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Jack Dixon

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TOP 3
Vincent S Tagliabracci; Lorenzo A Pinna; Jack E Dixon
Secreted protein kinases.
Vincent S Tagliabracci; Jianzhong Wen; Sandra E Wiley; Carolyn A Worby; Junyu Xiao; James L Engel; Nick V Grishin; Lisa N Kinch; Jack E Dixon
Secreted kinase phosphorylates extracellular proteins that regulate biomineralization.
Xing Guo; Lan Huang; Vincent S Tagliabracci; Xiaorong Wang; Junyu Xiao; James L Engel; Jack E Dixon
UBLCP1 is a 26S proteasome phosphatase that regulates nuclear proteasome activity.

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All Publications

2013: Vincent S Tagliabracci; Lorenzo A Pinna; Jack E Dixon
Secreted protein kinases.
Trends in biochemical sciences 2013;38(3):121-30.
2012: Vincent S Tagliabracci; Jianzhong Wen; Sandra E Wiley; Carolyn A Worby; Junyu Xiao; James L Engel; Nick V Grishin; Lisa N Kinch; Jack E Dixon
Secreted kinase phosphorylates extracellular proteins that regulate biomineralization.
Science (New York, N.Y.) 2012;336(6085):1150-3.
2011: Xing Guo; Lan Huang; Vincent S Tagliabracci; Xiaorong Wang; Junyu Xiao; James L Engel; Jack E Dixon
UBLCP1 is a 26S proteasome phosphatase that regulates nuclear proteasome activity.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(46):18649-54.
2011: Seema Mattoo; Junyu Xiao; Mark J Chen; Jack E Dixon; Eric Durrant; Cheri S Lazar; Gerard Manning; Carolyn A Worby
Comparative analysis of Histophilus somni immunoglobulin-binding protein A (IbpA) with other fic domain-containing enzymes reveals differences in substrate and nucleotide specificities.
The Journal of biological chemistry 2011;286(37):32834-42.
2011: Junyu Xiao; Ji Zhang; Mark J Chen; James L Engel; Gerard Manning; Jack E Dixon
Structural and functional analysis of PTPMT1, a phosphatase required for cardiolipin synthesis.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(29):11860-5.
2011: Ji Zhang; Ziqiang Guan; Anne N Murphy; Sandra E Wiley; Guy A Perkins; Carolyn A Worby; James L Engel; Philip Heacock; Oanh Kim Nguyen; Jonathan H Wang; Christian R H Raetz; William Dowhan; Jack E Dixon
Mitochondrial phosphatase PTPMT1 is essential for cardiolipin biosynthesis.
Cell metabolism 2011;13(6):690-700.
2011: Carolyn A Worby; Jack E Dixon
Glycogen synthase: an old enzyme with a new trick.
Cell metabolism 2011;13(3):233-4.
2010: Junyu Xiao; Carolyn A Worby; Seema Mattoo; Banumathi Sankaran; Jack E Dixon
Structural basis of Fic-mediated adenylylation.
Nature structural & molecular biology 2010;17(8):1004-10.
2010: Mengmeng Zhang; June Liu; Youngjun Kim; Jack E Dixon; Samuel L Pfaff; Gordon N Gill; Joseph P Noel; Yan Zhang
Structural and functional analysis of the phosphoryl transfer reaction mediated by the human small C-terminal domain phosphatase, Scp1.
Protein science : a publication of the Protein Society 2010;19(5):974-86.
2009: Matthew J Rardin; Sandra E Wiley; Robert K Naviaux; Anne N Murphy; Jack E Dixon
Monitoring phosphorylation of the pyruvate dehydrogenase complex.
Analytical biochemistry 2009;389(2):157-64.
2009: Douglas A Mitchell; Shaun W Lee; Morgan A Pence; Andrew L Markley; Joyce D Limm; Victor Nizet; Jack E Dixon
Structural and functional dissection of the heterocyclic peptide cytotoxin streptolysin S.
The Journal of biological chemistry 2009;284(19):13004-12.
2009: Carolyn A Worby; Seema Mattoo; Robert P Kruger; Lynette B Corbeil; Antonius Koller; Juan C Mendez; Bereket Zekarias; Cheri Lazar; Jack E Dixon
The fic domain: regulation of cell signaling by adenylylation.
Molecular cell 2009;34(1):93-103.
2009: Matthew J Rardin; Gregory S Taylor; Jack E Dixon
Distinguishing mitochondrial inner membrane orientation of dual specific phosphatase 18 and 21.
Methods in enzymology 2009;457():275-87.
2009: Sandra E Wiley; Matthew J Rardin; Jack E Dixon
Chapter 13 Localization and function of the 2Fe-2S outer mitochondrial membrane protein mitoNEET.
Methods in enzymology 2009;456():233-46.
2008: Matthew J Rardin; Sandra E Wiley; Anne N Murphy; David J Pagliarini; Jack E Dixon
Dual specificity phosphatases 18 and 21 target to opposing sides of the mitochondrial inner membrane.
The Journal of biological chemistry 2008;283(22):15440-50.
2008: Shaun W Lee; Douglas Mitchell; Andrew L Markley; Mary E Hensler; David Gonzalez; Aaron Wohlrab; Pieter dorrestein; Victor Nizet; Jack E Dixon
Discovery of a widely distributed toxin biosynthetic gene cluster.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(15):5879-84.
2008: Fred L Robinson; Ingrid R Niesman; Kristina K Beiswenger; Jack E Dixon
Loss of the inactive myotubularin-related phosphatase Mtmr13 leads to a Charcot-Marie-Tooth 4B2-like peripheral neuropathy in mice.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(12):4916-21.
2008: Carolyn A Worby; Matthew S Gentry; Jack E Dixon
Malin decreases glycogen accumulation by promoting the degradation of protein targeting to glycogen (PTG).
The Journal of biological chemistry 2008;283(7):4069-76.
2007: Alan Cheng; Mei Zhang; Matthew S Gentry; Carolyn A Worby; Jack E Dixon; Alan Saltiel
A role for AGL ubiquitination in the glycogen storage disorders of Lafora and Cori's disease.
Genes & development 2007;21(19):2399-409.
2007: Neal M Alto; Andrew W Weflen; Matthew J Rardin; Defne Yarar; Cheri S Lazar; Raffi Tonikian; Antonius Koller; Susan S Taylor; Charles Boone; Sachdev S Sidhu; Sandra L Schmid; Gail Hecht; Jack E Dixon
The type III effector EspF coordinates membrane trafficking by the spatiotemporal activation of two eukaryotic signaling pathways.
The Journal of cell biology 2007;178(7):1265-78.
2007: Mark L Paddock; Sandra E Wiley; Herbert L Axelrod; Aina E Cohen; Melinda Roy; Edward C Abresch; Dominique Capraro; Anne N Murphy; Rachel Nechushtai; Jack E Dixon; Patricia Jennings
MitoNEET is a uniquely folded 2Fe 2S outer mitochondrial membrane protein stabilized by pioglitazone.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(36):14342-7.
2007: Sandra E Wiley; Mark L Paddock; Edward C Abresch; Larry Gross; Peter van der Geer; Rachel Nechushtai; Anne N Murphy; Patricia Jennings; Jack E Dixon
The outer mitochondrial membrane protein mitoNEET contains a novel redox-active 2Fe-2S cluster.
The Journal of biological chemistry 2007;282(33):23745-9.
2007: Matthew S Gentry; Robert H Dowen; Carolyn A Worby; Seema Mattoo; Joseph R Ecker; Jack E Dixon
The phosphatase laforin crosses evolutionary boundaries and links carbohydrate metabolism to neuronal disease.
The Journal of cell biology 2007;178(3):477-88.
2007: Lorena Navarro; Antonius Koller; Roland Nordfelth; Hans Wolf-Watz; Susan Taylor; Jack E Dixon
Identification of a molecular target for the Yersinia protein kinase A.
Molecular cell 2007;26(4):465-77.
2007: Sandra E Wiley; Anne N Murphy; Stuart A Ross; Peter van der Geer; Jack E Dixon
MitoNEET is an iron-containing outer mitochondrial membrane protein that regulates oxidative capacity.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(13):5318-23.
2006: Carolyn A Worby; Matthew S Gentry; Jack E Dixon
Laforin, a dual specificity phosphatase that dephosphorylates complex carbohydrates.
The Journal of biological chemistry 2006;281(41):30412-8.
2006: Fred L Robinson; Jack E Dixon
Myotubularin phosphatases: policing 3-phosphoinositides.
Trends in cell biology 2006;16(8):403-12.
2006: Carolyn A Worby; Jack E Dixon
Microbiology. Bacteria seize control by acetylating host proteins.
Science (New York, N.Y.) 2006;312(5777):1150-1.
2006: Michael J Begley; Gregory S Taylor; Melissa A Brock; Partho Ghosh; Virgil L Woods; Jack E Dixon
Molecular basis for substrate recognition by MTMR2, a myotubularin family phosphoinositide phosphatase.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(4):927-32.
2006: Neal M Alto; Feng Shao; Cheri S Lazar; Renée L Brost; Gordon Chua; Seema Mattoo; Stephen McMahon; Partho Ghosh; Timothy R Hughes; Charles Boone; Jack E Dixon
Identification of a bacterial type III effector family with G protein mimicry functions.
Cell 2006;124(1):133-45.
2006: Stephen J Juris; Kavita Shah; Kevan M Shokat; Jack E Dixon; Panayiotis O Vacratsis
Identification of otubain 1 as a novel substrate for the Yersinia protein kinase using chemical genetics and mass spectrometry.
FEBS letters 2006;580(1):179-83.
2006: Michelle T Paulsen; Adrienne M Starks; Frederick A Derheimer; Sheela Hanasoge; Liwu Li; Jack E Dixon; Mats Ljungman
The p53-targeting human phosphatase hCdc14A interacts with the Cdk1/cyclin B complex and is differentially expressed in human cancers.
Molecular cancer 2006;5():25.
2006: David J Pagliarini; Jack E Dixon
Mitochondrial modulation: reversible phosphorylation takes center stage?
Trends in biochemical sciences 2006;31(1):26-34.
2005: Michael J Begley; Jack E Dixon
The structure and regulation of myotubularin phosphatases.
Current opinion in structural biology 2005;15(6):614-20.
2005: Carolyn A Worby; Jack E Dixon
Phosphoinositide phosphatases: emerging roles as voltage sensors?
Molecular interventions 2005;5(5):274-7.
2005: Fred L Robinson; Jack E Dixon
The phosphoinositide-3-phosphatase MTMR2 associates with MTMR13, a membrane-associated pseudophosphatase also mutated in type 4B Charcot-Marie-Tooth disease.
The Journal of biological chemistry 2005;280(36):31699-707.
2005: David J Pagliarini; Sandra E Wiley; Michelle Kimple; Jesse R Dixon; Patrick Kelly; Carolyn A Worby; Patrick J Casey; Jack E Dixon
Involvement of a mitochondrial phosphatase in the regulation of ATP production and insulin secretion in pancreatic beta cells.
Molecular cell 2005;19(2):197-207.
2005: Matthew S Gentry; Carolyn A Worby; Jack E Dixon
Insights into Lafora disease: malin is an E3 ubiquitin ligase that ubiquitinates and promotes the degradation of laforin.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(24):8501-6.
2005: Lorena Navarro; Neal M Alto; Jack E Dixon
Functions of the Yersinia effector proteins in inhibiting host immune responses.
Current opinion in microbiology 2005;8(1):21-7.
2004: David J Pagliarini; Carolyn A Worby; Jack E Dixon
A PTEN-like phosphatase with a novel substrate specificity.
The Journal of biological chemistry 2004;279(37):38590-6.
2004: Tomohiko Maehama; Natsuki Kosaka; Fumiaki Okahara; Ken-ichi Takeuchi; Masato Umeda; Jack E Dixon; Yasunori Kanaho
Suppression of a phosphatidylinositol 3-kinase signal by a specific spliced variant of Drosophila PTEN.
FEBS letters 2004;565(1-3):43-7.
2004: Carolyn A Worby; Jack E Dixon
RNA interference in cultured Drosophila cells.
Current protocols in molecular biology / edited by Frederick M. Ausubel ... [et al.] 2004;Chapter 26():Unit 26.5.
2004: Minfeng Zhu; Feng Shao; Roger W Innes; Jack E Dixon; Zhaohui Xu
The crystal structure of Pseudomonas avirulence protein AvrPphB: a papain-like fold with a distinct substrate-binding site.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(1):302-7.
2004: Gregory S Taylor; Jack E Dixon
Assaying phosphoinositide phosphatases.
Methods in molecular biology (Clifton, N.J.) 2004;284():217-27.
2003: Michael J Begley; Gregory S Taylor; Soo-A Kim; Donna M Veine; Jack E Dixon; Jeanne A Stuckey
Crystal structure of a phosphoinositide phosphatase, MTMR2: insights into myotubular myopathy and Charcot-Marie-Tooth syndrome.
Molecular cell 2003;12(6):1391-402.
2003: Sylvain Merlot; ruedi meili; David J Pagliarini; Tomohiko Maehama; Jack E Dixon; Richard A Firtel
A PTEN-related 5-phosphatidylinositol phosphatase localized in the Golgi.
The Journal of biological chemistry 2003;278(41):39866-73.
2003: Feng Shao; Catherine Golstein; Jules Ade; Mark Stoutemyer; Jack E Dixon; Roger W Innes
Cleavage of Arabidopsis PBS1 by a bacterial type III effector.
Science (New York, N.Y.) 2003;301(5637):1230-3.
2003: Christine McDonald; Panayiotis O Vacratsis; James B Bliska; Jack E Dixon
The yersinia virulence factor YopM forms a novel protein complex with two cellular kinases.
The Journal of biological chemistry 2003;278(20):18514-23.
2003: Soo-A Kim; Panayiotis O Vacratsis; Ron Firestein; Michael L Cleary; Jack E Dixon
Regulation of myotubularin-related (MTMR)2 phosphatidylinositol phosphatase by MTMR5, a catalytically inactive phosphatase.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(8):4492-7.
2003: Feng Shao; Panayiotis O Vacratsis; Zhaoqin Bao; Katherine E Bowers; Carol A Fierke; Jack E Dixon
Biochemical characterization of the Yersinia YopT protease: cleavage site and recognition elements in Rho GTPases.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(3):904-9.
2003: Feng Shao; Jack E Dixon
YopT is a cysteine protease cleaving Rho family GTPases.
Advances in experimental medicine and biology 2003;529():79-84.
2002: Matthew J Wishart; Jack E Dixon
PTEN and myotubularin phosphatases: from 3-phosphoinositide dephosphorylation to disease.
Trends in cell biology 2002;12(12):579-85.
2002: Carolyn A Worby; Jack E Dixon
Sorting out the cellular functions of sorting nexins.
Nature reviews. Molecular cell biology 2002;3(12):919-31.
2002: Marco Muda; Carolyn A Worby; Nancy Simonson-Leff; James C Clemens; Jack E Dixon
Use of double-stranded RNA-mediated interference to determine the substrates of protein tyrosine kinases and phosphatases.
The Biochemical journal 2002;366(Pt 1):73-7.
2002: Feng Shao; Peter M Merritt; Zhaoqin Bao; Roger W Innes; Jack E Dixon
A Yersinia effector and a Pseudomonas avirulence protein define a family of cysteine proteases functioning in bacterial pathogenesis.
Cell 2002;109(5):575-88.
2002: Robert P Kruger; Harry C Winter; Nancy Simonson-Leff; Jeanne A Stuckey; Irwin J Goldstein; Jack E Dixon
Cloning, expression, and characterization of the Galalpha 1,3Gal high affinity lectin from the mushroom Marasmius oreades.
The Journal of biological chemistry 2002;277(17):15002-5.
2002: Stephen J Juris; Feng Shao; Jack E Dixon
Yersinia effectors target mammalian signalling pathways.
Cellular microbiology 2002;4(4):201-11.
2002: Carolyn A Worby; Nancy Simonson-Leff; James C Clemens; Donald Huddler; Marco Muda; Jack E Dixon
Drosophila Ack targets its substrate, the sorting nexin DSH3PX1, to a protein complex involved in axonal guidance.
The Journal of biological chemistry 2002;277(11):9422-8.
2002: Matthew J Wishart; Jack E Dixon
The archetype STYX/dead-phosphatase complexes with a spermatid mRNA-binding protein and is essential for normal sperm production.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(4):2112-7.
2002: Soo-A Kim; Gregory S Taylor; Knut M Torgersen; Jack E Dixon
Myotubularin and MTMR2, phosphatidylinositol 3-phosphatases mutated in myotubular myopathy and type 4B Charcot-Marie-Tooth disease.
The Journal of biological chemistry 2002;277(6):4526-31.
2002: Jianyong Wang; Jeanne A Stuckey; Matthew J Wishart; Jack E Dixon
A unique carbohydrate binding domain targets the lafora disease phosphatase to glycogen.
The Journal of biological chemistry 2002;277(4):2377-80.
2001: Carolyn A Worby; Nancy Simonson-Leff; James C Clemens; Robert P Kruger; Marco Muda; Jack E Dixon
The sorting nexin, DSH3PX1, connects the axonal guidance receptor, Dscam, to the actin cytoskeleton.
The Journal of biological chemistry 2001;276(45):41782-9.
2001: Carolyn A Worby; Nancy Simonson-Leff; Jack E Dixon
RNA interference of gene expression (RNAi) in cultured Drosophila cells.
Science's STKE : signal transduction knowledge environment 2001;2001(95):pl1.
2001: Gregory S Taylor; Jack E Dixon
An assay for phosphoinositide phosphatases utilizing fluorescent substrates.
Analytical biochemistry 2001;295(1):122-6.
2001: Matthew J Wishart; Gregory S Taylor; Jack E Dixon
Phoxy lipids: revealing PX domains as phosphoinositide binding modules.
Cell 2001;105(7):817-20.
2001: Matthew J Wishart; Gregory S Taylor; J T Slama; Jack E Dixon
PTEN and myotubularin phosphoinositide phosphatases: bringing bioinformatics to the lab bench.
Current opinion in cell biology 2001;13(2):172-81.
2001: T Maehama; Gregory S Taylor; Jack E Dixon
PTEN and myotubularin: novel phosphoinositide phosphatases.
Annual review of biochemistry 2001;70():247-79.
2000: Kim Orth; Zhaohui Xu; Mary Beth Mudgett; Zhao Qin Bao; Lance E Palmer; James B Bliska; W F Mangel; Brian J Staskawicz; Jack E Dixon
Disruption of signaling by Yersinia effector YopJ, a ubiquitin-like protein protease.
Science (New York, N.Y.) 2000;290(5496):1594-7.
2000: Tomohiko Maehama; Jack E Dixon
[PTEN tumor suppressor: functions as a lipid phosphatase].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 2000;45(14):2405-14.
2000: Stephen J Juris; AE Rudolph; Donald P Huddler; Kim Orth; Jack E Dixon
A distinctive role for the Yersinia protein kinase: actin binding, kinase activation, and cytoskeleton disruption.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(17):9431-6.
2000: Eric A Toth; Carolyn A Worby; Jack E Dixon; Eric R Goedken; Susan Marqusee; Todd O Yeates
The crystal structure of adenylosuccinate lyase from Pyrobaculum aerophilum reveals an intracellular protein with three disulfide bonds.
Journal of molecular biology 2000;301(2):433-50.
2000: Gregory S Taylor; T Maehama; Jack E Dixon
Myotubularin, a protein tyrosine phosphatase mutated in myotubular myopathy, dephosphorylates the lipid second messenger, phosphatidylinositol 3-phosphate.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(16):8910-5.
2000: Dietmar Schmucker; James C Clemens; H Shu; Carolyn A Worby; J Xiao; Marco Muda; Jack E Dixon; S Lawrence Zipursky
Drosophila Dscam is an axon guidance receptor exhibiting extraordinary molecular diversity.
Cell 2000;101(6):671-84.
2000: James C Clemens; Carolyn A Worby; Nancy Simonson-Leff; Marco Muda; T Maehama; B A Hemmings; Jack E Dixon
Use of double-stranded RNA interference in Drosophila cell lines to dissect signal transduction pathways.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(12):6499-503.
2000: T Maehama; Gregory S Taylor; J T Slama; Jack E Dixon
A sensitive assay for phosphoinositide phosphatases.
Analytical biochemistry 2000;279(2):248-50.
2000: Kathleen M Woods Ignatoski; T Maehama; Sonja M Markwart; Jack E Dixon; Donna L Livant; Stephen Ethier
ERBB-2 overexpression confers PI 3' kinase-dependent invasion capacity on human mammary epithelial cells.
British journal of cancer 2000;82(3):666-74.
1999: Kim Orth; Lance E Palmer; Zhao Qin Bao; Scott Stewart; AE Rudolph; James B Bliska; Jack E Dixon
Inhibition of the mitogen-activated protein kinase kinase superfamily by a Yersinia effector.
Science (New York, N.Y.) 1999;285(5435):1920-3.
1999: Marco Muda; E R Manning; Kim Orth; Jack E Dixon
Identification of the human YVH1 protein-tyrosine phosphatase orthologue reveals a novel zinc binding domain essential for in vivo function.
The Journal of biological chemistry 1999;274(34):23991-5.
1999: AE Rudolph; Jeanne A Stuckey; Yunde Zhao; H R Matthews; W A Patton; J Moss; Jack E Dixon
Expression, characterization, and mutagenesis of the Yersinia pestis murine toxin, a phospholipase D superfamily member.
The Journal of biological chemistry 1999;274(17):11824-31.
1999: T Maehama; Jack E Dixon
PTEN: a tumour suppressor that functions as a phospholipid phosphatase.
Trends in cell biology 1999;9(4):125-8.
1999: Jeanne A Stuckey; Jack E Dixon
Crystal structure of a phospholipase D family member.
Nature structural biology 1999;6(3):278-84.
1999: TT Lee; Carolyn A Worby; Zhao Qin Bao; Jack E Dixon; Roberta F Colman
His68 and His141 are critical contributors to the intersubunit catalytic site of adenylosuccinate lyase of Bacillus subtilis.
Biochemistry 1999;38(1):22-32.
1998: E B Gottlin; AE Rudolph; Yunde Zhao; H R Matthews; Jack E Dixon
Catalytic mechanism of the phospholipase D superfamily proceeds via a covalent phosphohistidine intermediate.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(16):9202-7.
1998: Matthew J Wishart; Jack E Dixon
Gathering STYX: phosphatase-like form predicts functions for unique protein-interaction domains.
Trends in biochemical sciences 1998;23(8):301-6.
1998: TT Lee; Carolyn A Worby; Zhao Qin Bao; Jack E Dixon; Roberta F Colman
Implication of His68 in the substrate site of Bacillus subtilis adenylosuccinate lyase by mutagenesis and affinity labeling with 2-[(4-bromo-2,3-dioxobutyl)thio]adenosine 5'-monophosphate.
Biochemistry 1998;37(23):8481-9.
1998: T Maehama; Jack E Dixon
The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate.
The Journal of biological chemistry 1998;273(22):13375-8.
1998: Carolyn A Worby; Q C Vega; H H Chao; Audrey F Seasholtz; Robert C Thompson; Jack E Dixon
Identification and characterization of GFRalpha-3, a novel Co-receptor belonging to the glial cell line-derived neurotrophic receptor family.
The Journal of biological chemistry 1998;273(6):3502-8.
1997: S Zhuo; Jack E Dixon
Effects of sulfhydryl regents on the activity of lambda Ser/Thr phosphoprotein phosphatase and inhibition of the enzyme by zinc ion.
Protein engineering 1997;10(12):1445-52.
1997: Y Zhao; Jeanne A Stuckey; D L Lohse; Jack E Dixon
Expression, characterization, and crystallization of a member of the novel phospholipase D family of phosphodiesterases.
Protein science : a publication of the Protein Society 1997;6(12):2655-8.
1997: Linheng Li; BR Ernsting; Matthew J Wishart; D L Lohse; Jack E Dixon
A family of putative tumor suppressors is structurally and functionally conserved in humans and yeast.
The Journal of biological chemistry 1997;272(47):29403-6.
1997: L R Fitzgerald; K M Walton; Jack E Dixon; B L Largent
PTP NE-6: a brain-enriched receptor-type protein tyrosine phosphatase with a divergent catalytic domain.
Journal of neurochemistry 1997;68(5):1820-9.
1997: D L Lohse; John M Denu; N Santoro; Jack E Dixon
Roles of aspartic acid-181 and serine-222 in intermediate formation and hydrolysis of the mammalian protein-tyrosine-phosphatase PTP1.
Biochemistry 1997;36(15):4568-75.
1997: BR Ernsting; Jack E Dixon
The PPS1 gene of Saccharomyces cerevisiae codes for a dual specificity protein phosphatase with a role in the DNA synthesis phase of the cell cycle.
The Journal of biological chemistry 1997;272(14):9332-43.
1997: TT Lee; Carolyn A Worby; Jack E Dixon; Roberta F Colman
Identification of His141 in the active site of Bacillus subtilis adenylosuccinate lyase by affinity labeling with 6-(4-bromo-2,3-dioxobutyl)thioadenosine 5'-monophosphate.
The Journal of biological chemistry 1997;272(1):458-65.
1996: A M Wiland; John M Denu; R J Mourey; Jack E Dixon
Purification and kinetic characterization of the mitogen-activated protein kinase phosphatase rVH6.
The Journal of biological chemistry 1996;271(52):33486-92.
1996: E B Gottlin; X Xu; D M Epstein; S P Burke; J W Eckstein; David P Ballou; Jack E Dixon
Kinetic analysis of the catalytic domain of human cdc25B.
The Journal of biological chemistry 1996;271(44):27445-9.
1996: John M Denu; Jeanne A Stuckey; Mark Saper; Jack E Dixon
Form and function in protein dephosphorylation.
Cell 1996;87(3):361-4.
1996: Q C Vega; C A Worby; M S Lechner; Jack E Dixon; Gregory R Dressler
Glial cell line-derived neurotrophic factor activates the receptor tyrosine kinase RET and promotes kidney morphogenesis.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(20):10657-61.
1996: C A Worby; Q C Vega; Yunde Zhao; H H Chao; Audrey F Seasholtz; Jack E Dixon
Glial cell line-derived neurotrophic factor signals through the RET receptor and activates mitogen-activated protein kinase.
The Journal of biological chemistry 1996;271(39):23619-22.
1996: James C Clemens; Z Ursuliak; K K Clemens; James V Price; Jack E Dixon
A Drosophila protein-tyrosine phosphatase associates with an adapter protein required for axonal guidance.
The Journal of biological chemistry 1996;271(29):17002-5.
1996: J Yuvaniyama; John M Denu; Jack E Dixon; Mark Saper
Crystal structure of the dual specificity protein phosphatase VHR.
Science (New York, N.Y.) 1996;272(5266):1328-31.
1996: Akhilesh Pandey; X Liu; Jack E Dixon; P P Di Fiore; Xiaodong Huang
Direct association between the Ret receptor tyrosine kinase and the Src homology 2-containing adapter protein Grb7.
The Journal of biological chemistry 1996;271(18):10607-10.
1996: M R Redinbo; S M Eide; R L Stone; Jack E Dixon; Todd O Yeates
Crystallization and preliminary structural analysis of Bacillus subtilis adenylosuccinate lyase, an enzyme implicated in infantile autism.
Protein science : a publication of the Protein Society 1996;5(4):786-8.
1996: John M Denu; D L Lohse; J Vijayalakshmi; Mark Saper; Jack E Dixon
Visualization of intermediate and transition-state structures in protein-tyrosine phosphatase catalysis.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(6):2493-8.
1996: X Liu; Q C Vega; R A Decker; Akhilesh Pandey; C A Worby; Jack E Dixon
Oncogenic RET receptors display different autophosphorylation sites and substrate binding specificities.
The Journal of biological chemistry 1996;271(10):5309-12.
1996: R J Mourey; Q C Vega; J S Campbell; M P Wenderoth; Stephen D Hauschka; Edwin G Krebs; Jack E Dixon
A novel cytoplasmic dual specificity protein tyrosine phosphatase implicated in muscle and neuronal differentiation.
The Journal of biological chemistry 1996;271(7):3795-802.
1996: X Wu; S J Noh; G Zhou; Jack E Dixon; K L Guan
Selective activation of MEK1 but not MEK2 by A-Raf from epidermal growth factor-stimulated Hela cells.
The Journal of biological chemistry 1996;271(6):3265-71.
1995: Matthew J Wishart; John M Denu; John Williams; Jack E Dixon
A single mutation converts a novel phosphotyrosine binding domain into a dual-specificity phosphatase.
The Journal of biological chemistry 1995;270(45):26782-5.
1995: D L Lohse; John M Denu; Jack E Dixon
Insights derived from the structures of the Ser/Thr phosphatases calcineurin and protein phosphatase 1.
Structure (London, England : 1993) 1995;3(10):987-90.
1995: K J Martell; Audrey F Seasholtz; S P Kwak; K K Clemens; Jack E Dixon
hVH-5: a protein tyrosine phosphatase abundant in brain that inactivates mitogen-activated protein kinase.
Journal of neurochemistry 1995;65(4):1823-33.
1995: H L Schubert; E B Fauman; Jeanne A Stuckey; Jack E Dixon; Mark Saper
A ligand-induced conformational change in the Yersinia protein tyrosine phosphatase.
Protein science : a publication of the Protein Society 1995;4(9):1904-13.
1995: John M Denu; Jack E Dixon
A catalytic mechanism for the dual-specific phosphatases.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(13):5910-4.
1995: G Zhou; Z Q Bao; Jack E Dixon
Components of a new human protein kinase signal transduction pathway.
The Journal of biological chemistry 1995;270(21):12665-9.
1995: John M Denu; G Zhou; Y Guo; Jack E Dixon
The catalytic role of aspartic acid-92 in a human dual-specific protein-tyrosine-phosphatase.
Biochemistry 1995;34(10):3396-403.
1995: John M Denu; G Zhou; L Wu; R Zhao; J Yuvaniyama; Mark Saper; Jack E Dixon
The purification and characterization of a human dual-specific protein tyrosine phosphatase.
The Journal of biological chemistry 1995;270(8):3796-803.
1995: S P Kwak; Jack E Dixon
Multiple dual specificity protein tyrosine phosphatases are expressed and regulated differentially in liver cell lines.
The Journal of biological chemistry 1995;270(3):1156-60.
1994: Zhong-Yin Zhang; Y Wang; L Wu; E B Fauman; Jeanne A Stuckey; H L Schubert; Mark Saper; Jack E Dixon
The Cys(X)5Arg catalytic motif in phosphoester hydrolysis.
Biochemistry 1994;33(51):15266-70.
1994: R L Stone; Jack E Dixon
Protein-tyrosine phosphatases.
The Journal of biological chemistry 1994;269(50):31323-6.
1994: Laura J Mauro; E A Olmsted; B M Skrobacz; R J Mourey; A R Davis; Jack E Dixon
Identification of a hormonally regulated protein tyrosine phosphatase associated with bone and testicular differentiation.
The Journal of biological chemistry 1994;269(48):30659-67.
1994: E G Ninfa; Jack E Dixon
Protein tyrosine phosphatases in disease processes.
Trends in cell biology 1994;4(12):427-30.
1994: G Zhou; John M Denu; L Wu; Jack E Dixon
The catalytic role of Cys124 in the dual specificity phosphatase VHR.
The Journal of biological chemistry 1994;269(45):28084-90.
1994: S Zhuo; James C Clemens; R L Stone; Jack E Dixon
Mutational analysis of a Ser/Thr phosphatase. Identification of residues important in phosphoesterase substrate binding and catalysis.
The Journal of biological chemistry 1994;269(42):26234-8.
1994: Jeanne A Stuckey; H L Schubert; E B Fauman; Zhong-Yin Zhang; Jack E Dixon; Mark Saper
Crystal structure of Yersinia protein tyrosine phosphatase at 2.5 A and the complex with tungstate.
Nature 1994;370(6490):571-5.
1994: K J Martell; S Kwak; D J Hakes; Jack E Dixon; Jeffrey M. Trent
Chromosomal localization of four human VH1-like protein-tyrosine phosphatases.
Genomics 1994;22(2):462-4.
1994: Laura J Mauro; Jack E Dixon
'Zip codes' direct intracellular protein tyrosine phosphatases to the correct cellular 'address'.
Trends in biochemical sciences 1994;19(4):151-5.
1994: Zhong-Yin Zhang; W P Malachowski; R L Van Etten; Jack E Dixon
Nature of the rate-determining steps of the reaction catalyzed by the Yersinia protein-tyrosine phosphatase.
The Journal of biological chemistry 1994;269(11):8140-5.
1994: Zhong-Yin Zhang; Y Wang; Jack E Dixon
Dissecting the catalytic mechanism of protein-tyrosine phosphatases.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(5):1624-7.
1994: Zhong-Yin Zhang; D Maclean; Dennis J McNamara; T K Sawyer; Jack E Dixon
Protein tyrosine phosphatase substrate specificity: size and phosphotyrosine positioning requirements in peptide substrates.
Biochemistry 1994;33(8):2285-90.
1994: S P Kwak; D J Hakes; K J Martell; Jack E Dixon
Isolation and characterization of a human dual specificity protein-tyrosine phosphatase gene.
The Journal of biological chemistry 1994;269(5):3596-604.
1994: R J Mourey; Jack E Dixon
Protein tyrosine phosphatases: characterization of extracellular and intracellular domains.
Current opinion in genetics & development 1994;4(1):31-9.
1993: K L Guan; Jack E Dixon
Bacterial and viral protein tyrosine phosphatases.
Seminars in cell biology 1993;4(6):389-96.
1993: R L Stone; H Zalkin; Jack E Dixon
Expression, purification, and kinetic characterization of recombinant human adenylosuccinate lyase.
The Journal of biological chemistry 1993;268(26):19710-6.
1993: Zhong-Yin Zhang; Jack E Dixon
Active site labeling of the Yersinia protein tyrosine phosphatase: the determination of the pKa of the active site cysteine and the function of the conserved histidine 402.
Biochemistry 1993;32(36):9340-5.
1993: S Zhuo; James C Clemens; D J Hakes; D Barford; Jack E Dixon
Expression, purification, crystallization, and biochemical characterization of a recombinant protein phosphatase.
The Journal of biological chemistry 1993;268(24):17754-61.
1993: Y S Park; T D Sweitzer; Jack E Dixon; Claudia Kent
Expression, purification, and characterization of CTP:glycerol-3-phosphate cytidylyltransferase from Bacillus subtilis.
The Journal of biological chemistry 1993;268(22):16648-54.
1993: K M Walton; K J Martell; S P Kwak; Jack E Dixon; B L Largent
A novel receptor-type protein tyrosine phosphatase is expressed during neurogenesis in the olfactory neuroepithelium.
Neuron 1993;11(2):387-400.
1993: Zhong-Yin Zhang; D Maclean; A M Thieme-Sefler; R W Roeske; Jack E Dixon
A continuous spectrophotometric and fluorimetric assay for protein tyrosine phosphatase using phosphotyrosine-containing peptides.
Analytical biochemistry 1993;211(1):7-15.
1993: Zhong-Yin Zhang; A M Thieme-Sefler; D Maclean; Dennis J McNamara; Ellen M Dobrusin; T K Sawyer; Jack E Dixon
Substrate specificity of the protein tyrosine phosphatases.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(10):4446-50.
1993: D J Hakes; K J Martell; W G Zhao; Robert F Massung; Joseph J Esposito; Jack E Dixon
A protein phosphatase related to the vaccinia virus VH1 is encoded in the genomes of several orthopoxviruses and a baculovirus.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(9):4017-21.
1993: S McLaughlin; Jack E Dixon
Alternative splicing gives rise to a nuclear protein tyrosine phosphatase in Drosophila.
The Journal of biological chemistry 1993;268(10):6839-42.
1993: K Guan; D Hakes; Jack E Dixon; H D Park; T G Cooper
The yeast open reading frame encoding a dual specificity phosphatase.
Trends in biochemical sciences 1993;18(1):6.
1993: K M Walton; Jack E Dixon
Protein tyrosine phosphatases.
Annual review of biochemistry 1993;62():101-20.
1992: K Guan; D J Hakes; Y Wang; H D Park; T G Cooper; Jack E Dixon
A yeast protein phosphatase related to the vaccinia virus VH1 phosphatase is induced by nitrogen starvation.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(24):12175-9.
1992: Zhong-Yin Zhang; James C Clemens; H L Schubert; Jeanne A Stuckey; M W Fischer; D M Hume; Mark Saper; Jack E Dixon
Expression, purification, and physicochemical characterization of a recombinant Yersinia protein tyrosine phosphatase.
The Journal of biological chemistry 1992;267(33):23759-66.
1992: K Guan; Robert J Deschenes; Jack E Dixon
Isolation and characterization of a second protein tyrosine phosphatase gene, PTP2, from Saccharomyces cerevisiae.
The Journal of biological chemistry 1992;267(14):10024-30.
1992: D J Hakes; Jack E Dixon
New vectors for high level expression of recombinant proteins in bacteria.
Analytical biochemistry 1992;202(2):293-8.
1992: T A Woodford-Thomas; J D Rhodes; Jack E Dixon
Expression of a protein tyrosine phosphatase in normal and v-src-transformed mouse 3T3 fibroblasts.
The Journal of cell biology 1992;117(2):401-14.
1992: R L Stone; J Aimi; B A Barshop; J Jaeken; G Van den Berghe; H Zalkin; Jack E Dixon
A mutation in adenylosuccinate lyase associated with mental retardation and autistic features.
Nature genetics 1992;1(1):59-63.