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James Dobson

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Myocardial Contraction

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Richard A Fenton; James G Dobson
Reduced adenosine release from the aged mammalian heart.
Satoshi Komatsu; Lynne G Shea; James G Dobson; Mitsuo Ikebe; Richard A Fenton
Crosstalk between adenosine A1 and β1-adrenergic receptors regulates translocation of PKCε in isolated rat cardiomyocytes.
Richard A Fenton; Lynne G Shea; Cecilia Doddi; James G Dobson
Myocardial adenosine A(1)-receptor-mediated adenoprotection involves phospholipase C, PKC-epsilon, and p38 MAPK, but not HSP27.

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All Publications

2012: Richard A Fenton; James G Dobson
Reduced adenosine release from the aged mammalian heart.
Journal of cellular physiology 2012;227(11):3709-14.
2012: Satoshi Komatsu; Lynne G Shea; James G Dobson; Mitsuo Ikebe; Richard A Fenton
Crosstalk between adenosine A1 and β1-adrenergic receptors regulates translocation of PKCε in isolated rat cardiomyocytes.
Journal of cellular physiology 2012;227(9):3201-7.
2010: Richard A Fenton; Lynne G Shea; Cecilia Doddi; James G Dobson
Myocardial adenosine A(1)-receptor-mediated adenoprotection involves phospholipase C, PKC-epsilon, and p38 MAPK, but not HSP27.
American journal of physiology. Heart and circulatory physiology 2010;298(6):H1671-8.
2009: Richard A Fenton; Satoshi Komatsu; Mitsuo Ikebe; Lynne G Shea; James G Dobson
Adenoprotection of the heart involves phospholipase C-induced activation and translocation of PKC-epsilon to RACK2 in adult rat and mouse.
American journal of physiology. Heart and circulatory physiology 2009;297(2):H718-25.
2008: Eugene I Tikh; Richard A Fenton; Jiang-Fan Chen; Michael A Schwarzschild; James G Dobson
Adenosine A1 and A2A receptor regulation of protein phosphatase 2A in the murine heart.
Journal of cellular physiology 2008;216(1):83-90.
2007: Richard A Fenton; James G Dobson
Adenosine A1 and A2A receptor effects on G-protein cycling in beta-adrenergic stimulated ventricular membranes.
Journal of cellular physiology 2007;213(3):785-92.
2007: Thomas K Knott; Héctor G Marrero; Richard A Fenton; Edward E Custer; James G Dobson; José R Lemos
Endogenous adenosine inhibits CNS terminal Ca(2+) currents and exocytosis.
Journal of cellular physiology 2007;210(2):309-14.
2006: Eugene I Tikh; Richard A Fenton; James G Dobson
Contractile effects of adenosine A1 and A2A receptors in isolated murine hearts.
American journal of physiology. Heart and circulatory physiology 2006;290(1):H348-56.
2005: Richard A Fenton; Eric W Dickson; James G Dobson
Inhibition of phosphatase activity enhances preconditioning and limits cell death in the ischemic/reperfused aged rat heart.
Life sciences 2005;77(26):3375-88.
2004: Mojca Lorbar; Eugene S Chung; Arash Nabi; Katarina Skalova; Richard A Fenton; James G Dobson; Theo E Meyer
Receptors subtypes involved in adenosine-mediated modulation of norepinephrine release from cardiac nerve terminals.
Canadian journal of physiology and pharmacology 2004;82(11):1026-31.
2004: Koji Miyazaki; Satoshi Komatsu; Mitsuo Ikebe; Richard A Fenton; James G Dobson
Protein kinase Cepsilon and the antiadrenergic action of adenosine in rat ventricular myocytes.
American journal of physiology. Heart and circulatory physiology 2004;287(4):H1721-9.
2003: James G Dobson; John Fray; Jack L Leonard; Richard E Pratt
Molecular mechanisms of reduced beta-adrenergic signaling in the aged heart as revealed by genomic profiling.
Physiological genomics 2003;15(2):142-7.
2003: James G Dobson; Lynne G Shea; Richard A Fenton
Beta-adrenergic and antiadrenergic modulation of cardiac adenylyl cyclase is influenced by phosphorylation.
American journal of physiology. Heart and circulatory physiology 2003;285(4):H1471-8.
2002: Patricia S Reisert; James G Dobson; Richard A Fenton
Anoxia-induced changes in purine nucleoside metabolism of in vitro aged human fibroblasts.
Life sciences 2002;70(12):1369-82.
2001: Theo E Meyer; Eugene S Chung; Stefano Perlini; Gavin R Norton; Angela J Woodiwiss; Mojca Lorbar; Richard A Fenton; James G Dobson
Antiadrenergic effects of adenosine in pressure overload hypertrophy.
Hypertension 2001;37(3):862-8.
2000: J Li; Charles S C Garnette; M Cahn; R Brannon Claytor; Michael J Rohrer; James G Dobson; B Gerlitz; Bruce S Cutler
Recombinant thrombomodulin inhibits arterial smooth muscle cell proliferation induced by thrombin.
Journal of vascular surgery 2000;32(4):804-13.
2000: Thomas Monahan; D R Sawmiller; Richard A Fenton; James G Dobson
Adenosine A(2a)-receptor activation increases contractility in isolated perfused hearts.
American journal of physiology. Heart and circulatory physiology 2000;279(4):H1472-81.
2000: Mojca Lorbar; K Skalova; A Nabi; Eugene S Chung; Richard A Fenton; James G Dobson; Theo E Meyer
Norepinephrine concentrations in the epicardial transudate reflect early changes in adrenergic activity in the isolated perfused heart.
Journal of molecular and cellular cardiology 2000;32(9):1695-701.
2000: Richard A Fenton; Eric W Dickson; Theo E Meyer; James G Dobson
Aging reduces the cardioprotective effect of ischemic preconditioning in the rat heart.
Journal of molecular and cellular cardiology 2000;32(7):1371-5.
1999: Mojca Lorbar; Richard A Fenton; James G Dobson
ATP as a source of interstitial adenosine in the rat heart.
Canadian journal of physiology and pharmacology 1999;77(8):579-88.
1999: Angela J Woodiwiss; T W Honeyman; Richard A Fenton; James G Dobson
Adenosine A2a-receptor activation enhances cardiomyocyte shortening via Ca2+-independent and -dependent mechanisms.
The American journal of physiology 1999;276(5 Pt 2):H1434-41.
1999: Mojca Lorbar; Richard A Fenton; A J Duffy; Christopher Graybill; James G Dobson
Effect of aging on myocardial adenosine production, adenosine uptake and adenosine kinase activity in rats.
Journal of molecular and cellular cardiology 1999;31(2):401-12.
1999: Gavin R Norton; Angela J Woodiwiss; R J McGinn; Mojca Lorbar; Eugene S Chung; T W Honeyman; Richard A Fenton; James G Dobson; Theo E Meyer
Adenosine A1 receptor-mediated antiadrenergic effects are modulated by A2a receptor activation in rat heart.
The American journal of physiology 1999;276(2 Pt 2):H341-9.
1998: J m Li; Richard A Fenton; H B Wheeler; Craig C Powell; BD Peyton; Bruce S Cutler; James G Dobson
Adenosine A2a receptors increase arterial endothelial cell nitric oxide.
The Journal of surgical research 1998;80(2):357-64.
1998: Eugene S Chung; Stefano Perlini; Gerard P Aurigemma; Richard A Fenton; James G Dobson; Theo E Meyer
Effects of chronic adenosine uptake blockade on adrenergic responsiveness and left ventricular chamber function in pressure overload hypertrophy in the rat.
Journal of hypertension 1998;16(12 Pt 1):1813-22.
1998: Stefano Perlini; E P Khoury; Gavin R Norton; Eugene S Chung; Richard A Fenton; James G Dobson; Theo E Meyer
Adenosine mediates sustained adrenergic desensitization in the rat heart via activation of protein kinase C.
Circulation research 1998;83(7):761-71.
1998: D R Sawmiller; Richard A Fenton; James G Dobson
Myocardial adenosine A1-receptor sensitivity during juvenile and adult stages of maturation.
The American journal of physiology 1998;274(2 Pt 2):H627-35.
1997: James G Dobson; Richard A Fenton
Adenosine A2 receptor function in rat ventricular myocytes.
Cardiovascular research 1997;34(2):337-47.
1997: Michael F Ethier; James G Dobson
Adenosine stimulation of DNA synthesis in human endothelial cells.
The American journal of physiology 1997;272(3 Pt 2):H1470-9.
1996: James G Dobson; Richard A Fenton; D R Sawmiller
The contractile response of the ventricular myocardium to adenosine A1 and A2 receptor stimulation.
Annals of the New York Academy of Sciences 1996;793():64-73.
1996: D R Sawmiller; Richard A Fenton; James G Dobson
Myocardial adenosine A1 and A2 receptor activities during juvenile and adult stages of development.
The American journal of physiology 1996;271(1 Pt 2):H235-43.
1996: Fred D Romano; James G Dobson
Adenosine attenuation of isoproterenol-stimulated adenylyl cyclase activity is enhanced with aging in the adult heart.
Life sciences 1996;58(6):493-502.
1995: Richard A Fenton; K J Galeckas; James G Dobson
Endogenous adenosine reduces depression of cardiac function induced by beta-adrenergic stimulation during low flow perfusion.
Journal of molecular and cellular cardiology 1995;27(10):2373-83.
1995: J M Li; Richard A Fenton; Bruce S Cutler; James G Dobson
Adenosine enhances nitric oxide production by vascular endothelial cells.
The American journal of physiology 1995;269(2 Pt 1):C519-23.
1993: James G Dobson; Richard A Fenton
Adenosine inhibition of beta-adrenergic induced responses in aged hearts.
The American journal of physiology 1993;265(2 Pt 2):H494-503.
1993: Michael F Ethier; V Chander; James G Dobson
Adenosine stimulates proliferation of human endothelial cells in culture.
The American journal of physiology 1993;265(1 Pt 2):H131-8.
1993: Richard A Fenton; James G Dobson
Hypoxia enhances isoproterenol-induced increase in heart interstitial adenosine, depressing beta-adrenergic contractile responses.
Circulation research 1993;72(3):571-8.
1992: Richard A Fenton; James G Dobson
Fluorometric quantitation of adenosine concentration in small samples of extracellular fluid.
Analytical biochemistry 1992;207(1):134-41.
1992: E E George; James G Dobson
Lack of oscillations in cyclic AMP, cAMP-protein kinase and glycogen phosphorylase during the cardiac cycle in perfused rat hearts.
Journal of molecular and cellular cardiology 1992;24(5):477-84.
1992: Michael F Ethier; M Medeiros; Fred D Romano; James G Dobson
Mechanism of enhanced cyclic AMP stimulation by isoproterenol in aged human fibroblasts.
Experimental gerontology 1992;27(3):287-300.
1991: Richard A Fenton; E D Moore; Fred S Fay; James G Dobson
Adenosine reduces the Ca2+ transients of isoproterenol-stimulated rat ventricular myocytes.
The American journal of physiology 1991;261(6 Pt 1):C1107-14.
1991: E E George; Fred D Romano; James G Dobson
Adenosine and acetylcholine reduce isoproterenol-induced protein phosphorylation of rat myocytes.
Journal of molecular and cellular cardiology 1991;23(6):749-64.
1991: Fred D Romano; T S Naimi; James G Dobson
Adenosine attenuation of catecholamine-enhanced contractility of rat heart in vivo.
The American journal of physiology 1991;260(5 Pt 2):H1635-9.
1990: Fred D Romano; James G Dobson
Adenosine modulates beta-adrenergic signal transduction in guinea-pig heart ventricular membranes.
Journal of molecular and cellular cardiology 1990;22(12):1359-70.
1990: James G Dobson; Richard A Fenton; Fred D Romano
Increased myocardial adenosine production and reduction of beta-adrenergic contractile response in aged hearts.
Circulation research 1990;66(5):1381-90.
1990: Richard A Fenton; S Tsimikas; James G Dobson
Influence of beta-adrenergic stimulation and contraction frequency on rat heart interstitial adenosine.
Circulation research 1990;66(2):457-68.
1989: Michael F Ethier; R B Hickler; James G Dobson
Aging increases adenosine and inosine release by human fibroblast cultures.
Mechanisms of ageing and development 1989;50(2):159-68.
1989: Fred D Romano; S G MacDonald; James G Dobson
Adenosine receptor coupling to adenylate cyclase of rat ventricular myocyte membranes.
The American journal of physiology 1989;257(4 Pt 2):H1088-95.
1988: Fred D Romano; Richard A Fenton; James G Dobson
The adenosine Ri agonist, phenylisopropyladenosine, reduces high affinity isoproterenol binding to the beta-adrenergic receptor of rat myocardial membranes.
Second messengers and phosphoproteins 1988;12(1):29-43.
1987: Richard A Fenton; James G Dobson
Measurement by fluorescence of interstitial adenosine levels in normoxic, hypoxic, and ischemic perfused rat hearts.
Circulation research 1987;60(2):177-84.
1987: James G Dobson; Richard A Fenton; Fred D Romano
The cardiac anti-adrenergic effect of adenosine.
Progress in clinical and biological research 1987;230():331-43.
1986: James G Dobson; R W Ordway; Richard A Fenton
Endogenous adenosine inhibits catecholamine contractile responses in normoxic hearts.
The American journal of physiology 1986;251(2 Pt 2):H455-62.
1985: Richard A Fenton; James G Dobson
Nicotine increases heart adenosine release, oxygen consumption, and contractility.
The American journal of physiology 1985;249(3 Pt 2):H463-9.
1984: Richard A Fenton; James G Dobson
Adenosine and calcium alter adrenergic-induced intact heart protein phosphorylation.
The American journal of physiology 1984;246(4 Pt 2):H559-65.