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Mariam Dohadwala

Research Profile

Chemicals & Drugs

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Miranda Dennis; Mariam Dohadwala; Steven M Dubinett; David A Elashoff; Yuan Lin; Jie Luo; Sherven Sharma; Elliot Abemayor; Guanyu Wang; Maie A St John
Snail controls the mesenchymal phenotype and drives erlotinib resistance in oral epithelial and head and neck squamous cell carcinoma cells.
M A St John; G Wang; S L Zaknoen; F J Burrows; M Dennis; Mariam Dohadwala; D Elashoff; D Hu; T Lawhon; J M Lee; Y Lin; J Luo; S M Dubinett
Apricoxib upregulates 15-PGDH and PGT in tobacco-related epithelial malignancies.
Mariam Dohadwala; Guanyu Wang; Eileen Heinrich; Jie Luo; Ontario Lau; Hubert Shih; Qahera Munaim; Gina Lee; Longsheng Hong; Chi Lai; Elliot Abemayor; Michael C Fishbein; David Elashoff; Steven M Dubinett; Maie A R St John
The role of ZEB1 in the inflammation-induced promotion of EMT in HNSCC.

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2012: Miranda Dennis; Mariam Dohadwala; Steven M Dubinett; David A Elashoff; Yuan Lin; Jie Luo; Sherven Sharma; Elliot Abemayor; Guanyu Wang; Maie A St John
Snail controls the mesenchymal phenotype and drives erlotinib resistance in oral epithelial and head and neck squamous cell carcinoma cells.
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 2012;147(4):726-32.
2012: M A St John; G Wang; S L Zaknoen; F J Burrows; M Dennis; Mariam Dohadwala; D Elashoff; D Hu; T Lawhon; J M Lee; Y Lin; J Luo; S M Dubinett
Apricoxib upregulates 15-PGDH and PGT in tobacco-related epithelial malignancies.
British journal of cancer 2012;107(4):707-12.
2010: Mariam Dohadwala; Guanyu Wang; Eileen Heinrich; Jie Luo; Ontario Lau; Hubert Shih; Qahera Munaim; Gina Lee; Longsheng Hong; Chi Lai; Elliot Abemayor; Michael C Fishbein; David Elashoff; Steven M Dubinett; Maie A R St John
The role of ZEB1 in the inflammation-induced promotion of EMT in HNSCC.
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 2010;142(5):753-9.
2009: Jane Yanagawa; Tonya C Walser; Li X Zhu; Longsheng Hong; Michael C Fishbein; Vei Mah; David Chia; Lee Goodglick; David Elashoff; Jie Luo; Clara E Magyar; Mariam Dohadwala; Jay M Lee; Maie A St John; Robert M Strieter; Sherven Sharma; Steven M Dubinett
Snail promotes CXCR2 ligand-dependent tumor progression in non-small cell lung carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(22):6820-9.
2009: Maie A R St John; Mariam Dohadwala; Jie Luo; Guanyu Wang; Gina Lee; Hubert Shih; Eileen Heinrich; Kostyantyn Krysan; Tonya Walser; Saswati Hazra; Li Zhu; Chi Lai; Elliot Abemayor; Michael Fishbein; David Elashoff; Sherven Sharma; Steven M Dubinett
Proinflammatory mediators upregulate snail in head and neck squamous cell carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(19):6018-27.
2008: Karen Reckamp; Brian Gardner; Robert A Figlin; David Elashoff; Kostyantyn Krysan; Mariam Dohadwala; Jenny Mao; Sherven Sharma; Landon Inge; Ayyappan Rajasekaran; Steven M Dubinett
Tumor response to combination celecoxib and erlotinib therapy in non-small cell lung cancer is associated with a low baseline matrix metalloproteinase-9 and a decline in serum-soluble E-cadherin.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2008;3(2):117-24.
2008: Kostyantyn Krysan; Jay M Lee; Mariam Dohadwala; Brian Gardner; Karen Reckamp; Edward Garon; Maie St John; Sherven Sharma; Steven M Dubinett
Inflammation, epithelial to mesenchymal transition, and epidermal growth factor receptor tyrosine kinase inhibitor resistance.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2008;3(2):107-10.
2007: Katherine A Peebles; Jay M Lee; Jenny T Mao; Saswati Hazra; Karen Reckamp; Kostyantyn Krysan; Mariam Dohadwala; Eileen L Heinrich; Tonya C Walser; Xiaoyan Cui; Felicita Baratelli; Edward Garon; Sherven Sharma; Steven M Dubinett
Inflammation and lung carcinogenesis: applying findings in prevention and treatment.
Expert review of anticancer therapy 2007;7(10):1405-21.
2006: Mariam Dohadwala; Seok-Chul Yang; Jie Luo; Sherven Sharma; Raj K Batra; Min Huang; Ying Lin; Lee Goodglick; Kostyantyn Krysan; Michael C Fishbein; Longsheng Hong; Chi Lai; Robert B Cameron; Robert M Gemmill; Harry A Drabkin; Steven M Dubinett
Cyclooxygenase-2-dependent regulation of E-cadherin: prostaglandin E(2) induces transcriptional repressors ZEB1 and snail in non-small cell lung cancer.
Cancer research 2006;66(10):5338-45.
2005: Harnisha Dalwadi; Kostyantyn Krysan; Nathalie Heuze-Vourc'h; Mariam Dohadwala; David Elashoff; Sherven Sharma; Nicholas Cacalano; Alan Lichtenstein; Steven M Dubinett
Cyclooxygenase-2-dependent activation of signal transducer and activator of transcription 3 by interleukin-6 in non-small cell lung cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(21):7674-82.
2005: Felicita Baratelli; Ying Lin; Li Zhu; Seok-Chul Yang; Nathalie Heuzé-Vourc'h; Gang Zeng; Karen Reckamp; Mariam Dohadwala; Sherven Sharma; Steven M Dubinett
Prostaglandin E2 induces FOXP3 gene expression and T regulatory cell function in human CD4+ T cells.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(3):1483-90.
2005: Felicita Baratelli; Kostyantyn Krysan; Nathalie Heuzé-Vourc'h; Li Zhu; Brian Escuadro; Sherven Sharma; Karen Reckamp; Mariam Dohadwala; Steven M Dubinett
PGE2 confers survivin-dependent apoptosis resistance in human monocyte-derived dendritic cells.
Journal of leukocyte biology 2005;78(2):555-64.
2005: Kostyantyn Krysan; Karen Reckamp; Harnisha Dalwadi; Sherven Sharma; Enrique Rozengurt; Mariam Dohadwala; Steven M Dubinett
Prostaglandin E2 activates mitogen-activated protein kinase/Erk pathway signaling and cell proliferation in non-small cell lung cancer cells in an epidermal growth factor receptor-independent manner.
Cancer research 2005;65(14):6275-81.
2004: Felicita Baratelli; Nathalie Heuzé-Vourc'h; Kostyantyn Krysan; Mariam Dohadwala; Karen Riedl; Sherven Sharma; Steven M Dubinett
Prostaglandin E2-dependent enhancement of tissue inhibitors of metalloproteinases-1 production limits dendritic cell migration through extracellular matrix.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(9):5458-66.
2004: Mehis Põld; Kostyantyn Krysan; Anu Põld; Mariam Dohadwala; Nathalie Heuze-Vourc'h; Jenny T Mao; Karen L Riedl; Sherven Sharma; Steven M Dubinett
Cyclooxygenase-2 modulates the insulin-like growth factor axis in non-small-cell lung cancer.
Cancer research 2004;64(18):6549-55.
2004: Min Qin; Brian Escuadro; Mariam Dohadwala; Sherven Sharma; Raj K Batra
A novel role for the coxsackie adenovirus receptor in mediating tumor formation by lung cancer cells.
Cancer research 2004;64(18):6377-80.
2004: Karen Riedl; Kostyantyn Krysan; Mehis Põld; Harnisha Dalwadi; Nathalie Heuze-Vourc'h; Mariam Dohadwala; Ming Liu; Xiaoyan Cui; Robert Figlin; Jenny T Mao; Robert M Strieter; Sherven Sharma; Steven M Dubinett
Multifaceted roles of cyclooxygenase-2 in lung cancer.
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2004;7(3):169-84.
2004: Kostyantyn Krysan; Mariam Dohadwala; Jie Luo; Ying Lin; Li Zhu; Nathalie Heuze-Vourc'h; Lee Goodglick; Farrukh Merchant; David Seligson; Mehis Pold; Robert M Strieter; Sherven Sharma; Steven M Dubinett
Cyclooxygenase-2-dependent expression of survivin in non-small cell lung cancer.
Chest 2004;125(5 Suppl):140S.
2004: Mehis Põld; Li X Zhu; Sherven Sharma; Marie D Burdick; Ying Lin; Peter P N Lee; Anu Põld; Jie Luo; Kostyantyn Krysan; Mariam Dohadwala; Jenny T Mao; Raj K Batra; Robert M Strieter; Steven M Dubinett
Cyclooxygenase-2-dependent expression of angiogenic CXC chemokines ENA-78/CXC Ligand (CXCL) 5 and interleukin-8/CXCL8 in human non-small cell lung cancer.
Cancer research 2004;64(5):1853-60.
2004: Kostyantyn Krysan; Farrukh H Merchant; Li Zhu; Mariam Dohadwala; Jie Luo; Ying Lin; Nathalie Heuze-Vourc'h; Mehis Põld; David Seligson; David Chia; Lee Goodglick; Hejing Wang; Robert M Strieter; Sherven Sharma; Steven M Dubinett
COX-2-dependent stabilization of survivin in non-small cell lung cancer.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2004;18(1):206-8.
2003: Sherven Sharma; Marina Stolina; Seok-Chul Yang; Felicita Baratelli; Jeff F Lin; Kimberly Atianzar; Jie Luo; Li Zhu; Ying Lin; Min Huang; Mariam Dohadwala; Raj K Batra; Steven M Dubinett
Tumor cyclooxygenase 2-dependent suppression of dendritic cell function.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(3):961-8.
2003: Raj K Batra; Ying Lin; Sherven Sharma; Mariam Dohadwala; Jie Luo; Mehis Pold; Steven M Dubinett
Non-small cell lung cancer-derived soluble mediators enhance apoptosis in activated T lymphocytes through an I kappa B kinase-dependent mechanism.
Cancer research 2003;63(3):642-6.
2003: Steven M Dubinett; Sherven Sharma; Min Huang; Mariam Dohadwala; Mehis Pold; Jenny T Mao
Cyclooxygenase-2 in lung cancer.
Progress in experimental tumor research 2003;37():138-62.
2003: Sherven Sharma; Min Huang; Mariam Dohadwala; Mehis Pold; Raj K Batra; Steven M Dubinett
Cyclooxygenase 2-dependent regulation of antitumor immunity in lung cancer.
Methods in molecular medicine 2003;75():723-36.
2002: Mariam Dohadwala; Raj K Batra; Jie Luo; Ying Lin; Kostyantyn Krysan; Mehis Pold; Sherven Sharma; Steven M Dubinett
Autocrine/paracrine prostaglandin E2 production by non-small cell lung cancer cells regulates matrix metalloproteinase-2 and CD44 in cyclooxygenase-2-dependent invasion.
The Journal of biological chemistry 2002;277(52):50828-33.
2002: Min Huang; Sherven Sharma; Li X Zhu; Michael P Keane; Jie Luo; Ling Zhang; Marie D Burdick; Ying Q Lin; Mariam Dohadwala; Brian Gardner; Raj K Batra; Robert M Strieter; Steven M Dubinett
IL-7 inhibits fibroblast TGF-beta production and signaling in pulmonary fibrosis.
The Journal of clinical investigation 2002;109(7):931-7.
2002: Mehis Põld; Mariam Dohadwala; Jie Luo; Ying Lin; Steven M Dubinett
Microarray identifies cyclo-oxygenase-2-dependent modulation of insulin-like growth factor binding protein-3 in non-small cell lung cancer cells.
Chest 2002;121(3 Suppl):29S-30S.
2001: Mariam Dohadwala; Jie Luo; Li Zhu; Ying Lin; Graeme Dougherty; Sherven Sharma; Min Huang; Mehis Pold; Raj K Batra; Steven M Dubinett
Non-small cell lung cancer cyclooxygenase-2-dependent invasion is mediated by CD44.
The Journal of biological chemistry 2001;276(24):20809-12.
2000: PW Miller; Sherven Sharma; Marina Stolina; Lisa H Butterfield; J Luo; Y Lin; Mariam Dohadwala; Raj K Batra; L Wu; James S Economou; Steven M Dubinett
Intratumoral administration of adenoviral interleukin 7 gene-modified dendritic cells augments specific antitumor immunity and achieves tumor eradication.
Human gene therapy 2000;11(1):53-65.
2000: Marina Stolina; Sherven Sharma; Y Lin; Mariam Dohadwala; Brian Gardner; J Luo; Li Zhu; M Kronenberg; PW Miller; J Portanova; J C Lee; Steven M Dubinett
Specific inhibition of cyclooxygenase 2 restores antitumor reactivity by altering the balance of IL-10 and IL-12 synthesis.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(1):361-70.