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Chris Doe
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Research Profile (preview)
Chemicals & Drugs
Living Beings
Anatomy
Concepts & Ideas
Physiology
Genes & Molecular Sequences
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Network (preview)
6
Siller, Karsten
5
Fuerstenberg, Sal
4
Cabernard, Clemens
4
Albertson, Roger
4
Prehoda, Kenneth
4
Siegrist, Sarah
4
Pearson, Bret
4
Rolls, Melissa
4
Technau, Gerhard
4
Lee, Cheng Yu
3
Freeman, Marc
3
Von Ohlen, Tonia
3
Broadus, J
3
Skeath, JB
3
Bossing, Torsten
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All Publications
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2009: Marcette Jana; Hood Iris V; Johnston Christopher A; Doe Chris Q; Prehoda Kenneth E
Allosteric control of regulated scaffolding in membrane-associated guanylate kinases.
Biochemistry 2009;48(42):10014-9.
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2009: Johnston Christopher A; Hirono Keiko; Prehoda Kenneth E; Doe Chris Q
Identification of an Aurora-A/PinsLINKER/Dlg spindle orientation pathway using induced cell polarity in S2 cells.
Cell 2009;138(6):1150-63.
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2009: Cabernard Clemens; Doe Chris Q
Apical/basal spindle orientation is required for neuroblast homeostasis and neuronal differentiation in Drosophila.
Developmental cell 2009;17(1):134-41.
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2009: Miller Michael R; Robinson Kristin J; Cleary Michael D; Doe Chris Q
TU-tagging: cell type-specific RNA isolation from intact complex tissues.
Nature methods 2009;6(6):439-41.
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2009: Chabu Chiswili; Doe Chris Q
Twins/PP2A regulates aPKC to control neuroblast cell polarity and self-renewal.
Developmental biology 2009;330(2):399-405.
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2009: Siller Karsten H; Doe Chris Q
Spindle orientation during asymmetric cell division.
Nature cell biology 2009;11(4):365-74.
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2008: Tran Khoa D; Doe Chris Q
Pdm and Castor close successive temporal identity windows in the NB3-1 lineage.
Development (Cambridge, England) 2008;135(21):3491-9.
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2008: Chabu Chiswili; Doe Chris Q
Dap160/intersectin binds and activates aPKC to regulate cell polarity and cell cycle progression.
Development (Cambridge, England) 2008;135(16):2739-46.
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2008: Boone Jason Q; Doe Chris Q
Identification of Drosophila type II neuroblast lineages containing transit amplifying ganglion mother cells.
Developmental neurobiology 2008;68(9):1185-95.
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2008: Pfeiffer Barret D; Jenett Arnim; Hammonds Ann S; Ngo Teri-T B; Misra Sima; Murphy Christine; Scully Audra; Carlson Joseph W; Wan Kenneth H; Laverty Todd R; Mungall Chris; Svirskas Rob; Kadonaga James T; Doe Chris Q; Eisen Michael B; Celniker Susan E; Rubin Gerald M
Tools for neuroanatomy and neurogenetics in Drosophila.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(28):9715-20.
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2008: Siller Karsten H; Doe Chris Q
Lis1/dynactin regulates metaphase spindle orientation in Drosophila neuroblasts.
Developmental biology 2008;319(1):1-9.
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2008: Doe Chris Q
Neural stem cells: balancing self-renewal with differentiation.
Development (Cambridge, England) 2008;135(9):1575-87.
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2008: Zhu Changqi C; Boone Jason Q; Jensen Philip A; Hanna Scott; Podemski Lynn; Locke John; Doe Chris Q; O'Connor Michael B
Drosophila Activin- and the Activin-like product Dawdle function redundantly to regulate proliferation in the larval brain.
Development (Cambridge, England) 2008;135(3):513-21.
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2007: Nipper Rick W; Siller Karsten H; Smith Nicholas R; Doe Chris Q; Prehoda Kenneth E
Galphai generates multiple Pins activation states to link cortical polarity and spindle orientation in Drosophila neuroblasts.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(36):14306-11.
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2007: Atwood Scott X; Chabu Chiswili; Penkert Rhiannon R; Doe Chris Q; Prehoda Kenneth E
Cdc42 acts downstream of Bazooka to regulate neuroblast polarity through Par-6 aPKC.
Journal of cell science 2007;120(Pt 18):3200-6.
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2007: Cabernard Clemens; Doe Chris Q
Stem cell self-renewal: centrosomes on the move.
Current biology : CB 2007;17(12):R465-7.
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2007: Siegrist Sarah E; Doe Chris Q
Microtubule-induced cortical cell polarity.
Genes & development 2007;21(5):483-96.
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2007: Rolls Melissa M; Satoh Daisuke; Clyne Peter J; Henner Astra L; Uemura Tadashi; Doe Chris Q
Polarity and intracellular compartmentalization of Drosophila neurons.
Neural development 2007;2():7.
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2007: Egger Boris; Boone Jason Q; Stevens Naomi R; Brand Andrea H; Doe Chris Q
Regulation of spindle orientation and neural stem cell fate in the Drosophila optic lobe.
Neural development 2007;2():1.
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2006: Lee Cheng-Yu; Andersen Ryan O; Cabernard Clemens; Manning Laurina; Tran Khoa D; Lanskey Marcus J; Bashirullah Arash; Doe Chris Q
Drosophila Aurora-A kinase inhibits neuroblast self-renewal by regulating aPKC/Numb cortical polarity and spindle orientation.
Genes & development 2006;20(24):3464-74.
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2006: Doe Chris Q
Chinmo and neuroblast temporal identity.
Cell 2006;127(2):254-6.
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2006: Grosskortenhaus Ruth; Robinson Kristin J; Doe Chris Q
Pdm and Castor specify late-born motor neuron identity in the NB7-1 lineage.
Genes & development 2006;20(18):2618-27.
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2006: Siller Karsten H; Cabernard Clemens; Doe Chris Q
The NuMA-related Mud protein binds Pins and regulates spindle orientation in Drosophila neuroblasts.
Nature cell biology 2006;8(6):594-600.
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2006: Lee Cheng-Yu; Wilkinson Brian D; Siegrist Sarah E; Wharton Robin P; Doe Chris Q
Brat is a Miranda cargo protein that promotes neuronal differentiation and inhibits neuroblast self-renewal.
Developmental cell 2006;10(4):441-9.
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2006: Layden Michael J; Odden Joanne P; Schmid Aloisia; Garces Alain; Thor Stefan; Doe Chris Q
Zfh1, a somatic motor neuron transcription factor, regulates axon exit from the CNS.
Developmental biology 2006;291(2):253-63.
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2006: Cleary Michael D; Doe Chris Q
Regulation of neuroblast competence: multiple temporal identity factors specify distinct neuronal fates within a single early competence window.
Genes & development 2006;20(4):429-34.
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2006: Siegrist Sarah E; Doe Chris Q
Extrinsic cues orient the cell division axis in Drosophila embryonic neuroblasts.
Development (Cambridge, England) 2006;133(3):529-36.
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2006: Lee Cheng-Yu; Robinson Kristin J; Doe Chris Q
Lgl, Pins and aPKC regulate neuroblast self-renewal versus differentiation.
Nature 2006;439(7076):594-8.
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2005: Siegrist Sarah E; Doe Chris Q
Microtubule-induced Pins/Galphai cortical polarity in Drosophila neuroblasts.
Cell 2005;123(7):1323-35.
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2005: Siller Karsten H; Serr Madeline; Steward Ruth; Hays Tom S; Doe Chris Q
Live imaging of Drosophila brain neuroblasts reveals a role for Lis1/dynactin in spindle assembly and mitotic checkpoint control.
Molecular biology of the cell 2005;16(11):5127-40.
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2005: Armstrong Jennifer A; Sperling Adam S; Deuring Renate; Manning Laurina; Moseley Sarah L; Papoulas Ophelia; Piatek Caroline I; Doe Chris Q; Tamkun John W
Genetic screens for enhancers of brahma reveal functional interactions between the BRM chromatin-remodeling complex and the delta-notch signal transduction pathway in Drosophila.
Genetics 2005;170(4):1761-74.
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2005: Grosskortenhaus Ruth; Pearson Bret J; Marusich Amanda; Doe Chris Q
Regulation of temporal identity transitions in Drosophila neuroblasts.
Developmental cell 2005;8(2):193-202.
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2005: Karcavich Rachel; Doe Chris Q
Drosophila neuroblast 7-3 cell lineage: a model system for studying programmed cell death, Notch/Numb signaling, and sequential specification of ganglion mother cell identity.
The Journal of comparative neurology 2005;481(3):240-51.
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2004: Rolls Melissa M; Doe Chris Q
Baz, Par-6 and aPKC are not required for axon or dendrite specification in Drosophila.
Nature neuroscience 2004;7(12):1293-5.
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2004: Albertson Roger; Chabu Chiswili; Sheehan Amy; Doe Chris Q
Scribble protein domain mapping reveals a multistep localization mechanism and domains necessary for establishing cortical polarity.
Journal of cell science 2004;117(Pt 25):6061-70.
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2004: Cheesman Sarah E; Layden Michael J; Von Ohlen Tonia; Doe Chris Q; Eisen Judith S
Zebrafish and fly Nkx6 proteins have similar CNS expression patterns and regulate motoneuron formation.
Development (Cambridge, England) 2004;131(21):5221-32.
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2004: Isshiki Takako; Doe Chris Q
Maintaining youth in Drosophila neural progenitors.
Cell cycle (Georgetown, Tex.) 2004;3(3):296-9.
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2004: Irion Uwe; Leptin Maria; Siller Karsten; Fuerstenberg Sal; Cai Yu; Doe Chris Q; Chia William; Yang Xiaohang
Abstrakt, a DEAD box protein, regulates Insc levels and asymmetric division of neural and mesodermal progenitors.
Current biology : CB 2004;14(2):138-44.
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2004: Pearson Bret J; Doe Chris Q
Specification of temporal identity in the developing nervous system.
Annual review of cell and developmental biology 2004;20():619-47.
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2003: Rolls Melissa M; Albertson Roger; Shih Hsin-Pei; Lee Cheng-Yu; Doe Chris Q
Drosophila aPKC regulates cell polarity and cell proliferation in neuroblasts and epithelia.
The Journal of cell biology 2003;163(5):1089-98.
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2003: McDonald Jocelyn A; Fujioka Miki; Odden Joanne P; Jaynes James B; Doe Chris Q
Specification of motoneuron fate in Drosophila: integration of positive and negative transcription factor inputs by a minimal eve enhancer.
Journal of neurobiology 2003;57(2):193-203.
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2003: Pearson Bret J; Doe Chris Q
Regulation of neuroblast competence in Drosophila.
Nature 2003;425(6958):624-8.
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2003: Freeman Marc R; Delrow Jeffrey; Kim Junhyong; Johnson Eric; Doe Chris Q
Unwrapping glial biology: Gcm target genes regulating glial development, diversification, and function.
Neuron 2003;38(4):567-80.
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2003: Rolls Melissa M; Doe Chris Q
Cell polarity: From embryo to axon.
Nature 2003;421(6926):905-6.
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2003: Albertson Roger; Doe Chris Q
Dlg, Scrib and Lgl regulate neuroblast cell size and mitotic spindle asymmetry.
Nature cell biology 2003;5(2):166-70.
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2002: Ryter Jodi M; Doe Chris Q; Matthews Brian W
Structure of the DNA binding region of prospero reveals a novel homeo-prospero domain.
Structure (London, England : 1993) 2002;10(11):1541-9.
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2002: Odden Joanne P; Holbrook Scott; Doe Chris Q
Drosophila HB9 is expressed in a subset of motoneurons and interneurons, where it regulates gene expression and axon pathfinding.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(21):9143-9.
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2001: Zelhof A C; Bao H; Hardy R W; Razzaq A; Zhang B; Doe C Q
Drosophila Amphiphysin is implicated in protein localization and membrane morphogenesis but not in synaptic vesicle endocytosis.
Development (Cambridge, England) 2001;128(24):5005-15.
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2001: Freeman M R; Doe C Q
Moving muscle. Jeb signaling in Drosophila.
Developmental cell 2001;1(5):587-8.
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2001: Freeman M R; Doe C Q
Asymmetric Prospero localization is required to generate mixed neuronal/glial lineages in the Drosophila CNS.
Development (Cambridge, England) 2001;128(20):4103-12.
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2001: Isshiki T; Pearson B; Holbrook S; Doe C Q
Drosophila neuroblasts sequentially express transcription factors which specify the temporal identity of their neuronal progeny.
Cell 2001;106(4):511-21.
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2001: Doe C Q; Bowerman B
Asymmetric cell division: fly neuroblast meets worm zygote.
Current opinion in cell biology 2001;13(1):68-75.
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2001: Doe C Q
Cell polarity: the PARty expands.
Nature cell biology 2001;3(1):E7-9.
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2000: Peng C Y; Manning L; Albertson R; Doe C Q
The tumour-suppressor genes lgl and dlg regulate basal protein targeting in Drosophila neuroblasts.
Nature 2000;408(6812):596-600.
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2000: von Ohlen T; Doe C Q
Convergence of dorsal, dpp, and egfr signaling pathways subdivides the drosophila neuroectoderm into three dorsal-ventral columns.
Developmental biology 2000;224(2):362-72.
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1999: Schmid A; Chiba A; Doe C Q
Clonal analysis of Drosophila embryonic neuroblasts: neural cell types, axon projections and muscle targets.
Development (Cambridge, England) 1999;126(21):4653-89.
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1999: Manning L; Doe C Q
Prospero distinguishes sibling cell fate without asymmetric localization in the Drosophila adult external sense organ lineage.
Development (Cambridge, England) 1999;126(10):2063-71.
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1998: Fuerstenberg S; Peng C Y; Alvarez-Ortiz P; Hor T; Doe C Q
Identification of Miranda protein domains regulating asymmetric cortical localization, cargo binding, and cortical release.
Molecular and cellular neurosciences 1998;12(6):325-39.
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1998: Srinivasan S; Peng C Y; Nair S; Skeath J B; Spana E P; Doe C Q
Biochemical analysis of ++Prospero protein during asymmetric cell division: cortical Prospero is highly phosphorylated relative to nuclear Prospero.
Developmental biology 1998;204(2):478-87.
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1998: McDonald J A; Holbrook S; Isshiki T; Weiss J; Doe C Q; Mellerick D M
Dorsoventral patterning in the Drosophila central nervous system: the vnd homeobox gene specifies ventral column identity.
Genes & development 1998;12(22):3603-12.
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1998: Weiss J B; Von Ohlen T; Mellerick D M; Dressler G; Doe C Q; Scott M P
Dorsoventral patterning in the Drosophila central nervous system: the intermediate neuroblasts defective homeobox gene specifies intermediate column identity.
Genes & development 1998;12(22):3591-602.
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1998: Doe C Q; Fuerstenberg S; Peng C Y
Neural stem cells: from fly to vertebrates.
Journal of neurobiology 1998;36(2):111-27.
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1998: Skeath J B; Doe C Q
Sanpodo and Notch act in opposition to Numb to distinguish sibling neuron fates in the Drosophila CNS.
Development (Cambridge, England) 1998;125(10):1857-65.
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1998: Broadus J; Fuerstenberg S; Doe C Q
Staufen-dependent localization of prospero mRNA contributes to neuroblast daughter-cell fate.
Nature 1998;391(6669):792-5.
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1998: Fuerstenberg S; Broadus J; Doe C Q
Asymmetry and cell fate in the Drosophila embryonic CNS.
The International journal of developmental biology 1998;42(3):379-83.
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1997: Ikeshima-Kataoka H; Skeath J B; Nabeshima Y; Doe C Q; Matsuzaki F
Miranda directs Prospero to a daughter cell during Drosophila asymmetric divisions.
Nature 1997;390(6660):625-9.
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1997: Broadus J; Doe C Q
Extrinsic cues, intrinsic cues and microfilaments regulate asymmetric protein localization in Drosophila neuroblasts.
Current biology : CB 1997;7(11):827-35.
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1997: McDonald J A; Doe C Q
Establishing neuroblast-specific gene expression in the Drosophila CNS: huckebein is activated by Wingless and Hedgehog and repressed by Engrailed and Gooseberry.
Development (Cambridge, England) 1997;124(5):1079-87.
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1996: Doe C Q
Asymmetric cell division and neurogenesis.
Current opinion in genetics & development 1996;6(5):562-6.
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1996: Bossing T; Udolph G; Doe C Q; Technau G M
The embryonic central nervous system lineages of Drosophila melanogaster. I. Neuroblast lineages derived from the ventral half of the neuroectoderm.
Developmental biology 1996;179(1):41-64.
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1996: Skeath J B; Doe C Q
The achaete-scute complex proneural genes contribute to neural precursor specification in the Drosophila CNS.
Current biology : CB 1996;6(9):1146-52.
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1996: Doe C Q
Spindle orientation and asymmetric localization in Drosophila: both inscuteable?
Cell 1996;86(5):695-7.
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1996: Spana E P; Doe C Q
Numb antagonizes Notch signaling to specify sibling neuron cell fates.
Neuron 1996;17(1):21-6.
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1996: Bossing T; Technau G M; Doe C Q
huckebein is required for glial development and axon pathfinding in the neuroblast 1-1 and neuroblast 2-2 lineages in the Drosophila central nervous system.
Mechanisms of development 1996;55(1):53-64.
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1996: Doe C Q; Skeath J B
Neurogenesis in the insect central nervous system.
Current opinion in neurobiology 1996;6(1):18-24.
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1996: Lundell M J; Chu-LaGraff Q; Doe C Q; Hirsh J
The engrailed and huckebein genes are essential for development of serotonin neurons in the Drosophila CNS.
Molecular and cellular neurosciences 1996;7(1):46-61.
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1995: Broadus J; Doe C Q
Evolution of neuroblast identity: seven-up and prospero expression reveal homologous and divergent neuroblast fates in Drosophila and Schistocerca.
Development (Cambridge, England) 1995;121(12):3989-96.
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1995: Broadus J; Skeath J B; Spana E P; Bossing T; Technau G; Doe C Q
New neuroblast markers and the origin of the aCC/pCC neurons in the Drosophila central nervous system.
Mechanisms of development 1995;53(3):393-402.
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1995: Spana E P; Kopczynski C; Goodman C S; Doe C Q
Asymmetric localization of numb autonomously determines sibling neuron identity in the Drosophila CNS.
Development (Cambridge, England) 1995;121(11):3489-94.
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1995: Doe C Q; Spana E P
A collection of cortical crescents: asymmetric protein localization in CNS precursor cells.
Neuron 1995;15(5):991-5.
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1995: Chu-LaGraff Q; Schmid A; Leidel J; Brönner G; Jäckle H; Doe C Q
huckebein specifies aspects of CNS precursor identity required for motoneuron axon pathfinding.
Neuron 1995;15(5):1041-51.
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1995: Cui X; Doe C Q
The role of the cell cycle and cytokinesis in regulating neuroblast sublineage gene expression in the Drosophila CNS.
Development (Cambridge, England) 1995;121(10):3233-43.
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1995: Spana E P; Doe C Q
The prospero transcription factor is asymmetrically localized to the cell cortex during neuroblast mitosis in Drosophila.
Development (Cambridge, England) 1995;121(10):3187-95.
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1995: Skeath J B; Zhang Y; Holmgren R; Carroll S B; Doe C Q
Specification of neuroblast identity in the Drosophila embryonic central nervous system by gooseberry-distal.
Nature 1995;376(6539):427-30.
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1994: Brönner G; Chu-LaGraff Q; Doe C Q; Cohen B; Weigel D; Taubert H; Jäckle H
Sp1/egr-like zinc-finger protein required for endoderm specification and germ-layer formation in Drosophila.
Nature 1994;369(6482):664-8.
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1993: Doe C Q; Technau G M
Identification and cell lineage of individual neural precursors in the Drosophila CNS.
Trends in neurosciences 1993;16(12):510-4.
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1993: Oliver G; Sosa-Pineda B; Geisendorf S; Spana E P; Doe C Q; Gruss P
Prox 1, a prospero-related homeobox gene expressed during mouse development.
Mechanisms of development 1993;44(1):3-16.
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1993: Chu-LaGraff Q; Doe C Q
Neuroblast specification and formation regulated by wingless in the Drosophila CNS.
Science (New York, N.Y.) 1993;261(5128):1594-7.
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1992: Cui X; Doe C Q
ming is expressed in neuroblast sublineages and regulates gene expression in the Drosophila central nervous system.
Development (Cambridge, England) 1992;116(4):943-52.
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1992: Doe C Q
Molecular markers for identified neuroblasts and ganglion mother cells in the Drosophila central nervous system.
Development (Cambridge, England) 1992;116(4):855-63.
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1991: Doe C Q; Chu-LaGraff Q; Wright D M; Scott M P
The prospero gene specifies cell fates in the Drosophila central nervous system.
Cell 1991;65(3):451-64.
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1991: Chu-Lagraff Q; Wright D M; McNeil L K; Doe C Q
The prospero gene encodes a divergent homeodomain protein that controls neuronal identity in Drosophila.
Development (Cambridge, England) 1991;Suppl 2():79-85.
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1990: Doe C Q; Smouse D T
The origins of cell diversity in the insect central nervous system.
Seminars in cell biology 1990;1(3):211-8.
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1988: Doe C Q; Hiromi Y; Gehring W J; Goodman C S
Expression and function of the segmentation gene fushi tarazu during Drosophila neurogenesis.
Science (New York, N.Y.) 1988;239(4836):170-5.
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