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Guy Dodson

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X Ray Crystallography

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John G Menting; Brian J Smith; Donald F Steiner; Colin W Ward; Christopher J Watson; Michael A Weiss; Linda J Whittaker; Jonathan Whittaker; Lenka Záková; Andrzej M Brzozowski; Shu Jin Chan; Guy G Dodson; Jirí Jirácek; Emília Kletvíková; Geoffrey K-W Kong; Mai B Margetts; Michael C Lawrence
How insulin engages its primary binding site on the insulin receptor.
Guy G Dodson
Biochemical contacts and collaborations between China and the U.K. since 1911.
Chao-Sheng Chen; Guy G Dodson; Paul Gollnick; Natalie Merlino; Mikhail B Shevtsov; Callum Smits; Alfred A Antson
How to change the oligomeric state of a circular protein assembly: switch from 11-subunit to 12-subunit TRAP suggests a general mechanism.

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2013: John G Menting; Brian J Smith; Donald F Steiner; Colin W Ward; Christopher J Watson; Michael A Weiss; Linda J Whittaker; Jonathan Whittaker; Lenka Záková; Andrzej M Brzozowski; Shu Jin Chan; Guy G Dodson; Jirí Jirácek; Emília Kletvíková; Geoffrey K-W Kong; Mai B Margetts; Michael C Lawrence
How insulin engages its primary binding site on the insulin receptor.
Nature 2013;493(7431):241-5.
2011: Guy G Dodson
Biochemical contacts and collaborations between China and the U.K. since 1911.
Biochemical Society transactions 2011;39(5):1313-22.
2011: Chao-Sheng Chen; Guy G Dodson; Paul Gollnick; Natalie Merlino; Mikhail B Shevtsov; Callum Smits; Alfred A Antson
How to change the oligomeric state of a circular protein assembly: switch from 11-subunit to 12-subunit TRAP suggests a general mechanism.
PloS one 2011;6(10):e25296.
2010: Jirí Jirácek; Lenka Záková; Emília Antolíková; Christopher J Watson; Johan P Turkenburg; Guy G Dodson; Andrzej M Brzozowski
Implications for the active form of human insulin based on the structural convergence of highly active hormone analogues.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(5):1966-70.
2008: Guy G Dodson; David P Lane; chandra verma
Molecular simulations of protein dynamics: new windows on mechanisms in biology.
EMBO reports 2008;9(2):144-50.
2008: Chrislaine Withers-Martinez; Lesley F Haire; Fiona Hackett; Philip A Walker; Steven A Howell; Stephen John Smerdon; Guy G Dodson; Michael J Blackman
Malarial EBA-175 region VI crystallographic structure reveals a KIX-like binding interface.
Journal of molecular biology 2008;375(3):773-81.
2007: R Suresh Kumar; CG Suresh; James A Brannigan; Guy G Dodson; Sushama M Gaikwad
Bile salt hydrolase, the member of Ntn-hydrolase family: differential modes of structural and functional transitions during denaturation.
IUBMB life 2007;59(2):118-25.
2006: R Suresh Kumar; James A Brannigan; Asmita Prabhune; archana vishnu pundle; Guy G Dodson; Eleanor J Dodson; CG Suresh
Structural and functional analysis of a conjugated bile salt hydrolase from Bifidobacterium longum reveals an evolutionary relationship with penicillin V acylase.
The Journal of biological chemistry 2006;281(43):32516-25.
2006: Alfonso De Simone; Guy G Dodson; Franca Fraternali; Adriana Zagari
Water molecules as structural determinants among prions of low sequence identity.
FEBS letters 2006;580(10):2488-94.
2006: Jean L Whittingham; Zhang Youshang; Lenka Záková; Eleanor J Dodson; Johan P Turkenburg; Jens Brange; Guy G Dodson
I222 crystal form of despentapeptide (B26-B30) insulin provides new insights into the properties of monomeric insulin.
Acta crystallographica. Section D, Biological crystallography 2006;62(Pt 5):505-11.
2006: Guy G Dodson; chandra verma
Protein flexibility: its role in structure and mechanism revealed by molecular simulations.
Cellular and molecular life sciences : CMLS 2006;63(2):207-19.
2005: Priya Rathinaswamy; archana vishnu pundle; Asmita Prabhune; Hepzibah Sivaraman; James A Brannigan; Guy G Dodson; CG Suresh
Cloning, purification, crystallization and preliminary structural studies of penicillin V acylase from Bacillus subtilis.
Acta crystallographica. Section F, Structural biology and crystallization communications 2005;61(Pt 7):680-3.
2005: Alfonso De Simone; Guy G Dodson; chandra verma; Adriana Zagari; Franca Fraternali
Prion and water: tight and dynamical hydration sites have a key role in structural stability.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(21):7535-40.
2005: P Manish Chandra; James A Brannigan; Asmita Prabhune; archana vishnu pundle; Johan P Turkenburg; Guy G Dodson; CG Suresh
Cloning, preparation and preliminary crystallographic studies of penicillin V acylase autoproteolytic processing mutants.
Acta crystallographica. Section F, Structural biology and crystallization communications 2005;61(Pt 1):124-7.
2004: Lenka Záková; Jirí Brynda; Oskar Au-Alvarez; Eleanor J Dodson; Guy G Dodson; Jean L Whittingham; Andrzej M Brzozowski
Toward the insulin-IGF-I intermediate structures: functional and structural properties of the [TyrB25NMePheB26] insulin mutant.
Biochemistry 2004;43(51):16293-300.
2004: R Suresh Kumar; James A Brannigan; archana vishnu pundle; Asmita Prabhune; Guy G Dodson; CG Suresh
Expression, purification, crystallization and preliminary X-ray diffraction analysis of conjugated bile salt hydrolase from Bifidobacterium longum.
Acta crystallographica. Section D, Biological crystallography 2004;60(Pt 9):1665-7.
2004: Carien Dekker; Chairat Uthaipibull; Lesley J Calder; Matthew J Lock; Munira Grainger; William D Morgan; Guy G Dodson; Anthony A Holder
Inhibitory and neutral antibodies to Plasmodium falciparum MSP119 form ring structures with their antigen.
Molecular and biochemical parasitology 2004;137(1):143-9.
2004: Richard B Greaves; Guy G Dodson; chandra verma
Altered ionization of the B13 Glu in insulin B9 and B10 mutants: a computational analysis.
Protein engineering, design & selection : PEDS 2004;17(7):557-63.
2004: Jean L Whittingham; Ib Jonassen; Svend Havelund; Shirley M Roberts; Eleanor J Dodson; chandra verma; Anthony J Wilkinson; Guy G Dodson
Crystallographic and solution studies of N-lithocholyl insulin: a new generation of prolonged-acting human insulins.
Biochemistry 2004;43(20):5987-95.
2004: Lesley F Haire; Sheena M Whyte; Nishi Vasisht; Andrew C Gill; chandra verma; Eleanor J Dodson; Guy G Dodson; Peter M Bayley
The crystal structure of the globular domain of sheep prion protein.
Journal of molecular biology 2004;336(5):1175-83.
2003: Sheena M Whyte; Ian D Sylvester; Stephen Martin; Andrew C Gill; Franziska Wopfner; Hermann M Schätzl; Guy G Dodson; Peter M Bayley
Stability and conformational properties of doppel, a prion-like protein, and its single-disulphide mutant.
The Biochemical journal 2003;373(Pt 2):485-94.
2003: Olga V Moroz; Alfred A Antson; S J Grist; Norman J Maitland; Guy G Dodson; Keith S Wilson; EM Lukanidin; Igor Bronstein
Structure of the human S100A12-copper complex: implications for host-parasite defence.
Acta crystallographica. Section D, Biological crystallography 2003;59(Pt 5):859-67.
2003: Olga V Moroz; Guy G Dodson; Keith S Wilson; EM Lukanidin; Igor Bronstein
Multiple structural states of S100A12: A key to its functional diversity.
Microscopy research and technique 2003;60(6):581-92.
2002: Garib N Murshudov; Albina I Grebenko; James A Brannigan; Alfred A Antson; Vladimir V Barynin; Guy G Dodson; Zbigniew Dauter; Keith S Wilson; William Melik-Adamyan
The structures of Micrococcus lysodeikticus catalase, its ferryl intermediate (compound II) and NADPH complex.
Acta crystallographica. Section D, Biological crystallography 2002;58(Pt 12):1972-82.
2002: Andrzej M Brzozowski; Eleanor J Dodson; Guy G Dodson; Garib N Murshudov; chandra verma; Johan P Turkenburg; Frederik M de Bree; Zbigniew Dauter
Structural origins of the functional divergence of human insulin-like growth factor-I and insulin.
Biochemistry 2002;41(30):9389-97.
2002: KM Polyakov; Andrey A Lebedev; A L Okorokov; K I Panov; Alexey A Schulga; A G Pavlovsky; M Ya Karpeisky; Guy G Dodson
The structure of substrate-free microbial ribonuclease binase and of its complexes with 3'GMP and sulfate ions.
Acta crystallographica. Section D, Biological crystallography 2002;58(Pt 5):744-50.
2002: Olga V Moroz; Alfred A Antson; Eleanor J Dodson; H J Burrell; S J Grist; R M Lloyd; Norman J Maitland; Guy G Dodson; Keith S Wilson; EM Lukanidin; Igor Bronstein
The structure of S100A12 in a hexameric form and its proposed role in receptor signalling.
Acta crystallographica. Section D, Biological crystallography 2002;58(Pt 3):407-13.
2002: Youshang Zhang; Jean L Whittingham; Johan P Turkenburg; Eleanor J Dodson; Jens Brange; Guy G Dodson
Crystallization and preliminary crystallographic investigation of a low-pH native insulin monomer with flexible behaviour.
Acta crystallographica. Section D, Biological crystallography 2002;58(Pt 1):186-7.
2001: B Gopal; Lesley F Haire; Steven J Gamblin; Eleanor J Dodson; Andrew N Lane; KG Papavinasasundaram; M Joseph Colston; Guy G Dodson
Crystal structure of the transcription elongation/anti-termination factor NusA from Mycobacterium tuberculosis at 1.7 A resolution.
Journal of molecular biology 2001;314(5):1087-95.
2001: Colin E McVey; M A Walsh; Guy G Dodson; Keith S Wilson; James A Brannigan
Crystal structures of penicillin acylase enzyme-substrate complexes: structural insights into the catalytic mechanism.
Journal of molecular biology 2001;313(1):139-50.
2001: B Gopal; KG Papavinasasundaram; M Joseph Colston; Guy G Dodson; Lesley F Haire
Crystallization and preliminary X-ray diffraction studies on the N-utilizing substance A (NusA) from Mycobacterium tuberculosis.
Acta crystallographica. Section D, Biological crystallography 2001;57(Pt 8):1187-8.
2001: S Tarabykina; David Scott; P Herzyk; TJ Hill; J R Tame; Marina Kriajevska; Daniel Lafitte; Peter J Derrick; Guy G Dodson; N J Maitland; Eugene Lukanidin; Igor Bronstein
The dimerization interface of the metastasis-associated protein S100A4 (Mts1): in vivo and in vitro studies.
The Journal of biological chemistry 2001;276(26):24212-22.
2001: B Gopal; KG Papavinasasundaram; Guy G Dodson; M Joseph Colston; Sarah Major; Andrew N Lane
Spectroscopic and thermodynamic characterization of the transcription antitermination factor NusE and its interaction with NusB from Mycobacterium tuberculosis.
Biochemistry 2001;40(4):920-8.
2001: Olga V Moroz; Alfred A Antson; Garib N Murshudov; Norman J Maitland; Guy G Dodson; Keith S Wilson; I Skibshøj; EM Lukanidin; Igor Bronstein
The three-dimensional structure of human S100A12.
Acta crystallographica. Section D, Biological crystallography 2001;57(Pt 1):20-9.
2000: L Hewitt; Volker Kasche; K Lummer; Richard J Lewis; Garib N Murshudov; chandra verma; Guy G Dodson; Keith S Wilson
Structure of a slow processing precursor penicillin acylase from Escherichia coli reveals the linker peptide blocking the active-site cleft.
Journal of molecular biology 2000;302(4):887-98.
2000: David I Roper; Trevor Huyton; Alexei A Vagin; Guy G Dodson
The molecular basis of vancomycin resistance in clinically relevant Enterococci: crystal structure of D-alanyl-D-lactate ligase (VanA).
Proceedings of the National Academy of Sciences of the United States of America 2000;97(16):8921-5.
2000: S Tarabykina; Marina Kriajevska; David Scott; TJ Hill; Daniel Lafitte; Peter J Derrick; Guy G Dodson; Eugene Lukanidin; Igor Bronstein
Heterocomplex formation between metastasis-related protein S100A4 (Mts1) and S100A1 as revealed by the yeast two-hybrid system.
FEBS letters 2000;475(3):187-91.
2000: B Gopal; Lesley F Haire; robert cox; M Jo Colston; Sarah Major; J A Brannigan; Stephen John Smerdon; Guy G Dodson
The crystal structure of NusB from Mycobacterium tuberculosis.
Nature structural biology 2000;7(6):475-8.
2000: Alfred A Antson; JE Burns; Olga V Moroz; David Scott; Cyril M Sanders; Igor Bronstein; Guy G Dodson; Keith S Wilson; Norman J Maitland
Structure of the intact transactivation domain of the human papillomavirus E2 protein.
Nature 2000;403(6771):805-9.
2000: Olga V Moroz; Alfred A Antson; Guy G Dodson; Keith S Wilson; I Skibshoj; EM Lukanidin; Igor Bronstein
Crystallization and preliminary X-ray diffraction analysis of human calcium-binding protein S100A12.
Acta crystallographica. Section D, Biological crystallography 2000;56(Pt 2):189-91.
2000: B Gopal; robert cox; M Joseph Colston; Guy G Dodson; Stephen John Smerdon; Lesley F Haire
Crystallization and preliminary X-ray diffraction studies on the N-utilizing substance-B (NusB) from Mycobacterium tuberculosis.
Acta crystallographica. Section D, Biological crystallography 2000;56(Pt 1):64-6.
1999: Alfred A Antson; Eleanor J Dodson; Guy G Dodson; Richard B Greaves; X Chen; Paul Gollnick
Structure of the trp RNA-binding attenuation protein, TRAP, bound to RNA.
Nature 1999;401(6750):235-42.
1999: L Tang; Jean L Whittingham; chandra verma; Leo S D Caves; Guy G Dodson
Structural consequences of the B5 histidine --> tyrosine mutation in human insulin characterized by X-ray crystallography and conformational analysis.
Biochemistry 1999;38(37):12041-51.
1999: X p Chen; Alfred A Antson; M Yang; P Li; C Baumann; Eleanor J Dodson; Guy G Dodson; Paul Gollnick
Regulatory features of the trp operon and the crystal structure of the trp RNA-binding attenuation protein from Bacillus stearothermophilus.
Journal of molecular biology 1999;289(4):1003-16.
1999: CG Suresh; archana vishnu pundle; Hepzibah Sivaraman; KN Rao; James A Brannigan; Colin E McVey; chandra verma; Z Dauter; Eleanor J Dodson; Guy G Dodson
Penicillin V acylase crystal structure reveals new Ntn-hydrolase family members.
Nature structural biology 1999;6(5):414-6.
1999: Igor Bronstein; A Wynne-Jones; Alyona Sukhanova; Fabrice Fleury; Anatoli Ianoul; Joseph A Holden; Alain J.P. Alix; Guy G Dodson; JC Jardillier; Igor Nabiev; Anthony J Wilkinson
Expression, purification and DNA-cleavage activity of recombinant 68-kDa human topoisomerase I-target for antitumor drugs.
Anticancer research 1999;19(1A):317-27.
1998: Fabrice Fleury; Anatoli Ianoul; E Kryukov; Alyona Sukhanova; Irina A Kudelina; A Wynne-Jones; Igor Bronstein; M Maizieres; M Berjot; Guy G Dodson; Anthony J Wilkinson; Joseph A Holden; Alexei V Feofanov; Alain J.P. Alix; JC Jardillier; Igor Nabiev
Raman and CD spectroscopy of recombinant 68-kDa DNA human topoisomerase I and its complex with suicide DNA-substrate.
Biochemistry 1998;37(41):14630-42.
1998: Guy G Dodson; A Wlodawer
Catalytic triads and their relatives.
Trends in biochemical sciences 1998;23(9):347-52.
1998: Jean L Whittingham; David Edwards; Alfred A Antson; J M Clarkson; Guy G Dodson
Interactions of phenol and m-cresol in the insulin hexamer, and their effect on the association properties of B28 pro --> Asp insulin analogues.
Biochemistry 1998;37(33):11516-23.
1998: Michail N Isupov; Alfred A Antson; Eleanor J Dodson; Guy G Dodson; Irene S Dementieva; Lyudmila N Zakomirdina; K S Wilson; Z Dauter; Andrey A Lebedev; EH Harutyunyan
Crystal structure of tryptophanase.
Journal of molecular biology 1998;276(3):603-23.
1998: MF Perutz; Anthony J Wilkinson; M Paoli; Guy G Dodson
The stereochemical mechanism of the cooperative effects in hemoglobin revisited.
Annual review of biophysics and biomolecular structure 1998;27():1-34.
1997: M Paoli; Guy G Dodson; R C Liddington; Anthony J Wilkinson
Tension in haemoglobin revealed by Fe-His(F8) bond rupture in the fully liganded T-state.
Journal of molecular biology 1997;271(2):161-7.
1997: Bakthavatsalam Sundararaju; Alfred A Antson; Robert S Phillips; Tatyana V Demidkina; Maria V Barbolina; Paul Gollnick; Guy G Dodson; K S Wilson
The crystal structure of Citrobacter freundii tyrosine phenol-lyase complexed with 3-(4'-hydroxyphenyl)propionic acid, together with site-directed mutagenesis and kinetic analysis, demonstrates that arginine 381 is required for substrate specificity.
Biochemistry 1997;36(21):6502-10.
1997: Jens Brange; Guy G Dodson; David Edwards; P H Holden; Jean L Whittingham
A model of insulin fibrils derived from the x-ray crystal structure of a monomeric insulin (despentapeptide insulin).
Proteins 1997;27(4):507-16.
1997: A L Okorokov; K I Panov; Wendy A Offen; V G Mukhortov; Alfred A Antson; Anthony J Wilkinson; Guy G Dodson
RNA cleavage without hydrolysis. Splitting the catalytic activities of binase with Asn101 and Thr101 mutations.
Protein engineering 1997;10(3):273-8.
1997: M Hirshberg; R W Stockley; Guy G Dodson; Martin R Webb
The crystal structure of human rac1, a member of the rho-family complexed with a GTP analogue.
Nature structural biology 1997;4(2):147-52.
1997: T Barrett; Bing Xiao; Eleanor J Dodson; Guy G Dodson; S B Ludbrook; K Nurmahomed; Steven J Gamblin; A Musacchio; Stephen John Smerdon; John F Eccleston
The structure of the GTPase-activating domain from p50rhoGAP.
Nature 1997;385(6615):458-61.
1996: EH Harutyunyan; T N Safonova; I P Kuranova; A N Popov; Alexey Teplyakov; G V Obmolova; B K Valnshtein; Guy G Dodson; J C Wilson
The binding of carbon monoxide and nitric oxide to leghaemoglobin in comparison with other haemoglobins.
Journal of molecular biology 1996;264(1):152-61.
1996: E N Baker; T L Blundell; M Vijayan; E Dodson; Guy G Dodson; Gary L Gilliland; Joel Sussman
Archival journal requirements for data deposition.
Biophysical journal 1996;70(6):2994.
1996: A L Okorokov; K I Panov; KM Polyakov; Anthony J Wilkinson; Guy G Dodson
Site-directed mutagenesis of the base recognition loop of ribonuclease from Bacillus intermedius (binase).
FEBS letters 1996;384(2):143-6.
1996: Alfred A Antson; Eleanor J Dodson; Guy G Dodson
Circular assemblies.
Current opinion in structural biology 1996;6(2):142-50.
1996: M Paoli; R Liddington; Jeremy R H Tame; A Wilkinson; Guy G Dodson
Crystal structure of T state haemoglobin with oxygen bound at all four haems.
Journal of molecular biology 1996;256(4):775-92.
1996: E N Baker; T L Blundell; M Vijayan; Eleanor J Dodson; Guy G Dodson; Gary L Gilliland; Joel Sussman
International Seminar-cum-School on Macromolecular Crystallographic Data at Calcutta, India.
Anti-cancer drug design 1996;11(2):173-4.
1996: E N Baker; T L Blundell; M Vijayan; E Dodson; Guy G Dodson; Gary L Gilliland; Joel Sussman
A formal discussion of the archival journal requirements for data deposition.
Biochemical and biophysical research communications 1996;219(3):976-7.
1996: E N Baker; T L Bluntell; M Vijayan; E Dodson; Guy G Dodson; Gary L Gilliland; Joel Sussman
Publication of macromolecular crystal structures.
FEBS letters 1996;380(3):301.
1996: E N Baker; T L Blundell; Eleanor J Dodson; Guy G Dodson; G L Gilliland; Joel Sussman; M Vijayan
Diffraction data deposition.
Structure (London, England : 1993) 1996;4(2):217.
1996: E N Baker; T L Blundell; M Vijayan; E Dodson; Guy G Dodson; Gary L Gilliland; Joel Sussman
Archival journal requirements of macromolecular crystallographic data.
Journal of biomolecular structure & dynamics 1996;13(4):583.
1996: E N Baker; T L Blundell; M Vijayan; Eleanor J Dodson; Guy G Dodson; G I Gilliland; Joel Sussman
Crystallographic data deposition.
Nature 1996;379(6562):202.
1996: Gideon J Davies; Guy G Dodson; M H Moore; S P Tolley; Zbigniew Dauter; Keith S Wilson; G Rasmussen; Martin Schülein
Structure determination and refinement of the Humicola insolens endoglucanase V at 1.5 A resolution.
Acta crystallographica. Section D, Biological crystallography 1996;52(Pt 1):7-17.
1995: Jean L Whittingham; S Chaudhuri; Eleanor J Dodson; P C Moody; Guy G Dodson
X-ray crystallographic studies on hexameric insulins in the presence of helix-stabilizing agents, thiocyanate, methylparaben, and phenol.
Biochemistry 1995;34(47):15553-63.
1995: James A Brannigan; Guy G Dodson; H J Duggleby; P C Moody; Janet L Smith; D R Tomchick; A G Murzin
A protein catalytic framework with an N-terminal nucleophile is capable of self-activation.
Nature 1995;378(6555):416-9.
1995: EH Harutyunyan; T N Safonova; I P Kuranova; A N Popov; Alexey Teplyakov; G V Obmolova; A A Rusakov; B K Vainshtein; Guy G Dodson; J C Wilson
The structure of deoxy- and oxy-leghaemoglobin from lupin.
Journal of molecular biology 1995;251(1):104-15.
1995: B Xiao; Stephen John Smerdon; D H Jones; Guy G Dodson; Yasmina Soneji; Alastair Aitken; Steven J Gamblin
Structure of a 14-3-3 protein and implications for coordination of multiple signalling pathways.
Nature 1995;376(6536):188-91.
1995: Alfred A Antson; J Otridge; Andrzej M Brzozowski; Eleanor J Dodson; Guy G Dodson; Keith S Wilson; T M Smith; M Yang; T Kurecki; Paul Gollnick
The structure of trp RNA-binding attenuation protein.
Nature 1995;374(6524):693-700.
1995: H J Duggleby; S P Tolley; C P Hill; Eleanor J Dodson; Guy G Dodson; P C Moody
Penicillin acylase has a single-amino-acid catalytic centre.
Nature 1995;373(6511):264-8.
1994: Guy G Dodson
Dorothy Hodgkin 1910-1994.
Structure (London, England : 1993) 1994;2(9):891-3.
1994: G Lange; S J Lewis; Garib N Murshudov; Guy G Dodson; P C Moody; J P Turkenburg; A Neil Barclay; R L Brady
Crystal structure of an extracellular fragment of the rat CD4 receptor containing domains 3 and 4.
Structure (London, England : 1993) 1994;2(6):469-81.
1994: Jeremy R H Tame; Garib N Murshudov; Eleanor J Dodson; T K Neil; Guy G Dodson; C F Higgins; Anthony J Wilkinson
The structural basis of sequence-independent peptide binding by OppA protein.
Science (New York, N.Y.) 1994;264(5165):1578-81.
1994: L Brady; Guy G Dodson
Drug design. Reflections on a peptide.
Nature 1994;368(6473):692-3.
1994: D M Lawson; Andrzej M Brzozowski; Stéphane Réty; chandra verma; Guy G Dodson
Probing the nature of substrate binding in Humicola lanuginosa lipase through X-ray crystallography and intuitive modelling.
Protein engineering 1994;7(4):543-50.
1994: Urszula Derewenda; L Swenson; R Green; Y Wei; Guy G Dodson; S Yamaguchi; M J Haas; Zygmunt S Derewenda
An unusual buried polar cluster in a family of fungal lipases.
Nature structural biology 1994;1(1):36-47.
1994: N J Crowther; B Xiao; P N Jørgensen; Guy G Dodson; C N Hales
Epitope analysis of human insulin and intact proinsulin.
Protein engineering 1994;7(1):137-44.
1993: Gideon J Davies; Guy G Dodson; Roderick E Hubbard; S P Tolley; Zbigniew Dauter; Keith S Wilson; C Hjort; J M Mikkelsen; G Rasmussen; Martin Schülein
Structure and function of endoglucanase V.
Nature 1993;365(6444):362-4.
1993: V Richard; Guy G Dodson; Y Mauguen
Human deoxyhaemoglobin-2,3-diphosphoglycerate complex low-salt structure at 2.5 A resolution.
Journal of molecular biology 1993;233(2):270-4.
1993: Guy G Dodson; Eleanor J Dodson; J P Turkenburg; X Bing
Molecular recognition in insulin assembly.
Biochemical Society transactions 1993;21 ( Pt 3)(3):609-14.
1993: R L Brady; Eleanor J Dodson; Guy G Dodson; G Lange; S J Davis; A F Williams; A Neil Barclay
Crystal structure of domains 3 and 4 of rat CD4: relation to the NH2-terminal domains.
Science (New York, N.Y.) 1993;260(5110):979-83.
1993: A Hjorth; Frédéric Carrière; C Cudrey; H Wöldike; E Boel; D M Lawson; Francine Ferrato; Christian Cambillau; Guy G Dodson; Lars Thim
A structural domain (the lid) found in pancreatic lipases is absent in the guinea pig (phospho)lipase.
Biochemistry 1993;32(18):4702-7.
1992: Graham A Bentley; J Brange; Zygmunt S Derewenda; Eleanor J Dodson; Guy G Dodson; Jan Markussen; Anthony J Wilkinson; A Wollmer; B Xiao
Role of B13 Glu in insulin assembly. The hexamer structure of recombinant mutant (B13 Glu-->Gln) insulin.
Journal of molecular biology 1992;228(4):1163-76.
1992: G Davies; S Tolley; K Wilson; Martin Schülein; H F Wöldike; Guy G Dodson
Crystallization and preliminary X-ray analysis of a fungal endoglucanase I.
Journal of molecular biology 1992;228(3):970-2.
1992: R Liddington; Zygmunt S Derewenda; Eleanor J Dodson; R Hubbard; Guy G Dodson
High resolution crystal structures and comparisons of T-state deoxyhaemoglobin and two liganded T-state haemoglobins: T(alpha-oxy)haemoglobin and T(met)haemoglobin.
Journal of molecular biology 1992;228(2):551-79.
1992: Zygmunt S Derewenda; Urszula Derewenda; Guy G Dodson
The crystal and molecular structure of the Rhizomucor miehei triacylglyceride lipase at 1.9 A resolution.
Journal of molecular biology 1992;227(3):818-39.
1992: Guy G Dodson; D M Lawson; F K Winkler
Structural and evolutionary relationships in lipase mechanism and activation.
Faraday discussions 1992;(93):95-105.
1991: P Balschmidt; F B Hansen; E J Dodson; Guy G Dodson; F Korber
Structure of porcine insulin cocrystallized with clupeine Z.
Acta crystallographica. Section B, Structural science 1991;47 ( Pt 6)():975-86.
1991: H J Swift; L Brady; Zygmunt S Derewenda; Eleanor J Dodson; Guy G Dodson; J P Turkenburg; Anthony J Wilkinson
Structure and molecular model refinement of Aspergillus oryzae (TAKA) alpha-amylase: an application of the simulated-annealing method.
Acta crystallographica. Section B, Structural science 1991;47 ( Pt 4)():535-44.
1991: R L Brady; Andrzej M Brzozowski; Zygmunt S Derewenda; Eleanor J Dodson; Guy G Dodson
Solution of the structure of Aspergillus niger acid alpha-amylase by combined molecular replacement and multiple isomorphous replacement methods.
Acta crystallographica. Section B, Structural science 1991;47 ( Pt 4)():527-35.
1991: Urszula Derewenda; Zygmunt S Derewenda; Eleanor J Dodson; Guy G Dodson; X Bing; Jan Markussen
X-ray analysis of the single chain B29-A1 peptide-linked insulin molecule. A completely inactive analogue.
Journal of molecular biology 1991;220(2):425-33.
1991: Stephen John Smerdon; Guy G Dodson; Anthony J Wilkinson; Quentin H Gibson; R S Blackmore
Distal pocket polarity in ligand binding to myoglobin: structural and functional characterization of a threonine68(E11) mutant.
Biochemistry 1991;30(25):6252-60.
1991: Dale B Wigley; G J Davies; Eleanor J Dodson; A Maxwell; Guy G Dodson
Crystal structure of an N-terminal fragment of the DNA gyrase B protein.
Nature 1991;351(6328):624-9.
1991: Andrzej M Brzozowski; Urszula Derewenda; Zygmunt S Derewenda; Guy G Dodson; D M Lawson; J P Turkenburg; F Bjorkling; B Huge-Jensen; S A Patkar; Lars Thim
A model for interfacial activation in lipases from the structure of a fungal lipase-inhibitor complex.
Nature 1991;351(6326):491-4.
1991: Jozef Sevcik; E J Dodson; Guy G Dodson
Determination and restrained least-squares refinement of the structures of ribonuclease Sa and its complex with 3'-guanylic acid at 1.8 A resolution.
Acta crystallographica. Section B, Structural science 1991;47 ( Pt 2)():240-53.
1991: J Badger; M R Harris; C D Reynolds; A C Evans; Eleanor J Dodson; Guy G Dodson; A C North
Structure of the pig insulin dimer in the cubic crystal.
Acta crystallographica. Section B, Structural science 1991;47 ( Pt 1)():127-36.
1991: C P Hill; Zbigniew Dauter; Eleanor J Dodson; Guy G Dodson; M F Dunn
X-ray structure of an unusual Ca2+ site and the roles of Zn2+ and Ca2+ in the assembly, stability, and storage of the insulin hexamer.
Biochemistry 1991;30(4):917-24.
1990: E Boel; L Brady; Andrzej M Brzozowski; Zygmunt S Derewenda; Guy G Dodson; V J Jensen; Steffen Petersen; H Swift; Lars Thim; H F Woldike
Calcium binding in alpha-amylases: an X-ray diffraction study at 2.1-A resolution of two enzymes from Aspergillus.
Biochemistry 1990;29(26):6244-9.
1990: P D Hunt; S P Tolley; R J Ward; C P Hill; Guy G Dodson
Expression, purification and crystallization of penicillin G acylase from Escherichia coli ATCC 11105.
Protein engineering 1990;3(7):635-9.
1990: Stephen John Smerdon; T J Oldfield; Eleanor J Dodson; Guy G Dodson; Roderick E Hubbard; Anthony J Wilkinson
Determination of the crystal structure of recombinant pig myoglobin by molecular replacement and its refinement.
Acta crystallographica. Section B, Structural science 1990;46 ( Pt 3)():370-7.
1990: Simon J Davis; R L Brady; A Neil Barclay; K Harlos; Guy G Dodson; A F Williams
Crystallization of a soluble form of the rat T-cell surface glycoprotein CD4 complexed with Fab from the W3/25 monoclonal antibody.
Journal of molecular biology 1990;213(1):7-10.
1990: L Brady; Andrzej M Brzozowski; Zygmunt S Derewenda; Eleanor J Dodson; Guy G Dodson; S Tolley; J P Turkenburg; L Christiansen; B Huge-Jensen; L Norskov
A serine protease triad forms the catalytic centre of a triacylglycerol lipase.
Nature 1990;343(6260):767-70.
1990: Guy G Dodson; V R Richard; S P Tolley; D A Waller; Roy E. Weber
Crystallization of the rainbow trout (Salmo gairdneri) haemoglobin IV.
Journal of molecular biology 1990;211(4):691-2.
1990: Zygmunt S Derewenda; Guy G Dodson; P Emsley; D Harris; K Nagai; M Perutz; J P Renaud; J P Reynaud
Stereochemistry of carbon monoxide binding to normal human adult and Cowtown haemoglobins.
Journal of molecular biology 1990;211(3):515-9.
1989: Urszula Derewenda; Zygmunt S Derewenda; Eleanor J Dodson; Guy G Dodson; C D Reynolds; G D Smith; C Sparks; D Swenson
Phenol stabilizes more helix in a new symmetrical zinc insulin hexamer.
Nature 1989;338(6216):594-6.
1988: Guy G Dodson; Roderick E Hubbard; T J Oldfield; Stephen John Smerdon; Anthony J Wilkinson
Apomyoglobin as a molecular recognition surface: expression, reconstitution and crystallization of recombinant porcine myoglobin in Escherichia coli.
Protein engineering 1988;2(3):233-7.
1988: R Liddington; Zygmunt S Derewenda; Guy G Dodson; D Harris
Structure of the liganded T state of haemoglobin identifies the origin of cooperative oxygen binding.
Nature 1988;331(6158):725-8.
1984: Andrzej M Brzozowski; Zygmunt S Derewenda; Eleanor J Dodson; Guy G Dodson; M Grabowski; R Liddington; T Skarzyński; D Vallely
Bonding of molecular oxygen to T state human haemoglobin.
Nature 1984;307(5946):74-6.
1983: Dorothy Hodgkin; Eleanor J Dodson; Guy G Dodson; C Reynolds
Insulin.
Biochemical Society transactions 1983;11(4):411-7.
1982: Y Mauguen; R W Hartley; E J Dodson; Guy G Dodson; G Bricogne; C Chothia; A Jack
Molecular structure of a new family of ribonucleases.
Nature 1982;297(5862):162-4.
1981: John F Cutfield; Sue M Cutfield; E Dodson; Guy G Dodson; Dorothy Hodgkin; C Reynolds
Evidence concerning insulin activity from the structure of a cross-linked derivative.
Hoppe-Seyler's Zeitschrift für physiologische Chemie 1981;362(6):755-61.