Scholer-Dahire; Luc Fetler; Sebastian Amigorena
Multiphoton imaging of cytotoxic T lymphocyte-mediated antitumor immune responses.
Current topics in microbiology and immunology 2009;334():265-87.
2008: Adriana R Mantegazza; Ariel Savina; Mónica Vermeulen; Laura Pérez; Jorge Geffner; Olivier Hermine; Sergio D Rosenzweig; Florence Faure; Sebastian Amigorena
NADPH oxidase controls phagosomal pH and antigen cross-presentation in human dendritic cells.
Blood 2008;112(12):4712-22.
2008: Cinzia Nobile; Marianne Lind; Francesc Miro; Karine Chemin; Marie Tourret; Giovanni Occhipinti; Stéphanie Dogniaux; Sebastian Amigorena; Claire Hivroz
Cognate CD4+ T-cell-dendritic cell interactions induce migration of immature dendritic cells through dissolution of their podosomes.
Blood 2008;111(7):3579-90.
2008: Elisa Tagliani; Pierre Guermonprez; Jorge Sepúlveda; María López-Bravo; Carlos Ardavín; Sebastian Amigorena; Federica Benvenuti; Oscar R. Burrone
Selection of an antibody library identifies a pathway to induce immunity by targeting CD36 on steady-state CD8 alpha+ dendritic cells.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(5):3201-9.
2008: Ingrid S Zeelenberg; Matias Ostrowski; Sophie Krumeich; Angélique Bobrie; Carolina Jancic; Alexandre Boissonnas; Alain Delcayre; Jean-Bernard Le Pecq; Béhazine Combadière; Sebastian Amigorena; Clotilde Théry
Targeting tumor antigens to secreted membrane vesicles in vivo induces efficient antitumor immune responses.
Cancer research 2008;68(4):1228-35.
2008: Alix Scholer; Stéphanie Hugues; Alexandre Boissonnas; Luc Fetler; Sebastian Amigorena
Intercellular adhesion molecule-1-dependent stable interactions between T cells and dendritic cells determine CD8+ T cell memory.
Immunity 2008;28(2):258-70.
2007: Juan Sabatté; Ana Ceballos; Silvina Raiden; Mónica Vermeulen; Karen Nahmod; Julián Maggini; Gabriela Salamone; Horacio Salomón; Sebastian Amigorena; Jorge Geffner
Human seminal plasma abrogates the capture and transmission of human immunodeficiency virus type 1 to CD4+ T cells mediated by DC-SIGN.
Journal of virology 2007;81(24):13723-34.
2007: Ariel Savina; Sebastian Amigorena
Phagocytosis and antigen presentation in dendritic cells.
Immunological reviews 2007;219():143-56.
2007: Lionel Apetoh; François Ghiringhelli; Antoine Tesniere; Michel Obeid; Carla Ortiz; Alfredo Criollo; Grégoire Mignot; M Chiara Maiuri; Evelyn Ullrich; Patrick Saulnier; Huan Yang; Sebastian Amigorena; Bernhard RYFFEL; Franck J Barrat; Paul Saftig; Francis Levi; Rosette Lidereau; Catherine Nogues; Jean-Paul Mira; Agnès Chompret; Virginie Joulin; Françoise Clavel-Chapelon; Jean Bourhis; Fabrice André; Suzette Delaloge; Thomas Tursz; Guido Kroemer; Laurence Zitvogel
Toll-like receptor 4-dependent contribution of the immune system to anticancer chemotherapy and radiotherapy.
Nature medicine 2007;13(9):1050-9.
2007: Stéphanie Hugues; Alix Scholer; Alexandre Boissonnas; Alexander Nussbaum; Christophe Combadière; Sebastian Amigorena; Luc Fetler
Dynamic imaging of chemokine-dependent CD8+ T cell help for CD8+ T cell responses.
Nature immunology 2007;8(9):921-30.
2007: Diego Martínez; Mónica Vermeulen; Erika von Euw; Juan Sabatté; Julian Maggíni; Ana Ceballos; Analía Trevani; Karen Nahmod; Gabriela Salamone; María Marcela Barrio; Mirta Giordano; Sebastian Amigorena; Jorge Geffner
Extracellular acidosis triggers the maturation of human dendritic cells and the production of IL-12.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(3):1950-9.
2007: Elodie Segura; Coralie Guérin; Nancy Hogg; Sebastian Amigorena; Clotilde Théry
CD8+ dendritic cells use LFA-1 to capture MHC-peptide complexes from exosomes in vivo.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(3):1489-96.
2007: Alexandre Boissonnas; Luc Fetler; Sebastian Amigorena
[Stepwise strategy adopted by cytotoxic T cells to eliminate solid tumors].
Médecine sciences : M/S 2007;23(6-7):570-2.
2007: Carolina Jancic; Ariel Savina; Christina Wasmeier; Tanya Tolmachova; Jamel El Benna; Pham My-Chan Dang; Steve Pascolo; Marie-Anne Gougerot-Pocidalo; Graça Raposo; Miguel C Seabra; Sebastian Amigorena
Rab27a regulates phagosomal pH and NADPH oxidase recruitment to dendritic cell phagosomes.
Nature cell biology 2007;9(4):367-78.
2007: Alexandre Boissonnas; Luc Fetler; Ingrid S Zeelenberg; Stéphanie Hugues; Sebastian Amigorena
In vivo imaging of cytotoxic T cell infiltration and elimination of a solid tumor.
The Journal of experimental medicine 2007;204(2):345-56.
2006: Francesc Miro; Cinzia Nobile; Nicolas Blanchard; Marianne Lind; Orchidée Filipe-Santos; Claire Fieschi; Ariane Chapgier; Guillaume Vogt; Ludovic de Beaucoudrey; Dinakantha S Kumararatne; Françoise Le Deist; Jean-Laurent Casanova; Sebastian Amigorena; Claire Hivroz
T cell-dependent activation of dendritic cells requires IL-12 and IFN-gamma signaling in T cells.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(6):3625-34.
2006: Nathalie Chaput; Caroline Flament; Sophie Viaud; Julien Taieb; Stephan Roux; Alain Spatz; Fabrice André; Jean-Bernard LePecq; Muriel Boussac; Jérôme Garin; Sebastian Amigorena; Clotilde Théry; Laurence Zitvogel
Dendritic cell derived-exosomes: biology and clinical implementations.
Journal of leukocyte biology 2006;80(3):471-8.
2006: Sebastian Amigorena
Immunological techniques: imaging immune responses in vivo.
Current opinion in immunology 2006;18(4):473-5.
2006: Stéphanie Hugues; Alexandre Boissonnas; Sebastian Amigorena; Luc Fetler
The dynamics of dendritic cell-T cell interactions in priming and tolerance.
Current opinion in immunology 2006;18(4):491-5.
2006: Ariel Savina; Carolina Jancic; Stéphanie Hugues; Pierre Guermonprez; P VARGAS; Ivan C Moura; Ana-Maria Lennon-Duménil; Miguel C Seabra; Graça Raposo; Sebastian Amigorena
NOX2 controls phagosomal pH to regulate antigen processing during crosspresentation by dendritic cells.
Cell 2006;126(1):205-18.
2006: Clotilde Théry; Sebastian Amigorena; Graça Raposo; Aled Clayton
Isolation and characterization of exosomes from cell culture supernatants and biological fluids.
Current protocols in cell biology / editorial board, Juan S. Bonifacino ... [et al.] 2006;Chapter 3():Unit 3.22.
2005: Elodie Segura; Sebastian Amigorena; Clotilde Théry
Mature dendritic cells secrete exosomes with strong ability to induce antigen-specific effector immune responses.
Blood cells, molecules & diseases 2005;35(2):89-93.
2005: Philippe Véron; Elodie Segura; Gaël Sugano; Sebastian Amigorena; Clotilde Théry
Accumulation of MFG-E8/lactadherin on exosomes from immature dendritic cells.
Blood cells, molecules & diseases 2005;35(2):81-8.
2005: Jean-Sébastien Silvestre; Clotilde Théry; Bernard I Lévy; Alain Tedgui; Sebastian Amigorena; Ziad Mallat
[Lactadherin promotes VEGF-dependent neovascularization].
Médecine sciences : M/S 2005;21(8-9):683-5.
2005: Luc Fetler; Sebastian Amigorena
Neuroscience. Brain under surveillance: the microglia patrol.
Science (New York, N.Y.) 2005;309(5733):392-3.
2005: Elodie Segura; Carole Nicco; Bérangère Lombard; Philippe Véron; Graça Raposo; Frédéric Batteux; Sebastian Amigorena; Clotilde Théry
ICAM-1 on exosomes from mature dendritic cells is critical for efficient naive T-cell priming.
Blood 2005;106(1):216-23.
2005: Jean-Sébastien Silvestre; Clotilde Théry; Ghislaine Hamard; Jacques Boddaert; Barbara Aguilar; Alain Delcayre; Christophe Houbron; Radia Tamarat; Olivier Blanc-Brude; Sylvia Heeneman; Michel Clergue; Micheline Duriez; Régine Merval; Bernard I Lévy; Alain Tedgui; Sebastian Amigorena; Ziad Mallat
Lactadherin promotes VEGF-dependent neovascularization.
Nature medicine 2005;11(5):499-506.
2005: Federica Benvenuti; Stéphanie Hugues; Sebastian Amigorena
[Dendritic cell cytoskeleton mobilization to enhance antigen presentation].
Médecine sciences : M/S 2005;21(1):13-5.
2005: Pierre Guermonprez; Sebastian Amigorena
Pathways for antigen cross presentation.
Springer seminars in immunopathology 2005;26(3):257-71.
2004: Fernanda Pascutti; Milena Pitashny; Ana Lía Nocito; Pierre Guermonprez; Sebastian Amigorena; Juana Wietzerbin; Esteban Serra; Oscar Bottasso; Silvia Revelli
Benznidazole, a drug used in Chagas' disease, ameliorates LPS-induced inflammatory response in mice.
Life sciences 2004;76(6):685-97.
2004: Jacques Ninio; Sebastian Amigorena
How B cells and dendritic cells may cooperate in antigen purification.
Journal of theoretical biology 2004;231(3):309-17.
2004: Stéphanie Hugues; Luc Fetler; Laura Bonifaz; Julie Helft; François Amblard; Sebastian Amigorena
Distinct T cell dynamics in lymph nodes during the induction of tolerance and immunity.
Nature immunology 2004;5(12):1235-42.
2004: Nicolas Blanchard; Maud Decraene; Kun Yang; Francesc Miro; Sebastian Amigorena; Claire Hivroz
Strong and durable TCR clustering at the T/dendritic cell immune synapse is not required for NFAT activation and IFN-gamma production in human CD4+ T cells.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(5):3062-72.
2004: Federica Benvenuti; Stéphanie Hugues; Marita J Walmsley; Sandra Ruf; Luc Fetler; Michel Popoff; Victor L J Tybulewicz; Sebastian Amigorena
Requirement of Rac1 and Rac2 expression by mature dendritic cells for T cell priming.
Science (New York, N.Y.) 2004;305(5687):1150-3.
2004: Fabrice André; Nathalie Chaput; Noël Emile Célestin Schartz; Caroline Flament; Nathalie Aubert; Jacky Bernard; François Lemonnier; Graça Raposo; Bernard Escudier; Di-Hwei Hsu; Thomas Tursz; Sebastian Amigorena; Eric Angevin; Laurence Zitvogel
Exosomes as potent cell-free peptide-based vaccine. I. Dendritic cell-derived exosomes transfer functional MHC class I/peptide complexes to dendritic cells.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(4):2126-36.
2004: Beatriz C Gil-Torregrosa; Ana-Maria Lennon-Duménil; Benedikt Kessler; Pierre Guermonprez; Hidde L Ploegh; Doriana Fruci; Peter van Endert; Sebastian Amigorena
Control of cross-presentation during dendritic cell maturation.
European journal of immunology 2004;34(2):398-407.
2004: Pierre Guermonprez; Sebastian Amigorena
[An export-reimport model for cross presentation of particulate antigens by MHC class I molecules in dentritic cells].
Journal de la Société de biologie 2004;198(2):121-2.
2004: Federica Benvenuti; Cecile Lagaudrière-Gesbert; Isabelle Grandjean; Carolina Jancic; Claire Hivroz; Alain Trautmann; Olivier Lantz; Sebastian Amigorena
Dendritic cell maturation controls adhesion, synapse formation, and the duration of the interactions with naive T lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(1):292-301.
2003: Béatrice Riteau; Florence Faure; Catherine Menier; Sophie Viel; Edgardo D Carosella; Sebastian Amigorena; Nathalie Rouas-Freiss
Exosomes bearing HLA-G are released by melanoma cells.
Human immunology 2003;64(11):1064-72.
2003: Sebastian Amigorena
Y in X priming.
Nature immunology 2003;4(11):1047-8.
2003: Pierre Guermonprez; Loredana Saveanu; Monique J Kleijmeer; Jean Davoust; Peter van Endert; Sebastian Amigorena
ER-phagosome fusion defines an MHC class I cross-presentation compartment in dendritic cells.
Nature 2003;425(6956):397-402.
2003: Peck Szee Tan; Amanda Gavin; Nadine Barnes; Duane W Sears; David Vremec; Ken Shortman; Sebastian Amigorena; Patricia L Mottram; P Mark Hogarth
Unique monoclonal antibodies define expression of Fc gamma RI on macrophages and mast cell lines and demonstrate heterogeneity among subcutaneous and other dendritic cells.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(5):2549-56.
2003: Christine Sedlik; Daniel Orbach; Philippe Véron; Edina Schweighoffer; Francesco Colucci; Romina Gamberale; Andreea Ioan-Facsinay; Sjef Verbeek; Paola Ricciardi-Castagnoli; Christian Bonnerot; Victor L J Tybulewicz; James P Di Santo; Sebastian Amigorena
A critical role for Syk protein tyrosine kinase in Fc receptor-mediated antigen presentation and induction of dendritic cell maturation.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(2):846-52.
2002: Fabrice André; Noël Emile Célestin Schartz; Nathalie Chaput; Caroline Flament; Graça Raposo; Sebastian Amigorena; Eric Angevin; Laurence Zitvogel
Tumor-derived exosomes: a new source of tumor rejection antigens.
Vaccine 2002;20 Suppl 4():A28-31.
2002: Clotilde Théry; Livine Duban; Elodie Segura; Philippe Véron; Olivier Lantz; Sebastian Amigorena
Indirect activation of naïve CD4+ T cells by dendritic cell-derived exosomes.
Nature immunology 2002;3(12):1156-62.
2002: Clotilde Théry; Laurence Zitvogel; Sebastian Amigorena
Exosomes: composition, biogenesis and function.
Nature reviews. Immunology 2002;2(8):569-79.
2002: Emmanuelle Le Roy; Michel Baron; Wolfgang Faigle; Danièle Clément; David M Lewinsohn; Daniel N Streblow; Jay A Nelson; Sebastian Amigorena; Jean-Luc Davignon
Infection of APC by human cytomegalovirus controlled through recognition of endogenous nuclear immediate early protein 1 by specific CD4(+) T lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(3):1293-301.
2002: Fabrice Andre; Noël Emile Célestin Schartz; Mojgan Movassagh; Caroline Flament; Patricia Pautier; Philippe Morice; Christophe Pomel; Catherine Lhomme; Bernard Escudier; Thierry Le Chevalier; Thomas Tursz; Sebastian Amigorena; Graça Raposo; Eric Angevin; Laurence Zitvogel
Malignant effusions and immunogenic tumour-derived exosomes.
Lancet 2002;360(9329):295-305.
2002: Andreea Ioan-Facsinay; Sjef De Kimpe; S M M Hellwig; P L van Lent; Frans M A Hofhuis; H H van Ojik; Christine Sedlik; S A da Silveira; J Gerber; Y F de Jong; R Roozendaal; L A Aarden; W B van den Berg; Takashi Saito; David Mosser; Sebastian Amigorena; Shozo Izui; Gert-Jan B van Ommen; Martine J van Vugt; Jan G J van de Winkel; Sjef Verbeek
FcgammaRI (CD64) contributes substantially to severity of arthritis, hypersensitivity responses, and protection from bacterial infection.
Immunity 2002;16(3):391-402.
2002: Sebastian Amigorena
Fc gamma receptors and cross-presentation in dendritic cells.
The Journal of experimental medicine 2002;195(1):F1-3.
2002: Pierre Guermonprez; Jenny Valladeau; Laurence Zitvogel; Clotilde Théry; Sebastian Amigorena
Antigen presentation and T cell stimulation by dendritic cells.
Annual review of immunology 2002;20():621-67.
2001: Clotilde Théry; Muriel Boussac; Philippe Véron; Paola Ricciardi-Castagnoli; Graça Raposo; Jérôme Garin; Sebastian Amigorena
Proteomic analysis of dendritic cell-derived exosomes: a secreted subcellular compartment distinct from apoptotic vesicles.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(12):7309-18.
2001: J Wolfers; A Lozier; Graça Raposo; Armelle Regnault; Clotilde Théry; Carole Masurier; Caroline Flament; S Pouzieux; Florence Faure; Thomas Tursz; Eric Angevin; Sebastian Amigorena; Laurence Zitvogel
Tumor-derived exosomes are a source of shared tumor rejection antigens for CTL cross-priming.
Nature medicine 2001;7(3):297-303.
2001: Clotilde Théry; Sebastian Amigorena
The cell biology of antigen presentation in dendritic cells.
Current opinion in immunology 2001;13(1):45-51.
2001: Fabrice Andre; M Andersen; J Wolfers; A Lozier; Graça Raposo; V Serra; C Ruegg; Caroline Flament; Eric Angevin; Sebastian Amigorena; Laurence Zitvogel
Exosomes in cancer immunotherapy: preclinical data.
Advances in experimental medicine and biology 2001;495():349-54.
2001: Sebastian Amigorena
[Exosomes derived from dendritic cells].
Journal de la Société de biologie 2001;195(1):25-7.
2000: Wolfgang Faigle; Emma Colucci-Guyon; Daniel Louvard; Sebastian Amigorena; Thierry Galli
Vimentin filaments in fibroblasts are a reservoir for SNAP23, a component of the membrane fusion machinery.
Molecular biology of the cell 2000;11(10):3485-94.
2000: Nacilla Haicheur; E Bismuth; S Bosset; Olivier Adotevi; Guy Warnier; V Lacabanne; Armelle Regnault; Catherine Desaymard; Sebastian Amigorena; Paola Ricciardi-Castagnoli; B Goud; Wolf H Fridman; Ludger Johannes; Eric Tartour
The B subunit of Shiga toxin fused to a tumor antigen elicits CTL and targets dendritic cells to allow MHC class I-restricted presentation of peptides derived from exogenous antigens.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(6):3301-8.
2000: Sebastian Amigorena
Cancer immunotherapy using dendritic cell-derived exosomes.
Medicina 2000;60 Suppl 2():51-4.
1999: Sebastian Amigorena; Christian Bonnerot
Fc receptor signaling and trafficking: a connection for antigen processing.
Immunological reviews 1999;172():279-84.
1999: Sebastian Amigorena; Christian Bonnerot
Fc receptors for IgG and antigen presentation on MHC class I and class II molecules.
Seminars in immunology 1999;11(6):385-90.
1999: Clotilde Théry; Armelle Regnault; Jérôme Garin; J Wolfers; Laurence Zitvogel; Paola Ricciardi-Castagnoli; Graça Raposo; Sebastian Amigorena
Molecular characterization of dendritic cell-derived exosomes. Selective accumulation of the heat shock protein hsc73.
The Journal of cell biology 1999;147(3):599-610.
1999: A Rodriguez; Armelle Regnault; Monique J Kleijmeer; Paola Ricciardi-Castagnoli; Sebastian Amigorena
Selective transport of internalized antigens to the cytosol for MHC class I presentation in dendritic cells.
Nature cell biology 1999;1(6):362-8.
1999: Valerie Brachet; G Péhau-Arnaudet; Catherine Desaymard; Graça Raposo; Sebastian Amigorena
Early endosomes are required for major histocompatiblity complex class II transport to peptide-loading compartments.
Molecular biology of the cell 1999;10(9):2891-904.
1999: Laurence Zitvogel; Nadine C Fernandez; A Lozier; J Wolfers; Armelle Regnault; Graça Raposo; Sebastian Amigorena
Dendritic cells or their exosomes are effective biotherapies of cancer.
European journal of cancer (Oxford, England : 1990) 1999;35 Suppl 3():S36-8.
1999: Frederic Geissmann; Patrick Revy; Armelle Regnault; yves lepelletier; Michel Dy; N Brousse; Sebastian Amigorena; O Hermine; Anne Durandy
TGF-beta 1 prevents the noncognate maturation of human dendritic Langerhans cells.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(8):4567-75.
1999: Armelle Regnault; Danielle Lankar; V Lacabanne; A Rodriguez; Clotilde Théry; Maria Rescigno; T Saito; S Verbeek; Christian Bonnerot; Paola Ricciardi-Castagnoli; Sebastian Amigorena
Fcgamma receptor-mediated induction of dendritic cell maturation and major histocompatibility complex class I-restricted antigen presentation after immune complex internalization.
The Journal of experimental medicine 1999;189(2):371-80.
1998: Sebastian Amigorena
Anti-tumour immunotherapy using dendritic-cell-derived exosomes.
Research in immunology 1998;149(7-8):661-2.
1998: Clotilde Théry; Valerie Brachet; Armelle Regnault; Maria Rescigno; Paola Ricciardi-Castagnoli; Christian Bonnerot; Sebastian Amigorena
MHC class II transport from lysosomal compartments to the cell surface is determined by stable peptide binding, but not by the cytosolic domains of the alpha- and beta-chains.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(5):2106-13.
1998: Christian Bonnerot; Volker Briken; Valerie Brachet; Danielle Lankar; S Cassard; B Jabri; Sebastian Amigorena
syk protein tyrosine kinase regulates Fc receptor gamma-chain-mediated transport to lysosomes.
The EMBO journal 1998;17(16):4606-16.
1998: Wolfgang Faigle; Graça Raposo; Danièle Tenza; VM Pinet; Anne B Vogt; Harald Kropshofer; A Fischer; G de Saint-Basile; Sebastian Amigorena
Deficient peptide loading and MHC class II endosomal sorting in a human genetic immunodeficiency disease: the Chediak-Higashi syndrome.
The Journal of cell biology 1998;141(5):1121-34.
1998: Harald Kropshofer; Anne B Vogt; C Thery; Elena Armandola; B C Li; Gerhard Moldenhauer; Sebastian Amigorena; Günter J Hämmerling
A role for HLA-DO as a co-chaperone of HLA-DM in peptide loading of MHC class II molecules.
The EMBO journal 1998;17(11):2971-81.
1998: Laurence Zitvogel; Armelle Regnault; A Lozier; J Wolfers; Caroline Flament; Danièle Tenza; Paola Ricciardi-Castagnoli; Graça Raposo; Sebastian Amigorena
Eradication of established murine tumors using a novel cell-free vaccine: dendritic cell-derived exosomes.
Nature medicine 1998;4(5):594-600.
1998: Sebastian Amigorena; Danielle Lankar; Volker Briken; L Gapin; M Viguier; Christian Bonnerot
Type II and III receptors for immunoglobulin G (IgG) control the presentation of different T cell epitopes from single IgG-complexed antigens.
The Journal of experimental medicine 1998;187(4):505-15.
1998: Sebastian Amigorena; Christian Bonnerot
Role of B-cell and Fc receptors in the selection of T-cell epitopes.
Current opinion in immunology 1998;10(1):88-92.
1997: Christian Bonnerot; Volker Briken; Sebastian Amigorena
Intracellular signaling and endosomal trafficking of immunoreceptors. Shared effectors underlying MHC class II-restricted antigen presentation.
Immunology letters 1997;57(1-3):1-4.
1997: Valerie Brachet; Graça Raposo; Sebastian Amigorena; I Mellman
Ii chain controls the transport of major histocompatibility complex class II molecules to and from lysosomes.
The Journal of cell biology 1997;137(1):51-65.
1996: Philippe Pierre; Lisa K Denzin; C Hammond; J R Drake; Sebastian Amigorena; Peter Cresswell; Ira Mellman
HLA-DM is localized to conventional and unconventional MHC class II-containing endocytic compartments.
Immunity 1996;4(3):229-39.
1995: Ira Mellman; Philippe Pierre; Sebastian Amigorena
Lonely MHC molecules seeking immunogenic peptides for meaningful relationships.
Current opinion in cell biology 1995;7(4):564-72.
1995: Sebastian Amigorena; Paul Webster; J Drake; J Newcomb; Peter Cresswell; Ira Mellman
Invariant chain cleavage and peptide loading in major histocompatibility complex class II vesicles.
The Journal of experimental medicine 1995;181(5):1729-41.
1994: Sebastian Amigorena; J R Drake; Paul Webster; Ira Mellman
Transient accumulation of new class II MHC molecules in a novel endocytic compartment in B lymphocytes.
Nature 1994;369(6476):113-20.
1994: E A Elliott; J R Drake; Sebastian Amigorena; J Elsemore; Paul Webster; Ira Mellman; Richard A Flavell
The invariant chain is required for intracellular transport and function of major histocompatibility complex class II molecules.
The Journal of experimental medicine 1994;179(2):681-94.
1993: N Rouas-Freiss; Franck Housseau; Jean-Michel Bidart; Christian Bonnerot; Sebastian Amigorena; Jean-Gérard Guillet; Dominique Bellet
Deficient antigen processing of a protein quaternary structure can be overcome by receptor-mediated uptake.
European journal of immunology 1993;23(12):3335-44.
1993: D Choquet; M Partiseti; Sebastian Amigorena; Christian Bonnerot; Wolf H Fridman; Henri Korn
Cross-linking of IgG receptors inhibits membrane immunoglobulin-stimulated calcium influx in B lymphocytes.
The Journal of cell biology 1993;121(2):355-63.
1993: Christian Bonnerot; Sebastian Amigorena
Murine low-affinity receptors for the Fc portion of IgG. Roles in cell activation and ligand internalization.
Receptors & channels 1993;1(1):73-9.
1992: Sebastian Amigorena; Jean Salamero; Jean Davoust; Wolf H Fridman; Christian Bonnerot
Tyrosine-containing motif that transduces cell activation signals also determines internalization and antigen presentation via type III receptors for IgG.
Nature 1992;358(6384):337-41.
1992: Christian Bonnerot; Sebastian Amigorena; D Choquet; R Pavlovich; V Choukroun; Wolf H Fridman
Role of associated gamma-chain in tyrosine kinase activation via murine Fc gamma RIII.
The EMBO journal 1992;11(7):2747-57.
1992: Sebastian Amigorena; Christian Bonnerot; J R Drake; D Choquet; Walter Hunziker; J G Guillet; Paul Webster; C Sautes; Ira Mellman; Wolf H Fridman
Cytoplasmic domain heterogeneity and functions of IgG Fc receptors in B lymphocytes.
Science (New York, N.Y.) 1992;256(5065):1808-12.
1992: Wolf H Fridman; Christian Bonnerot; M Daeron; Sebastian Amigorena; Jean-Luc Teillaud; C Sautes
Structural bases of Fc gamma receptor functions.
Immunological reviews 1992;125():49-76.
1992: Claire Mathiot; Sebastian Amigorena; Janine Moncuit; C Sautès; Wolf H Fridman; Jean-Luc Teillaud
In vitro inhibition of tumor B cell growth by IgG-BF-producing Fc gamma RII+ T cell hybridoma and by immunoglobulin G-binding factors.
Immunologic research 1992;11(3-4):296-304.
1992: C Sautès; N Mazières; Annie Galinha; Eric Tartour; Christian Bonnerot; Sebastian Amigorena; C Teillaud; R Spagnoli; Wolf H Fridman
Murine soluble Fc gamma receptors/IgG-binding factors (IgG-BF): analysis of the relation to Fc gamma RII and production of milligram quantities of biologically active recombinant IgG-BF.
Immunologic research 1992;11(3-4):181-90.
1991: V Malard; Sebastian Amigorena; Brigitte Bauvois; M Daeron; M A Cousin; D Lando; Wolf H Fridman; C Sautes
21.1.1, a novel activation marker of T and B cells.
Molecular immunology 1991;28(4-5):417-26.
1990: Sebastian Amigorena; D Choquet; Jean-Luc Teillaud; Henri Korn; Wolf H Fridman
Ion channels and B cell mitogenesis.
Molecular immunology 1990;27(12):1259-68.
1990: Sebastian Amigorena; Christian Bonnerot; Wolf H Fridman; Jean-Luc Teillaud
Recombinant interleukin 2-activated natural killer cells regulate IgG2a production.
European journal of immunology 1990;20(8):1781-7.
1990: Sebastian Amigorena; D Choquet; Jean-Luc Teillaud; Henri Korn; Wolf H Fridman
Ion channel blockers inhibit B cell activation at a precise stage of the G1 phase of the cell cycle. Possible involvement of K+ channels.
Journal of immunology (Baltimore, Md. : 1950) 1990;144(6):2038-45.
1990: Christian Bonnerot; Sebastian Amigorena; Wolf H Fridman; J Even; Marc Daëron
Unmethylation of specific sites in the 5' region is critical for the expression of murine alpha Fc gamma R gene.
Journal of immunology (Baltimore, Md. : 1950) 1990;144(1):323-8.
1989: Sebastian Amigorena; Christian Bonnerot; D Choquet; Wolf H Fridman; Jean-Luc Teillaud
Fc gamma RII expression in resting and activated B lymphocytes.
European journal of immunology 1989;19(8):1379-85.
1989: Jean-Luc Teillaud; S Brunati; Sebastian Amigorena; Claire Mathiot; C Sautes; Wolf H Fridman
Control of B cell function by Fc gamma receptor-positive T cells and immunoglobulin-binding factors.
Contributions to microbiology and immunology 1989;11():124-50.
1988: S Brunati; Christine Miossec; Claire Mathiot; Janine Moncuit; Sebastian Amigorena; Jean-Luc Teillaud; Wolf H Fridman
Regulatory effects of IgG-BF on hybridoma B cells. molecular characterization of variant cell lines.
Molecular immunology 1988;25(11):1133-42.
1988: Christian Bonnerot; Marc Daëron; N Varin; Sebastian Amigorena; P M Hogarth; J Even; Wolf H Fridman
Methylation in the 5' region of the murine beta Fc gamma R gene regulates the expression of Fc gamma receptor II.
Journal of immunology (Baltimore, Md. : 1950) 1988;141(3):1026-33.
1988: Jean-Luc Teillaud; Claire Mathiot; Sebastian Amigorena; S Brunati; Janine Moncuit; Wolf H Fridman
Regulation of hybridoma B-cell proliferation by immunoglobulin-binding factor.
Cancer detection and prevention 1988;12(1-6):115-23.
1987: E Thibaut; Sebastian Amigorena; Janine Moncuit; Wolf H Fridman; Jean-Luc Teillaud
Software for the quantitative evaluation of in vitro monoclonal antibody production from ELISA data.
Journal of immunological methods 1987;104(1-2):15-24.
1987: Jean-Luc Teillaud; Sebastian Amigorena; Janine Moncuit; C Sautès; Wolf H Fridman
Immunoglobulin G-binding factors (IgG-BF) inhibit IgG secretion by, as well as proliferation of, hybridoma B cells.
Immunology letters 1987;16(2):139-44.
1987: Sebastian Amigorena; Janine Moncuit; W H Fridman; Jean-Luc Teillaud
A sensitive method for testing the effect of immunoglobulin binding factor on Ig secretion by hybridoma B cells.
Journal of immunological methods 1987;97(1):57-64.
1987: Wolf H Fridman; Jean-Luc Teillaud; Sebastian Amigorena; Marc Daëron; U Blank; C Néauport-Sautès
The isotypic circuit: immunoglobulins, Fc receptors and immunoglobulin binding factors.
International reviews of immunology 1987;2(2):221-40.
1986: Wolf H Fridman; Marc Daëron; Sebastian Amigorena; C Rabourdin-Combe; C Neauport-Sautes
Bases for an isotypic network.
Molecular immunology 1986;23(11):1141-8.
1986: C Neauport-Sautes; U Blank; Marc Daëron; Annie Galinha; Jean-Luc Teillaud; Janine Moncuit; Sebastian Amigorena; Wolf H Fridman
Molecular heterogeneity of murine IgG-BF.
Molecular immunology 1986;23(11):1183-91.