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Walter Doerfler

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Co-Publications
Name
22
Schmitz, Birgit
13
Renz, D
10
Schubbert, R
10
Kochanek, Stefan
9
Heller, H
9
Remus, Ralph
8
Schröer, J
8
Hösel, Marianna
7
Webb, Dennis
6
Zeschnigk, Michael
6
Hohlweg, Urte
6
Kämmer, C
5
Hilger-Eversheim, Kristina
5
Naumann, Frauke
4
Schumacher, Axel

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Publications

TOP 3
Naumann Anja; Hochstein Norbert; Weber Stefanie; Fanning Ellen; Doerfler Walter
A distinct DNA-methylation boundary in the 5'- upstream sequence of the FMR1 promoter binds nuclear proteins and is lost in fragile X syndrome.
Doerfler Walter
In pursuit of the first recognized epigenetic signal--DNA methylation: a 1976 to 2008 synopsis.
Hochstein Norbert; Webb Dennis; Hösel Marianna; Seidel Werner; Auerochs Sabrina; Doerfler Walter
Human CAR gene expression in nonpermissive hamster cells boosts entry of type 12 adenovirions and nuclear import of viral DNA.

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All Publications

2009: Naumann Anja; Hochstein Norbert; Weber Stefanie; Fanning Ellen; Doerfler Walter
A distinct DNA-methylation boundary in the 5'- upstream sequence of the FMR1 promoter binds nuclear proteins and is lost in fragile X syndrome.
American journal of human genetics 2009;85(5):606-16.
2008: Doerfler Walter
In pursuit of the first recognized epigenetic signal--DNA methylation: a 1976 to 2008 synopsis.
Epigenetics : official journal of the DNA Methylation Society 2008;3(3):125-33.
2008: Hochstein Norbert; Webb Dennis; Hösel Marianna; Seidel Werner; Auerochs Sabrina; Doerfler Walter
Human CAR gene expression in nonpermissive hamster cells boosts entry of type 12 adenovirions and nuclear import of viral DNA.
Journal of virology 2008;82(8):4159-63.
2007: Hochstein Norbert; Muiznieks Indrikis; Mangel Laurence; Brondke Holger; Doerfler Walter
Epigenetic status of an adenovirus type 12 transgenome upon long-term cultivation in hamster cells.
Journal of virology 2007;81(10):5349-61.
2007: Brondke H; Schmitz B; Doerfler W
Nucleotide sequence comparisons between several strains and isolates of human cytomegalovirus reveal alternate start codon usage.
Archives of virology 2007;152(11):2035-46.
2006: Doerfler W
De novo methylation, long-term promoter silencing, methylation patterns in the human genome, and consequences of foreign DNA insertion.
Current topics in microbiology and immunology 2006;301():125-75.
2006: Doerfler W
The almost-forgotten fifth nucleotide in DNA: an introduction.
Current topics in microbiology and immunology 2006;301():3-18.
2005: Remus Ralph; Kanzaki Akio; Yawata Ayumi; Wada Hideho; Nakanishi Hidekazu; Sugihara Takashi; Zeschnigk Michael; Zuther Ines; Schmitz Birgit; Naumann Frauke; Doerfler Walter; Yawata Yoshihito
Relationships between DNA methylation and expression in erythrocyte membrane protein (band 3, protein 4.2, and beta-spectrin) genes during human erythroid development and differentiation.
International journal of hematology 2005;82(5):422-9.
2005: Remus Ralph; Kanzaki Akio; Yawata Ayumi; Nakanishi Hidekazu; Wada Hideho; Sugihara Takashi; Zeschnigk Michael; Zuther Ines; Schmitz Birgit; Naumann Frauke; Doerfler Walter; Yawata Yoshihito
DNA methylation in promoter regions of red cell membrane protein genes in healthy individuals and patients with hereditary membrane disorders.
International journal of hematology 2005;81(5):385-95.
2005: Doerfler W
On the biological significance of DNA methylation.
Biochemistry. Biokhimii?a 2005;70(5):505-24.
2005: Dorn Andreas; Zhao Hongxing; Granberg Frederik; Hösel Marianna; Webb Dennis; Svensson Catharina; Pettersson Ulf; Doerfler Walter
Identification of specific cellular genes up-regulated late in adenovirus type 12 infection.
Journal of virology 2005;79(4):2404-12.
2004: Wronka G; Bernardi G; Doerfler W
Localization of integrated adenovirus DNA in the hamster genome.
Cellular and molecular life sciences : CMLS 2004;61(23):2983-90.
2004: Miyazono F; Metzger R; Warnecke-Eberz U; Baldus S E; Brabender J; Bollschweiler E; Doerfler W; Mueller R P; Dienes H P; Aikou T; Hoelscher A H; Schneider P M
Quantitative c-erbB-2 but not c-erbB-1 mRNA expression is a promising marker to predict minor histopathologic response to neoadjuvant radiochemotherapy in oesophageal cancer.
British journal of cancer 2004;91(4):666-72.
2004: Mende Ylva; Schneider Paul M; Baldus Stephan E; Doerfler Walter
PCR-screening of human esophageal and bronchial cancers reveals absence of adenoviral DNA sequences.
Virus research 2004;104(1):81-5.
2004: Warnecke-Eberz Ute; Metzger Ralf; Miyazono Futoshi; Baldus Stephan E; Neiss Susanne; Brabender Jan; Schaefer Hartmut; Doerfler Walter; Bollschweiler Elfriede; Dienes Hans P; Mueller Rolf P; Danenberg Peter V; Hoelscher Arnulf H; Schneider Paul M
High specificity of quantitative excision repair cross-complementing 1 messenger RNA expression for prediction of minor histopathological response to neoadjuvant radiochemotherapy in esophageal cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(11):3794-9.
2004: Naumann Frauke; Remus Ralph; Schmitz Birgit; Doerfler Walter
Gene structure and expression of the 5'-(CGG)(n)-3'-binding protein (CGGBP1).
Genomics 2004;83(1):106-18.
2004: Schumacher Axel; Doerfler Walter
Influence of in vitro manipulation on the stability of methylation patterns in the Snurf/Snrpn-imprinting region in mouse embryonic stem cells.
Nucleic acids research 2004;32(4):1566-76.
2004: Hohlweg U; Dorn A; Hösel M; Webb D; Buettner R; Doerfler W
Tumorigenesis by adenovirus type 12 in newborn Syrian hamsters.
Current topics in microbiology and immunology 2004;273():215-44.
2003: Hohlweg Urte; Hösel Marianna; Dorn Andreas; Webb Dennis; Hilger-Eversheim Kristina; Remus Ralph; Schmitz Birgit; Buettner Reinhold; Schramme Anja; Corzilius Lars; Niemann Anke; Doerfler Walter
Intraperitoneal dissemination of Ad12-induced undifferentiated neuroectodermal hamster tumors: de novo methylation and transcription patterns of integrated viral and of cellular genes.
Virus research 2003;98(1):45-56.
2003: Palka-Santini M; Schwarz-Herzke B; Hösel M; Renz D; Auerochs S; Brondke H; Doerfler W
The gastrointestinal tract as the portal of entry for foreign macromolecules: fate of DNA and proteins.
Molecular genetics and genomics : MGG 2003;270(3):201-15.
2003: Schumacher Axel; Arnhold Stefan; Addicks Klaus; Doerfler Walter
Staurosporine is a potent activator of neuronal, glial, and "CNS stem cell-like" neurosphere differentiation in murine embryonic stem cells.
Molecular and cellular neurosciences 2003;23(4):669-80.
2003: Hösel M; Webb D; Schröer J; Doerfler W
The abortive infection of Syrian hamster cells with human adenovirus type 12.
Current topics in microbiology and immunology 2003;272():415-40.
2002: Wronka Gerd; Fechteler Katja; Schmitz Birgit; Doerfler Walter
Integrative recombination between adenovirus type 12 DNA and mammalian DNA in a cell-free system: joining by short sequence homologies.
Virus research 2002;90(1-2):225-42.
2002: Palka L; Palka-Santini M E; Chambon S; Renz D; Maurer P; Doerfler W
Amyloglucosidase suppresses interference by glycogen in the quantification of DNA using the Hoechst 33258 dye.
BioTechniques 2002;32(6):1250,1252,1254,1256.
2001: Hösel M; Schröer J; Webb D; Jaroshevskaja E; Doerfler W
Cellular and early viral factors in the interaction of adenovirus type 12 with hamster cells: the abortive response.
Virus research 2001;81(1-2):1-16.
2001: Hösel M; Webb D; Schröer J; Schmitz B; Doerfler W
Overexpression of the adenovirus type 12 (Ad12) pTP or E1A gene facilitates Ad12 DNA replication in nonpermissive BHK21 hamster cells.
Journal of virology 2001;75(21):10041-53.
2001: Doerfler W; Hohlweg U; Müller K; Remus R; Heller H; Hertz J
Foreign DNA integration--perturbations of the genome--oncogenesis.
Annals of the New York Academy of Sciences 2001;945():276-88.
2001: Hohlweg U; Doerfler W
On the fate of plant or other foreign genes upon the uptake in food or after intramuscular injection in mice.
Molecular genetics and genomics : MGG 2001;265(2):225-33.
2001: Müller K; Heller H; Doerfler W
Foreign DNA integration. Genome-wide perturbations of methylation and transcription in the recipient genomes.
The Journal of biological chemistry 2001;276(17):14271-8.
2001: Doerfler W; Remus R; Müller K; Heller H; Hohlweg U; Schubbert R
The fate of foreign DNA in mammalian cells and organisms.
Developments in biologicals 2001;106():89-97; discussion 143-60.
2000: Schumacher A; Koetsier P A; Hertz J; Doerfler W
Epigenetic and genotype-specific effects on the stability of de novo imposed methylation patterns in transgenic mice.
The Journal of biological chemistry 2000;275(48):37915-21.
2000: Backes M; Genç B; Schreck J; Doerfler W; Lehmkuhl G; von Gontard A
Cognitive and behavioral profile of fragile X boys: correlations to molecular data.
American journal of medical genetics 2000;95(2):150-6.
2000: Munnes M; Fanaei S; Schmitz B; Muiznieks I; Holschneider A M; Doerfler W
Familial form of hirschsprung disease: nucleotide sequence studies reveal point mutations in the RET proto-oncogene in two of six families but not in other candidate genes.
American journal of medical genetics 2000;94(1):19-27.
2000: Genç B; Müller-Hartmann H; Zeschnigk M; Deissler H; Schmitz B; Majewski F; von Gontard A; Doerfler W
Methylation mosaicism of 5'-(CGG)(n)-3' repeats in fragile X, premutation and normal individuals.
Nucleic acids research 2000;28(10):2141-52.
2000: Müller-Hartmann H; Deissler H; Naumann F; Schmitz B; Schröer J; Doerfler W
The human 20-kDa 5'-(CGG)(n)-3'-binding protein is targeted to the nucleus and affects the activity of the FMR1 promoter.
The Journal of biological chemistry 2000;275(9):6447-52.
2000: Yawata Y; Kanzaki A; Yawata A; Doerfler W; Ozcan R; Eber S W
Characteristic features of the genotype and phenotype of hereditary spherocytosis in the Japanese population.
International journal of hematology 2000;71(2):118-35.
1999: Hertz J M; Schell G; Doerfler W
Factors affecting de novo methylation of foreign DNA in mouse embryonic stem cells.
The Journal of biological chemistry 1999;274(34):24232-40.
1999: Remus R; Kämmer C; Heller H; Schmitz B; Schell G; Doerfler W
Insertion of foreign DNA into an established mammalian genome can alter the methylation of cellular DNA sequences.
Journal of virology 1999;73(2):1010-22.
1999: Pfeffer A; Schubbert R; Orend G; Hilger-Eversheim K; Doerfler W
Integrated viral genomes can be lost from adenovirus type 12-induced hamster tumor cells in a clone-specific, multistep process with retention of the oncogenic phenotype.
Virus research 1999;59(1):113-27.
1998: Munnes M; Patrone G; Schmitz B; Romeo G; Doerfler W
A 5'-CG-3'-rich region in the promoter of the transcriptionally frequently silenced RET protooncogene lacks methylated cytidine residues.
Oncogene 1998;17(20):2573-83.
1998: Mangel L; Ternes T; Schmitz B; Doerfler W
New 5'-(CGG)n-3' repeats in the human genome.
The Journal of biological chemistry 1998;273(46):30466-71.
1998: Schubbert R; Hohlweg U; Renz D; Doerfler W
On the fate of orally ingested foreign DNA in mice: chromosomal association and placental transmission to the fetus.
Molecular & general genetics : MGG 1998;259(6):569-76.
1998: Schumacher A; Buiting K; Zeschnigk M; Doerfler W; Horsthemke B
Methylation analysis of the PWS/AS region does not support an enhancer-competition model.
Nature genetics 1998;19(4):324-5.
1998: Doerfler W; Schubbert R
[How dangerous is genetically engineered food]
Wiener klinische Wochenschrift 1998;110(11):411.
1998: Muiznieks I; Doerfler W
DNA fragments with specific nucleotide sequences in their single-stranded termini exhibit unusual electrophoretic mobilities.
Nucleic acids research 1998;26(8):1899-905.
1998: Doerfler W; Schubbert R
Uptake of foreign DNA from the environment: the gastrointestinal tract and the placenta as portals of entry.
Wiener klinische Wochenschrift 1998;110(2):40-4.
1998: Doerfler W; Schubbert R; Heller H; Hertz J; Remus R; Schröer J; Kämmer C; Hilger-Eversheim K; Gerhardt U; Schmitz B; Renz D; Schell G
Foreign DNA in mammalian systems.
APMIS. Supplementum 1998;84():62-8.
1997: Schröer J; Hölker I; Doerfler W
Adenovirus type 12 DNA firmly associates with mammalian chromosomes early after virus infection or after DNA transfer by the addition of DNA to the cell culture medium.
Journal of virology 1997;71(10):7923-32.
1997: Doerfler W; Schubbert R; Heller H; Kämmer C; Hilger-Eversheim K; Knoblauch M; Remus R
Integration of foreign DNA and its consequences in mammalian systems.
Trends in biotechnology 1997;15(8):297-301.
1997: Hilger-Eversheim K; Doerfler W
Clonal origin of adenovirus type 12-induced hamster tumors: nonspecific chromosomal integration sites of viral DNA.
Cancer research 1997;57(14):3001-9.
1997: Deissler H; Wilm M; Genç B; Schmitz B; Ternes T; Naumann F; Mann M; Doerfler W
Rapid protein sequencing by tandem mass spectrometry and cDNA cloning of p20-CGGBP. A novel protein that binds to the unstable triplet repeat 5'-d(CGG)n-3' in the human FMR1 gene.
The Journal of biological chemistry 1997;272(27):16761-8.
1997: Zeschnigk M; Lich C; Buiting K; Doerfler W; Horsthemke B
A single-tube PCR test for the diagnosis of Angelman and Prader-Willi syndrome based on allelic methylation differences at the SNRPN locus.
European journal of human genetics : EJHG 1997;5(2):94-8.
1997: Zeschnigk M; Schmitz B; Dittrich B; Buiting K; Horsthemke B; Doerfler W
Imprinted segments in the human genome: different DNA methylation patterns in the Prader-Willi/Angelman syndrome region as determined by the genomic sequencing method.
Human molecular genetics 1997;6(3):387-95.
1997: Schubbert R; Renz D; Schmitz B; Doerfler W
Foreign (M13) DNA ingested by mice reaches peripheral leukocytes, spleen, and liver via the intestinal wall mucosa and can be covalently linked to mouse DNA.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(3):961-6.
1996: Schiedner G; Doerfler W
Insufficient levels of NFIII and its low affinity for the origin of adenovirus type 12 (Ad12) DNA replication contribute to the abortive infection of BHK21 hamster cells by Ad12.
Journal of virology 1996;70(11):8003-9.
1996: Doerfler W
A new concept in (adenoviral) oncogenesis: integration of foreign DNA and its consequences.
Biochimica et biophysica acta 1996;1288(2):F79-99.
1996: Koetsier P A; Doerfler W
A simple device to prevent contamination during spin-column gel filtration.
Trends in genetics : TIG 1996;12(9):339.
1996: Koetsier P A; Mangel L; Schmitz B; Doerfler W
Stability of transgene methylation patterns in mice: position effects, strain specificity and cellular mosaicism.
Transgenic research 1996;5(4):235-44.
1996: Kochanek S; Hosokawa K; Schiedner G; Renz D; Doerfler W
DNA methylation in the promoter of ribosomal RNA genes in human cells as determined by genomic sequencing.
FEBS letters 1996;388(2-3):192-4.
1996: Knoblauch M; Schröer J; Schmitz B; Doerfler W
The structure of adenovirus type 12 DNA integration sites in the hamster cell genome.
Journal of virology 1996;70(6):3788-96.
1996: Deissler H; Behn-Krappa A; Doerfler W
Purification of nuclear proteins from human HeLa cells that bind specifically to the unstable tandem repeat (CGG)n in the human FMR1 gene.
The Journal of biological chemistry 1996;271(8):4327-34.
1996: Koetsier P A; Doerfler W
Influence of mouse-strain-specific factors on position-dependent transgene DNA methylation patterns.
Acta geneticae medicae et gemellologiae 1996;45(1-2):243-4.
1996: Meyer zu Altenschildesche G; Heller H; Wilgenbus P; Tjia S T; Doerfler W
Chromosomal distribution of the hamster intracisternal A-particle (IAP) retrotransposons.
Chromosoma 1996;104(5):341-4.
1995: Deissler H; Genç B; Doerfler W
Restriction endonuclease BsoFI is sensitive to the 5'-methylation of deoxycytidines in its recognition sequence.
Nucleic acids research 1995;23(21):4227-8.
1995: Orend G; Knoblauch M; Doerfler W
Selective loss of unmethylated segments of integrated Ad12 genomes in revertants of the adenovirus type 12-transformed cell line T637.
Virus research 1995;38(2-3):261-7.
1995: Heller H; Kämmer C; Wilgenbus P; Doerfler W
Chromosomal insertion of foreign (adenovirus type 12, plasmid, or bacteriophage lambda) DNA is associated with enhanced methylation of cellular DNA segments.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(12):5515-9.
1995: Doerfler W; Orend G; Schubbert R; Fechteler K; Heller H; Wilgenbus P; Schröer J
On the insertion of foreign DNA into mammalian genomes: mechanism and consequences.
Gene 1995;157(1-2):241-5.
1995: Munnes M; Schetter C; Hölker I; Doerfler W
A fully 5'-CG-3' but not a 5'-CCGG-3' methylated late frog virus 3 promoter retains activity.
Journal of virology 1995;69(4):2240-7.
1995: Kämmer C; Doerfler W
Genomic sequencing reveals absence of DNA methylation in the major late promoter of adenovirus type 2 DNA in the virion and in productively infected cells.
FEBS letters 1995;362(3):301-5.
1995: Kochanek S; Renz D; Doerfler W
Transcriptional silencing of human Alu sequences and inhibition of protein binding in the box B regulatory elements by 5'-CG-3' methylation.
FEBS letters 1995;360(2):115-20.
1995: Orend G; Knoblauch M; Kämmer C; Tjia S T; Schmitz B; Linkwitz A; Meyer G; Maas J; Doerfler W
The initiation of de novo methylation of foreign DNA integrated into a mammalian genome is not exclusively targeted by nucleotide sequence.
Journal of virology 1995;69(2):1226-42.
1995: Doerfler W
The insertion of foreign DNA into mammalian genomes and its consequences: a concept in oncogenesis.
Advances in cancer research 1995;66():313-44.
1995: Sprengel J; Schmitz B; Heuss-Neitzel D; Doerfler W
The complete nucleotide sequence of the DNA of human adenovirus type 12.
Current topics in microbiology and immunology 1995;199 ( Pt 2)():189-274.
1995: Fechteler K; Tatzelt J; Huppertz S; Wilgenbus P; Doerfler W
The mechanism of adenovirus DNA integration: studies in a cell-free system.
Current topics in microbiology and immunology 1995;199 ( Pt 2)():109-37.
1995: Doerfler W
Uptake of foreign DNA by mammalian cells via the gastrointestinal tract in mice: methylation of foreign DNA--a cellular defense mechanism.
Current topics in microbiology and immunology 1995;197():209-24.
1994: Schiedner G; Schmitz B; Doerfler W
Late transcripts of adenovirus type 12 DNA are not translated in hamster cells expressing the E1 region of adenovirus type 5.
Journal of virology 1994;68(9):5476-82.
1994: Kochanek S; Renz D; Doerfler W
Variability in allelic DNA methylation in spermatozoa.
Human genetics 1994;94(2):203-6.
1994: Muiznieks I; Doerfler W
The topology of the promoter of RNA polymerase II- and III-transcribed genes is modified by the methylation of 5'-CG-3' dinucleotides.
Nucleic acids research 1994;22(13):2568-75.
1994: Muiznieks I; Doerfler W
The impact of 5'-CG-3' methylation on the activity of different eukaryotic promoters: a comparative study.
FEBS letters 1994;344(2-3):251-4.
1994: Schubbert R; Lettmann C; Doerfler W
Ingested foreign (phage M13) DNA survives transiently in the gastrointestinal tract and enters the bloodstream of mice.
Molecular & general genetics : MGG 1994;242(5):495-504.
1994: Sprengel J; Schmitz B; Heuss-Neitzel D; Zock C; Doerfler W
Nucleotide sequence of human adenovirus type 12 DNA: comparative functional analysis.
Journal of virology 1994;68(1):379-89.
1994: Orend G; Linkwitz A; Doerfler W
Selective sites of adenovirus (foreign) DNA integration into the hamster genome: changes in integration patterns.
Journal of virology 1994;68(1):187-94.
1994: Behn-Krappa A; Doerfler W
Enzymatic amplification of synthetic oligodeoxyribonucleotides: implications for triplet repeat expansions in the human genome.
Human mutation 1994;3(1):19-24.
1993: Kochanek S; Renz D; Doerfler W
Differences in the accessibility of methylated and unmethylated DNA to DNase I.
Nucleic acids research 1993;21(25):5843-5.
1993: Schetter C; Grünemann B; Hölker I; Doerfler W
Patterns of frog virus 3 DNA methylation and DNA methyltransferase activity in nuclei of infected cells.
Journal of virology 1993;67(12):6973-8.
1993: Behn-Krappa A; Mollenhauer J; Doerfler W
Triplet repeat sequences in human DNA can be detected by hybridization to a synthetic (5'-CGG-3')17 oligodeoxyribonucleotide.
FEBS letters 1993;333(3):248-50.
1993: Koetsier P A; Schorr J; Doerfler W
A rapid optimized protocol for downward alkaline Southern blotting of DNA.
BioTechniques 1993;15(2):260-2.
1993: Tatzelt J; Fechteler K; Langenbach P; Doerfler W
Fractionated nuclear extracts from hamster cells catalyze cell-free recombination at selective sequences between adenovirus DNA and a hamster preinsertion site.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(15):7356-60.
1993: Behn-Krappa A; Doerfler W
The state of DNA methylation in the promoter and exon 1 regions of the human gene for the interleukin-2 receptor alpha chain (IL-2R alpha) in various cell types.
Human molecular genetics 1993;2(7):993-9.
1993: Kochanek S; Renz D; Doerfler W
Probing DNA-protein interactions in vitro with the CpG DNA methyltransferase.
Nucleic acids research 1993;21(10):2339-42.
1993: Schorr J; Doerfler W
Non-homologous recombination between adenovirus and AcNPV DNA fragments in cell-free extracts from insect Spodoptera frugiperda nuclei.
Virus research 1993;28(2):153-70.
1993: Kochanek S; Renz D; Doerfler W
DNA methylation in the Alu sequences of diploid and haploid primary human cells.
The EMBO journal 1993;12(3):1141-51.
1993: Zock C; Iselt A; Doerfler W
A unique mitigator sequence determines the species specificity of the major late promoter in adenovirus type 12 DNA.
Journal of virology 1993;67(2):682-93.
1993: Doerfler W
Patterns of de novo DNA methylation and promoter inhibition: studies on the adenovirus and the human genomes.
EXS 1993;64():262-99.
1993: Doerfler W
Adenoviral DNA integration and changes in DNA methylation patterns: a different view of insertional mutagenesis.
Progress in nucleic acid research and molecular biology 1993;46():1-36.
1992: Tatzelt J; Scholz B; Fechteler K; Jessberger R; Doerfler W
Recombination between adenovirus type 12 DNA and a hamster preinsertion sequence in a cell-free system. Patch homologies and fractionation of nuclear extracts.
Journal of molecular biology 1992;228(4):1275.
1992: Rosahl T; Doerfler W
Alterations in the levels of expression of specific cellular genes in adenovirus-infected and -transformed cells.
Virus research 1992;26(1):71-90.
1992: Tatzelt J; Scholz B; Fechteler K; Jessberger R; Doerfler W
Recombination between adenovirus type 12 DNA and a hamster preinsertion sequence in a cell-free system. Patch homologies and fractionation of nuclear extracts.
Journal of molecular biology 1992;226(1):117-26.
1992: Krappa R; Behn-Krappa A; Jahnel F; Doerfler W; Knebel-Mörsdorf D
Differential factor binding at the promoter of early baculovirus gene PE38 during viral infection: GATA motif is recognized by an insect protein.
Journal of virology 1992;66(6):3494-503.
1991: Lettmann C; Schmitz B; Doerfler W
Persistence or loss of preimposed methylation patterns and de novo methylation of foreign DNA integrated in transgenic mice.
Nucleic acids research 1991;19(25):7131-7.
1991: Xiong G M; Schorr J; Tjia S T; Doerfler W
Heterologous recombination between Autographa californica nuclear polyhedrosis virus DNA and foreign DNA in non-polyhedrin segments of the viral genome.
Virus research 1991;21(1):65-85.
1991: Behn-Krappa A; Hölker I; Sandaradura de Silva U; Doerfler W
Patterns of DNA methylation are indistinguishable in different individuals over a wide range of human DNA sequences.
Genomics 1991;11(1):1-7.
1991: Orend G; Kuhlmann I; Doerfler W
Spreading of DNA methylation across integrated foreign (adenovirus type 12) genomes in mammalian cells.
Journal of virology 1991;65(8):4301-8.
1991: Achten S; Behn-Krappa A; Jücker M; Sprengel J; Hölker I; Schmitz B; Tesch H; Diehl V; Doerfler W
Patterns of DNA methylation in selected human genes in different Hodgkin's lymphoma and leukemia cell lines and in normal human lymphocytes.
Cancer research 1991;51(14):3702-9.
1991: Kochanek S; Radbruch A; Tesch H; Renz D; Doerfler W
DNA methylation profiles in the human genes for tumor necrosis factors alpha and beta in subpopulations of leukocytes and in leukemias.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(13):5759-63.
1991: Jüttermann R; Hosokawa K; Kochanek S; Doerfler W
Adenovirus type 2 VAI RNA transcription by polymerase III is blocked by sequence-specific methylation.
Journal of virology 1991;65(4):1735-42.
1991: Hermann R; Doerfler W
Interference with protein binding at AP2 sites by sequence-specific methylation in the late E2A promoter of adenovirus type 2 DNA.
FEBS letters 1991;281(1-2):191-5.
1991: Happ B; Li J; Doerfler W
Proteins encoded in the 81.2- to 85.0-map-unit fragment of Autographa californica nuclear polyhedrosis virus DNA can be translated in vitro and in Spodoptera frugiperda cells.
Journal of virology 1991;65(1):89-97.
1991: Doerfler W
Abortive infection and malignant transformation by adenoviruses: integration of viral DNA and control of viral gene expression by specific patterns of DNA methylation.
Advances in virus research 1991;39():89-128.
1990: Kochanek S; Toth M; Dehmel A; Renz D; Doerfler W
Interindividual concordance of methylation profiles in human genes for tumor necrosis factors alpha and beta.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(22):8830-4.
1990: Doerfler W; Toth M; Kochanek S; Achten S; Freisem-Rabien U; Behn-Krappa A; Orend G
Eukaryotic DNA methylation: facts and problems.
FEBS letters 1990;268(2):329-33.
1990: Toth M; Müller U; Doerfler W
Establishment of de novo DNA methylation patterns. Transcription factor binding and deoxycytidine methylation at CpG and non-CpG sequences in an integrated adenovirus promoter.
Journal of molecular biology 1990;214(3):673-83.
1990: Li J A; Happ B; Schetter C; Oellig C; Hauser C; Kuroda K; Knebel-Mörsdorf D; Klenk H D; Doerfler W
The expression of the Autographa californica nuclear polyhedrosis virus genome in insect cells.
Veterinary microbiology 1990;23(1-4):73-8.
1990: Zock C; Doerfler W
A mitigator sequence in the downstream region of the major late promoter of adenovirus type 12 DNA.
The EMBO journal 1990;9(5):1615-23.
1990: Schetter C; Oellig C; Doerfler W
An insertion of insect cell DNA in the 81-map-unit segment of Autographa californica nuclear polyhedrosis virus DNA.
Journal of virology 1990;64(4):1844-50.
1990: Doerfler W
The significance of DNA methylation patterns: promoter inhibition by sequence-specific methylation is one functional consequence.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 1990;326(1235):253-65.
1989: Hermann R; Hoeveler A; Doerfler W
Sequence-specific methylation in a downstream region of the late E2A promoter of adenovirus type 2 DNA prevents protein binding.
Journal of molecular biology 1989;210(2):411-5.
1989: Jüttermann R; Weyer U; Doerfler W
Defect of adenovirus type 12 replication in hamster cells: absence of transcription of viral virus-associated and L1 RNAs.
Journal of virology 1989;63(8):3535-40.
1989: Doerfler W; Hoeveler A; Weisshaar B; Dobrzanski P; Knebel D; Langner K D; Achten S; Müller U
Promoter inactivation or inhibition by sequence-specific methylation and mechanisms of reactivation.
Cell biophysics 1989;15(1-2):21-7.
1989: Knust B; Brüggemann U; Doerfler W
Reactivation of a methylation-silenced gene in adenovirus-transformed cells by 5-azacytidine or by E1A trans activation.
Journal of virology 1989;63(8):3519-24.
1989: Jessberger R; Weisshaar B; Stabel S; Doerfler W
Arrangement and expression of integrated adenovirus type 12 DNA in the transformed hamster cell line HA12/7: amplification of Ad12 and c-myc DNAs and evidence for hybrid viral-cellular transcripts.
Virus research 1989;13(2):113-28.
1989: Toth M; Lichtenberg U; Doerfler W
Genomic sequencing reveals a 5-methylcytosine-free domain in active promoters and the spreading of preimposed methylation patterns.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(10):3728-32.
1989: Jessberger R; Heuss D; Doerfler W
Recombination in hamster cell nuclear extracts between adenovirus type 12 DNA and two hamster preinsertion sequences.
The EMBO journal 1989;8(3):869-78.
1989: Bartnik E; Doerfler W
Chromatin structure and levels of expression and DNA methylation in the E3 region of chromosomally integrated adenovirus type 12 DNA.
Biochimica et biophysica acta 1989;1007(2):228-32.
1989: Doerfler W
Malignant transformation of cells by DNA viruses: adenovirus DNA integration in the mammalian genome.
Critical reviews in oncogenesis 1989;1(2):211-9.
1988: Doerfler W; Weisshaar B; Hoeveler A; Knebel D; Müller U; Dobrzanski P; Lichtenberg U; Achten S; Hermann R
Promoter inhibition by DNA methylation: a reversible signal.
Gene 1988;74(1):129-33.
1988: Lichtenberg U; Zock C; Doerfler W
Integration of foreign DNA into mammalian genome can be associated with hypomethylation at site of insertion.
Virus research 1988;11(4):335-42.
1988: Hauser C; Fusswinkel H; Li J; Oellig C; Kunze R; Müller-Neumann M; Heinlein M; Starlinger P; Doerfler W
Overproduction of the protein encoded by the maize transposable element Ac in insect cells by a baculovirus vector.
Molecular & general genetics : MGG 1988;214(3):373-8.
1988: Dobrzanski P; Hoeveler A; Doerfler W
Inactivation by sequence-specific methylations of adenovirus promoters in a cell-free transcription system.
Journal of virology 1988;62(11):3941-6.
1988: Knebel-Mörsdorf D; Achten S; Langner K D; Rüger R; Fleckenstein B; Doerfler W
Reactivation of the methylation-inhibited late E2A promoter of adenovirus type 2 by a strong enhancer of human cytomegalovirus.
Virology 1988;166(1):166-74.
1988: Weisshaar B; Langner K D; Jüttermann R; Müller U; Zock C; Klimkait T; Doerfler W
Reactivation of the methylation-inactivated late E2A promoter of adenovirus type 2 by E1A (13 S) functions.
Journal of molecular biology 1988;202(2):255-70.
1988: Geisel J; Weisshaar B; Oette K; Doerfler W
A new Apa LI restriction fragment length polymorphism in the low density lipoprotein receptor gene.
Journal of clinical chemistry and clinical biochemistry. Zeitschrift für klinische Chemie und klinische Biochemie 1988;26(7):429-33.
1988: Rosahl T; Doerfler W
Predominant association of adenovirus type 12 DNA with human chromosome 1 early in productive infection.
Virology 1988;162(2):494-7.
1987: Müller U; Doerfler W
Fixation of the unmethylated or the 5'-CCGG-3' methylated adenovirus late E2A promoter-cat gene construct in the genome of hamster cells: gene expression and stability of methylation patterns.
Journal of virology 1987;61(12):3710-20.
1987: Klimkait T; Doerfler W
E1B functions of type C adenoviruses play a role in the complementation of blocked adenovirus type 12 DNA replication and late gene transcription in hamster cells.
Virology 1987;161(1):109-20.
1987: Knebel D; Doerfler W
Activation of an insect baculovirus promoter in mammalian cells by adenovirus functions.
Virus research 1987;8(4):317-26.
1987: Oellig C; Happ B; Müller T; Doerfler W
Overlapping sets of viral RNAs reflect the array of polypeptides in the EcoRI J and N fragments (map positions 81.2 to 85.0) of the Autographa californica nuclear polyhedrosis virus genome.
Journal of virology 1987;61(10):3048-57.
1987: Hoeveler A; Doerfler W
Specific factors binding to the late E2A promoter region of adenovirus type 2 DNA: no apparent effects of 5'-CCGG-3' methylation.
DNA (Mary Ann Liebert, Inc.) 1987;6(5):449-60.
1987: Lichtenberg U; Zock C; Doerfler W
Insertion of adenovirus type 12 DNA in the vicinity of an intracisternal A particle genome in Syrian hamster tumor cells.
Journal of virology 1987;61(9):2719-26.
1987: Geisel J; Weisshaar B; Oette K; Mechtel M; Doerfler W
Double Msp I RFLP in the human LDL receptor gene.
Nucleic acids research 1987;15(9):3943.
1986: Langner K D; Weyer U; Doerfler W
Trans effect of the E1 region of adenoviruses on the expression of a prokaryotic gene in mammalian cells: resistance to 5' -CCGG- 3' methylation.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(6):1598-1602.
1985: Doerfler W; Langner K D; Knebel D; Weyer U; Dobrzanski P; Knust-Kron B
Site-specific promoter methylations and gene inactivation.
Progress in clinical and biological research 1985;198():133-55.
1982: Vardimon L; Günthert U; Doerfler W
In vitro methylation of the BsuRI (5'-GGCC-3') sites in the E2a region of adenovirus type 2 DNA does not affect expression in Xenopus laevis oocytes.
Molecular and cellular biology 1982;2(12):1574-80.

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