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Vishva Dixit

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Amino Acid Sequence

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Co-Publications
Name
19
O'Rourke, K
17
Chinnaiyan, Arul
16
Nickoloff, Brian
15
Mitra, Raj
13
Yan, Minhong
12
Sarma, Vidya
11
Varani, James
10
Salvesen, Guy
10
O'Shea, Sue
9
Pandey, Akhilesh
8
Ni, J
8
Fairbrother, Wayne
7
Vincenz, Claudius
7
Wertz, Ingrid
7
Grewal, Iqbal

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Publications

TOP 3
Vucic Domagoj; Dixit Vishva M
Masking MALT1: the paracaspase's potential for cancer therapy.
Lamkanfi Mohamed; Mueller James L; Vitari Alberto C; Misaghi Shahram; Fedorova Anna; Deshayes Kurt; Lee Wyne P; Hoffman Hal M; Dixit Vishva M
Glyburide inhibits the Cryopyrin/Nalp3 inflammasome.
Lamkanfi Mohamed; Dixit Vishva M
IL-33 raises alarm.

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All Publications

2009: Vucic Domagoj; Dixit Vishva M
Masking MALT1: the paracaspase's potential for cancer therapy.
The Journal of experimental medicine 2009;206(11):2309-12.
2009: Lamkanfi Mohamed; Mueller James L; Vitari Alberto C; Misaghi Shahram; Fedorova Anna; Deshayes Kurt; Lee Wyne P; Hoffman Hal M; Dixit Vishva M
Glyburide inhibits the Cryopyrin/Nalp3 inflammasome.
The Journal of cell biology 2009;187(1):61-70.
2009: Lamkanfi Mohamed; Dixit Vishva M
IL-33 raises alarm.
Immunity 2009;31(1):5-7.
2009: Misaghi Shahram; Ottosen Søren; Izrael-Tomasevic Anita; Arnott David; Lamkanfi Mohamed; Lee James; Liu Jinfeng; O'Rourke Karen; Dixit Vishva M; Wilson Angus C
Association of C-terminal ubiquitin hydrolase BRCA1-associated protein 1 with cell cycle regulator host cell factor 1.
Molecular and cellular biology 2009;29(8):2181-92.
2009: Kirkpatrick Donald S; Dixit Vishva M
GPS navigation of the protein-stability landscape.
Nature biotechnology 2009;27(1):46-8.
2009: Lamkanfi Mohamed; Dixit Vishva M
Inflammasomes: guardians of cytosolic sanctity.
Immunological reviews 2009;227(1):95-105.
2009: Kaufmann Thomas; Jost Philipp J; Pellegrini Marc; Puthalakath Hamsa; Gugasyan Raffi; Gerondakis Steve; Cretney Erika; Smyth Mark J; Silke John; Hakem Razq; Bouillet Philippe; Mak Tak W; Dixit Vishva M; Strasser Andreas
Fatal hepatitis mediated by tumor necrosis factor TNFalpha requires caspase-8 and involves the BH3-only proteins Bid and Bim.
Immunity 2009;30(1):56-66.
2008: Newton Kim; Matsumoto Marissa L; Wertz Ingrid E; Kirkpatrick Donald S; Lill Jennie R; Tan Jenille; Dugger Debra; Gordon Nathaniel; Sidhu Sachdev S; Fellouse Frederic A; Komuves Laszlo; French Dorothy M; Ferrando Ronald E; Lam Cynthia; Compaan Deanne; Yu Christine; Bosanac Ivan; Hymowitz Sarah G; Kelley Robert F; Dixit Vishva M
Ubiquitin chain editing revealed by polyubiquitin linkage-specific antibodies.
Cell 2008;134(4):668-78.
2008: Wertz Ingrid E; Dixit Vishva M
Ubiquitin-mediated regulation of TNFR1 signaling.
Cytokine & growth factor reviews 2008;19(3-4):313-24.
2008: Hsu Li-Chung; Ali Syed R; McGillivray Shauna; Tseng Ping-Hui; Mariathasan Sanjeev; Humke Eric W; Eckmann Lars; Powell Jonathan J; Nizet Victor; Dixit Vishva M; Karin Michael
A NOD2-NALP1 complex mediates caspase-1-dependent IL-1beta secretion in response to Bacillus anthracis infection and muramyl dipeptide.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(22):7803-8.
2007: Kayagaki Nobuhiko; Phung Qui; Chan Salina; Chaudhari Ruchir; Quan Casey; O'Rourke Karen M; Eby Michael; Pietras Eric; Cheng Genhong; Bazan J Fernando; Zhang Zemin; Arnott David; Dixit Vishva M
DUBA: a deubiquitinase that regulates type I interferon production.
Science (New York, N.Y.) 2007;318(5856):1628-32.
2007: Varfolomeev Eugene; Blankenship John W; Wayson Sarah M; Fedorova Anna V; Kayagaki Nobuhiko; Garg Parie; Zobel Kerry; Dynek Jasmin N; Elliott Linda O; Wallweber Heidi J A; Flygare John A; Fairbrother Wayne J; Deshayes Kurt; Dixit Vishva M; Vucic Domagoj
IAP antagonists induce autoubiquitination of c-IAPs, NF-kappaB activation, and TNFalpha-dependent apoptosis.
Cell 2007;131(4):669-81.
2007: Kaufmann Thomas; Tai Lin; Ekert Paul G; Huang David C S; Norris Fiona; Lindemann Ralph K; Johnstone Ricky W; Dixit Vishva M; Strasser Andreas
The BH3-only protein bid is dispensable for DNA damage- and replicative stress-induced apoptosis or cell-cycle arrest.
Cell 2007;129(2):423-33.
2007: Mollah Sahana; Wertz Ingrid E; Phung Qui; Arnott David; Dixit Vishva M; Lill Jennie R
Targeted mass spectrometric strategy for global mapping of ubiquitination on proteins.
Rapid communications in mass spectrometry : RCM 2007;21(20):3357-64.
2006: Varfolomeev Eugene; Wayson Sarah M; Dixit Vishva M; Fairbrother Wayne J; Vucic Domagoj
The inhibitor of apoptosis protein fusion c-IAP2.MALT1 stimulates NF-kappaB activation independently of TRAF1 AND TRAF2.
The Journal of biological chemistry 2006;281(39):29022-9.
2006: Dornan David; Shimizu Harumi; Mah Angie; Dudhela Tanay; Eby Michael; O'rourke Karen; Seshagiri Somasekar; Dixit Vishva M
ATM engages autodegradation of the E3 ubiquitin ligase COP1 after DNA damage.
Science (New York, N.Y.) 2006;313(5790):1122-6.
2006: Zamboni Dario S; Kobayashi Koichi S; Kohlsdorf Tiana; Ogura Yasunori; Long E Michelle; Vance Russell E; Kuida Keisuke; Mariathasan Sanjeev; Dixit Vishva M; Flavell Richard A; Dietrich William F; Roy Craig R
The Birc1e cytosolic pattern-recognition receptor contributes to the detection and control of Legionella pneumophila infection.
Nature immunology 2006;7(3):318-25.
2006: Mariathasan Sanjeev; Weiss David S; Newton Kim; McBride Jacqueline; O'Rourke Karen; Roose-Girma Meron; Lee Wyne P; Weinrauch Yvette; Monack Denise M; Dixit Vishva M
Cryopyrin activates the inflammasome in response to toxins and ATP.
Nature 2006;440(7081):228-32.
2005: Zhou Honglin; Monack Denise M; Kayagaki Nobuhiko; Wertz Ingrid; Yin Jianpin; Wolf Beni; Dixit Vishva M
Yersinia virulence factor YopJ acts as a deubiquitinase to inhibit NF-kappa B activation.
The Journal of experimental medicine 2005;202(10):1327-32.
2005: Mariathasan Sanjeev; Weiss David S; Dixit Vishva M; Monack Denise M
Innate immunity against Francisella tularensis is dependent on the ASC/caspase-1 axis.
The Journal of experimental medicine 2005;202(8):1043-9.
2005: Andersen Parker L; Zhou Honglin; Pastushok Landon; Moraes Trevor; McKenna Sean; Ziola Barry; Ellison Michael J; Dixit Vishva M; Xiao Wei
Distinct regulation of Ubc13 functions by the two ubiquitin-conjugating enzyme variants Mms2 and Uev1A.
The Journal of cell biology 2005;170(5):745-55.
2005: Martin Flavius; Dixit Vishva M
Unraveling TACIt functions.
Nature genetics 2005;37(8):793-4.
2005: Zhou Honglin; Du Ming-Qing; Dixit Vishva M
Constitutive NF-kappaB activation by the t(11;18)(q21;q21) product in MALT lymphoma is linked to deregulated ubiquitin ligase activity.
Cancer cell 2005;7(5):425-31.
2004: Dornan David; Bheddah Sheila; Newton Kim; Ince William; Frantz Gretchen D; Dowd Patrick; Koeppen Hartmut; Dixit Vishva M; French Dorothy M
COP1, the negative regulator of p53, is overexpressed in breast and ovarian adenocarcinomas.
Cancer research 2004;64(20):7226-30.
2004: Wertz Ingrid E; O'Rourke Karen M; Zhou Honglin; Eby Michael; Aravind L; Seshagiri Somasekar; Wu Ping; Wiesmann Christian; Baker Rohan; Boone David L; Ma Averil; Koonin Eugene V; Dixit Vishva M
De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signalling.
Nature 2004;430(7000):694-9.
2004: Mariathasan Sanjeev; Newton Kim; Monack Denise M; Vucic Domagoj; French Dorothy M; Lee Wyne P; Roose-Girma Meron; Erickson Sharon; Dixit Vishva M
Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf.
Nature 2004;430(6996):213-8.
2004: Dornan David; Wertz Ingrid; Shimizu Harumi; Arnott David; Frantz Gretchen D; Dowd Patrick; O'Rourke Karen; Koeppen Hartmut; Dixit Vishva M
The ubiquitin ligase COP1 is a critical negative regulator of p53.
Nature 2004;429(6987):86-92.
2004: Che Tuanjie; You Yun; Wang Donghai; Tanner Matthew J; Dixit Vishva M; Lin Xin
MALT1/paracaspase is a signaling component downstream of CARMA1 and mediates T cell receptor-induced NF-kappaB activation.
The Journal of biological chemistry 2004;279(16):15870-6.
2004: Newton Kim; French Dorothy M; Yan Minhong; Frantz Gretchen D; Dixit Vishva M
Myodegeneration in EDA-A2 transgenic mice is prevented by XEDAR deficiency.
Molecular and cellular biology 2004;24(4):1608-13.
2004: Newton Kim; Sun Xiaoqing; Dixit Vishva M
Kinase RIP3 is dispensable for normal NF-kappa Bs, signaling by the B-cell and T-cell receptors, tumor necrosis factor receptor 1, and Toll-like receptors 2 and 4.
Molecular and cellular biology 2004;24(4):1464-9.
2004: Wertz Ingrid E; O'Rourke Karen M; Zhang Zemin; Dornan David; Arnott David; Deshaies Raymond J; Dixit Vishva M
Human De-etiolated-1 regulates c-Jun by assembling a CUL4A ubiquitin ligase.
Science (New York, N.Y.) 2004;303(5662):1371-4.
2004: Zhou Honglin; Wertz Ingrid; O'Rourke Karen; Ultsch Mark; Seshagiri Somasekar; Eby Michael; Xiao Wei; Dixit Vishva M
Bcl10 activates the NF-kappaB pathway through ubiquitination of NEMO.
Nature 2004;427(6970):167-71.
2004: Ruefli-Brasse Astrid A; Lee Wyne P; Hurst Stephen; Dixit Vishva M
Rip2 participates in Bcl10 signaling and T-cell receptor-mediated NF-kappaB activation.
The Journal of biological chemistry 2004;279(2):1570-4.
2003: Hymowitz Sarah G; Compaan Deanne M; Yan Minhong; Wallweber Heidi J A; Dixit Vishva M; Starovasnik Melissa A; de Vos Abraham M
The crystal structures of EDA-A1 and EDA-A2: splice variants with distinct receptor specificity.
Structure (London, England : 1993) 2003;11(12):1513-20.
2003: Ruefli-Brasse Astrid A; French Dorothy M; Dixit Vishva M
Regulation of NF-kappaB-dependent lymphocyte activation and development by paracaspase.
Science (New York, N.Y.) 2003;302(5650):1581-4.
2003: Newton Kim; Dixit Vishva M
Mice lacking the CARD of CARMA1 exhibit defective B lymphocyte development and impaired proliferation of their B and T lymphocytes.
Current biology : CB 2003;13(14):1247-51.
2003: Gordon Nathaniel C; Pan Borlan; Hymowitz Sarah G; Yin JianPing; Kelley Robert F; Cochran Andrea G; Yan Minhong; Dixit Vishva M; Fairbrother Wayne J; Starovasnik Melissa A
BAFF/BLyS receptor 3 comprises a minimal TNF receptor-like module that encodes a highly focused ligand-binding site.
Biochemistry 2003;42(20):5977-83.
2003: Seshasayee Dhaya; Valdez Patricia; Yan Minhong; Dixit Vishva M; Tumas Daniel; Grewal Iqbal S
Loss of TACI causes fatal lymphoproliferation and autoimmunity, establishing TACI as an inhibitory BLyS receptor.
Immunity 2003;18(2):279-88.
2002: Kayagaki Nobuhiko; Yan Minhong; Seshasayee Dhaya; Wang Hua; Lee Wyne; French Dorothy M; Grewal Iqbal S; Cochran Andrea G; Gordon Nathaniel C; Yin JianPing; Starovasnik Melissa A; Dixit Vishva M
BAFF/BLyS receptor 3 binds the B cell survival factor BAFF ligand through a discrete surface loop and promotes processing of NF-kappaB2.
Immunity 2002;17(4):515-24.
2002: Vucic Domagoj; Deshayes Kurt; Ackerly Heidi; Pisabarro Maria Teresa; Kadkhodayan Saloumeh; Fairbrother Wayne J; Dixit Vishva M
SMAC negatively regulates the anti-apoptotic activity of melanoma inhibitor of apoptosis (ML-IAP).
The Journal of biological chemistry 2002;277(14):12275-9.
2002: Yan Minhong; Zhang Zemin; Brady John Ridgway; Schilbach Sarah; Fairbrother Wayne J; Dixit Vishva M
Identification of a novel death domain-containing adaptor molecule for ectodysplasin-A receptor that is mutated in crinkled mice.
Current biology : CB 2002;12(5):409-13.
2002: Sun Xiaoqing; Yin Jianping; Starovasnik Melissa A; Fairbrother Wayne J; Dixit Vishva M
Identification of a novel homotypic interaction motif required for the phosphorylation of receptor-interacting protein (RIP) by RIP3.
The Journal of biological chemistry 2002;277(11):9505-11.
2001: Zhao H; Yan M; Wang H; Erickson S; Grewal I S; Dixit V M
Impaired c-Jun amino terminal kinase activity and T cell differentiation in death receptor 6-deficient mice.
The Journal of experimental medicine 2001;194(10):1441-8.
2001: Yan M; Brady J R; Chan B; Lee W P; Hsu B; Harless S; Cancro M; Grewal I S; Dixit V M
Identification of a novel receptor for B lymphocyte stimulator that is mutated in a mouse strain with severe B cell deficiency.
Current biology : CB 2001;11(19):1547-52.
2001: Fairbrother W J; Gordon N C; Humke E W; O'Rourke K M; Starovasnik M A; Yin J P; Dixit V M
The PYRIN domain: a member of the death domain-fold superfamily.
Protein science : a publication of the Protein Society 2001;10(9):1911-8.
2001: Yan M; Wang H; Chan B; Roose-Girma M; Erickson S; Baker T; Tumas D; Grewal I S; Dixit V M
Activation and accumulation of B cells in TACI-deficient mice.
Nature immunology 2001;2(7):638-43.
2001: Wang H; Marsters S A; Baker T; Chan B; Lee W P; Fu L; Tumas D; Yan M; Dixit V M; Ashkenazi A; Grewal I S
TACI-ligand interactions are required for T cell activation and collagen-induced arthritis in mice.
Nature immunology 2001;2(7):632-7.
2000: Vucic D; Stennicke H R; Pisabarro M T; Salvesen G S; Dixit V M
ML-IAP, a novel inhibitor of apoptosis that is preferentially expressed in human melanomas.
Current biology : CB 2000;10(21):1359-66.
2000: Uren A G; O'Rourke K; Aravind L A; Pisabarro M T; Seshagiri S; Koonin E V; Dixit V M
Identification of paracaspases and metacaspases: two ancient families of caspase-like proteins, one of which plays a key role in MALT lymphoma.
Molecular cell 2000;6(4):961-7.
2000: Yan M; Wang L C; Hymowitz S G; Schilbach S; Lee J; Goddard A; de Vos A M; Gao W Q; Dixit V M
Two-amino acid molecular switch in an epithelial morphogen that regulates binding to two distinct receptors.
Science (New York, N.Y.) 2000;290(5491):523-7.
2000: Humke E W; Shriver S K; Starovasnik M A; Fairbrother W J; Dixit V M
ICEBERG: a novel inhibitor of interleukin-1beta generation.
Cell 2000;103(1):99-111.
2000: Yan M; Marsters S A; Grewal I S; Wang H; Ashkenazi A; Dixit V M
Identification of a receptor for BLyS demonstrates a crucial role in humoral immunity.
Nature immunology 2000;1(1):37-41.
2000: Marsters S A; Yan M; Pitti R M; Haas P E; Dixit V M; Ashkenazi A
Interaction of the TNF homologues BLyS and APRIL with the TNF receptor homologues BCMA and TACI.
Current biology : CB 2000;10(13):785-8.
2000: Wertz I E; Dixit V M
Characterization of calcium release-activated apoptosis of LNCaP prostate cancer cells.
The Journal of biological chemistry 2000;275(15):11470-7.
2000: Sosinowski T; Pandey A; Dixit V M; Weiss A
Src-like adaptor protein (SLAP) is a negative regulator of T cell receptor signaling.
The Journal of experimental medicine 2000;191(3):463-74.
1999: Seshagiri S; Vucic D; Lee J; Dixit V M
Baculovirus-based genetic screen for antiapoptotic genes identifies a novel IAP.
The Journal of biological chemistry 1999;274(51):36769-73.
1999: Salvesen G S; Dixit V M
Caspase activation: the induced-proximity model.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(20):10964-7.
1999: Sun X; Lee J; Navas T; Baldwin D T; Stewart T A; Dixit V M
RIP3, a novel apoptosis-inducing kinase.
The Journal of biological chemistry 1999;274(24):16871-5.
1999: Ashkenazi A; Dixit V M
Apoptosis control by death and decoy receptors.
Current opinion in cell biology 1999;11(2):255-60.
1999: Stennicke H R; Deveraux Q L; Humke E W; Reed J C; Dixit V M; Salvesen G S
Caspase-9 can be activated without proteolytic processing.
The Journal of biological chemistry 1999;274(13):8359-62.
1999: Song Q; Kuang Y; Dixit V M; Vincenz C
Boo, a novel negative regulator of cell death, interacts with Apaf-1.
The EMBO journal 1999;18(1):167-78.
1998: Hu S; Snipas S J; Vincenz C; Salvesen G; Dixit V M
Caspase-14 is a novel developmentally regulated protease.
The Journal of biological chemistry 1998;273(45):29648-53.
1998: McCarthy J V; Dixit V M
Apoptosis induced by Drosophila reaper and grim in a human system. Attenuation by inhibitor of apoptosis proteins (cIAPs).
The Journal of biological chemistry 1998;273(37):24009-15.
1998: Ashkenazi A; Dixit V M
Death receptors: signaling and modulation.
Science (New York, N.Y.) 1998;281(5381):1305-8.
1998: Pan G; Bauer J H; Haridas V; Wang S; Liu D; Yu G; Vincenz C; Aggarwal B B; Ni J; Dixit V M
Identification and functional characterization of DR6, a novel death domain-containing TNF receptor.
FEBS letters 1998;431(3):351-6.
1998: Chaudhary D; O'Rourke K; Chinnaiyan A M; Dixit V M
The death inhibitory molecules CED-9 and CED-4L use a common mechanism to inhibit the CED-3 death protease.
The Journal of biological chemistry 1998;273(28):17708-12.
1998: McCarthy J V; Ni J; Dixit V M
RIP2 is a novel NF-kappaB-activating and cell death-inducing kinase.
The Journal of biological chemistry 1998;273(27):16968-75.
1998: Humke E W; Ni J; Dixit V M
ERICE, a novel FLICE-activatable caspase.
The Journal of biological chemistry 1998;273(25):15702-7.
1998: Pan G; Humke E W; Dixit V M
Activation of caspases triggered by cytochrome c in vitro.
FEBS letters 1998;426(1):151-4.
1998: Pan G; Ni J; Yu G; Wei Y F; Dixit V M
TRUNDD, a new member of the TRAIL receptor family that antagonizes TRAIL signalling.
FEBS letters 1998;424(1-2):41-5.
1998: Pan G; O'Rourke K; Dixit V M
Caspase-9, Bcl-XL, and Apaf-1 form a ternary complex.
The Journal of biological chemistry 1998;273(10):5841-5.
1998: Muzio M; Stockwell B R; Stennicke H R; Salvesen G S; Dixit V M
An induced proximity model for caspase-8 activation.
The Journal of biological chemistry 1998;273(5):2926-30.
1997: Salvesen G S; Dixit V M
Caspases: intracellular signaling by proteolysis.
Cell 1997;91(4):443-6.
1997: Muzio M; Ni J; Feng P; Dixit V M
IRAK (Pelle) family member IRAK-2 and MyD88 as proximal mediators of IL-1 signaling.
Science (New York, N.Y.) 1997;278(5343):1612-5.
1997: Rehemtulla A; Hamilton C A; Chinnaiyan A M; Dixit V M
Ultraviolet radiation-induced apoptosis is mediated by activation of CD-95 (Fas/APO-1).
The Journal of biological chemistry 1997;272(41):25783-6.
1997: Chinnaiyan A M; Chaudhary D; O'Rourke K; Koonin E V; Dixit V M
Role of CED-4 in the activation of CED-3.
Nature 1997;388(6644):728-9.
1997: Pan G; Ni J; Wei Y F; Yu G; Gentz R; Dixit V M
An antagonist decoy receptor and a death domain-containing receptor for TRAIL.
Science (New York, N.Y.) 1997;277(5327):815-8.
1997: Hu S; Vincenz C; Ni J; Gentz R; Dixit V M
I-FLICE, a novel inhibitor of tumor necrosis factor receptor-1- and CD-95-induced apoptosis.
The Journal of biological chemistry 1997;272(28):17255-7.
1997: Hu S; Vincenz C; Buller M; Dixit V M
A novel family of viral death effector domain-containing molecules that inhibit both CD-95- and tumor necrosis factor receptor-1-induced apoptosis.
The Journal of biological chemistry 1997;272(15):9621-4.
1997: Orth K; Dixit V M
Bik and Bak induce apoptosis downstream of CrmA but upstream of inhibitor of apoptosis.
The Journal of biological chemistry 1997;272(14):8841-4.
1997: Pan G; O'Rourke K; Chinnaiyan A M; Gentz R; Ebner R; Ni J; Dixit V M
The receptor for the cytotoxic ligand TRAIL.
Science (New York, N.Y.) 1997;276(5309):111-3.
1997: Zhou Q; Snipas S; Orth K; Muzio M; Dixit V M; Salvesen G S
Target protease specificity of the viral serpin CrmA. Analysis of five caspases.
The Journal of biological chemistry 1997;272(12):7797-800.
1997: Vincenz C; Dixit V M
Fas-associated death domain protein interleukin-1beta-converting enzyme 2 (FLICE2), an ICE/Ced-3 homologue, is proximally involved in CD95- and p55-mediated death signaling.
The Journal of biological chemistry 1997;272(10):6578-83.
1997: Chinnaiyan A M; Dixit V M
Portrait of an executioner: the molecular mechanism of FAS/APO-1-induced apoptosis.
Seminars in immunology 1997;9(1):69-76.
1997: Chinnaiyan A M; O'Rourke K; Lane B R; Dixit V M
Interaction of CED-4 with CED-3 and CED-9: a molecular framework for cell death.
Science (New York, N.Y.) 1997;275(5303):1122-6.
1997: Muzio M; Salvesen G S; Dixit V M
FLICE induced apoptosis in a cell-free system. Cleavage of caspase zymogens.
The Journal of biological chemistry 1997;272(5):2952-6.
1997: Duan H; Dixit V M
RAIDD is a new 'death' adaptor molecule.
Nature 1997;385(6611):86-9.
1996: Singleton J R; Dixit V M; Feldman E L
Type I insulin-like growth factor receptor activation regulates apoptotic proteins.
The Journal of biological chemistry 1996;271(50):31791-4.
1996: Cahill M A; Peter M E; Kischkel F C; Chinnaiyan A M; Dixit V M; Krammer P H; Nordheim A
CD95 (APO-1/Fas) induces activation of SAP kinases downstream of ICE-like proteases.
Oncogene 1996;13(10):2087-96.
1996: Froelich C J; Orth K; Turbov J; Seth P; Gottlieb R; Babior B; Shah G M; Bleackley R C; Dixit V M; Hanna W
New paradigm for lymphocyte granule-mediated cytotoxicity. Target cells bind and internalize granzyme B, but an endosomolytic agent is necessary for cytosolic delivery and subsequent apoptosis.
The Journal of biological chemistry 1996;271(46):29073-9.
1996: Chinnaiyan A M; O'Rourke K; Yu G L; Lyons R H; Garg M; Duan D R; Xing L; Gentz R; Ni J; Dixit V M
Signal transduction by DR3, a death domain-containing receptor related to TNFR-1 and CD95.
Science (New York, N.Y.) 1996;274(5289):990-2.
1996: Orth K; O'Rourke K; Salvesen G S; Dixit V M
Molecular ordering of apoptotic mammalian CED-3/ICE-like proteases.
The Journal of biological chemistry 1996;271(35):20977-80.
1996: Vincenz C; Dixit V M
14-3-3 proteins associate with A20 in an isoform-specific manner and function both as chaperone and adapter molecules.
The Journal of biological chemistry 1996;271(33):20029-34.
1996: Chinnaiyan A M; Hanna W L; Orth K; Duan H; Poirier G G; Froelich C J; Dixit V M
Cytotoxic T-cell-derived granzyme B activates the apoptotic protease ICE-LAP3.
Current biology : CB 1996;6(7):897-9.
1996: Orth K; Chinnaiyan A M; Garg M; Froelich C J; Dixit V M
The CED-3/ICE-like protease Mch2 is activated during apoptosis and cleaves the death substrate lamin A.
The Journal of biological chemistry 1996;271(28):16443-6.
1996: Duan H; Orth K; Chinnaiyan A M; Poirier G G; Froelich C J; He W W; Dixit V M
ICE-LAP6, a novel member of the ICE/Ced-3 gene family, is activated by the cytotoxic T cell protease granzyme B.
The Journal of biological chemistry 1996;271(28):16720-4.
1996: Muzio M; Chinnaiyan A M; Kischkel F C; O'Rourke K; Shevchenko A; Ni J; Scaffidi C; Bretz J D; Zhang M; Gentz R; Mann M; Krammer P H; Peter M E; Dixit V M
FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex.
Cell 1996;85(6):817-27.
1996: Chinnaiyan A M; Dixit V M
The cell-death machine.
Current biology : CB 1996;6(5):555-62.
1996: Pandey A; Liu X; Dixon J E; Di Fiore P P; Dixit V M
Direct association between the Ret receptor tyrosine kinase and the Src homology 2-containing adapter protein Grb7.
The Journal of biological chemistry 1996;271(18):10607-10.
1996: Chinnaiyan A M; Tepper C G; Seldin M F; O'Rourke K; Kischkel F C; Hellbardt S; Krammer P H; Peter M E; Dixit V M
FADD/MORT1 is a common mediator of CD95 (Fas/APO-1) and tumor necrosis factor receptor-induced apoptosis.
The Journal of biological chemistry 1996;271(9):4961-5.
1996: Chinnaiyan A M; Orth K; O'Rourke K; Duan H; Poirier G G; Dixit V M
Molecular ordering of the cell death pathway. Bcl-2 and Bcl-xL function upstream of the CED-3-like apoptotic proteases.
The Journal of biological chemistry 1996;271(9):4573-6.
1996: Tewari M; Dixit V M
Recent advances in tumor necrosis factor and CD40 signaling.
Current opinion in genetics & development 1996;6(1):39-44.
1996: Duan H; Chinnaiyan A M; Hudson P L; Wing J P; He W W; Dixit V M
ICE-LAP3, a novel mammalian homologue of the Caenorhabditis elegans cell death protein Ced-3 is activated during Fas- and tumor necrosis factor-induced apoptosis.
The Journal of biological chemistry 1996;271(3):1621-5.
1996: Dixit V M
Role of ICE-proteases in apoptosis.
Advances in experimental medicine and biology 1996;406():113-7.
1995: Varani J; Dame M K; Taylor C G; Sarma V; Merino R; Kunkel R G; Nunez G; Dixit V M
Age-dependent injury in human umbilical vein endothelial cells: relationship to apoptosis and correlation with a lack of A20 expression.
Laboratory investigation; a journal of technical methods and pathology 1995;73(6):851-8.
1995: Pandey A; Lindberg R A; Dixit V M
Cell signalling. Receptor orphans find a family.
Current biology : CB 1995;5(9):986-9.
1995: Pandey A; Duan H; Di Fiore P P; Dixit V M
The Ret receptor protein tyrosine kinase associates with the SH2-containing adapter protein Grb10.
The Journal of biological chemistry 1995;270(37):21461-3.
1995: Tewari M; Telford W G; Miller R A; Dixit V M
CrmA, a poxvirus-encoded serpin, inhibits cytotoxic T-lymphocyte-mediated apoptosis.
The Journal of biological chemistry 1995;270(39):22705-8.
1995: Pandey A; Duan H; Dixit V M
Characterization of a novel Src-like adapter protein that associates with the Eck receptor tyrosine kinase.
The Journal of biological chemistry 1995;270(33):19201-4.
1995: Tewari M; Beidler D R; Dixit V M
CrmA-inhibitable cleavage of the 70-kDa protein component of the U1 small nuclear ribonucleoprotein during Fas- and tumor necrosis factor-induced apoptosis.
The Journal of biological chemistry 1995;270(32):18738-41.
1995: Beidler D R; Tewari M; Friesen P D; Poirier G; Dixit V M
The baculovirus p35 protein inhibits Fas- and tumor necrosis factor-induced apoptosis.
The Journal of biological chemistry 1995;270(28):16526-8.
1995: Tewari M; Quan L T; O'Rourke K; Desnoyers S; Zeng Z; Beidler D R; Poirier G G; Salvesen G S; Dixit V M
Yama/CPP32 beta, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase.
Cell 1995;81(5):801-9.
1995: Sarma V; Lin Z; Clark L; Rust B M; Tewari M; Noelle R J; Dixit V M
Activation of the B-cell surface receptor CD40 induces A20, a novel zinc finger protein that inhibits apoptosis.
The Journal of biological chemistry 1995;270(21):12343-6.
1995: Chinnaiyan A M; O'Rourke K; Tewari M; Dixit V M
FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis.
Cell 1995;81(4):505-12.
1995: Pandey A; Shao H; Marks R M; Polverini P J; Dixit V M
Role of B61, the ligand for the Eck receptor tyrosine kinase, in TNF-alpha-induced angiogenesis.
Science (New York, N.Y.) 1995;268(5210):567-9.
1995: Shao H; Pandey A; O'Shea K S; Seldin M; Dixit V M
Characterization of B61, the ligand for the Eck receptor protein-tyrosine kinase.
The Journal of biological chemistry 1995;270(10):5636-41.
1995: Shao H; Lou L; Pandey A; Verderame M F; Siever D A; Dixit V M
cDNA cloning and characterization of a Cek7 receptor protein-tyrosine kinase ligand that is identical to the ligand (ELF-1) for the Mek-4 and Sek receptor protein-tyrosine kinases.
The Journal of biological chemistry 1995;270(8):3467-70.
1995: Tewari M; Wolf F W; Seldin M F; O'Shea K S; Dixit V M; Turka L A
Lymphoid expression and regulation of A20, an inhibitor of programmed cell death.
Journal of immunology (Baltimore, Md. : 1950) 1995;154(4):1699-706.
1995: Tewari M; Dixit V M
Fas- and tumor necrosis factor-induced apoptosis is inhibited by the poxvirus crmA gene product.
The Journal of biological chemistry 1995;270(7):3255-60.
1994: Pandey A; Lazar D F; Saltiel A R; Dixit V M
Activation of the Eck receptor protein tyrosine kinase stimulates phosphatidylinositol 3-kinase activity.
The Journal of biological chemistry 1994;269(48):30154-7.
1994: Hu H M; O'Rourke K; Boguski M S; Dixit V M
A novel RING finger protein interacts with the cytoplasmic domain of CD40.
The Journal of biological chemistry 1994;269(48):30069-72.
1994: Shao H; Lou L; Pandey A; Pasquale E B; Dixit V M
cDNA cloning and characterization of a ligand for the Cek5 receptor protein-tyrosine kinase.
The Journal of biological chemistry 1994;269(43):26606-9.
1994: Nickoloff B J; Mitra R S; Varani J; Dixit V M; Polverini P J
Aberrant production of interleukin-8 and thrombospondin-1 by psoriatic keratinocytes mediates angiogenesis.
The American journal of pathology 1994;144(4):820-8.
1994: Hoffman J R; Dixit V M; O'Shea K S
Expression of thrombospondin in the adult nervous system.
The Journal of comparative neurology 1994;340(1):126-39.
1994: Wolf F W; Sarma V; Seldin M; Drake S; Suchard S J; Shao H; O'Shea K S; Dixit V M
B94, a primary response gene inducible by tumor necrosis factor-alpha, is expressed in developing hematopoietic tissues and the sperm acrosome.
The Journal of biological chemistry 1994;269(5):3633-40.
1994: Qabar A N; Lin Z; Wolf F W; O'Shea K S; Lawler J; Dixit V M
Thrombospondin 3 is a developmentally regulated heparin binding protein.
The Journal of biological chemistry 1994;269(2):1262-9.
1994: Suchard S J; Mansfield P J; Dixit V M
Modulation of thrombospondin receptor expression during HL-60 cell differentiation.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(2):877-88.
1993: Yabkowitz R; Dixit V M; Guo N; Roberts D D; Shimizu Y
Activated T-cell adhesion to thrombospondin is mediated by the alpha 4 beta 1 (VLA-4) and alpha 5 beta 1 (VLA-5) integrins.
Journal of immunology (Baltimore, Md. : 1950) 1993;151(1):149-58.
1993: Laherty C D; Perkins N D; Dixit V M
Human T cell leukemia virus type I Tax and phorbol 12-myristate 13-acetate induce expression of the A20 zinc finger protein by distinct mechanisms involving nuclear factor kappa B.
The Journal of biological chemistry 1993;268(7):5032-9.
1993: Castle V P; Ou X; O'Rourke K; Dixit V M
High level thrombospondin 1 expression in two NIH 3T3 cloned lines confers serum- and anchorage-independent growth.
The Journal of biological chemistry 1993;268(4):2899-903.
1993: Yabkowitz R; Mansfield P J; Dixit V M; Suchard S J
Motility of human carcinoma cells in response to thrombospondin: relationship to metastatic potential and thrombospondin structural domains.
Cancer research 1993;53(2):378-87.
1992: O'Rourke K M; Laherty C D; Dixit V M
Thrombospondin 1 and thrombospondin 2 are expressed as both homo- and heterotrimers.
The Journal of biological chemistry 1992;267(35):24921-4.
1992: Laherty C D; Hu H M; Opipari A W; Wang F; Dixit V M
The Epstein-Barr virus LMP1 gene product induces A20 zinc finger protein expression by activating nuclear factor kappa B.
The Journal of biological chemistry 1992;267(34):24157-60.
1992: Castle V P; Ou X; O'Shea S; Dixit V M
Induction of thrombospondin 1 by retinoic acid is important during differentiation of neuroblastoma cells.
The Journal of clinical investigation 1992;90(5):1857-63.
1992: Krikos A; Laherty C D; Dixit V M
Transcriptional activation of the tumor necrosis factor alpha-inducible zinc finger protein, A20, is mediated by kappa B elements.
The Journal of biological chemistry 1992;267(25):17971-6.
1992: Opipari A W; Hu H M; Yabkowitz R; Dixit V M
The A20 zinc finger protein protects cells from tumor necrosis factor cytotoxicity.
The Journal of biological chemistry 1992;267(18):12424-7.
1992: Sarma V; Wolf F W; Marks R M; Shows T B; Dixit V M
Cloning of a novel tumor necrosis factor-alpha-inducible primary response gene that is differentially expressed in development and capillary tube-like formation in vitro.
Journal of immunology (Baltimore, Md. : 1950) 1992;148(10):3302-12.
1992: Dixit V M
Thrombospondin and tumor necrosis factor.
Kidney international 1992;41(3):679-82.
1992: Laherty C D; O'Rourke K; Wolf F W; Katz R; Seldin M F; Dixit V M
Characterization of mouse thrombospondin 2 sequence and expression during cell growth and development.
The Journal of biological chemistry 1992;267(5):3274-81.
1992: Wolf F W; Marks R M; Sarma V; Byers M G; Katz R W; Shows T B; Dixit V M
Characterization of a novel tumor necrosis factor-alpha-induced endothelial primary response gene.
The Journal of biological chemistry 1992;267(2):1317-26.
1992: Stoof T J; Mitra R S; Sarma V; Dixit V M; Nickoloff B J
Keratinocyte activation following T-lymphocyte binding.
The Journal of investigative dermatology 1992;98(1):92-5.
1991: Barker J N; Jones M L; Mitra R S; Crockett-Torabe E; Fantone J C; Kunkel S L; Warren J S; Dixit V M; Nickoloff B J
Modulation of keratinocyte-derived interleukin-8 which is chemotactic for neutrophils and T lymphocytes.
The American journal of pathology 1991;139(4):869-76.
1991: O'Shea K S; Liu L H; Dixit V M
Thrombospondin and a 140 kd fragment promote adhesion and neurite outgrowth from embryonic central and peripheral neurons and from PC12 cells.
Neuron 1991;7(2):231-7.
1991: Suchard S J; Boxer L A; Dixit V M
Activation of human neutrophils increases thrombospondin receptor expression.
Journal of immunology (Baltimore, Md. : 1950) 1991;147(2):651-9.
1991: Yabkowitz R; Dixit V M
Human carcinoma cells bind thrombospondin through a Mr 80,000/105,000 receptor.
Cancer research 1991;51(14):3648-56.
1991: Suchard S J; Burton M J; Dixit V M; Boxer L A
Human neutrophil adherence to thrombospondin occurs through a CD11/CD18-independent mechanism.
Journal of immunology (Baltimore, Md. : 1950) 1991;146(11):3945-52.
1991: Barker J N; Karabin G D; Stoof T J; Sarma V J; Dixit V M; Nickoloff B J
Detection of interferon-gamma mRNA in psoriatic epidermis by polymerase chain reaction.
Journal of dermatological science 1991;2(2):106-11.
1991: Yabkowitz R; Dixit V M
Human carcinoma cells express receptors for distinct domains of thrombospondin.
Cancer research 1991;51(6):1645-50.
1991: Barker J N; Jones M L; Swenson C L; Sarma V; Mitra R S; Ward P A; Johnson K J; Fantone J C; Dixit V M; Nickoloff B J
Monocyte chemotaxis and activating factor production by keratinocytes in response to IFN-gamma.
Journal of immunology (Baltimore, Md. : 1950) 1991;146(4):1192-7.
1991: Nickoloff B J; Karabin G D; Barker J N; Griffiths C E; Sarma V; Mitra R S; Elder J T; Kunkel S L; Dixit V M
Cellular localization of interleukin-8 and its inducer, tumor necrosis factor-alpha in psoriasis.
The American journal of pathology 1991;138(1):129-40.
1991: Barker J N; Mitra R S; Griffiths C E; Dixit V M; Nickoloff B J
Keratinocytes as initiators of inflammation.
Lancet 1991;337(8735):211-4.
1990: O'Shea K S; Liu L H; Kinnunen L H; Dixit V M
Role of the extracellular matrix protein thrombospondin in the early development of the mouse embryo.
The Journal of cell biology 1990;111(6 Pt 1):2713-23.
1990: Holzman L B; Marks R M; Dixit V M
A novel immediate-early response gene of endothelium is induced by cytokines and encodes a secreted protein.
Molecular and cellular biology 1990;10(11):5830-8.
1990: Opipari A W; Boguski M S; Dixit V M
The A20 cDNA induced by tumor necrosis factor alpha encodes a novel type of zinc finger protein.
The Journal of biological chemistry 1990;265(25):14705-8.
1990: Long M W; Dixit V M
Thrombospondin functions as a cytoadhesion molecule for human hematopoietic progenitor cells.
Blood 1990;75(12):2311-8.
1990: Varani J; Mitra R S; Gibbs D; Phan S H; Dixit V M; Mitra R; Wang T; Siebert K J; Nickoloff B J; Voorhees J J
All-trans retinoic acid stimulates growth and extracellular matrix production in growth-inhibited cultured human skin fibroblasts.
The Journal of investigative dermatology 1990;94(5):717-23.
1990: Wolf F W; Eddy R L; Shows T B; Dixit V M
Structure and chromosomal localization of the human thrombospondin gene.
Genomics 1990;6(4):685-91.
1990: O'Shea K S; Rheinheimer J S; Dixit V M
Deposition and role of thrombospondin in the histogenesis of the cerebellar cortex.
The Journal of cell biology 1990;110(4):1275-83.
1990: Dixit V M; Green S; Sarma V; Holzman L B; Wolf F W; O'Rourke K; Ward P A; Prochownik E V; Marks R M
Tumor necrosis factor-alpha induction of novel gene products in human endothelial cells including a macrophage-specific chemotaxin.
The Journal of biological chemistry 1990;265(5):2973-8.
1990: Barker J N; Sarma V; Mitra R S; Dixit V M; Nickoloff B J
Marked synergism between tumor necrosis factor-alpha and interferon-gamma in regulation of keratinocyte-derived adhesion molecules and chemotactic factors.
The Journal of clinical investigation 1990;85(2):605-8.
1990: Riser B L; Varani J; Nickoloff B J; Mitra R S; Dixit V M
Thrombospondin binding by keratinocytes: modulation under conditions which alter thrombospondin biosynthesis.
Dermatologica 1990;180(2):60-5.
1989: Dixit V M; Marks R M; Sarma V; Prochownik E V
The antimitogenic action of tumor necrosis factor is associated with increased AP-1/c-jun proto-oncogene transcription.
The Journal of biological chemistry 1989;264(28):16905-9.
1989: Varani J; Nickoloff B J; Dixit V M; Mitra R S; Voorhees J J
All-trans retinoic acid stimulates growth of adult human keratinocytes cultured in growth factor-deficient medium, inhibits production of thrombospondin and fibronectin, and reduces adhesion.
The Journal of investigative dermatology 1989;93(4):449-54.
1989: Prochownik E V; O'Rourke K; Dixit V M
Expression and analysis of COOH-terminal deletions of the human thrombospondin molecule.
The Journal of cell biology 1989;109(2):843-52.
1989: Phan S H; Dillon R G; McGarry B M; Dixit V M
Stimulation of fibroblast proliferation by thrombospondin.
Biochemical and biophysical research communications 1989;163(1):56-63.
1989: Laherty C D; Gierman T M; Dixit V M
Characterization of the promoter region of the human thrombospondin gene. DNA sequences within the first intron increase transcription.
The Journal of biological chemistry 1989;264(19):11222-7.
1989: Yabkowitz R; Lowe J B; Dixit V M
Expression and initial characterization of a recombinant human thrombospondin heparin binding domain.
The Journal of biological chemistry 1989;264(18):10888-96.
1989: Varani J; Mitra R S; McClenic B J; Fligiel S E; Inman D R; Dixit V M; Nickoloff B J
Modulation of fibronectin production in normal human melanocytes and malignant melanoma cells by interferon-gamma and tumor necrosis factor-alpha.
The American journal of pathology 1989;134(4):827-36.
1989: McClenic B K; Mitra R S; Riser B L; Nickoloff B J; Dixit V M; Varani J
Production and utilization of extracellular matrix components by human melanocytes.
Experimental cell research 1989;180(2):314-25.
1988: O'Shea K S; Dixit V M
Unique distribution of the extracellular matrix component thrombospondin in the developing mouse embryo.
The Journal of cell biology 1988;107(6 Pt 2):2737-48.
1988: Nickoloff B J; Mitra R S; Riser B L; Dixit V M; Varani J
Modulation of keratinocyte motility. Correlation with production of extracellular matrix molecules in response to growth promoting and antiproliferative factors.
The American journal of pathology 1988;132(3):543-51.
1988: Nickoloff B J; Riser B L; Mitra R S; Dixit V M; Varani J
Inhibitory effect of gamma interferon on cultured human keratinocyte thrombospondin production, distribution, and biologic activities.
The Journal of investigative dermatology 1988;91(3):213-8.
1988: Varani J; Nickoloff B J; Riser B L; Mitra R S; O'Rourke K; Dixit V M
Thrombospondin-induced adhesion of human keratinocytes.
The Journal of clinical investigation 1988;81(5):1537-44.
1988: Riser B L; Varani J; O'Rourke K; Dixit V M
Thrombospondin binding by human squamous carcinoma and melanoma cells: relationship to biological activity.
Experimental cell research 1988;174(2):319-29.

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