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Richard Dixon
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Research Profile (preview)
Chemicals & Drugs
Concepts & Ideas
Living Beings
Procedures
Disorders
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Network (preview)
7
Brock, Tommy
6
Holland, George
5
Kogan, Timothy
5
Wu, Chengde
4
Bui, Huong
3
Blok, Natalie
3
Beck, PJ
3
Hu, X
3
Bourgoyne, Andree
3
Knowles, Vippra
3
Tilton, Ronald
3
Decker, Radford
2
Stavros, FD
2
Raju, BG
2
Vanderslice, Peter
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Publications
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Geonetwork of Richard Dixon (preview)
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All Publications
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2004: Wu Chengde; Decker E Radford; Blok Natalie; Bui Huong; You Tony J; Wang Junmei; Bourgoyne Andree R; Knowles Vippra; Berens Kurt L; Holland George W; Brock Tommy A; Dixon Richard A F
Discovery, modeling, and human pharmacokinetics of N-(2-acetyl-4,6-dimethylphenyl)-3-(3,4-dimethylisoxazol-5-ylsulfamoyl)thiophene-2-carboxamide (TBC3711), a second generation, ETA selective, and orally bioavailable endothelin antagonist.
Journal of medicinal chemistry 2004;47(8):1969-86.
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2004: Vanderslice Peter; Biediger Ronald J; Woodside Darren G; Berens Kurt L; Holland George W; Dixon Richard A F
Development of cell adhesion molecule antagonists as therapeutics for asthma and COPD.
Pulmonary pharmacology & therapeutics 2004;17(1):1-10.
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2003: Wu Chengde; Holland George W; Brock Tommy A; Dixon Richard A F
Recently discovered sulfonamide-, acyl sulfonamide- and carboxylic acid-based endothelin antagonists.
IDrugs : the investigational drugs journal 2003;6(3):232-9.
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2002: You Tony J; Maxwell David S; Kogan Timothy P; Chen Qi; Li Jian; Kassir Jamal; Holland George W; Dixon Richard A F
A 3D structure model of integrin alpha 4 beta 1 complex: I. Construction of a homology model of beta 1 and ligand binding analysis.
Biophysical journal 2002;82(1 Pt 1):447-57.
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2001: Tilton R G; Brock T A; Dixon R A
Therapeutic potential of endothelin receptor antagonists and nitric oxide donors in pulmonary hypertension.
Expert opinion on investigational drugs 2001;10(7):1291-308.
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2001: Wu C; Decker E R; Blok N; Li J; Bourgoyne A R; Bui H; Keller K M; Knowles V; Li W; Stavros F D; Holland G W; Brock T A; Dixon R A
Acyl substitution at the ortho position of anilides enhances oral bioavailability of thiophene sulfonamides: TBC3214, an ETA selective endothelin antagonist.
Journal of medicinal chemistry 2001;44(8):1211-6.
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2000: Zoldhelyi P; Beck P J; Bjercke R J; Ober J C; Hu X; McNatt J M; Akhtar S; Ahmed M; Clubb F J; Chen Z Q; Dixon R A; Yeh E T; Willerson J T
Inhibition of coronary thrombosis and local inflammation by a noncarbohydrate selectin inhibitor.
American journal of physiology. Heart and circulatory physiology 2000;279(6):H3065-75.
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2000: Tilton R G; Munsch C L; Sherwood S J; Chen S J; Chen Y F; Wu C; Block N; Dixon R A; Brock T A
Attenuation of pulmonary vascular hypertension and cardiac hypertrophy with sitaxsentan sodium, an orally active ET(A) receptor antagonist.
Pulmonary pharmacology & therapeutics 2000;13(2):87-97.
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1999: Wu C; Decker E R; Blok N; Bui H; Chen Q; Raju B; Bourgoyne A R; Knowles V; Biediger R J; Market R V; Lin S; Dupré B; Kogan T P; Holland G W; Brock T A; Dixon R A
Endothelin antagonists: substituted mesitylcarboxamides with high potency and selectivity for ET(A) receptors.
Journal of medicinal chemistry 1999;42(22):4485-99.
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1999: Abraham W M; Ahmed A; Sabater J R; Lauredo I T; Botvinnikova Y; Bjercke R J; Hu X; Revelle B M; Kogan T P; Scott I L; Dixon R A; Yeh E T; Beck P J
Selectin blockade prevents antigen-induced late bronchial responses and airway hyperresponsiveness in allergic sheep.
American journal of respiratory and critical care medicine 1999;159(4 Pt 1):1205-14.
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1998: Kogan T P; Dupré B; Bui H; McAbee K L; Kassir J M; Scott I L; Hu X; Vanderslice P; Beck P J; Dixon R A
Novel synthetic inhibitors of selectin-mediated cell adhesion: synthesis of 1,6-bis[3-(3-carboxymethylphenyl)-4-(2-alpha-D- mannopyranosyloxy)phenyl]hexane (TBC1269).
Journal of medicinal chemistry 1998;41(7):1099-111.
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1997: Tilton R G; Dixon R A; Brock T A
Growth factor antagonists for the treatment of diabetic vascular complications.
Expert opinion on investigational drugs 1997;6(11):1671-84.
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1997: Wu C; Chan M F; Stavros F; Raju B; Okun I; Mong S; Keller K M; Brock T; Kogan T P; Dixon R A
Discovery of TBC11251, a potent, long acting, orally active endothelin receptor-A selective antagonist.
Journal of medicinal chemistry 1997;40(11):1690-7.
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