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Dennis Discher

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TOP 3
Pia L Rodriguez; Richard K Tsai; David A Christian; Takamasa Harada; Diego A Pantano; Dennis E Discher
Minimal "Self" peptides that inhibit phagocytic clearance and enhance delivery of nanoparticles.
Brian C Baumann; Christina Chapman; Dennis E Discher; Takamasa Harada; Gary D Kao; Abdullah Mahmud; Joe Swift; Xiangsheng Xu; Jay F Dorsey
Enhancing the efficacy of drug-loaded nanocarriers against brain tumors by targeted radiation therapy.
Matthew Raab; Palak Shah; Jae-Won Shin; Joe Swift; P C Dave P Dingal; Dennis E Discher
Crawling from soft to stiff matrix polarizes the cytoskeleton and phosphoregulates myosin-II heavy chain.

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All Publications

2013: Pia L Rodriguez; Richard K Tsai; David A Christian; Takamasa Harada; Diego A Pantano; Dennis E Discher
Minimal "Self" peptides that inhibit phagocytic clearance and enhance delivery of nanoparticles.
Science (New York, N.Y.) 2013;339(6122):971-5.
2013: Brian C Baumann; Christina Chapman; Dennis E Discher; Takamasa Harada; Gary D Kao; Abdullah Mahmud; Joe Swift; Xiangsheng Xu; Jay F Dorsey
Enhancing the efficacy of drug-loaded nanocarriers against brain tumors by targeted radiation therapy.
Oncotarget 2013;4(1):64-79.
2012: Matthew Raab; Palak Shah; Jae-Won Shin; Joe Swift; P C Dave P Dingal; Dennis E Discher
Crawling from soft to stiff matrix polarizes the cytoskeleton and phosphoregulates myosin-II heavy chain.
The Journal of cell biology 2012;199(4):669-83.
2012: Jae-Won Shin; Dennis E Discher
Cell culture: Soft gels select tumorigenic cells.
Nature materials 2012;11(8):662-3.
2012: Sharon M Loverde; Michael L Klein; Dennis E Discher
Nanoparticle shape improves delivery: rational coarse grain molecular dynamics (rCG-MD) of taxol in worm-like PEG-PCL micelles.
Advanced materials (Deerfield Beach, Fla.) 2012;24(28):3823-30.
2012: Nisha Sosale; Dennis E Discher
Marker-of-self becomes marker-of-senescence.
Blood 2012;119(23):5343-4.
2012: Florian Rehfeldt; Allison L Zajac; Assaf Zemel; André E X Brown; Shenshen Cai; Matthew Raab; Dennis E Discher
Hyaluronic acid matrices show matrix stiffness in 2D and 3D dictates cytoskeletal order and myosin-II phosphorylation within stem cells.
Integrative biology : quantitative biosciences from nano to macro 2012;4(4):422-30.
2012: Joe Swift; Dennis E Discher
Subcellular organization: change of phase in partitioning the cellular milieu.
Current biology : CB 2012;22(6):R188-90.
2011: Wouter G Ellenbroek; Paul A Janmey; David A Christian; Dennis E Discher; Yu-Hsiu Wang; Andrea J Liu
Divalent cation-dependent formation of electrostatic PIP2 clusters in lipid monolayers.
Biophysical journal 2011;101(9):2178-84.
2011: Vladimir V Shuvaev; Eric Simone; Sergei Zaitsev; Shenshen Cai; Dennis E Discher; Thomas D Dziubla; Marc A Ilies; Younghoon Kim; Abdullah Mahmud; Silvia Muro; Vladimir R Muzykantov
Endothelial targeting of antibody-decorated polymeric filomicelles.
ACS nano 2011;5(9):6991-9.
2011: Abdullah Mahmud; Dennis E Discher
Lung vascular targeting through inhalation delivery: insight from filamentous viruses and other shapes.
IUBMB life 2011;63(8):607-12.
2011: Jae-Won Shin; Kyle R Spinler; Joe Swift; Dennis E Discher
Myosin-II inhibition and soft 2D matrix maximize multinucleation and cellular projections typical of platelet-producing megakaryocytes.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(28):11458-63.
2011: Prashant K Purohit; Rustem I Litvinov; Andre E X Brown; Dennis E Discher; John W Weisel
Protein unfolding accounts for the unusual mechanical behavior of fibrin networks.
Acta biomaterialia 2011;7(6):2374-83.
2011: Christine C Krieger; Xiuli An; Hsin-Yao Tang; Narla Mohandas; David W Speicher; Dennis E Discher
Cysteine shotgun-mass spectrometry (CS-MS) reveals dynamic sequence of protein structure changes within mutant and stressed cells.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(20):8269-74.
2011: Diego A Pantano; Michael L Klein; Dennis E Discher; Preston B Moore
Morphologies of charged diblock copolymers simulated with a neutral coarse-grained model.
The journal of physical chemistry. B 2011;115(16):4689-95.
2011: Takamasa Harada; Dennis E Discher
Materials science: Bubble wrap of cell-like aggregates.
Nature 2011;471(7337):172-3.
2011: Shamik Sen; Manorama Tewari; Allison Zajac; Elisabeth R Barton; H Lee Sweeney; Dennis E Discher
Upregulation of paxillin and focal adhesion signaling follows Dystroglycan Complex deletions and promotes a hypertensive state of differentiation.
European journal of cell biology 2011;90(2-3):249-60.
2010: Christine Carag Krieger; Nishant Bhasin; Manorama Tewari; Andre E X Brown; Daniel Safer; H Lee Sweeney; Dennis E Discher
Exon-skipped dystrophins for treatment of Duchenne muscular dystrophy: mass spectrometry mapping of most exons and cooperative domain designs based on single molecule mechanics.
Cytoskeleton (Hoboken, N.J.) 2010;67(12):796-807.
2010: Amnon Buxboim; Dennis E Discher
Stem cells feel the difference.
Nature methods 2010;7(9):695-7.
2010: Richard K Tsai; Pia L Rodriguez; Dennis E Discher
Self inhibition of phagocytosis: the affinity of 'marker of self' CD47 for SIRPalpha dictates potency of inhibition but only at low expression levels.
Blood cells, molecules & diseases 2010;45(1):67-74.
2010: Amnon Buxboim; Karthikan Rajagopal; Andre' E X Brown; Dennis E Discher
How deeply cells feel: methods for thin gels.
Journal of physics. Condensed matter : an Institute of Physics journal 2010;22(19):194116.
2010: Amnon Buxboim; Irena L Ivanovska; Dennis E Discher
Matrix elasticity, cytoskeletal forces and physics of the nucleus: how deeply do cells 'feel' outside and in?
Journal of cell science 2010;123(Pt 3):297-308.
2010: David A Christian; Olga B Garbuzenko; Tamara Minko; Dennis E Discher
Polymer Vesicles with a Red Cell-like Surface Charge: Microvascular Imaging and in vivo Tracking with Near-Infrared Fluorescence.
Macromolecular rapid communications 2010;31(2):135-41.
2010: Matthew Raab; Jae-Won Shin; Dennis E Discher
Matrix elasticity in vitro controls muscle stem cell fate in vivo.
Stem cell research & therapy 2010;1(5):38.
2010: Tathagata Chaudhuri; Florian Rehfeldt; H Lee Sweeney; Dennis E Discher
Preparation of collagen-coated gels that maximize in vitro myogenesis of stem cells by matching the lateral elasticity of in vivo muscle.
Methods in molecular biology (Clifton, N.J.) 2010;621():185-202.
2009: David A Christian; Aiwei Tian; Wouter G Ellenbroek; Ilya Levental; Karthikan Rajagopal; Paul A Janmey; Andrea J Liu; Tobias Baumgart; Dennis E Discher
Spotted vesicles, striped micelles and Janus assemblies induced by ligand binding.
Nature materials 2009;8(10):843-9.
2009: Rebeca M Tenney; Dennis E Discher
Stem cells, microenvironment mechanics, and growth factor activation.
Current opinion in cell biology 2009;21(5):630-5.
2009: André E X Brown; Dennis E Discher
Conformational changes and signaling in cell and matrix physics.
Current biology : CB 2009;19(17):R781-9.
2009: Ilya Levental; David A Christian; Yu-Hsiu Wang; Jonathan J Madara; Dennis E Discher; Paul A Janmey
Calcium-dependent lateral organization in phosphatidylinositol 4,5-bisphosphate (PIP2)- and cholesterol-containing monolayers.
Biochemistry 2009;48(34):8241-8.
2009: David A Christian; Shenshen Cai; Olga B Garbuzenko; Takamasa Harada; Allison L Zajac; Tamara Minko; Dennis E Discher
Flexible filaments for in vivo imaging and delivery: persistent circulation of filomicelles opens the dosage window for sustained tumor shrinkage.
Molecular pharmaceutics 2009;6(5):1343-52.
2009: André E X Brown; Rustem I Litvinov; Dennis E Discher; Prashant K Purohit; John W Weisel
Multiscale mechanics of fibrin polymer: gel stretching with protein unfolding and loss of water.
Science (New York, N.Y.) 2009;325(5941):741-4.
2009: Dennis E Discher; David J Mooney; Peter W Zandstra
Growth factors, matrices, and forces combine and control stem cells.
Science (New York, N.Y.) 2009;324(5935):1673-7.
2009: Eric Simone; Thomas D Dziubla; Dennis E Discher; Vladimir R Muzykantov
Filamentous polymer nanocarriers of tunable stiffness that encapsulate the therapeutic enzyme catalase.
Biomacromolecules 2009;10(6):1324-30.
2009: André E X Brown; Alina Hategan; Daniel Safer; Yale E Goldman; Dennis E Discher
Cross-correlated TIRF/AFM reveals asymmetric distribution of force-generating heads along self-assembled, "synthetic" myosin filaments.
Biophysical journal 2009;96(5):1952-60.
2009: Younghoon Kim; Manorama Tewari; J David Pajerowski; Shenshen Cai; Shamik Sen; Jason H Williams; Jason Williams; Shashank R Sirsi; Shashank Sirsi; Gordon J Lutz; Gordon Lutz; Dennis E Discher
Polymersome delivery of siRNA and antisense oligonucleotides.
Journal of controlled release : official journal of the Controlled Release Society 2009;134(2):132-40.
2009: David A Christian; Shenshen Cai; Diana M Bowen; Younghoon Kim; J David Pajerowski; Dennis E Discher
Polymersome carriers: from self-assembly to siRNA and protein therapeutics.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2009;71(3):463-74.
2009: Dennis E Discher
The Foldome in cellular force transduction.
Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference 2009;2009():3341-2.
2008: Allison L Zajac; Dennis E Discher
Cell differentiation through tissue elasticity-coupled, myosin-driven remodeling.
Current opinion in cell biology 2008;20(6):609-15.
2008: Adam J Engler; Christine Carag-Krieger; Colin P Johnson; Matthew Raab; Hsin-Yao Tang; David W Speicher; Joseph W Sanger; Jean M Sanger; Dennis E Discher
Embryonic cardiomyocytes beat best on a matrix with heart-like elasticity: scar-like rigidity inhibits beating.
Journal of cell science 2008;121(Pt 22):3794-802.
2008: Richard K Tsai; Dennis E Discher
Inhibition of "self" engulfment through deactivation of myosin-II at the phagocytic synapse between human cells.
The Journal of cell biology 2008;180(5):989-1003.
2008: R Tsai; P Rodriguez; Dennis E Discher
Cys shotgun labeling of macrophages adhering to and engulfing Ig-opsonized cells.
Transfusion clinique et biologique : journal de la Société française de transfusion sanguine 2008;15(1-2):58-61.
2008: Rebecca G Wells; Dennis E Discher
Matrix elasticity, cytoskeletal tension, and TGF-beta: the insoluble and soluble meet.
Science signaling 2008;1(10):pe13.
2007: Eric Simone; Thomas D Dziubla; Francheska Colon-Gonzalez; Dennis E Discher; Vladimir R Muzykantov
Effect of polymer amphiphilicity on loading of a therapeutic enzyme into protective filamentous and spherical polymer nanocarriers.
Biomacromolecules 2007;8(12):3914-21.
2007: Florian Rehfeldt; Adam J Engler; Adam Eckhardt; Fariyal Ahmed; Dennis E Discher
Cell responses to the mechanochemical microenvironment--implications for regenerative medicine and drug delivery.
Advanced drug delivery reviews 2007;59(13):1329-39.
2007: Shenshen Cai; Kandaswamy Vijayan; Debbie Cheng; Eliana Lima; Dennis E Discher
Micelles of different morphologies--advantages of worm-like filomicelles of PEO-PCL in paclitaxel delivery.
Pharmaceutical research 2007;24(11):2099-109.
2007: J David Pajerowski; Kris Noel Dahl; Franklin L Zhong; Paul J Sammak; Dennis E Discher
Physical plasticity of the nucleus in stem cell differentiation.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(40):15619-24.
2007: Catherine PICART; Dennis E Discher
Materials science: embedded shells decalcified.
Nature 2007;448(7156):879-80.
2007: Colin P Johnson; Hsin-Yao Tang; Christine Carag; David W Speicher; Dennis E Discher
Forced unfolding of proteins within cells.
Science (New York, N.Y.) 2007;317(5838):663-6.
2007: Colin P Johnson; Massimiliano Gaetani; Vanessa Ortiz; Nishant Bhasin; Sandy Harper; Patrick G Gallagher; David W Speicher; Dennis E Discher
Pathogenic proline mutation in the linker between spectrin repeats: disease caused by spectrin unfolding.
Blood 2007;109(8):3538-43.
2007: Yan Geng; Paul Dalhaimer; Shenshen Cai; Richard Tsai; Manorama Tewari; Tamara Minko; Dennis E Discher
Shape effects of filaments versus spherical particles in flow and drug delivery.
Nature nanotechnology 2007;2(4):249-55.
2007: André E X Brown; Rustem I Litvinov; Dennis E Discher; John W Weisel
Forced unfolding of coiled-coils in fibrinogen by single-molecule AFM.
Biophysical journal 2007;92(5):L39-41.
2007: Shyamsundar Subramanian; Eric T Boder; Dennis E Discher
Phylogenetic divergence of CD47 interactions with human signal regulatory protein alpha reveals locus of species specificity. Implications for the binding site.
The Journal of biological chemistry 2007;282(3):1805-18.
2007: Adam J Engler; Florian Rehfeldt; Shamik Sen; Dennis E Discher
Microtissue elasticity: measurements by atomic force microscopy and its influence on cell differentiation.
Methods in cell biology 2007;83():521-45.
2007: Jan Lammerding; Kris Noel Dahl; Dennis E Discher; Roger Kamm
Nuclear mechanics and methods.
Methods in cell biology 2007;83():269-94.
2007: Margo T Frey; Adam J Engler; Dennis E Discher; Juliet Lee; Yu-Li Wang
Microscopic methods for measuring the elasticity of gel substrates for cell culture: microspheres, microindenters, and atomic force microscopy.
Methods in cell biology 2007;83():47-65.
2006: Fariyal Ahmed; Refika I Pakunlu; Aaron Brannan; Frank S Bates; Tamara Minko; Dennis E Discher
Biodegradable polymersomes loaded with both paclitaxel and doxorubicin permeate and shrink tumors, inducing apoptosis in proportion to accumulated drug.
Journal of controlled release : official journal of the Controlled Release Society 2006;116(2):150-8.
2006: Yan Geng; Dennis E Discher; Justyna Justynska; Helmut Schlaad
Grafting short peptides onto polybutadiene-block-poly(ethylene oxide): a platform for self-assembling hybrid amphiphiles.
Angewandte Chemie (International ed. in English) 2006;45(45):7578-81.
2006: Adam J Engler; Shamik Sen; H Lee Sweeney; Dennis E Discher
Matrix elasticity directs stem cell lineage specification.
Cell 2006;126(4):677-89.
2006: Amy G Brown; Rita S Leite; Adam J Engler; Dennis E Discher; Jerome F Strauss
A hemoglobin fragment found in cervicovaginal fluid from women in labor potentiates the action of agents that promote contraction of smooth muscle cells.
Peptides 2006;27(7):1794-800.
2006: Mark F Berry; Adam J Engler; Y Joseph Woo; Timothy J Pirolli; Lawrence T Bish; Vasant Jayasankar; Kevin J Morine; Timothy J Gardner; Dennis E Discher; H Lee Sweeney
Mesenchymal stem cell injection after myocardial infarction improves myocardial compliance.
American journal of physiology. Heart and circulatory physiology 2006;290(6):H2196-203.
2006: Dennis E Discher; Nishant Bhasin; Colin P Johnson
Covalent chemistry on distended proteins.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(20):7533-4.
2006: Fariyal Ahmed; Refika I Pakunlu; Goundla Srinivas; Aaron Brannan; Frank S Bates; Michael L Klein; Tamara Minko; Dennis E Discher
Shrinkage of a rapidly growing tumor by drug-loaded polymersomes: pH-triggered release through copolymer degradation.
Molecular pharmaceutics 2006;3(3):340-50.
2006: Shyamsundar Subramanian; Richard Tsai; Shamik Sen; Kris Noel Dahl; Dennis E Discher
Membrane mobility and clustering of Integrin Associated Protein (IAP, CD47)--major differences between mouse and man and implications for signaling.
Blood cells, molecules & diseases 2006;36(3):364-72.
2006: Shyamsundar Subramanian; Ranganath Parthasarathy; Shamik Sen; Eric T Boder; Dennis E Discher
Species- and cell type-specific interactions between CD47 and human SIRPalpha.
Blood 2006;107(6):2548-56.
2006: Kandaswamy Vijayan; Yan Geng; Dennis E Discher
Electric field manipulation of charged copolymer worm micelles.
The journal of physical chemistry. B 2006;110(8):3831-4.
2006: Shyamsundar Subramanian; R Tsai; Dennis E Discher
The 'metabolon,' CD47, and the 'phagocytic synapse': molecular co-localization and species divergence.
Transfusion clinique et biologique : journal de la Société française de transfusion sanguine 2006;13(1-2):31-8.
2006: Ranganath Parthasarathy; Shyamsundar Subramanian; Eric T Boder; Dennis E Discher
Post-translational regulation of expression and conformation of an immunoglobulin domain in yeast surface display.
Biotechnology and bioengineering 2006;93(1):159-68.
2006: Dennis E Discher; Fariyal Ahmed
Polymersomes.
Annual review of biomedical engineering 2006;8():323-41.
2005: Goundla Srinivas; Dennis E Discher; Michael L Klein
Key roles for chain flexibility in block copolymer membranes that contain pores or make tubes.
Nano letters 2005;5(12):2343-9.
2005: Dennis E Discher; Paul A Janmey; Yu-Li Wang
Tissue cells feel and respond to the stiffness of their substrate.
Science (New York, N.Y.) 2005;310(5751):1139-43.
2005: Shamik Sen; Shyamsundar Subramanian; Dennis E Discher
Indentation and adhesive probing of a cell membrane with AFM: theoretical model and experiments.
Biophysical journal 2005;89(5):3203-13.
2005: Kris Noel Dahl; Adam J Engler; J David Pajerowski; Dennis E Discher
Power-law rheology of isolated nuclei with deformation mapping of nuclear substructures.
Biophysical journal 2005;89(4):2855-64.
2005: Nishant Bhasin; Richard Law; George Liao; Daniel Safer; Jennifer Ellmer; Bohdana M Discher; H Lee Sweeney; Dennis E Discher
Molecular extensibility of mini-dystrophins and a dystrophin rod construct.
Journal of molecular biology 2005;352(4):795-806.
2005: Vanessa Ortiz; Steven O Nielsen; Dennis E Discher; Michael L Klein; Reinhard Lipowsky; Julian Shillcock
Dissipative particle dynamics simulations of polymersomes.
The journal of physical chemistry. B 2005;109(37):17708-14.
2005: Yan Geng; Dennis E Discher
Hydrolytic degradation of poly(ethylene oxide)-block-polycaprolactone worm micelles.
Journal of the American Chemical Society 2005;127(37):12780-1.
2005: Kandaswamy Vijayan; Dennis E Discher; Jyotsana Lal; Paul A Janmey; Mark Goulian
Interactions of membrane-active peptides with thick, neutral, nonzwitterionic bilayers.
The journal of physical chemistry. B 2005;109(30):14356-64.
2005: Younghoon Kim; David A Christian; Paul Dalhaimer; Dennis E Discher
Polymeric worm micelles as nano-carriers for drug delivery.
Nanotechnology 2005;16(7):S484-91.
2005: Vanessa Ortiz; Steven O Nielsen; Michael L Klein; Dennis E Discher
Unfolding a linker between helical repeats.
Journal of molecular biology 2005;349(3):638-47.
2005: Maureen A Griffin; Huisheng Feng; Manorama Tewari; Pedro Acosta; Masataka Kawana; H Lee Sweeney; Dennis E Discher
gamma-Sarcoglycan deficiency increases cell contractility, apoptosis and MAPK pathway activation but does not affect adhesion.
Journal of cell science 2005;118(Pt 7):1405-16.
2005: Yan Geng; Fariyal Ahmed; Nishant Bhasin; Dennis E Discher
Visualizing worm micelle dynamics and phase transitions of a charged diblock copolymer in water.
The journal of physical chemistry. B 2005;109(9):3772-9.
2004: Maureen A Griffin; Shamik Sen; H Lee Sweeney; Dennis E Discher
Adhesion-contractile balance in myocyte differentiation.
Journal of cell science 2004;117(Pt 24):5855-63.
2004: Alina Hategan; Kheya Sengupta; Samuel Kahn; Erich Sackmann; Dennis E Discher
Topographical pattern dynamics in passive adhesion of cell membranes.
Biophysical journal 2004;87(5):3547-60.
2004: Nishant Bhasin; Philippe Carl; Sandy Harper; Gang Feng; Hui Lu; David W Speicher; Dennis E Discher
Chemistry on a single protein, vascular cell adhesion molecule-1, during forced unfolding.
The Journal of biological chemistry 2004;279(44):45865-74.
2004: Paul A Janmey; Dennis E Discher
Developmental biology: holding it together in the eye.
Nature 2004;431(7009):635-6.
2004: Kris Noel Dahl; Samuel M Kahn; Katherine L Wilson; Dennis E Discher
The nuclear envelope lamina network has elasticity and a compressibility limit suggestive of a molecular shock absorber.
Journal of cell science 2004;117(Pt 20):4779-86.
2004: Adam J Engler; Maureen A Griffin; Shamik Sen; Carsten G Bönnemann; H Lee Sweeney; Dennis E Discher
Myotubes differentiate optimally on substrates with tissue-like stiffness: pathological implications for soft or stiff microenvironments.
The Journal of cell biology 2004;166(6):877-87.
2004: ludovic Richert; Adam J Engler; Dennis E Discher; Catherine PICART
Elasticity of native and cross-linked polyelectrolyte multilayer films.
Biomacromolecules 2004;5(5):1908-16.
2004: Paul Dalhaimer; Adam J Engler; Ranganath Parthasarathy; Dennis E Discher
Targeted worm micelles.
Biomacromolecules 2004;5(5):1714-9.
2004: Goundla Srinivas; Dennis E Discher; Michael L Klein
Self-assembly and properties of diblock copolymers by coarse-grain molecular dynamics.
Nature materials 2004;3(9):638-44.
2004: Dennis E Discher; Randall D Kamien
Self-assembly: towards precision micelles.
Nature 2004;430(6999):519-20.
2004: Veena Pata; Fariyal Ahmed; Dennis E Discher; Nily Dant
Membrane solubilization by detergent: resistance conferred by thickness.
Langmuir : the ACS journal of surfaces and colloids 2004;20(10):3888-93.
2004: Fariyal Ahmed; Dennis E Discher
Self-porating polymersomes of PEG-PLA and PEG-PCL: hydrolysis-triggered controlled release vesicles.
Journal of controlled release : official journal of the Controlled Release Society 2004;96(1):37-53.
2004: Richard Law; Sandy Harper; David W Speicher; Dennis E Discher
Influence of lateral association on forced unfolding of antiparallel spectrin heterodimers.
The Journal of biological chemistry 2004;279(16):16410-6.
2004: Z Dogic; Jinshan Zhang; A W C Lau; Helim Aranda-Espinoza; Paul Dalhaimer; Dennis E Discher; Paul A Janmey; Randall D Kamien; TC Lubensky; Arjun G Yodh
Elongation and fluctuations of semiflexible polymers in a nematic solvent.
Physical review letters 2004;92(12):125503.
2004: Maureen A Griffin; Adam J Engler; Thomas A Barber; Kevin healy; H Lee Sweeney; Dennis E Discher
Patterning, prestress, and peeling dynamics of myocytes.
Biophysical journal 2004;86(2):1209-22.
2004: Kris Noel Dahl; Ranganath Parthasarathy; Connie M Westhoff; D Mark Layton; Dennis E Discher
Protein 4.2 is critical to CD47-membrane skeleton attachment in human red cells.
Blood 2004;103(3):1131-6.
2004: Adam J Engler; Lucie Bacakova; Cynthia Newman; Alina Hategan; Maureen Griffin; Dennis E Discher
Substrate compliance versus ligand density in cell on gel responses.
Biophysical journal 2004;86(1 Pt 1):617-28.
2003: Richard Law; George Liao; Sandy Harper; Guoliang Yang; David W Speicher; Dennis E Discher
Pathway shifts and thermal softening in temperature-coupled forced unfolding of spectrin domains.
Biophysical journal 2003;85(5):3286-93.
2003: Alina Hategan; Richard Law; Samuel Kahn; Dennis E Discher
Adhesively-tensed cell membranes: lysis kinetics and atomic force microscopy probing.
Biophysical journal 2003;85(4):2746-59.
2003: Peter J Photos; Lucie Bacakova; Bohdana M Discher; Frank S Bates; Dennis E Discher
Polymer vesicles in vivo: correlations with PEG molecular weight.
Journal of controlled release : official journal of the Controlled Release Society 2003;90(3):323-34.
2003: Kris Noel Dahl; Connie M Westhoff; Dennis E Discher
Fractional attachment of CD47 (IAP) to the erythrocyte cytoskeleton and visual colocalization with Rh protein complexes.
Blood 2003;101(3):1194-9.
2003: Frédéric Tessier; David H Boal; Dennis E Discher
Networks with fourfold connectivity in two dimensions.
Physical review. E, Statistical, nonlinear, and soft matter physics 2003;67(1 Pt 1):011903.
2003: Richard Law; Philippe Carl; Sandy Harper; Paul Dalhaimer; David W Speicher; Dennis E Discher
Cooperativity in forced unfolding of tandem spectrin repeats.
Biophysical journal 2003;84(1):533-44.
2002: Helim Aranda-Espinoza; Philippe Carl; Jean-Francois Leterrier; Paul A Janmey; Dennis E Discher
Domain unfolding in neurofilament sidearms: effects of phosphorylation and ATP.
FEBS letters 2002;531(3):397-401.
2002: Dennis E Discher; Adi Eisenberg
Polymer vesicles.
Science (New York, N.Y.) 2002;297(5583):967-73.
2001: James C-M Lee; Dennis E Discher
Deformation-enhanced fluctuations in the red cell skeleton with theoretical relations to elasticity, connectivity, and spectrin unfolding.
Biophysical journal 2001;81(6):3178-92.
2001: Helim Aranda-Espinoza; Harry Bermudez; Frank S Bates; Dennis E Discher
Electromechanical limits of polymersomes.
Physical review letters 2001;87(20):208301.
2001: James C-M Lee; Harry Bermudez; Bohdana M Discher; M A Sheehan; Y Y Won; Frank S Bates; Dennis E Discher
Preparation, stability, and in vitro performance of vesicles made with diblock copolymers.
Biotechnology and bioengineering 2001;73(2):135-45.
2001: Philippe Carl; C H Kwok; Gavin A Manderson; David W Speicher; Dennis E Discher
Forced unfolding modulated by disulfide bonds in the Ig domains of a cell adhesion molecule.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(4):1565-70.
2001: Dennis E Discher; Philippe Carl
New insights into red cell network structure, elasticity, and spectrin unfolding--a current review.
Cellular & molecular biology letters 2001;6(3):593-606.
2000: Catherine PICART; Paul Dalhaimer; Dennis E Discher
Actin protofilament orientation in deformation of the erythrocyte membrane skeleton.
Biophysical journal 2000;79(6):2987-3000.
2000: Dennis E Discher
New insights into erythrocyte membrane organization and microelasticity.
Current opinion in hematology 2000;7(2):117-22.
1999: Catherine PICART; Dennis E Discher
Actin protofilament orientation at the erythrocyte membrane.
Biophysical journal 1999;77(2):865-78.
1999: James C-M Lee; D T Wong; Dennis E Discher
Direct measures of large, anisotropic strains in deformation of the erythrocyte cytoskeleton.
Biophysical journal 1999;77(2):853-64.
1999: Bohdana M Discher; Y Y Won; D S Ege; James C-M Lee; Frank S Bates; Dennis E Discher; Daniel A Hammer
Polymersomes: tough vesicles made from diblock copolymers.
Science (New York, N.Y.) 1999;284(5417):1143-6.
1999: H J Ra; Catherine PICART; H Feng; H Lee Sweeney; Dennis E Discher
Muscle cell peeling from micropatterned collagen: direct probing of focal and molecular properties of matrix adhesion.
Journal of cell science 1999;112 ( Pt 10)():1425-36.
1998: Dennis E Discher; David H Boal; S K Boey
Simulations of the erythrocyte cytoskeleton at large deformation. II. Micropipette aspiration.
Biophysical journal 1998;75(3):1584-97.
1998: S K Boey; David H Boal; Dennis E Discher
Simulations of the erythrocyte cytoskeleton at large deformation. I. Microscopic models.
Biophysical journal 1998;75(3):1573-83.
1996: Dennis E Discher; N Mohandas
Kinematics of red cell aspiration by fluorescence-imaged microdeformation.
Biophysical journal 1996;71(4):1680-94.