M Dohlsten

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Forsberg G; Ohlsson L; Brodin T; Björk P; Lando P A; Shaw D; Stern P L; Dohlsten M
Therapy of human non-small-cell lung carcinoma using antibody targeting of a modified superantigen.
Boehncke W H; Hardt-Weinelt K; Nilsson H; Wolter M; Dohlsten M; Ochsendorf F R; Kaufmann R; Antonsson P
Antagonistic effects of the staphylococcal enterotoxin a mutant, SEA(F47A/D227A), on psoriasis in the SCID-hu xenogeneic transplantation model.
Parra E; Mustelin T; Dohlsten M; Mercola D
Identification of a CD28 response element in the CD40 ligand promoter.

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All Publications

2001: Forsberg G; Ohlsson L; Brodin T; Björk P; Lando P A; Shaw D; Stern P L; Dohlsten M
Therapy of human non-small-cell lung carcinoma using antibody targeting of a modified superantigen.
British journal of cancer 2001;85(1):129-36.
2001: Boehncke W H; Hardt-Weinelt K; Nilsson H; Wolter M; Dohlsten M; Ochsendorf F R; Kaufmann R; Antonsson P
Antagonistic effects of the staphylococcal enterotoxin a mutant, SEA(F47A/D227A), on psoriasis in the SCID-hu xenogeneic transplantation model.
The Journal of investigative dermatology 2001;116(4):596-601.
2001: Parra E; Mustelin T; Dohlsten M; Mercola D
Identification of a CD28 response element in the CD40 ligand promoter.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(4):2437-43.
2000: Björkdahl O; Dohlsten M; Sjögren H O
Vaccination with B16 melanoma cells expressing a secreted form of interleukin-1beta induces tumor growth inhibition and an enhanced immunity against the wild-type B16 tumor.
Cancer gene therapy 2000;7(10):1365-74.
2000: Labuda T; Sundstedt A; Dohlsten M
Selective induction of p38 mitogen-activated protein kinase activity following A6H co-stimulation in primary human CD4(+) T cells.
International immunology 2000;12(3):253-61.
2000: Grundström S; Dohlsten M; Sundstedt A
IL-2 unresponsiveness in anergic CD4+ T cells is due to defective signaling through the common gamma-chain of the IL-2 receptor.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(3):1175-84.
2000: Rosendahl A; Kristensson K; Riesbeck K; Dohlsten M
T-cell cytotoxicity assays for studying the functional interaction between the superantigen staphylococcal enterotoxin A and T-cell receptors.
Methods in molecular biology (Clifton, N.J.) 2000;145():241-57.
1999: Nilsson H; Björk P; Dohlsten M; Antonsson P
Staphylococcal enterotoxin H displays unique MHC class II-binding properties.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(12):6686-93.
1999: Søgaard M; Ohlsson L; Kristensson K; Rosendahl A; Sjoberg A; Forsberg G; Kalland T; Dohlsten M
Treatment with tumor-reactive Fab-IL-2 and Fab-staphylococcal enterotoxin A fusion proteins leads to sustained T cell activation, and long-term survival of mice with established tumors.
International journal of oncology 1999;15(5):873-82.
1999: Litton M J; Dohlsten M; Rosendahl A; Ohlsson L; Søgaard M; Andersson J; Andersson U
The distinct role of CD4+ and CD8+ T-cells during the anti-tumour effects of targeted superantigens.
British journal of cancer 1999;81(2):359-66.
1999: Olsson C; Riesbeck K; Dohlsten M; Michaëlsson E;
CTLA-4 ligation suppresses CD28-induced NF-kappaB and AP-1 activity in mouse T cell blasts.
The Journal of biological chemistry 1999;274(20):14400-5.
1999: Labuda T; Gerwien J; Odum N; Dohlsten M
Rapid tyrosine phosphorylation of Lck following ligation of the tumor-associated cell surface molecule A6H.
International immunology 1999;11(3):427-33.
1999: Rosendahl A; Kristensson K; Carlsson M; Skartved N J; Riesbeck K; Søgaard M; Dohlsten M
Long-term survival and complete cures of B16 melanoma-carrying animals after therapy with tumor-targeted IL-2 and SEA.
International journal of cancer. Journal international du cancer 1999;81(1):156-63.
1999: Björkdahl O; Akerblad P; Gjörloff-Wingren A; Leanderson T; Dohlsten M
Lymphoid hyperplasia in transgenic mice over-expressing a secreted form of the human interleukin-1beta gene product.
Immunology 1999;96(1):128-37.
1999: Grosse-Hovest L; Brandl M; Dohlsten M; Kalland T; Wilmanns W; Jung G
Tumor-growth inhibition with bispecific antibody fragments in a syngeneic mouse melanoma model: the role of targeted T-cell co-stimulation via CD28.
International journal of cancer. Journal international du cancer 1999;80(1):138-44.
1999: Thulesen S; Jørgensen A; Gerwien J; Dohlsten M; Holst Nissen M; Odum N; Röpke C
Superantigens are presented by and activate thymocytes from infants.
Experimental and clinical immunogenetics 1999;16(4):226-33.
1998: Nielsen M B; Odum N; Gerwien J; Svejgaard A; Bendtzen K; Bregentholt S; Röpke C; Geisler C; Dohlsten M; Kaltoft K
Staphylococcal enterotoxin-A directly stimulates signal transduction and interferon-gamma production in psoriatic T-cell lines.
Tissue antigens 1998;52(6):530-8.
1998: Sundstedt A; Dohlsten M
In vivo anergized CD4+ T cells have defective expression and function of the activating protein-1 transcription factor.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(11):5930-6.
1998: Sundstedt A; Grundström S; Dohlsten M
T cell- and perforin-dependent depletion of B cells in vivo by staphylococcal enterotoxin A.
Immunology 1998;95(1):76-82.
1998: Riesbeck K; Billström A; Tordsson J; Brodin T; Kristensson K; Dohlsten M
Endothelial cells expressing an inflammatory phenotype are lysed by superantigen-targeted cytotoxic T cells.
Clinical and diagnostic laboratory immunology 1998;5(5):675-82.
1998: Labuda T; Wendt J; Hedlund G; Dohlsten M
ICAM-1 costimulation induces IL-2 but inhibits IL-10 production in superantigen-activated human CD4+ T cells.
Immunology 1998;94(4):496-502.
1998: Srinivas U; Dohlsten M; Kalland T; Lundblad A
Staphylococcal enterotoxin-A-induced in-vitro adhesion of HL-60 cells to endothelial cells involves both selectin and integrin families of cell adhesion molecules.
Scandinavian journal of immunology 1998;48(2):127-35.
1998: Parra E; McGuire K; Hedlund G; Dohlsten M
Overexpression of p65 and c-Jun substitutes for B7-1 costimulation by targeting the CD28RE within the IL-2 promoter.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(11):5374-81.
1998: Rosendahl A; Kristensson K; Hansson J; Riesbeck K; Kalland T; Dohlsten M
Perforin and IFN-gamma are involved in the antitumor effects of antibody-targeted superantigens.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(11):5309-13.
1998: Olsson C; Michaëlsson E; Parra E; Pettersson U; Lando P A; Dohlsten M
Biased dependency of CD80 versus CD86 in the induction of transcription factors regulating the human IL-2 promoter.
International immunology 1998;10(4):499-506.
1998: Gidlöf C; Carlson B; Dohlsten M; Tötterman T H
Antibody-directed superantigen-mediated T-cell killing of myeloid leukaemic cell line cells.
European journal of haematology 1998;60(4):233-9.
1998: Rosendahl A; Kristensson K; Hansson J; Ohlsson L; Kalland T; Dohlsten M
Repeated treatment with antibody-targeted superantigens strongly inhibits tumor growth.
International journal of cancer. Journal international du cancer 1998;76(2):274-83.
1998: Newton D W; Dohlsten M; Lando P A; Kalland T; Olsson C; Kotb M
MHC class II-independent, Vbeta-specific activation of T cells by superantigen mutants fused to anti-tumor Fab fragments: implications for use in treatment of human colon carcinoma.
International journal of molecular medicine 1998;1(1):157-62.
1998: Al-Daccak R; Mehindate K; Damdoumi F; Etongué-Mayer P; Nilsson H; Antonsson P; Sundström M; Dohlsten M; Sékaly R P; Mourad W
Staphylococcal enterotoxin D is a promiscuous superantigen offering multiple modes of interactions with the MHC class II receptors.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(1):225-32.
1998: Tötterman T H; Gidlöf C; Ragnarsson L; Högbom E; Lindeberg M; von der Lehr N; Einarsson A; Soegaard M; Kristensson K; Kalland T; Dohlsten M
Targeted superantigens for immunotherapy of haematopoietic tumours.
Vox sanguinis 1998;74 Suppl 2():483-7.
1997: Rosendahl A; Hansson J; Antonsson P; Sékaly R P; Kalland T; Dohlsten M
A mutation of F47 to A in staphylococcus enterotoxin A activates the T-cell receptor Vbeta repertoire in vivo.
Infection and immunity 1997;65(12):5118-24.
1997: Björkdahl O; Wingren A G; Hedhund G; Ohlsson L; Dohlsten M
Gene transfer of a hybrid interleukin-1 beta gene to B16 mouse melanoma recruits leucocyte subsets and reduces tumour growth in vivo.
Cancer immunology, immunotherapy : CII 1997;44(5):273-81.
1997: Krull F; Holzer U; Ihle J; Bethge W; Fierlbeck G; Kalland T; Dohlsten M; Niethammer D; Dannecker G E
Superantigen-induced lysis of melanoma cells.
Melanoma research 1997;7(3):214-22.
1997: Giantonio B J; Alpaugh R K; Schultz J; McAleer C; Newton D W; Shannon B; Guedez Y; Kotb M; Vitek L; Persson R; Gunnarsson P O; Kalland T; Dohlsten M; Persson B; Weiner L M
Superantigen-based immunotherapy: a phase I trial of PNU-214565, a monoclonal antibody-staphylococcal enterotoxin A recombinant fusion protein, in advanced pancreatic and colorectal cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1997;15(5):1994-2007.
1997: Litton M J; Dohlsten M; Hansson J; Rosendahl A; Ohlsson L; Kalland T; Andersson J; Andersson U
Tumor therapy with an antibody-targeted superantigen generates a dichotomy between local and systemic immune responses.
The American journal of pathology 1997;150(5):1607-18.
1997: Antonsson P; Wingren A G; Hansson J; Kalland T; Varga M; Dohlsten M
Functional characterization of the interaction between the superantigen staphylococcal enterotoxin A and the TCR.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(9):4245-51.
1997: Belfrage H; Dohlsten M; Hedlund G; Kalland T
Prevention of superantigen-induced tolerance in vivo by interleukin-2 treatment.
Cancer immunology, immunotherapy : CII 1997;44(2):77-82.
1997: Petersson E; Qi Z; Ekberg H; Ostraat O; Dohlsten M; Hedlund G
Activation of alloreactive natural killer cells is resistant to cyclosporine.
Transplantation 1997;63(8):1138-44.
1997: Thibodeau J; Dohlsten M; Cloutier I; Lavoie P M; Bjork P; Michel F; Léveillé C; Mourad W; Kalland T; Sékaly R P
Molecular characterization and role in T cell activation of staphylococcal enterotoxin A binding to the HLA-DR alpha-chain.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(8):3698-704.
1997: Hansson J; Ohlsson L; Persson R; Andersson G; Ilbäck N G; Litton M J; Kalland T; Dohlsten M
Genetically engineered superantigens as tolerable antitumor agents.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(6):2489-94.
1997: Gidlöf C; Dohlsten M; Lando P; Kalland T; Sundström C; Tötterman T H
A superantigen-antibody fusion protein for T-cell immunotherapy of human B-lineage malignancies.
Blood 1997;89(6):2089-97.
1997: Parra E; Varga M; Hedlund G; Kalland T; Dohlsten M
Costimulation by B7-1 and LFA-3 targets distinct nuclear factors that bind to the interleukin-2 promoter: B7-1 negatively regulates LFA-3-induced NF-AT DNA binding.
Molecular and cellular biology 1997;17(3):1314-23.
1997: Labuda T; Parra E; Hedlund G; Kalland T; Dohlsten M
The tumour associated cell surface antigen A6H is costimulatory for human CD4+ but not CD8+ T cells.
Immunology 1997;90(2):236-43.
1997: Belfrage H; Dohlsten M; Hedlund G; Kalland T
Prevention of superantigen-induced down-regulation of T-cell mediated cytotoxic activity by IL-2 in vivo.
Immunology 1997;90(2):183-8.
1997: Holzer U; Orlikowsky T; Zehrer C; Bethge W; Dohlsten M; Kalland T; Niethammer D; Dannecker G E
T-cell stimulation and cytokine release induced by staphylococcal enterotoxin A (SEA) and the SEAD227A mutant.
Immunology 1997;90(1):74-80.
1997: Petersson E; Ostraat O; Ekberg H; Hansson J; Simanaitis M; Brodin T; Dohlsten M; Hedlund G
Allogeneic heart transplantation activates alloreactive NK cells.
Cellular immunology 1997;175(1):25-32.
1997: Parra E; Wingren A G; Hedlund G; Kalland T; Dohlsten M
The role of B7-1 and LFA-3 in costimulation of CD8+ T cells.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(2):637-42.
1997: Sundstedt A; Höiden I; Rosendahl A; Kalland T; van Rooijen N; Dohlsten M
Immunoregulatory role of IL-10 during superantigen-induced hyporesponsiveness in vivo.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(1):180-6.
1996: Sundström M; Abrahmsén L; Antonsson P; Mehindate K; Mourad W; Dohlsten M
The crystal structure of staphylococcal enterotoxin type D reveals Zn2+-mediated homodimerization.
The EMBO journal 1996;15(24):6832-40.
1996: Zehrer C; Beck J; Gekeler V; Ihle J; Holzer U; Dohlsten M; Kalland T; Niethammer D; Dannecker G E
Superantigen-mediated cellular cytotoxicity is dependent on antigen expression, but independent of the P-glycoprotein multidrug resistance phenotype.
British journal of haematology 1996;95(3):452-6.
1996: Sundström M; Hallén D; Svensson A; Schad E; Dohlsten M; Abrahmsén L
The Co-crystal structure of staphylococcal enterotoxin type A with Zn2+ at 2.7 A resolution. Implications for major histocompatibility complex class II binding.
The Journal of biological chemistry 1996;271(50):32212-6.
1996: Yrlid U; Petersson E; Dohlsten M; Hedlund G
TCR alpha beta+ anti-tumor cytolytic T lymphocytes express NKR-P1 whilethe anti-tumor activity of TCR gamma delta+ T lymphocytes is not correlated to NKR-P1 expression.
Cellular immunology 1996;173(2):287-94.
1996: Newton D W; Dohlsten M; Olsson C; Segrén S; Lundin K E; Lando P A; Kalland T; Kotb M
Mutations in the MHC class II binding domains of staphylococcal enterotoxin A differentially affect T cell receptor Vbeta specificity.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(9):3988-94.
1996: Lando P A; Olsson C; Kalland T; Newton D; Kotb M; Dohlsten M
Regulation of superantigen-induced T cell activation in the absence and the presence of MHC class II.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(7):2857-63.
1996: Søgaard M; Hansson J; Litton M J; Ohlsson L; Rosendahl A; Lando P A; Antonsson P; Kalland T; Dohlsten M
Antibody-targeted superantigens in cancer immunotherapy.
Immunotechnology : an international journal of immunological engineering 1996;2(3):151-62.
1996: Rosendahl A; Hansson J; Sundstedt A; Kalland T; Dohlsten M
Immune response during tumor therapy with antibody-superantigen fusion proteins.
International journal of cancer. Journal international du cancer 1996;68(1):109-13.
1996: Wingren A G; Björkdahl O; Labuda T; Björk L; Andersson U; Gullberg U; Hedlund G; Sjögren H O; Kalland T; Widegren B; Dohlsten M
Fusion of a signal sequence to the interleukin-1 beta gene directs the protein from cytoplasmic accumulation to extracellular release.
Cellular immunology 1996;169(2):226-37.
1996: Sundstedt A; Sigvardsson M; Leanderson T; Hedlund G; Kalland T; Dohlsten M
In vivo anergized CD4+ T cells express perturbed AP-1 and NF-kappa B transcription factors.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(3):979-84.
1996: Litton M J; Dohlsten M; Lando P A; Kalland T; Ohlsson L; Andersson J; Andersson U
Antibody-targeted superantigen therapy induces tumor-infiltrating lymphocytes, excessive cytokine production, and apoptosis in human colon carcinoma.
European journal of immunology 1996;26(1):1-9.
1996: Antonsson P; Hansson J; Kalland T; Lando P A; Ohlsson L; Schad E; Svensson A; Dohlsten M
Genetically engineered superantigens in experimental tumor therapy.
Springer seminars in immunopathology 1996;17(4):397-410.
1995: Mehindate K; Thibodeau J; Dohlsten M; Kalland T; Sékaly R P; Mourad W
Cross-linking of major histocompatibility complex class II molecules by staphylococcal enterotoxin A superantigen is a requirement for inflammatory cytokine gene expression.
The Journal of experimental medicine 1995;182(5):1573-7.
1995: Dohlsten M; Hansson J; Ohlsson L; Litton M; Kalland T
Antibody-targeted superantigens are potent inducers of tumor-infiltrating T lymphocytes in vivo.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(21):9791-5.
1995: Dohlsten M; Lando P A; Björk P; Abrahmsén L; Ohlsson L; Lind P; Kalland T
Immunotherapy of human colon cancer by antibody-targeted superantigens.
Cancer immunology, immunotherapy : CII 1995;41(3):162-8.
1995: Gidlöf C; Dohlsten M; Kalland T; Tötterman T H
Antibodies are capable of directing superantigen-mediated T cell killing of chronic B lymphocytic leukemia cells.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1995;9(9):1534-42.
1995: Labuda T; Lando P; Björkdahl O; Kalland T; Vessella R; Hedlund G; Eriksson H; Sjögren H O; Dohlsten M
A novel co-stimulatory T cell antigen co-expressed on renal cell carcinoma.
International immunology 1995;7(9):1425-32.
1995: Belfrage H; Dohlsten M; Hedlund G; Kalland T
Enhanced and prolonged efficacy of superantigen-induced cytotoxic T lymphocyte activity by interleukin-2 in vivo.
Cancer immunology, immunotherapy : CII 1995;41(2):87-94.
1995: Holzer U; Bethge W; Krull F; Ihle J; Handgretinger R; Reisfeld R A; Dohlsten M; Kalland T; Niethammer D; Dannecker G E
Superantigen-staphylococcal-enterotoxin-A-dependent and antibody-targeted lysis of GD2-positive neuroblastoma cells.
Cancer immunology, immunotherapy : CII 1995;41(2):129-36.
1995: Lando P A; Dohlsten M; Ohlsson L; Kalland T
Tumor-reactive superantigens suppress tumor growth in humanized SCID mice.
International journal of cancer. Journal international du cancer 1995;62(4):466-71.
1995: Parra E; Varga M; Sigvardsson M; Hedlund G; Kalland T; Leanderson T; Sjögren H O; Dohlsten M
Costimulation of human CD4+ T cells with LFA-3 and B7 induce distinct effects on AP-1 and NF-kappa B transcription factors.
Journal of immunology (Baltimore, Md. : 1950) 1995;155(3):1132-40.
1995: Hedlund G; Hansson J; Ericsson P O; Sjögren H O; Dohlsten M
Expression of CD11a and CD45R isoforms defines distinct subsets of CD8+ TCR alpha beta and TCR gamma delta CTL in vivo.
Immunological reviews 1995;146():82-94.
1995: Schad E M; Zaitseva I; Zaitsev V N; Dohlsten M; Kalland T; Schlievert P M; Ohlendorf D H; Svensson L A
Crystal structure of the superantigen staphylococcal enterotoxin type A.
The EMBO journal 1995;14(14):3292-301.
1995: Abrahmsén L; Dohlsten M; Segrén S; Björk P; Jonsson E; Kalland T
Characterization of two distinct MHC class II binding sites in the superantigen staphylococcal enterotoxin A.
The EMBO journal 1995;14(13):2978-86.
1995: Sundstedt A; Höidén I; Hansson J; Hedlund G; Kalland T; Dohlsten M
Superantigen-induced anergy in cytotoxic CD8+ T cells.
Journal of immunology (Baltimore, Md. : 1950) 1995;154(12):6306-13.
1995: Ihle J; Holzer U; Krull F; Dohlsten M; Kalland T; Niethammer D; Dannecker G E
Antibody-targeted superantigens induce lysis of major histocompatibility complex class II-negative T-cell leukemia lines.
Cancer research 1995;55(3):623-8.
1995: Hansson J; Dohlsten M; Sjögren H O; Hedlund G
Distinct splicing of CD45 mRNA in activated rat gamma delta cytotoxic T lymphocytes.
European journal of immunology 1995;25(1):75-9.
1995: Wingren A G; Parra E; Varga M; Kalland T; Sjögren H O; Hedlund G; Dohlsten M
T cell activation pathways: B7, LFA-3, and ICAM-1 shape unique T cell profiles.
Critical reviews in immunology 1995;15(3-4):235-53.
1994: Dohlsten M; Abrahmsén L; Björk P; Lando P A; Hedlund G; Forsberg G; Brodin T; Gascoigne N R; Förberg C; Lind P
Monoclonal antibody-superantigen fusion proteins: tumor-specific agents for T-cell-based tumor therapy.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(19):8945-9.
1994: Hansson J; Ericsson P O; Widegren B; Dohlsten M; Sjögren H O; Hedlund G
Different types of in vivo induced cytolytic T lymphocytes are all LFA-Ihigh and lack CD45 exon 4 (CD45RA) but show distinct CD45RC profiles.
International immunology 1994;6(9):1375-81.
1994: Parra E; Wingren A G; Hedlund G; Björklund M; Sjögren H O; Kalland T; Sansom D; Dohlsten M
Costimulation of human CD4+ T lymphocytes with B7 and lymphocyte function-associated antigen-3 results in distinct cell activation profiles.
Journal of immunology (Baltimore, Md. : 1950) 1994;153(6):2479-87.
1994: Petersson E; Ostraat O; Hansson J; Ekberg H; Brodin T; Dohlsten M; Hedlund G
Alloselective natural killer cells are activated by allogeneic heart transplantation and can potentially play a functional role as classic CTLs.
Transplantation proceedings 1994;26(3):1732-3.
1994: Sundstedt A; Dohlsten M; Hedlund G; Höidén I; Björklund M; Kalland T
Superantigens anergize cytokine production but not cytotoxicity in vivo.
Immunology 1994;82(1):117-25.
1994: Belfrage H; Bhiladvala P; Hedlund G; Dohlsten M; Kalland T
Combined activation of murine lymphocytes with staphylococcal enterotoxin and interleukin-2 results in additive cytotoxic activity.
Cancer immunology, immunotherapy : CII 1994;38(4):265-71.
1993: Parra E; Wingren A G; Hedlund G; Sjögren H O; Kalland T; Sansom D; Dohlsten M
Human naive and memory T-helper cells display distinct adhesion properties to ICAM-1, LFA-3 and B7 molecules.
Scandinavian journal of immunology 1993;38(6):508-14.
1993: Akerblom E; Dohlsten M; Brynö C; Mastej M; Steringer I; Hedlund G; Lando P; Kalland T
Preparation and characterization of conjugates of monoclonal antibodies and staphylococcal enterotoxin A using a new hydrophilic cross-linker.
Bioconjugate chemistry 1993;4(6):455-66.
1993: Lando P A; Dohlsten M; Hedlund G; Brodin T; Sansom D; Kalland T
Co-stimulation with B7 and targeted superantigen is required for MHC class II-independent T-cell proliferation but not cytotoxicity.
Immunology 1993;80(2):236-41.
1993: Wallgren A; Festin R; Gidlöf C; Dohlsten M; Kalland T; Tötterman T H
Efficient killing of chronic B-lymphocytic leukemia cells by superantigen-directed T cells.
Blood 1993;82(4):1230-8.
1993: Dohlsten M; Björklund M; Sundstedt A; Hedlund G; Samson D; Kalland T
Immunopharmacology of the superantigen staphylococcal enterotoxin A in T-cell receptor V beta 3 transgenic mice.
Immunology 1993;79(4):520-7.
1993: Dohlsten M; Sundstedt A; Björklund M; Hedlund G; Kalland T
Superantigen-induced cytokines suppress growth of human colon-carcinoma cells.
International journal of cancer. Journal international du cancer 1993;54(3):482-8.
1993: Kalland T; Dohlsten M; Abrahmsén L; Hedlund G; Björk P; Lando P A; Sundstedt A; Akerblom E; Lind P
Targeting of superantigens.
Cell biophysics 1993;22(1-3):147-64.
1993: Lando P A; Dohlsten M; Hedlund G; Akerblom E; Kalland T
T cell killing of human colon carcinomas by monoclonal-antibody-targeted superantigens.
Cancer immunology, immunotherapy : CII 1993;36(4):223-8.
1993: Hedlund G; Dohlsten M; Petersson C; Kalland T
Superantigen-based tumor therapy: in vivo activation of cytotoxic T cells.
Cancer immunology, immunotherapy : CII 1993;36(2):89-93.
1993: Kalland T; Dohlsten M; Lind P; Sundstedt A; Abrahmsén L; Hedlund G; Björk P; Lando P A; Björklund M
Monoclonal antibodies and superantigens: a novel therapeutic approach.
Medical oncology and tumor pharmacotherapy 1993;10(1-2):37-47.
1992: Hansson J; Ericsson P O; Dohlsten M; Sjögren H O; Kalland T; Hedlund G
Locally superantigen-activated peritoneal cytolytic T lymphocytes belong to the CD8+ CD45RC- subset and lyse MHC class II+ tumor cells.
Immunology letters 1992;34(3):229-36.
1992: Ericsson P O; Hansson J; Dohlsten M; Sjögren H O; Hiserodt J C; Hedlund G
In vivo induced allo-reactive natural killer cells.
Journal of immunology (Baltimore, Md. : 1950) 1992;149(5):1504-9.
1992: Gjörloff A; Hedlund G; Kalland T; Sansom D; Fischer H; Trowsdale J; Sjögren H O; Dohlsten M
The LFA-3 adhesion pathway is differently utilized by superantigen-activated human CD4+ T-cell subsets.
Scandinavian journal of immunology 1992;36(2):243-50.
1992: Fischer H; Gjörloff A; Hedlund G; Hedman H; Lundgren E; Kalland T; Sjögren H O; Dohlsten M
Stimulation of human naive and memory T helper cells with bacterial superantigen. Naive CD4+45RA+ T cells require a costimulatory signal mediated through the LFA-1/ICAM-1 pathway.
Journal of immunology (Baltimore, Md. : 1950) 1992;148(7):1993-8.
1991: Hedlund G; Dohlsten M; Herrmann T; Buell G; Lando P A; Segrén S; Schrimsher J; MacDonald H R; Sjögren H O; Kalland T
A recombinant C-terminal fragment of staphylococcal enterotoxin A binds to human MHC class II products but does not activate T cells.
Journal of immunology (Baltimore, Md. : 1950) 1991;147(12):4082-5.
1991: Ericsson P O; Hansson J; Widegren B; Dohlsten M; Sjögren H O; Hedlund G
In vivo induction of gamma/delta T cells with highly potent and selective anti-tumor cytotoxicity.
European journal of immunology 1991;21(11):2797-802.
1991: Dohlsten M; Hedlund G; Akerblom E; Lando P A; Kalland T
Monoclonal antibody-targeted superantigens: a different class of anti-tumor agents.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(20):9287-91.
1991: Gjörloff A; Fischer H; Hedlund G; Hansson J; Kenney J S; Allison A C; Sjögren H O; Dohlsten M
Induction of interleukin-1 in human monocytes by the superantigen staphylococcal enterotoxin A requires the participation of T cells.
Cellular immunology 1991;137(1):61-71.
1991: Ericsson P O; Lindén O; Dohlsten M; Sjögren H O; Hedlund G
Functions of rat CD4+ T cell subsets defined by CD45RB: CD45RB- cells have a much stronger response to recall antigens, whereas polyclonally activated cells of both subsets are equally efficient producers of IFN in the presence of exogenous IL-2.
Cellular immunology 1991;132(2):391-9.
1991: Lando P A; Hedlund G; Dohlsten M; Kalland T
Bacterial superantigens as anti-tumour agents: induction of tumour cytotoxicity in human lymphocytes by staphylococcal enterotoxin A.
Cancer immunology, immunotherapy : CII 1991;33(4):231-7.
1991: Kalland T; Hedlund G; Dohlsten M; Lando P A
Staphylococcal enterotoxin-dependent cell-mediated cytotoxicity.
Current topics in microbiology and immunology 1991;174():81-92.
1990: Fischer H; Hedlund G; Kalland T; Sjögren H O; Dohlsten M
Independent regulation of IFN-gamma and tumor necrosis factor by IL-1 in human T helper cells.
Journal of immunology (Baltimore, Md. : 1950) 1990;145(11):3767-72.
1990: Kristensson K; Dohlsten M; Fischer H; Ericsson P O; Hedlund G; Sjögren H O; Carlsson R
Phenotypical and functional differentiation of CD4+ CD45RA+ human T cells following polyclonal activation.
Scandinavian journal of immunology 1990;32(3):243-53.
1990: Fischer H; Dohlsten M; Andersson U; Hedlund G; Ericsson P; Hansson J; Sjögren H O
Production of TNF-alpha and TNF-beta by staphylococcal enterotoxin A activated human T cells.
Journal of immunology (Baltimore, Md. : 1950) 1990;144(12):4663-9.
1990: Ericsson P O; Hedlund G; Hansson J; Dohlsten M; Sjögren H O
Tumor-selective cytolysis is executed exclusively by CD45R+ CTL whereas allo-specific cytotoxicity can be executed also by CD45R- CTL.
Cellular immunology 1990;126(1):69-79.
1989: Andersson U; Adolf G; Dohlsten M; Möller G; Sjögren H O
Characterization of individual tumor necrosis factor alpha-and beta-producing cells after polyclonal T cell activation.
Journal of immunological methods 1989;123(2):233-40.
1989: Ericsson P O; Hedlund G; Dohlsten M; Carlsson R; Sjögren H O
Gamma interferon induces the appearance of a CD4-, major histocompatibility complex class II+ macrophage subpopulation in the rat peritoneal cavity.
Scandinavian journal of immunology 1989;29(6):679-87.
1989: Fischer H; Dohlsten M; Lindvall M; Sjögren H O; Carlsson R
Binding of staphylococcal enterotoxin A to HLA-DR on B cell lines.
Journal of immunology (Baltimore, Md. : 1950) 1989;142(9):3151-7.
1989: Hedlund G; Dohlsten M; Ericsson P O; Sjögren H O
Rapid response to Con A by CD4+CD45R- rat memory lymphocytes as compared to CD4+CD45R+ lymphocytes.
Cellular immunology 1989;119(2):317-26.
1989: Dohlsten M; Hedlund G; Fischer H; Sjögren H O; Carlsson R
Proliferation of human CD4+45R+ and CD4+45R- T helper cells is promoted by both IL-2 and IL-4 while interferon-gamma production is restricted to IL-2 activated CD4+45R- T cells.
Immunology letters 1989;20(1):29-34.
1988: Dohlsten M; Kalland T; Sjögren H O; Carlsson R
Histamine inhibits interleukin 1 production by lipopolysaccharide-stimulated human peripheral blood monocytes.
Scandinavian journal of immunology 1988;27(5):527-32.
1988: Dohlsten M; Hedlund G; Bekassy A N; Lindén O; Garwicz S; Wiebe T; Sjögren H O; Carlsson R
Lymphocyte subpopulations and lymphokine production in children with constitutional aplastic anemia.
Pediatric hematology and oncology 1988;5(2):143-51.
1987: Dohlsten M; Sjögren H O; Carlsson R
Histamine acts directly on human T cells to inhibit interleukin-2 and interferon-gamma production.
Cellular immunology 1987;109(1):65-74.
1987: Lindén O; Dohlsten M; Boketoft A; Hedlund G; Sjögren H O
Catalase and lipopolysaccharide enhance proliferation in the rat mixed lymphocyte reaction.
Scandinavian journal of immunology 1987;26(3):223-8.
1986: Dohlsten M; Lindén O; Hedlund G; Sjögren H O; Diamantstein T; Carlsson R
Synergistic action of gamma interferon and catalase to reverse the suppressive effect of peritoneal macrophages on concanavalin A-induced lymphocyte proliferation.
Scandinavian journal of immunology 1986;24(1):49-58.
1986: Dohlsten M; Carlsson R; Hedlund G; Sjögren H O; Bekassy A N; Garwicz S
Immunological abnormalities in a child with constitutional aplastic anemia.
Pediatric hematology and oncology 1986;3(1):89-96.

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